Details of the Target

General Information of Target

Target ID LDTP09118
Target Name SLAIN motif-containing protein 1 (SLAIN1)
Gene Name SLAIN1
Gene ID 122060
Synonyms
C13orf32; SLAIN motif-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MMAEQVKCASAGVSSGAGSGPVVNAELEVKKLQELVRKLEKQNEQLRSRAASAAAAPHLL
LLPPPPPAAPPPAGLQPLGPRSPPAATATAAASGGLGPAFPGTFCLPSPAPSLLCSLAQP
PEAPFVYFKPAAGFFGAGGGGPEPGGAGTPPGAAAAPPSPPPTLLDEVELLDLESVAAWR
DEDDYTWLYIGSSKTFTSSEKSLTPLQWCRHVLDNPTPEMEAARRSLCFRLEQGYTSRGS
PLSPQSSIDSELSTSELEDDSISMGYKLQDLTDVQIMARLQEESLRQDYASTSASVSRHS
SSVSLSSGKKGTCSDQEYDQYSLEDEEEFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRE
CRRSPSSQYFPSNNYQQQQYYSPQAQTPDQQPNRTNGDKLRRSMPNLARMPSTTAISSNI
SSPVTVRNSQSFDSSLHGAGNGISRIQSCIPSPGQLQHRVHSVGHFPVSIRQPLKATAYV
SPTVQGSSNMPLSNGLQLYSNTGIPTPNKAAASGIMGRSALPRPSLAINGSNLPRSKIAQ
PVRSFLQPPKPLSSLSTLRDGNWRDGCY
Target Bioclass
Other
Family
SLAIN motif-containing family
Subcellular location
Cytoplasm, cytoskeleton
Function Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation.
Uniprot ID
Q8ND83
Ensemble ID
ENST00000314070.9
HGNC ID
HGNC:26387

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C67(2.59)  LDD3434  [1]
DA-P3
 Probe Info  		4.58  LDD0179  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [3]
VSF
 Probe Info  		N.A.  LDD0007  [4]
Phosphinate-6
 Probe Info  		C8(0.00); C342(0.00)  LDD0018  [5]
AOyne
 Probe Info  		11.50  LDD0443  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C313(3.91)  LDD0372  [7]
 LDCM0214  AC1 HEK-293T C209(0.89)  LDD0812  [8]
 LDCM0215  AC10 HEK-293T C8(1.17); C449(0.95)  LDD1508  [9]
 LDCM0226  AC11 HEK-293T C8(1.18)  LDD1509  [9]
 LDCM0230  AC113 PaTu 8988t C209(0.77)  LDD1109  [8]
 LDCM0231  AC114 PaTu 8988t C209(0.95)  LDD1110  [8]
 LDCM0232  AC115 PaTu 8988t C209(1.28)  LDD1111  [8]
 LDCM0233  AC116 PaTu 8988t C209(0.61)  LDD1112  [8]
 LDCM0234  AC117 PaTu 8988t C209(0.91)  LDD1113  [8]
 LDCM0235  AC118 PaTu 8988t C209(1.02)  LDD1114  [8]
 LDCM0236  AC119 PaTu 8988t C209(0.76)  LDD1115  [8]
 LDCM0237  AC12 HEK-293T C8(1.11)  LDD1510  [9]
 LDCM0238  AC120 PaTu 8988t C209(0.69)  LDD1117  [8]
 LDCM0239  AC121 PaTu 8988t C209(0.96)  LDD1118  [8]
 LDCM0240  AC122 PaTu 8988t C209(1.31)  LDD1119  [8]
 LDCM0241  AC123 PaTu 8988t C209(0.66)  LDD1120  [8]
 LDCM0242  AC124 PaTu 8988t C209(0.78)  LDD1121  [8]
 LDCM0243  AC125 PaTu 8988t C209(0.69)  LDD1122  [8]
 LDCM0244  AC126 PaTu 8988t C209(0.73)  LDD1123  [8]
 LDCM0245  AC127 PaTu 8988t C209(0.82)  LDD1124  [8]
 LDCM0259  AC14 HEK-293T C8(1.25)  LDD1512  [9]
 LDCM0270  AC15 HEK-293T C8(1.03); C449(1.16)  LDD1513  [9]
 LDCM0276  AC17 HEK-293T C209(0.94); C449(1.04)  LDD0874  [8]
 LDCM0277  AC18 HEK-293T C209(1.09); C449(1.06)  LDD0875  [8]
 LDCM0278  AC19 HEK-293T C209(1.26); C449(1.60)  LDD0876  [8]
 LDCM0279  AC2 HEK-293T C209(0.90)  LDD0877  [8]
 LDCM0280  AC20 HEK-293T C209(1.14); C449(1.08)  LDD0878  [8]
 LDCM0281  AC21 HEK-293T C209(0.98); C449(0.87)  LDD0879  [8]
 LDCM0282  AC22 HEK-293T C209(0.82); C449(0.97)  LDD0880  [8]
 LDCM0283  AC23 HEK-293T C209(1.09); C449(1.24)  LDD0881  [8]
 LDCM0284  AC24 HEK-293T C209(0.83); C449(0.89)  LDD0882  [8]
 LDCM0285  AC25 HEK-293T C209(1.12)  LDD0883  [8]
 LDCM0286  AC26 HEK-293T C209(1.07)  LDD0884  [8]
 LDCM0287  AC27 HEK-293T C209(0.97)  LDD0885  [8]
 LDCM0288  AC28 HEK-293T C209(1.15)  LDD0886  [8]
 LDCM0289  AC29 HEK-293T C209(1.46)  LDD0887  [8]
 LDCM0290  AC3 HEK-293T C209(1.04)  LDD0888  [8]
 LDCM0291  AC30 HEK-293T C209(1.08)  LDD0889  [8]
 LDCM0292  AC31 HEK-293T C209(0.96)  LDD0890  [8]
 LDCM0293  AC32 HEK-293T C209(1.21)  LDD0891  [8]
 LDCM0294  AC33 HEK-293T C209(1.02)  LDD0892  [8]
 LDCM0295  AC34 HEK-293T C209(0.98)  LDD0893  [8]
 LDCM0296  AC35 HEK-293T C209(1.12); C449(1.32)  LDD0894  [8]
 LDCM0297  AC36 HEK-293T C209(1.24); C449(1.25)  LDD0895  [8]
 LDCM0298  AC37 HEK-293T C209(1.06); C449(1.24)  LDD0896  [8]
 LDCM0299  AC38 HEK-293T C209(1.09); C449(1.05)  LDD0897  [8]
 LDCM0300  AC39 HEK-293T C209(1.14); C449(1.17)  LDD0898  [8]
 LDCM0301  AC4 HEK-293T C209(0.95)  LDD0899  [8]
 LDCM0302  AC40 HEK-293T C209(0.97); C449(1.02)  LDD0900  [8]
 LDCM0303  AC41 HEK-293T C209(1.11); C449(1.21)  LDD0901  [8]
 LDCM0304  AC42 HEK-293T C209(0.97); C449(0.96)  LDD0902  [8]
 LDCM0305  AC43 HEK-293T C209(1.05); C449(1.10)  LDD0903  [8]
 LDCM0306  AC44 HEK-293T C209(1.11); C449(1.20)  LDD0904  [8]
 LDCM0307  AC45 HEK-293T C209(1.08); C449(1.14)  LDD0905  [8]
 LDCM0308  AC46 HEK-293T C209(0.82); C449(0.75)  LDD0906  [8]
 LDCM0309  AC47 HEK-293T C209(0.84); C449(0.61)  LDD0907  [8]
 LDCM0310  AC48 HEK-293T C209(0.82); C449(0.65)  LDD0908  [8]
 LDCM0311  AC49 HEK-293T C209(0.90); C449(0.66)  LDD0909  [8]
 LDCM0312  AC5 HEK-293T C209(1.12)  LDD0910  [8]
 LDCM0313  AC50 HEK-293T C209(0.82); C449(0.63)  LDD0911  [8]
 LDCM0314  AC51 HEK-293T C209(0.74); C449(0.67)  LDD0912  [8]
 LDCM0315  AC52 HEK-293T C209(0.81); C449(0.70)  LDD0913  [8]
 LDCM0316  AC53 HEK-293T C209(0.89); C449(0.93)  LDD0914  [8]
 LDCM0317  AC54 HEK-293T C209(0.80); C449(0.65)  LDD0915  [8]
 LDCM0318  AC55 HEK-293T C209(0.79); C449(0.67)  LDD0916  [8]
 LDCM0319  AC56 HEK-293T C209(0.84); C449(0.67)  LDD0917  [8]
 LDCM0320  AC57 HEK-293T C449(0.97); C209(1.05)  LDD1559  [9]
 LDCM0321  AC58 HEK-293T C8(1.01); C449(0.76)  LDD1560  [9]
 LDCM0322  AC59 HEK-293T C8(1.05)  LDD1561  [9]
 LDCM0323  AC6 HEK-293T C8(1.03)  LDD1562  [9]
 LDCM0324  AC60 HEK-293T C8(1.00)  LDD1563  [9]
 LDCM0325  AC61 HEK-293T C8(1.05); C449(1.05)  LDD1564  [9]
 LDCM0326  AC62 HEK-293T C8(1.12)  LDD1565  [9]
 LDCM0327  AC63 HEK-293T C8(1.02); C449(1.15)  LDD1566  [9]
 LDCM0328  AC64 HEK-293T C8(0.96)  LDD1567  [9]
 LDCM0334  AC7 HEK-293T C8(1.00); C449(1.16)  LDD1568  [9]
 LDCM0345  AC8 HEK-293T C8(0.79)  LDD1569  [9]
 LDCM0248  AKOS034007472 HEK-293T C8(1.03); C449(1.07)  LDD1511  [9]
 LDCM0356  AKOS034007680 HEK-293T C449(1.01); C209(1.00)  LDD1570  [9]
 LDCM0275  AKOS034007705 HEK-293T C8(0.90)  LDD1514  [9]
 LDCM0367  CL1 HEK-293T C209(0.82)  LDD0965  [8]
 LDCM0368  CL10 HEK-293T C209(1.02)  LDD0966  [8]
 LDCM0369  CL100 HEK-293T C209(0.93)  LDD0967  [8]
 LDCM0370  CL101 HEK-293T C8(1.08)  LDD1574  [9]
 LDCM0371  CL102 HEK-293T C8(1.12)  LDD1575  [9]
 LDCM0372  CL103 HEK-293T C8(1.09)  LDD1576  [9]
 LDCM0373  CL104 HEK-293T C449(0.87)  LDD1577  [9]
 LDCM0374  CL105 HEK-293T C209(0.76); C449(0.86)  LDD0972  [8]
 LDCM0375  CL106 HEK-293T C209(0.76); C449(0.83)  LDD0973  [8]
 LDCM0376  CL107 HEK-293T C209(0.89); C449(0.92)  LDD0974  [8]
 LDCM0377  CL108 HEK-293T C209(1.02); C449(1.19)  LDD0975  [8]
 LDCM0378  CL109 HEK-293T C209(0.87); C449(0.85)  LDD0976  [8]
 LDCM0379  CL11 HEK-293T C209(1.24)  LDD0977  [8]
 LDCM0380  CL110 HEK-293T C209(0.76); C449(0.87)  LDD0978  [8]
 LDCM0381  CL111 HEK-293T C209(0.93); C449(1.02)  LDD0979  [8]
 LDCM0382  CL112 HEK-293T C209(1.11)  LDD0980  [8]
 LDCM0383  CL113 HEK-293T C209(1.29)  LDD0981  [8]
 LDCM0384  CL114 HEK-293T C209(0.86)  LDD0982  [8]
 LDCM0385  CL115 HEK-293T C209(0.97)  LDD0983  [8]
 LDCM0386  CL116 HEK-293T C209(1.36)  LDD0984  [8]
 LDCM0387  CL117 HEK-293T C209(1.06); C449(1.07)  LDD0985  [8]
 LDCM0388  CL118 HEK-293T C209(1.11); C449(1.12)  LDD0986  [8]
 LDCM0389  CL119 HEK-293T C209(1.02); C449(1.06)  LDD0987  [8]
 LDCM0390  CL12 HEK-293T C209(1.09)  LDD0988  [8]
 LDCM0391  CL120 HEK-293T C209(1.04); C449(1.06)  LDD0989  [8]
 LDCM0392  CL121 HEK-293T C209(0.76); C449(0.57)  LDD0990  [8]
 LDCM0393  CL122 HEK-293T C209(0.73); C449(0.68)  LDD0991  [8]
 LDCM0394  CL123 HEK-293T C209(0.67); C449(0.60)  LDD0992  [8]
 LDCM0395  CL124 HEK-293T C209(0.80); C449(0.52)  LDD0993  [8]
 LDCM0396  CL125 HEK-293T C8(0.91)  LDD1600  [9]
 LDCM0397  CL126 HEK-293T C8(0.94)  LDD1601  [9]
 LDCM0398  CL127 HEK-293T C8(1.10)  LDD1602  [9]
 LDCM0399  CL128 HEK-293T C449(1.04)  LDD1603  [9]
 LDCM0400  CL13 HEK-293T C209(1.42)  LDD0998  [8]
 LDCM0401  CL14 HEK-293T C209(0.93)  LDD0999  [8]
 LDCM0402  CL15 HEK-293T C209(0.80)  LDD1000  [8]
 LDCM0403  CL16 PaTu 8988t C209(0.97)  LDD1282  [8]
 LDCM0404  CL17 PaTu 8988t C209(0.85)  LDD1283  [8]
 LDCM0405  CL18 PaTu 8988t C209(1.11)  LDD1284  [8]
 LDCM0406  CL19 PaTu 8988t C209(1.13)  LDD1285  [8]
 LDCM0407  CL2 HEK-293T C209(1.04)  LDD1005  [8]
 LDCM0408  CL20 PaTu 8988t C209(1.33)  LDD1287  [8]
 LDCM0409  CL21 PaTu 8988t C209(1.20)  LDD1288  [8]
 LDCM0410  CL22 PaTu 8988t C209(1.07)  LDD1289  [8]
 LDCM0411  CL23 PaTu 8988t C209(0.98)  LDD1290  [8]
 LDCM0412  CL24 PaTu 8988t C209(0.86)  LDD1291  [8]
 LDCM0413  CL25 PaTu 8988t C209(0.77)  LDD1292  [8]
 LDCM0414  CL26 PaTu 8988t C209(1.00)  LDD1293  [8]
 LDCM0415  CL27 PaTu 8988t C209(0.91)  LDD1294  [8]
 LDCM0416  CL28 PaTu 8988t C209(1.14)  LDD1295  [8]
 LDCM0417  CL29 PaTu 8988t C209(1.30)  LDD1296  [8]
 LDCM0418  CL3 HEK-293T C209(0.86)  LDD1016  [8]
 LDCM0419  CL30 PaTu 8988t C209(0.96)  LDD1298  [8]
 LDCM0420  CL31 HEK-293T C209(0.76); C449(0.79)  LDD1018  [8]
 LDCM0421  CL32 HEK-293T C209(0.70); C449(0.97)  LDD1019  [8]
 LDCM0422  CL33 HEK-293T C209(0.59); C449(0.69)  LDD1020  [8]
 LDCM0423  CL34 HEK-293T C209(0.97); C449(0.90)  LDD1021  [8]
 LDCM0424  CL35 HEK-293T C209(0.97); C449(0.80)  LDD1022  [8]
 LDCM0425  CL36 HEK-293T C209(0.98); C449(0.93)  LDD1023  [8]
 LDCM0426  CL37 HEK-293T C209(0.91); C449(0.84)  LDD1024  [8]
 LDCM0428  CL39 HEK-293T C209(1.01); C449(0.98)  LDD1026  [8]
 LDCM0429  CL4 HEK-293T C209(0.95)  LDD1027  [8]
 LDCM0430  CL40 HEK-293T C209(0.94); C449(0.93)  LDD1028  [8]
 LDCM0431  CL41 HEK-293T C209(1.06); C449(1.06)  LDD1029  [8]
 LDCM0432  CL42 HEK-293T C209(1.00); C449(1.09)  LDD1030  [8]
 LDCM0433  CL43 HEK-293T C209(1.06); C449(1.05)  LDD1031  [8]
 LDCM0434  CL44 HEK-293T C209(0.86); C449(0.87)  LDD1032  [8]
 LDCM0435  CL45 HEK-293T C209(0.99); C449(0.85)  LDD1033  [8]
 LDCM0436  CL46 HEK-293T C209(0.88)  LDD1034  [8]
 LDCM0437  CL47 HEK-293T C209(1.01)  LDD1035  [8]
 LDCM0438  CL48 HEK-293T C209(0.90)  LDD1036  [8]
 LDCM0439  CL49 HEK-293T C209(0.82)  LDD1037  [8]
 LDCM0440  CL5 HEK-293T C209(1.11)  LDD1038  [8]
 LDCM0441  CL50 HEK-293T C209(0.93)  LDD1039  [8]
 LDCM0442  CL51 HEK-293T C209(0.66)  LDD1040  [8]
 LDCM0443  CL52 HEK-293T C209(0.78)  LDD1041  [8]
 LDCM0444  CL53 HEK-293T C209(0.72)  LDD1042  [8]
 LDCM0445  CL54 HEK-293T C209(0.80)  LDD1043  [8]
 LDCM0446  CL55 HEK-293T C209(0.88)  LDD1044  [8]
 LDCM0447  CL56 HEK-293T C209(0.77)  LDD1045  [8]
 LDCM0448  CL57 HEK-293T C209(0.63)  LDD1046  [8]
 LDCM0449  CL58 HEK-293T C209(0.88)  LDD1047  [8]
 LDCM0450  CL59 HEK-293T C209(0.89)  LDD1048  [8]
 LDCM0451  CL6 HEK-293T C209(1.01)  LDD1049  [8]
 LDCM0452  CL60 HEK-293T C209(0.70)  LDD1050  [8]
 LDCM0453  CL61 PaTu 8988t C209(0.86)  LDD1332  [8]
 LDCM0454  CL62 PaTu 8988t C209(0.86)  LDD1333  [8]
 LDCM0455  CL63 PaTu 8988t C209(0.81)  LDD1334  [8]
 LDCM0456  CL64 PaTu 8988t C209(0.78)  LDD1335  [8]
 LDCM0457  CL65 PaTu 8988t C209(0.65)  LDD1336  [8]
 LDCM0458  CL66 PaTu 8988t C209(0.82)  LDD1337  [8]
 LDCM0459  CL67 PaTu 8988t C209(0.91)  LDD1338  [8]
 LDCM0460  CL68 PaTu 8988t C209(0.85)  LDD1339  [8]
 LDCM0461  CL69 PaTu 8988t C209(0.94)  LDD1340  [8]
 LDCM0462  CL7 HEK-293T C209(1.28)  LDD1060  [8]
 LDCM0463  CL70 PaTu 8988t C209(0.89)  LDD1342  [8]
 LDCM0464  CL71 PaTu 8988t C209(0.96)  LDD1343  [8]
 LDCM0465  CL72 PaTu 8988t C209(1.07)  LDD1344  [8]
 LDCM0466  CL73 PaTu 8988t C209(0.79)  LDD1345  [8]
 LDCM0467  CL74 PaTu 8988t C209(0.80)  LDD1346  [8]
 LDCM0469  CL76 PaTu 8988t C209(0.82)  LDD1348  [8]
 LDCM0470  CL77 PaTu 8988t C209(0.80)  LDD1349  [8]
 LDCM0471  CL78 PaTu 8988t C209(0.74)  LDD1350  [8]
 LDCM0472  CL79 PaTu 8988t C209(0.86)  LDD1351  [8]
 LDCM0473  CL8 PaTu 8988t C209(0.70)  LDD1352  [8]
 LDCM0474  CL80 PaTu 8988t C209(0.77)  LDD1353  [8]
 LDCM0475  CL81 PaTu 8988t C209(0.90)  LDD1354  [8]
 LDCM0476  CL82 PaTu 8988t C209(0.91)  LDD1355  [8]
 LDCM0477  CL83 PaTu 8988t C209(0.81)  LDD1356  [8]
 LDCM0478  CL84 PaTu 8988t C209(0.87)  LDD1357  [8]
 LDCM0479  CL85 PaTu 8988t C209(0.79)  LDD1358  [8]
 LDCM0480  CL86 PaTu 8988t C209(0.77)  LDD1359  [8]
 LDCM0481  CL87 PaTu 8988t C209(0.76)  LDD1360  [8]
 LDCM0482  CL88 PaTu 8988t C209(0.78)  LDD1361  [8]
 LDCM0483  CL89 PaTu 8988t C209(0.76)  LDD1362  [8]
 LDCM0484  CL9 PaTu 8988t C209(0.96)  LDD1363  [8]
 LDCM0485  CL90 PaTu 8988t C209(0.64)  LDD1364  [8]
 LDCM0486  CL91 HEK-293T C209(0.85)  LDD1084  [8]
 LDCM0487  CL92 HEK-293T C209(0.73)  LDD1085  [8]
 LDCM0488  CL93 HEK-293T C209(0.78)  LDD1086  [8]
 LDCM0489  CL94 HEK-293T C209(0.82)  LDD1087  [8]
 LDCM0490  CL95 HEK-293T C209(0.63)  LDD1088  [8]
 LDCM0491  CL96 HEK-293T C209(0.99)  LDD1089  [8]
 LDCM0492  CL97 HEK-293T C209(0.69)  LDD1090  [8]
 LDCM0493  CL98 HEK-293T C209(0.78)  LDD1091  [8]
 LDCM0494  CL99 HEK-293T C209(1.00)  LDD1092  [8]
 LDCM0027  Dopamine HEK-293T 4.58  LDD0179  [2]
 LDCM0495  E2913 HEK-293T C8(1.06)  LDD1698  [9]
 LDCM0031  Epigallocatechin gallate HEK-293T 8.54  LDD0183  [2]
 LDCM0625  F8 Ramos C449(1.11)  LDD2187  [10]
 LDCM0573  Fragment11 Ramos C449(0.35)  LDD2190  [10]
 LDCM0574  Fragment12 Ramos C449(0.78)  LDD2191  [10]
 LDCM0575  Fragment13 Ramos C449(0.69)  LDD2192  [10]
 LDCM0576  Fragment14 Ramos C449(1.40)  LDD2193  [10]
 LDCM0579  Fragment20 Ramos C449(0.82)  LDD2194  [10]
 LDCM0580  Fragment21 Ramos C449(0.97)  LDD2195  [10]
 LDCM0582  Fragment23 Ramos C449(1.05)  LDD2196  [10]
 LDCM0578  Fragment27 Ramos C449(0.67)  LDD2197  [10]
 LDCM0586  Fragment28 Ramos C449(0.86)  LDD2198  [10]
 LDCM0588  Fragment30 Ramos C449(1.39)  LDD2199  [10]
 LDCM0589  Fragment31 Ramos C449(0.76)  LDD2200  [10]
 LDCM0590  Fragment32 Ramos C449(0.99)  LDD2201  [10]
 LDCM0468  Fragment33 PaTu 8988t C209(1.05)  LDD1347  [8]
 LDCM0596  Fragment38 Ramos C449(0.77)  LDD2203  [10]
 LDCM0566  Fragment4 Ramos C449(1.14)  LDD2184  [10]
 LDCM0427  Fragment51 HEK-293T C209(0.99); C449(0.94)  LDD1025  [8]
 LDCM0610  Fragment52 Ramos C449(1.23)  LDD2204  [10]
 LDCM0614  Fragment56 Ramos C449(1.19)  LDD2205  [10]
 LDCM0571  Fragment9 Ramos C449(0.76)  LDD2188  [10]
 LDCM0022  KB02 A673 C67(2.35)  LDD2261  [1]
 LDCM0023  KB03 Ramos C449(0.97)  LDD2183  [10]
 LDCM0024  KB05 SK-N-MC C67(2.59)  LDD3434  [1]
 LDCM0032  Oleacein HEK-293T 5.93  LDD0184  [2]
 LDCM0029  Quercetin HEK-293T 6.35  LDD0181  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable ATP-dependent RNA helicase DDX6 (DDX6) DEAD box helicase family P26196
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Proteasome subunit alpha type-3 (PSMA3) Peptidase T1A family P25788
Testis-specific serine/threonine-protein kinase 3 (TSSK3) CAMK Ser/Thr protein kinase family Q96PN8
Exosome complex component RRP43 (EXOSC8) RNase PH family Q96B26
Kinesin-like protein KIF9 (KIF9) Kinesin family Q9HAQ2
Ret finger protein-like 3 (RFPL3) . O75679
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) Cytochrome c oxidase subunit 5B family P10606
Nuclear RNA export factor 1 (NXF1) NXF family Q9UBU9
Transcription factor
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C8 (HOXC8) Antp homeobox family P31273
Transcription factor AP-2-delta (TFAP2D) AP-2 family Q7Z6R9
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
Paired box protein Pax-9 (PAX9) . P55771
Other
Click To Hide/Show 18 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Atos homolog protein B (ATOSB) ATOS family Q7L5A3
EF-hand calcium-binding domain-containing protein 4B (CRACR2A) EFCAB4 family Q9BSW2
Homer protein homolog 3 (HOMER3) Homer family Q9NSC5
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31) PRP31 family Q8WWY3
AFG2-interacting ribosome maturation factor (AIRIM) . Q9NX04
Armadillo repeat-containing protein 7 (ARMC7) . Q9H6L4
BTB/POZ domain-containing protein KCTD9 (KCTD9) . Q7L273
EF-hand domain-containing protein 1 (EFHC1) . Q5JVL4
Fibroblast growth factor receptor substrate 3 (FRS3) . O43559
Four and a half LIM domains protein 2 (FHL2) . Q14192
Four and a half LIM domains protein 3 (FHL3) . Q13643
Golgin subfamily A member 1 (GOLGA1) . Q92805
Heat shock factor 2-binding protein (HSF2BP) . O75031
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) . P52597
PDZ and LIM domain protein 7 (PDLIM7) . Q9NR12
Rho guanine nucleotide exchange factor 5 (ARHGEF5) . Q12774
TBC1 domain family member 22B (TBC1D22B) . Q9NU19

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
6 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
7 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
8 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578