Details of the Target
General Information of Target
| Target ID | LDTP17204 | |||||
|---|---|---|---|---|---|---|
| Target Name | Sodium/bile acid cotransporter 5 (SLC10A5) | |||||
| Gene Name | SLC10A5 | |||||
| Gene ID | 347051 | |||||
| Synonyms |
Sodium/bile acid cotransporter 5; Na(+)/bile acid cotransporter 5; Solute carrier family 10 member 5 |
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| 3D Structure | ||||||
| Sequence |
MTESQGTVTFKDVAIDFTQEEWKRLDPAQRKLYRNVMLENYNNLITVGYPFTKPDVIFKL
EQEEEPWVMEEEVLRRHWQGEIWGVDEHQKNQDRLLRQVEVKFQKTLTEEKGNECQKKFA NVFPLNSDFFPSRHNLYEYDLFGKCLEHNFDCHNNVKCLMRKEHCEYNEPVKSYGNSSSH FVITPFKCNHCGKGFNQTLDLIRHLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQ SYKCNECGKAFIKMSNLIRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKIHTGEKPYEC NECGKAFSQKQSLIAHQKVHTGEKPYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCG KAFSQFSMLIIHVRIHTGEKPYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFS HKKNFITHQKIHTREKPYECNECGKAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQKSN LIAHEKIHSGEKPYECNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKAFSQIASLTLH LRSHTGEKPYECDKCGKAFSQCSLLNLHMRSHTGEKPYVCNECGKAFSQRTSLIVHMRGH TGEKPYECNKCGKAFSQSSSLTIHIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEK PYHCIECGKAFSQKSHLVRHQRIHTH |
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| Target Bioclass |
Transporter and channel
|
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| Family |
Bile acid:sodium symporter (BASS) (TC 2.A.28) family
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| Subcellular location |
Membrane
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
CY4 Probe Info |
 |
D140(0.00); H138(0.00); Q134(0.00); R141(0.00) | LDD0247 | [1] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0161 | [2] | |
References