General Information of Experiment

Probe Name Johansson_61  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Fragment63-S  Competitor Info 
Competitor Concentration 7.5 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Bone marrow
Disease Model T acute lymphoblastic leukemia [ICD-11:2A90]
Model Name Human T acute lymphoblastic leukemia cell lysate (Jurkat)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 9 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP17247  5'-nucleotidase domain-containing protein 1 (NT5DC1) 20.0
 LDTP01459  ABC-type organic anion transporter ABCA8 (ABCA8) 20.0
 LDTP01825  GTPase NRas (NRAS) 20.0
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 20.0
 LDTP04988  Thioredoxin reductase-like selenoprotein T (SELENOT) 20.0
 LDTP09749  Titin (TTN) 20.0
 LDTP03831  Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4) 7.4
 LDTP11294  Protein adenylyltransferase SelO, mitochondrial (SELENOO) 6.5
 LDTP03163  Sterol carrier protein 2 (SCP2) 4.5
Other
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11068  Cytochrome b-245 chaperone 1 (CYBC1) 20.0
 LDTP02077  Integrin beta-2 (ITGB2) 20.0
 LDTP02031  Keratin, type II cytoskeletal 1 (KRT1) 20.0
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 20.0
 LDTP11890  Protein unc-45 homolog A (UNC45A) 20.0
 LDTP06397  SCL-interrupting locus protein (STIL) 20.0
 LDTP17802  Glutathione S-transferase C-terminal domain-containing protein (GSTCD) 15.0
 LDTP02674  Keratin, type I cytoskeletal 10 (KRT10) 10.0

References

1 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.