General Information of Target

Target ID LDTP15492
Target Name Putative tyrosine carboxypeptidase MATCAP2 (MATCAP2)
Gene Name MATCAP2
Gene ID 23366
Synonyms
KIAA0895; Putative tyrosine carboxypeptidase MATCAP2; EC 3.4.17.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPWKEESEFTKQDKAARVIQQAWKSFLNVAIFQHFKSLIDLRRQGEPRQIVKYINPKEAE
LLDAAAGIHVRFRLGGVKFPPDIYYKIFTHRPIEDLCANSPRNYAKLPAKHTSHNKNDHL
QEEDHSGWYHRIENNGWRPVSDTFWLSTDGMVVEDKKESEFHFSKLKRRQDLEKKRKLRK
IEWMRQMYYSGSLEAKSTHHETLGLIHTATKGLIRAFEDGGIDSVMEWEVDEVLNWTNTL
NFDEYIASWKEIATSNSSANFKGFRFNQAQKNIYNYGGDISKMQMGIPDDTYYENVYQEP
NVTRLTPDSTYGL
Target Bioclass
Enzyme
Function Putative tyrosine carboxypeptidase.
Uniprot ID
Q8NCT3
Ensemble ID
ENST00000297063.10
HGNC ID
HGNC:22206

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY4
 Probe Info 
N.A.  LDD0247  [1]

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.