Details of the Probe

General Information of Probe

Probe ID
LDPC0354
Probe Name
C107
Synonyms
Z4225928007
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 329.36
Lipid-water partition coefficient (xlogp) 3.9
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C16H22F3N3O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-2-[3-(trifluoromethyl)cyclohexyl]acetamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)CC2CCCC(C2)C(F)(F)F
InChI
InChI=1S/C16H22F3N3O/c1-2-3-7-15(21-22-15)8-9-20-14(23)11-12-5-4-6-13(10-12)16(17,18)19/h1,12-13H,3-11H2,(H,20,23)
InChIKey
WOCLSZJKXKKZDY-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

130 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 7.31  LDD1794 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 41.93  LDD1794 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 6.45  LDD1794 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 7.41  LDD1794 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 5.86  LDD1794 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 9.38  LDD1794 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 7.78  LDD1794 
Acid ceramidase (ASAH1) LDTP05905 17.63  LDD1794 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 5.94  LDD1794 
ADP-dependent glucokinase (ADPGK) LDTP11127 8.00  LDD1794 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 27.86  LDD1794 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 9.78  LDD1794 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 7.62  LDD1794 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 7.41  LDD1794 
Antigen peptide transporter 1 (TAP1) LDTP05408 6.96  LDD1794 
ATP-binding cassette sub-family B member 6 (ABCB6) LDTP12303 6.11  LDD1794 
ATP-binding cassette sub-family D member 1 (ABCD1) LDTP03676 7.11  LDD1794 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 10.20  LDD1794 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 7.62  LDD1794 
Atypical kinase COQ8B, mitochondrial (COQ8B) LDTP10201 6.82  LDD1794 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 6.68  LDD1794 
Beta-galactosidase (GLB1) LDTP02837 18.38  LDD1794 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 17.27  LDD1794 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 10.06  LDD1794 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 7.73  LDD1794 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 8.28  LDD1794 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 6.63  LDD1794 
Ceramide glucosyltransferase (UGCG) LDTP06617 5.86  LDD1794 
Ceramide synthase 1 (CERS1) LDTP03394 8.17  LDD1794 
Ceramide synthase 2 (CERS2) LDTP10329 11.31  LDD1794 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 6.50  LDD1794 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 6.45  LDD1794 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 7.57  LDD1794 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 16.68  LDD1794 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 14.72  LDD1794 
Cytochrome b5 type B (CYB5B) LDTP00697 30.70  LDD1794 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 8.75  LDD1794 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.16  LDD1794 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 13.93  LDD1794 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.45  LDD1794 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 5.70  LDD1794 
Dihydrofolate reductase (DHFR) LDTP01769 5.94  LDD1794 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 6.96  LDD1794 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 5.74  LDD1794 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 9.51  LDD1794 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 6.54  LDD1794 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 9.38  LDD1794 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 5.74  LDD1794 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 7.94  LDD1794 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 10.48  LDD1794 
Ethanolamine kinase 1 (ETNK1) LDTP12197 9.45  LDD1794 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 15.45  LDD1794 
Glutaminyl-peptide cyclotransferase-like protein (QPCTL) LDTP12790 20.97  LDD1794 
Glutathione hydrolase 7 (GGT7) LDTP13367 8.00  LDD1794 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 5.86  LDD1794 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 6.41  LDD1794 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 5.70  LDD1794 
Heme A synthase COX15 (COX15) LDTP07931 6.06  LDD1794 
Heme oxygenase 1 (HMOX1) LDTP02359 6.68  LDD1794 
Heme oxygenase 2 (HMOX2) LDTP03540 17.63  LDD1794 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 5.98  LDD1794 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.73  LDD1794 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 7.67  LDD1794 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 8.82  LDD1794 
Lanosterol synthase (LSS) LDTP04183 6.28  LDD1794 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 8.11  LDD1794 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 30.27  LDD1794 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 7.67  LDD1794 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 5.86  LDD1794 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 28.25  LDD1794 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 6.63  LDD1794 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 13.18  LDD1794 
Lysosomal alpha-glucosidase (GAA) LDTP02486 6.82  LDD1794 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 11.39  LDD1794 
Lysosomal protective protein (CTSA) LDTP02505 9.38  LDD1794 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 15.03  LDD1794 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) LDTP00975 6.15  LDD1794 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 15.03  LDD1794 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 7.26  LDD1794 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 6.32  LDD1794 
Multidrug resistance-associated protein 1 (ABCC1) LDTP03671 7.21  LDD1794 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 5.86  LDD1794 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 14.93  LDD1794 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 19.03  LDD1794 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 9.19  LDD1794 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 8.63  LDD1794 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 17.39  LDD1794 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 17.51  LDD1794 
NADPH--cytochrome P450 reductase (POR) LDTP02848 5.94  LDD1794 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 7.16  LDD1794 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 20.68  LDD1794 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 7.73  LDD1794 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 14.83  LDD1794 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 10.78  LDD1794 
Phospholipase A2 group XV (PLA2G15) LDTP09088 14.22  LDD1794 
Phospholipid-transporting ATPase ABCA3 (ABCA3) LDTP10974 5.50  LDD1794 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 7.41  LDD1794 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 12.21  LDD1794 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 15.78  LDD1794 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 7.67  LDD1794 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 12.47  LDD1794 
Prostaglandin reductase 3 (PTGR3) LDTP15422 5.98  LDD1794 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 25.28  LDD1794 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 6.11  LDD1794 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 6.36  LDD1794 
Protein O-GlcNAcase (OGA) LDTP00988 7.26  LDD1794 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 7.11  LDD1794 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.78  LDD1794 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 10.48  LDD1794 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 8.69  LDD1794 
Ras-related protein Rab-24 (RAB24) LDTP10020 5.74  LDD1794 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 9.85  LDD1794 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 8.17  LDD1794 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 7.89  LDD1794 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 8.82  LDD1794 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 27.10  LDD1794 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 9.78  LDD1794 
Sphingosine kinase 2 (SPHK2) LDTP12490 8.11  LDD1794 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 10.20  LDD1794 
Squalene monooxygenase (SQLE) LDTP06142 5.70  LDD1794 
Squalene synthase (FDFT1) LDTP03842 19.97  LDD1794 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 6.06  LDD1794 
Thimet oligopeptidase (THOP1) LDTP04542 6.54  LDD1794 
TLC domain-containing protein 1 (TLCD1) LDTP10182 31.12  LDD1794 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 13.55  LDD1794 
Ubiquitin carboxyl-terminal hydrolase 24 (USP24) LDTP13720 5.70  LDD1794 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 7.26  LDD1794 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 9.78  LDD1794 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 16.00  LDD1794 
Xaa-Pro aminopeptidase 3 (XPNPEP3) LDTP12420 10.63  LDD1794 
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⏷ Show the Full List of 130 Enzyme
111 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 7.36  LDD1794 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 8.17  LDD1794 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 11.39  LDD1794 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 5.98  LDD1794 
ATP synthase subunit a (MT-ATP6) LDTP01804 16.56  LDD1794 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 22.16  LDD1794 
BOS complex subunit NCLN (NCLN) LDTP10036 8.82  LDD1794 
BRI3-binding protein (BRI3BP) LDTP15648 17.15  LDD1794 
Cell cycle control protein 50A (TMEM30A) LDTP12665 5.50  LDD1794 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 5.66  LDD1794 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.52  LDD1794 
Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) LDTP03064 5.62  LDD1794 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 21.86  LDD1794 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 6.92  LDD1794 
Derlin-1 (DERL1) LDTP11245 10.13  LDD1794 
Derlin-2 (DERL2) LDTP11634 6.77  LDD1794 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 6.36  LDD1794 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 98.36  LDD1794 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 41.93  LDD1794 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 5.90  LDD1794 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 5.58  LDD1794 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 6.54  LDD1794 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 7.31  LDD1794 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 9.58  LDD1794 
Importin subunit alpha-1 (KPNA2) LDTP04501 10.06  LDD1794 
Integral membrane protein 2B (ITM2B) LDTP13833 6.92  LDD1794 
Integral membrane protein 2C (ITM2C) LDTP12451 7.73  LDD1794 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 5.62  LDD1794 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 7.94  LDD1794 
Lysosome membrane protein 2 (SCARB2) LDTP06034 28.44  LDD1794 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 5.50  LDD1794 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 7.57  LDD1794 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 9.65  LDD1794 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 5.86  LDD1794 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 6.06  LDD1794 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 9.45  LDD1794 
Metal transporter CNNM3 (CNNM3) LDTP09144 5.66  LDD1794 
Metaxin-1 (MTX1) LDTP05900 16.34  LDD1794 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 5.70  LDD1794 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 7.46  LDD1794 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 5.66  LDD1794 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 9.13  LDD1794 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 7.36  LDD1794 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 36.25  LDD1794 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1794 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 16.45  LDD1794 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 7.84  LDD1794 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 8.22  LDD1794 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 5.50  LDD1794 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 9.32  LDD1794 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 14.62  LDD1794 
Mpv17-like protein 2 (MPV17L2) LDTP14952 8.22  LDD1794 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 11.71  LDD1794 
Nucleoporin NDC1 (NDC1) LDTP11213 8.94  LDD1794 
Osteopetrosis-associated transmembrane protein 1 (OSTM1) LDTP08327 6.82  LDD1794 
Pannexin-1 (PANX1) LDTP10754 5.50  LDD1794 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 5.94  LDD1794 
Pericentriolar material 1 protein (PCM1) LDTP06331 5.50  LDD1794 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 5.58  LDD1794 
Prosaposin (PSAP) LDTP02215 11.31  LDD1794 
Protein ARV1 (ARV1) LDTP11812 8.69  LDD1794 
Protein FAM8A1 (FAM8A1) LDTP16190 5.54  LDD1794 
Protein GPR107 (GPR107) LDTP07236 20.68  LDD1794 
Protein GPR108 (GPR108) LDTP12383 11.88  LDD1794 
Protein OS-9 (OS9) LDTP05871 7.11  LDD1794 
Protein RFT1 homolog (RFT1) LDTP10073 5.94  LDD1794 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 7.01  LDD1794 
Protein spinster homolog 1 (SPNS1) LDTP11844 6.19  LDD1794 
Protein tweety homolog 3 (TTYH3) LDTP11615 23.59  LDD1794 
Protein wntless homolog (WLS) LDTP07156 12.04  LDD1794 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 8.82  LDD1794 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 10.56  LDD1794 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 12.04  LDD1794 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 9.00  LDD1794 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 13.00  LDD1794 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 6.59  LDD1794 
Sideroflexin-4 (SFXN4) LDTP07531 5.54  LDD1794 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 13.93  LDD1794 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 35.02  LDD1794 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 5.66  LDD1794 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 13.18  LDD1794 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 11.47  LDD1794 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 5.90  LDD1794 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 9.19  LDD1794 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 11.31  LDD1794 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 8.17  LDD1794 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 14.62  LDD1794 
Stomatin (STOM) LDTP03380 10.78  LDD1794 
Stromal interaction molecule 1 (STIM1) LDTP05934 5.74  LDD1794 
Surfeit locus protein 4 (SURF4) LDTP00592 6.82  LDD1794 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 6.96  LDD1794 
Syntaxin-6 (STX6) LDTP00857 16.00  LDD1794 
Tetraspanin-10 (TSPAN10) LDTP15967 18.00  LDD1794 
Tetraspanin-3 (TSPAN3) LDTP16813 17.03  LDD1794 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 20.39  LDD1794 
Translocator protein (TSPO) LDTP03546 7.31  LDD1794 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 16.00  LDD1794 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 6.11  LDD1794 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 10.13  LDD1794 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 12.30  LDD1794 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 5.78  LDD1794 
Transmembrane protein 126A (TMEM126A) LDTP15948 11.31  LDD1794 
Transmembrane protein 160 (TMEM160) LDTP20002 11.79  LDD1794 
Transmembrane protein 199 (TMEM199) LDTP08881 31.34  LDD1794 
Transmembrane protein 205 (TMEM205) LDTP07667 5.86  LDD1794 
Transmembrane protein 245 (TMEM245) LDTP15979 7.06  LDD1794 
Transmembrane protein 87A (TMEM87A) LDTP15481 7.21  LDD1794 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 6.23  LDD1794 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 22.01  LDD1794 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 18.64  LDD1794 
Zinc transporter ZIP11 (SLC39A11) LDTP17682 7.26  LDD1794 
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⏷ Show the Full List of 111 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 7.52  LDD1794 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 8.34  LDD1794 
IgG receptor FcRn large subunit p51 (FCGRT) LDTP04720 13.00  LDD1794 
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79 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.75  LDD1794 
Ankyrin repeat and SOCS box protein 6 (ASB6) LDTP12741 5.82  LDD1794 
Apolipoprotein L2 (APOL2) LDTP11076 40.50  LDD1794 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 9.51  LDD1794 
Centrin-2 (CETN2) LDTP03926 5.70  LDD1794 
Centromere protein K (CENPK) LDTP11143 17.51  LDD1794 
Centrosomal protein 43 (CEP43) LDTP01652 8.88  LDD1794 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.38  LDD1794 
Collectin-12 (COLEC12) LDTP07031 6.92  LDD1794 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 5.66  LDD1794 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 29.65  LDD1794 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 5.54  LDD1794 
Dymeclin (DYM) LDTP08000 9.32  LDD1794 
Dynactin subunit 2 (DCTN2) LDTP05922 6.36  LDD1794 
Dynactin subunit 3 (DCTN3) LDTP01359 6.36  LDD1794 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 7.31  LDD1794 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 10.48  LDD1794 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 11.79  LDD1794 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 12.47  LDD1794 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 22.47  LDD1794 
Ganglioside GM2 activator (GM2A) LDTP02927 11.24  LDD1794 
Golgi apparatus protein 1 (GLG1) LDTP09920 7.46  LDD1794 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 20.25  LDD1794 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 5.78  LDD1794 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 6.15  LDD1794 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 5.98  LDD1794 
Kinetochore protein Spc24 (SPC24) LDTP09069 6.23  LDD1794 
Large proline-rich protein BAG6 (BAG6) LDTP04094 7.78  LDD1794 
Large ribosomal subunit protein bL28m (MRPL28) LDTP05741 5.74  LDD1794 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 11.79  LDD1794 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 10.93  LDD1794 
Membralin (TMEM259) LDTP14939 13.74  LDD1794 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 19.03  LDD1794 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 28.64  LDD1794 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 21.41  LDD1794 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 6.45  LDD1794 
Motile sperm domain-containing protein 2 (MOSPD2) LDTP09255 6.28  LDD1794 
Negative elongation factor C/D (NELFCD) LDTP08594 6.96  LDD1794 
Neudesin (NENF) LDTP13630 9.25  LDD1794 
Neuferricin (CYB5D2) LDTP15623 7.57  LDD1794 
Nucleobindin-1 (NUCB1) LDTP05375 7.89  LDD1794 
Nucleobindin-2 (NUCB2) LDTP05160 41.07  LDD1794 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 6.54  LDD1794 
Nurim (NRM) LDTP08606 12.21  LDD1794 
Optic atrophy 3 protein (OPA3) LDTP16006 8.34  LDD1794 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 8.40  LDD1794 
Protein CEBPZOS (CEBPZOS) LDTP18883 34.54  LDD1794 
Protein FAM114A2 (FAM114A2) LDTP16080 10.48  LDD1794 
Protein FAM162A (FAM162A) LDTP10056 9.32  LDD1794 
Protein jagunal homolog 1 (JAGN1) LDTP08904 8.88  LDD1794 
Protein kish-B (TMEM167B) LDTP12545 5.86  LDD1794 
Protein LYRIC (MTDH) LDTP08224 8.46  LDD1794 
Protein SET (SET) LDTP05277 8.57  LDD1794 
Protein unc-119 homolog B (UNC119B) LDTP00105 13.27  LDD1794 
Protein YIF1A (YIF1A) LDTP01494 7.36  LDD1794 
Protein YIPF4 (YIPF4) LDTP11167 6.36  LDD1794 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 9.92  LDD1794 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 5.90  LDD1794 
Reticulocalbin-2 (RCN2) LDTP06097 7.94  LDD1794 
Reticulon-3 (RTN3) LDTP01522 18.51  LDD1794 
Reticulon-4 (RTN4) LDTP12412 10.63  LDD1794 
Rho GTPase-activating protein 17 (ARHGAP17) LDTP07335 9.85  LDD1794 
RNA-binding protein 39 (RBM39) LDTP06128 14.03  LDD1794 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 7.57  LDD1794 
Small integral membrane protein 12 (SMIM12) LDTP19859 5.66  LDD1794 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 9.13  LDD1794 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 12.13  LDD1794 
Synaptogyrin-2 (SYNGR2) LDTP00859 5.74  LDD1794 
Syntaxin-10 (STX10) LDTP00986 8.94  LDD1794 
Syntaxin-18 (STX18) LDTP13086 11.63  LDD1794 
Tetraspanin-6 (TSPAN6) LDTP14458 22.94  LDD1794 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 10.63  LDD1794 
TraB domain-containing protein (TRABD) LDTP19963 7.46  LDD1794 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 11.79  LDD1794 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 20.11  LDD1794 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 19.03  LDD1794 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 7.57  LDD1794 
YEATS domain-containing protein 4 (YEATS4) LDTP01638 8.34  LDD1794 
Zinc finger protein-like 1 (ZFPL1) LDTP01510 5.78  LDD1794 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1794 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587