Details of the Target

General Information of Target

Target ID LDTP18740
Target Name Protein SPMIP7 (SPMIP7)
Gene Name SPMIP7
Synonyms
C7orf72; SPATA48; Protein SPMIP7; Sperm microtubule inner protein 7; Spermatogenesis-associated protein 48
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAVQSKAFCAGGLAPGWKLLVQGHADSGEDRFETNFLLETGDIAFHIKPRFSSATVVGNA
FQYGRWGPEQVSSIFPLAPGEPFEIEVSWDAEHFHVYAPEHKVLQFPCRQRPLGATTRVR
VLSDHCLAQVELAKRGLSWGDRGY
Target Bioclass
Other
Function Essential for normal spermatogenesis.
Uniprot ID
A4D263
Ensemble ID
ENST00000297001.7
HGNC ID
HGNC:22564

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY4
 Probe Info  		N.A.  LDD0247  [2]

References

1 Labeling Preferences of Diazirines with Protein Biomolecules. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20.
Mass spectrometry data entry: PXD025140
2 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.