Details of the Target

General Information of Target

Target ID LDTP08029
Target Name Nucleoporin p54 (NUP54)
Gene Name NUP54
Gene ID 53371
Synonyms
Nucleoporin p54; 54 kDa nucleoporin
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG
FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT
ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC
MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV
VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP
PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE
LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE
LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI
IKDDLEDIKLVEHGLNETIHIRGGVFS
Target Bioclass
Transporter and channel
Family
NUP54 family
Subcellular location
Nucleus, nuclear pore complex
Function Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Uniprot ID
Q7Z3B4
Ensemble ID
ENST00000264883.8
HGNC ID
HGNC:17359

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
DU145 SNV: p.K215E DBIA    Probe Info 
HGC27 SNV: p.T252I DBIA    Probe Info 
KMCH1 SNV: p.S383C DBIA    Probe Info 
NCIH1993 SNV: p.F164I .
SKOV3 Deletion: p.D135CfsTer23 DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 25 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
STPyne
 Probe Info  		K338(10.00); K428(10.00)  LDD0277  [2]
Probe 1
 Probe Info  		Y401(20.91)  LDD3495  [3]
BTD
 Probe Info  		C180(1.12)  LDD2090  [4]
Sulforaphane-probe2
 Probe Info  		2.20  LDD0160  [5]
Johansson_61
 Probe Info  		_(20.00)  LDD1485  [6]
AHL-Pu-1
 Probe Info  		C180(2.03)  LDD0172  [7]
HHS-475
 Probe Info  		Y401(0.53)  LDD0264  [8]
Acrolein
 Probe Info  		N.A.  LDD0222  [9]
DBIA
 Probe Info  		C180(1.11)  LDD0078  [10]
5E-2FA
 Probe Info  		H214(0.00); H264(0.00)  LDD2235  [11]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [12]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [13]
Lodoacetamide azide
 Probe Info  		C180(0.00); C171(0.00)  LDD0037  [12]
WYneN
 Probe Info  		N.A.  LDD0021  [14]
Compound 10
 Probe Info  		N.A.  LDD2216  [15]
Compound 11
 Probe Info  		N.A.  LDD2213  [15]
IPM
 Probe Info  		N.A.  LDD0005  [14]
TFBX
 Probe Info  		N.A.  LDD0148  [16]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [17]
1c-yne
 Probe Info  		K321(0.00); K140(0.00)  LDD0228  [18]
AOyne
 Probe Info  		15.00  LDD0443  [19]
NAIA_5
 Probe Info  		N.A.  LDD2223  [20]
HHS-465
 Probe Info  		N.A.  LDD2240  [21]
HHS-482
 Probe Info  		Y453(0.64)  LDD2239  [22]
PAL-AfBPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C092
 Probe Info  		68.12  LDD1783  [23]
C106
 Probe Info  		17.15  LDD1793  [23]
C313
 Probe Info  		13.27  LDD1980  [23]
FFF probe11
 Probe Info  		7.62  LDD0472  [24]
FFF probe2
 Probe Info  		20.00  LDD0463  [24]
FFF probe3
 Probe Info  		14.58  LDD0465  [24]
STS-1
 Probe Info  		N.A.  LDD0137  [25]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C180(1.00)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C180(1.38)  LDD2152  [4]
 LDCM0025  4SU-RNA HEK-293T C180(2.03)  LDD0172  [7]
 LDCM0214  AC1 HCT 116 C171(0.92); C180(1.18)  LDD0531  [10]
 LDCM0215  AC10 HCT 116 C171(0.96); C180(1.17)  LDD0532  [10]
 LDCM0216  AC100 HCT 116 C171(1.28); C180(1.18)  LDD0533  [10]
 LDCM0217  AC101 HCT 116 C171(1.22); C180(1.12)  LDD0534  [10]
 LDCM0218  AC102 HCT 116 C171(1.31); C180(1.07)  LDD0535  [10]
 LDCM0219  AC103 HCT 116 C171(1.17); C180(1.28)  LDD0536  [10]
 LDCM0220  AC104 HCT 116 C171(1.36); C180(1.17)  LDD0537  [10]
 LDCM0221  AC105 HCT 116 C171(1.19); C180(1.27)  LDD0538  [10]
 LDCM0222  AC106 HCT 116 C171(1.23); C180(1.33)  LDD0539  [10]
 LDCM0223  AC107 HCT 116 C171(1.20); C180(1.32)  LDD0540  [10]
 LDCM0224  AC108 HCT 116 C171(1.16); C180(1.10)  LDD0541  [10]
 LDCM0225  AC109 HCT 116 C171(1.22); C180(0.86)  LDD0542  [10]
 LDCM0226  AC11 HCT 116 C171(0.83); C180(1.41)  LDD0543  [10]
 LDCM0227  AC110 HCT 116 C171(1.50); C180(1.04)  LDD0544  [10]
 LDCM0228  AC111 HCT 116 C171(1.26); C180(1.06)  LDD0545  [10]
 LDCM0229  AC112 HCT 116 C171(0.98); C180(1.17)  LDD0546  [10]
 LDCM0230  AC113 HCT 116 C171(1.11); C180(1.00)  LDD0547  [10]
 LDCM0231  AC114 HCT 116 C171(1.06); C180(1.16)  LDD0548  [10]
 LDCM0232  AC115 HCT 116 C171(1.03); C180(1.34)  LDD0549  [10]
 LDCM0233  AC116 HCT 116 C171(0.94); C180(1.43)  LDD0550  [10]
 LDCM0234  AC117 HCT 116 C171(1.11); C180(1.14)  LDD0551  [10]
 LDCM0235  AC118 HCT 116 C171(0.95); C180(1.02)  LDD0552  [10]
 LDCM0236  AC119 HCT 116 C171(0.98); C180(1.14)  LDD0553  [10]
 LDCM0237  AC12 HCT 116 C171(0.82); C180(1.16)  LDD0554  [10]
 LDCM0238  AC120 HCT 116 C171(0.82); C180(1.31)  LDD0555  [10]
 LDCM0239  AC121 HCT 116 C171(1.39); C180(1.11)  LDD0556  [10]
 LDCM0240  AC122 HCT 116 C171(1.06); C180(1.04)  LDD0557  [10]
 LDCM0241  AC123 HCT 116 C171(2.03); C180(1.09)  LDD0558  [10]
 LDCM0242  AC124 HCT 116 C171(1.13); C180(1.03)  LDD0559  [10]
 LDCM0243  AC125 HCT 116 C171(1.05); C180(1.07)  LDD0560  [10]
 LDCM0244  AC126 HCT 116 C171(1.01); C180(1.19)  LDD0561  [10]
 LDCM0245  AC127 HCT 116 C171(1.07); C180(1.24)  LDD0562  [10]
 LDCM0246  AC128 HCT 116 C171(0.99); C180(1.08)  LDD0563  [10]
 LDCM0247  AC129 HCT 116 C171(0.85); C180(1.25)  LDD0564  [10]
 LDCM0249  AC130 HCT 116 C171(0.88); C180(1.18)  LDD0566  [10]
 LDCM0250  AC131 HCT 116 C171(1.01); C180(1.18)  LDD0567  [10]
 LDCM0251  AC132 HCT 116 C171(0.91); C180(1.31)  LDD0568  [10]
 LDCM0252  AC133 HCT 116 C171(0.88); C180(1.26)  LDD0569  [10]
 LDCM0253  AC134 HCT 116 C171(0.85); C180(1.67)  LDD0570  [10]
 LDCM0254  AC135 HCT 116 C171(0.84); C180(1.24)  LDD0571  [10]
 LDCM0255  AC136 HCT 116 C171(0.86); C180(1.37)  LDD0572  [10]
 LDCM0256  AC137 HCT 116 C171(0.84); C180(1.45)  LDD0573  [10]
 LDCM0257  AC138 HCT 116 C171(0.84); C180(2.04)  LDD0574  [10]
 LDCM0258  AC139 HCT 116 C171(0.84); C180(1.64)  LDD0575  [10]
 LDCM0259  AC14 HCT 116 C171(1.07); C180(1.13)  LDD0576  [10]
 LDCM0260  AC140 HCT 116 C171(0.88); C180(2.08)  LDD0577  [10]
 LDCM0261  AC141 HCT 116 C171(0.79); C180(1.87)  LDD0578  [10]
 LDCM0262  AC142 HCT 116 C171(0.78); C180(1.41)  LDD0579  [10]
 LDCM0263  AC143 HCT 116 C171(0.82); C180(1.13)  LDD0580  [10]
 LDCM0264  AC144 HCT 116 C171(0.96); C180(1.38)  LDD0581  [10]
 LDCM0265  AC145 HCT 116 C171(0.91); C180(1.16)  LDD0582  [10]
 LDCM0266  AC146 HCT 116 C171(0.91); C180(1.30)  LDD0583  [10]
 LDCM0267  AC147 HCT 116 C171(1.08); C180(1.43)  LDD0584  [10]
 LDCM0268  AC148 HCT 116 C171(0.98); C180(1.87)  LDD0585  [10]
 LDCM0269  AC149 HCT 116 C171(0.89); C180(1.45)  LDD0586  [10]
 LDCM0270  AC15 HCT 116 C171(0.92); C180(1.13)  LDD0587  [10]
 LDCM0271  AC150 HCT 116 C171(0.97); C180(1.15)  LDD0588  [10]
 LDCM0272  AC151 HCT 116 C171(0.92); C180(1.18)  LDD0589  [10]
 LDCM0273  AC152 HCT 116 C171(0.95); C180(1.76)  LDD0590  [10]
 LDCM0274  AC153 HCT 116 C171(0.96); C180(2.22)  LDD0591  [10]
 LDCM0621  AC154 HCT 116 C171(0.93); C180(1.27)  LDD2158  [10]
 LDCM0622  AC155 HCT 116 C171(0.90); C180(1.35)  LDD2159  [10]
 LDCM0623  AC156 HCT 116 C171(0.99); C180(1.09)  LDD2160  [10]
 LDCM0624  AC157 HCT 116 C171(0.96); C180(0.97)  LDD2161  [10]
 LDCM0276  AC17 HCT 116 C171(0.87); C180(1.11)  LDD0593  [10]
 LDCM0277  AC18 HCT 116 C171(0.87); C180(1.44)  LDD0594  [10]
 LDCM0278  AC19 HCT 116 C171(0.87); C180(1.09)  LDD0595  [10]
 LDCM0279  AC2 HCT 116 C171(0.91); C180(1.05)  LDD0596  [10]
 LDCM0280  AC20 HCT 116 C171(0.88); C180(1.12)  LDD0597  [10]
 LDCM0281  AC21 HCT 116 C171(0.90); C180(1.18)  LDD0598  [10]
 LDCM0282  AC22 HCT 116 C171(0.94); C180(1.06)  LDD0599  [10]
 LDCM0283  AC23 HCT 116 C171(0.85); C180(1.23)  LDD0600  [10]
 LDCM0284  AC24 HCT 116 C180(0.97); C171(1.00)  LDD0601  [10]
 LDCM0285  AC25 HCT 116 C171(0.97); C180(1.08)  LDD0602  [10]
 LDCM0286  AC26 HCT 116 C171(0.90); C180(1.22)  LDD0603  [10]
 LDCM0287  AC27 HCT 116 C180(1.19); C171(1.21)  LDD0604  [10]
 LDCM0288  AC28 HCT 116 C171(1.13); C180(1.32)  LDD0605  [10]
 LDCM0289  AC29 HCT 116 C171(1.02); C180(1.28)  LDD0606  [10]
 LDCM0290  AC3 HCT 116 C171(0.86); C180(1.07)  LDD0607  [10]
 LDCM0291  AC30 HCT 116 C171(1.02); C180(1.30)  LDD0608  [10]
 LDCM0292  AC31 HCT 116 C171(0.97); C180(1.22)  LDD0609  [10]
 LDCM0293  AC32 HCT 116 C171(0.98); C180(1.47)  LDD0610  [10]
 LDCM0294  AC33 HCT 116 C171(0.91); C180(1.28)  LDD0611  [10]
 LDCM0295  AC34 HCT 116 C171(0.95); C180(1.55)  LDD0612  [10]
 LDCM0296  AC35 HCT 116 C180(0.93)  LDD0613  [10]
 LDCM0297  AC36 HCT 116 C180(0.88)  LDD0614  [10]
 LDCM0298  AC37 HCT 116 C180(0.86)  LDD0615  [10]
 LDCM0299  AC38 HCT 116 C180(0.93)  LDD0616  [10]
 LDCM0300  AC39 HCT 116 C180(0.99)  LDD0617  [10]
 LDCM0301  AC4 HCT 116 C171(0.90); C180(1.20)  LDD0618  [10]
 LDCM0302  AC40 HCT 116 C180(1.14)  LDD0619  [10]
 LDCM0303  AC41 HCT 116 C180(0.98)  LDD0620  [10]
 LDCM0304  AC42 HCT 116 C180(1.08)  LDD0621  [10]
 LDCM0305  AC43 HCT 116 C180(1.10)  LDD0622  [10]
 LDCM0306  AC44 HCT 116 C180(1.00)  LDD0623  [10]
 LDCM0307  AC45 HCT 116 C180(1.12)  LDD0624  [10]
 LDCM0308  AC46 HCT 116 C171(0.76); C180(1.13)  LDD0625  [10]
 LDCM0309  AC47 HCT 116 C171(0.68); C180(1.04)  LDD0626  [10]
 LDCM0310  AC48 HCT 116 C171(0.57); C180(1.05)  LDD0627  [10]
 LDCM0311  AC49 HCT 116 C171(0.82); C180(1.33)  LDD0628  [10]
 LDCM0312  AC5 HCT 116 C171(0.90); C180(1.25)  LDD0629  [10]
 LDCM0313  AC50 HCT 116 C171(0.59); C180(1.35)  LDD0630  [10]
 LDCM0314  AC51 HCT 116 C171(0.59); C180(0.99)  LDD0631  [10]
 LDCM0315  AC52 HCT 116 C171(0.75); C180(1.08)  LDD0632  [10]
 LDCM0316  AC53 HCT 116 C171(0.71); C180(1.23)  LDD0633  [10]
 LDCM0317  AC54 HCT 116 C171(0.85); C180(1.14)  LDD0634  [10]
 LDCM0318  AC55 HCT 116 C171(0.88); C180(1.22)  LDD0635  [10]
 LDCM0319  AC56 HCT 116 C171(0.68); C180(1.52)  LDD0636  [10]
 LDCM0320  AC57 HCT 116 C171(1.26); C180(1.43)  LDD0637  [10]
 LDCM0321  AC58 HCT 116 C171(0.96); C180(1.55)  LDD0638  [10]
 LDCM0322  AC59 HCT 116 C171(0.74); C180(1.58)  LDD0639  [10]
 LDCM0323  AC6 HCT 116 C171(1.00); C180(1.25)  LDD0640  [10]
 LDCM0324  AC60 HCT 116 C171(0.78); C180(1.42)  LDD0641  [10]
 LDCM0325  AC61 HCT 116 C171(0.91); C180(1.31)  LDD0642  [10]
 LDCM0326  AC62 HCT 116 C171(0.85); C180(1.67)  LDD0643  [10]
 LDCM0327  AC63 HCT 116 C171(0.94); C180(1.40)  LDD0644  [10]
 LDCM0328  AC64 HCT 116 C171(0.80); C180(1.67)  LDD0645  [10]
 LDCM0329  AC65 HCT 116 C171(0.86); C180(1.73)  LDD0646  [10]
 LDCM0330  AC66 HCT 116 C171(0.71); C180(1.48)  LDD0647  [10]
 LDCM0331  AC67 HCT 116 C171(0.84); C180(1.91)  LDD0648  [10]
 LDCM0332  AC68 HCT 116 C180(1.11)  LDD0649  [10]
 LDCM0333  AC69 HCT 116 C180(1.22)  LDD0650  [10]
 LDCM0334  AC7 HCT 116 C171(0.95); C180(1.15)  LDD0651  [10]
 LDCM0335  AC70 HCT 116 C180(1.21)  LDD0652  [10]
 LDCM0336  AC71 HCT 116 C180(1.02)  LDD0653  [10]
 LDCM0337  AC72 HCT 116 C180(1.20)  LDD0654  [10]
 LDCM0338  AC73 HCT 116 C180(1.62)  LDD0655  [10]
 LDCM0339  AC74 HCT 116 C180(1.55)  LDD0656  [10]
 LDCM0340  AC75 HCT 116 C180(1.70)  LDD0657  [10]
 LDCM0341  AC76 HCT 116 C180(1.24)  LDD0658  [10]
 LDCM0342  AC77 HCT 116 C180(1.26)  LDD0659  [10]
 LDCM0343  AC78 HCT 116 C180(1.12)  LDD0660  [10]
 LDCM0344  AC79 HCT 116 C180(1.16)  LDD0661  [10]
 LDCM0345  AC8 HCT 116 C171(0.89); C180(1.37)  LDD0662  [10]
 LDCM0346  AC80 HCT 116 C180(1.16)  LDD0663  [10]
 LDCM0347  AC81 HCT 116 C180(1.07)  LDD0664  [10]
 LDCM0348  AC82 HCT 116 C180(1.69)  LDD0665  [10]
 LDCM0349  AC83 HCT 116 C171(0.99); C180(1.58)  LDD0666  [10]
 LDCM0350  AC84 HCT 116 C171(1.15); C180(1.50)  LDD0667  [10]
 LDCM0351  AC85 HCT 116 C171(1.03); C180(1.39)  LDD0668  [10]
 LDCM0352  AC86 HCT 116 C171(0.92); C180(1.14)  LDD0669  [10]
 LDCM0353  AC87 HCT 116 C171(0.98); C180(1.04)  LDD0670  [10]
 LDCM0354  AC88 HCT 116 C171(0.88); C180(1.17)  LDD0671  [10]
 LDCM0355  AC89 HCT 116 C171(0.90); C180(1.32)  LDD0672  [10]
 LDCM0357  AC90 HCT 116 C180(0.93); C171(0.93)  LDD0674  [10]
 LDCM0358  AC91 HCT 116 C171(1.06); C180(1.68)  LDD0675  [10]
 LDCM0359  AC92 HCT 116 C171(0.98); C180(1.59)  LDD0676  [10]
 LDCM0360  AC93 HCT 116 C171(0.95); C180(1.44)  LDD0677  [10]
 LDCM0361  AC94 HCT 116 C171(1.28); C180(1.33)  LDD0678  [10]
 LDCM0362  AC95 HCT 116 C171(1.04); C180(1.17)  LDD0679  [10]
 LDCM0363  AC96 HCT 116 C171(1.07); C180(1.44)  LDD0680  [10]
 LDCM0364  AC97 HCT 116 C171(0.91); C180(1.60)  LDD0681  [10]
 LDCM0365  AC98 HCT 116 C171(1.05); C180(1.60)  LDD0682  [10]
 LDCM0366  AC99 HCT 116 C180(1.09); C171(1.20)  LDD0683  [10]
 LDCM0248  AKOS034007472 HCT 116 C171(0.89); C180(0.96)  LDD0565  [10]
 LDCM0356  AKOS034007680 HCT 116 C171(0.78); C180(1.16)  LDD0673  [10]
 LDCM0275  AKOS034007705 HCT 116 C171(0.83); C180(1.67)  LDD0592  [10]
 LDCM0020  ARS-1620 HCC44 C180(1.11)  LDD0078  [10]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [9]
 LDCM0632  CL-Sc Hep-G2 C180(0.93)  LDD2227  [20]
 LDCM0367  CL1 HCT 116 C180(0.96); C171(1.00)  LDD0684  [10]
 LDCM0368  CL10 HCT 116 C171(0.81); C180(1.41)  LDD0685  [10]
 LDCM0369  CL100 HCT 116 C171(0.86); C180(1.63)  LDD0686  [10]
 LDCM0370  CL101 HCT 116 C171(0.94); C180(1.83)  LDD0687  [10]
 LDCM0371  CL102 HCT 116 C171(0.98); C180(1.05)  LDD0688  [10]
 LDCM0372  CL103 HCT 116 C171(1.01); C180(1.04)  LDD0689  [10]
 LDCM0373  CL104 HCT 116 C171(0.81); C180(1.27)  LDD0690  [10]
 LDCM0374  CL105 HCT 116 C171(0.68); C180(1.65)  LDD0691  [10]
 LDCM0375  CL106 HCT 116 C171(0.80); C180(2.35)  LDD0692  [10]
 LDCM0376  CL107 HCT 116 C171(0.81); C180(1.40)  LDD0693  [10]
 LDCM0377  CL108 HCT 116 C171(0.88); C180(1.45)  LDD0694  [10]
 LDCM0378  CL109 HCT 116 C171(0.75); C180(1.93)  LDD0695  [10]
 LDCM0379  CL11 HCT 116 C171(0.94); C180(1.96)  LDD0696  [10]
 LDCM0380  CL110 HCT 116 C171(0.71); C180(1.57)  LDD0697  [10]
 LDCM0381  CL111 HCT 116 C171(0.84); C180(1.26)  LDD0698  [10]
 LDCM0382  CL112 HCT 116 C171(1.09); C180(1.35)  LDD0699  [10]
 LDCM0383  CL113 HCT 116 C171(0.92); C180(1.56)  LDD0700  [10]
 LDCM0384  CL114 HCT 116 C171(0.86); C180(1.70)  LDD0701  [10]
 LDCM0385  CL115 HCT 116 C171(0.97); C180(1.26)  LDD0702  [10]
 LDCM0386  CL116 HCT 116 C171(0.91); C180(1.22)  LDD0703  [10]
 LDCM0387  CL117 HCT 116 C180(1.42)  LDD0704  [10]
 LDCM0388  CL118 HCT 116 C180(1.01)  LDD0705  [10]
 LDCM0389  CL119 HCT 116 C180(1.12)  LDD0706  [10]
 LDCM0390  CL12 HCT 116 C171(0.90); C180(1.51)  LDD0707  [10]
 LDCM0391  CL120 HCT 116 C180(1.00)  LDD0708  [10]
 LDCM0392  CL121 HCT 116 C171(0.47); C180(1.28)  LDD0709  [10]
 LDCM0393  CL122 HCT 116 C171(0.78); C180(1.14)  LDD0710  [10]
 LDCM0394  CL123 HCT 116 C171(0.63); C180(1.17)  LDD0711  [10]
 LDCM0395  CL124 HCT 116 C171(1.02); C180(1.49)  LDD0712  [10]
 LDCM0396  CL125 HCT 116 C171(1.18); C180(1.39)  LDD0713  [10]
 LDCM0397  CL126 HCT 116 C180(1.28); C171(1.62)  LDD0714  [10]
 LDCM0398  CL127 HCT 116 C171(1.04); C180(1.15)  LDD0715  [10]
 LDCM0399  CL128 HCT 116 C171(0.66); C180(1.39)  LDD0716  [10]
 LDCM0400  CL13 HCT 116 C171(0.89); C180(1.33)  LDD0717  [10]
 LDCM0401  CL14 HCT 116 C171(0.91); C180(1.06)  LDD0718  [10]
 LDCM0402  CL15 HCT 116 C171(0.86); C180(1.27)  LDD0719  [10]
 LDCM0403  CL16 HCT 116 C171(0.77); C180(1.09)  LDD0720  [10]
 LDCM0404  CL17 HCT 116 C171(0.87); C180(1.11)  LDD0721  [10]
 LDCM0405  CL18 HCT 116 C171(0.74); C180(1.16)  LDD0722  [10]
 LDCM0406  CL19 HCT 116 C171(0.72); C180(1.10)  LDD0723  [10]
 LDCM0407  CL2 HCT 116 C171(0.94); C180(0.98)  LDD0724  [10]
 LDCM0408  CL20 HCT 116 C171(0.75); C180(1.34)  LDD0725  [10]
 LDCM0409  CL21 HCT 116 C171(0.73); C180(1.96)  LDD0726  [10]
 LDCM0410  CL22 HCT 116 C171(0.92); C180(1.67)  LDD0727  [10]
 LDCM0411  CL23 HCT 116 C171(0.83); C180(1.17)  LDD0728  [10]
 LDCM0412  CL24 HCT 116 C171(0.83); C180(1.60)  LDD0729  [10]
 LDCM0413  CL25 HCT 116 C171(0.68); C180(1.66)  LDD0730  [10]
 LDCM0414  CL26 HCT 116 C171(0.73); C180(1.20)  LDD0731  [10]
 LDCM0415  CL27 HCT 116 C171(0.78); C180(1.02)  LDD0732  [10]
 LDCM0416  CL28 HCT 116 C171(0.70); C180(1.72)  LDD0733  [10]
 LDCM0417  CL29 HCT 116 C171(0.74); C180(1.34)  LDD0734  [10]
 LDCM0418  CL3 HCT 116 C171(1.03); C180(1.04)  LDD0735  [10]
 LDCM0419  CL30 HCT 116 C171(0.69); C180(1.16)  LDD0736  [10]
 LDCM0420  CL31 HCT 116 C171(0.80); C180(1.17)  LDD0737  [10]
 LDCM0421  CL32 HCT 116 C171(0.74); C180(1.21)  LDD0738  [10]
 LDCM0422  CL33 HCT 116 C171(0.73); C180(1.39)  LDD0739  [10]
 LDCM0423  CL34 HCT 116 C171(0.88); C180(1.43)  LDD0740  [10]
 LDCM0424  CL35 HCT 116 C171(0.79); C180(1.34)  LDD0741  [10]
 LDCM0425  CL36 HCT 116 C171(0.72); C180(1.44)  LDD0742  [10]
 LDCM0426  CL37 HCT 116 C171(0.88); C180(1.47)  LDD0743  [10]
 LDCM0428  CL39 HCT 116 C171(0.72); C180(1.43)  LDD0745  [10]
 LDCM0429  CL4 HCT 116 C171(0.96); C180(1.09)  LDD0746  [10]
 LDCM0430  CL40 HCT 116 C171(0.76); C180(1.50)  LDD0747  [10]
 LDCM0431  CL41 HCT 116 C171(0.75); C180(1.44)  LDD0748  [10]
 LDCM0432  CL42 HCT 116 C171(0.91); C180(2.89)  LDD0749  [10]
 LDCM0433  CL43 HCT 116 C171(0.87); C180(1.51)  LDD0750  [10]
 LDCM0434  CL44 HCT 116 C171(0.78); C180(1.28)  LDD0751  [10]
 LDCM0435  CL45 HCT 116 C171(0.71); C180(1.42)  LDD0752  [10]
 LDCM0436  CL46 HCT 116 C171(0.92); C180(0.85)  LDD0753  [10]
 LDCM0437  CL47 HCT 116 C171(0.88); C180(0.90)  LDD0754  [10]
 LDCM0438  CL48 HCT 116 C171(0.87); C180(0.91)  LDD0755  [10]
 LDCM0439  CL49 HCT 116 C171(0.99); C180(0.90)  LDD0756  [10]
 LDCM0440  CL5 HCT 116 C171(1.04); C180(1.07)  LDD0757  [10]
 LDCM0441  CL50 HCT 116 C171(0.83); C180(1.46)  LDD0758  [10]
 LDCM0442  CL51 HCT 116 C171(0.94); C180(1.11)  LDD0759  [10]
 LDCM0443  CL52 HCT 116 C171(0.82); C180(0.87)  LDD0760  [10]
 LDCM0444  CL53 HCT 116 C171(0.92); C180(1.36)  LDD0761  [10]
 LDCM0445  CL54 HCT 116 C171(0.87); C180(0.86)  LDD0762  [10]
 LDCM0446  CL55 HCT 116 C171(0.93); C180(0.91)  LDD0763  [10]
 LDCM0447  CL56 HCT 116 C171(0.98); C180(1.10)  LDD0764  [10]
 LDCM0448  CL57 HCT 116 C171(0.95); C180(0.86)  LDD0765  [10]
 LDCM0449  CL58 HCT 116 C171(0.90); C180(0.83)  LDD0766  [10]
 LDCM0450  CL59 HCT 116 C171(1.04); C180(1.00)  LDD0767  [10]
 LDCM0451  CL6 HCT 116 C171(0.92); C180(1.42)  LDD0768  [10]
 LDCM0452  CL60 HCT 116 C171(0.98); C180(1.02)  LDD0769  [10]
 LDCM0453  CL61 HCT 116 C171(0.79); C180(1.15)  LDD0770  [10]
 LDCM0454  CL62 HCT 116 C171(0.82); C180(1.19)  LDD0771  [10]
 LDCM0455  CL63 HCT 116 C171(0.73); C180(1.38)  LDD0772  [10]
 LDCM0456  CL64 HCT 116 C171(0.68); C180(1.62)  LDD0773  [10]
 LDCM0457  CL65 HCT 116 C171(0.81); C180(1.24)  LDD0774  [10]
 LDCM0458  CL66 HCT 116 C171(0.80); C180(1.63)  LDD0775  [10]
 LDCM0459  CL67 HCT 116 C171(0.83); C180(1.43)  LDD0776  [10]
 LDCM0460  CL68 HCT 116 C171(0.74); C180(1.40)  LDD0777  [10]
 LDCM0461  CL69 HCT 116 C171(0.82); C180(1.16)  LDD0778  [10]
 LDCM0462  CL7 HCT 116 C171(0.91); C180(1.27)  LDD0779  [10]
 LDCM0463  CL70 HCT 116 C171(0.81); C180(1.36)  LDD0780  [10]
 LDCM0464  CL71 HCT 116 C171(0.81); C180(1.91)  LDD0781  [10]
 LDCM0465  CL72 HCT 116 C171(0.88); C180(1.19)  LDD0782  [10]
 LDCM0466  CL73 HCT 116 C171(0.73); C180(1.48)  LDD0783  [10]
 LDCM0467  CL74 HCT 116 C171(0.77); C180(1.41)  LDD0784  [10]
 LDCM0469  CL76 HCT 116 C171(0.70); C180(1.16)  LDD0786  [10]
 LDCM0470  CL77 HCT 116 C171(0.60); C180(1.45)  LDD0787  [10]
 LDCM0471  CL78 HCT 116 C171(0.82); C180(1.24)  LDD0788  [10]
 LDCM0472  CL79 HCT 116 C171(0.72); C180(1.36)  LDD0789  [10]
 LDCM0473  CL8 HCT 116 C171(0.97); C180(1.62)  LDD0790  [10]
 LDCM0474  CL80 HCT 116 C171(0.75); C180(1.07)  LDD0791  [10]
 LDCM0475  CL81 HCT 116 C171(0.78); C180(1.42)  LDD0792  [10]
 LDCM0476  CL82 HCT 116 C171(0.76); C180(1.67)  LDD0793  [10]
 LDCM0477  CL83 HCT 116 C171(0.67); C180(1.59)  LDD0794  [10]
 LDCM0478  CL84 HCT 116 C171(0.73); C180(2.07)  LDD0795  [10]
 LDCM0479  CL85 HCT 116 C171(0.69); C180(1.37)  LDD0796  [10]
 LDCM0480  CL86 HCT 116 C171(0.72); C180(1.23)  LDD0797  [10]
 LDCM0481  CL87 HCT 116 C171(0.66); C180(1.28)  LDD0798  [10]
 LDCM0482  CL88 HCT 116 C171(0.64); C180(1.55)  LDD0799  [10]
 LDCM0483  CL89 HCT 116 C171(0.86); C180(2.32)  LDD0800  [10]
 LDCM0484  CL9 HCT 116 C171(0.94); C180(1.27)  LDD0801  [10]
 LDCM0485  CL90 HCT 116 C171(0.60); C180(1.09)  LDD0802  [10]
 LDCM0486  CL91 HCT 116 C171(0.96); C180(1.10)  LDD0803  [10]
 LDCM0487  CL92 HCT 116 C171(0.95); C180(1.15)  LDD0804  [10]
 LDCM0488  CL93 HCT 116 C171(0.98); C180(1.11)  LDD0805  [10]
 LDCM0489  CL94 HCT 116 C171(0.86); C180(1.33)  LDD0806  [10]
 LDCM0490  CL95 HCT 116 C171(0.82); C180(1.42)  LDD0807  [10]
 LDCM0491  CL96 HCT 116 C171(0.82); C180(1.44)  LDD0808  [10]
 LDCM0492  CL97 HCT 116 C171(0.75); C180(1.81)  LDD0809  [10]
 LDCM0493  CL98 HCT 116 C171(0.94); C180(1.29)  LDD0810  [10]
 LDCM0494  CL99 HCT 116 C171(0.94); C180(1.11)  LDD0811  [10]
 LDCM0495  E2913 HEK-293T C180(0.91); C171(1.04)  LDD1698  [26]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C180(4.86)  LDD1702  [4]
 LDCM0573  Fragment11 Ramos C180(5.04)  LDD2190  [27]
 LDCM0576  Fragment14 Ramos C180(1.36)  LDD2193  [27]
 LDCM0586  Fragment28 Ramos C180(2.24)  LDD2198  [27]
 LDCM0468  Fragment33 HCT 116 C171(0.88); C180(1.25)  LDD0785  [10]
 LDCM0427  Fragment51 HCT 116 C171(0.91); C180(1.81)  LDD0744  [10]
 LDCM0615  Fragment63-R Jurkat _(19.98)  LDD1487  [6]
 LDCM0617  Fragment63-S Jurkat _(20.00)  LDD1490  [6]
 LDCM0569  Fragment7 Jurkat _(20.00)  LDD1485  [6]
 LDCM0116  HHS-0101 DM93 Y401(0.53)  LDD0264  [8]
 LDCM0117  HHS-0201 DM93 Y401(0.73)  LDD0265  [8]
 LDCM0118  HHS-0301 DM93 Y401(0.56)  LDD0266  [8]
 LDCM0119  HHS-0401 DM93 Y401(0.71)  LDD0267  [8]
 LDCM0120  HHS-0701 DM93 Y401(0.32)  LDD0268  [8]
 LDCM0022  KB02 HCT 116 C180(9.44)  LDD0080  [10]
 LDCM0023  KB03 HCT 116 C180(1.74)  LDD0081  [10]
 LDCM0024  KB05 HCT 116 C180(5.99)  LDD0082  [10]
 LDCM0109  NEM HeLa H500(0.00); H493(0.00)  LDD0223  [9]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C180(1.12)  LDD2090  [4]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C180(0.93)  LDD2093  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C180(0.97)  LDD2099  [4]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C180(0.64)  LDD2101  [4]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C180(1.05)  LDD2104  [4]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C180(1.09)  LDD2105  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C180(0.98)  LDD2107  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C180(0.94)  LDD2109  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C180(1.29)  LDD2111  [4]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C180(1.28)  LDD2115  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C180(2.50)  LDD2119  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C180(1.28)  LDD2123  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C180(1.12)  LDD2125  [4]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C180(0.97)  LDD2129  [4]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C180(0.59)  LDD2134  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C180(1.42)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C180(1.13)  LDD2137  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C180(0.75)  LDD2140  [4]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C180(0.76)  LDD2141  [4]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C180(2.18)  LDD2144  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C180(1.28)  LDD2146  [4]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C180(1.15)  LDD2153  [4]
 LDCM0628  OTUB2-COV-1 HEK-293T C180(1.00)  LDD2207  [28]
 LDCM0003  Sulforaphane MDA-MB-231 2.20  LDD0160  [5]
 LDCM0021  THZ1 HCT 116 C180(1.24); C171(0.84)  LDD2173  [10]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Maspardin (SPG21) AB hydrolase superfamily Q9NZD8
Anterior gradient protein 2 homolog (AGR2) AGR family O95994
Cell division cycle protein 23 homolog (CDC23) APC8/CDC23 family Q9UJX2
Histone-lysine N-methyltransferase SMYD3 (SMYD3) Histone-lysine methyltransferase family Q9H7B4
Eukaryotic translation initiation factor 3 subunit F (EIF3F) EIF-3 subunit F family O00303
Heme oxygenase 2 (HMOX2) Heme oxygenase family P30519
Caspase-6 (CASP6) Peptidase C14A family P55212
GTP-binding nuclear protein Ran (RAN) Ran family P62826
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Exocyst complex component 8 (EXOC8) EXO84 family Q8IYI6
Nuclear pore glycoprotein p62 (NUP62) Nucleoporin NSP1/NUP62 family P37198
Nucleoporin p58/p45 (NUP58) NUP58 family Q9BVL2
Exocyst complex component 1 (EXOC1) SEC3 family Q9NV70
Transcription factor
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
NF-kappa-B inhibitor delta (NFKBID) NF-kappa-B inhibitor family Q8NI38
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Homeobox protein PKNOX2 (PKNOX2) TALE/MEIS homeobox family Q96KN3
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 (SOHLH1) . Q5JUK2
Other
Click To Hide/Show 24 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
BPI fold-containing family A member 1 (BPIFA1) Plunc family Q9NP55
Centromere protein H (CENPH) CENP-H/MCM16 family Q9H3R5
Cholecystokinin (CCK) Gastrin/cholecystokinin family P06307
HAUS augmin-like complex subunit 1 (HAUS1) HAUS1 family Q96CS2
HAUS augmin-like complex subunit 8 (HAUS8) HAUS8 family Q9BT25
Homer protein homolog 1 (HOMER1) Homer family Q86YM7
Keratin, type I cuticular Ha3-II (KRT33B) Intermediate filament family Q14525
Keratin, type I cytoskeletal 15 (KRT15) Intermediate filament family P19012
Keratin, type I cytoskeletal 27 (KRT27) Intermediate filament family Q7Z3Y8
Protein Mis18-beta (OIP5) Mis18 family O43482
Transforming acidic coiled-coil-containing protein 3 (TACC3) TACC family Q9Y6A5
Trichoplein keratin filament-binding protein (TCHP) TCHP family Q9BT92
Tektin-1 (TEKT1) Tektin family Q969V4
Tropomyosin alpha-3 chain (TPM3) Tropomyosin family P06753
Vacuolar protein sorting-associated protein 37C (VPS37C) VPS37 family A5D8V6
AFG2-interacting ribosome maturation factor (AIRIM) . Q9NX04
EF-hand domain-containing protein 1 (EFHC1) . Q5JVL4
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964
Intraflagellar transport protein 20 homolog (IFT20) . Q8IY31
Nuclear transport factor 2 (NUTF2) . P61970
SERTA domain-containing protein 3 (SERTAD3) . Q9UJW9
Testis-expressed protein 12 (TEX12) . Q9BXU0
Uncharacterized protein C14orf119 (C14orf119) . Q9NWQ9
ZW10 interactor (ZWINT) . O95229

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane. Chem Commun (Camb). 2017 May 4;53(37):5182-5185. doi: 10.1039/c6cc08797c.
Mass spectrometry data entry: PXD006279
6 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
7 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
8 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
9 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
10 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
11 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
12 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
13 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
14 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
15 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
16 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
17 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
18 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
19 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
20 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
21 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
22 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
23 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
24 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
25 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
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Mass spectrometry data entry: PXD044402
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