Details of the Target

General Information of Target

Target ID LDTP01988
Target Name ATP synthase protein 8 (MT-ATP8)
Gene Name MT-ATP8
Gene ID 4509
Synonyms
ATP8; ATPASE8; MTATP8; ATP synthase protein 8; A6L; F-ATPase subunit 8
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPQLNTTVWPTMITPMLLTLFLITQLKMLNTNYHLPPSPKPMKMKNYNKPWEPKWTKICS
LHSLPPQS
Target Bioclass
Transporter and channel
Family
ATPase protein 8 family
Subcellular location
Mitochondrion membrane
Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Uniprot ID
P03928
Ensemble ID
ENST00000361851.1
HGNC ID
HGNC:7415

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 15 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TH211
 Probe Info  		Y47(7.71)  LDD0260  [1]
STPyne
 Probe Info  		K45(3.59); K49(9.03); K54(3.72)  LDD0277  [2]
EA-probe
 Probe Info  		C59(0.96)  LDD2210  [3]
DBIA
 Probe Info  		C59(1.06)  LDD1492  [4]
5E-2FA
 Probe Info  		N.A.  LDD2235  [5]
m-APA
 Probe Info  		H34(0.00); H62(0.00)  LDD2231  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [6]
ATP probe
 Probe Info  		K45(0.00); K49(0.00)  LDD0035  [7]
NAIA_5
 Probe Info  		N.A.  LDD2224  [8]
WYneO
 Probe Info  		N.A.  LDD0022  [9]
IPM
 Probe Info  		N.A.  LDD0005  [9]
PF-06672131
 Probe Info  		N.A.  LDD0152  [10]
SF
 Probe Info  		N.A.  LDD0028  [11]
Crotonaldehyde
 Probe Info  		C59(0.00); H62(0.00)  LDD0219  [12]
Methacrolein
 Probe Info  		N.A.  LDD0218  [12]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C59(1.10)  LDD1507  [4]
 LDCM0215  AC10 HEK-293T C59(1.05)  LDD1508  [4]
 LDCM0226  AC11 HEK-293T C59(1.03)  LDD1509  [4]
 LDCM0237  AC12 HEK-293T C59(1.06)  LDD1510  [4]
 LDCM0259  AC14 HEK-293T C59(1.10)  LDD1512  [4]
 LDCM0270  AC15 HEK-293T C59(1.00)  LDD1513  [4]
 LDCM0276  AC17 HEK-293T C59(1.10)  LDD1515  [4]
 LDCM0277  AC18 HEK-293T C59(0.95)  LDD1516  [4]
 LDCM0278  AC19 HEK-293T C59(0.89)  LDD1517  [4]
 LDCM0279  AC2 HEK-293T C59(1.10)  LDD1518  [4]
 LDCM0280  AC20 HEK-293T C59(1.07)  LDD1519  [4]
 LDCM0281  AC21 HEK-293T C59(1.00)  LDD1520  [4]
 LDCM0282  AC22 HEK-293T C59(1.06)  LDD1521  [4]
 LDCM0283  AC23 HEK-293T C59(1.09)  LDD1522  [4]
 LDCM0284  AC24 HEK-293T C59(1.00)  LDD1523  [4]
 LDCM0285  AC25 HEK-293T C59(1.15)  LDD1524  [4]
 LDCM0286  AC26 HEK-293T C59(1.03)  LDD1525  [4]
 LDCM0287  AC27 HEK-293T C59(0.97)  LDD1526  [4]
 LDCM0288  AC28 HEK-293T C59(1.05)  LDD1527  [4]
 LDCM0289  AC29 HEK-293T C59(1.01)  LDD1528  [4]
 LDCM0290  AC3 HEK-293T C59(0.96)  LDD1529  [4]
 LDCM0291  AC30 HEK-293T C59(1.06)  LDD1530  [4]
 LDCM0292  AC31 HEK-293T C59(1.02)  LDD1531  [4]
 LDCM0293  AC32 HEK-293T C59(0.97)  LDD1532  [4]
 LDCM0294  AC33 HEK-293T C59(1.23)  LDD1533  [4]
 LDCM0295  AC34 HEK-293T C59(1.03)  LDD1534  [4]
 LDCM0296  AC35 HEK-293T C59(1.06)  LDD1535  [4]
 LDCM0297  AC36 HEK-293T C59(1.20)  LDD1536  [4]
 LDCM0298  AC37 HEK-293T C59(1.04)  LDD1537  [4]
 LDCM0299  AC38 HEK-293T C59(1.14)  LDD1538  [4]
 LDCM0300  AC39 HEK-293T C59(1.07)  LDD1539  [4]
 LDCM0301  AC4 HEK-293T C59(1.02)  LDD1540  [4]
 LDCM0302  AC40 HEK-293T C59(0.99)  LDD1541  [4]
 LDCM0303  AC41 HEK-293T C59(1.23)  LDD1542  [4]
 LDCM0304  AC42 HEK-293T C59(1.00)  LDD1543  [4]
 LDCM0305  AC43 HEK-293T C59(0.93)  LDD1544  [4]
 LDCM0306  AC44 HEK-293T C59(1.11)  LDD1545  [4]
 LDCM0307  AC45 HEK-293T C59(1.02)  LDD1546  [4]
 LDCM0308  AC46 HEK-293T C59(1.04)  LDD1547  [4]
 LDCM0309  AC47 HEK-293T C59(1.05)  LDD1548  [4]
 LDCM0310  AC48 HEK-293T C59(1.02)  LDD1549  [4]
 LDCM0311  AC49 HEK-293T C59(1.12)  LDD1550  [4]
 LDCM0312  AC5 HEK-293T C59(1.08)  LDD1551  [4]
 LDCM0313  AC50 HEK-293T C59(0.94)  LDD1552  [4]
 LDCM0314  AC51 HEK-293T C59(1.06)  LDD1553  [4]
 LDCM0315  AC52 HEK-293T C59(1.14)  LDD1554  [4]
 LDCM0316  AC53 HEK-293T C59(0.99)  LDD1555  [4]
 LDCM0317  AC54 HEK-293T C59(1.11)  LDD1556  [4]
 LDCM0318  AC55 HEK-293T C59(1.06)  LDD1557  [4]
 LDCM0319  AC56 HEK-293T C59(1.01)  LDD1558  [4]
 LDCM0320  AC57 HEK-293T C59(1.18)  LDD1559  [4]
 LDCM0321  AC58 HEK-293T C59(0.98)  LDD1560  [4]
 LDCM0322  AC59 HEK-293T C59(1.00)  LDD1561  [4]
 LDCM0323  AC6 HEK-293T C59(1.03)  LDD1562  [4]
 LDCM0324  AC60 HEK-293T C59(1.16)  LDD1563  [4]
 LDCM0325  AC61 HEK-293T C59(1.03)  LDD1564  [4]
 LDCM0326  AC62 HEK-293T C59(1.14)  LDD1565  [4]
 LDCM0327  AC63 HEK-293T C59(1.11)  LDD1566  [4]
 LDCM0328  AC64 HEK-293T C59(0.99)  LDD1567  [4]
 LDCM0334  AC7 HEK-293T C59(1.02)  LDD1568  [4]
 LDCM0345  AC8 HEK-293T C59(1.00)  LDD1569  [4]
 LDCM0248  AKOS034007472 HEK-293T C59(0.97)  LDD1511  [4]
 LDCM0356  AKOS034007680 HEK-293T C59(1.17)  LDD1570  [4]
 LDCM0275  AKOS034007705 HEK-293T C59(1.02)  LDD1514  [4]
 LDCM0367  CL1 HEK-293T C59(1.06)  LDD1571  [4]
 LDCM0368  CL10 HEK-293T C59(1.17)  LDD1572  [4]
 LDCM0369  CL100 HEK-293T C59(1.01)  LDD1573  [4]
 LDCM0370  CL101 HEK-293T C59(1.14)  LDD1574  [4]
 LDCM0371  CL102 HEK-293T C59(1.08)  LDD1575  [4]
 LDCM0372  CL103 HEK-293T C59(1.00)  LDD1576  [4]
 LDCM0373  CL104 HEK-293T C59(0.95)  LDD1577  [4]
 LDCM0374  CL105 HEK-293T C59(1.00)  LDD1578  [4]
 LDCM0375  CL106 HEK-293T C59(0.95)  LDD1579  [4]
 LDCM0376  CL107 HEK-293T C59(0.95)  LDD1580  [4]
 LDCM0377  CL108 HEK-293T C59(0.93)  LDD1581  [4]
 LDCM0378  CL109 HEK-293T C59(0.98)  LDD1582  [4]
 LDCM0379  CL11 HEK-293T C59(0.99)  LDD1583  [4]
 LDCM0380  CL110 HEK-293T C59(0.98)  LDD1584  [4]
 LDCM0381  CL111 HEK-293T C59(0.94)  LDD1585  [4]
 LDCM0382  CL112 HEK-293T C59(0.99)  LDD1586  [4]
 LDCM0383  CL113 HEK-293T C59(1.10)  LDD1587  [4]
 LDCM0384  CL114 HEK-293T C59(1.02)  LDD1588  [4]
 LDCM0385  CL115 HEK-293T C59(0.98)  LDD1589  [4]
 LDCM0386  CL116 HEK-293T C59(1.02)  LDD1590  [4]
 LDCM0387  CL117 HEK-293T C59(1.06)  LDD1591  [4]
 LDCM0388  CL118 HEK-293T C59(1.00)  LDD1592  [4]
 LDCM0389  CL119 HEK-293T C59(1.07)  LDD1593  [4]
 LDCM0390  CL12 HEK-293T C59(0.97)  LDD1594  [4]
 LDCM0391  CL120 HEK-293T C59(1.13)  LDD1595  [4]
 LDCM0392  CL121 HEK-293T C59(1.00)  LDD1596  [4]
 LDCM0393  CL122 HEK-293T C59(1.04)  LDD1597  [4]
 LDCM0394  CL123 HEK-293T C59(1.02)  LDD1598  [4]
 LDCM0395  CL124 HEK-293T C59(0.92)  LDD1599  [4]
 LDCM0396  CL125 HEK-293T C59(0.96)  LDD1600  [4]
 LDCM0397  CL126 HEK-293T C59(0.95)  LDD1601  [4]
 LDCM0398  CL127 HEK-293T C59(0.95)  LDD1602  [4]
 LDCM0399  CL128 HEK-293T C59(1.01)  LDD1603  [4]
 LDCM0400  CL13 HEK-293T C59(1.02)  LDD1604  [4]
 LDCM0401  CL14 HEK-293T C59(1.06)  LDD1605  [4]
 LDCM0402  CL15 HEK-293T C59(1.02)  LDD1606  [4]
 LDCM0403  CL16 HEK-293T C59(1.05)  LDD1607  [4]
 LDCM0404  CL17 HEK-293T C59(1.08)  LDD1608  [4]
 LDCM0405  CL18 HEK-293T C59(0.99)  LDD1609  [4]
 LDCM0406  CL19 HEK-293T C59(0.94)  LDD1610  [4]
 LDCM0407  CL2 HEK-293T C59(1.12)  LDD1611  [4]
 LDCM0408  CL20 HEK-293T C59(0.97)  LDD1612  [4]
 LDCM0409  CL21 HEK-293T C59(0.88)  LDD1613  [4]
 LDCM0410  CL22 HEK-293T C59(0.94)  LDD1614  [4]
 LDCM0411  CL23 HEK-293T C59(0.92)  LDD1615  [4]
 LDCM0412  CL24 HEK-293T C59(1.00)  LDD1616  [4]
 LDCM0413  CL25 HEK-293T C59(1.06)  LDD1617  [4]
 LDCM0414  CL26 HEK-293T C59(1.02)  LDD1618  [4]
 LDCM0415  CL27 HEK-293T C59(0.92)  LDD1619  [4]
 LDCM0416  CL28 HEK-293T C59(0.96)  LDD1620  [4]
 LDCM0417  CL29 HEK-293T C59(1.00)  LDD1621  [4]
 LDCM0418  CL3 HEK-293T C59(1.11)  LDD1622  [4]
 LDCM0419  CL30 HEK-293T C59(0.79)  LDD1623  [4]
 LDCM0420  CL31 HEK-293T C59(0.78)  LDD1624  [4]
 LDCM0421  CL32 HEK-293T C59(0.88)  LDD1625  [4]
 LDCM0422  CL33 HEK-293T C59(0.79)  LDD1626  [4]
 LDCM0423  CL34 HEK-293T C59(0.97)  LDD1627  [4]
 LDCM0424  CL35 HEK-293T C59(0.88)  LDD1628  [4]
 LDCM0425  CL36 HEK-293T C59(1.00)  LDD1629  [4]
 LDCM0426  CL37 HEK-293T C59(1.04)  LDD1630  [4]
 LDCM0428  CL39 HEK-293T C59(1.09)  LDD1632  [4]
 LDCM0429  CL4 HEK-293T C59(0.96)  LDD1633  [4]
 LDCM0430  CL40 HEK-293T C59(1.01)  LDD1634  [4]
 LDCM0431  CL41 HEK-293T C59(1.01)  LDD1635  [4]
 LDCM0432  CL42 HEK-293T C59(0.89)  LDD1636  [4]
 LDCM0433  CL43 HEK-293T C59(1.01)  LDD1637  [4]
 LDCM0434  CL44 HEK-293T C59(0.99)  LDD1638  [4]
 LDCM0435  CL45 HEK-293T C59(0.87)  LDD1639  [4]
 LDCM0436  CL46 HEK-293T C59(1.11)  LDD1640  [4]
 LDCM0437  CL47 HEK-293T C59(0.87)  LDD1641  [4]
 LDCM0438  CL48 HEK-293T C59(1.04)  LDD1642  [4]
 LDCM0439  CL49 HEK-293T C59(0.96)  LDD1643  [4]
 LDCM0440  CL5 HEK-293T C59(1.00)  LDD1644  [4]
 LDCM0441  CL50 HEK-293T C59(0.99)  LDD1645  [4]
 LDCM0443  CL52 HEK-293T C59(0.96)  LDD1646  [4]
 LDCM0444  CL53 HEK-293T C59(1.16)  LDD1647  [4]
 LDCM0445  CL54 HEK-293T C59(0.82)  LDD1648  [4]
 LDCM0446  CL55 HEK-293T C59(0.94)  LDD1649  [4]
 LDCM0447  CL56 HEK-293T C59(1.04)  LDD1650  [4]
 LDCM0448  CL57 HEK-293T C59(0.83)  LDD1651  [4]
 LDCM0449  CL58 HEK-293T C59(0.99)  LDD1652  [4]
 LDCM0450  CL59 HEK-293T C59(0.91)  LDD1653  [4]
 LDCM0451  CL6 HEK-293T C59(1.06)  LDD1654  [4]
 LDCM0452  CL60 HEK-293T C59(1.12)  LDD1655  [4]
 LDCM0453  CL61 HEK-293T C59(1.09)  LDD1656  [4]
 LDCM0454  CL62 HEK-293T C59(1.09)  LDD1657  [4]
 LDCM0455  CL63 HEK-293T C59(1.02)  LDD1658  [4]
 LDCM0456  CL64 HEK-293T C59(1.02)  LDD1659  [4]
 LDCM0457  CL65 HEK-293T C59(1.14)  LDD1660  [4]
 LDCM0458  CL66 HEK-293T C59(0.92)  LDD1661  [4]
 LDCM0459  CL67 HEK-293T C59(0.88)  LDD1662  [4]
 LDCM0460  CL68 HEK-293T C59(0.95)  LDD1663  [4]
 LDCM0461  CL69 HEK-293T C59(0.86)  LDD1664  [4]
 LDCM0462  CL7 HEK-293T C59(1.09)  LDD1665  [4]
 LDCM0463  CL70 HEK-293T C59(1.05)  LDD1666  [4]
 LDCM0464  CL71 HEK-293T C59(1.01)  LDD1667  [4]
 LDCM0465  CL72 HEK-293T C59(1.10)  LDD1668  [4]
 LDCM0466  CL73 HEK-293T C59(1.05)  LDD1669  [4]
 LDCM0467  CL74 HEK-293T C59(1.03)  LDD1670  [4]
 LDCM0469  CL76 HEK-293T C59(0.99)  LDD1672  [4]
 LDCM0470  CL77 HEK-293T C59(0.99)  LDD1673  [4]
 LDCM0471  CL78 HEK-293T C59(0.84)  LDD1674  [4]
 LDCM0472  CL79 HEK-293T C59(0.77)  LDD1675  [4]
 LDCM0473  CL8 HEK-293T C59(0.91)  LDD1676  [4]
 LDCM0474  CL80 HEK-293T C59(0.93)  LDD1677  [4]
 LDCM0475  CL81 HEK-293T C59(0.92)  LDD1678  [4]
 LDCM0476  CL82 HEK-293T C59(0.98)  LDD1679  [4]
 LDCM0477  CL83 HEK-293T C59(0.96)  LDD1680  [4]
 LDCM0478  CL84 HEK-293T C59(0.97)  LDD1681  [4]
 LDCM0479  CL85 HEK-293T C59(1.11)  LDD1682  [4]
 LDCM0480  CL86 HEK-293T C59(0.97)  LDD1683  [4]
 LDCM0481  CL87 HEK-293T C59(0.91)  LDD1684  [4]
 LDCM0482  CL88 HEK-293T C59(1.02)  LDD1685  [4]
 LDCM0483  CL89 HEK-293T C59(1.08)  LDD1686  [4]
 LDCM0484  CL9 HEK-293T C59(0.83)  LDD1687  [4]
 LDCM0485  CL90 HEK-293T C59(1.16)  LDD1688  [4]
 LDCM0486  CL91 HEK-293T C59(0.85)  LDD1689  [4]
 LDCM0487  CL92 HEK-293T C59(1.10)  LDD1690  [4]
 LDCM0488  CL93 HEK-293T C59(0.92)  LDD1691  [4]
 LDCM0489  CL94 HEK-293T C59(1.04)  LDD1692  [4]
 LDCM0490  CL95 HEK-293T C59(0.94)  LDD1693  [4]
 LDCM0491  CL96 HEK-293T C59(0.94)  LDD1694  [4]
 LDCM0492  CL97 HEK-293T C59(1.07)  LDD1695  [4]
 LDCM0493  CL98 HEK-293T C59(1.00)  LDD1696  [4]
 LDCM0494  CL99 HEK-293T C59(0.97)  LDD1697  [4]
 LDCM0495  E2913 HEK-293T C59(1.11)  LDD1698  [4]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C59(3.60)  LDD1702  [13]
 LDCM0175  Ethacrynic acid HeLa C59(0.96)  LDD2210  [3]
 LDCM0625  F8 Ramos C59(1.50)  LDD2187  [14]
 LDCM0572  Fragment10 Ramos C59(0.88)  LDD2189  [14]
 LDCM0573  Fragment11 Ramos C59(0.00)  LDD2190  [14]
 LDCM0574  Fragment12 Ramos C59(1.32)  LDD2191  [14]
 LDCM0575  Fragment13 Ramos C59(1.73)  LDD2192  [14]
 LDCM0576  Fragment14 Ramos C59(3.55)  LDD2193  [14]
 LDCM0579  Fragment20 Ramos C59(1.95)  LDD2194  [14]
 LDCM0580  Fragment21 Ramos C59(0.84)  LDD2195  [14]
 LDCM0582  Fragment23 Ramos C59(0.66)  LDD2196  [14]
 LDCM0578  Fragment27 Ramos C59(0.85)  LDD2197  [14]
 LDCM0586  Fragment28 Ramos C59(0.54)  LDD2198  [14]
 LDCM0588  Fragment30 Ramos C59(0.72)  LDD2199  [14]
 LDCM0589  Fragment31 Ramos C59(1.29)  LDD2200  [14]
 LDCM0590  Fragment32 Ramos C59(1.11)  LDD2201  [14]
 LDCM0468  Fragment33 HEK-293T C59(0.96)  LDD1671  [4]
 LDCM0596  Fragment38 Ramos C59(1.39)  LDD2203  [14]
 LDCM0566  Fragment4 Ramos C59(1.96)  LDD2184  [14]
 LDCM0427  Fragment51 HEK-293T C59(1.06)  LDD1631  [4]
 LDCM0610  Fragment52 Ramos C59(0.70)  LDD2204  [14]
 LDCM0614  Fragment56 Ramos C59(0.71)  LDD2205  [14]
 LDCM0569  Fragment7 Ramos C59(1.46)  LDD2186  [14]
 LDCM0571  Fragment9 Ramos C59(1.69)  LDD2188  [14]
 LDCM0022  KB02 HEK-293T C59(1.06)  LDD1492  [4]
 LDCM0023  KB03 HEK-293T C59(1.14)  LDD1497  [4]
 LDCM0024  KB05 HEK-293T C59(1.03)  LDD1502  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C59(1.08)  LDD2206  [15]
 LDCM0628  OTUB2-COV-1 HEK-293T C59(0.88)  LDD2207  [15]

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol Pharm. 2018 Jun 4;15(6):2413-2422. doi: 10.1021/acs.molpharmaceut.8b00250. Epub 2018 May 15.
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
5 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
10 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
11 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
12 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
13 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
14 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
15 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.