Details of the Target

General Information of Target

Target ID LDTP06019
Target Name Cyclin-dependent kinase 13 (CDK13)
Gene Name CDK13
Gene ID 8621
Synonyms
CDC2L; CDC2L5; CHED; KIAA1791; Cyclin-dependent kinase 13; EC 2.7.11.22; EC 2.7.11.23; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; hCDK13; Cholinesterase-related cell division controller
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGE
ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPS
PYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHS
RSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAA
EAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTK
PPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHV
ALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDD
LSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVY
KARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDF
KKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKC
SNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
GCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKL
REEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHEL
WSKKRRRQKQMGMTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLPSSQLKSQGSSNVAPVK
TGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGE
KQTDPSTPQQESSKPLGGIQPSSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGG
IDYQAGDTYVSTSDYKDNFGSSSFSSAPYVSNDGLGSSSAPPLERRSFIGNSDIQSLDNY
STASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQGPGYSQGYRGHIST
STGRGRGRGLPY
Target Type
Literature-reported
Target Bioclass
Enzyme
Family
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Subcellular location
Nucleus speckle
Function
Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
TTD ID
T74839
Uniprot ID
Q14004
DrugMap ID
TTRIM0E
Ensemble ID
ENST00000181839.10
HGNC ID
HGNC:1733
ChEMBL ID
CHEMBL1795192

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
DEL SNV: p.P1447L DBIA    Probe Info 
EFO27 SNV: p.G10E DBIA    Probe Info 
FADU SNV: p.L1092F .
HCT116 Deletion: p.A162PfsTer174 DBIA    Probe Info 
HGC27 SNV: p.A479D DBIA    Probe Info 
IGROV1 Deletion: p.G139VfsTer2 .
JHH6 SNV: p.A93V .
K562 SNV: p.I1116V .
KMCH1 SNV: p.R396L DBIA    Probe Info 
KMS27 SNV: p.K734R .
KYSE150 SNV: p.G1340R DBIA    Probe Info 
KYSE180 SNV: p.A1405T DBIA    Probe Info 
LS180 Deletion: p.K21del .
MCC13 SNV: p.P1265S .
NALM6 SNV: p.V140G DBIA    Probe Info 
NCIH1793 SNV: p.G657V .
NCIH82 SNV: p.Q1259H .
OVK18 Deletion: p.K911NfsTer13 .
SKN SNV: p.L616M DBIA    Probe Info 
SNGM SNV: p.M1476T DBIA    Probe Info 
SW756 SNV: p.K519Ter .
T24 SNV: p.E1019Ter .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C-Sul
 Probe Info  		6.65  LDD0066  [1]
m-APA
 Probe Info  		8.06  LDD0403  [2]
THZ1-DTB
 Probe Info  		C1017(3.84)  LDD0460  [3]
DBIA
 Probe Info  		C987(0.92); C995(0.92); C930(0.88); C934(0.88)  LDD0078  [4]
ATP probe
 Probe Info  		N.A.  LDD0199  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0163  [6]
NAIA_4
 Probe Info  		C701(0.00); C1017(0.00)  LDD2226  [7]
TFBX
 Probe Info  		N.A.  LDD0027  [8]
WYneN
 Probe Info  		N.A.  LDD0021  [9]
IPM
 Probe Info  		N.A.  LDD0005  [9]
AOyne
 Probe Info  		12.70  LDD0443  [10]
NAIA_5
 Probe Info  		N.A.  LDD2223  [7]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-1
 Probe Info  		N.A.  LDD0136  [11]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C900(1.20); C902(1.20); C930(1.14); C934(1.12)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C900(1.40); C930(1.27); C934(1.18); C987(1.09)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C900(0.71); C902(0.71); C930(1.08); C934(1.08)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C900(0.82); C902(0.82); C930(1.00); C934(1.05)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C900(0.91); C902(0.91); C930(0.97); C934(1.10)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C900(0.98); C902(0.98); C930(1.00); C934(1.17)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C900(1.00); C902(1.00); C930(1.09); C934(1.14)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C900(0.93); C902(0.93); C930(1.10); C934(1.28)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C900(0.83); C902(0.83); C930(1.06); C934(1.19)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C900(0.60); C902(0.94); C930(1.14); C934(1.19)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C900(1.52); C902(0.88); C930(1.07); C934(1.12)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C900(1.24); C902(0.71); C930(1.01); C934(0.95)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C900(1.78); C930(1.14); C934(1.03); C987(1.01)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C900(1.09); C902(0.80); C930(1.07); C934(1.04)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C900(0.97); C902(0.81); C930(0.99); C934(1.03)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C900(0.76); C902(0.82); C930(1.08); C934(1.22)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C900(0.92); C902(0.92); C930(0.95); C934(0.94)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C900(1.16); C902(1.16); C930(1.06); C934(1.04)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C900(1.47); C902(1.47); C930(1.29); C934(1.23)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C900(1.44); C902(1.44); C930(1.28); C934(1.25)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C900(1.33); C902(1.33); C930(1.04); C934(1.01)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C900(1.25); C902(1.25); C930(1.05); C934(1.04)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C900(1.10); C902(1.10); C930(1.07); C934(1.05)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C900(1.79); C930(1.00); C934(0.95); C987(1.09)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C900(1.09); C902(1.09); C930(1.17); C934(1.14)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C900(1.49); C902(1.49); C930(1.09); C934(1.00)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C900(1.32); C902(1.32); C930(1.02); C934(1.02)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C900(1.23); C902(1.23); C930(1.24); C934(1.09)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C900(1.22); C902(1.22); C930(1.16); C934(1.07)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C900(1.34); C902(1.34); C930(1.10); C934(1.03)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C900(1.37); C902(1.37); C930(1.22); C934(1.16)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C900(1.33); C902(1.33); C930(1.13); C934(1.07)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C930(1.24); C934(1.21); C987(1.58); C995(1.58)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C930(1.00); C934(1.05); C987(1.17); C995(1.17)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C930(1.18); C934(1.18); C987(1.50); C995(1.50)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C930(1.02); C934(1.13); C987(1.28); C995(1.28)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C930(0.91); C934(1.03); C987(1.38); C995(1.38)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C930(1.04); C934(1.10); C987(1.44); C995(1.44)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C930(1.17); C934(1.23); C987(1.54); C995(1.54)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C930(1.05); C934(1.14); C987(1.73); C995(1.73)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C930(1.05); C934(1.11); C987(1.20); C995(1.20)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C930(1.01); C934(1.11); C987(1.15); C995(1.15)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C930(0.96); C934(1.23); C987(1.44); C995(1.44)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C930(1.03); C934(1.13); C987(1.69); C995(1.69)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C900(1.40); C930(1.15); C934(1.07); C987(1.03)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C930(1.07); C934(1.23); C987(1.59); C995(1.59)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C930(1.07); C934(1.28); C987(1.41); C995(1.41)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C930(0.88); C934(0.98); C987(1.38); C995(1.38)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C930(0.98); C934(0.89); C987(0.94); C995(0.94)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C987(1.06); C995(1.07); C930(1.09); C934(1.13)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C995(0.96); C930(0.98); C987(0.98); C934(0.99)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C987(1.03); C995(1.06); C930(1.14); C934(1.16)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C995(0.87); C987(0.97); C934(1.20); C930(1.21)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C987(1.04); C995(1.05); C934(1.46); C930(1.53)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C987(0.87); C995(0.92); C930(1.26); C934(1.28)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C934(1.04); C930(1.06); C987(1.09); C995(1.09)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C987(0.79); C995(0.82); C930(0.93); C934(0.97)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C995(0.96); C987(1.01); C934(1.02); C930(1.08)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C995(0.93); C987(0.97); C930(1.18); C934(1.21)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C987(0.89); C995(0.93); C930(1.66); C934(1.72)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C930(1.13); C934(1.10); C987(1.07); C995(1.01)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C930(1.27); C934(1.27); C987(1.03); C995(0.96)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C930(0.97); C934(0.98); C987(1.01); C995(1.02)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C930(1.08); C934(1.06); C987(0.95); C995(0.95)  LDD2161  [4]
 LDCM0276  AC17 HCT 116 C987(1.03); C995(1.03); C930(1.11); C934(1.11)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C987(1.12); C995(1.12); C930(1.29); C934(1.32)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C987(1.00); C995(1.00); C930(1.22); C934(1.23)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C930(1.01); C934(1.06); C987(1.18); C995(1.18)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C987(1.01); C995(1.01); C934(1.11); C930(1.13)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C934(1.17); C930(1.18); C987(1.22); C995(1.22)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C930(1.02); C934(1.03); C987(1.12); C995(1.12)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C987(0.95); C995(0.95); C930(1.15); C934(1.19)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C987(0.92); C995(0.92); C930(1.09); C934(1.15)  LDD0601  [4]
 LDCM0285  AC25 HCT 116 C934(0.98); C930(1.01); C987(1.14); C995(1.14)  LDD0602  [4]
 LDCM0286  AC26 HCT 116 C934(0.94); C987(0.99); C995(0.99); C930(1.04)  LDD0603  [4]
 LDCM0287  AC27 HCT 116 C934(0.99); C987(1.02); C995(1.02); C930(1.09)  LDD0604  [4]
 LDCM0288  AC28 HCT 116 C934(1.00); C987(1.00); C995(1.00); C930(1.10)  LDD0605  [4]
 LDCM0289  AC29 HCT 116 C987(0.94); C995(0.94); C934(1.02); C930(1.12)  LDD0606  [4]
 LDCM0290  AC3 HCT 116 C934(1.04); C930(1.05); C987(1.21); C995(1.21)  LDD0607  [4]
 LDCM0291  AC30 HCT 116 C987(0.95); C995(0.95); C934(1.01); C930(1.14)  LDD0608  [4]
 LDCM0292  AC31 HCT 116 C987(0.87); C995(0.87); C934(1.07); C930(1.14)  LDD0609  [4]
 LDCM0293  AC32 HCT 116 C987(0.84); C995(0.84); C934(1.11); C930(1.20)  LDD0610  [4]
 LDCM0294  AC33 HCT 116 C987(0.96); C995(0.96); C934(1.10); C930(1.14)  LDD0611  [4]
 LDCM0295  AC34 HCT 116 C987(0.89); C995(0.89); C934(1.13); C930(1.24)  LDD0612  [4]
 LDCM0296  AC35 HCT 116 C930(0.86); C934(0.87); C987(1.07); C995(1.07)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C930(0.93); C934(0.97); C987(1.09); C995(1.09)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C930(0.90); C934(0.94); C987(1.15); C995(1.15)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C987(1.04); C995(1.04); C930(1.07); C934(1.09)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C930(1.07); C934(1.07); C987(1.17); C995(1.17)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C934(1.11); C930(1.13); C987(1.36); C995(1.36)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C930(1.05); C934(1.09); C987(1.36); C995(1.36)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C987(0.89); C995(0.89); C930(1.03); C934(1.11)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C987(0.96); C995(0.96); C930(1.04); C934(1.08)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C930(1.03); C934(1.05); C987(1.14); C995(1.14)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C930(0.99); C934(1.04); C987(1.07); C995(1.07)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C930(1.17); C987(1.18); C995(1.18); C934(1.21)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C987(0.93); C995(0.93); C934(1.04); C930(1.09)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C934(0.93); C930(0.96); C987(0.99); C995(0.99)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C987(0.87); C995(0.87); C934(1.05); C930(1.09)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C987(1.01); C995(1.01); C930(1.19); C934(1.21)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C934(1.10); C930(1.12); C987(1.19); C995(1.19)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C987(0.90); C995(0.90); C930(1.25); C934(1.26)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C987(0.85); C995(0.85); C934(0.87); C930(0.91)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C987(0.98); C995(0.98); C934(1.01); C930(1.08)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C987(1.04); C995(1.04); C934(1.08); C930(1.16)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C987(0.98); C995(0.98); C934(1.02); C930(1.12)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C987(1.08); C995(1.08); C930(1.23); C934(1.27)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C987(1.14); C995(1.14); C930(1.39); C934(1.40)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C900(1.05); C902(1.05); C987(1.06); C995(1.06)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C987(1.10); C995(1.10); C900(1.15); C902(1.15)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C987(1.06); C995(1.06); C930(1.14); C934(1.18)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C987(1.04); C995(1.04); C930(1.06); C934(1.08)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C930(1.05); C934(1.16); C900(1.18); C902(1.18)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C930(1.10); C934(1.10); C900(1.28); C902(1.28)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C930(1.27); C934(1.32); C900(1.51); C902(1.51)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C987(0.86); C995(0.86); C930(1.10); C934(1.27)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C900(1.12); C902(1.12); C930(1.24); C987(1.27)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C930(1.23); C934(1.29); C987(1.37); C995(1.37)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C987(1.11); C995(1.11); C930(1.19); C934(1.24)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C987(1.30); C995(1.30); C930(1.30); C934(1.40)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C934(1.16); C930(1.19); C987(1.22); C995(1.22)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C934(1.11); C930(1.14); C987(1.27); C995(1.27)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C987(0.86); C995(0.86); C934(1.10); C930(1.15)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C934(1.13); C987(1.14); C995(1.14); C930(1.19)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C930(1.06); C934(1.07); C987(1.38); C995(1.38)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C934(1.04); C930(1.05); C987(1.21); C995(1.21)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C930(1.27); C934(1.28); C987(1.61); C995(1.61)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C987(1.27); C995(1.27); C934(1.33); C930(1.33)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C987(1.39); C995(1.39); C930(1.40); C934(1.41)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C930(1.17); C934(1.18); C987(1.53); C995(1.53)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C934(1.17); C930(1.17); C987(1.51); C995(1.51)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C934(0.99); C930(1.00); C987(1.08); C995(1.08)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C934(1.04); C930(1.05); C987(1.24); C995(1.24)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C987(0.95); C995(0.95); C934(1.09); C900(1.11)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C930(1.05); C987(1.06); C995(1.06); C934(1.15)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C987(0.98); C995(0.98); C930(1.05); C934(1.07)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C987(1.32); C995(1.32); C934(1.62); C930(1.63)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C934(1.34); C987(1.38); C995(1.38); C930(1.39)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C934(1.19); C930(1.22); C987(1.24); C995(1.24)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C934(1.02); C930(1.05); C987(1.13); C995(1.13)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C934(1.02); C930(1.07); C987(1.15); C995(1.15)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C987(0.96); C995(0.96); C934(1.12); C930(1.17)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C987(0.95); C995(0.95); C934(1.08); C930(1.16)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C934(1.35); C987(1.39); C995(1.39); C930(1.41)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C934(0.94); C930(1.01); C987(1.26); C995(1.26)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C934(1.27); C930(1.27); C987(1.55); C995(1.55)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C934(1.17); C930(1.20); C987(1.25); C995(1.25)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C987(0.98); C995(0.98); C934(1.02); C930(1.05)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C987(1.03); C995(1.03); C934(1.13); C930(1.15)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C934(0.94); C930(1.02); C987(1.05); C995(1.05)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C930(1.07); C934(1.07); C987(1.35); C995(1.35)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C987(0.99); C995(0.99); C934(1.17); C930(1.19)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C900(1.05); C902(1.05); C987(1.18); C995(1.18)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C987(0.74); C995(0.74); C900(0.87); C902(0.87)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C900(1.16); C930(0.96); C934(0.95); C987(1.09)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C934(1.01); C987(1.03); C995(1.03); C930(1.05)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C987(1.10); C995(1.10); C934(1.31); C930(1.34)  LDD0592  [4]
 LDCM0156  Aniline NCI-H1299 8.06  LDD0403  [2]
 LDCM0020  ARS-1620 HCC44 C987(0.92); C995(0.92); C930(0.88); C934(0.88)  LDD0078  [4]
 LDCM0367  CL1 HCT 116 C987(0.74); C995(0.74); C930(1.42); C934(1.42)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C987(1.17); C995(1.17); C930(1.96); C934(1.96)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C930(1.04); C934(1.05); C900(1.14); C902(1.14)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C987(1.06); C995(1.06); C934(1.11); C930(1.13)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C987(0.92); C995(0.92); C934(1.09); C930(1.16)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C987(1.05); C995(1.05); C934(1.06); C930(1.12)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C987(0.99); C995(0.99); C930(1.08); C934(1.09)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C987(0.99); C995(0.99); C934(1.23); C930(1.24)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C987(1.23); C995(1.23); C930(1.41); C934(1.43)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C987(1.02); C995(1.02); C930(1.28); C934(1.34)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C987(1.09); C995(1.09); C930(1.44); C934(1.49)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C987(1.04); C995(1.04); C934(1.23); C930(1.23)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C987(1.21); C995(1.21); C930(1.29); C934(1.29)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C987(0.97); C995(0.97); C934(1.56); C930(1.57)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C987(0.97); C995(0.97); C930(1.37); C934(1.44)  LDD0698  [4]
 LDCM0382  CL112 HCT 116 C987(0.85); C995(0.85); C934(1.00); C930(1.13)  LDD0699  [4]
 LDCM0383  CL113 HCT 116 C987(0.85); C995(0.85); C934(1.05); C930(1.17)  LDD0700  [4]
 LDCM0384  CL114 HCT 116 C987(0.85); C995(0.85); C934(1.14); C930(1.25)  LDD0701  [4]
 LDCM0385  CL115 HCT 116 C987(0.88); C995(0.88); C934(1.14); C930(1.25)  LDD0702  [4]
 LDCM0386  CL116 HCT 116 C987(0.97); C995(0.97); C934(0.98); C930(1.05)  LDD0703  [4]
 LDCM0387  CL117 HCT 116 C987(1.36); C995(1.36); C930(1.75); C934(1.95)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C987(0.99); C995(0.99); C930(1.02); C934(1.03)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C930(0.99); C934(1.03); C987(1.08); C995(1.08)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C930(1.18); C934(1.18); C987(1.38); C995(1.38)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C930(1.03); C934(1.06); C987(1.06); C995(1.06)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C930(0.98); C934(1.25); C987(1.39); C995(1.39)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C987(0.90); C995(0.90); C934(1.06); C930(1.17)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C987(1.06); C995(1.06); C934(1.64); C930(1.73)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C934(1.35); C930(1.51); C987(1.55); C995(1.55)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C900(1.02); C902(1.02); C930(1.05); C934(1.10)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C987(0.80); C995(0.80); C930(1.18); C934(1.26)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C987(0.84); C995(0.84); C930(0.94); C934(1.03)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C900(1.15); C902(1.15); C934(1.20); C930(1.21)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C987(1.02); C995(1.02); C930(1.30); C934(1.30)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C987(1.00); C995(1.00); C930(1.18); C934(1.18)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C987(1.03); C995(1.03); C930(1.38); C934(1.38)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C987(0.90); C995(0.90); C930(1.14); C934(1.22)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C987(0.98); C995(0.98); C930(1.28); C934(1.42)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C987(0.89); C995(0.89); C930(1.08); C934(1.10)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C930(1.05); C987(1.07); C995(1.07); C934(1.11)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C987(0.99); C995(0.99); C930(1.07); C934(1.07)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C930(1.13); C934(1.25); C987(1.39); C995(1.39)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C987(1.12); C995(1.12); C930(1.88); C934(2.11)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C987(1.55); C995(1.55); C930(1.72); C934(1.84)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C987(0.83); C995(0.83); C930(1.01); C934(1.06)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C987(1.19); C995(1.19); C930(1.20); C934(1.27)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C930(1.29); C934(1.38); C987(0.95); C995(0.95)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C930(1.12); C934(1.22); C987(0.94); C995(0.94)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C930(1.04); C934(1.10); C987(1.43); C995(1.43)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C930(1.23); C934(1.32); C987(1.26); C995(1.26)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C930(1.11); C934(1.17); C987(1.12); C995(1.12)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C930(0.86); C934(0.86); C987(1.29); C995(1.29)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C930(1.01); C934(1.07); C987(1.09); C995(1.09)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C930(1.28); C934(1.24); C987(1.00); C995(1.00)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C930(1.32); C934(1.20); C987(0.96); C995(0.96)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C930(3.01); C934(3.41); C987(0.89); C995(0.89)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C930(1.49); C934(1.53); C987(0.88); C995(0.88)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C930(1.35); C934(1.29); C987(0.99); C995(0.99)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C930(1.27); C934(1.29); C987(0.97); C995(0.97)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C930(1.46); C934(1.36); C987(1.22); C995(1.22)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C930(1.49); C934(1.40); C987(1.04); C995(1.04)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C930(1.16); C934(1.16); C987(0.90); C995(0.90)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C930(2.00); C934(1.62); C987(0.90); C995(0.90)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C930(1.25); C934(1.15); C987(0.97); C995(0.97)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C930(1.77); C934(1.64); C987(0.88); C995(0.88)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C930(1.50); C934(1.36); C987(1.08); C995(1.08)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C930(1.82); C934(1.64); C987(1.10); C995(1.10)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C930(1.93); C934(1.74); C987(0.96); C995(0.96)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C930(1.03); C934(0.94); C987(0.86); C995(0.86)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C930(1.07); C934(1.04); C987(0.75); C995(0.75)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C930(0.93); C934(0.92); C987(0.82); C995(0.82)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C930(1.02); C934(1.02); C987(1.03); C995(1.03)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C930(1.02); C934(1.02); C987(1.01); C995(1.01)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C930(0.98); C934(0.93); C987(0.92); C995(0.92)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C930(0.92); C934(0.91); C987(1.03); C995(1.03)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C930(0.91); C934(0.83); C987(0.98); C995(0.98)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C930(1.06); C934(1.01); C987(0.87); C995(0.87)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C930(1.04); C934(1.09); C987(0.93); C995(0.93)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C930(0.89); C934(0.94); C987(1.00); C995(1.00)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C930(1.15); C934(1.17); C987(0.91); C995(0.91)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C930(1.24); C934(1.22); C987(0.90); C995(0.90)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C930(0.93); C934(0.91); C987(0.88); C995(0.88)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C930(0.99); C934(0.97); C987(0.95); C995(0.95)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C930(1.05); C934(1.05); C987(1.01); C995(1.01)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C930(1.05); C934(1.01); C987(0.87); C995(0.87)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C930(1.02); C934(0.97); C987(0.98); C995(0.98)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C930(1.17); C934(1.14); C987(0.97); C995(0.97)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C930(1.09); C934(1.04); C987(1.03); C995(1.03)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C930(1.35); C934(1.30); C987(1.03); C995(1.03)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C930(1.12); C934(1.11); C987(0.98); C995(0.98)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C930(1.66); C934(1.64); C987(1.13); C995(1.13)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C930(1.14); C934(1.14); C987(0.99); C995(0.99)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C930(1.27); C934(1.22); C987(0.97); C995(0.97)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C930(1.25); C934(1.19); C987(0.98); C995(0.98)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C930(1.04); C934(1.04); C987(1.13); C995(1.13)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C930(1.06); C934(1.01); C987(1.05); C995(1.05)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C930(1.12); C934(1.05); C987(0.90); C995(0.90)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C930(1.00); C934(0.94); C987(0.90); C995(0.90)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C930(1.21); C934(1.16); C987(0.95); C995(0.95)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C930(1.12); C934(1.03); C987(0.97); C995(0.97)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C900(1.01); C902(1.01); C930(1.17); C934(1.15)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C900(0.85); C902(0.85); C930(1.31); C934(1.22)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C900(0.92); C902(0.92); C930(1.20); C934(1.19)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C900(1.14); C902(1.14); C930(1.26); C934(1.26)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C930(2.27); C934(2.27); C987(1.13); C995(1.13)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C900(0.91); C902(0.91); C930(1.12); C934(1.07)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C900(0.92); C902(0.92); C930(1.20); C934(1.18)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C900(1.59); C902(1.59); C930(1.46); C934(1.43)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C900(1.26); C902(1.26); C930(1.28); C934(1.27)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C900(1.72); C902(1.72); C930(1.71); C934(1.64)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C900(1.00); C902(1.00); C930(1.03); C934(1.02)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C900(1.02); C902(1.02); C930(1.17); C934(1.14)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C900(1.04); C902(1.04); C930(1.29); C934(1.27)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C900(1.29); C902(1.29); C930(1.34); C934(1.33)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C900(2.12); C902(2.12); C930(1.61); C934(1.62)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C930(0.95); C934(0.95); C987(1.02); C995(1.02)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C900(0.84); C902(0.84); C930(3.19); C934(2.80)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C900(0.97); C902(0.97); C930(1.13); C934(1.15)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C900(1.06); C902(1.06); C930(1.23); C934(1.26)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C900(0.94); C902(0.94); C930(1.09); C934(1.08)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C900(1.00); C902(1.00); C930(1.39); C934(1.40)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C900(1.01); C902(1.01); C930(1.33); C934(1.35)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C900(1.09); C902(1.09); C930(1.07); C934(1.07)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C900(1.22); C902(1.22); C930(1.28); C934(1.30)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C900(1.27); C902(1.27); C930(1.30); C934(1.31)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C900(1.09); C902(1.09); C930(1.38); C934(1.40)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C840(0.96); C644(0.95); C828(0.95); C934(0.98)  LDD1698  [12]
 LDCM0572  Fragment10 Ramos C840(1.44)  LDD2189  [13]
 LDCM0573  Fragment11 Ramos C840(6.33)  LDD2190  [13]
 LDCM0574  Fragment12 Ramos C840(1.42)  LDD2191  [13]
 LDCM0579  Fragment20 Ramos C840(2.28)  LDD2194  [13]
 LDCM0580  Fragment21 Ramos C840(0.89)  LDD2195  [13]
 LDCM0582  Fragment23 Ramos C840(0.75)  LDD2196  [13]
 LDCM0578  Fragment27 Ramos C840(0.98)  LDD2197  [13]
 LDCM0586  Fragment28 Ramos C840(0.80)  LDD2198  [13]
 LDCM0588  Fragment30 Ramos C840(0.96)  LDD2199  [13]
 LDCM0589  Fragment31 Ramos C840(1.07)  LDD2200  [13]
 LDCM0590  Fragment32 Ramos C840(1.35)  LDD2201  [13]
 LDCM0468  Fragment33 HCT 116 C930(1.30); C934(1.26); C987(0.94); C995(0.94)  LDD0785  [4]
 LDCM0596  Fragment38 Ramos C840(1.16)  LDD2203  [13]
 LDCM0427  Fragment51 HCT 116 C930(3.12); C934(2.18); C987(0.95); C995(0.95)  LDD0744  [4]
 LDCM0610  Fragment52 Ramos C840(1.36)  LDD2204  [13]
 LDCM0614  Fragment56 Ramos C840(1.37)  LDD2205  [13]
 LDCM0571  Fragment9 Ramos C840(2.14)  LDD2188  [13]
 LDCM0022  KB02 HCT 116 C987(20.00); C995(20.00); C930(20.00); C1017(1.89)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C987(20.00); C995(20.00); C930(18.99); C1017(1.89)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C987(9.55); C995(9.55); C930(8.34); C1017(1.99)  LDD0082  [4]
 LDCM0021  THZ1 HeLa S3 C1017(3.84)  LDD0460  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) MAM33 family Q07021
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclin-K (CCNK) Cyclin family O75909

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Thz531 Small molecular drug D7RK2M

References

1 Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells. Anal Chem. 2022 Mar 15;94(10):4366-4372. doi: 10.1021/acs.analchem.1c05129. Epub 2022 Mar 4.
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
9 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
10 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
11 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
12 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
13 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578