Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0175
Competitor Name
Ethacrynic acid
Synonyms
ETHACRYNIC ACID; Etacrynic Acid; 58-54-8; ethacrynate; Edecrin; Etacrinic acid; Hydromedin; Taladren; Crinuryl; Edecril; Edecrina; Endecril; Hidromedin; Otacril; Mingit; Reomax; Uregit; Etakrinic acid; Methylenebutyrylphenoxyacetic acid; MK-595; Ethacrinique (acide); Acido etacrinico; Acide etacrynique; Acidum etacrynicum; Kyselina ethakrynova; Kyselina ethakrynova [Czech]; [2,3-Dichloro-4-(2-methylenebutyryl)phenoxy]acetic acid; Acide etacrynique [INN-French]; Acido etacrinico [INN-Spanish]; Acidum etacrynicum [INN-Latin]; (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid; 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid; Methylenebutyryl phenoxyacetic acid; 2,3-Dichloro-4-(2-methylenebutyl)phenoxyacetic acid; MK 595; NSC 85791; NSC 624008; BRN 1915060; Acetic acid, (2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy)-; Etacrynic acid [INN]; 2,3-Dichloro-4-(2-methylenebutyryl)phenoxy acetic acid; (2,3-Dichloro-4-(2-methylenebutyryl)phenoxy)acetic acid; (4-(2-Methylenebutyryl)-2,3-dichlorophenoxy)acetic acid; 2-(2,3-Dichloro-4-(2-methylenebutanoyl)phenoxy)acetic acid; NSC-85791; CHEMBL456; NSC-624008; Acetic acid, [2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-; Kyselina 4-(2-(1-butenyl)karbonyl)-2,3-dichlorfenoxyoctova [Czech]; M5DP350VZV; 58-54-8 (free acid); MLS000069535; MLS002701928; CHEBI:4876; [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid; Kyselina 4-(2-(1-butenyl)karbonyl)-2,3-dichlorfenoxyoctova; DTXSID3025257; Acetic acid, (2,3-dichloro-4-(2-methylenebutyryl)phenoxy)-; NSC85791; NSC624008; CAS-58-54-8; [4-(2-Methylenebutyryl)-2,3-dichlorophenoxy]acetic acid; NCGC00016260-05; 2-[2,3-dichloro-4-(2-methylenebutanoyl)phenoxy]acetic acid; SMR000058600; [2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic acid; Ethacryinic Acid; DTXCID205257; Ethacrynic acid [USAN:BAN]; [2,3-dichloro-4-(2-methylenebutanoyl)phenoxy]acetic acid; CCRIS 4638; HSDB 2136; Ethacrynic acid (USP); SR-01000003010; EINECS 200-384-1; UNII-M5DP350VZV; etacrynicacid; Etacrynsaure; Crinuril; Acetic acid, [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]-; etacrynic-acid; Ethacrynic acid [USAN:USP]; 1gsf; 2gss; Prestwick_671; Opera_ID_61; Spectrum_000813; Prestwick0_000259; Prestwick1_000259; Prestwick2_000259; Prestwick3_000259; Spectrum2_000097; Spectrum3_000425; Spectrum4_000544; Spectrum5_000680; E0526; bmse000134; SCHEMBL26353; BSPBio_000078; BSPBio_002010; ETACRYNIC ACID [JAN]; ETHACRYNIC ACID [MI]; KBioGR_001207; KBioSS_001293; MLS002548854; DivK1c_000900; Etacrynic acid (JP17/INN); SPECTRUM1500287; SPBio_000054; SPBio_002297; ETHACRYNIC ACID [HSDB]; ETHACRYNIC ACID [USAN]; 2,3-Dichloro-4-(2-methylenebutyryl)phenoxyacetic acid; BPBio1_000086; GTPL7179; ETACRYNIC ACID [MART.]; ETHACRYNIC ACID [VANDF]; ETACRYNIC ACID [WHO-DD]; HMS502M22; KBio1_000900; KBio2_001293; KBio2_003861; KBio2_006429; KBio3_001230; NINDS_000900; HMS1568D20; HMS1920M16; HMS2089N17; HMS2091D17; HMS2095D20; HMS3259G03; HMS3712D20; Pharmakon1600-01500287; HY-B1640; Ethacrynic acid, >=97% (HPLC); Tox21_110335; Tox21_201102; BDBM50186231; CCG-38915; ETACRYNIC ACID [EP IMPURITY]; MFCD00056693; NSC757026; s5561; WLN: QV1OR BG CG DVY2&U1; ETACRYNIC ACID [EP MONOGRAPH]; ETHACRYNIC ACID [ORANGE BOOK]; GST Inhibitor-2 (Ethacrynic acid)); AKOS003404732; Tox21_110335_1; DB00903; ETHACRYNIC ACID [USP MONOGRAPH]; KS-1453; MCULE-6140194266; NC00450; NSC-757026; IDI1_000900; NCGC00016260-01; NCGC00016260-02; NCGC00016260-03; NCGC00016260-04; NCGC00016260-06; NCGC00016260-07; NCGC00016260-08; NCGC00016260-09; NCGC00016260-10; NCGC00016260-11; NCGC00016260-13; NCGC00022601-03; NCGC00022601-04; NCGC00022601-05; NCGC00258654-01; NCI60_041898; SBI-0051374.P003; DB-053221; AB00051988; CS-0013591; NS00009284; A51097; D00313; AB00051988-19; AB00051988_20; A831918; Q418571; SR-01000003010-2; SR-01000003010-3; BRD-K63630713-001-05-0; BRD-K63630713-001-15-9; [2,3-Dichloro-4-(2-ethylacryloyl)phenoxy]acetic acid #; Acetic acid,3-dichloro-4-(2-methylenebutyryl)phenoxy]-; Z1590781983; 2,3-DICHLORO-4-(2-METHYLENEBUTYRYL)PHENOXY)ACETATE; 4-(METHYLENEBUTYRYL)-2,3-DICHLOROPHENOXY)ACETIC ACID; Acetic acid,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-; Ethacrynic acid, European Pharmacopoeia (EP) Reference Standard; Ethacrynic acid, United States Pharmacopeia (USP) Reference Standard; 2-(2,3-DICHLORO-4-(2-METHYLENE-1-OXOBUTYL)PHENOXY)ACETIC ACID; Etacrynic acid for system suitability, European Pharmacopoeia (EP) Reference Standard
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 303.13
Lipid-water partition coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C13H12Cl2O4
IUPAC Name
2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Canonical SMILES
CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl
InChI
InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
InChIKey
AVOLMBLBETYQHX-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
EA-probe
 Probe Info  		40 uM Human endocervical adenocarcinoma cell lysate (HeLa) [1]

Target(s) List of this Competitor

196 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 .  LDD0440 
2',5'-phosphodiesterase 12 (PDE12) LDTP07447 .  LDD0440 
26S proteasome non-ATPase regulatory subunit 14 (PSMD14) LDTP00294 .  LDD0440 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 .  LDD0440 
26S proteasome non-ATPase regulatory subunit 7 (PSMD7) LDTP04441 0.77  LDD2210 
26S proteasome non-ATPase regulatory subunit 9 (PSMD9) LDTP00225 0.83  LDD2210 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.21; 1.37; 1.66  LDD2210 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 .  LDD0440 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.94; 1.04  LDD2210 
6-phosphogluconolactonase (PGLS) LDTP14535 .  LDD0440 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 1.96; 4.00; 1.32 ...  LDD2210 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 .  LDD0440 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.96; 0.87  LDD2210 
Actin, cytoplasmic 1 (ACTB) LDTP04876 0.91; 0.81  LDD2210 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 .  LDD0440 
Adenine phosphoribosyltransferase (APRT) LDTP02220 0.77  LDD2210 
ADP-dependent glucokinase (ADPGK) LDTP11127 0.74  LDD2210 
ADP-ribose glycohydrolase MACROD1 (MACROD1) LDTP11059 0.92  LDD2210 
ADP-ribosylation factor 4 (ARF4) LDTP02942 .  LDD0440 
ADP-ribosylation factor 5 (ARF5) LDTP05193 0.83; 0.74; 0.65  LDD2210 
ADP-ribosylation factor 6 (ARF6) LDTP04986 0.85  LDD2210 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 .  LDD0440 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 .  LDD0440 
Alpha-adducin (ADD1) LDTP03770 0.84  LDD2210 
Amidophosphoribosyltransferase (PPAT) LDTP05480 .  LDD0440 
AMP deaminase 2 (AMPD2) LDTP05289 .  LDD0440 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 .  LDD0440 
ATP-citrate synthase (ACLY) LDTP04561 0.76  LDD2210 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 0.67  LDD2210 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 1.66; 1.39  LDD2210 
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (CLPX) LDTP01382 .  LDD0440 
ATP-dependent RNA helicase DDX19A (DDX19A) LDTP12646 0.75  LDD2210 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 0.83; 0.61  LDD2210 
Atypical kinase COQ8B, mitochondrial (COQ8B) LDTP10201 1.51  LDD2210 
Aurora kinase B (AURKB) LDTP10346 .  LDD0440 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 1.23  LDD2210 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.04; 1.14; 0.80  LDD2210 
Calcium/calmodulin-dependent protein kinase type IV (CAMK4) LDTP06558 .  LDD0440 
Calcyclin-binding protein (CACYBP) LDTP12163 .  LDD0440 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 1.05  LDD2210 
Cancer-related nucleoside-triphosphatase (NTPCR) LDTP11152 .  LDD0440 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 2.54  LDD2210 
Caspase-2 (CASP2) LDTP03985 .  LDD0440 
Catechol O-methyltransferase (COMT) LDTP03145 0.66; 0.69  LDD2210 
Cathepsin B (CTSB) LDTP02223 .  LDD0440 
Cathepsin D (CTSD) LDTP02198 .  LDD0440 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 .  LDD0440 
Corrinoid adenosyltransferase MMAB (MMAB) LDTP10286 0.81  LDD2210 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 1.07  LDD2210 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 0.78  LDD2210 
Cytochrome c oxidase subunit 1 (MT-CO1) LDTP01772 0.96  LDD2210 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 .  LDD0440 
Cytochrome c oxidase subunit NDUFA4 (NDUFA4) LDTP00293 1.06; 1.15  LDD2210 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 1.24; 1.60  LDD2210 
DCN1-like protein 5 (DCUN1D5) LDTP11199 .  LDD0440 
Delta(24)-sterol reductase (DHCR24) LDTP06375 .  LDD0440 
Deoxycytidylate deaminase (DCTD) LDTP03643 .  LDD0440 
Desumoylating isopeptidase 1 (DESI1) LDTP07407 0.82  LDD2210 
Dimethyladenosine transferase 2, mitochondrial (TFB2M) LDTP11960 .  LDD0440 
Diphthine--ammonia ligase (DPH6) LDTP15219 1.21  LDD2210 
DNA-3-methyladenine glycosylase (MPG) LDTP03481 .  LDD0440 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 1.61; 0.78  LDD2210 
Dolichol-phosphate mannosyltransferase subunit 1 (DPM1) LDTP01047 .  LDD0440 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LDTP13087 .  LDD0440 
Dolichyl-phosphate beta-glucosyltransferase (ALG5) LDTP14214 .  LDD0440 
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) LDTP03808 0.88  LDD2210 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 0.97; 0.92  LDD2210 
Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4) LDTP04077 0.90  LDD2210 
Dual specificity protein phosphatase 12 (DUSP12) LDTP13663 1.24  LDD2210 
Dynamin-1-like protein (DNM1L) LDTP00273 .  LDD0440 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 .  LDD0440 
E3 ubiquitin-protein ligase RNF114 (RNF114) LDTP14083 0.90  LDD2210 
E3 ubiquitin-protein ligase RNF220 (RNF220) LDTP07216 .  LDD0440 
Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA) LDTP02694 0.83; 0.68  LDD2210 
Electron transfer flavoprotein subunit beta (ETFB) LDTP03849 1.04; 0.93  LDD2210 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 .  LDD0440 
Elongation factor 2 (EEF2) LDTP02672 0.92; 0.79; 0.84  LDD2210 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.96; 0.92; 0.88  LDD2210 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 0.89  LDD2210 
ERO1-like protein alpha (ERO1A) LDTP10386 .  LDD0440 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.98  LDD2210 
Exosome complex component RRP41 (EXOSC4) LDTP12346 .  LDD0440 
FAST kinase domain-containing protein 4 (TBRG4) LDTP10049 .  LDD0440 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 0.73; 0.72  LDD2210 
Fatty acid synthase (FASN) LDTP04243 1.18  LDD2210 
Fatty acyl-CoA reductase 1 (FAR1) LDTP09628 .  LDD0440 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 2.92; 0.93; 15.00 ...  LDD2210 
Glutaredoxin-related protein 5, mitochondrial (GLRX5) LDTP08181 0.80  LDD2210 
Glutaryl-CoA dehydrogenase, mitochondrial (GCDH) LDTP09939 .  LDD0440 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.81; 0.80  LDD2210 
Glycerol-3-phosphate acyltransferase 3 (GPAT3) LDTP06885 1.87  LDD2210 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 1.22; 0.98; 0.88  LDD2210 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 .  LDD0440 
GTPase Era, mitochondrial (ERAL1) LDTP01275 .  LDD0440 
Guanine nucleotide-binding protein-like 3 (GNL3) LDTP11297 .  LDD0440 
Heme oxygenase 2 (HMOX2) LDTP03540 1.55  LDD2210 
Histone-arginine methyltransferase CARM1 (CARM1) LDTP08352 .  LDD0440 
Histone-lysine N-methyltransferase SETDB1 (SETDB1) LDTP06295 .  LDD0440 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 .  LDD0440 
Inosine triphosphate pyrophosphatase (ITPA) LDTP11432 0.95  LDD2210 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 3.25  LDD2210 
Interferon-stimulated gene 20 kDa protein (ISG20) LDTP10104 .  LDD0440 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 1.18  LDD2210 
Kinesin-like protein KIF14 (KIF14) LDTP06303 .  LDD0440 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 2.70; 1.27  LDD2210 
L-xylulose reductase (DCXR) LDTP08082 .  LDD0440 
Leucine carboxyl methyltransferase 1 (LCMT1) LDTP13337 .  LDD0440 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.80  LDD2210 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 0.97  LDD2210 
Lysophosphatidylcholine acyltransferase 2 (LPCAT2) LDTP07967 .  LDD0440 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 0.44  LDD2210 
Methylated-DNA--protein-cysteine methyltransferase (MGMT) LDTP02852 0.64  LDD2210 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 .  LDD0440 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 1.29  LDD2210 
Minor histocompatibility antigen H13 (HM13) LDTP09396 .  LDD0440 
Mitochondrial genome maintenance exonuclease 1 (MGME1) LDTP11090 0.77  LDD2210 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 .  LDD0440 
Multifunctional protein CAD (CAD) LDTP03401 0.99  LDD2210 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 0.76  LDD2210 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 0.89  LDD2210 
NAD-dependent malic enzyme, mitochondrial (ME2) LDTP03220 0.93  LDD2210 
NADH-ubiquinone oxidoreductase chain 3 (MT-ND3) LDTP01984 1.03  LDD2210 
Nucleoside diphosphate kinase 3 (NME3) LDTP05795 .  LDD0440 
Omega-amidase NIT2 (NIT2) LDTP12428 0.84  LDD2210 
Pachytene checkpoint protein 2 homolog (TRIP13) LDTP06432 .  LDD0440 
Peptidyl-prolyl cis-trans isomerase D (PPID) LDTP05573 .  LDD0440 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 .  LDD0440 
Peroxiredoxin-1 (PRDX1) LDTP05503 .  LDD0440 
Peroxiredoxin-2 (PRDX2) LDTP03626 .  LDD0440 
Peroxiredoxin-4 (PRDX4) LDTP05773 .  LDD0440 
Peroxiredoxin-5, mitochondrial (PRDX5) LDTP03512 1.46  LDD2210 
Peroxiredoxin-6 (PRDX6) LDTP03510 0.96  LDD2210 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 .  LDD0440 
Phospholipase A-2-activating protein (PLAA) LDTP13814 .  LDD0440 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 0.71  LDD2210 
Probable ATP-dependent RNA helicase DDX20 (DDX20) LDTP13285 1.15  LDD2210 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 0.98; 0.91  LDD2210 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 .  LDD0440 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 .  LDD0440 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 0.96  LDD2210 
Proteasome subunit beta type-8 (PSMB8) LDTP03411 0.91; 0.80  LDD2210 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 0.81  LDD2210 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 .  LDD0440 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.72  LDD2210 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 .  LDD0440 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.88  LDD2210 
RAC-alpha serine/threonine-protein kinase (AKT1) LDTP03607 .  LDD0440 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 .  LDD0440 
RAF proto-oncogene serine/threonine-protein kinase (RAF1) LDTP02002 .  LDD0440 
Ras-related GTP-binding protein C (RRAGC) LDTP12166 .  LDD0440 
Ras-related protein Rab-13 (RAB13) LDTP04401 .  LDD0440 
Ras-related protein Rab-14 (RAB14) LDTP04901 .  LDD0440 
Ras-related protein Rab-7L1 (RAB29) LDTP00492 1.12; 1.55  LDD2210 
Replication factor C subunit 2 (RFC2) LDTP03726 1.33  LDD2210 
Retinaldehyde dehydrogenase 3 (ALDH1A3) LDTP04134 1.76; 1.26; 1.08 ...  LDD2210 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 .  LDD0440 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 .  LDD0440 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 .  LDD0440 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 0.60  LDD2210 
S-formylglutathione hydrolase (ESD) LDTP02521 0.74  LDD2210 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 0.60  LDD2210 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 .  LDD0440 
Serine/threonine-protein kinase A-Raf (ARAF) LDTP02493 .  LDD0440 
Serine/threonine-protein kinase OSR1 (OXSR1) LDTP01664 0.88  LDD2210 
Serine/threonine-protein kinase PAK 4 (PAK4) LDTP01751 .  LDD0440 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C) LDTP05841 .  LDD0440 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.96; 0.94; 0.90 ...  LDD2210 
Sialic acid synthase (NANS) LDTP12473 .  LDD0440 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 1.04  LDD2210 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 0.89; 0.92  LDD2210 
Spermidine synthase (SRM) LDTP03008 0.81  LDD2210 
Sterol carrier protein 2 (SCP2) LDTP03163 0.97  LDD2210 
TATA-binding protein-associated factor 172 (BTAF1) LDTP00502 .  LDD0440 
Thioredoxin (TXN) LDTP02502 0.76  LDD2210 
Threonylcarbamoyl-AMP synthase (YRDC) LDTP08217 1.55  LDD2210 
Thymidine kinase, cytosolic (TK1) LDTP02022 0.78  LDD2210 
Thymidylate kinase (DTYMK) LDTP03258 .  LDD0440 
Transcription initiation factor IIB (GTF2B) LDTP05240 .  LDD0440 
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (FTSJ1) LDTP13200 .  LDD0440 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.11; 1.04; 0.98 ...  LDD2210 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 1.23; 1.04; 1.03 ...  LDD2210 
Ubiquitin carboxyl-terminal hydrolase 10 (USP10) LDTP06190 .  LDD0440 
Ubiquitin-associated domain-containing protein 2 (UBAC2) LDTP09060 .  LDD0440 
Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) LDTP04874 1.04  LDD2210 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 .  LDD0440 
Ubiquitin-conjugating enzyme E2 S (UBE2S) LDTP06621 .  LDD0440 
Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) LDTP00481 0.91  LDD2210 
UDP-glucose 4-epimerase (GALE) LDTP06111 .  LDD0440 
Uridine-cytidine kinase 1 (UCK1) LDTP12116 .  LDD0440 
Uridine-cytidine kinase 2 (UCK2) LDTP11571 .  LDD0440 
Uridine-cytidine kinase-like 1 (UCKL1) LDTP12745 .  LDD0440 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 .  LDD0440 
Very long chain fatty acid elongase 1 (ELOVL1) LDTP11311 1.09  LDD2210 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 .  LDD0440 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 1.35; 1.76; 1.03  LDD2210 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 1.06; 1.10  LDD2210 
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⏷ Show the Full List of 196 Enzyme
78 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 .  LDD0440 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 0.84  LDD2210 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 .  LDD0440 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 .  LDD0440 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 .  LDD0440 
Annexin A1 (ANXA1) LDTP02010 0.77; 0.84  LDD2210 
Annexin A2 (ANXA2) LDTP02199 .  LDD0440 
ATP synthase protein 8 (MT-ATP8) LDTP01988 0.96  LDD2210 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.26  LDD2210 
BOS complex subunit NCLN (NCLN) LDTP10036 .  LDD0440 
BOS complex subunit TMEM147 (TMEM147) LDTP11292 1.08; 1.46  LDD2210 
Calnexin (CANX) LDTP03405 .  LDD0440 
Catenin delta-1 (CTNND1) LDTP01037 0.93  LDD2210 
CD44 antigen (CD44) LDTP02823 .  LDD0440 
Copine-3 (CPNE3) LDTP01133 0.65  LDD2210 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 0.85  LDD2210 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 .  LDD0440 
EH domain-containing protein 1 (EHD1) LDTP11934 0.93  LDD2210 
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) LDTP01301 .  LDD0440 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 .  LDD0440 
Exportin-1 (XPO1) LDTP00501 .  LDD0440 
Exportin-2 (CSE1L) LDTP04662 .  LDD0440 
Exportin-5 (XPO5) LDTP12142 .  LDD0440 
Exportin-7 (XPO7) LDTP13335 .  LDD0440 
Exportin-T (XPOT) LDTP00810 .  LDD0440 
Gasdermin-D (GSDMD) LDTP04801 1.21  LDD2210 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.91; 0.82  LDD2210 
HIG1 domain family member 2A, mitochondrial (HIGD2A) LDTP15898 1.99  LDD2210 
HLA class II histocompatibility antigen gamma chain (CD74) LDTP02028 .  LDD0440 
Importin subunit alpha-1 (KPNA2) LDTP04501 0.97; 1.12  LDD2210 
Importin subunit beta-1 (KPNB1) LDTP06242 1.26; 1.46; 0.84  LDD2210 
Importin-4 (IPO4) LDTP09515 2.23; 1.10  LDD2210 
Importin-5 (IPO5) LDTP00266 0.75  LDD2210 
Importin-7 (IPO7) LDTP01574 0.76; 1.33  LDD2210 
Large neutral amino acids transporter small subunit 1 (SLC7A5) LDTP05305 .  LDD0440 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 1.03; 1.08  LDD2210 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 1.21  LDD2210 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 0.82  LDD2210 
Mitochondrial glutamate carrier 1 (SLC25A22) LDTP12078 2.11  LDD2210 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 .  LDD0440 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 1.09; 1.00  LDD2210 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 0.88  LDD2210 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 .  LDD0440 
Mpv17-like protein 2 (MPV17L2) LDTP14952 0.89  LDD2210 
Neutral amino acid transporter B(0) (SLC1A5) LDTP06462 1.34; 1.02; 1.23  LDD2210 
Nuclear pore complex protein Nup155 (NUP155) LDTP01295 0.85  LDD2210 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 1.16  LDD2210 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 1.24  LDD2210 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 .  LDD0440 
Nucleoporin NDC1 (NDC1) LDTP11213 1.31  LDD2210 
Nucleoporin NUP35 (NUP35) LDTP09204 0.75  LDD2210 
Oligosaccharyltransferase complex subunit OSTC (OSTC) LDTP12526 1.05; 1.13  LDD2210 
Peroxisomal biogenesis factor 3 (PEX3) LDTP04749 1.81  LDD2210 
PRA1 family protein 2 (PRAF2) LDTP01060 1.06  LDD2210 
Protein Mpv17 (MPV17) LDTP03869 1.18; 2.29  LDD2210 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 .  LDD0440 
Protein transport protein Sec61 subunit beta (SEC61B) LDTP04866 .  LDD0440 
Protein YIPF3 (YIPF3) LDTP11626 .  LDD0440 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 1.21  LDD2210 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.91  LDD2210 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 .  LDD0440 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 .  LDD0440 
Sorting nexin-27 (SNX27) LDTP10533 .  LDD0440 
Sorting nexin-8 (SNX8) LDTP14173 .  LDD0440 
Stomatin (STOM) LDTP03380 .  LDD0440 
Surfeit locus protein 4 (SURF4) LDTP00592 1.20; 1.26  LDD2210 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 .  LDD0440 
Transmembrane protein 126A (TMEM126A) LDTP15948 .  LDD0440 
Transmembrane protein 214 (TMEM214) LDTP07477 .  LDD0440 
Transmembrane protein 33 (TMEM33) LDTP04787 .  LDD0440 
Transmembrane protein 70, mitochondrial (TMEM70) LDTP11229 .  LDD0440 
Transportin-1 (TNPO1) LDTP09949 .  LDD0440 
Transportin-2 (TNPO2) LDTP00434 1.11; 2.81; 1.24 ...  LDD2210 
Transportin-3 (TNPO3) LDTP14133 .  LDD0440 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 .  LDD0440 
V-type proton ATPase subunit H (ATP6V1H) LDTP13319 .  LDD0440 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 .  LDD0440 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 .  LDD0440 
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⏷ Show the Full List of 78 Transporter and channel
14 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Aryl hydrocarbon receptor (AHR) LDTP03790 .  LDD0440 
eIF5-mimic protein 1 (BZW2) LDTP14241 .  LDD0440 
eIF5-mimic protein 2 (BZW1) LDTP07940 1.08; 1.62; 1.38  LDD2210 
Forkhead box protein K1 (FOXK1) LDTP05201 .  LDD0440 
Myocyte-specific enhancer factor 2D (MEF2D) LDTP06215 .  LDD0440 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 .  LDD0440 
Nuclear factor of activated T-cells, cytoplasmic 2 (NFATC2) LDTP05883 .  LDD0440 
Nuclear receptor corepressor 2 (NCOR2) LDTP14199 .  LDD0440 
Nuclear receptor subfamily 2 group F member 6 (NR2F6) LDTP02500 1.06  LDD2210 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 0.72  LDD2210 
Transcription factor JunB (JUNB) LDTP02892 .  LDD0440 
Transcription factor SOX-10 (SOX10) LDTP04752 2.07; 0.91  LDD2210 
Transcription factor SOX-5 (SOX5) LDTP03781 .  LDD0440 
Transcriptional repressor p66-beta (GATAD2B) LDTP09710 .  LDD0440 
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⏷ Show the Full List of 14 Transcription factor
1 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Tapasin (TAPBP) LDTP00671 1.04  LDD2210 
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2 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7) LDTP10323 0.91; 0.83  LDD2210 
Interleukin-13 receptor subunit alpha-2 (IL13RA2) LDTP06163 .  LDD0440 
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197 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
182 kDa tankyrase-1-binding protein (TNKS1BP1) LDTP11597 .  LDD0440 
A-kinase anchor protein 8 (AKAP8) LDTP00880 .  LDD0440 
A-kinase anchor protein 8-like (AKAP8L) LDTP13591 .  LDD0440 
Actin-related protein 2 (ACTR2) LDTP04903 .  LDD0440 
ADP-ribosylation factor-binding protein GGA2 (GGA2) LDTP13414 .  LDD0440 
AH receptor-interacting protein (AIP) LDTP00202 .  LDD0440 
Alpha-2-macroglobulin (A2M) LDTP01814 .  LDD0440 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 .  LDD0440 
Anamorsin (CIAPIN1) LDTP07385 .  LDD0440 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 .  LDD0440 
Armadillo repeat-containing protein 6 (ARMC6) LDTP15101 .  LDD0440 
Ataxin-10 (ATXN10) LDTP13091 .  LDD0440 
Ataxin-7-like protein 3B (ATXN7L3B) LDTP15730 0.99; 0.85  LDD2210 
Beta-2-syntrophin (SNTB2) LDTP05864 .  LDD0440 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 1.48  LDD2210 
Breast cancer anti-estrogen resistance protein 3 (BCAR3) LDTP01316 .  LDD0440 
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (ARFGEF1) LDTP14238 .  LDD0440 
Calponin-2 (CNN2) LDTP10864 .  LDD0440 
Calponin-3 (CNN3) LDTP06383 .  LDD0440 
Cancer/testis antigen 1 (CTAG1A; CTAG1B) LDTP05106 .  LDD0440 
CDGSH iron-sulfur domain-containing protein 2 (CISD2) LDTP08902 0.91  LDD2210 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 .  LDD0440 
Chromobox protein homolog 3 (CBX3) LDTP05778 1.01  LDD2210 
Cip1-interacting zinc finger protein (CIZ1) LDTP13579 .  LDD0440 
CLIP-associating protein 1 (CLASP1) LDTP08062 .  LDD0440 
CLIP-associating protein 2 (CLASP2) LDTP01129 .  LDD0440 
Cofilin-1 (CFL1) LDTP03244 0.94; 0.88  LDD2210 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 .  LDD0440 
Condensin-2 complex subunit G2 (NCAPG2) LDTP08359 .  LDD0440 
Conserved oligomeric Golgi complex subunit 7 (COG7) LDTP05185 .  LDD0440 
COP9 signalosome complex subunit 7a (COPS7A) LDTP13170 0.98  LDD2210 
Coronin-1C (CORO1C) LDTP13580 .  LDD0440 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 1.05  LDD2210 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 .  LDD0440 
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) LDTP14179 1.18; 1.28; 0.78 ...  LDD2210 
Cytosolic iron-sulfur assembly component 2B (CIAO2B) LDTP13979 1.15  LDD2210 
Destrin (DSTN) LDTP04887 0.78  LDD2210 
DNA mismatch repair protein Msh2 (MSH2) LDTP04028 .  LDD0440 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 0.92  LDD2210 
DNA replication complex GINS protein PSF3 (GINS3) LDTP11139 .  LDD0440 
Dynactin subunit 4 (DCTN4) LDTP13402 1.06; 0.98  LDD2210 
Dynein axonemal assembly factor 5 (DNAAF5) LDTP08387 1.08  LDD2210 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 1.06; 0.96  LDD2210 
Echinoderm microtubule-associated protein-like 4 (EML4) LDTP12214 .  LDD0440 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 .  LDD0440 
ELAV-like protein 1 (ELAVL1) LDTP06450 .  LDD0440 
Elongation factor 1-gamma (EEF1G) LDTP03367 2.54; 0.90  LDD2210 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 .  LDD0440 
Enhancer of mRNA-decapping protein 4 (EDC4) LDTP07521 .  LDD0440 
Eukaryotic translation initiation factor 3 subunit D (EIF3D) LDTP00619 0.87  LDD2210 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 0.94; 0.86; 0.79  LDD2210 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 .  LDD0440 
Galectin-3-binding protein (LGALS3BP) LDTP05558 .  LDD0440 
Gamma-tubulin complex component 2 (TUBGCP2) LDTP11159 .  LDD0440 
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (GBF1) LDTP09783 .  LDD0440 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 0.99  LDD2210 
HAUS augmin-like complex subunit 6 (HAUS6) LDTP08069 .  LDD0440 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.72  LDD2210 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.86  LDD2210 
Heat shock protein beta-1 (HSPB1) LDTP02053 .  LDD0440 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 .  LDD0440 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.08; 0.97  LDD2210 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 .  LDD0440 
Hippocalcin-like protein 1 (HPCAL1) LDTP03841 0.77  LDD2210 
Histone H3.3 (H3-3A; H3-3B) LDTP05198 1.08; 1.10  LDD2210 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 .  LDD0440 
Insulin receptor substrate 2 (IRS2) LDTP14059 .  LDD0440 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 .  LDD0440 
Kinesin light chain 4 (KLC4) LDTP12591 .  LDD0440 
Kinetochore-associated protein NSL1 homolog (NSL1) LDTP10433 .  LDD0440 
La-related protein 1 (LARP1) LDTP07605 .  LDD0440 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 .  LDD0440 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 .  LDD0440 
Laminin subunit gamma-1 (LAMC1) LDTP02535 .  LDD0440 
LanC-like protein 2 (LANCL2) LDTP12571 0.80; 0.81  LDD2210 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 0.93  LDD2210 
Large ribosomal subunit protein eL19 (RPL19) LDTP05196 .  LDD0440 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 .  LDD0440 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 .  LDD0440 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 0.58  LDD2210 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 1.07  LDD2210 
Large ribosomal subunit protein P1 (RPLP1) LDTP02107 0.72  LDD2210 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 0.99; 0.83  LDD2210 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 1.02  LDD2210 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 .  LDD0440 
Large ribosomal subunit protein uL14m (MRPL14) LDTP15108 .  LDD0440 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 0.97; 0.99  LDD2210 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 1.07  LDD2210 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 .  LDD0440 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.86  LDD2210 
Latent-transforming growth factor beta-binding protein 3 (LTBP3) LDTP12554 .  LDD0440 
Leucine zipper protein 1 (LUZP1) LDTP08273 .  LDD0440 
Leucine-rich repeat-containing protein 41 (LRRC41) LDTP06362 .  LDD0440 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 .  LDD0440 
Mediator of RNA polymerase II transcription subunit 17 (MED17) LDTP12669 0.89  LDD2210 
Melanoma-associated antigen 10 (MAGEA10) LDTP14683 .  LDD0440 
Melanoma-associated antigen 4 (MAGEA4) LDTP04041 .  LDD0440 
Melanoma-associated antigen D2 (MAGED2) LDTP13657 .  LDD0440 
Metalloproteinase inhibitor 3 (TIMP3) LDTP03773 .  LDD0440 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 1.03; 1.09  LDD2210 
MICOS complex subunit MIC27 (APOOL) LDTP07718 1.22  LDD2210 
Microtubule-associated protein 4 (MAP4) LDTP03404 .  LDD0440 
Mitochondrial fission regulator 1-like (MTFR1L) LDTP15947 1.08  LDD2210 
Mitochondrial import inner membrane translocase subunit Tim21 (TIMM21) LDTP11304 .  LDD0440 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 .  LDD0440 
Multifunctional methyltransferase subunit TRM112-like protein (TRMT112) LDTP13323 1.01; 1.02  LDD2210 
Myb-binding protein 1A (MYBBP1A) LDTP11079 .  LDD0440 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 .  LDD0440 
NF-kappa-B essential modulator (IKBKG) LDTP14268 .  LDD0440 
NGFI-A-binding protein 2 (NAB2) LDTP06456 .  LDD0440 
NHP2-like protein 1 (SNU13) LDTP04708 0.70  LDD2210 
Nuclear migration protein nudC (NUDC) LDTP13817 0.85  LDD2210 
Nucleolar complex protein 2 homolog (NOC2L) LDTP14011 .  LDD0440 
Nucleolar protein 56 (NOP56) LDTP00313 2.16; 1.94; 1.69 ...  LDD2210 
Nucleolar protein 58 (NOP58) LDTP13925 2.34  LDD2210 
Nucleophosmin (NPM1) LDTP02164 .  LDD0440 
Origin recognition complex subunit 6 (ORC6) LDTP14139 .  LDD0440 
Oxysterol-binding protein-related protein 3 (OSBPL3) LDTP11930 .  LDD0440 
Peflin (PEF1) LDTP13167 .  LDD0440 
Perilipin-2 (PLIN2) LDTP10889 .  LDD0440 
Pleckstrin homology-like domain family B member 2 (PHLDB2) LDTP08172 .  LDD0440 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 .  LDD0440 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 .  LDD0440 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 .  LDD0440 
Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 .  LDD0440 
Prefoldin subunit 2 (PFDN2) LDTP13309 .  LDD0440 
Prefoldin subunit 3 (VBP1) LDTP04935 .  LDD0440 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.92  LDD2210 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 .  LDD0440 
Proteasome inhibitor PI31 subunit (PSMF1) LDTP09779 .  LDD0440 
Protein HGH1 homolog (HGH1) LDTP18309 .  LDD0440 
Protein ITPRID2 (ITPRID2) LDTP03426 .  LDD0440 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 0.81  LDD2210 
Protein misato homolog 1 (MSTO1) LDTP11239 0.95  LDD2210 
Protein odr-4 homolog (ODR4) LDTP17214 .  LDD0440 
Protein sprouty homolog 2 (SPRY2) LDTP00812 .  LDD0440 
Protein transport protein Sec16A (SEC16A) LDTP00512 .  LDD0440 
Protein unc-45 homolog A (UNC45A) LDTP11890 .  LDD0440 
Pumilio homolog 1 (PUM1) LDTP06174 .  LDD0440 
Ran-binding protein 9 (RANBP9) LDTP10802 .  LDD0440 
Rap guanine nucleotide exchange factor 6 (RAPGEF6) LDTP09509 .  LDD0440 
Rap1 GTPase-GDP dissociation stimulator 1 (RAP1GDS1) LDTP04504 0.64; 0.92  LDD2210 
Ras GTPase-activating-like protein IQGAP3 (IQGAP3) LDTP08288 .  LDD0440 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 .  LDD0440 
Regulation of nuclear pre-mRNA domain-containing protein 2 (RPRD2) LDTP07213 .  LDD0440 
Ribosomal protein eS27-like (RPS27L) LDTP07909 .  LDD0440 
RRP12-like protein (RRP12) LDTP14980 1.05  LDD2210 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 0.80  LDD2210 
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2) LDTP12800 1.03  LDD2210 
SHC-transforming protein 1 (SHC1) LDTP03479 .  LDD0440 
Sideroflexin-3 (SFXN3) LDTP11331 .  LDD0440 
Signal recognition particle receptor subunit alpha (SRPRA) LDTP02263 .  LDD0440 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 .  LDD0440 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 .  LDD0440 
Sister chromatid cohesion protein PDS5 homolog B (PDS5B) LDTP12605 .  LDD0440 
Small ribosomal subunit protein bS21m (MRPS21) LDTP14791 .  LDD0440 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 0.77  LDD2210 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 1.08  LDD2210 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 .  LDD0440 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.99  LDD2210 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 .  LDD0440 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.15  LDD2210 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.94; 0.85; 0.78  LDD2210 
Smoothelin (SMTN) LDTP04590 .  LDD0440 
Spartin (SPART) LDTP08735 .  LDD0440 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 .  LDD0440 
Src substrate cortactin (CTTN) LDTP06094 .  LDD0440 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 .  LDD0440 
Symplekin (SYMPK) LDTP09878 .  LDD0440 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 1.22  LDD2210 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.81  LDD2210 
T-complex protein 1 subunit eta (CCT7) LDTP10990 5.04; 1.10; 15.00 ...  LDD2210 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.92  LDD2210 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.77  LDD2210 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.96  LDD2210 
TBC1 domain family member 13 (TBC1D13) LDTP16107 0.79  LDD2210 
Telomere length regulation protein TEL2 homolog (TELO2) LDTP14072 .  LDD0440 
Testis-expressed protein 264 (TEX264) LDTP14259 .  LDD0440 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 .  LDD0440 
TIP41-like protein (TIPRL) LDTP01285 1.07  LDD2210 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 .  LDD0440 
Trafficking protein particle complex subunit 1 (TRAPPC1) LDTP14153 1.45  LDD2210 
Trafficking protein particle complex subunit 4 (TRAPPC4) LDTP13837 1.03  LDD2210 
Transcription initiation factor TFIID subunit 6 (TAF6) LDTP04321 .  LDD0440 
Transforming acidic coiled-coil-containing protein 1 (TACC1) LDTP01210 .  LDD0440 
Translation initiation factor eIF2 assembly protein (CDC123) LDTP16826 .  LDD0440 
Treacle protein (TCOF1) LDTP05867 1.34; 2.88  LDD2210 
Tubulin beta chain (TUBB) LDTP02205 .  LDD0440 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 .  LDD0440 
UPF0598 protein C8orf82 (C8orf82) LDTP19499 1.01  LDD2210 
UPF0696 protein C11orf68 (C11orf68) LDTP11866 .  LDD0440 
Vacuolar protein sorting-associated protein 28 homolog (VPS28) LDTP13424 0.97  LDD2210 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 .  LDD0440 
WD repeat domain phosphoinositide-interacting protein 2 (WIPI2) LDTP14069 1.25  LDD2210 
WD repeat-containing protein 26 (WDR26) LDTP12023 .  LDD0440 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 .  LDD0440 
Zinc finger protein ubi-d4 (DPF2) LDTP09872 .  LDD0440 
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⏷ Show the Full List of 197 Other

Full Information of The Labelling Profiles of This Competitor

EA-probe
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 40 uM
Quantitative Method Isotope tag
Experimemt Name RD-ABPP
Competitor Name Ethacrynic acid
Competitor Concentration 200 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)
Interaction Atlas ID  LDD0440  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 40 uM
Quantitative Method Isotope tag
Competitor Name Ethacrynic acid
Competitor Concentration 10 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)
Interaction Atlas ID  LDD2210  Download The Altas
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 40 uM
Quantitative Method Isotope tag
Competitor Name Ethacrynic acid
Competitor Concentration 20 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)
Interaction Atlas ID  LDD2211  Download The Altas
  
Experiment 4 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 40 uM
Quantitative Method Isotope tag
Competitor Name Ethacrynic acid
Competitor Concentration 40 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)
Interaction Atlas ID  LDD2212  Download The Altas

References

1 Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol Pharm. 2018 Jun 4;15(6):2413-2422. doi: 10.1021/acs.molpharmaceut.8b00250. Epub 2018 May 15.