Details of the Target

General Information of Target

Target ID LDTP19476
Target Name AMMECR1-like protein (AMMECR1L)
Gene Name AMMECR1L
Gene ID 83607
Synonyms
AMMECR1-like protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVPRISAAIFIFELLGSNSEGVTDLRLWLCQPAPRCGEWTYNPLEQCCDDGVILDLNQTR
LCGSSCTFWPCFQHCCLESLGSQNQTVVRFKVPGMKPDCKSSPITRICAQEYHPKSPVSR
SDLI
Target Bioclass
Other
Uniprot ID
Q6DCA0
Ensemble ID
ENST00000272647.10
HGNC ID
HGNC:28658

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
Johansson_61
 Probe Info  		_(20.00)  LDD1485  [2]
AHL-Pu-1
 Probe Info  		C153(2.38)  LDD0170  [3]
DBIA
 Probe Info  		C153(21.96)  LDD0209  [4]
BDBM50514113
 Probe Info  		2.93  LDD0041  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [6]
IPM
 Probe Info  		N.A.  LDD0025  [7]
Compound 10
 Probe Info  		N.A.  LDD2216  [8]
Compound 11
 Probe Info  		N.A.  LDD2213  [8]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [9]
AOyne
 Probe Info  		15.00  LDD0443  [10]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C153(2.38)  LDD0170  [3]
 LDCM0026  4SU-RNA+native RNA DM93 C153(2.23)  LDD0171  [3]
 LDCM0214  AC1 HCT 116 C18(0.95); C19(0.95)  LDD0531  [11]
 LDCM0215  AC10 HCT 116 C153(0.81); C18(0.85); C19(0.85)  LDD0532  [11]
 LDCM0216  AC100 HCT 116 C153(1.32); C18(0.99); C19(0.99)  LDD0533  [11]
 LDCM0217  AC101 HCT 116 C153(1.58); C18(0.78); C19(0.78)  LDD0534  [11]
 LDCM0218  AC102 HCT 116 C153(1.45); C18(0.85); C19(0.85)  LDD0535  [11]
 LDCM0219  AC103 HCT 116 C153(2.06); C18(1.36); C19(1.36)  LDD0536  [11]
 LDCM0220  AC104 HCT 116 C153(0.86); C18(1.19); C19(1.19)  LDD0537  [11]
 LDCM0221  AC105 HCT 116 C153(1.60); C18(0.80); C19(0.80)  LDD0538  [11]
 LDCM0222  AC106 HCT 116 C153(1.83); C18(0.92); C19(0.92)  LDD0539  [11]
 LDCM0223  AC107 HCT 116 C153(1.21); C18(0.78); C19(0.96)  LDD0540  [11]
 LDCM0224  AC108 HCT 116 C153(1.14); C18(0.85); C19(0.85)  LDD0541  [11]
 LDCM0225  AC109 HCT 116 C153(1.18); C18(0.71); C19(0.73)  LDD0542  [11]
 LDCM0226  AC11 HCT 116 C153(0.81); C18(0.83); C19(0.83)  LDD0543  [11]
 LDCM0227  AC110 HCT 116 C153(1.60); C18(0.91); C19(0.89)  LDD0544  [11]
 LDCM0228  AC111 HCT 116 C153(1.39); C18(1.17); C19(1.18)  LDD0545  [11]
 LDCM0229  AC112 HCT 116 C153(1.34); C18(0.98); C19(1.09)  LDD0546  [11]
 LDCM0230  AC113 HCT 116 C153(0.95); C18(0.96); C19(0.96)  LDD0547  [11]
 LDCM0231  AC114 HCT 116 C153(0.99); C18(1.11); C19(1.11)  LDD0548  [11]
 LDCM0232  AC115 HCT 116 C153(0.95); C18(0.95); C19(0.95)  LDD0549  [11]
 LDCM0233  AC116 HCT 116 C153(1.08); C18(1.11); C19(1.11)  LDD0550  [11]
 LDCM0234  AC117 HCT 116 C153(0.99); C18(0.95); C19(0.95)  LDD0551  [11]
 LDCM0235  AC118 HCT 116 C153(1.02); C18(0.92); C19(0.92)  LDD0552  [11]
 LDCM0236  AC119 HCT 116 C153(1.06); C18(1.14); C19(1.14)  LDD0553  [11]
 LDCM0237  AC12 HCT 116 C153(0.84); C18(0.84); C19(0.84)  LDD0554  [11]
 LDCM0238  AC120 HCT 116 C153(1.01); C18(0.98); C19(0.98)  LDD0555  [11]
 LDCM0239  AC121 HCT 116 C153(0.96); C18(0.85); C19(0.85)  LDD0556  [11]
 LDCM0240  AC122 HCT 116 C153(1.01); C18(1.00); C19(1.00)  LDD0557  [11]
 LDCM0241  AC123 HCT 116 C153(0.86); C18(0.86); C19(0.86)  LDD0558  [11]
 LDCM0242  AC124 HCT 116 C153(1.04); C18(0.93); C19(0.93)  LDD0559  [11]
 LDCM0243  AC125 HCT 116 C153(1.02); C18(0.98); C19(0.98)  LDD0560  [11]
 LDCM0244  AC126 HCT 116 C153(1.09); C18(0.97); C19(0.97)  LDD0561  [11]
 LDCM0245  AC127 HCT 116 C153(0.91); C18(1.09); C19(1.09)  LDD0562  [11]
 LDCM0246  AC128 HCT 116 C153(1.34)  LDD0563  [11]
 LDCM0247  AC129 HCT 116 C153(1.32)  LDD0564  [11]
 LDCM0249  AC130 HCT 116 C153(1.06)  LDD0566  [11]
 LDCM0250  AC131 HCT 116 C153(1.19)  LDD0567  [11]
 LDCM0251  AC132 HCT 116 C153(1.44)  LDD0568  [11]
 LDCM0252  AC133 HCT 116 C153(1.30)  LDD0569  [11]
 LDCM0253  AC134 HCT 116 C153(1.38)  LDD0570  [11]
 LDCM0254  AC135 HCT 116 C153(1.19)  LDD0571  [11]
 LDCM0255  AC136 HCT 116 C153(1.35)  LDD0572  [11]
 LDCM0256  AC137 HCT 116 C153(1.32)  LDD0573  [11]
 LDCM0257  AC138 HCT 116 C153(1.67)  LDD0574  [11]
 LDCM0258  AC139 HCT 116 C153(1.31)  LDD0575  [11]
 LDCM0259  AC14 HCT 116 C153(0.84); C18(0.85); C19(0.85)  LDD0576  [11]
 LDCM0260  AC140 HCT 116 C153(1.40)  LDD0577  [11]
 LDCM0261  AC141 HCT 116 C153(1.34)  LDD0578  [11]
 LDCM0262  AC142 HCT 116 C153(1.25)  LDD0579  [11]
 LDCM0263  AC143 HCT 116 C153(0.92); C18(0.85); C19(0.85)  LDD0580  [11]
 LDCM0264  AC144 HCT 116 C18(0.85); C19(0.85); C153(1.20)  LDD0581  [11]
 LDCM0265  AC145 HCT 116 C18(0.70); C19(0.70); C153(0.95)  LDD0582  [11]
 LDCM0266  AC146 HCT 116 C18(0.79); C19(0.79); C153(1.36)  LDD0583  [11]
 LDCM0267  AC147 HCT 116 C18(0.72); C19(0.72); C153(1.28)  LDD0584  [11]
 LDCM0268  AC148 HCT 116 C18(1.00); C19(1.00); C153(1.53)  LDD0585  [11]
 LDCM0269  AC149 HCT 116 C18(1.11); C19(1.11); C153(1.26)  LDD0586  [11]
 LDCM0270  AC15 HCT 116 C18(0.65); C19(0.65); C153(1.02)  LDD0587  [11]
 LDCM0271  AC150 HCT 116 C18(0.58); C19(0.58); C153(1.13)  LDD0588  [11]
 LDCM0272  AC151 HCT 116 C18(0.74); C19(0.74); C153(1.02)  LDD0589  [11]
 LDCM0273  AC152 HCT 116 C18(0.62); C19(0.62); C153(1.70)  LDD0590  [11]
 LDCM0274  AC153 HCT 116 C18(0.63); C19(0.63); C153(1.75)  LDD0591  [11]
 LDCM0621  AC154 HCT 116 C153(1.00); C18(0.63); C19(0.63)  LDD2158  [11]
 LDCM0622  AC155 HCT 116 C153(0.97); C18(0.59); C19(0.59)  LDD2159  [11]
 LDCM0623  AC156 HCT 116 C153(1.04); C18(0.69); C19(0.69)  LDD2160  [11]
 LDCM0624  AC157 HCT 116 C153(1.33); C18(0.60); C19(0.60)  LDD2161  [11]
 LDCM0276  AC17 HCT 116 C153(0.69); C18(0.73); C19(0.73)  LDD0593  [11]
 LDCM0277  AC18 HCT 116 C153(0.82); C18(0.86); C19(0.86)  LDD0594  [11]
 LDCM0278  AC19 HCT 116 C18(0.68); C19(0.68); C153(0.70)  LDD0595  [11]
 LDCM0279  AC2 HCT 116 C18(0.86); C19(0.86)  LDD0596  [11]
 LDCM0280  AC20 HCT 116 C18(0.72); C19(0.72); C153(1.07)  LDD0597  [11]
 LDCM0281  AC21 HCT 116 C153(0.72); C18(0.74); C19(0.74)  LDD0598  [11]
 LDCM0282  AC22 HCT 116 C18(0.73); C19(0.73); C153(0.78)  LDD0599  [11]
 LDCM0283  AC23 HCT 116 C18(0.66); C19(0.66); C153(2.33)  LDD0600  [11]
 LDCM0284  AC24 HCT 116 C18(0.60); C19(0.60); C153(0.80)  LDD0601  [11]
 LDCM0285  AC25 HEK-293T C6(0.98); C153(1.18)  LDD1524  [12]
 LDCM0286  AC26 HEK-293T C6(1.00); C294(0.89)  LDD1525  [12]
 LDCM0287  AC27 HEK-293T C6(1.09); C153(1.08); C294(1.18); C18(1.03)  LDD1526  [12]
 LDCM0288  AC28 HEK-293T C6(1.10); C153(1.10); C294(1.03)  LDD1527  [12]
 LDCM0289  AC29 HEK-293T C6(0.97); C294(0.93)  LDD1528  [12]
 LDCM0290  AC3 HCT 116 C18(0.83); C19(0.83)  LDD0607  [11]
 LDCM0291  AC30 HEK-293T C6(1.01); C153(1.10)  LDD1530  [12]
 LDCM0292  AC31 HEK-293T C6(1.08); C153(1.06); C19(1.03)  LDD1531  [12]
 LDCM0293  AC32 HEK-293T C6(0.92); C153(0.80)  LDD1532  [12]
 LDCM0294  AC33 HEK-293T C6(0.95); C153(0.98)  LDD1533  [12]
 LDCM0295  AC34 HEK-293T C6(0.97); C294(0.89)  LDD1534  [12]
 LDCM0296  AC35 HCT 116 C153(0.79)  LDD0613  [11]
 LDCM0297  AC36 HCT 116 C153(1.24)  LDD0614  [11]
 LDCM0298  AC37 HCT 116 C153(1.63)  LDD0615  [11]
 LDCM0299  AC38 HCT 116 C153(0.90)  LDD0616  [11]
 LDCM0300  AC39 HCT 116 C153(1.04)  LDD0617  [11]
 LDCM0301  AC4 HCT 116 C18(0.80); C19(0.80)  LDD0618  [11]
 LDCM0302  AC40 HCT 116 C153(1.19)  LDD0619  [11]
 LDCM0303  AC41 HCT 116 C153(0.90)  LDD0620  [11]
 LDCM0304  AC42 HCT 116 C153(0.96)  LDD0621  [11]
 LDCM0305  AC43 HCT 116 C153(0.97)  LDD0622  [11]
 LDCM0306  AC44 HCT 116 C153(0.93)  LDD0623  [11]
 LDCM0307  AC45 HCT 116 C153(0.99)  LDD0624  [11]
 LDCM0308  AC46 HCT 116 C153(1.16)  LDD0625  [11]
 LDCM0309  AC47 HCT 116 C153(1.25)  LDD0626  [11]
 LDCM0310  AC48 HCT 116 C153(1.15)  LDD0627  [11]
 LDCM0311  AC49 HCT 116 C153(1.18)  LDD0628  [11]
 LDCM0312  AC5 HCT 116 C18(0.83); C19(0.83)  LDD0629  [11]
 LDCM0313  AC50 HCT 116 C153(1.32)  LDD0630  [11]
 LDCM0314  AC51 HCT 116 C153(0.96)  LDD0631  [11]
 LDCM0315  AC52 HCT 116 C153(1.10)  LDD0632  [11]
 LDCM0316  AC53 HCT 116 C153(1.28)  LDD0633  [11]
 LDCM0317  AC54 HCT 116 C153(1.05)  LDD0634  [11]
 LDCM0318  AC55 HCT 116 C153(1.16)  LDD0635  [11]
 LDCM0319  AC56 HCT 116 C153(1.13)  LDD0636  [11]
 LDCM0320  AC57 HCT 116 C18(0.64); C19(0.64)  LDD0637  [11]
 LDCM0321  AC58 HCT 116 C18(0.79); C19(0.79)  LDD0638  [11]
 LDCM0322  AC59 HCT 116 C18(0.75); C19(0.75)  LDD0639  [11]
 LDCM0323  AC6 HCT 116 C18(0.82); C19(0.82); C153(1.17)  LDD0640  [11]
 LDCM0324  AC60 HCT 116 C18(0.68); C19(0.68)  LDD0641  [11]
 LDCM0325  AC61 HCT 116 C18(0.53); C19(0.53)  LDD0642  [11]
 LDCM0326  AC62 HCT 116 C18(0.67); C19(0.67)  LDD0643  [11]
 LDCM0327  AC63 HCT 116 C18(0.73); C19(0.73)  LDD0644  [11]
 LDCM0328  AC64 HCT 116 C18(0.61); C19(0.61)  LDD0645  [11]
 LDCM0329  AC65 HCT 116 C18(0.31); C19(0.31)  LDD0646  [11]
 LDCM0330  AC66 HCT 116 C18(0.30); C19(0.30)  LDD0647  [11]
 LDCM0331  AC67 HCT 116 C18(0.32); C19(0.32)  LDD0648  [11]
 LDCM0332  AC68 HCT 116 C18(0.86); C19(0.86); C153(1.07)  LDD0649  [11]
 LDCM0333  AC69 HCT 116 C153(1.01); C18(1.03); C19(1.03)  LDD0650  [11]
 LDCM0334  AC7 HCT 116 C18(0.81); C19(0.81); C153(0.94)  LDD0651  [11]
 LDCM0335  AC70 HCT 116 C18(1.35); C19(1.35); C153(1.37)  LDD0652  [11]
 LDCM0336  AC71 HCT 116 C18(0.85); C19(0.85); C153(1.09)  LDD0653  [11]
 LDCM0337  AC72 HCT 116 C153(1.14); C18(1.14); C19(1.14)  LDD0654  [11]
 LDCM0338  AC73 HCT 116 C18(1.20); C19(1.20); C153(1.47)  LDD0655  [11]
 LDCM0339  AC74 HCT 116 C18(1.12); C19(1.12); C153(1.55)  LDD0656  [11]
 LDCM0340  AC75 HCT 116 C153(1.40); C18(1.45); C19(1.45)  LDD0657  [11]
 LDCM0341  AC76 HCT 116 C18(1.00); C19(1.00); C153(1.16)  LDD0658  [11]
 LDCM0342  AC77 HCT 116 C18(1.08); C19(1.08); C153(1.25)  LDD0659  [11]
 LDCM0343  AC78 HCT 116 C18(1.04); C19(1.04); C153(1.14)  LDD0660  [11]
 LDCM0344  AC79 HCT 116 C18(0.98); C19(0.98); C153(1.19)  LDD0661  [11]
 LDCM0345  AC8 HCT 116 C18(0.82); C19(0.82); C153(0.86)  LDD0662  [11]
 LDCM0346  AC80 HCT 116 C153(1.01); C18(1.12); C19(1.12)  LDD0663  [11]
 LDCM0347  AC81 HCT 116 C153(1.15); C18(1.18); C19(1.18)  LDD0664  [11]
 LDCM0348  AC82 HCT 116 C153(1.44); C18(1.49); C19(1.49)  LDD0665  [11]
 LDCM0349  AC83 HCT 116 C153(1.07); C18(1.40); C19(1.40)  LDD0666  [11]
 LDCM0350  AC84 HCT 116 C153(1.08); C18(1.26); C19(1.26)  LDD0667  [11]
 LDCM0351  AC85 HCT 116 C153(0.76); C18(1.04); C19(1.04)  LDD0668  [11]
 LDCM0352  AC86 HCT 116 C153(0.83); C18(1.18); C19(1.18)  LDD0669  [11]
 LDCM0353  AC87 HCT 116 C153(0.73); C18(1.23); C19(1.23)  LDD0670  [11]
 LDCM0354  AC88 HCT 116 C153(0.86); C18(1.38); C19(1.38)  LDD0671  [11]
 LDCM0355  AC89 HCT 116 C153(0.81); C18(1.38); C19(1.38)  LDD0672  [11]
 LDCM0357  AC90 HCT 116 C153(0.60); C18(1.21); C19(1.21)  LDD0674  [11]
 LDCM0358  AC91 HCT 116 C153(0.90); C18(1.48); C19(1.48)  LDD0675  [11]
 LDCM0359  AC92 HCT 116 C153(0.75); C18(1.45); C19(1.45)  LDD0676  [11]
 LDCM0360  AC93 HCT 116 C153(0.70); C18(1.38); C19(1.38)  LDD0677  [11]
 LDCM0361  AC94 HCT 116 C153(0.73); C18(1.19); C19(1.19)  LDD0678  [11]
 LDCM0362  AC95 HCT 116 C153(0.94); C18(1.27); C19(1.27)  LDD0679  [11]
 LDCM0363  AC96 HCT 116 C153(0.94); C18(1.33); C19(1.33)  LDD0680  [11]
 LDCM0364  AC97 HCT 116 C153(0.94); C18(1.59); C19(1.59)  LDD0681  [11]
 LDCM0365  AC98 HCT 116 C153(1.35); C18(1.55); C19(1.55)  LDD0682  [11]
 LDCM0366  AC99 HCT 116 C18(0.87); C19(0.87); C153(1.39)  LDD0683  [11]
 LDCM0248  AKOS034007472 HCT 116 C153(0.75); C18(0.80); C19(0.80)  LDD0565  [11]
 LDCM0356  AKOS034007680 HCT 116 C153(0.88); C18(0.94); C19(0.94)  LDD0673  [11]
 LDCM0275  AKOS034007705 HCT 116 C18(0.85); C19(0.85); C153(1.21)  LDD0592  [11]
 LDCM0156  Aniline NCI-H1299 13.08  LDD0403  [1]
 LDCM0367  CL1 HCT 116 C18(1.17); C19(1.17)  LDD0684  [11]
 LDCM0368  CL10 HCT 116 C18(0.95); C19(0.95)  LDD0685  [11]
 LDCM0369  CL100 HCT 116 C18(0.90); C19(0.90)  LDD0686  [11]
 LDCM0370  CL101 HCT 116 C18(0.93); C19(0.93); C153(1.47)  LDD0687  [11]
 LDCM0371  CL102 HCT 116 C18(0.84); C19(0.84); C153(1.13)  LDD0688  [11]
 LDCM0372  CL103 HCT 116 C18(0.86); C19(0.86); C153(1.59)  LDD0689  [11]
 LDCM0373  CL104 HCT 116 C18(0.89); C19(0.89); C153(1.68)  LDD0690  [11]
 LDCM0374  CL105 HCT 116 C18(0.77); C19(0.77); C153(1.11)  LDD0691  [11]
 LDCM0375  CL106 HCT 116 C18(0.69); C19(0.69); C153(1.33)  LDD0692  [11]
 LDCM0376  CL107 HCT 116 C153(0.76); C18(0.79); C19(0.79)  LDD0693  [11]
 LDCM0377  CL108 HCT 116 C18(0.73); C19(0.73); C153(1.05)  LDD0694  [11]
 LDCM0378  CL109 HCT 116 C18(0.97); C19(0.97); C153(1.43)  LDD0695  [11]
 LDCM0379  CL11 HCT 116 C18(1.06); C19(1.06)  LDD0696  [11]
 LDCM0380  CL110 HCT 116 C18(0.74); C19(0.74); C153(1.92)  LDD0697  [11]
 LDCM0381  CL111 HCT 116 C18(0.70); C19(0.70); C153(1.72)  LDD0698  [11]
 LDCM0382  CL112 HEK-293T C6(0.96)  LDD1586  [12]
 LDCM0383  CL113 HEK-293T C6(1.10)  LDD1587  [12]
 LDCM0384  CL114 HEK-293T C6(1.10); C153(2.62)  LDD1588  [12]
 LDCM0385  CL115 HEK-293T C6(0.96); C153(2.22)  LDD1589  [12]
 LDCM0386  CL116 HEK-293T C6(0.91)  LDD1590  [12]
 LDCM0387  CL117 HCT 116 C153(1.78)  LDD0704  [11]
 LDCM0388  CL118 HCT 116 C153(1.71)  LDD0705  [11]
 LDCM0389  CL119 HCT 116 C153(1.26)  LDD0706  [11]
 LDCM0390  CL12 HCT 116 C18(1.08); C19(1.08)  LDD0707  [11]
 LDCM0391  CL120 HCT 116 C153(0.85)  LDD0708  [11]
 LDCM0392  CL121 HCT 116 C153(1.00)  LDD0709  [11]
 LDCM0393  CL122 HCT 116 C153(1.52)  LDD0710  [11]
 LDCM0394  CL123 HCT 116 C153(1.06)  LDD0711  [11]
 LDCM0395  CL124 HCT 116 C153(1.18)  LDD0712  [11]
 LDCM0396  CL125 HCT 116 C18(0.58); C19(0.58)  LDD0713  [11]
 LDCM0397  CL126 HCT 116 C18(0.60); C19(0.60)  LDD0714  [11]
 LDCM0398  CL127 HCT 116 C18(0.56); C19(0.56)  LDD0715  [11]
 LDCM0399  CL128 HCT 116 C18(0.87); C19(0.87)  LDD0716  [11]
 LDCM0400  CL13 HCT 116 C18(0.81); C19(0.81)  LDD0717  [11]
 LDCM0401  CL14 HCT 116 C18(0.85); C19(0.85)  LDD0718  [11]
 LDCM0402  CL15 HCT 116 C18(0.98); C19(0.98)  LDD0719  [11]
 LDCM0403  CL16 HCT 116 C18(1.12); C19(1.12)  LDD0720  [11]
 LDCM0404  CL17 HCT 116 C18(0.95); C19(0.95)  LDD0721  [11]
 LDCM0405  CL18 HCT 116 C18(1.10); C19(1.10)  LDD0722  [11]
 LDCM0406  CL19 HCT 116 C18(0.89); C19(0.89)  LDD0723  [11]
 LDCM0407  CL2 HCT 116 C18(0.96); C19(0.96)  LDD0724  [11]
 LDCM0408  CL20 HCT 116 C18(0.96); C19(0.96)  LDD0725  [11]
 LDCM0409  CL21 HCT 116 C18(0.90); C19(0.90)  LDD0726  [11]
 LDCM0410  CL22 HCT 116 C18(0.82); C19(0.82)  LDD0727  [11]
 LDCM0411  CL23 HCT 116 C18(1.09); C19(1.09)  LDD0728  [11]
 LDCM0412  CL24 HCT 116 C18(1.07); C19(1.07)  LDD0729  [11]
 LDCM0413  CL25 HCT 116 C18(1.07); C19(1.07)  LDD0730  [11]
 LDCM0414  CL26 HCT 116 C18(1.16); C19(1.16)  LDD0731  [11]
 LDCM0415  CL27 HCT 116 C18(1.01); C19(1.01)  LDD0732  [11]
 LDCM0416  CL28 HCT 116 C18(0.97); C19(0.97)  LDD0733  [11]
 LDCM0417  CL29 HCT 116 C18(1.04); C19(1.04)  LDD0734  [11]
 LDCM0418  CL3 HCT 116 C18(1.14); C19(1.14)  LDD0735  [11]
 LDCM0419  CL30 HCT 116 C18(1.08); C19(1.08)  LDD0736  [11]
 LDCM0420  CL31 HEK-293T C6(1.09); C153(4.18); C294(0.98); C18(0.86)  LDD1624  [12]
 LDCM0421  CL32 HCT 116 C18(0.84); C19(0.84)  LDD0738  [11]
 LDCM0422  CL33 HCT 116 C18(0.98); C19(0.98)  LDD0739  [11]
 LDCM0423  CL34 HCT 116 C18(0.71); C19(0.71)  LDD0740  [11]
 LDCM0424  CL35 HCT 116 C18(1.07); C19(1.07)  LDD0741  [11]
 LDCM0425  CL36 HCT 116 C18(0.74); C19(0.74)  LDD0742  [11]
 LDCM0426  CL37 HCT 116 C18(0.79); C19(0.79)  LDD0743  [11]
 LDCM0428  CL39 HCT 116 C18(1.10); C19(1.10)  LDD0745  [11]
 LDCM0429  CL4 HCT 116 C18(1.05); C19(1.05)  LDD0746  [11]
 LDCM0430  CL40 HCT 116 C18(0.93); C19(0.93)  LDD0747  [11]
 LDCM0431  CL41 HCT 116 C18(0.92); C19(0.92)  LDD0748  [11]
 LDCM0432  CL42 HCT 116 C18(0.74); C19(0.74)  LDD0749  [11]
 LDCM0433  CL43 HCT 116 C18(1.00); C19(1.00)  LDD0750  [11]
 LDCM0434  CL44 HCT 116 C18(0.75); C19(0.75)  LDD0751  [11]
 LDCM0435  CL45 HCT 116 C18(0.87); C19(0.87)  LDD0752  [11]
 LDCM0436  CL46 HCT 116 C153(6.18)  LDD0753  [11]
 LDCM0437  CL47 HCT 116 C153(1.98)  LDD0754  [11]
 LDCM0438  CL48 HCT 116 C153(6.73)  LDD0755  [11]
 LDCM0439  CL49 HCT 116 C153(0.98)  LDD0756  [11]
 LDCM0440  CL5 HCT 116 C18(1.04); C19(1.04)  LDD0757  [11]
 LDCM0441  CL50 HCT 116 C153(1.34)  LDD0758  [11]
 LDCM0442  CL51 HCT 116 C153(1.89)  LDD0759  [11]
 LDCM0443  CL52 HCT 116 C153(9.21)  LDD0760  [11]
 LDCM0444  CL53 HCT 116 C153(1.50)  LDD0761  [11]
 LDCM0445  CL54 HCT 116 C153(4.12)  LDD0762  [11]
 LDCM0446  CL55 HCT 116 C153(3.92)  LDD0763  [11]
 LDCM0447  CL56 HCT 116 C153(1.12)  LDD0764  [11]
 LDCM0448  CL57 HCT 116 C153(4.32)  LDD0765  [11]
 LDCM0449  CL58 HCT 116 C153(9.22)  LDD0766  [11]
 LDCM0450  CL59 HCT 116 C153(1.57)  LDD0767  [11]
 LDCM0451  CL6 HCT 116 C18(1.19); C19(1.19)  LDD0768  [11]
 LDCM0452  CL60 HCT 116 C153(1.26)  LDD0769  [11]
 LDCM0453  CL61 HCT 116 C18(0.92); C19(0.92)  LDD0770  [11]
 LDCM0454  CL62 HCT 116 C18(1.06); C19(1.06)  LDD0771  [11]
 LDCM0455  CL63 HCT 116 C18(0.96); C19(0.96)  LDD0772  [11]
 LDCM0456  CL64 HCT 116 C18(1.00); C19(1.00)  LDD0773  [11]
 LDCM0457  CL65 HCT 116 C18(0.81); C19(0.81)  LDD0774  [11]
 LDCM0458  CL66 HCT 116 C18(1.06); C19(1.06)  LDD0775  [11]
 LDCM0459  CL67 HCT 116 C18(1.03); C19(1.03)  LDD0776  [11]
 LDCM0460  CL68 HCT 116 C18(1.01); C19(1.01)  LDD0777  [11]
 LDCM0461  CL69 HCT 116 C18(1.09); C19(1.09)  LDD0778  [11]
 LDCM0462  CL7 HCT 116 C18(0.81); C19(0.81)  LDD0779  [11]
 LDCM0463  CL70 HCT 116 C18(1.06); C19(1.06)  LDD0780  [11]
 LDCM0464  CL71 HCT 116 C18(1.30); C19(1.30)  LDD0781  [11]
 LDCM0465  CL72 HCT 116 C18(1.12); C19(1.12)  LDD0782  [11]
 LDCM0466  CL73 HCT 116 C18(1.12); C19(1.12)  LDD0783  [11]
 LDCM0467  CL74 HCT 116 C18(1.15); C19(1.15)  LDD0784  [11]
 LDCM0469  CL76 HCT 116 C153(1.63); C18(0.82); C19(0.82)  LDD0786  [11]
 LDCM0470  CL77 HCT 116 C153(1.58); C18(0.66); C19(0.66)  LDD0787  [11]
 LDCM0471  CL78 HCT 116 C153(2.56); C18(0.83); C19(0.83)  LDD0788  [11]
 LDCM0472  CL79 HCT 116 C153(1.01); C18(0.71); C19(0.71)  LDD0789  [11]
 LDCM0473  CL8 HCT 116 C18(1.31); C19(1.31)  LDD0790  [11]
 LDCM0474  CL80 HCT 116 C153(0.91); C18(0.70); C19(0.70)  LDD0791  [11]
 LDCM0475  CL81 HCT 116 C153(0.93); C18(0.70); C19(0.70)  LDD0792  [11]
 LDCM0476  CL82 HCT 116 C153(1.25); C18(0.61); C19(0.61)  LDD0793  [11]
 LDCM0477  CL83 HCT 116 C153(1.15); C18(0.79); C19(0.79)  LDD0794  [11]
 LDCM0478  CL84 HCT 116 C153(2.01); C18(0.92); C19(0.92)  LDD0795  [11]
 LDCM0479  CL85 HCT 116 C153(1.02); C18(0.91); C19(0.91)  LDD0796  [11]
 LDCM0480  CL86 HCT 116 C153(1.32); C18(0.70); C19(0.70)  LDD0797  [11]
 LDCM0481  CL87 HCT 116 C153(1.46); C18(0.72); C19(0.72)  LDD0798  [11]
 LDCM0482  CL88 HCT 116 C153(1.04); C18(0.78); C19(0.78)  LDD0799  [11]
 LDCM0483  CL89 HCT 116 C153(1.20); C18(0.69); C19(0.69)  LDD0800  [11]
 LDCM0484  CL9 HCT 116 C18(0.93); C19(0.93)  LDD0801  [11]
 LDCM0485  CL90 HCT 116 C153(1.99); C18(0.68); C19(0.68)  LDD0802  [11]
 LDCM0486  CL91 HCT 116 C18(0.93); C19(0.93)  LDD0803  [11]
 LDCM0487  CL92 HCT 116 C18(0.93); C19(0.93)  LDD0804  [11]
 LDCM0488  CL93 HCT 116 C18(0.80); C19(0.80)  LDD0805  [11]
 LDCM0489  CL94 HCT 116 C18(0.98); C19(0.98)  LDD0806  [11]
 LDCM0490  CL95 HCT 116 C18(1.09); C19(1.09)  LDD0807  [11]
 LDCM0491  CL96 HCT 116 C18(0.84); C19(0.84)  LDD0808  [11]
 LDCM0492  CL97 HCT 116 C18(0.91); C19(0.91)  LDD0809  [11]
 LDCM0493  CL98 HCT 116 C18(1.05); C19(1.05)  LDD0810  [11]
 LDCM0494  CL99 HCT 116 C18(1.01); C19(1.01)  LDD0811  [11]
 LDCM0495  E2913 HEK-293T C6(1.05); C153(2.46)  LDD1698  [12]
 LDCM0576  Fragment14 Ramos C153(2.14)  LDD2193  [13]
 LDCM0580  Fragment21 Ramos C153(1.35)  LDD2195  [13]
 LDCM0582  Fragment23 Ramos C153(1.01)  LDD2196  [13]
 LDCM0586  Fragment28 Ramos C153(10.11)  LDD2198  [13]
 LDCM0588  Fragment30 Ramos C153(3.34)  LDD2199  [13]
 LDCM0589  Fragment31 Ramos C153(0.88)  LDD2200  [13]
 LDCM0468  Fragment33 HCT 116 C18(1.11); C19(1.11)  LDD0785  [11]
 LDCM0596  Fragment38 Ramos C153(0.73)  LDD2203  [13]
 LDCM0566  Fragment4 Ramos C153(3.16)  LDD2184  [13]
 LDCM0427  Fragment51 HCT 116 C18(0.84); C19(0.84)  LDD0744  [11]
 LDCM0614  Fragment56 Ramos C153(0.63)  LDD2205  [13]
 LDCM0615  Fragment63-R Jurkat _(14.59)  LDD1487  [2]
 LDCM0617  Fragment63-S Jurkat _(20.00)  LDD1490  [2]
 LDCM0569  Fragment7 Jurkat _(20.00)  LDD1485  [2]
 LDCM0022  KB02 HEK-293T C153(0.53); C294(1.00); C6(0.93); C19(0.98)  LDD1492  [12]
 LDCM0023  KB03 Jurkat C153(21.96)  LDD0209  [4]
 LDCM0024  KB05 HMCB C52(1.16)  LDD3312  [14]
 LDCM0002  Ward_cp1 U2OS 2.93  LDD0041  [5]

References

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2 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
5 Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells. ACS Chem Biol. 2016 Dec 16;11(12):3268-3272. doi: 10.1021/acschembio.6b00766. Epub 2016 Oct 31.
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
9 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
10 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
11 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
12 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
13 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
14 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840