General Information of Probe

Probe ID
LDPC0270
Probe Name
Johansson_61
Synonyms
SCHEMBL18763041
Probe Type
ABPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 380.9
Lipid-water partition coefficient (xlogp) 3.9
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C22H21ClN2O2
IUPAC Name
2-chloro-N-[1-(3-ethynylbenzoyl)piperidin-4-yl]-N-phenylacetamide
Canonical SMILES
C#CC1=CC(=CC=C1)C(=O)N2CCC(CC2)N(C3=CC=CC=C3)C(=O)CCl
InChI
InChI=1S/C22H21ClN2O2/c1-2-17-7-6-8-18(15-17)22(27)24-13-11-20(12-14-24)25(21(26)16-23)19-9-4-3-5-10-19/h1,3-10,15,20H,11-14,16H2
InChIKey
AOMPIUUSFRUOCF-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

138 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 _(5.94)  LDD1490 
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (HPGD) LDTP02788 _(20.00)  LDD1487 
2-aminoethanethiol dioxygenase (ADO) LDTP10828 _(10.85)  LDD1485 
3'-5' exoribonuclease 1 (ERI1) LDTP08482 _(20.00)  LDD1487 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 _(7.57)  LDD1485 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 _(20.00)  LDD1487 
ABC-type organic anion transporter ABCA8 (ABCA8) LDTP01459 _(20.00)  LDD1485 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 _(7.37)  LDD1485 
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) LDTP03458 _(20.00)  LDD1485 
ADP-ribosylation factor-like protein 1 (ARL1) LDTP03900 _(20.00)  LDD1490 
Alpha/beta hydrolase domain-containing protein 17B (ABHD17B) LDTP07208 _(4.04)  LDD1487 
Androgen-induced gene 1 protein (AIG1) LDTP12697 _(12.99)  LDD1487 
Antigen peptide transporter 1 (TAP1) LDTP05408 _(7.53)  LDD1490 
AP2-associated protein kinase 1 (AAK1) LDTP06699 _(20.00)  LDD1489 
Arsenite methyltransferase (AS3MT) LDTP12188 _(4.65)  LDD1490 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 _(10.23)  LDD1485 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 _(11.13)  LDD1487 
ATPase PAAT (PAAT) LDTP12057 _(20.00)  LDD1485 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 _(11.43)  LDD1485 
Caspase-10 (CASP10) LDTP09904 _(20.00)  LDD1485 
Caspase-8 (CASP8) LDTP06211 _(17.88)  LDD1485 
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (PDE3B) LDTP05845 _(4.32)  LDD1490 
Chitinase-3-like protein 2 (CHI3L2) LDTP06471 _(20.00)  LDD1487 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 _(18.43)  LDD1485 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 _(20.00)  LDD1485 
Chromodomain-helicase-DNA-binding protein 1 (CHD1) LDTP00394 _(20.00)  LDD1485 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 _(15.21)  LDD1485 
Creatine kinase B-type (CKB) LDTP02616 _(20.00)  LDD1487 
Creatine kinase U-type, mitochondrial (CKMT1A; CKMT1B) LDTP02622 _(20.00)  LDD1485 
Cyclin-dependent kinase 18 (CDK18) LDTP05507 _(20.00)  LDD1485 
Cystathionine gamma-lyase (CTH) LDTP03656 _(10.17)  LDD1485 
Cytochrome b5 type B (CYB5B) LDTP00697 _(10.95)  LDD1485 
Cytosolic iron-sulfur assembly component 3 (CIAO3) LDTP11990 _(4.66)  LDD1487 
DDB1- and CUL4-associated factor 11 (DCAF11) LDTP09490 _(11.86)  LDD1485 
Dehydrogenase/reductase SDR family member 13 (DHRS13) LDTP15154 _(20.00)  LDD1485 
DGAT1/2-independent enzyme synthesizing storage lipids (TMEM68) LDTP19892 _(5.34)  LDD1485 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 _(20.00)  LDD1490 
DNA fragmentation factor subunit beta (DFFB) LDTP01394 _(14.99)  LDD1485 
DNA-directed RNA polymerase II subunit RPB1 (POLR2A) LDTP03298 _(10.27)  LDD1487 
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3) LDTP09841 _(15.05)  LDD1485 
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG6) LDTP14213 _(11.67)  LDD1485 
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) LDTP05953 _(20.00)  LDD1485 
E3 ISG15--protein ligase HERC5 (HERC5) LDTP13349 _(4.06)  LDD1490 
E3 ubiquitin-protein ligase BRE1A (RNF20) LDTP07218 _(6.33)  LDD1485 
E3 ubiquitin-protein ligase BRE1B (RNF40) LDTP01141 _(20.00)  LDD1485 
E3 ubiquitin-protein ligase RNF139 (RNF139) LDTP09556 _(20.00)  LDD1487 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 _(7.05)  LDD1485 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 _(4.64)  LDD1485 
ERO1-like protein alpha (ERO1A) LDTP10386 _(7.07)  LDD1485 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 _(11.75)  LDD1485 
Glutamine--tRNA ligase (QARS1) LDTP04135 _(4.16)  LDD1485 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 _(20.00)  LDD1485 
Glycerol-3-phosphate acyltransferase 4 (GPAT4) LDTP08232 _(16.16)  LDD1485 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 _(7.46)  LDD1485 
GPI ethanolamine phosphate transferase 3 (PIGO) LDTP09505 _(20.00)  LDD1485 
GTP-binding protein 4 (GTPBP4) LDTP11529 _(20.00)  LDD1488 
GTPase IMAP family member 2 (GIMAP2) LDTP13219 _(15.94)  LDD1485 
GTPase NRas (NRAS) LDTP01825 _(20.00)  LDD1491 
HBS1-like protein (HBS1L) LDTP14019 _(20.00)  LDD1485 
Helicase ARIP4 (RAD54L2) LDTP14036 _(20.00)  LDD1485 
Heme oxygenase 2 (HMOX2) LDTP03540 _(8.24)  LDD1485 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 _(6.03)  LDD1490 
Large ribosomal subunit protein mL39 (MRPL39) LDTP12835 _(17.82)  LDD1485 
Lysine-specific demethylase 6A (KDM6A) LDTP00678 _(5.42)  LDD1485 
Methylated-DNA--protein-cysteine methyltransferase (MGMT) LDTP02852 _(15.53)  LDD1485 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 _(4.80)  LDD1487 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 _(6.21)  LDD1485 
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) LDTP09598 _(9.18)  LDD1485 
Mitogen-activated protein kinase kinase kinase 4 (MAP3K4) LDTP14291 _(20.00)  LDD1485 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 _(20.00)  LDD1485 
NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) LDTP01986 _(20.00)  LDD1487 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 _(11.87)  LDD1485 
Nuclear prelamin A recognition factor (NARF) LDTP13302 _(5.78)  LDD1485 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 _(20.00)  LDD1490 
Palmitoyltransferase ZDHHC4 (ZDHHC4) LDTP12362 _(20.00)  LDD1490 
Peptidyl-tRNA hydrolase (PTRH1) LDTP17604 _(4.07)  LDD1488 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 _(9.26)  LDD1487 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) LDTP00252 _(6.74)  LDD1485 
Phosphatidylinositol 4-kinase beta (PI4KB) LDTP13112 _(10.42)  LDD1488 
Phosphatidylserine lipase ABHD16A (ABHD16A) LDTP01704 _(4.13)  LDD1485 
Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4) LDTP03831 _(20.00)  LDD1485 
Polyprenol reductase (SRD5A3) LDTP12064 _(20.00)  LDD1485 
Presequence protease, mitochondrial (PITRM1) LDTP07003 _(20.00)  LDD1490 
Probable ATP-dependent RNA helicase DDX20 (DDX20) LDTP13285 _(7.16)  LDD1488 
Probable ATP-dependent RNA helicase DDX46 (DDX46) LDTP07932 _(10.28)  LDD1487 
Probable ATP-dependent RNA helicase DDX52 (DDX52) LDTP13904 _(8.90)  LDD1485 
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein (ASMTL) LDTP01647 _(20.00)  LDD1490 
Probable E3 ubiquitin-protein ligase MARCHF10 (MARCHF10) LDTP09023 _(20.00)  LDD1485 
Probable methyltransferase TARBP1 (TARBP1) LDTP05850 _(20.00)  LDD1485 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 _(20.00)  LDD1485 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 _(20.00)  LDD1485 
Prostamide/prostaglandin F synthase (PRXL2B) LDTP09344 _(9.59)  LDD1485 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 _(10.39)  LDD1485 
Protein adenylyltransferase SelO, mitochondrial (SELENOO) LDTP11294 _(19.53)  LDD1485 
Protein argonaute-2 (AGO2) LDTP13492 _(20.00)  LDD1485 
Protein kinase C theta type (PRKCQ) LDTP05433 _(20.00)  LDD1485 
Protein mono-ADP-ribosyltransferase PARP10 (PARP10) LDTP06900 _(8.17)  LDD1485 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 _(11.53)  LDD1489 
Pseudouridylate synthase RPUSD2 (RPUSD2) LDTP15370 _(5.86)  LDD1485 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 _(20.00)  LDD1488 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 _(20.00)  LDD1488 
Quinone oxidoreductase (CRYZ) LDTP05551 _(20.00)  LDD1490 
Replication factor C subunit 4 (RFC4) LDTP03725 _(10.46)  LDD1485 
Retinal dehydrogenase 2 (ALDH1A2) LDTP01419 _(10.81)  LDD1487 
Rho family-interacting cell polarization regulator 1 (RIPOR1) LDTP07819 _(4.25)  LDD1487 
Rho-related GTP-binding protein RhoC (RHOC) LDTP02248 _(20.00)  LDD1490 
Ribonuclease H2 subunit A (RNASEH2A) LDTP01311 _(7.07)  LDD1488 
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) LDTP03592 _(20.00)  LDD1490 
Ribosomal protein S6 kinase alpha-2 (RPS6KA2) LDTP06363 _(6.05)  LDD1489 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 _(4.47)  LDD1485 
rRNA methyltransferase 2, mitochondrial (MRM2) LDTP13330 _(20.00)  LDD1488 
rRNA methyltransferase 3, mitochondrial (MRM3) LDTP12215 _(20.00)  LDD1488 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 _(9.14)  LDD1485 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3) LDTP09976 _(5.64)  LDD1485 
Secernin-2 (SCRN2) LDTP15725 _(7.69)  LDD1488 
Secernin-3 (SCRN3) LDTP17022 _(4.69)  LDD1485 
Selenide, water dikinase 1 (SEPHS1) LDTP04328 _(10.56)  LDD1485 
Selenide, water dikinase 2 (SEPHS2) LDTP10917 _(10.37)  LDD1485 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 _(15.03)  LDD1485 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 _(20.00)  LDD1490 
Squalene monooxygenase (SQLE) LDTP06142 _(4.18)  LDD1487 
Sterol carrier protein 2 (SCP2) LDTP03163 _(9.11)  LDD1485 
Terminal nucleotidyltransferase 5C (TENT5C) LDTP07242 _(10.30)  LDD1488 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 _(9.69)  LDD1485 
Thioredoxin reductase 2, mitochondrial (TXNRD2) LDTP12297 _(5.21)  LDD1485 
Thioredoxin reductase-like selenoprotein T (SELENOT) LDTP04988 _(20.00)  LDD1485 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 _(4.35)  LDD1487 
Thymidylate kinase (DTYMK) LDTP03258 _(20.00)  LDD1487 
Titin (TTN) LDTP09749 _(20.00)  LDD1485 
Transforming protein RhoA (RHOA) LDTP04927 _(20.00)  LDD1490 
Tribbles homolog 3 (TRIB3) LDTP10787 _(4.35)  LDD1485 
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (FTSJ1) LDTP13200 _(20.00)  LDD1485 
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (PIP4P1) LDTP08183 _(20.00)  LDD1485 
Tyrosine-protein kinase JAK1 (JAK1) LDTP03230 _(13.02)  LDD1485 
Ubiquitin carboxyl-terminal hydrolase 34 (USP34) LDTP07875 _(12.37)  LDD1485 
Ubiquitin carboxyl-terminal hydrolase 8 (USP8) LDTP03904 _(20.00)  LDD1486 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 _(10.45)  LDD1485 
Xyloside xylosyltransferase 1 (XXYLT1) LDTP09053 _(8.68)  LDD1487 
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⏷ Show the Full List of 138 Enzyme
27 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ATP-binding cassette sub-family F member 1 (ABCF1) LDTP09149 _(20.00)  LDD1487 
Battenin (CLN3) LDTP05814 _(6.41)  LDD1485 
CD81 antigen (CD81) LDTP04849 _(4.63)  LDD1485 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 _(4.82)  LDD1487 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 _(20.00)  LDD1485 
Gasdermin-E (GSDME) LDTP00970 _(20.00)  LDD1485 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 _(10.54)  LDD1489 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 _(20.00)  LDD1485 
Mixed lineage kinase domain-like protein (MLKL) LDTP09038 _(14.66)  LDD1485 
Nuclear pore complex protein Nup107 (NUP107) LDTP04800 _(5.69)  LDD1485 
Nuclear pore complex protein Nup133 (NUP133) LDTP09579 _(10.28)  LDD1488 
Nucleoporin NUP188 (NUP188) LDTP07064 _(20.00)  LDD1488 
Nucleoporin p54 (NUP54) LDTP08029 _(20.00)  LDD1485 
PRA1 family protein 2 (PRAF2) LDTP01060 _(4.08)  LDD1489 
Protein RFT1 homolog (RFT1) LDTP10073 _(20.00)  LDD1485 
Rapamycin-insensitive companion of mTOR (RICTOR) LDTP07626 _(20.00)  LDD1490 
Reticulophagy regulator 1 (RETREG1) LDTP11987 _(20.00)  LDD1489 
Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 _(20.00)  LDD1490 
Sodium-dependent multivitamin transporter (SLC5A6) LDTP13834 _(20.00)  LDD1487 
Stimulator of interferon genes protein (STING1) LDTP08344 _(7.53)  LDD1485 
Store-operated calcium entry-associated regulatory factor (SARAF) LDTP10148 _(5.15)  LDD1487 
SUN domain-containing protein 1 (SUN1) LDTP01454 _(7.09)  LDD1485 
Transferrin receptor protein 1 (TFRC) LDTP01969 _(20.00)  LDD1485 
Transmembrane emp24 domain-containing protein 1 (TMED1) LDTP05875 _(11.65)  LDD1485 
Transmembrane protein 187 (TMEM187) LDTP06170 _(20.00)  LDD1487 
Transmembrane protein 245 (TMEM245) LDTP15979 _(11.55)  LDD1485 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 _(5.62)  LDD1490 
------------------------------------------------------------------------------------
⏷ Show the Full List of 27 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DNA-binding protein RFX7 (RFX7) LDTP06690 _(15.32)  LDD1489 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 _(4.01)  LDD1485 
Transcription factor Dp-1 (TFDP1) LDTP06073 _(10.18)  LDD1488 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Tapasin (TAPBP) LDTP00671 _(12.32)  LDD1490 
------------------------------------------------------------------------------------
88 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Albumin (ALB) LDTP01963 _(20.00)  LDD1485 
AMMECR1-like protein (AMMECR1L) LDTP19476 _(20.00)  LDD1485 
Ankyrin repeat and KH domain-containing protein 1 (ANKHD1) LDTP08573 _(20.00)  LDD1485 
Ankyrin repeat and SOCS box protein 3 (ASB3) LDTP14095 _(8.01)  LDD1485 
Asparagine synthetase domain-containing protein 1 (ASNSD1) LDTP18479 _(7.48)  LDD1485 
BTB/POZ domain-containing protein KCTD3 (KCTD3) LDTP16289 _(20.00)  LDD1487 
Calcineurin B homologous protein 3 (TESC) LDTP10140 _(13.53)  LDD1487 
Calcineurin-binding protein cabin-1 (CABIN1) LDTP14260 _(4.20)  LDD1487 
CD82 antigen (CD82) LDTP03399 _(14.15)  LDD1485 
Centriolar coiled-coil protein of 110 kDa (CCP110) LDTP00737 _(11.29)  LDD1485 
Centromere protein P (CENPP) LDTP07419 _(20.00)  LDD1485 
Coatomer subunit alpha (COPA) LDTP04571 _(20.00)  LDD1490 
Coatomer subunit delta (ARCN1) LDTP04181 _(20.00)  LDD1485 
Coiled-coil domain-containing protein 97 (CCDC97) LDTP19860 _(8.94)  LDD1485 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 _(4.51)  LDD1485 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 _(10.27)  LDD1489 
Cyclin-T1 (CCNT1) LDTP01002 _(20.00)  LDD1489 
Cytochrome b-245 chaperone 1 (CYBC1) LDTP11068 _(20.00)  LDD1488 
Cytochrome c oxidase copper chaperone (COX17) LDTP06030 _(10.82)  LDD1486 
Cytosolic iron-sulfur assembly component 2B (CIAO2B) LDTP13979 _(5.28)  LDD1485 
DDB1- and CUL4-associated factor 10 (DCAF10) LDTP07050 _(20.00)  LDD1487 
DENN domain-containing protein 2D (DENND2D) LDTP18400 _(20.00)  LDD1487 
DNA fragmentation factor subunit alpha (DFFA) LDTP00239 _(4.58)  LDD1487 
Fanconi anemia group I protein (FANCI) LDTP12680 _(7.29)  LDD1485 
GATOR1 complex protein NPRL3 (NPRL3) LDTP05714 _(20.00)  LDD1485 
General transcription factor 3C polypeptide 1 (GTF3C1) LDTP05648 _(10.60)  LDD1489 
Girdin (CCDC88A) LDTP06804 _(20.00)  LDD1486 
Glutathione S-transferase C-terminal domain-containing protein (GSTCD) LDTP17802 _(18.54)  LDD1485 
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (GBF1) LDTP09783 _(10.36)  LDD1485 
Golgin subfamily A member 3 (GOLGA3) LDTP05556 _(20.00)  LDD1488 
Growth factor receptor-bound protein 10 (GRB10) LDTP05825 _(20.00)  LDD1485 
Hemoglobin subunit theta-1 (HBQ1) LDTP14591 _(20.00)  LDD1487 
Inner centromere protein (INCENP) LDTP12432 _(20.00)  LDD1486 
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) LDTP12904 _(20.00)  LDD1489 
Integrin beta-2 (ITGB2) LDTP02077 _(20.00)  LDD1491 
Kelch-like ECH-associated protein 1 (KEAP1) LDTP06051 _(5.06)  LDD1485 
Keratin, type I cytoskeletal 10 (KRT10) LDTP02674 _(20.00)  LDD1487 
Keratin, type I cytoskeletal 16 (KRT16) LDTP02308 _(20.00)  LDD1490 
Keratin, type II cytoskeletal 1 (KRT1) LDTP02031 _(10.07)  LDD1485 
Keratin, type II cytoskeletal 2 epidermal (KRT2) LDTP03792 _(10.01)  LDD1485 
Keratin, type II cytoskeletal 79 (KRT79) LDTP07272 _(20.00)  LDD1486 
Lipoma-preferred partner (LPP) LDTP09969 _(20.00)  LDD1489 
Mdm2-binding protein (MTBP) LDTP15714 _(11.90)  LDD1490 
Multifunctional methyltransferase subunit TRM112-like protein (TRMT112) LDTP13323 _(4.30)  LDD1485 
Multivesicular body subunit 12A (MVB12A) LDTP10284 _(20.00)  LDD1488 
Nuclear protein AMMECR1 (AMMECR1) LDTP14076 _(20.00)  LDD1485 
Oxysterol-binding protein-related protein 3 (OSBPL3) LDTP11930 _(20.00)  LDD1485 
Oxysterol-binding protein-related protein 6 (OSBPL6) LDTP11533 _(11.11)  LDD1485 
PALM2-AKAP2 fusion protein (PALM2AKAP2) LDTP16261 _(20.00)  LDD1485 
Perilipin-3 (PLIN3) LDTP01021 _(7.35)  LDD1485 
Peroxiredoxin-like 2A (PRXL2A) LDTP11140 _(20.00)  LDD1485 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 _(20.00)  LDD1491 
Protein FAM118B (FAM118B) LDTP15852 _(4.57)  LDD1487 
Protein fem-1 homolog B (FEM1B) LDTP13431 _(4.69)  LDD1485 
Protein MMS22-like (MMS22L) LDTP07814 _(5.86)  LDD1487 
Protein MTO1 homolog, mitochondrial (MTO1) LDTP13936 _(10.56)  LDD1485 
Protein unc-13 homolog D (UNC13D) LDTP07888 _(10.36)  LDD1485 
Protein unc-45 homolog A (UNC45A) LDTP11890 _(10.31)  LDD1488 
R3H domain-containing protein 1 (R3HDM1) LDTP17044 _(20.00)  LDD1485 
RAS guanyl-releasing protein 2 (RASGRP2) LDTP07986 _(10.57)  LDD1485 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 _(9.78)  LDD1487 
Reticulon-3 (RTN3) LDTP01522 _(16.46)  LDD1485 
Reticulon-4 (RTN4) LDTP12412 _(15.99)  LDD1489 
Retinoblastoma-like protein 2 (RBL2) LDTP05578 _(20.00)  LDD1485 
RUS family member 1 (RUSF1) LDTP10357 _(5.43)  LDD1485 
SCL-interrupting locus protein (STIL) LDTP06397 _(20.00)  LDD1491 
Selenoprotein F (SELENOF) LDTP01012 _(7.83)  LDD1485 
Selenoprotein H (SELENOH) LDTP19672 _(11.82)  LDD1485 
Selenoprotein K (SELENOK) LDTP14236 _(20.00)  LDD1485 
Selenoprotein S (SELENOS) LDTP11075 _(20.00)  LDD1485 
SLIT-ROBO Rho GTPase-activating protein 2 (SRGAP2) LDTP01105 _(20.00)  LDD1485 
Splicing regulatory glutamine/lysine-rich protein 1 (SREK1) LDTP09684 _(20.00)  LDD1485 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 _(10.37)  LDD1488 
Syntaxin-8 (STX8) LDTP13664 _(13.09)  LDD1487 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 _(20.00)  LDD1490 
Target of rapamycin complex subunit LST8 (MLST8) LDTP11280 _(7.37)  LDD1487 
TBC1 domain family member 31 (TBC1D31) LDTP10221 _(5.02)  LDD1487 
TRAF3-interacting JNK-activating modulator (TRAF3IP3) LDTP13786 _(11.11)  LDD1485 
Transcription elongation factor SPT5 (SUPT5H) LDTP00236 _(20.00)  LDD1485 
Transcription elongation regulator 1 (TCERG1) LDTP00430 _(11.17)  LDD1487 
Trinucleotide repeat-containing gene 6B protein (TNRC6B) LDTP13710 _(10.29)  LDD1487 
Tubulin epsilon and delta complex protein 1 (TEDC1) LDTP15278 _(20.00)  LDD1485 
Tubulin-specific chaperone E (TBCE) LDTP06479 _(10.32)  LDD1485 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 _(17.33)  LDD1485 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 _(12.73)  LDD1485 
Vacuolar protein sorting-associated protein 51 homolog (VPS51) LDTP13338 _(9.80)  LDD1485 
YLP motif-containing protein 1 (YLPM1) LDTP04290 _(20.00)  LDD1486 
Zinc finger CCCH domain-containing protein 7B (ZC3H7B) LDTP13245 _(10.30)  LDD1487 
------------------------------------------------------------------------------------
⏷ Show the Full List of 88 Other

Competitor(s) Related To This Probe

Competitor ID Name Concentration Cell-system Ref
 LDCM0569  Fragment7 7.5 uM Human T acute lymphoblastic leukemia cell lysate (Jurkat) [1]
 LDCM0615  Fragment63-R 7.5 uM Human T acute lymphoblastic leukemia cell lysate (Jurkat) [1]
 LDCM0616  Fragment61 30 uM Human T acute lymphoblastic leukemia cell lysate (Jurkat) [1]
 LDCM0617  Fragment63-S 7.5 uM Human T acute lymphoblastic leukemia cell lysate (Jurkat) [1]

Full Information of The Labelling Profiles of This Probe

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment7
Competitor Concentration
30 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment7
Competitor Concentration
7.5 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment63-R
Competitor Concentration
30 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID
  
Experiment 4 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment63-R
Competitor Concentration
7.5 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID
  
Experiment 5 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment61
Competitor Concentration
30 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID
  
Experiment 6 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment63-S
Competitor Concentration
30 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID
  
Experiment 7 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
10 uM
Quantitative Method
SILAC
Competitor Name
Fragment63-S
Competitor Concentration
7.5 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Bone marrow
Disease Model
T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name
Human T acute lymphoblastic leukemia cell lysate (Jurkat)
Interaction Atlas ID

References

1 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.