Details of the Target

General Information of Target

Target ID LDTP17802
Target Name Glutathione S-transferase C-terminal domain-containing protein (GSTCD)
Gene Name GSTCD
Gene ID 79807
Synonyms
Glutathione S-transferase C-terminal domain-containing protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDKVQSGFLILFLFLMECQLHLCLPYADGLHPTGNITGLPGSKRSQPPRNITKEPKVFFH
KTQLPGIQGAASRSTAASPTNPMKFLRNKAIIRHRPALVKVILISSVAFSIALICGMAIS
YMIYRLAQAEERQQLESLYKNLRIPLLGDEEEGSEDEGESTHLLPENENELEKFIHSVII
SKRSKNIKKKLKEEQNSVTENKTKNASHNGKMEDL
Target Bioclass
Other
Family
GSTCD family
Subcellular location
Cytoplasm
Uniprot ID
Q8NEC7
Ensemble ID
ENST00000360505.9
HGNC ID
HGNC:25806

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL27 SNV: p.P441S .
CCK81 SNV: p.D66G DBIA    Probe Info 
HCC1806 SNV: p.D192H DBIA    Probe Info 
LS123 SNV: p.C41F DBIA    Probe Info 
MOLT4 SNV: p.G414C IA-alkyne    Probe Info 
SUPT1 SNV: p.M522V DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 15 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K133(10.00); K424(1.33)  LDD0277  [1]
Johansson_61
 Probe Info  		_(18.54)  LDD1485  [2]
BDBM50514113
 Probe Info  		11.56  LDD0041  [3]
DBIA
 Probe Info  		C140(1.00)  LDD0078  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		C150(0.00); C395(0.00)  LDD0038  [5]
IA-alkyne
 Probe Info  		C335(0.00); C395(0.00); C150(0.00)  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		C335(0.00); C395(0.00); C150(0.00); C140(0.00)  LDD0037  [5]
NAIA_4
 Probe Info  		N.A.  LDD2226  [6]
Compound 10
 Probe Info  		N.A.  LDD2216  [7]
Compound 11
 Probe Info  		N.A.  LDD2213  [7]
IPM
 Probe Info  		N.A.  LDD0005  [8]
NPM
 Probe Info  		N.A.  LDD0016  [8]
TFBX
 Probe Info  		N.A.  LDD0148  [9]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [10]
NAIA_5
 Probe Info  		C335(0.00); C150(0.00)  LDD2223  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C140(0.92); C539(0.86); C335(0.90)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C140(1.47); C335(0.61)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C140(0.91); C537(0.80); C539(0.85); C335(1.07)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C140(0.76); C537(0.77); C539(0.83); C335(0.93)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C140(0.91); C537(0.86); C539(0.95); C335(0.95)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C140(1.47); C537(0.84); C539(0.91); C335(0.95)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C140(1.09); C537(0.86); C539(0.94); C335(1.06)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C140(1.06); C537(0.88); C539(1.07); C335(0.99)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C140(1.23); C537(0.70); C539(0.70); C335(1.06)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C140(1.16); C537(0.76); C539(0.83); C335(1.00)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C140(1.08); C537(0.84); C539(0.88); C335(0.94)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C140(1.05); C537(1.09); C539(1.10); C335(1.14)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C140(1.83); C335(0.56)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C140(1.01); C537(0.78); C539(0.85); C335(0.90)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C140(0.89); C537(0.80); C539(0.81); C335(0.99)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C140(1.06); C537(0.83); C539(0.89); C335(0.94)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C537(0.87); C539(0.88); C540(0.88); C607(0.89)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C537(1.06); C539(1.13); C540(1.22); C607(0.92)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C537(1.09); C539(0.98); C540(1.21); C607(1.24)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C537(0.97); C539(0.97); C540(1.03); C607(0.99)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C537(0.80); C539(1.00); C540(1.17); C607(1.10)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C537(0.93); C539(1.16); C540(0.85); C607(0.90)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C537(1.03); C539(1.33); C540(0.95); C607(0.88)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C140(0.97); C335(0.75)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C537(0.97); C539(1.33); C540(1.24); C607(0.77)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C537(0.98); C539(1.27); C540(1.02); C607(1.06)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C537(0.88); C539(1.11); C540(0.96); C607(0.96)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C537(0.72); C539(1.05); C540(0.89); C607(0.65)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C537(0.75); C539(1.56); C540(1.28); C607(1.00)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C537(0.89); C539(1.27); C540(1.23); C607(0.93)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C537(1.07); C539(1.12); C540(1.02); C607(0.80)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C537(0.83); C539(1.17); C540(1.13); C607(0.87)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C537(1.38); C539(1.39); C335(0.56); C540(1.39)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C537(1.20); C539(0.98); C335(0.50); C540(0.98)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C537(1.13); C539(0.86); C335(0.50); C540(0.86)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C537(1.13); C539(1.07); C335(0.50); C540(1.07)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C537(1.14); C539(0.92); C335(0.61); C540(0.92)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C537(1.12); C539(0.92); C335(0.53); C540(0.92)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C537(1.17); C539(1.04); C335(0.53); C540(1.04)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C537(1.15); C539(1.14); C335(0.57); C540(1.14)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C537(1.06); C539(0.86); C335(0.52); C540(0.86)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C537(1.16); C539(1.10); C335(0.47); C540(1.10)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C537(1.10); C539(0.95); C335(0.50); C540(0.95)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C537(1.03); C539(0.94); C335(0.58); C540(0.94)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C140(0.89); C335(0.50)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C537(1.13); C539(1.01); C335(0.49); C540(1.01)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C537(1.21); C539(1.10); C335(0.54); C540(1.10)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C537(1.07); C539(0.95); C335(0.50); C540(0.95)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C140(0.80); C539(0.91); C335(1.04)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C140(0.49); C539(0.78); C335(0.90)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C140(0.93); C539(0.93); C335(1.22)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C140(0.75); C335(0.98); C539(1.30)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C140(0.53); C539(0.86); C335(1.00)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C539(0.63); C140(0.67); C335(0.93)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C539(0.72); C335(0.81); C140(0.87)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C335(0.59); C140(1.35)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C140(0.71); C539(0.77); C335(1.07)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C140(0.58); C539(0.84); C335(1.05)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C140(0.67); C539(0.85); C335(0.87)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C539(0.67); C140(0.74); C335(0.89)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C140(0.52); C539(0.93); C335(0.98)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C140(0.70); C539(0.78); C335(1.14)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C140(0.65); C539(0.87); C335(0.99)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C140(1.07); C539(1.07); C335(1.25)  LDD2161  [4]
 LDCM0276  AC17 HCT 116 C88(0.75); C89(0.75); C607(0.91); C621(0.91)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C88(0.40); C89(0.40); C335(0.94); C540(1.09)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C88(0.73); C89(0.73); C540(0.93); C335(1.14)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C335(0.83); C539(0.88); C140(0.97)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C88(0.74); C89(0.74); C540(0.91); C335(1.12)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C88(0.61); C89(0.61); C537(0.68); C539(0.68)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C88(0.83); C89(0.83); C335(0.86); C537(0.91)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C88(0.82); C89(0.82); C335(0.96); C540(1.05)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C88(0.90); C89(0.90); C140(1.02); C335(1.13)  LDD0601  [4]
 LDCM0285  AC25 HCT 116 C539(0.73); C140(0.99); C335(1.14)  LDD0602  [4]
 LDCM0286  AC26 HCT 116 C539(0.82); C335(0.87); C140(0.93)  LDD0603  [4]
 LDCM0287  AC27 HCT 116 C539(0.71); C335(0.94); C140(0.96)  LDD0604  [4]
 LDCM0288  AC28 HCT 116 C539(0.78); C140(0.86); C335(1.02)  LDD0605  [4]
 LDCM0289  AC29 HCT 116 C335(0.82); C140(0.88); C539(1.07)  LDD0606  [4]
 LDCM0290  AC3 HCT 116 C539(0.77); C335(0.81); C140(1.15)  LDD0607  [4]
 LDCM0291  AC30 HCT 116 C335(0.80); C140(0.84); C539(0.94)  LDD0608  [4]
 LDCM0292  AC31 HCT 116 C335(0.82); C140(0.90); C539(0.97)  LDD0609  [4]
 LDCM0293  AC32 HCT 116 C140(0.80); C335(0.85); C539(0.94)  LDD0610  [4]
 LDCM0294  AC33 HCT 116 C335(0.90); C140(0.92); C539(1.01)  LDD0611  [4]
 LDCM0295  AC34 HCT 116 C539(0.65); C140(0.82); C335(1.00)  LDD0612  [4]
 LDCM0296  AC35 HCT 116 C140(1.06); C335(1.13); C88(1.17); C89(1.17)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C140(0.78); C539(1.01); C335(1.03); C607(1.09)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C140(0.96); C607(0.96); C621(0.96); C335(0.99)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C140(1.00); C335(1.02); C88(1.04); C89(1.04)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C607(0.49); C621(0.49); C140(0.83); C539(1.02)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C539(0.89); C335(0.97); C140(1.12)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C607(0.57); C621(0.57); C335(0.90); C88(0.94)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C607(0.75); C621(0.75); C140(0.86); C335(0.87)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C607(0.73); C621(0.73); C335(1.22); C539(1.26)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C607(0.64); C621(0.64); C539(0.85); C335(0.87)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C607(0.62); C621(0.62); C335(0.94); C539(0.97)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C607(0.58); C621(0.58); C335(0.83); C140(0.95)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C88(0.89); C89(0.89); C540(0.92); C607(0.95)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C537(0.68); C539(0.68); C540(0.87); C88(0.92)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C607(0.57); C621(0.57); C537(0.61); C539(0.61)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C607(0.51); C621(0.51); C537(0.51); C539(0.51)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C140(0.92); C335(0.95); C539(0.97)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C537(0.60); C539(0.60); C540(0.79); C335(0.88)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C88(0.93); C89(0.93); C540(0.97); C140(1.13)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C607(0.77); C621(0.77); C88(0.87); C89(0.87)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C607(0.80); C621(0.80); C537(0.84); C539(0.84)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C537(0.75); C539(0.75); C607(0.77); C621(0.77)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C537(0.56); C539(0.56); C607(0.77); C621(0.77)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C607(0.66); C621(0.66); C540(0.73); C537(0.77)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C540(0.35); C537(0.55); C335(0.65); C539(0.70)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C540(0.33); C537(0.43); C335(0.68); C88(0.76)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C540(0.31); C537(0.41); C88(0.52); C89(0.52)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C335(0.68); C140(1.21)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C540(0.35); C335(0.55); C88(0.56); C89(0.56)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C540(0.32); C537(0.46); C335(0.60); C539(0.62)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C540(0.36); C537(0.50); C335(0.54); C88(0.60)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C540(0.37); C537(0.52); C335(0.55); C88(0.66)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C540(0.34); C537(0.44); C335(0.54); C539(0.65)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C540(0.35); C537(0.50); C335(0.59); C88(0.61)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C540(0.43); C537(0.60); C335(0.66); C539(0.80)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C540(0.26); C537(0.36); C335(0.44); C539(0.48)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C540(0.32); C537(0.40); C539(0.40); C335(0.80)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C537(0.35); C539(0.35); C540(0.37); C335(0.70)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C335(0.87); C140(4.01)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C540(0.19); C537(0.27); C539(0.27); C335(0.64)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C540(0.38); C537(0.62); C539(0.62); C140(0.86)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C540(0.39); C537(0.44); C539(0.44); C335(0.88)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C540(0.20); C537(0.23); C539(0.23); C335(0.67)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C540(0.23); C537(0.32); C539(0.32); C335(0.68)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C540(0.26); C537(0.29); C539(0.29); C335(0.73)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C540(0.27); C537(0.30); C539(0.30); C335(0.70)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C540(0.29); C537(0.34); C539(0.34); C335(0.65)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C540(0.29); C537(0.37); C539(0.37); C140(0.63)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C540(0.38); C537(0.52); C539(0.52); C88(0.86)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C335(0.65); C140(1.05)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C540(0.40); C537(0.42); C539(0.42); C140(0.65)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C540(0.55); C537(0.73); C539(0.73); C335(0.84)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C540(0.24); C537(0.31); C539(0.31); C88(0.82)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C537(0.38); C540(0.38); C607(0.41); C621(0.41)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C335(0.43); C607(0.45); C621(0.45); C537(0.47)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C607(0.50); C621(0.50); C537(0.56); C540(0.56)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C539(0.71); C537(0.76); C540(0.76); C607(0.83)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C539(0.82); C537(0.83); C540(0.83); C335(0.87)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C539(0.83); C537(0.84); C540(0.84); C335(0.88)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C539(0.60); C335(0.63); C537(0.65); C540(0.65)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C88(1.14); C89(1.14); C537(1.22); C540(1.22)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C335(0.46); C539(0.48); C537(0.56); C540(0.56)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C539(0.48); C537(0.49); C540(0.49); C335(0.51)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C335(0.73); C537(0.81); C540(0.81); C539(0.82)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C335(0.65); C539(0.88); C537(0.97); C540(0.97)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C539(0.49); C335(0.52); C537(0.52); C540(0.52)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C335(0.51); C539(0.65); C537(0.77); C540(0.77)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C539(0.50); C537(0.53); C540(0.53); C335(0.58)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C607(0.45); C621(0.45); C537(0.75); C539(0.76)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C607(0.47); C621(0.47); C537(0.70); C539(0.74)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C140(0.88); C335(0.78)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C335(0.68); C140(1.54)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C335(0.40); C140(1.55)  LDD0592  [4]
 LDCM0020  ARS-1620 HCC44 C140(1.00)  LDD0078  [4]
 LDCM0106  BDHI 18 Jurkat C140(6.59)  LDD0208  [11]
 LDCM0367  CL1 HCT 116 C607(0.95); C621(0.95); C88(0.97); C89(0.97)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C537(0.34); C540(0.34); C607(0.39); C621(0.39)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C335(0.84); C539(1.03); C140(1.09)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C335(0.67); C140(1.70)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C335(0.78); C140(4.87)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C335(0.77); C140(2.03)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C335(0.91); C140(4.93)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C88(0.57); C89(0.57); C540(0.91); C335(0.94)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C88(0.36); C89(0.36); C540(0.59); C537(1.01)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C88(0.50); C89(0.50); C540(0.72); C335(0.89)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C88(0.42); C89(0.42); C540(0.65); C335(1.12)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C88(0.73); C89(0.73); C540(0.84); C335(0.90)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C537(0.39); C540(0.39); C607(0.39); C621(0.39)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C88(0.56); C89(0.56); C540(0.70); C607(0.93)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C88(0.48); C89(0.48); C540(0.75); C537(0.78)  LDD0698  [4]
 LDCM0382  CL112 HCT 116 C335(1.07); C539(1.11); C140(1.83)  LDD0699  [4]
 LDCM0383  CL113 HCT 116 C140(0.87); C539(0.89); C335(0.89)  LDD0700  [4]
 LDCM0384  CL114 HCT 116 C539(0.87); C335(0.87); C140(1.39)  LDD0701  [4]
 LDCM0385  CL115 HCT 116 C335(0.85); C539(0.86); C140(1.08)  LDD0702  [4]
 LDCM0386  CL116 HCT 116 C539(0.74); C335(0.98); C140(1.09)  LDD0703  [4]
 LDCM0387  CL117 HCT 116 C607(0.42); C621(0.42); C88(0.67); C89(0.67)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C607(0.62); C621(0.62); C335(0.94); C539(1.06)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C539(0.84); C335(0.89); C607(0.97); C621(0.97)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C537(0.32); C540(0.32); C607(0.41); C621(0.41)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C607(0.83); C621(0.83); C539(0.98); C335(0.99)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C88(0.92); C89(0.92); C335(0.94); C540(1.12)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C607(0.61); C621(0.61); C537(0.74); C539(0.74)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C540(0.52); C537(0.58); C539(0.58); C607(0.68)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C537(0.50); C539(0.50); C607(0.57); C621(0.57)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C88(0.84); C89(0.84); C335(0.85); C607(0.89)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C88(0.72); C89(0.72); C607(0.83); C621(0.83)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C88(0.68); C89(0.68); C335(0.75); C607(0.80)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C540(0.33); C537(0.45); C335(0.68); C539(0.72)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C537(0.44); C540(0.44); C607(0.55); C621(0.55)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C537(0.54); C540(0.54); C539(0.74); C88(0.77)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C607(0.46); C621(0.46); C537(0.52); C540(0.52)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C335(0.77); C537(0.86); C539(0.90); C88(0.92)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C537(0.56); C539(0.65); C540(0.76); C335(0.87)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C537(0.30); C539(0.31); C540(0.44); C335(0.83)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C537(0.47); C539(0.48); C540(0.70); C335(0.93)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C607(0.81); C621(0.81); C88(0.88); C89(0.88)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C537(0.36); C539(0.37); C540(0.48); C335(0.84)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C537(0.40); C539(0.42); C540(0.54); C335(0.89)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C537(0.33); C539(0.36); C540(0.57); C335(0.86)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C537(0.48); C539(0.49); C540(0.62); C335(0.74)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C537(0.32); C539(0.34); C540(0.49); C335(0.68)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C140(3.46); C537(0.32); C539(0.32); C335(0.63)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C140(2.08); C537(0.52); C539(0.54); C335(0.58)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C140(2.09); C537(0.48); C539(0.51); C335(0.73)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C140(3.37); C537(0.42); C539(0.43); C335(0.65)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C140(1.16); C537(0.37); C539(0.39); C335(0.66)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C140(1.13); C537(0.76); C539(0.73); C540(0.76)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C140(1.54); C537(0.64); C539(0.64); C335(0.68)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C537(1.00); C539(1.15); C335(1.26); C540(1.00)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C537(0.50); C539(0.56); C335(0.95); C540(0.50)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C537(0.43); C539(0.58); C335(0.81); C540(0.43)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C537(0.56); C539(0.55); C335(0.89); C540(0.56)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C537(0.45); C539(0.53); C335(0.83); C540(0.45)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C537(0.41); C539(0.56); C335(1.21); C540(0.41)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C537(0.33); C539(0.46); C335(0.97); C540(0.33)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C537(0.50); C539(0.57); C335(1.09); C540(0.50)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C140(1.13); C537(0.80); C539(0.81); C540(0.80)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C537(0.48); C539(0.58); C335(0.98); C540(0.48)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C537(0.47); C539(0.59); C335(1.05); C540(0.47)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C537(0.47); C539(0.61); C335(1.18); C540(0.47)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C537(0.41); C539(0.52); C335(1.14); C540(0.41)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C537(0.43); C539(0.56); C335(0.93); C540(0.43)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C537(0.41); C539(0.47); C335(0.87); C540(0.41)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C140(12.04); C539(0.67); C335(0.85); C88(1.51)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C140(2.71); C539(0.87); C335(0.92); C88(1.37)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C140(14.19); C539(1.09); C335(0.77); C88(1.61)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C140(1.59); C539(0.93); C335(0.95); C88(1.30)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C140(1.49); C537(0.50); C539(0.63); C540(0.50)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C140(20.00); C539(0.95); C335(0.86); C88(1.40)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C140(8.30); C539(0.85); C335(0.98); C88(1.45)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C140(2.65); C539(0.93); C335(0.85); C88(1.75)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C140(11.47); C539(1.33); C335(0.98); C88(1.49)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C140(10.37); C539(0.90); C335(0.84); C88(0.94)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C140(1.20); C539(0.86); C335(1.01); C88(1.60)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C140(3.43); C539(1.09); C335(1.04); C88(1.20)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C140(10.33); C539(1.19); C335(1.02); C88(1.24)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C140(1.05); C539(0.69); C335(1.00); C88(1.44)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C140(2.03); C539(1.10); C335(1.01); C88(1.20)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C140(1.38); C537(0.49); C539(0.58); C540(0.49)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C140(13.01); C539(0.99); C335(0.83); C88(1.14)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C140(2.01); C539(0.91); C88(0.72); C89(0.72)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C140(2.39); C539(0.65); C88(0.71); C89(0.71)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C140(3.00); C539(0.66); C88(0.69); C89(0.69)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C140(3.56); C539(0.80); C88(0.83); C89(0.83)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C140(1.64); C539(0.90); C88(0.84); C89(0.84)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C140(3.21); C539(0.43); C88(0.44); C89(0.44)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C140(1.30); C539(0.58); C88(0.53); C89(0.53)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C140(1.67); C539(0.71); C88(0.51); C89(0.51)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C140(3.35); C539(0.59); C88(0.42); C89(0.42)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C140(1.87); C537(0.41); C539(0.59); C540(0.41)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C140(1.39); C539(0.61); C88(0.50); C89(0.50)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C140(3.69); C539(0.68); C88(0.64); C89(0.64)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C140(1.84); C539(0.80); C88(0.99); C89(0.99)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C140(3.17); C539(0.66); C88(0.50); C89(0.50)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C140(3.93); C539(0.82); C88(0.62); C89(0.62)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C140(1.62); C537(0.68); C539(0.70); C540(0.81)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C140(5.99); C537(1.01); C539(1.34); C540(0.91)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C140(1.86); C537(0.66); C539(0.73); C540(0.62)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C140(1.53); C537(0.47); C539(0.57); C540(0.42)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C140(1.13); C537(0.33); C539(0.52); C540(0.33)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C140(1.06); C537(0.77); C539(0.78); C540(0.77)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C140(3.39); C537(0.68); C539(0.82); C540(0.74)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C140(1.80); C537(0.35); C539(0.57); C540(0.35)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C140(6.37); C537(0.39); C539(0.59); C540(0.40)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C140(10.90); C537(0.41); C539(0.52); C540(0.43)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C140(6.01); C537(0.90); C539(0.96); C540(0.82)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C140(2.23); C537(0.94); C539(0.98); C540(1.00)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C140(5.02); C537(0.60); C539(0.74); C540(0.59)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C140(1.21); C537(0.41); C539(0.50); C540(0.35)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C140(1.69); C537(0.41); C539(0.55); C540(0.37)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C140(1.20); C537(0.51); C539(0.65); C540(0.51)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C140(6.11); C537(0.96); C539(1.04); C540(1.01)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C140(1.03); C539(0.75); C335(0.96)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C140(2.07); C539(0.93); C335(0.99)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C140(1.07); C539(0.84); C335(1.16)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C140(4.78); C539(1.02); C335(1.08)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C140(2.67); C539(0.84); C335(1.05)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C140(1.99); C539(0.72); C335(0.84)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C140(3.11); C539(0.67); C335(0.82)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C140(1.04); C539(1.19); C335(0.81)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C140(1.01); C539(0.86); C335(0.86)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C571(1.14); C140(2.25); C357(1.14); C335(1.17)  LDD1698  [12]
 LDCM0201  EV-3 T cell C140(10.29)  LDD0515  [13]
 LDCM0202  EV-93 T cell C140(4.55)  LDD0514  [13]
 LDCM0625  F8 Ramos C357(0.68)  LDD2187  [14]
 LDCM0572  Fragment10 Ramos C335(0.29)  LDD2189  [14]
 LDCM0573  Fragment11 Ramos C335(0.13)  LDD2190  [14]
 LDCM0575  Fragment13 MDA-MB-231 C140(1.77)  LDD1469  [2]
 LDCM0576  Fragment14 Ramos C140(0.73); C357(0.81)  LDD2193  [14]
 LDCM0580  Fragment21 Ramos C335(0.46)  LDD2195  [14]
 LDCM0582  Fragment23 Ramos C335(0.85)  LDD2196  [14]
 LDCM0578  Fragment27 Ramos C140(1.89); C335(0.82)  LDD2197  [14]
 LDCM0586  Fragment28 Ramos C357(1.26)  LDD2198  [14]
 LDCM0588  Fragment30 Ramos C335(0.75)  LDD2199  [14]
 LDCM0589  Fragment31 Ramos C140(0.99); C335(1.27)  LDD2200  [14]
 LDCM0590  Fragment32 Ramos C335(0.44)  LDD2201  [14]
 LDCM0468  Fragment33 HCT 116 C140(3.91); C539(0.76); C88(0.69); C89(0.69)  LDD0785  [4]
 LDCM0596  Fragment38 Ramos C140(1.15); C335(3.32)  LDD2203  [14]
 LDCM0566  Fragment4 Ramos C335(0.55); C357(0.62)  LDD2184  [14]
 LDCM0603  Fragment45 MDA-MB-231 C140(20.00)  LDD1482  [2]
 LDCM0427  Fragment51 HCT 116 C537(0.49); C539(0.54); C335(1.19); C540(0.49)  LDD0744  [4]
 LDCM0610  Fragment52 Ramos C140(1.27); C335(0.57)  LDD2204  [14]
 LDCM0614  Fragment56 Ramos C140(2.78)  LDD2205  [14]
 LDCM0615  Fragment63-R Jurkat _(20.00)  LDD1487  [2]
 LDCM0617  Fragment63-S Jurkat _(20.00)  LDD1490  [2]
 LDCM0569  Fragment7 Jurkat _(18.54)  LDD1485  [2]
 LDCM0022  KB02 HCT 116 C140(20.00); C607(1.80); C621(1.80); C539(1.76)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C140(20.00); C607(0.93); C621(0.93); C539(0.68)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C140(20.00); C607(0.83); C621(0.83); C539(0.65)  LDD0082  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C140(0.07)  LDD2206  [15]
 LDCM0628  OTUB2-COV-1 HEK-293T C140(0.73)  LDD2207  [15]
 LDCM0131  RA190 MM1.R C140(1.37)  LDD0304  [16]
 LDCM0021  THZ1 HCT 116 C140(1.29)  LDD2173  [4]
 LDCM0002  Ward_cp1 U2OS 11.56  LDD0041  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein arginine N-methyltransferase 6 (PRMT6) Protein arginine N-methyltransferase family Q96LA8
Lysine-specific histone demethylase 1A (KDM1A) Flavin monoamine oxidase family O60341

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
3 Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells. ACS Chem Biol. 2016 Dec 16;11(12):3268-3272. doi: 10.1021/acschembio.6b00766. Epub 2016 Oct 31.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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