Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | IA-alkyne | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 100 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
TMT
|
|||||
| Competitor Name | EV-3 | Competitor Info | ||||
| Competitor Concentration | 10 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cell lysate (T cell) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP12428 | Omega-amidase NIT2 (NIT2) | C153 | 20.0 | |||
| LDTP09598 | Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) | C207 | 12.4 | |||
| LDTP05822 | Serine-protein kinase ATM (ATM) | C1396 | 8.9 | |||
| LDTP12040 | Prostaglandin E synthase 2 (PTGES2) | C110 | 8.5 | |||
| LDTP14159 | Ubiquitin carboxyl-terminal hydrolase 16 (USP16) | C205 | 8.5 | |||
| LDTP12386 | Polyamine-transporting ATPase 13A2 (ATP13A2) | C365 | 8.5 | |||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | C282 | 7.8 | |||
| LDTP09344 | Prostamide/prostaglandin F synthase (PRXL2B) | C44 | 6.5 | |||
| LDTP02852 | Methylated-DNA--protein-cysteine methyltransferase (MGMT) | C145 | 6.4 | |||
| LDTP12784 | Pyroglutamyl-peptidase 1 (PGPEP1) | C149 | 6.3 | |||
| LDTP01707 | Thioredoxin domain-containing protein 12 (TXNDC12) | C66 | 6.0 | |||
| LDTP05128 | Glutathione S-transferase omega-1 (GSTO1) | C32 | 5.8 | |||
| LDTP17247 | 5'-nucleotidase domain-containing protein 1 (NT5DC1) | C119 | 5.3 | |||
| LDTP13302 | Nuclear prelamin A recognition factor (NARF) | C99 | 5.2 | |||
| LDTP06900 | Protein mono-ADP-ribosyltransferase PARP10 (PARP10) | C981 | 5.2 | |||
| LDTP05892 | Baculoviral IAP repeat-containing protein 3 (BIRC3) | C28 | 5.2 | |||
| LDTP09391 | Ceramide kinase (CERK) | C400 | 5.1 | |||
| LDTP03497 | Non-receptor tyrosine-protein kinase TYK2 (TYK2) | C838 | 5.0 | |||
| LDTP08619 | Probable ATP-dependent RNA helicase DDX60 (DDX60) | C517 | 4.7 | |||
| LDTP03458 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) | C287 | 4.6 | |||
| LDTP06720 | Peroxisomal leader peptide-processing protease (TYSND1) | C284 | 4.5 | |||
| LDTP03163 | Sterol carrier protein 2 (SCP2) | C71 | 4.4 | |||
| LDTP15311 | Deaminated glutathione amidase (NIT1) | C203 | 4.0 | |||
Transporter and channel
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP07793 | Beclin 1-associated autophagy-related key regulator (ATG14) | C330 | 5.5 | |||
Immunoglobulin
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP02338 | CD48 antigen (CD48) | C193, C196 | 6.3 | |||
Other
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP17802 | Glutathione S-transferase C-terminal domain-containing protein (GSTCD) | C140 | 10.3 | |||
| LDTP13515 | Zinc finger protein 346 (ZNF346) | C68 | 6.9 | |||
| LDTP13906 | Polymerase delta-interacting protein 2 (POLDIP2) | C143 | 5.3 | |||