Details of the Target

General Information of Target

Target ID LDTP10323
Target Name CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7)
Gene Name CMTM7
Gene ID 112616
Synonyms
CKLFSF7; CKLF-like MARVEL transmembrane domain-containing protein 7; Chemokine-like factor superfamily member 7
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MCGRTSCHLPRDVLTRACAYQDRRGQQRLPEWRDPDKYCPSYNKSPQSNSPVLLSRLHFE
KDADSSERIIAPMRWGLVPSWFKESDPSKLQFNTTNCRSDTVMEKRSFKVPLGKGRRCVV
LADGFYEWQRCQGTNQRQPYFIYFPQIKTEKSGSIGAADSPENWEKVWDNWRLLTMAGIF
DCWEPPEGGDVLYSYTIITVDSCKGLSDIHHRMPAILDGEEAVSKWLDFGEVSTQEALKL
IHPTENITFHAVSSVVNNSRNNTPECLAPVDLVVKKELRASGSSQRMLQWLATKSPKKED
SKTPQKEESDVPQWSSQFLQKSPLPTKRGTAGLLEQWLKREKEEEPVAKRPYSQ
Target Bioclass
Cytokine and receptor
Family
Chemokine-like factor family
Subcellular location
Membrane
Uniprot ID
Q96FZ5
Ensemble ID
ENST00000334983.10
HGNC ID
HGNC:19178

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C12(2.25)  LDD0304  [1]
JZ128-DTB
 Probe Info  		N.A.  LDD0462  [2]
AHL-Pu-1
 Probe Info  		C12(4.15)  LDD0169  [3]
EA-probe
 Probe Info  		C12(0.91); C12(0.83)  LDD2210  [4]
DBIA
 Probe Info  		C12(1.19)  LDD0602  [5]
NAIA_4
 Probe Info  		N.A.  LDD2226  [6]
IPM
 Probe Info  		N.A.  LDD2156  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C12(4.15)  LDD0169  [3]
 LDCM0214  AC1 PaTu 8988t C12(1.12)  LDD1093  [5]
 LDCM0215  AC10 HEK-293T C166(0.97); C12(1.04)  LDD1508  [8]
 LDCM0226  AC11 HEK-293T C166(1.03); C12(0.89)  LDD1509  [8]
 LDCM0237  AC12 HEK-293T C166(1.01); C12(1.02)  LDD1510  [8]
 LDCM0259  AC14 HEK-293T C12(1.05)  LDD1512  [8]
 LDCM0270  AC15 HEK-293T C12(1.02)  LDD1513  [8]
 LDCM0276  AC17 HEK-293T C166(0.84); C12(0.98)  LDD1515  [8]
 LDCM0277  AC18 HEK-293T C166(0.82); C12(0.94)  LDD1516  [8]
 LDCM0278  AC19 HEK-293T C166(0.98); C12(1.05)  LDD1517  [8]
 LDCM0279  AC2 PaTu 8988t C12(1.21)  LDD1158  [5]
 LDCM0280  AC20 HEK-293T C166(0.90); C12(0.92)  LDD1519  [8]
 LDCM0281  AC21 HEK-293T C12(1.03)  LDD1520  [8]
 LDCM0282  AC22 HEK-293T C12(0.94)  LDD1521  [8]
 LDCM0283  AC23 HEK-293T C12(1.05)  LDD1522  [8]
 LDCM0284  AC24 HEK-293T C166(0.96); C12(0.92)  LDD1523  [8]
 LDCM0285  AC25 HCT 116 C12(1.19)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C12(1.14)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C12(1.15)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C12(1.04)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C12(1.08)  LDD0606  [5]
 LDCM0290  AC3 PaTu 8988t C12(1.33)  LDD1169  [5]
 LDCM0291  AC30 HCT 116 C12(1.25)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C12(1.16)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C12(1.41)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C12(1.22)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C12(1.24)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C12(0.91)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C12(1.07)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C12(1.43)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C12(0.95)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C12(1.51)  LDD0617  [5]
 LDCM0301  AC4 PaTu 8988t C12(1.06)  LDD1180  [5]
 LDCM0302  AC40 HCT 116 C12(1.32)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C12(1.19)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C12(1.50)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C12(1.13)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C12(1.36)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C12(1.36)  LDD0624  [5]
 LDCM0308  AC46 PaTu 8988t C12(1.12)  LDD1187  [5]
 LDCM0309  AC47 PaTu 8988t C12(1.73)  LDD1188  [5]
 LDCM0310  AC48 PaTu 8988t C12(1.63)  LDD1189  [5]
 LDCM0311  AC49 PaTu 8988t C12(1.05)  LDD1190  [5]
 LDCM0312  AC5 PaTu 8988t C12(1.02)  LDD1191  [5]
 LDCM0313  AC50 PaTu 8988t C12(1.18)  LDD1192  [5]
 LDCM0314  AC51 PaTu 8988t C12(1.12)  LDD1193  [5]
 LDCM0315  AC52 PaTu 8988t C12(1.56)  LDD1194  [5]
 LDCM0316  AC53 PaTu 8988t C12(2.13)  LDD1195  [5]
 LDCM0317  AC54 PaTu 8988t C12(1.40)  LDD1196  [5]
 LDCM0318  AC55 PaTu 8988t C12(1.99)  LDD1197  [5]
 LDCM0319  AC56 PaTu 8988t C12(1.96)  LDD1198  [5]
 LDCM0320  AC57 HCT 116 C12(1.18)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C12(1.07)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C12(1.35)  LDD0639  [5]
 LDCM0323  AC6 HEK-293T C12(0.89)  LDD1562  [8]
 LDCM0324  AC60 HCT 116 C12(1.71)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C12(0.98)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C12(1.49)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C12(1.30)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C12(1.65)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C12(1.96)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C12(1.99)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C12(1.94)  LDD0648  [5]
 LDCM0334  AC7 HEK-293T C12(0.86)  LDD1568  [8]
 LDCM0345  AC8 HEK-293T C166(1.01); C12(1.00)  LDD1569  [8]
 LDCM0248  AKOS034007472 HEK-293T C12(0.98)  LDD1511  [8]
 LDCM0356  AKOS034007680 HEK-293T C166(0.90); C12(0.98)  LDD1570  [8]
 LDCM0275  AKOS034007705 HEK-293T C166(1.04); C12(1.02)  LDD1514  [8]
 LDCM0367  CL1 PaTu 8988t C12(0.99)  LDD1246  [5]
 LDCM0368  CL10 PaTu 8988t C12(1.57)  LDD1247  [5]
 LDCM0369  CL100 PaTu 8988t C12(0.98)  LDD1248  [5]
 LDCM0370  CL101 HEK-293T C12(0.90)  LDD1574  [8]
 LDCM0371  CL102 HEK-293T C166(0.90); C12(0.82)  LDD1575  [8]
 LDCM0372  CL103 HEK-293T C166(0.91); C12(0.85)  LDD1576  [8]
 LDCM0373  CL104 HEK-293T C166(1.03); C12(1.08)  LDD1577  [8]
 LDCM0374  CL105 HEK-293T C12(0.89)  LDD1578  [8]
 LDCM0375  CL106 HEK-293T C166(0.99); C12(0.98)  LDD1579  [8]
 LDCM0376  CL107 HEK-293T C166(0.90); C12(0.93)  LDD1580  [8]
 LDCM0377  CL108 HEK-293T C166(1.10); C12(1.25)  LDD1581  [8]
 LDCM0378  CL109 HEK-293T C12(0.95)  LDD1582  [8]
 LDCM0379  CL11 PaTu 8988t C12(0.94)  LDD1258  [5]
 LDCM0380  CL110 HEK-293T C166(0.89); C12(1.01)  LDD1584  [8]
 LDCM0381  CL111 HEK-293T C166(0.92); C12(0.92)  LDD1585  [8]
 LDCM0382  CL112 HCT 116 C12(1.11)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C12(1.39)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C12(1.31)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C12(1.18)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C12(1.14)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C12(1.35)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C12(1.11)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C12(0.98)  LDD0706  [5]
 LDCM0390  CL12 PaTu 8988t C12(1.31)  LDD1269  [5]
 LDCM0391  CL120 HCT 116 C12(1.24)  LDD0708  [5]
 LDCM0392  CL121 PaTu 8988t C12(1.98)  LDD1271  [5]
 LDCM0393  CL122 PaTu 8988t C12(1.29)  LDD1272  [5]
 LDCM0394  CL123 PaTu 8988t C12(2.58)  LDD1273  [5]
 LDCM0395  CL124 PaTu 8988t C12(1.30)  LDD1274  [5]
 LDCM0396  CL125 HCT 116 C12(0.76)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C12(0.72)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C12(1.32)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C12(1.04)  LDD0716  [5]
 LDCM0400  CL13 PaTu 8988t C12(1.12)  LDD1279  [5]
 LDCM0401  CL14 PaTu 8988t C12(1.38)  LDD1280  [5]
 LDCM0402  CL15 PaTu 8988t C12(0.85)  LDD1281  [5]
 LDCM0403  CL16 HCT 116 C12(0.66)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C12(0.63)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C12(0.75)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C12(1.07)  LDD0723  [5]
 LDCM0407  CL2 PaTu 8988t C12(0.99)  LDD1286  [5]
 LDCM0408  CL20 HCT 116 C12(0.68)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C12(1.48)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C12(1.24)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C12(0.89)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C12(1.21)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C12(0.95)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C12(0.76)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C12(0.74)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C12(0.66)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C12(0.56)  LDD0734  [5]
 LDCM0418  CL3 PaTu 8988t C12(1.31)  LDD1297  [5]
 LDCM0419  CL30 HCT 116 C12(0.60)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C12(1.55)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C12(1.01)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C12(4.04)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C12(1.88)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C12(1.78)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C12(1.70)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C12(1.84)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C12(2.20)  LDD0745  [5]
 LDCM0429  CL4 PaTu 8988t C12(1.18)  LDD1308  [5]
 LDCM0430  CL40 HCT 116 C12(1.80)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C12(2.22)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C12(1.66)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C12(2.26)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C12(2.33)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C12(2.22)  LDD0752  [5]
 LDCM0436  CL46 HEK-293T C12(0.87)  LDD1640  [8]
 LDCM0437  CL47 HEK-293T C12(0.95)  LDD1641  [8]
 LDCM0438  CL48 HEK-293T C166(1.35); C12(0.91)  LDD1642  [8]
 LDCM0439  CL49 HEK-293T C12(0.80)  LDD1643  [8]
 LDCM0440  CL5 PaTu 8988t C12(1.46)  LDD1319  [5]
 LDCM0441  CL50 HEK-293T C166(0.98); C12(0.92)  LDD1645  [8]
 LDCM0443  CL52 HEK-293T C166(1.15); C12(1.06)  LDD1646  [8]
 LDCM0444  CL53 HEK-293T C166(1.19); C12(1.14)  LDD1647  [8]
 LDCM0445  CL54 HEK-293T C166(1.10); C12(0.73)  LDD1648  [8]
 LDCM0446  CL55 HEK-293T C166(1.04); C12(1.00)  LDD1649  [8]
 LDCM0447  CL56 HEK-293T C166(1.06); C12(1.15)  LDD1650  [8]
 LDCM0448  CL57 HEK-293T C12(0.93)  LDD1651  [8]
 LDCM0449  CL58 HEK-293T C12(0.95)  LDD1652  [8]
 LDCM0450  CL59 HEK-293T C12(1.07)  LDD1653  [8]
 LDCM0451  CL6 PaTu 8988t C12(1.06)  LDD1330  [5]
 LDCM0452  CL60 HEK-293T C166(1.09); C12(0.91)  LDD1655  [8]
 LDCM0453  CL61 HCT 116 C12(1.05)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C12(1.30)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C12(1.15)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C12(1.15)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C12(1.16)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C12(1.36)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C12(1.43)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C12(1.16)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C12(1.05)  LDD0778  [5]
 LDCM0462  CL7 PaTu 8988t C12(1.15)  LDD1341  [5]
 LDCM0463  CL70 HCT 116 C12(1.07)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C12(1.06)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C12(1.30)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C12(1.40)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C12(1.15)  LDD0784  [5]
 LDCM0469  CL76 PaTu 8988t C12(0.95)  LDD1348  [5]
 LDCM0470  CL77 PaTu 8988t C12(0.81)  LDD1349  [5]
 LDCM0471  CL78 PaTu 8988t C12(1.14)  LDD1350  [5]
 LDCM0472  CL79 PaTu 8988t C12(0.88)  LDD1351  [5]
 LDCM0473  CL8 PaTu 8988t C12(1.34)  LDD1352  [5]
 LDCM0474  CL80 PaTu 8988t C12(1.10)  LDD1353  [5]
 LDCM0475  CL81 PaTu 8988t C12(1.11)  LDD1354  [5]
 LDCM0476  CL82 PaTu 8988t C12(1.12)  LDD1355  [5]
 LDCM0477  CL83 PaTu 8988t C12(0.82)  LDD1356  [5]
 LDCM0478  CL84 PaTu 8988t C12(1.14)  LDD1357  [5]
 LDCM0479  CL85 PaTu 8988t C12(0.93)  LDD1358  [5]
 LDCM0480  CL86 PaTu 8988t C12(1.01)  LDD1359  [5]
 LDCM0481  CL87 PaTu 8988t C12(1.05)  LDD1360  [5]
 LDCM0482  CL88 PaTu 8988t C12(1.13)  LDD1361  [5]
 LDCM0483  CL89 PaTu 8988t C12(1.28)  LDD1362  [5]
 LDCM0484  CL9 PaTu 8988t C12(1.39)  LDD1363  [5]
 LDCM0485  CL90 PaTu 8988t C12(1.01)  LDD1364  [5]
 LDCM0486  CL91 PaTu 8988t C12(0.85)  LDD1365  [5]
 LDCM0487  CL92 PaTu 8988t C12(0.92)  LDD1366  [5]
 LDCM0488  CL93 PaTu 8988t C12(0.92)  LDD1367  [5]
 LDCM0489  CL94 PaTu 8988t C12(0.93)  LDD1368  [5]
 LDCM0490  CL95 PaTu 8988t C12(0.96)  LDD1369  [5]
 LDCM0491  CL96 PaTu 8988t C12(0.80)  LDD1370  [5]
 LDCM0492  CL97 PaTu 8988t C12(1.07)  LDD1371  [5]
 LDCM0493  CL98 PaTu 8988t C12(1.32)  LDD1372  [5]
 LDCM0494  CL99 PaTu 8988t C12(1.02)  LDD1373  [5]
 LDCM0495  E2913 HEK-293T C166(0.84); C12(0.95)  LDD1698  [8]
 LDCM0175  Ethacrynic acid HeLa C12(0.91); C12(0.83)  LDD2210  [4]
 LDCM0202  EV-93 T cell C12(6.66)  LDD0527  [9]
 LDCM0625  F8 Ramos C12(0.63)  LDD2187  [10]
 LDCM0573  Fragment11 Ramos C12(0.40)  LDD2190  [10]
 LDCM0574  Fragment12 Ramos C12(2.06)  LDD2191  [10]
 LDCM0575  Fragment13 Ramos C12(1.37)  LDD2192  [10]
 LDCM0576  Fragment14 Ramos C12(0.59)  LDD2193  [10]
 LDCM0580  Fragment21 Ramos C12(0.85)  LDD2195  [10]
 LDCM0582  Fragment23 Ramos C12(1.90)  LDD2196  [10]
 LDCM0578  Fragment27 Ramos C12(1.05)  LDD2197  [10]
 LDCM0586  Fragment28 Ramos C12(0.37)  LDD2198  [10]
 LDCM0588  Fragment30 Ramos C12(0.63)  LDD2199  [10]
 LDCM0589  Fragment31 Ramos C12(1.21)  LDD2200  [10]
 LDCM0468  Fragment33 HCT 116 C12(1.07)  LDD0785  [5]
 LDCM0596  Fragment38 Ramos C12(1.23)  LDD2203  [10]
 LDCM0427  Fragment51 HCT 116 C12(1.76)  LDD0744  [5]
 LDCM0610  Fragment52 Ramos C12(0.74)  LDD2204  [10]
 LDCM0614  Fragment56 Ramos C12(0.83)  LDD2205  [10]
 LDCM0569  Fragment7 Ramos C12(1.24)  LDD2186  [10]
 LDCM0179  JZ128 PC-3 N.A.  LDD0462  [2]
 LDCM0022  KB02 HEK-293T C12(0.95)  LDD1492  [8]
 LDCM0023  KB03 HEK-293T C12(0.86)  LDD1497  [8]
 LDCM0024  KB05 NALM-6 C12(3.21)  LDD3339  [11]
 LDCM0131  RA190 MM1.R C12(2.25)  LDD0304  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Diacylglycerol lipase-alpha (DAGLA) Lipase family Q9Y4D2
Androgen-dependent TFPI-regulating protein (ADTRP) AIG1 family Q96IZ2
Very long chain fatty acid elongase 4 (ELOVL4) ELO family Q9GZR5
Glutathione hydrolase 7 (GGT7) Gamma-glutamyltransferase family Q9UJ14
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (B3GAT1) Glycosyltransferase 43 family Q9P2W7
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) HIBADH-related family P31937
Peroxynitrite isomerase THAP4 (THAP4) Nitrobindin family Q8WY91
17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) Short-chain dehydrogenases/reductases (SDR) family Q7Z5P4
ADP-ribosylation factor-like protein 13B (ARL13B) Arf family Q3SXY8
Transporter and channel
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proton-coupled zinc antiporter SLC30A8 (SLC30A8) Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family Q8IWU4
LHFPL tetraspan subfamily member 5 protein (LHFPL5) LHFP family Q8TAF8
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
Membrane-spanning 4-domains subfamily A member 4A (MS4A4A) MS4A family Q96JQ5
Syntaxin-1A (STX1A) Syntaxin family Q16623
Transmembrane protein 106C (TMEM106C) TMEM106 family Q9BVX2
Urea transporter 2 (SLC14A2) Urea transporter family Q15849
Thioredoxin-related transmembrane protein 2 (TMX2) . Q9Y320
Transmembrane protein 174 (TMEM174) . Q8WUU8
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) BZIP family Q96BA8
DnaJ homolog subfamily C member 1 (DNAJC1) . Q96KC8
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Free fatty acid receptor 2 (FFAR2) G-protein coupled receptor 1 family O15552
Immunoglobulin
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Advanced glycosylation end product-specific receptor (AGER) . Q15109
B-cell antigen receptor complex-associated protein alpha chain (CD79A) . P11912
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) . Q02223
Other
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Calsyntenin-3 (CLSTN3) Calsyntenin family Q9BQT9
Membrane protein FAM174A (FAM174A) FAM174 family Q8TBP5
Protein FAM209A (FAM209A) FAM209 family Q5JX71
P antigen family member 1 (PAGE1) GAGE family O75459
RAB6-interacting golgin (GORAB) GORAB family Q5T7V8
Low-density lipoprotein receptor class A domain-containing protein 1 (LDLRAD1) LDLR family Q5T700
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) Proteasome subunit S10 family Q15008
Reticulophagy regulator 3 (RETREG3) RETREG family Q86VR2
Protein shisa-3 homolog (SHISA3) Shisa family A0PJX4
T-cell leukemia translocation-altered gene protein (TCTA) TCTA family P57738
Bcl-2-interacting killer (BIK) . Q13323
FERM domain-containing protein 3 (FRMD3) . A2A2Y4
PILR alpha-associated neural protein (PIANP) . Q8IYJ0
Serine-rich single-pass membrane protein 1 (SSMEM1) . Q8WWF3
Testis-expressed protein 29 (TEX29) . Q8N6K0

References

1 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.
2 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol Pharm. 2018 Jun 4;15(6):2413-2422. doi: 10.1021/acs.molpharmaceut.8b00250. Epub 2018 May 15.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
7 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
9 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
10 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
11 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840