Details of the Target

General Information of Target

Target ID LDTP10519
Target Name Protein FAM210B, mitochondrial (FAM210B)
Gene Name FAM210B
Gene ID 116151
Synonyms
C20orf108; Protein FAM210B, mitochondrial
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAEWGGGVGYSGSGPGRSRWRWSGSVWVRSVLLLLGGLRASATSTPVSLGSSPPCRHHV
PSDTEVINKVHLKANHVVKRDVDEHLRIKTVYDKSVEELLPEKKNLVKNKLFPQAISYLE
KTFQVRRPAGTILLSRQCATNQYLRKENDPHRYCTGECAAHTKCGPVIVPEEHLQQCRVY
RGGKWPHGAVGVPDQEGISDADFVLYVGALATERCSHENIISYAAYCQQEANMDRPIAGY
ANLCPNMISTQPQEFVGMLSTVKHEVIHALGFSAGLFAFYHDKDGNPLTSRFADGLPPFN
YSLGLYQWSDKVVRKVERLWDVRDNKIVRHTVYLLVTPRVVEEARKHFDCPVLEGMELEN
QGGVGTELNHWEKRLLENEAMTGSHTQNRVLSRITLALMEDTGRQMLSPYCDTLRSNPLQ
LTCRQDQRAVAVCNLQKFPKPLPQEYQYFDELSGIPAEDLPYYGGSVEIADYCPFSQEFS
WHLSGEYQRSSDCRILENQPEIFKNYGAEKYGPHSVCLIQKSAFVMEKCERKLSYPDWGS
GCYQVSCSPQGLKVWVQDTSYLCSRAGQVLPVSIQMNGWIHDGNLLCPSCWDFCELCPPE
TDPPATNLTRALPLDLCSCSSSLVVTLWLLLGNLFPLLAGFLLCIWH
Target Bioclass
Other
Family
FAM210 family
Subcellular location
Mitochondrion
Function Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner.
Uniprot ID
Q96KR6
Ensemble ID
ENST00000371384.4
HGNC ID
HGNC:16102

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
JZ128-DTB
 Probe Info  		N.A.  LDD0462  [2]
BTD
 Probe Info  		C77(0.84)  LDD2125  [3]
DBIA
 Probe Info  		C77(1.42)  LDD0080  [4]
NAIA_4
 Probe Info  		N.A.  LDD2226  [5]
WYneN
 Probe Info  		N.A.  LDD0021  [6]
PPMS
 Probe Info  		N.A.  LDD0008  [6]
VSF
 Probe Info  		N.A.  LDD0007  [6]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [7]
Methacrolein
 Probe Info  		N.A.  LDD0218  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C77(0.95)  LDD0812  [4]
 LDCM0215  AC10 HEK-293T C77(0.79)  LDD0813  [4]
 LDCM0216  AC100 HEK-293T C77(0.92)  LDD0814  [4]
 LDCM0217  AC101 HEK-293T C77(1.22)  LDD0815  [4]
 LDCM0218  AC102 HEK-293T C77(1.00)  LDD0816  [4]
 LDCM0219  AC103 HEK-293T C77(1.01)  LDD0817  [4]
 LDCM0220  AC104 HEK-293T C77(0.90)  LDD0818  [4]
 LDCM0221  AC105 HEK-293T C77(0.88)  LDD0819  [4]
 LDCM0222  AC106 HEK-293T C77(1.12)  LDD0820  [4]
 LDCM0223  AC107 HEK-293T C77(0.95)  LDD0821  [4]
 LDCM0224  AC108 HEK-293T C77(0.89)  LDD0822  [4]
 LDCM0225  AC109 HEK-293T C77(0.95)  LDD0823  [4]
 LDCM0226  AC11 HEK-293T C77(0.93)  LDD0824  [4]
 LDCM0227  AC110 HEK-293T C77(1.37)  LDD0825  [4]
 LDCM0228  AC111 HEK-293T C77(2.44)  LDD0826  [4]
 LDCM0229  AC112 HEK-293T C77(1.94)  LDD0827  [4]
 LDCM0230  AC113 HEK-293T C77(0.98)  LDD0828  [4]
 LDCM0231  AC114 HEK-293T C77(1.04)  LDD0829  [4]
 LDCM0232  AC115 HEK-293T C77(1.02)  LDD0830  [4]
 LDCM0233  AC116 HEK-293T C77(0.95)  LDD0831  [4]
 LDCM0234  AC117 HEK-293T C77(0.98)  LDD0832  [4]
 LDCM0235  AC118 HEK-293T C77(1.00)  LDD0833  [4]
 LDCM0236  AC119 HEK-293T C77(1.02)  LDD0834  [4]
 LDCM0237  AC12 HEK-293T C77(1.04)  LDD0835  [4]
 LDCM0238  AC120 HEK-293T C77(1.23)  LDD0836  [4]
 LDCM0239  AC121 HEK-293T C77(1.07)  LDD0837  [4]
 LDCM0240  AC122 HEK-293T C77(1.42)  LDD0838  [4]
 LDCM0241  AC123 HEK-293T C77(1.42)  LDD0839  [4]
 LDCM0242  AC124 HEK-293T C77(1.04)  LDD0840  [4]
 LDCM0243  AC125 HEK-293T C77(1.22)  LDD0841  [4]
 LDCM0244  AC126 HEK-293T C77(2.00)  LDD0842  [4]
 LDCM0245  AC127 HEK-293T C77(2.50)  LDD0843  [4]
 LDCM0246  AC128 HEK-293T C77(1.39)  LDD0844  [4]
 LDCM0247  AC129 HEK-293T C77(0.87)  LDD0845  [4]
 LDCM0249  AC130 HEK-293T C77(0.88)  LDD0847  [4]
 LDCM0250  AC131 HEK-293T C77(1.10)  LDD0848  [4]
 LDCM0251  AC132 HEK-293T C77(0.94)  LDD0849  [4]
 LDCM0252  AC133 HEK-293T C77(0.82)  LDD0850  [4]
 LDCM0253  AC134 HEK-293T C77(0.81)  LDD0851  [4]
 LDCM0254  AC135 HEK-293T C77(0.76)  LDD0852  [4]
 LDCM0255  AC136 HEK-293T C77(0.74)  LDD0853  [4]
 LDCM0256  AC137 HEK-293T C77(0.86)  LDD0854  [4]
 LDCM0257  AC138 HEK-293T C77(0.86)  LDD0855  [4]
 LDCM0258  AC139 HEK-293T C77(0.69)  LDD0856  [4]
 LDCM0259  AC14 HEK-293T C77(0.74)  LDD0857  [4]
 LDCM0260  AC140 HEK-293T C77(0.79)  LDD0858  [4]
 LDCM0261  AC141 HEK-293T C77(0.69)  LDD0859  [4]
 LDCM0262  AC142 HEK-293T C77(0.79)  LDD0860  [4]
 LDCM0263  AC143 HEK-293T C77(1.22)  LDD0861  [4]
 LDCM0264  AC144 HEK-293T C77(1.52)  LDD0862  [4]
 LDCM0265  AC145 HEK-293T C77(1.49)  LDD0863  [4]
 LDCM0266  AC146 HEK-293T C77(1.65)  LDD0864  [4]
 LDCM0267  AC147 HEK-293T C77(1.90)  LDD0865  [4]
 LDCM0268  AC148 HEK-293T C77(1.40)  LDD0866  [4]
 LDCM0269  AC149 HEK-293T C77(1.08)  LDD0867  [4]
 LDCM0270  AC15 HEK-293T C77(0.68)  LDD0868  [4]
 LDCM0271  AC150 HEK-293T C77(1.15)  LDD0869  [4]
 LDCM0272  AC151 HEK-293T C77(1.00)  LDD0870  [4]
 LDCM0273  AC152 HEK-293T C77(1.04)  LDD0871  [4]
 LDCM0274  AC153 HEK-293T C77(1.28)  LDD0872  [4]
 LDCM0621  AC154 HEK-293T C77(1.07)  LDD2162  [4]
 LDCM0622  AC155 HEK-293T C77(1.09)  LDD2163  [4]
 LDCM0623  AC156 HEK-293T C77(1.69)  LDD2164  [4]
 LDCM0624  AC157 HEK-293T C77(2.26)  LDD2165  [4]
 LDCM0276  AC17 HEK-293T C77(0.49)  LDD0874  [4]
 LDCM0277  AC18 HEK-293T C77(0.59)  LDD0875  [4]
 LDCM0278  AC19 HEK-293T C77(0.56)  LDD0876  [4]
 LDCM0279  AC2 HEK-293T C77(0.53)  LDD0877  [4]
 LDCM0280  AC20 HEK-293T C77(0.39)  LDD0878  [4]
 LDCM0281  AC21 HEK-293T C77(0.49)  LDD0879  [4]
 LDCM0282  AC22 HEK-293T C77(0.45)  LDD0880  [4]
 LDCM0283  AC23 HEK-293T C77(0.41)  LDD0881  [4]
 LDCM0284  AC24 HEK-293T C77(0.54)  LDD0882  [4]
 LDCM0285  AC25 HEK-293T C77(0.64)  LDD0883  [4]
 LDCM0286  AC26 HEK-293T C77(0.82)  LDD0884  [4]
 LDCM0287  AC27 HEK-293T C77(0.71)  LDD0885  [4]
 LDCM0288  AC28 HEK-293T C77(0.87)  LDD0886  [4]
 LDCM0289  AC29 HEK-293T C77(0.83)  LDD0887  [4]
 LDCM0290  AC3 HEK-293T C77(0.82)  LDD0888  [4]
 LDCM0291  AC30 HEK-293T C77(0.72)  LDD0889  [4]
 LDCM0292  AC31 HEK-293T C77(0.82)  LDD0890  [4]
 LDCM0293  AC32 HEK-293T C77(0.79)  LDD0891  [4]
 LDCM0294  AC33 HEK-293T C77(0.73)  LDD0892  [4]
 LDCM0295  AC34 HEK-293T C77(0.87)  LDD0893  [4]
 LDCM0296  AC35 HEK-293T C77(0.88)  LDD0894  [4]
 LDCM0297  AC36 HEK-293T C77(0.76)  LDD0895  [4]
 LDCM0298  AC37 HEK-293T C77(0.75)  LDD0896  [4]
 LDCM0299  AC38 HEK-293T C77(0.76)  LDD0897  [4]
 LDCM0300  AC39 HEK-293T C77(0.79)  LDD0898  [4]
 LDCM0301  AC4 HEK-293T C77(0.77)  LDD0899  [4]
 LDCM0302  AC40 HEK-293T C77(0.82)  LDD0900  [4]
 LDCM0303  AC41 HEK-293T C77(0.92)  LDD0901  [4]
 LDCM0304  AC42 HEK-293T C77(0.77)  LDD0902  [4]
 LDCM0305  AC43 HEK-293T C77(0.63)  LDD0903  [4]
 LDCM0306  AC44 HEK-293T C77(0.70)  LDD0904  [4]
 LDCM0307  AC45 HEK-293T C77(0.79)  LDD0905  [4]
 LDCM0308  AC46 HEK-293T C77(0.80)  LDD0906  [4]
 LDCM0309  AC47 HEK-293T C77(0.77)  LDD0907  [4]
 LDCM0310  AC48 HEK-293T C77(0.77)  LDD0908  [4]
 LDCM0311  AC49 HEK-293T C77(0.67)  LDD0909  [4]
 LDCM0312  AC5 HEK-293T C77(0.65)  LDD0910  [4]
 LDCM0313  AC50 HEK-293T C77(0.69)  LDD0911  [4]
 LDCM0314  AC51 HEK-293T C77(0.57)  LDD0912  [4]
 LDCM0315  AC52 HEK-293T C77(0.54)  LDD0913  [4]
 LDCM0316  AC53 HEK-293T C77(0.68)  LDD0914  [4]
 LDCM0317  AC54 HEK-293T C77(0.53)  LDD0915  [4]
 LDCM0318  AC55 HEK-293T C77(0.61)  LDD0916  [4]
 LDCM0319  AC56 HEK-293T C77(0.63)  LDD0917  [4]
 LDCM0320  AC57 HEK-293T C77(1.24)  LDD0918  [4]
 LDCM0321  AC58 HEK-293T C77(1.19)  LDD0919  [4]
 LDCM0322  AC59 HEK-293T C77(1.47)  LDD0920  [4]
 LDCM0323  AC6 HEK-293T C77(1.11)  LDD0921  [4]
 LDCM0324  AC60 HEK-293T C77(2.05)  LDD0922  [4]
 LDCM0325  AC61 HEK-293T C77(0.75)  LDD0923  [4]
 LDCM0326  AC62 HEK-293T C77(1.11)  LDD0924  [4]
 LDCM0327  AC63 HEK-293T C77(0.81)  LDD0925  [4]
 LDCM0328  AC64 HEK-293T C77(1.08)  LDD0926  [4]
 LDCM0329  AC65 HEK-293T C77(0.80)  LDD0927  [4]
 LDCM0330  AC66 HEK-293T C77(1.22)  LDD0928  [4]
 LDCM0331  AC67 HEK-293T C77(1.00)  LDD0929  [4]
 LDCM0332  AC68 HEK-293T C77(0.78)  LDD0930  [4]
 LDCM0333  AC69 HEK-293T C77(0.94)  LDD0931  [4]
 LDCM0334  AC7 HEK-293T C77(0.81)  LDD0932  [4]
 LDCM0335  AC70 HEK-293T C77(0.97)  LDD0933  [4]
 LDCM0336  AC71 HEK-293T C77(0.82)  LDD0934  [4]
 LDCM0337  AC72 HEK-293T C77(0.93)  LDD0935  [4]
 LDCM0338  AC73 HEK-293T C77(0.79)  LDD0936  [4]
 LDCM0339  AC74 HEK-293T C77(0.78)  LDD0937  [4]
 LDCM0340  AC75 HEK-293T C77(0.78)  LDD0938  [4]
 LDCM0341  AC76 HEK-293T C77(0.80)  LDD0939  [4]
 LDCM0342  AC77 HEK-293T C77(0.86)  LDD0940  [4]
 LDCM0343  AC78 HEK-293T C77(0.87)  LDD0941  [4]
 LDCM0344  AC79 HEK-293T C77(0.99)  LDD0942  [4]
 LDCM0345  AC8 HEK-293T C77(0.87)  LDD0943  [4]
 LDCM0346  AC80 HEK-293T C77(0.71)  LDD0944  [4]
 LDCM0347  AC81 HEK-293T C77(0.83)  LDD0945  [4]
 LDCM0348  AC82 HEK-293T C77(0.82)  LDD0946  [4]
 LDCM0349  AC83 HEK-293T C77(1.01)  LDD0947  [4]
 LDCM0350  AC84 HEK-293T C77(1.08)  LDD0948  [4]
 LDCM0351  AC85 HEK-293T C77(1.07)  LDD0949  [4]
 LDCM0352  AC86 HEK-293T C77(0.89)  LDD0950  [4]
 LDCM0353  AC87 HEK-293T C77(0.93)  LDD0951  [4]
 LDCM0354  AC88 HEK-293T C77(0.98)  LDD0952  [4]
 LDCM0355  AC89 HEK-293T C77(1.43)  LDD0953  [4]
 LDCM0357  AC90 HEK-293T C77(0.83)  LDD0955  [4]
 LDCM0358  AC91 HEK-293T C77(1.22)  LDD0956  [4]
 LDCM0359  AC92 HEK-293T C77(1.13)  LDD0957  [4]
 LDCM0360  AC93 HEK-293T C77(1.11)  LDD0958  [4]
 LDCM0361  AC94 HEK-293T C77(0.98)  LDD0959  [4]
 LDCM0362  AC95 HEK-293T C77(1.00)  LDD0960  [4]
 LDCM0363  AC96 HEK-293T C77(1.21)  LDD0961  [4]
 LDCM0364  AC97 HEK-293T C77(2.45)  LDD0962  [4]
 LDCM0365  AC98 HEK-293T C77(0.93)  LDD0963  [4]
 LDCM0366  AC99 HEK-293T C77(1.03)  LDD0964  [4]
 LDCM0248  AKOS034007472 HEK-293T C77(0.75)  LDD0846  [4]
 LDCM0356  AKOS034007680 HEK-293T C77(0.76)  LDD0954  [4]
 LDCM0275  AKOS034007705 HEK-293T C77(0.73)  LDD0873  [4]
 LDCM0632  CL-Sc Hep-G2 C77(0.46)  LDD2227  [5]
 LDCM0367  CL1 HEK-293T C77(0.80)  LDD0965  [4]
 LDCM0368  CL10 HEK-293T C77(0.32)  LDD0966  [4]
 LDCM0369  CL100 HEK-293T C77(0.49)  LDD0967  [4]
 LDCM0370  CL101 HEK-293T C77(0.89)  LDD0968  [4]
 LDCM0371  CL102 HEK-293T C77(0.84)  LDD0969  [4]
 LDCM0372  CL103 HEK-293T C77(0.70)  LDD0970  [4]
 LDCM0373  CL104 HEK-293T C77(0.72)  LDD0971  [4]
 LDCM0374  CL105 HEK-293T C77(0.81)  LDD0972  [4]
 LDCM0375  CL106 HEK-293T C77(0.65)  LDD0973  [4]
 LDCM0376  CL107 HEK-293T C77(0.74)  LDD0974  [4]
 LDCM0377  CL108 HEK-293T C77(0.66)  LDD0975  [4]
 LDCM0378  CL109 HEK-293T C77(0.67)  LDD0976  [4]
 LDCM0379  CL11 HEK-293T C77(0.30)  LDD0977  [4]
 LDCM0380  CL110 HEK-293T C77(0.54)  LDD0978  [4]
 LDCM0381  CL111 HEK-293T C77(0.81)  LDD0979  [4]
 LDCM0382  CL112 HEK-293T C77(0.84)  LDD0980  [4]
 LDCM0383  CL113 HEK-293T C77(0.80)  LDD0981  [4]
 LDCM0384  CL114 HEK-293T C77(0.81)  LDD0982  [4]
 LDCM0385  CL115 HEK-293T C77(0.73)  LDD0983  [4]
 LDCM0386  CL116 HEK-293T C77(0.74)  LDD0984  [4]
 LDCM0387  CL117 HEK-293T C77(0.95)  LDD0985  [4]
 LDCM0388  CL118 HEK-293T C77(0.81)  LDD0986  [4]
 LDCM0389  CL119 HEK-293T C77(0.71)  LDD0987  [4]
 LDCM0390  CL12 HEK-293T C77(0.57)  LDD0988  [4]
 LDCM0391  CL120 HEK-293T C77(0.82)  LDD0989  [4]
 LDCM0392  CL121 HEK-293T C77(0.56)  LDD0990  [4]
 LDCM0393  CL122 HEK-293T C77(0.62)  LDD0991  [4]
 LDCM0394  CL123 HEK-293T C77(0.74)  LDD0992  [4]
 LDCM0395  CL124 HEK-293T C77(0.64)  LDD0993  [4]
 LDCM0396  CL125 HEK-293T C77(1.14)  LDD0994  [4]
 LDCM0397  CL126 HEK-293T C77(1.10)  LDD0995  [4]
 LDCM0398  CL127 HEK-293T C77(1.18)  LDD0996  [4]
 LDCM0399  CL128 HEK-293T C77(1.52)  LDD0997  [4]
 LDCM0400  CL13 HEK-293T C77(0.49)  LDD0998  [4]
 LDCM0401  CL14 HEK-293T C77(0.43)  LDD0999  [4]
 LDCM0402  CL15 HEK-293T C77(0.40)  LDD1000  [4]
 LDCM0403  CL16 PaTu 8988t C77(1.08)  LDD1282  [4]
 LDCM0404  CL17 PaTu 8988t C77(1.07)  LDD1283  [4]
 LDCM0405  CL18 PaTu 8988t C77(1.16)  LDD1284  [4]
 LDCM0406  CL19 PaTu 8988t C77(1.20)  LDD1285  [4]
 LDCM0407  CL2 HEK-293T C77(0.72)  LDD1005  [4]
 LDCM0408  CL20 PaTu 8988t C77(1.29)  LDD1287  [4]
 LDCM0409  CL21 PaTu 8988t C77(1.55)  LDD1288  [4]
 LDCM0410  CL22 PaTu 8988t C77(1.41)  LDD1289  [4]
 LDCM0411  CL23 PaTu 8988t C77(1.41)  LDD1290  [4]
 LDCM0412  CL24 PaTu 8988t C77(1.27)  LDD1291  [4]
 LDCM0413  CL25 PaTu 8988t C77(1.07)  LDD1292  [4]
 LDCM0414  CL26 PaTu 8988t C77(1.28)  LDD1293  [4]
 LDCM0415  CL27 PaTu 8988t C77(1.41)  LDD1294  [4]
 LDCM0416  CL28 PaTu 8988t C77(1.52)  LDD1295  [4]
 LDCM0417  CL29 PaTu 8988t C77(1.38)  LDD1296  [4]
 LDCM0418  CL3 HEK-293T C77(0.76)  LDD1016  [4]
 LDCM0419  CL30 PaTu 8988t C77(1.36)  LDD1298  [4]
 LDCM0420  CL31 HEK-293T C77(0.81)  LDD1018  [4]
 LDCM0421  CL32 HEK-293T C77(0.62)  LDD1019  [4]
 LDCM0422  CL33 HEK-293T C77(0.63)  LDD1020  [4]
 LDCM0423  CL34 HEK-293T C77(0.81)  LDD1021  [4]
 LDCM0424  CL35 HEK-293T C77(0.64)  LDD1022  [4]
 LDCM0425  CL36 HEK-293T C77(0.65)  LDD1023  [4]
 LDCM0426  CL37 HEK-293T C77(0.58)  LDD1024  [4]
 LDCM0428  CL39 HEK-293T C77(0.38)  LDD1026  [4]
 LDCM0429  CL4 HEK-293T C77(0.51)  LDD1027  [4]
 LDCM0430  CL40 HEK-293T C77(0.54)  LDD1028  [4]
 LDCM0431  CL41 HEK-293T C77(0.54)  LDD1029  [4]
 LDCM0432  CL42 HEK-293T C77(0.41)  LDD1030  [4]
 LDCM0433  CL43 HEK-293T C77(0.38)  LDD1031  [4]
 LDCM0434  CL44 HEK-293T C77(0.57)  LDD1032  [4]
 LDCM0435  CL45 HEK-293T C77(0.41)  LDD1033  [4]
 LDCM0436  CL46 HEK-293T C77(0.88)  LDD1034  [4]
 LDCM0437  CL47 HEK-293T C77(0.88)  LDD1035  [4]
 LDCM0438  CL48 HEK-293T C77(0.73)  LDD1036  [4]
 LDCM0439  CL49 HEK-293T C77(0.92)  LDD1037  [4]
 LDCM0440  CL5 HEK-293T C77(0.47)  LDD1038  [4]
 LDCM0441  CL50 HEK-293T C77(0.74)  LDD1039  [4]
 LDCM0442  CL51 HEK-293T C77(0.92)  LDD1040  [4]
 LDCM0443  CL52 HEK-293T C77(1.52)  LDD1041  [4]
 LDCM0444  CL53 HEK-293T C77(1.60)  LDD1042  [4]
 LDCM0445  CL54 HEK-293T C77(0.66)  LDD1043  [4]
 LDCM0446  CL55 HEK-293T C77(0.76)  LDD1044  [4]
 LDCM0447  CL56 HEK-293T C77(1.02)  LDD1045  [4]
 LDCM0448  CL57 HEK-293T C77(1.13)  LDD1046  [4]
 LDCM0449  CL58 HEK-293T C77(1.01)  LDD1047  [4]
 LDCM0450  CL59 HEK-293T C77(0.82)  LDD1048  [4]
 LDCM0451  CL6 HEK-293T C77(0.58)  LDD1049  [4]
 LDCM0452  CL60 HEK-293T C77(0.60)  LDD1050  [4]
 LDCM0453  CL61 HEK-293T C77(10.50)  LDD1051  [4]
 LDCM0454  CL62 HEK-293T C77(1.71)  LDD1052  [4]
 LDCM0455  CL63 HEK-293T C77(0.86)  LDD1053  [4]
 LDCM0456  CL64 HEK-293T C77(1.39)  LDD1054  [4]
 LDCM0457  CL65 HEK-293T C77(0.89)  LDD1055  [4]
 LDCM0458  CL66 HEK-293T C77(0.97)  LDD1056  [4]
 LDCM0459  CL67 HEK-293T C77(1.11)  LDD1057  [4]
 LDCM0460  CL68 HEK-293T C77(0.92)  LDD1058  [4]
 LDCM0461  CL69 HEK-293T C77(1.22)  LDD1059  [4]
 LDCM0462  CL7 HEK-293T C77(0.37)  LDD1060  [4]
 LDCM0463  CL70 HEK-293T C77(1.56)  LDD1061  [4]
 LDCM0464  CL71 HEK-293T C77(1.00)  LDD1062  [4]
 LDCM0465  CL72 HEK-293T C77(0.91)  LDD1063  [4]
 LDCM0466  CL73 HEK-293T C77(1.20)  LDD1064  [4]
 LDCM0467  CL74 HEK-293T C77(1.24)  LDD1065  [4]
 LDCM0469  CL76 HEK-293T C77(0.83)  LDD1067  [4]
 LDCM0470  CL77 HEK-293T C77(1.38)  LDD1068  [4]
 LDCM0471  CL78 HEK-293T C77(0.81)  LDD1069  [4]
 LDCM0472  CL79 HEK-293T C77(1.09)  LDD1070  [4]
 LDCM0473  CL8 HEK-293T C77(1.14)  LDD1071  [4]
 LDCM0474  CL80 HEK-293T C77(0.94)  LDD1072  [4]
 LDCM0475  CL81 HEK-293T C77(1.41)  LDD1073  [4]
 LDCM0476  CL82 HEK-293T C77(2.28)  LDD1074  [4]
 LDCM0477  CL83 HEK-293T C77(1.66)  LDD1075  [4]
 LDCM0478  CL84 HEK-293T C77(0.78)  LDD1076  [4]
 LDCM0479  CL85 HEK-293T C77(0.95)  LDD1077  [4]
 LDCM0480  CL86 HEK-293T C77(0.85)  LDD1078  [4]
 LDCM0481  CL87 HEK-293T C77(1.06)  LDD1079  [4]
 LDCM0482  CL88 HEK-293T C77(1.18)  LDD1080  [4]
 LDCM0483  CL89 HEK-293T C77(0.93)  LDD1081  [4]
 LDCM0484  CL9 HEK-293T C77(1.18)  LDD1082  [4]
 LDCM0485  CL90 HEK-293T C77(1.19)  LDD1083  [4]
 LDCM0486  CL91 HEK-293T C77(1.21)  LDD1084  [4]
 LDCM0487  CL92 HEK-293T C77(0.83)  LDD1085  [4]
 LDCM0488  CL93 HEK-293T C77(0.88)  LDD1086  [4]
 LDCM0489  CL94 HEK-293T C77(0.49)  LDD1087  [4]
 LDCM0490  CL95 HEK-293T C77(0.48)  LDD1088  [4]
 LDCM0491  CL96 HEK-293T C77(0.64)  LDD1089  [4]
 LDCM0492  CL97 HEK-293T C77(0.70)  LDD1090  [4]
 LDCM0493  CL98 HEK-293T C77(0.67)  LDD1091  [4]
 LDCM0494  CL99 HEK-293T C77(0.79)  LDD1092  [4]
 LDCM0495  E2913 HEK-293T C77(0.95)  LDD1698  [8]
 LDCM0468  Fragment33 HEK-293T C77(0.91)  LDD1066  [4]
 LDCM0427  Fragment51 HEK-293T C77(0.49)  LDD1025  [4]
 LDCM0179  JZ128 PC-3 N.A.  LDD0462  [2]
 LDCM0022  KB02 HCT 116 C77(1.42)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C77(1.35)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C77(1.71)  LDD0082  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C77(0.84)  LDD2125  [3]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C77(1.06)  LDD2137  [3]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C77(1.13)  LDD2141  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytochrome b5 type B (CYB5B) Cytochrome b5 family O43169
Cytochrome P450 4F2 (CYP4F2) Cytochrome P450 family P78329
Palmitoyltransferase ZDHHC21 (ZDHHC21) DHHC palmitoyltransferase family Q8IVQ6
NADH-cytochrome b5 reductase 3 (CYB5R3) Flavoprotein pyridine nucleotide cytochrome reductase family P00387
Beta-hexosaminidase subunit beta (HEXB) Glycosyl hydrolase 20 family P07686
Heme oxygenase 1 (HMOX1) Heme oxygenase family P09601
Heme oxygenase 2 (HMOX2) Heme oxygenase family P30519
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (PLPP6) PA-phosphatase related phosphoesterase family Q8IY26
GTPase IMAP family member 5 (GIMAP5) AIG1/Toc34/Toc159-like paraseptin GTPase family Q96F15
Ubiquitin-conjugating enzyme E2 J1 (UBE2J1) Ubiquitin-conjugating enzyme family Q9Y385
V-type proton ATPase 16 kDa proteolipid subunit c (ATP6V0C) V-ATPase proteolipid subunit family P27449
V-type proton ATPase 21 kDa proteolipid subunit c'' (ATP6V0B) V-ATPase proteolipid subunit family Q99437
Vitamin K epoxide reductase complex subunit 1 (VKORC1) VKOR family Q9BQB6
Transporter and channel
Click To Hide/Show 16 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proton-coupled zinc antiporter SLC30A8 (SLC30A8) Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family Q8IWU4
Interferon-induced transmembrane protein 3 (IFITM3) CD225/Dispanin family Q01628
Protein cornichon homolog 3 (CNIH3) Cornichon family Q8TBE1
Monocarboxylate transporter 13 (SLC16A13) Monocarboxylate porter (TC 2.A.1.13) family Q7RTY0
Membrane-spanning 4-domains subfamily A member 13 (MS4A13) MS4A family Q5J8X5
Nucleotide sugar transporter SLC35B4 (SLC35B4) Nucleotide-sugar transporter family Q969S0
Proton channel OTOP3 (OTOP3) Otopetrin family Q7RTS5
Transferrin receptor protein 1 (TFRC) Peptidase M28 family P02786
Small integral membrane protein 1 (SMIM1) SMIM1 family B2RUZ4
Vesicle-associated membrane protein 3 (VAMP3) Synaptobrevin family Q15836
Syntaxin-6 (STX6) Syntaxin family O43752
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) Tim17/Tim22/Tim23 family O14925
Solute carrier family 35 member G1 (SLC35G1) TMEM20 family Q2M3R5
Proteolipid protein 2 (PLP2) . Q04941
Synaptojanin-2-binding protein (SYNJ2BP) . P57105
Transmembrane protein 187 (TMEM187) . Q14656
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Lysophosphatidic acid receptor 3 (LPAR3) G-protein coupled receptor 1 family Q9UBY5
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CMRF35-like molecule 6 (CD300C) CD300 family Q08708
Other
Click To Hide/Show 25 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Bcl-2-like protein 13 (BCL2L13) Bcl-2 family Q9BXK5
BET1 homolog (BET1) BET1 family O15155
Mitochondrial fission 1 protein (FIS1) FIS1 family Q9Y3D6
Ninjurin-2 (NINJ2) Ninjurin family Q9NZG7
ORM1-like protein 2 (ORMDL2) ORM family Q53FV1
Claudin domain-containing protein 2 (CLDND2) PMP-22/EMP/MP20 family Q8NHS1
Epithelial membrane protein 3 (EMP3) PMP-22/EMP/MP20 family P54852
Protein NKG7 (NKG7) PMP-22/EMP/MP20 family Q16617
Stress-associated endoplasmic reticulum protein 1 (SERP1) RAMP4 family Q9Y6X1
Stress-associated endoplasmic reticulum protein 2 (SERP2) RAMP4 family Q8N6R1
Protein reprimo (RPRM) Reprimo family Q9NS64
Single-pass membrane and coiled-coil domain-containing protein 4 (SMCO4) SMCO4 family Q9NRQ5
Vesicle-associated membrane protein 4 (VAMP4) Synaptobrevin family O75379
Syntaxin-7 (STX7) Syntaxin family O15400
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) Tim17/Tim22/Tim23 family Q9NPL8
Transmembrane protein 11, mitochondrial (TMEM11) TMEM11 family P17152
Transmembrane protein 19 (TMEM19) TMEM19 family Q96HH6
Receptor-transporting protein 2 (RTP2) TMEM7 family Q5QGT7
Serotransferrin (TF) Transferrin family P02787
Protein YIF1A (YIF1A) YIF1 family O95070
Immediate early response 3-interacting protein 1 (IER3IP1) YOS1 family Q9Y5U9
Coiled-coil domain-containing protein 167 (CCDC167) . Q9P0B6
Transmembrane protein 107 (TMEM107) . Q6UX40
Transmembrane protein 140 (TMEM140) . Q9NV12
Uncharacterized protein C5orf46 (C5orf46) . Q6UWT4

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402