Details of the Target

General Information of Target

Target ID LDTP19672
Target Name Selenoprotein H (SELENOH)
Gene Name SELENOH
Gene ID 280636
Synonyms
C11orf31; SELH; Selenoprotein H; SelH
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAPPSPGRTADQADQVCTFLFKKPGRKGAAGLRKRPACDPEHGESSSSGDEGDTVAQPP
RVAPRPRGLHSWQKAAHGDRRGEEAAPESLDVVYRSTRSAKPVGPEDMGATADFEQDTEK
EHHTPTILKCSQRVQEALRGREHDHIYRGIHSYLRYLKPKDTSMGNSSSGMARKGPIRAP
GHLRATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDYKLGWEIERELEEGRYCICED
ENHEVGSEEEEIPFRCFICRQAFQNPVVTKCRHYFCESCALEHFRATPRCYICDQPTGGI
FNPAKELMAKLQKLQAAEGKKR
Target Bioclass
Other
Family
SelWTH family
Function May be involved in a redox-related process.
Uniprot ID
Q8IZQ5
Ensemble ID
ENST00000388857.8
HGNC ID
HGNC:18251

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Johansson_61
 Probe Info  		_(11.82)  LDD1485  [1]
YY4-yne
 Probe Info  		2.20  LDD0400  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0615  Fragment63-R Jurkat _(20.00)  LDD1487  [1]
 LDCM0569  Fragment7 Jurkat _(11.82)  LDD1485  [1]
 LDCM0154  YY4 T cell 2.20  LDD0400  [2]

References

1 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
2 A Chemical Proteomic Probe for the Mitochondrial Pyruvate Carrier Complex. Angew Chem Int Ed Engl. 2020 Mar 2;59(10):3896-3899. doi: 10.1002/anie.201914391. Epub 2020 Feb 11.