Details of the Target

General Information of Target

Target ID LDTP01510
Target Name Zinc finger protein-like 1 (ZFPL1)
Gene Name ZFPL1
Gene ID 7542
Synonyms
Zinc finger protein-like 1; Zinc finger protein MCG4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGLCKCPKRKVTNLFCFEHRVNVCEHCLVANHAKCIVQSYLQWLQDSDYNPNCRLCNIPL
ASRETTRLVCYDLFHWACLNERAAQLPRNTAPAGYQCPSCNGPIFPPTNLAGPVASALRE
KLATVNWARAGLGLPLIDEVVSPEPEPLNTSDFSDWSSFNASSTPGPEEVDSASAAPAFY
SQAPRPPASPGRPEQHTVIHMGNPEPLTHAPRKVYDTRDDDRTPGLHGDCDDDKYRRRPA
LGWLARLLRSRAGSRKRPLTLLQRAGLLLLLGLLGFLALLALMSRLGRAAADSDPNLDPL
MNPHIRVGPS
Target Bioclass
Other
Family
ZFPL1 family
Subcellular location
Golgi apparatus, cis-Golgi network membrane
Function Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.
Uniprot ID
O95159
Ensemble ID
ENST00000294258.8
HGNC ID
HGNC:12868

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 24 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		14.38  LDD0402  [1]
TH211
 Probe Info  		Y235(17.26)  LDD0260  [2]
ONAyne
 Probe Info  		K234(1.06)  LDD0274  [3]
STPyne
 Probe Info  		K10(8.70); K121(2.01); K213(0.69); K234(7.50)  LDD0277  [3]
JZ128-DTB
 Probe Info  		N.A.  LDD0462  [4]
THZ1-DTB
 Probe Info  		C230(0.96)  LDD0460  [4]
BTD
 Probe Info  		C16(1.21)  LDD2099  [5]
AHL-Pu-1
 Probe Info  		C230(2.59)  LDD0171  [6]
DBIA
 Probe Info  		C56(0.96); C24(0.91); C27(0.91)  LDD0078  [7]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [8]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [8]
Lodoacetamide azide
 Probe Info  		C16(0.00); C56(0.00)  LDD0037  [8]
IPM
 Probe Info  		N.A.  LDD0025  [9]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [9]
NAIA_4
 Probe Info  		N.A.  LDD2226  [10]
WYneN
 Probe Info  		N.A.  LDD0021  [11]
TFBX
 Probe Info  		N.A.  LDD0148  [9]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [12]
Acrolein
 Probe Info  		N.A.  LDD0217  [13]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [13]
Methacrolein
 Probe Info  		N.A.  LDD0218  [13]
W1
 Probe Info  		C56(0.00); C230(0.00)  LDD0236  [14]
AOyne
 Probe Info  		15.00  LDD0443  [15]
NAIA_5
 Probe Info  		C230(0.00); C16(0.00); C56(0.00)  LDD2223  [10]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C106
 Probe Info  		18.25  LDD1793  [16]
C107
 Probe Info  		5.78  LDD1794  [16]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C230(0.82)  LDD2112  [5]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C16(0.86)  LDD2117  [5]
 LDCM0026  4SU-RNA+native RNA DM93 C230(2.59)  LDD0171  [6]
 LDCM0214  AC1 HCT 116 C16(0.81); C24(1.14); C27(1.14); C35(0.52)  LDD0531  [7]
 LDCM0215  AC10 HCT 116 C16(0.79); C56(0.91)  LDD0532  [7]
 LDCM0216  AC100 HCT 116 C16(0.78); C230(1.07); C24(0.99); C27(0.99)  LDD0533  [7]
 LDCM0217  AC101 HCT 116 C16(0.68); C230(1.17); C24(0.87); C27(0.87)  LDD0534  [7]
 LDCM0218  AC102 HCT 116 C16(0.77); C230(0.98); C24(0.83); C27(0.83)  LDD0535  [7]
 LDCM0219  AC103 HCT 116 C16(0.67); C230(1.23); C24(0.84); C27(0.84)  LDD0536  [7]
 LDCM0220  AC104 HCT 116 C16(0.72); C230(1.02); C24(0.81); C27(0.81)  LDD0537  [7]
 LDCM0221  AC105 HCT 116 C16(0.75); C230(1.30); C24(0.80); C27(0.80)  LDD0538  [7]
 LDCM0222  AC106 HCT 116 C16(0.74); C230(1.31); C24(0.82); C27(0.82)  LDD0539  [7]
 LDCM0223  AC107 HCT 116 C16(0.63); C230(1.18); C24(0.85); C27(0.85)  LDD0540  [7]
 LDCM0224  AC108 HCT 116 C16(0.87); C230(1.12); C24(0.96); C27(0.96)  LDD0541  [7]
 LDCM0225  AC109 HCT 116 C16(0.84); C230(1.20); C24(0.86); C27(0.86)  LDD0542  [7]
 LDCM0226  AC11 HCT 116 C16(0.80); C56(1.04)  LDD0543  [7]
 LDCM0227  AC110 HCT 116 C16(0.71); C230(1.07); C24(0.92); C27(0.92)  LDD0544  [7]
 LDCM0228  AC111 HCT 116 C16(0.73); C230(0.94); C24(0.92); C27(0.92)  LDD0545  [7]
 LDCM0229  AC112 HCT 116 C16(0.71); C230(1.09); C24(0.87); C27(0.87)  LDD0546  [7]
 LDCM0230  AC113 HCT 116 C16(0.99); C230(1.03); C24(1.02); C27(1.02)  LDD0547  [7]
 LDCM0231  AC114 HCT 116 C16(0.97); C230(1.45); C24(0.97); C27(0.98)  LDD0548  [7]
 LDCM0232  AC115 HCT 116 C16(0.87); C230(1.72); C24(0.89); C27(0.89)  LDD0549  [7]
 LDCM0233  AC116 HCT 116 C16(1.01); C230(1.56); C24(0.94); C27(0.93)  LDD0550  [7]
 LDCM0234  AC117 HCT 116 C16(1.01); C230(1.33); C24(0.98); C27(0.97)  LDD0551  [7]
 LDCM0235  AC118 HCT 116 C16(1.00); C230(1.42); C24(1.00); C27(1.01)  LDD0552  [7]
 LDCM0236  AC119 HCT 116 C16(1.09); C230(1.51); C24(0.89); C27(0.87)  LDD0553  [7]
 LDCM0237  AC12 HCT 116 C16(0.88); C56(1.00)  LDD0554  [7]
 LDCM0238  AC120 HCT 116 C16(1.12); C230(0.93); C24(1.02); C27(1.00)  LDD0555  [7]
 LDCM0239  AC121 HCT 116 C16(0.93); C230(1.27); C24(1.00); C27(0.99)  LDD0556  [7]
 LDCM0240  AC122 HCT 116 C16(1.02); C230(1.48); C24(0.88); C27(0.90)  LDD0557  [7]
 LDCM0241  AC123 HCT 116 C16(0.94); C230(1.22); C24(0.95); C27(0.96)  LDD0558  [7]
 LDCM0242  AC124 HCT 116 C16(1.05); C230(1.15); C24(1.03); C27(1.03)  LDD0559  [7]
 LDCM0243  AC125 HCT 116 C16(1.21); C230(1.56); C24(0.88); C27(0.91)  LDD0560  [7]
 LDCM0244  AC126 HCT 116 C16(0.96); C230(1.48); C24(0.93); C27(0.96)  LDD0561  [7]
 LDCM0245  AC127 HCT 116 C16(0.93); C230(1.71); C24(0.91); C27(0.92)  LDD0562  [7]
 LDCM0246  AC128 HCT 116 C16(1.17); C230(1.43); C24(0.95); C27(0.95)  LDD0563  [7]
 LDCM0247  AC129 HCT 116 C16(0.90); C230(0.82); C24(1.12); C27(1.12)  LDD0564  [7]
 LDCM0249  AC130 HCT 116 C16(1.01); C230(1.27); C24(0.87); C27(0.87)  LDD0566  [7]
 LDCM0250  AC131 HCT 116 C16(0.96); C230(0.93); C24(1.19); C27(1.19)  LDD0567  [7]
 LDCM0251  AC132 HCT 116 C16(0.95); C230(1.18); C24(1.04); C27(1.04)  LDD0568  [7]
 LDCM0252  AC133 HCT 116 C16(0.94); C230(1.37); C24(1.03); C27(1.03)  LDD0569  [7]
 LDCM0253  AC134 HCT 116 C16(0.98); C230(1.32); C24(0.98); C27(0.98)  LDD0570  [7]
 LDCM0254  AC135 HCT 116 C16(1.06); C230(1.41); C24(1.04); C27(1.04)  LDD0571  [7]
 LDCM0255  AC136 HCT 116 C16(0.90); C230(1.16); C24(1.02); C27(1.02)  LDD0572  [7]
 LDCM0256  AC137 HCT 116 C16(0.94); C230(1.02); C24(1.19); C27(1.19)  LDD0573  [7]
 LDCM0257  AC138 HCT 116 C16(0.94); C230(1.42); C24(1.14); C27(1.14)  LDD0574  [7]
 LDCM0258  AC139 HCT 116 C16(0.95); C230(1.23); C24(1.11); C27(1.11)  LDD0575  [7]
 LDCM0259  AC14 HCT 116 C16(0.92); C56(1.16)  LDD0576  [7]
 LDCM0260  AC140 HCT 116 C16(1.04); C230(1.31); C24(1.01); C27(1.01)  LDD0577  [7]
 LDCM0261  AC141 HCT 116 C16(1.00); C230(1.22); C24(1.04); C27(1.04)  LDD0578  [7]
 LDCM0262  AC142 HCT 116 C16(0.93); C230(1.07); C24(1.11); C27(1.11)  LDD0579  [7]
 LDCM0263  AC143 HCT 116 C56(0.90); C24(0.98); C27(0.98); C16(0.99)  LDD0580  [7]
 LDCM0264  AC144 HCT 116 C16(0.76); C24(0.89); C27(0.94); C56(1.08)  LDD0581  [7]
 LDCM0265  AC145 HCT 116 C16(0.74); C24(0.96); C27(1.15); C56(1.23)  LDD0582  [7]
 LDCM0266  AC146 HCT 116 C16(0.67); C24(0.82); C27(1.03); C56(1.09)  LDD0583  [7]
 LDCM0267  AC147 HCT 116 C27(0.85); C24(0.89); C16(0.93); C56(1.25)  LDD0584  [7]
 LDCM0268  AC148 HCT 116 C16(0.61); C24(0.85); C56(0.98); C27(1.00)  LDD0585  [7]
 LDCM0269  AC149 HCT 116 C16(0.64); C24(0.82); C56(0.92); C27(1.07)  LDD0586  [7]
 LDCM0270  AC15 HCT 116 C16(0.96); C56(1.19)  LDD0587  [7]
 LDCM0271  AC150 HCT 116 C16(0.82); C56(0.89); C24(1.08); C27(1.09)  LDD0588  [7]
 LDCM0272  AC151 HCT 116 C16(0.91); C24(0.92); C27(1.09); C230(1.33)  LDD0589  [7]
 LDCM0273  AC152 HCT 116 C16(0.72); C24(0.97); C27(1.20); C56(1.21)  LDD0590  [7]
 LDCM0274  AC153 HCT 116 C16(0.48); C24(0.88); C56(1.10); C27(1.22)  LDD0591  [7]
 LDCM0621  AC154 HCT 116 C16(0.72); C230(1.56); C24(1.34); C27(1.09)  LDD2158  [7]
 LDCM0622  AC155 HCT 116 C16(0.69); C230(1.23); C24(0.98); C27(1.09)  LDD2159  [7]
 LDCM0623  AC156 HCT 116 C16(0.76); C230(1.16); C24(1.18); C27(1.22)  LDD2160  [7]
 LDCM0624  AC157 HCT 116 C16(0.85); C230(1.10); C24(1.30); C27(1.25)  LDD2161  [7]
 LDCM0276  AC17 HCT 116 C24(0.86); C27(0.86); C56(0.95); C16(1.04)  LDD0593  [7]
 LDCM0277  AC18 HCT 116 C16(0.97); C56(1.08); C24(1.13); C27(1.13)  LDD0594  [7]
 LDCM0278  AC19 HCT 116 C24(0.93); C27(0.93); C16(1.01); C230(1.36)  LDD0595  [7]
 LDCM0279  AC2 HCT 116 C35(0.85); C53(0.85); C16(0.89); C56(0.97)  LDD0596  [7]
 LDCM0280  AC20 HCT 116 C24(1.01); C27(1.01); C16(1.09); C230(1.22)  LDD0597  [7]
 LDCM0281  AC21 HCT 116 C16(0.93); C24(0.96); C27(0.96); C56(0.97)  LDD0598  [7]
 LDCM0282  AC22 HCT 116 C230(0.92); C24(0.94); C27(0.94); C56(0.96)  LDD0599  [7]
 LDCM0283  AC23 HCT 116 C24(0.85); C27(0.85); C230(0.94); C16(0.97)  LDD0600  [7]
 LDCM0284  AC24 HCT 116 C24(0.88); C27(0.88); C56(1.03); C230(1.05)  LDD0601  [7]
 LDCM0285  AC25 HCT 116 C56(0.94); C35(0.94); C53(0.94); C24(1.08)  LDD0602  [7]
 LDCM0286  AC26 HCT 116 C35(0.57); C53(0.57); C16(0.72); C56(0.73)  LDD0603  [7]
 LDCM0287  AC27 HCT 116 C35(0.67); C53(0.67); C16(0.73); C24(0.93)  LDD0604  [7]
 LDCM0288  AC28 HCT 116 C56(0.71); C16(0.78); C24(0.83); C27(0.83)  LDD0605  [7]
 LDCM0289  AC29 HCT 116 C16(0.62); C35(0.72); C53(0.72); C24(0.88)  LDD0606  [7]
 LDCM0290  AC3 HCT 116 C35(0.75); C53(0.75); C56(0.76); C16(0.84)  LDD0607  [7]
 LDCM0291  AC30 HCT 116 C16(0.62); C35(0.74); C53(0.74); C56(0.78)  LDD0608  [7]
 LDCM0292  AC31 HCT 116 C16(0.53); C35(0.67); C53(0.67); C24(0.81)  LDD0609  [7]
 LDCM0293  AC32 HCT 116 C16(0.61); C35(0.71); C53(0.71); C24(0.87)  LDD0610  [7]
 LDCM0294  AC33 HCT 116 C16(0.57); C35(0.67); C53(0.67); C24(0.88)  LDD0611  [7]
 LDCM0295  AC34 HCT 116 C56(0.63); C16(0.64); C35(0.88); C53(0.88)  LDD0612  [7]
 LDCM0296  AC35 HCT 116 C230(0.76); C16(0.91); C35(1.02); C53(1.02)  LDD0613  [7]
 LDCM0297  AC36 HCT 116 C230(0.83); C16(1.02); C24(1.16); C27(1.16)  LDD0614  [7]
 LDCM0298  AC37 HCT 116 C230(0.84); C35(0.89); C53(0.89); C16(0.99)  LDD0615  [7]
 LDCM0299  AC38 HCT 116 C16(0.89); C35(0.97); C53(0.97); C230(1.00)  LDD0616  [7]
 LDCM0300  AC39 HCT 116 C16(0.83); C35(0.93); C53(0.93); C230(1.05)  LDD0617  [7]
 LDCM0301  AC4 HCT 116 C35(0.52); C53(0.52); C16(0.76); C56(1.01)  LDD0618  [7]
 LDCM0302  AC40 HCT 116 C35(0.88); C53(0.88); C16(0.94); C24(1.04)  LDD0619  [7]
 LDCM0303  AC41 HCT 116 C230(0.90); C35(0.91); C53(0.91); C16(0.93)  LDD0620  [7]
 LDCM0304  AC42 HCT 116 C16(0.85); C230(0.99); C56(1.12); C24(1.13)  LDD0621  [7]
 LDCM0305  AC43 HCT 116 C35(0.87); C53(0.87); C16(0.89); C24(1.04)  LDD0622  [7]
 LDCM0306  AC44 HCT 116 C16(0.95); C35(0.96); C53(0.96); C230(0.99)  LDD0623  [7]
 LDCM0307  AC45 HCT 116 C35(0.75); C53(0.75); C16(0.80); C24(1.01)  LDD0624  [7]
 LDCM0308  AC46 HCT 116 C35(0.86); C53(0.86); C230(0.93); C78(0.94)  LDD0625  [7]
 LDCM0309  AC47 HCT 116 C16(0.91); C230(0.93); C24(1.01); C27(1.01)  LDD0626  [7]
 LDCM0310  AC48 HCT 116 C78(0.67); C35(0.70); C53(0.70); C24(0.77)  LDD0627  [7]
 LDCM0311  AC49 HCT 116 C35(0.72); C53(0.72); C78(0.90); C24(0.90)  LDD0628  [7]
 LDCM0312  AC5 HCT 116 C35(0.56); C53(0.56); C16(0.83); C56(0.91)  LDD0629  [7]
 LDCM0313  AC50 HCT 116 C35(0.67); C53(0.67); C24(0.96); C27(0.96)  LDD0630  [7]
 LDCM0314  AC51 HCT 116 C230(0.84); C78(0.89); C16(1.08); C24(1.20)  LDD0631  [7]
 LDCM0315  AC52 HCT 116 C78(0.84); C230(1.04); C16(1.05); C24(1.07)  LDD0632  [7]
 LDCM0316  AC53 HCT 116 C35(0.84); C53(0.84); C16(0.92); C78(1.00)  LDD0633  [7]
 LDCM0317  AC54 HCT 116 C35(0.97); C53(0.97); C24(0.98); C27(0.98)  LDD0634  [7]
 LDCM0318  AC55 HCT 116 C16(0.86); C35(0.90); C53(0.90); C24(0.97)  LDD0635  [7]
 LDCM0319  AC56 HCT 116 C35(0.65); C53(0.65); C78(0.87); C24(0.89)  LDD0636  [7]
 LDCM0320  AC57 HCT 116 C56(0.75); C16(0.83); C24(0.94); C27(0.94)  LDD0637  [7]
 LDCM0321  AC58 HCT 116 C56(0.75); C16(0.92); C78(1.08); C230(1.10)  LDD0638  [7]
 LDCM0322  AC59 HCT 116 C56(0.84); C16(0.87); C78(0.96); C24(1.03)  LDD0639  [7]
 LDCM0323  AC6 HCT 116 C56(0.53); C16(0.92)  LDD0640  [7]
 LDCM0324  AC60 HCT 116 C16(0.69); C56(0.81); C24(0.90); C27(0.90)  LDD0641  [7]
 LDCM0325  AC61 HCT 116 C16(0.71); C56(0.78); C78(0.90); C24(0.98)  LDD0642  [7]
 LDCM0326  AC62 HCT 116 C78(0.79); C16(0.80); C24(0.96); C27(0.96)  LDD0643  [7]
 LDCM0327  AC63 HCT 116 C16(0.82); C56(0.83); C78(0.84); C24(1.06)  LDD0644  [7]
 LDCM0328  AC64 HCT 116 C16(0.76); C78(0.78); C24(0.85); C27(0.85)  LDD0645  [7]
 LDCM0329  AC65 HCT 116 C16(0.82); C78(0.83); C24(0.94); C27(0.94)  LDD0646  [7]
 LDCM0330  AC66 HCT 116 C16(0.81); C78(0.87); C56(0.88); C24(1.21)  LDD0647  [7]
 LDCM0331  AC67 HCT 116 C16(0.68); C56(0.78); C78(0.91); C24(1.09)  LDD0648  [7]
 LDCM0332  AC68 HCT 116 C16(0.84); C78(0.84); C24(0.87); C27(0.87)  LDD0649  [7]
 LDCM0333  AC69 HCT 116 C78(0.65); C24(0.85); C27(0.85); C56(0.90)  LDD0650  [7]
 LDCM0334  AC7 HCT 116 C16(0.82); C56(0.84)  LDD0651  [7]
 LDCM0335  AC70 HCT 116 C24(0.66); C27(0.66); C78(0.75); C56(0.87)  LDD0652  [7]
 LDCM0336  AC71 HCT 116 C78(0.75); C16(0.77); C24(0.89); C27(0.89)  LDD0653  [7]
 LDCM0337  AC72 HCT 116 C24(0.86); C27(0.86); C16(0.87); C78(0.88)  LDD0654  [7]
 LDCM0338  AC73 HCT 116 C24(0.68); C27(0.68); C78(0.81); C16(0.86)  LDD0655  [7]
 LDCM0339  AC74 HCT 116 C24(0.77); C27(0.77); C16(0.80); C78(0.81)  LDD0656  [7]
 LDCM0340  AC75 HCT 116 C24(0.66); C27(0.66); C78(0.69); C56(0.81)  LDD0657  [7]
 LDCM0341  AC76 HCT 116 C24(0.82); C27(0.82); C78(0.82); C16(0.86)  LDD0658  [7]
 LDCM0342  AC77 HCT 116 C78(0.81); C16(0.82); C24(0.94); C27(0.94)  LDD0659  [7]
 LDCM0343  AC78 HCT 116 C78(0.64); C24(0.77); C27(0.77); C56(0.79)  LDD0660  [7]
 LDCM0344  AC79 HCT 116 C78(0.82); C16(0.84); C24(0.88); C27(0.88)  LDD0661  [7]
 LDCM0345  AC8 HCT 116 C16(0.88); C56(1.08)  LDD0662  [7]
 LDCM0346  AC80 HCT 116 C16(0.74); C78(0.79); C56(0.80); C24(0.81)  LDD0663  [7]
 LDCM0347  AC81 HCT 116 C78(0.78); C230(0.78); C16(0.81); C56(0.89)  LDD0664  [7]
 LDCM0348  AC82 HCT 116 C24(0.63); C27(0.63); C78(0.68); C16(0.84)  LDD0665  [7]
 LDCM0349  AC83 HCT 116 C24(0.92); C27(0.92); C16(1.04); C56(1.19)  LDD0666  [7]
 LDCM0350  AC84 HCT 116 C24(0.84); C27(0.84); C56(0.92); C16(0.92)  LDD0667  [7]
 LDCM0351  AC85 HCT 116 C16(0.82); C24(0.86); C27(0.86); C230(1.32)  LDD0668  [7]
 LDCM0352  AC86 HCT 116 C16(0.94); C56(0.94); C24(1.07); C27(1.07)  LDD0669  [7]
 LDCM0353  AC87 HCT 116 C16(0.85); C56(1.01); C24(1.05); C27(1.05)  LDD0670  [7]
 LDCM0354  AC88 HCT 116 C16(0.82); C56(0.88); C24(1.12); C27(1.12)  LDD0671  [7]
 LDCM0355  AC89 HCT 116 C56(0.84); C24(1.00); C27(1.00); C16(1.03)  LDD0672  [7]
 LDCM0357  AC90 HCT 116 C16(0.88); C56(1.02); C24(1.17); C27(1.17)  LDD0674  [7]
 LDCM0358  AC91 HCT 116 C24(0.80); C27(0.80); C56(0.91); C230(1.04)  LDD0675  [7]
 LDCM0359  AC92 HCT 116 C24(0.91); C27(0.91); C56(0.99); C16(1.00)  LDD0676  [7]
 LDCM0360  AC93 HCT 116 C56(0.88); C24(0.97); C27(0.97); C230(1.02)  LDD0677  [7]
 LDCM0361  AC94 HCT 116 C56(0.68); C24(0.90); C27(0.90); C230(0.97)  LDD0678  [7]
 LDCM0362  AC95 HCT 116 C56(0.69); C24(0.94); C27(0.94); C16(1.10)  LDD0679  [7]
 LDCM0363  AC96 HCT 116 C56(0.63); C24(0.71); C27(0.71); C230(0.92)  LDD0680  [7]
 LDCM0364  AC97 HCT 116 C24(1.05); C27(1.05); C56(1.09); C16(1.10)  LDD0681  [7]
 LDCM0365  AC98 HCT 116 C24(0.65); C27(0.65); C16(0.67); C56(0.76)  LDD0682  [7]
 LDCM0366  AC99 HCT 116 C16(0.66); C56(0.82); C24(0.82); C27(0.82)  LDD0683  [7]
 LDCM0248  AKOS034007472 HCT 116 C16(0.81); C56(0.97)  LDD0565  [7]
 LDCM0356  AKOS034007680 HCT 116 C16(0.82); C56(0.97)  LDD0673  [7]
 LDCM0275  AKOS034007705 HCT 116 C16(0.91); C56(1.06)  LDD0592  [7]
 LDCM0156  Aniline NCI-H1299 13.29  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C56(0.96); C24(0.91); C27(0.91)  LDD0078  [7]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [13]
 LDCM0632  CL-Sc Hep-G2 C230(1.02); C230(0.81)  LDD2227  [10]
 LDCM0367  CL1 HCT 116 C16(0.90); C24(0.93); C27(0.93); C230(1.03)  LDD0684  [7]
 LDCM0368  CL10 HCT 116 C78(0.72); C53(0.80); C16(0.82); C35(0.93)  LDD0685  [7]
 LDCM0369  CL100 HCT 116 C35(0.47); C53(0.47); C16(0.89); C56(0.95)  LDD0686  [7]
 LDCM0370  CL101 HCT 116 C16(0.91); C56(0.94)  LDD0687  [7]
 LDCM0371  CL102 HCT 116 C56(0.72); C16(0.86)  LDD0688  [7]
 LDCM0372  CL103 HCT 116 C16(1.02); C56(1.13)  LDD0689  [7]
 LDCM0373  CL104 HCT 116 C16(0.84); C56(1.67)  LDD0690  [7]
 LDCM0374  CL105 HCT 116 C16(0.87); C24(1.01); C27(1.01); C56(1.11)  LDD0691  [7]
 LDCM0375  CL106 HCT 116 C16(0.68); C24(0.87); C27(0.87); C56(0.91)  LDD0692  [7]
 LDCM0376  CL107 HCT 116 C16(0.84); C24(0.98); C27(0.98); C56(1.08)  LDD0693  [7]
 LDCM0377  CL108 HCT 116 C16(0.99); C24(0.99); C27(0.99); C56(1.12)  LDD0694  [7]
 LDCM0378  CL109 HCT 116 C16(0.87); C24(0.87); C27(0.87); C56(1.02)  LDD0695  [7]
 LDCM0379  CL11 HCT 116 C16(0.73); C53(0.75); C78(0.76); C35(0.81)  LDD0696  [7]
 LDCM0380  CL110 HCT 116 C16(0.85); C24(0.88); C27(0.88); C56(1.07)  LDD0697  [7]
 LDCM0381  CL111 HCT 116 C24(0.86); C27(0.86); C56(0.86); C16(0.93)  LDD0698  [7]
 LDCM0382  CL112 HCT 116 C16(0.73); C35(0.79); C53(0.79); C24(0.95)  LDD0699  [7]
 LDCM0383  CL113 HCT 116 C16(0.53); C35(0.62); C53(0.62); C56(0.80)  LDD0700  [7]
 LDCM0384  CL114 HCT 116 C16(0.55); C35(0.64); C53(0.64); C24(0.95)  LDD0701  [7]
 LDCM0385  CL115 HCT 116 C16(0.62); C35(0.68); C53(0.68); C24(0.95)  LDD0702  [7]
 LDCM0386  CL116 HCT 116 C16(0.58); C35(0.65); C53(0.65); C24(0.91)  LDD0703  [7]
 LDCM0387  CL117 HCT 116 C35(0.78); C53(0.78); C16(0.86); C56(0.93)  LDD0704  [7]
 LDCM0388  CL118 HCT 116 C16(0.94); C35(0.99); C53(0.99); C56(0.99)  LDD0705  [7]
 LDCM0389  CL119 HCT 116 C16(0.89); C35(0.93); C53(0.93); C24(1.01)  LDD0706  [7]
 LDCM0390  CL12 HCT 116 C16(0.80); C78(0.88); C35(0.94); C24(0.95)  LDD0707  [7]
 LDCM0391  CL120 HCT 116 C35(0.88); C53(0.88); C16(0.96); C230(1.00)  LDD0708  [7]
 LDCM0392  CL121 HCT 116 C16(0.87); C230(1.00); C35(1.38); C53(1.38)  LDD0709  [7]
 LDCM0393  CL122 HCT 116 C78(0.83); C16(0.83); C35(0.90); C53(0.90)  LDD0710  [7]
 LDCM0394  CL123 HCT 116 C16(0.75); C35(1.01); C53(1.01); C24(1.06)  LDD0711  [7]
 LDCM0395  CL124 HCT 116 C78(0.74); C16(0.87); C24(0.89); C27(0.89)  LDD0712  [7]
 LDCM0396  CL125 HCT 116 C56(0.88); C24(0.91); C27(0.91); C78(0.94)  LDD0713  [7]
 LDCM0397  CL126 HCT 116 C78(0.86); C56(0.93); C230(0.93); C16(1.01)  LDD0714  [7]
 LDCM0398  CL127 HCT 116 C78(0.89); C56(0.90); C16(0.92); C24(0.99)  LDD0715  [7]
 LDCM0399  CL128 HCT 116 C78(0.82); C16(0.86); C56(0.88); C24(0.99)  LDD0716  [7]
 LDCM0400  CL13 HCT 116 C78(0.59); C53(0.79); C35(0.85); C16(0.85)  LDD0717  [7]
 LDCM0401  CL14 HCT 116 C35(0.80); C16(0.87); C53(0.87); C78(0.88)  LDD0718  [7]
 LDCM0402  CL15 HCT 116 C78(0.69); C53(0.81); C56(0.87); C16(0.90)  LDD0719  [7]
 LDCM0403  CL16 HCT 116 C16(0.92); C56(0.93); C24(1.17); C27(1.17)  LDD0720  [7]
 LDCM0404  CL17 HCT 116 C16(0.86); C24(0.92); C27(0.92); C56(1.08)  LDD0721  [7]
 LDCM0405  CL18 HCT 116 C16(0.82); C24(0.85); C27(0.85); C56(1.16)  LDD0722  [7]
 LDCM0406  CL19 HCT 116 C56(0.83); C16(0.95); C24(1.11); C27(1.11)  LDD0723  [7]
 LDCM0407  CL2 HCT 116 C35(0.82); C78(0.88); C16(0.99); C24(1.01)  LDD0724  [7]
 LDCM0408  CL20 HCT 116 C16(0.91); C56(1.12); C24(1.20); C27(1.20)  LDD0725  [7]
 LDCM0409  CL21 HCT 116 C16(0.75); C24(0.99); C27(0.99); C56(1.02)  LDD0726  [7]
 LDCM0410  CL22 HCT 116 C16(0.76); C24(0.81); C27(0.81); C56(1.49)  LDD0727  [7]
 LDCM0411  CL23 HCT 116 C16(1.00); C24(1.14); C27(1.14); C56(1.25)  LDD0728  [7]
 LDCM0412  CL24 HCT 116 C16(0.79); C24(1.16); C27(1.16); C56(1.16)  LDD0729  [7]
 LDCM0413  CL25 HCT 116 C16(0.77); C24(0.90); C27(0.90); C56(1.30)  LDD0730  [7]
 LDCM0414  CL26 HCT 116 C16(0.93); C24(1.09); C27(1.09); C56(0.96)  LDD0731  [7]
 LDCM0415  CL27 HCT 116 C16(0.91); C24(0.98); C27(0.98); C56(1.20)  LDD0732  [7]
 LDCM0416  CL28 HCT 116 C16(0.85); C24(1.03); C27(1.03); C56(1.08)  LDD0733  [7]
 LDCM0417  CL29 HCT 116 C16(0.87); C24(1.05); C27(1.05); C56(1.03)  LDD0734  [7]
 LDCM0418  CL3 HCT 116 C16(0.94); C230(1.02); C24(0.92); C27(0.92)  LDD0735  [7]
 LDCM0419  CL30 HCT 116 C16(1.07); C24(1.16); C27(1.16); C56(1.14)  LDD0736  [7]
 LDCM0420  CL31 HCT 116 C16(0.71); C24(1.01); C27(1.01); C56(1.10)  LDD0737  [7]
 LDCM0421  CL32 HCT 116 C16(0.76); C24(0.92); C27(0.92); C56(0.84)  LDD0738  [7]
 LDCM0422  CL33 HCT 116 C16(0.72); C24(0.82); C27(0.82); C56(0.90)  LDD0739  [7]
 LDCM0423  CL34 HCT 116 C16(0.76); C24(0.98); C27(0.98); C56(0.90)  LDD0740  [7]
 LDCM0424  CL35 HCT 116 C16(0.76); C24(0.94); C27(0.94); C56(0.84)  LDD0741  [7]
 LDCM0425  CL36 HCT 116 C16(0.79); C24(0.96); C27(0.96); C56(0.73)  LDD0742  [7]
 LDCM0426  CL37 HCT 116 C16(0.73); C24(0.92); C27(0.92); C56(1.25)  LDD0743  [7]
 LDCM0428  CL39 HCT 116 C16(0.73); C24(0.90); C27(0.90); C56(1.48)  LDD0745  [7]
 LDCM0429  CL4 HCT 116 C16(0.91); C230(0.95); C24(0.90); C27(0.90)  LDD0746  [7]
 LDCM0430  CL40 HCT 116 C16(0.68); C24(0.96); C27(0.96); C56(1.41)  LDD0747  [7]
 LDCM0431  CL41 HCT 116 C16(0.72); C24(1.05); C27(1.05); C56(0.94)  LDD0748  [7]
 LDCM0432  CL42 HCT 116 C16(0.58); C24(0.94); C27(0.94); C56(0.90)  LDD0749  [7]
 LDCM0433  CL43 HCT 116 C16(0.76); C24(0.87); C27(0.87); C56(1.14)  LDD0750  [7]
 LDCM0434  CL44 HCT 116 C16(0.72); C24(0.92); C27(0.92); C56(0.97)  LDD0751  [7]
 LDCM0435  CL45 HCT 116 C16(0.75); C24(0.84); C27(0.84); C56(1.09)  LDD0752  [7]
 LDCM0436  CL46 HCT 116 C16(1.21); C230(1.31); C24(0.92); C27(0.92)  LDD0753  [7]
 LDCM0437  CL47 HCT 116 C16(1.26); C230(0.95); C24(0.89); C27(0.89)  LDD0754  [7]
 LDCM0438  CL48 HCT 116 C16(1.35); C230(1.15); C24(0.95); C27(0.95)  LDD0755  [7]
 LDCM0439  CL49 HCT 116 C16(1.27); C230(1.42); C24(0.86); C27(0.86)  LDD0756  [7]
 LDCM0440  CL5 HCT 116 C16(1.07); C230(1.01); C24(1.05); C27(1.05)  LDD0757  [7]
 LDCM0441  CL50 HCT 116 C16(1.10); C230(1.06); C24(0.87); C27(0.87)  LDD0758  [7]
 LDCM0442  CL51 HCT 116 C16(1.19); C230(1.29); C24(0.92); C27(0.92)  LDD0759  [7]
 LDCM0443  CL52 HCT 116 C16(1.21); C230(1.42); C24(0.89); C27(0.89)  LDD0760  [7]
 LDCM0444  CL53 HCT 116 C16(0.88); C230(0.84); C24(0.87); C27(0.87)  LDD0761  [7]
 LDCM0445  CL54 HCT 116 C16(1.36); C230(1.04); C24(0.84); C27(0.84)  LDD0762  [7]
 LDCM0446  CL55 HCT 116 C16(1.39); C230(1.00); C24(0.85); C27(0.85)  LDD0763  [7]
 LDCM0447  CL56 HCT 116 C16(1.18); C230(0.96); C24(0.96); C27(0.96)  LDD0764  [7]
 LDCM0448  CL57 HCT 116 C16(1.30); C230(0.82); C24(0.93); C27(0.93)  LDD0765  [7]
 LDCM0449  CL58 HCT 116 C16(1.34); C230(1.20); C24(0.99); C27(0.99)  LDD0766  [7]
 LDCM0450  CL59 HCT 116 C16(1.33); C230(0.94); C24(0.94); C27(0.94)  LDD0767  [7]
 LDCM0451  CL6 HCT 116 C16(0.88); C230(1.14); C24(0.92); C27(0.92)  LDD0768  [7]
 LDCM0452  CL60 HCT 116 C16(1.48); C230(1.44); C24(0.89); C27(0.89)  LDD0769  [7]
 LDCM0453  CL61 HCT 116 C16(0.78); C230(1.31); C24(0.87); C27(0.87)  LDD0770  [7]
 LDCM0454  CL62 HCT 116 C16(0.92); C230(1.28); C24(0.93); C27(0.93)  LDD0771  [7]
 LDCM0455  CL63 HCT 116 C16(0.83); C230(0.77); C24(0.89); C27(0.89)  LDD0772  [7]
 LDCM0456  CL64 HCT 116 C16(0.99); C230(1.11); C24(0.92); C27(0.92)  LDD0773  [7]
 LDCM0457  CL65 HCT 116 C16(0.86); C230(0.87); C24(0.90); C27(0.90)  LDD0774  [7]
 LDCM0458  CL66 HCT 116 C16(0.74); C230(1.06); C24(0.87); C27(0.87)  LDD0775  [7]
 LDCM0459  CL67 HCT 116 C16(0.85); C230(0.67); C24(0.95); C27(0.95)  LDD0776  [7]
 LDCM0460  CL68 HCT 116 C16(0.67); C230(0.61); C24(0.87); C27(0.87)  LDD0777  [7]
 LDCM0461  CL69 HCT 116 C16(0.82); C230(0.86); C24(0.75); C27(0.75)  LDD0778  [7]
 LDCM0462  CL7 HCT 116 C16(0.83); C230(1.20); C24(0.94); C27(0.94)  LDD0779  [7]
 LDCM0463  CL70 HCT 116 C16(0.79); C230(0.87); C24(0.84); C27(0.84)  LDD0780  [7]
 LDCM0464  CL71 HCT 116 C16(0.83); C230(0.91); C24(0.99); C27(0.99)  LDD0781  [7]
 LDCM0465  CL72 HCT 116 C16(0.90); C230(0.95); C24(1.05); C27(1.05)  LDD0782  [7]
 LDCM0466  CL73 HCT 116 C16(0.96); C230(0.76); C24(0.85); C27(0.85)  LDD0783  [7]
 LDCM0467  CL74 HCT 116 C16(0.88); C230(0.85); C24(0.89); C27(0.89)  LDD0784  [7]
 LDCM0469  CL76 HCT 116 C16(0.90); C230(0.69); C24(1.07); C27(1.07)  LDD0786  [7]
 LDCM0470  CL77 HCT 116 C16(0.90); C230(0.74); C24(1.02); C27(1.02)  LDD0787  [7]
 LDCM0471  CL78 HCT 116 C16(0.87); C230(0.92); C24(1.05); C27(1.05)  LDD0788  [7]
 LDCM0472  CL79 HCT 116 C16(0.96); C230(0.83); C24(1.03); C27(1.03)  LDD0789  [7]
 LDCM0473  CL8 HCT 116 C16(0.77); C230(1.26); C24(0.89); C27(0.89)  LDD0790  [7]
 LDCM0474  CL80 HCT 116 C16(0.87); C230(0.94); C24(1.00); C27(1.00)  LDD0791  [7]
 LDCM0475  CL81 HCT 116 C16(0.99); C230(1.09); C24(0.93); C27(0.93)  LDD0792  [7]
 LDCM0476  CL82 HCT 116 C16(0.86); C230(0.91); C24(0.99); C27(0.99)  LDD0793  [7]
 LDCM0477  CL83 HCT 116 C16(0.91); C230(0.91); C24(0.77); C27(0.77)  LDD0794  [7]
 LDCM0478  CL84 HCT 116 C16(0.78); C230(0.93); C24(0.86); C27(0.86)  LDD0795  [7]
 LDCM0479  CL85 HCT 116 C16(0.76); C230(0.76); C24(0.98); C27(0.98)  LDD0796  [7]
 LDCM0480  CL86 HCT 116 C16(0.80); C230(0.83); C24(0.86); C27(0.86)  LDD0797  [7]
 LDCM0481  CL87 HCT 116 C16(0.96); C230(0.74); C24(0.91); C27(0.91)  LDD0798  [7]
 LDCM0482  CL88 HCT 116 C16(0.94); C230(0.79); C24(1.01); C27(1.01)  LDD0799  [7]
 LDCM0483  CL89 HCT 116 C16(0.90); C230(0.94); C24(0.97); C27(0.97)  LDD0800  [7]
 LDCM0484  CL9 HCT 116 C16(0.83); C230(1.23); C24(0.87); C27(0.87)  LDD0801  [7]
 LDCM0485  CL90 HCT 116 C16(0.84); C230(0.73); C24(1.06); C27(1.06)  LDD0802  [7]
 LDCM0486  CL91 HCT 116 C16(0.84); C24(1.04); C27(1.04); C35(0.56)  LDD0803  [7]
 LDCM0487  CL92 HCT 116 C16(0.86); C24(0.96); C27(0.96); C35(0.52)  LDD0804  [7]
 LDCM0488  CL93 HCT 116 C16(1.08); C24(1.02); C27(1.02); C35(0.62)  LDD0805  [7]
 LDCM0489  CL94 HCT 116 C16(0.98); C24(1.02); C27(1.02); C35(0.71)  LDD0806  [7]
 LDCM0490  CL95 HCT 116 C16(0.82); C24(1.01); C27(1.01); C35(0.47)  LDD0807  [7]
 LDCM0491  CL96 HCT 116 C16(0.76); C24(1.16); C27(1.16); C35(0.69)  LDD0808  [7]
 LDCM0492  CL97 HCT 116 C16(0.80); C24(1.07); C27(1.07); C35(0.67)  LDD0809  [7]
 LDCM0493  CL98 HCT 116 C16(0.84); C24(1.01); C27(1.01); C35(0.58)  LDD0810  [7]
 LDCM0494  CL99 HCT 116 C16(0.84); C24(0.98); C27(0.98); C35(0.70)  LDD0811  [7]
 LDCM0634  CY-0357 Hep-G2 C230(0.90)  LDD2228  [10]
 LDCM0495  E2913 HEK-293T C230(0.99); C56(0.92); C35(0.98); C70(0.67)  LDD1698  [17]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C56(1.36)  LDD1702  [5]
 LDCM0625  F8 Ramos C230(6.91)  LDD2187  [18]
 LDCM0572  Fragment10 Ramos C230(3.64)  LDD2189  [18]
 LDCM0573  Fragment11 Ramos C230(3.07)  LDD2190  [18]
 LDCM0574  Fragment12 Ramos C230(1.41)  LDD2191  [18]
 LDCM0575  Fragment13 Ramos C230(0.50)  LDD2192  [18]
 LDCM0576  Fragment14 Ramos C230(1.42)  LDD2193  [18]
 LDCM0580  Fragment21 Ramos C230(0.46)  LDD2195  [18]
 LDCM0582  Fragment23 Ramos C230(1.70)  LDD2196  [18]
 LDCM0578  Fragment27 Ramos C230(1.22)  LDD2197  [18]
 LDCM0586  Fragment28 Ramos C230(0.20)  LDD2198  [18]
 LDCM0588  Fragment30 Ramos C230(1.04)  LDD2199  [18]
 LDCM0589  Fragment31 Ramos C230(1.37)  LDD2200  [18]
 LDCM0590  Fragment32 Ramos C230(1.91)  LDD2201  [18]
 LDCM0468  Fragment33 HCT 116 C16(0.77); C230(0.96); C24(1.10); C27(1.10)  LDD0785  [7]
 LDCM0596  Fragment38 Ramos C230(1.82)  LDD2203  [18]
 LDCM0566  Fragment4 Ramos C230(1.00)  LDD2184  [18]
 LDCM0427  Fragment51 HCT 116 C16(0.67); C24(0.92); C27(0.92); C56(0.96)  LDD0744  [7]
 LDCM0610  Fragment52 Ramos C230(1.32)  LDD2204  [18]
 LDCM0614  Fragment56 Ramos C230(0.47)  LDD2205  [18]
 LDCM0569  Fragment7 Ramos C230(1.43)  LDD2186  [18]
 LDCM0571  Fragment9 Ramos C230(1.11)  LDD2188  [18]
 LDCM0179  JZ128 PC-3 N.A.  LDD0462  [4]
 LDCM0022  KB02 HCT 116 C230(1.62)  LDD0080  [7]
 LDCM0023  KB03 HCT 116 C230(1.51)  LDD0081  [7]
 LDCM0024  KB05 HCT 116 C230(1.61)  LDD0082  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C16(1.21)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C230(0.82)  LDD2100  [5]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C230(0.96)  LDD2104  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C16(1.25)  LDD2109  [5]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C230(1.49)  LDD2110  [5]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C230(0.99)  LDD2114  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C16(0.98)  LDD2123  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C16(1.04); C230(0.95)  LDD2125  [5]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C16(1.17); C56(0.69)  LDD2136  [5]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C230(1.25)  LDD2141  [5]
 LDCM0627  NUDT7-COV-1 HEK-293T C230(0.77)  LDD2206  [19]
 LDCM0628  OTUB2-COV-1 HEK-293T C230(0.30)  LDD2207  [19]
 LDCM0021  THZ1 HeLa S3 C230(0.96)  LDD0460  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
rRNA methyltransferase 3, mitochondrial (MRM3) RNA methyltransferase TrmH family Q9HC36
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) EBP family Q15125
Very long chain fatty acid elongase 4 (ELOVL4) ELO family Q9GZR5
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) HIBADH-related family P31937
Glutathione S-transferase 3, mitochondrial (MGST3) MAPEG family O14880
Phosphatidylcholine:ceramide cholinephosphotransferase 2 (SGMS2) Sphingomyelin synthase family Q8NHU3
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) . Q9Y680
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) . Q14318
Plasma membrane ascorbate-dependent reductase CYBRD1 (CYBRD1) . Q53TN4
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (TSTD2) . Q5T7W7
Transporter and channel
Click To Hide/Show 17 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Solute carrier family 7 member 14 (SLC7A14) Cationic amino acid transporter (CAT) (TC 2.A.3.3) family Q8TBB6
Sodium-dependent organic anion transporter (SLC10A6) Bile acid:sodium symporter (BASS) family Q3KNW5
Membrane-associated progesterone receptor component 2 (PGRMC2) Cytochrome b5 family O15173
Transmembrane 4 L6 family member 19 (TM4SF19) L6 tetraspanin family Q96DZ7
Hippocampus abundant transcript-like protein 1 (MFSD14B) Major facilitator superfamily Q5SR56
Lens fiber major intrinsic protein (MIP) MIP/aquaporin (TC 1.A.8) family P30301
Membrane-spanning 4-domains subfamily A member 3 (MS4A3) MS4A family Q96HJ5
Thiamine transporter 2 (SLC19A3) Reduced folate carrier (RFC) transporter (TC 2.A.48) family Q9BZV2
Sodium channel regulatory subunit beta-3 (SCN3B) Sodium channel auxiliary subunit SCN3B family Q9NY72
Synaptotagmin-1 (SYT1) Synaptotagmin family P21579
Syntaxin-1A (STX1A) Syntaxin family Q16623
Syntaxin-4 (STX4) Syntaxin family Q12846
Transmembrane protein 106C (TMEM106C) TMEM106 family Q9BVX2
Transmembrane protein 14B (TMEM14B) TMEM14 family Q9NUH8
Barttin (BSND) . Q8WZ55
T-cell surface glycoprotein CD3 epsilon chain (CD3E) . P07766
Transmembrane protein 139 (TMEM139) . Q8IV31
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) BZIP family Q96BA8
Paired-like homeodomain transcription factor LEUTX (LEUTX) Paired homeobox family A8MZ59
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
G-protein coupled receptor 42 (GPR42) G-protein coupled receptor 1 family O15529
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Poliovirus receptor (PVR) Nectin family P15151
Other
Click To Hide/Show 23 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Small ribosomal subunit protein mS40 (MRPS18B) Bacterial ribosomal protein bS18 family Q9Y676
Complexin-4 (CPLX4) Complexin/synaphin family Q7Z7G2
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) ERGIC family Q9Y282
Protein FAM209A (FAM209A) FAM209 family Q5JX71
RAB6-interacting golgin (GORAB) GORAB family Q5T7V8
Low-density lipoprotein receptor class A domain-containing protein 1 (LDLRAD1) LDLR family Q5T700
Transcription termination factor 3, mitochondrial (MTERF3) MTERF family Q96E29
RELT-like protein 2 (RELL2) RELT family Q8NC24
Protein shisa-like-1 (SHISAL1) Shisa family Q3SXP7
Bcl-2-interacting killer (BIK) . Q13323
C-type lectin domain family 10 member A (CLEC10A) . Q8IUN9
Cell growth regulator with RING finger domain protein 1 (CGRRF1) . Q99675
FERM domain-containing protein 3 (FRMD3) . A2A2Y4
Fetal and adult testis-expressed transcript protein (FATE1) . Q969F0
Fibronectin type III domain-containing protein 9 (FNDC9) . Q8TBE3
Lck-interacting transmembrane adapter 1 (LIME1) . Q9H400
NKG2-A/NKG2-B type II integral membrane protein (KLRC1) . P26715
Pleckstrin homology domain-containing family O member 1 (PLEKHO1) . Q53GL0
Protein KASH5 (KASH5) . Q8N6L0
Serine-rich single-pass membrane protein 1 (SSMEM1) . Q8WWF3
Small integral membrane protein 3 (SMIM3) . Q9BZL3
Synapse-associated protein 1 (SYAP1) . Q96A49
Testis-expressed protein 29 (TEX29) . Q8N6K0

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
7 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
8 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
11 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
12 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
13 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
14 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
15 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
16 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
17 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
18 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
19 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.