Details of the Target

General Information of Target

Target ID LDTP01637
Target Name Pericentrin (PCNT)
Gene Name PCNT
Gene ID 5116
Synonyms
KIAA0402; PCNT2; Pericentrin; Kendrin; Pericentrin-B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEVEQEQRRRKVEAGRTKLAHFRQRKTKGDSSHSEKKTAKRKGSAVDASVQEESPVTKED
SALCGGGDICKSTSCDDTPDGAGGAFAAQPEDCDGEKREDLEQLQQKQVNDHPPEQCGMF
TVSDHPPEQHGMFTVGDHPPEQRGMFTVSDHPPEQHGMFTVSDHPPEQRGMFTISDHQPE
QRGMFTVSDHTPEQRGIFTISDHPAEQRGMFTKECEQECELAITDLESGREDEAGLHQSQ
AVHGLELEALRLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQ
HELELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLEN
LRKELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLR
EDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKAQSQEEIRRLWSQLDSARTS
RQELSELHEQLLARTSRVEDLEQLKQREKTQHESELEQLRIYFEKKLRDAEKTYQEDLTL
LQQRLQGAREDALLDSVEVGLSCVGLEEKPEKGRKDHVDELEPERHKESLPRFQAELEES
HRHQLEALESPLCIQHEGHVSDRCCVETSALGHEWRLEPSEGHSQELPWVHLQGVQDGDL
EADTERAARVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVK
HNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAES
EKQTIINKFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHCSQCG
REPPTAQDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARE
LQLLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQTKHAADLGAL
ETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQTILTQELEKLK
RKHEGELQSVRDHLRTEVSTELAGTVAHELQGVHQGEFGSEKKTALHEKEETLRLQSAQA
QPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEECRSELEVLQQRRERENREGANL
LSMLKADVNLSHSERGALQDALRRLLGLFGETLRAAVTLRSRIGERVGLCLDDAGAGLAL
STAPALEETWSDVALPELDRTLSECAEMSSVAEISSHMRESFLMSPESVRECEQPIRRVF
QSLSLAVDGLMEMALDSSRQLEEARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEES
AAKAELALELHKTQGTLEGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQA
ALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILE
SELEEQLSQHRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQ
RLEGQLRQAAKPQPWGPRDSQQAPLDGEVELLQQKLREKLDEFNELAIQKESADRQVLMQ
EEEIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTL
DAGRCPEPPSGSPPEGPEIQLEVTQRALLRRESEVLDLKEQLEKMKGDLESKNEEILHLN
LKLDMQNSQTAVSLRELEEENTSLKVIYTRSSEIEELKATIENLQENQKRLQKEKAEEIE
QLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEAKE
ALSRLLADQERRHSQALEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQEFE
AALKAKEATIAERNLEIDALNQRKAAHSAELEAVLLALARIRRALEQQPLAAGAAPPELQ
WLRAQCARLSRQLQVLHQRFLRCQVELDRRQARRATAHTRVPGAHPQPRMDGGAKAQVTG
DVEASHDAALEPVVPDPQGDLQPVLVTLKDAPLCKQEGVMSVLTVCQRQLQSELLLVKNE
MRLSLEDGGKGKEKVLEDCQLPKVDLVAQVKQLQEKLNRLLYSMTFQNVDAADTKSLWPM
ASAHLLESSWSDDSCDGEEPDISPHIDTCDANTATGGVTDVIKNQAIDACDANTTPGGVT
DVIKNWDSLIPDEMPDSPIQEKSECQDMSLSSPTSVLGGSRHQSHTAEAGPRKSPVGMLD
LSSWSSPEVLRKDWTLEPWPSLPVTPHSGALSLCSADTSLGDRADTSLPQTQGPGLLCSP
GVSAAALALQWAESPPADDHHVQRTAVEKDVEDFITTSFDSQETLSSPPPGLEGKADRSE
KSDGSGFGARLSPGSGGPEAQTAGPVTPASISGRFQPLPEAMKEKEVRPKHVKALLQMVR
DESHQILALSEGLAPPSGEPHPPRKEDEIQDISLHGGKTQEVPTACPDWRGDLLQVVQEA
FEKEQEMQGVELQPRLSGSDLGGHSSLLERLEKIIREQGDLQEKSLEHLRLPDRSSLLSE
IQALRAQLRMTHLQNQEKLQHLRTALTSAEARGSQQEHQLRRQVELLAYKVEQEKCIAGD
LQKTLSEEQEKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSM
LSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQ
SSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSEA
LRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQ
QLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSHP
RLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQQTVRD
LESKDEVPGSRLHLGSARRAAGSDADHLREQQRELEAMRQRLLSAARLLTSFTSQAVDRT
VNDWTSSNEKAVMSLLHTLEELKSDLSRPTSSQKKMAAELQFQFVDVLLKDNVSLTKALS
TVTQEKLELSRAVSKLEKLLKHHLQKGCSPSRSERSAWKPDETAPQSSLRRPDPGRLPPA
ASEEAHTSNVKMEKLYLHYLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVF
PSKAERKITSRPFTRFRTAVRVVIAILRLRFLVKKWQEVDRKGALAQGKAPRPGPRARQP
QSPPRTRESPPTRDVPSGHTRDPARGRRLAAAASPHSGGRATPSPNSRLERSLTASQDPE
HSLTEYIHHLEVIQQRLGGVLPDSTSKKSCHPMIKQ
Target Bioclass
Other
Subcellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Function
Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome.
Uniprot ID
O95613
Ensemble ID
ENST00000359568.10
HGNC ID
HGNC:16068

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2780 SNV: p.R3110K DBIA    Probe Info 
CMK SNV: p.L2635F .
COLO320 SNV: p.R2959G DBIA    Probe Info 
DOTC24510 SNV: p.D2262N DBIA    Probe Info 
DU145 SNV: p.M2174I DBIA    Probe Info 
HCC1954 SNV: p.G2273R DBIA    Probe Info 
HDQP1 SNV: p.A293G DBIA    Probe Info 
HSC4 SNV: p.S2283F DBIA    Probe Info 
HT Insertion: p.N3286KfsTer50 DBIA    Probe Info 
HT1197 SNV: p.E2856Q DBIA    Probe Info 
IGROV1 Deletion: p.G2137VfsTer2 .
Ishikawa (Heraklio) 02 ER SNV: p.A1203T DBIA    Probe Info 
JURKAT SNV: p.E1061K; p.A3142V Compound 10    Probe Info 
JURLMK1 SNV: p.G2949S .
KURAMOCHI SNV: p.E1118K .
KYSE510 SNV: p.R2908M DBIA    Probe Info 
LS180 SNV: p.R1031W; p.E2688D DBIA    Probe Info 
MCC13 SNV: p.P1995L; p.E2507K DBIA    Probe Info 
MELHO SNV: p.D3262A DBIA    Probe Info 
MFE296 SNV: p.L527S; p.S2894G DBIA    Probe Info 
MFE319 SNV: p.K2591R .
NCIH1048 SNV: p.H3082Y .
NCIH1650 SNV: p.E3094Q DBIA    Probe Info 
RKO SNV: p.T1045A .
SKMEL2 SNV: p.F1859L DBIA    Probe Info 
SNGM SNV: p.G2210V; p.R2529C DBIA    Probe Info 
SNU5 SNV: p.N2717S DBIA    Probe Info 
SUDHL6 SNV: p.V1187M .
TOV21G SNV: p.Q1932H; p.H2787N .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [2]
STPyne
 Probe Info  		K1472(0.65); K2932(5.00); K3086(10.00); K788(1.12)  LDD0277  [3]
DA-P3
 Probe Info  		14.42  LDD0179  [4]
AHL-Pu-1
 Probe Info  		C1315(3.10); C2628(2.16)  LDD0168  [5]
DBIA
 Probe Info  		C75(1.18); C93(1.18); C64(1.01); C70(1.01)  LDD0078  [6]
IA-alkyne
 Probe Info  		C974(0.00); C860(0.00); C321(0.00); C2059(0.00)  LDD0165  [7]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [8]
NAIA_4
 Probe Info  		N.A.  LDD2226  [9]
WYneN
 Probe Info  		N.A.  LDD0021  [10]
Compound 10
 Probe Info  		N.A.  LDD2216  [11]
IPM
 Probe Info  		N.A.  LDD0005  [10]
TFBX
 Probe Info  		C1225(0.00); C321(0.00); C430(0.00); C1943(0.00)  LDD0148  [12]
AOyne
 Probe Info  		13.60  LDD0443  [13]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C1315(3.10); C2628(2.16)  LDD0168  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C2150(2.41)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C1252(1.31)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C2614(0.97)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C2446(0.83); C64(1.01); C70(1.01)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C2446(1.14); C64(0.98); C70(0.98)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C2446(0.92); C64(1.01); C70(1.01)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C2446(1.14); C64(1.40); C70(1.40)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C2446(0.96); C64(1.31); C70(1.31)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C2446(1.15); C64(1.33); C70(1.33)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C2446(1.16); C64(1.12); C70(1.12)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C2446(0.93); C64(1.03); C70(1.03)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C2446(0.97); C64(1.01); C70(1.01)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C2446(0.79); C64(1.04); C70(1.04)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C2614(0.82)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C2446(1.16); C64(1.12); C70(1.12)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C2446(0.90); C64(1.01); C70(1.01)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C2446(0.86); C64(0.86); C70(0.86)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C2614(1.06)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C2614(1.11)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C2614(1.08)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C2614(1.22)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C2614(0.90)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C2614(1.02)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C2614(1.28)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C2614(1.37)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C2614(1.03)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C2614(1.13)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C2614(1.21)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C2614(0.89)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C2614(1.02)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C2614(1.04)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C2614(1.15)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C2614(1.19)  LDD0562  [6]
 LDCM0246  AC128 HEK-293T C1252(0.86); C215(0.93); C2446(1.18)  LDD0844  [6]
 LDCM0247  AC129 HEK-293T C1252(1.04); C215(0.81); C2446(1.32)  LDD0845  [6]
 LDCM0249  AC130 HEK-293T C1252(0.89); C215(0.93); C2446(1.27)  LDD0847  [6]
 LDCM0250  AC131 HEK-293T C1252(0.80); C215(0.87); C2446(0.95)  LDD0848  [6]
 LDCM0251  AC132 HEK-293T C1252(1.05); C215(0.87); C2446(1.61)  LDD0849  [6]
 LDCM0252  AC133 HEK-293T C1252(1.06); C215(0.79); C2446(0.96)  LDD0850  [6]
 LDCM0253  AC134 HEK-293T C1252(0.83); C215(0.69); C2446(1.06)  LDD0851  [6]
 LDCM0254  AC135 HEK-293T C1252(1.01); C215(1.03); C2446(1.05)  LDD0852  [6]
 LDCM0255  AC136 HEK-293T C1252(0.90); C215(1.00); C2446(1.28)  LDD0853  [6]
 LDCM0256  AC137 HEK-293T C1252(1.07); C215(0.77); C2446(1.35)  LDD0854  [6]
 LDCM0257  AC138 HEK-293T C1252(0.72); C215(0.75); C2446(1.21)  LDD0855  [6]
 LDCM0258  AC139 HEK-293T C1252(0.89); C215(0.88); C2446(1.24)  LDD0856  [6]
 LDCM0259  AC14 HCT 116 C2614(0.78)  LDD0576  [6]
 LDCM0260  AC140 HEK-293T C1252(0.88); C215(0.83); C2446(1.20)  LDD0858  [6]
 LDCM0261  AC141 HEK-293T C1252(1.02); C215(0.70); C2446(1.26)  LDD0859  [6]
 LDCM0262  AC142 HEK-293T C1252(0.82); C215(0.78); C2446(1.33)  LDD0860  [6]
 LDCM0263  AC143 HEK-293T C1943(1.02); C1252(0.84); C2446(0.66); C2614(0.73)  LDD0861  [6]
 LDCM0264  AC144 HEK-293T C1943(0.97); C1252(1.00); C2446(0.95); C2614(0.92)  LDD0862  [6]
 LDCM0265  AC145 HEK-293T C1943(1.05); C1252(1.17); C2446(0.94); C2614(0.87)  LDD0863  [6]
 LDCM0266  AC146 HEK-293T C1943(0.84); C1252(1.11); C2446(0.91); C2614(1.09)  LDD0864  [6]
 LDCM0267  AC147 HEK-293T C1943(0.87); C1252(0.83); C2446(0.86); C2614(0.86)  LDD0865  [6]
 LDCM0268  AC148 HEK-293T C1943(0.84); C1252(0.98); C2446(0.72); C2614(0.86)  LDD0866  [6]
 LDCM0269  AC149 HEK-293T C1943(0.93); C1252(0.97); C2446(0.94); C2614(0.83)  LDD0867  [6]
 LDCM0270  AC15 HCT 116 C2614(0.73)  LDD0587  [6]
 LDCM0271  AC150 HEK-293T C1943(0.77); C1252(0.94); C2446(0.72); C2614(0.89)  LDD0869  [6]
 LDCM0272  AC151 HEK-293T C1943(0.88); C1252(1.05); C2446(0.97); C2614(0.75)  LDD0870  [6]
 LDCM0273  AC152 HEK-293T C1943(0.90); C1252(0.93); C2446(0.86); C2614(0.97)  LDD0871  [6]
 LDCM0274  AC153 HEK-293T C1943(0.58); C1252(0.89); C2446(1.07); C2614(0.91)  LDD0872  [6]
 LDCM0621  AC154 HEK-293T C1943(0.92); C1252(1.05); C2446(0.79); C2614(1.05)  LDD2162  [6]
 LDCM0622  AC155 HEK-293T C1943(0.89); C1252(0.99); C2446(1.07); C2614(0.97)  LDD2163  [6]
 LDCM0623  AC156 HEK-293T C1943(0.69); C1252(0.92); C2446(1.00); C2614(0.99)  LDD2164  [6]
 LDCM0624  AC157 HEK-293T C1943(0.81); C1252(0.79); C2446(0.72); C2614(1.03)  LDD2165  [6]
 LDCM0276  AC17 HCT 116 C2446(1.04); C2614(1.11)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C2614(0.65); C2446(0.71)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C2614(0.76); C2446(1.06)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C1252(1.45)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C2614(0.77); C2446(0.99)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C2614(0.66); C2446(1.00)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C2614(0.93); C2446(1.51)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C2614(0.80); C2446(1.00)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C2614(0.91); C2446(1.23)  LDD0601  [6]
 LDCM0285  AC25 HEK-293T C1943(0.78); C1252(0.70); C2150(0.78); C2446(0.85)  LDD0883  [6]
 LDCM0286  AC26 HEK-293T C1943(1.06); C1252(0.77); C2150(0.85); C2446(0.91)  LDD0884  [6]
 LDCM0287  AC27 HEK-293T C1943(1.21); C1252(0.92); C2150(0.92); C2446(0.96)  LDD0885  [6]
 LDCM0288  AC28 HEK-293T C1943(1.28); C1252(1.24); C2150(0.80); C2446(1.23)  LDD0886  [6]
 LDCM0289  AC29 HEK-293T C1943(1.09); C1252(0.93); C2150(0.86); C2446(0.88)  LDD0887  [6]
 LDCM0290  AC3 HCT 116 C1252(2.07)  LDD0607  [6]
 LDCM0291  AC30 HEK-293T C1943(1.25); C1252(0.92); C2150(0.80); C2446(0.97)  LDD0889  [6]
 LDCM0292  AC31 HEK-293T C1943(1.07); C1252(1.38); C2150(0.93); C2446(1.16)  LDD0890  [6]
 LDCM0293  AC32 HEK-293T C1943(0.98); C1252(0.79); C2150(0.79); C2446(0.90)  LDD0891  [6]
 LDCM0294  AC33 HEK-293T C1943(1.00); C1252(0.79); C2150(0.77); C2446(0.89)  LDD0892  [6]
 LDCM0295  AC34 HEK-293T C1943(0.96); C1252(0.80); C2150(0.82); C2446(0.95)  LDD0893  [6]
 LDCM0296  AC35 HCT 116 C1252(0.58); C2446(0.85)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C1252(0.73); C2446(0.94)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C1252(0.59); C2446(0.93)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C2446(1.02); C1252(1.10)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C1252(0.85); C2446(1.06)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C1252(1.65)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C1252(0.57); C2446(0.99)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C1252(0.81); C2446(1.03)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C2446(1.11); C1252(1.56)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C1252(1.08); C2446(1.15)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C2446(0.84); C1252(0.94)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C1252(0.60); C2446(1.05)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C1252(2.91)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C1252(1.69)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C1252(1.40)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C1252(1.25)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C1252(1.65)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C1252(1.56)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C1252(1.39)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C1252(1.51)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C1252(1.78)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C1252(1.38)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C1252(1.74)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C1252(1.28)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C1252(1.99)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C1252(1.67)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C1252(2.47)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C2614(0.84)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C1252(3.35)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C1252(3.54)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C1252(3.58)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C1252(6.61)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C1252(2.43)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C1252(1.78)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C1252(3.42)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C1252(2.97)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C64(0.73); C70(0.73); C1252(1.17)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C64(0.93); C70(0.93); C1252(1.12)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C2614(0.76)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C64(0.81); C70(0.81); C1252(1.08)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C64(0.65); C70(0.65); C1252(0.98)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C1252(0.95); C64(0.98); C70(0.98)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C64(1.03); C70(1.03); C1252(1.20)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C64(1.05); C70(1.05); C1252(1.06)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C1252(1.01); C64(1.13); C70(1.13)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C64(1.11); C70(1.11); C1252(1.11)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C64(0.89); C70(0.89); C1252(1.14)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C64(0.93); C70(0.93); C1252(1.02)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C64(0.78); C70(0.78); C1252(0.97)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C2614(0.71)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C1252(1.03); C64(1.21); C70(1.21)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C64(0.82); C70(0.82); C1252(1.03)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C64(0.84); C70(0.84); C1252(1.01)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C64(1.52); C70(1.52)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C64(1.27); C70(1.27)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C64(1.02); C70(1.02)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C64(1.24); C70(1.24)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C64(1.23); C70(1.23)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C64(1.42); C70(1.42)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C64(1.77); C70(1.77)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C64(1.30); C70(1.30)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C64(1.31); C70(1.31)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C64(1.40); C70(1.40)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C64(1.22); C70(1.22)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C64(1.13); C70(1.13)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C64(1.23); C70(1.23)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C64(1.71); C70(1.71)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C64(1.70); C70(1.70)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C2446(1.23); C64(1.76); C70(1.76)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C2446(0.78); C64(0.94); C70(0.94)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C2614(0.96)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C2614(0.66)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C2614(0.79)  LDD0592  [6]
 LDCM0020  ARS-1620 HCC44 C75(1.18); C93(1.18); C64(1.01); C70(1.01)  LDD0078  [6]
 LDCM0367  CL1 HCT 116 C2614(1.18); C1252(1.36)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C1252(0.87); C2614(1.16)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C1252(1.29)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C2614(0.77)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C2614(0.92)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C2614(0.91)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C2614(0.86)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C2614(0.91); C2446(1.08)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C2614(0.75); C2446(1.04)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C2614(0.86); C2446(1.15)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C2446(1.24); C2614(1.35)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C2614(0.70); C2446(0.96)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C2614(0.72); C1252(0.76)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C2614(1.05); C2446(1.29)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C2614(1.00); C2446(1.18)  LDD0698  [6]
 LDCM0382  CL112 HEK-293T C1943(1.49); C1252(1.01); C2150(0.87); C2446(1.00)  LDD0980  [6]
 LDCM0383  CL113 HEK-293T C1943(1.05); C1252(0.90); C2150(0.88); C2446(0.96)  LDD0981  [6]
 LDCM0384  CL114 HEK-293T C1943(1.67); C1252(0.82); C2150(0.85); C2446(0.86)  LDD0982  [6]
 LDCM0385  CL115 HEK-293T C1943(1.28); C1252(0.84); C2150(0.71); C2446(1.00)  LDD0983  [6]
 LDCM0386  CL116 HEK-293T C1943(1.47); C1252(0.76); C2150(0.77); C2446(0.94)  LDD0984  [6]
 LDCM0387  CL117 HCT 116 C1252(0.87); C2446(1.54)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C1252(0.89); C2446(1.07)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C1252(0.96); C2446(1.02)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C1252(0.94); C2614(1.44)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C1252(0.93); C2446(1.18)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C1252(1.06)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C1252(1.61)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C1252(1.54)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C1252(1.39)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C1252(1.11)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C1252(1.87)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C1252(1.65)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C1252(1.99)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C1252(1.04); C2614(1.36)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C1252(0.93); C2614(1.01)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C1252(0.79); C2614(1.20)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C1252(1.60)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C1252(0.65); C2446(0.92)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C2446(0.89); C1252(1.00)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C1252(1.00); C2446(1.04)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C1252(1.16); C2614(1.22)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C1252(1.19); C2446(1.21)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C1252(0.87); C2446(0.95)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C2446(1.06); C1252(1.23)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C1252(0.71); C2446(0.74)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C2446(1.06); C1252(1.83)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C1252(1.25); C2446(0.73)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C1252(0.96); C2446(0.95)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C1252(1.27); C2446(0.96)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C1252(1.01); C2446(0.52)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C1252(1.70); C2446(1.15)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C1252(0.99); C2614(1.11)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C1252(1.49); C2446(0.88)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C2446(0.82)  LDD0737  [6]
 LDCM0421  CL32 HEK-293T C1943(2.31); C1252(0.24); C2446(0.24); C2628(0.95)  LDD1019  [6]
 LDCM0422  CL33 HEK-293T C1943(2.79); C1252(0.44); C2446(0.44); C2628(0.75)  LDD1020  [6]
 LDCM0423  CL34 HEK-293T C1943(1.50); C1252(0.34); C2446(0.34); C2628(0.86)  LDD1021  [6]
 LDCM0424  CL35 HEK-293T C1943(1.63); C1252(0.28); C2446(0.28); C2628(0.91)  LDD1022  [6]
 LDCM0425  CL36 HEK-293T C1943(1.80); C1252(0.32); C2446(0.32); C2628(0.93)  LDD1023  [6]
 LDCM0426  CL37 HEK-293T C1943(0.93); C1252(0.52); C2446(0.52); C2628(1.17)  LDD1024  [6]
 LDCM0428  CL39 HEK-293T C1943(3.07); C1252(0.47); C2446(0.47); C2628(0.63)  LDD1026  [6]
 LDCM0429  CL4 HCT 116 C1252(1.04); C2614(0.83)  LDD0746  [6]
 LDCM0430  CL40 HEK-293T C1943(1.93); C1252(0.42); C2446(0.42); C2628(0.85)  LDD1028  [6]
 LDCM0431  CL41 HEK-293T C1943(2.64); C1252(0.33); C2446(0.33); C2628(0.68)  LDD1029  [6]
 LDCM0432  CL42 HEK-293T C1943(2.89); C1252(0.33); C2446(0.33); C2628(0.60)  LDD1030  [6]
 LDCM0433  CL43 HEK-293T C1943(2.25); C1252(0.33); C2446(0.33); C2628(0.74)  LDD1031  [6]
 LDCM0434  CL44 HEK-293T C1943(1.38); C1252(0.32); C2446(0.32); C2628(0.86)  LDD1032  [6]
 LDCM0435  CL45 HEK-293T C1943(4.04); C1252(0.32); C2446(0.32); C2628(0.81)  LDD1033  [6]
 LDCM0436  CL46 HCT 116 C2446(1.20); C2614(1.13)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C2446(1.16); C2614(0.75)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C2446(1.17); C2614(1.15)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C2446(1.10); C2614(1.03)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C1252(1.11); C2614(0.97)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C2446(1.14); C2614(1.20)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C2446(1.29); C2614(0.91)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C2446(1.46); C2614(1.01)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C2446(1.31); C2614(0.78)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C2446(1.24); C2614(0.97)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C2446(0.98); C2614(1.13)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C2446(1.00); C2614(0.81)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C2446(1.24); C2614(0.75)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C2446(1.08); C2614(1.02)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C2446(1.01); C2614(0.92)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C1252(1.12); C2614(1.23)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C2446(1.49); C2614(0.94)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C1252(1.09); C2446(1.45)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C1252(1.63); C2446(1.32)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C1252(1.10); C2446(1.15)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C1252(1.30); C2446(1.35)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C1252(1.06); C2446(1.18)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C1252(1.30); C2446(1.15)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C1252(1.17); C2446(0.94)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C1252(1.59); C2446(1.20)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C1252(1.01); C2446(1.10)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C1252(1.24); C2614(1.52)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C1252(1.14); C2446(1.00)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C1252(1.02); C2446(1.11)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C1252(0.74); C2446(1.29)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C1252(1.19); C2446(1.21)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C1252(0.96); C2446(1.26)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C64(0.55); C70(0.55)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C64(0.48); C70(0.48)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C64(0.61); C70(0.61)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C64(0.66); C70(0.66)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C1252(1.21); C2614(1.03)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C64(0.69); C70(0.69)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C64(0.62); C70(0.62)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C64(0.42); C70(0.42)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C64(0.60); C70(0.60)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C64(0.70); C70(0.70)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C64(0.67); C70(0.67)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C64(0.47); C70(0.47)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C64(0.36); C70(0.36)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C64(0.52); C70(0.52)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C64(0.54); C70(0.54)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C1252(1.37); C2614(1.20)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C64(0.35); C70(0.35)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C1252(1.80)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C1252(1.02)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C1252(1.03)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C1252(1.01)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C1252(1.31)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C1252(1.34)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C1252(1.27)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C1252(1.37)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C1252(1.82)  LDD0811  [6]
 LDCM0198  Dimethyl Fumarate(DMF) T cell C2705(5.81)  LDD0513  [14]
 LDCM0027  Dopamine HEK-293T 14.42  LDD0179  [4]
 LDCM0495  E2913 HEK-293T C1252(0.94); C1943(0.97); C321(0.90); C2446(0.83)  LDD1698  [15]
 LDCM0031  Epigallocatechin gallate HEK-293T 11.98  LDD0183  [4]
 LDCM0468  Fragment33 HCT 116 C1252(0.92); C2446(1.12)  LDD0785  [6]
 LDCM0427  Fragment51 HEK-293T C1943(1.34); C1252(0.33); C2446(0.33); C2628(1.31)  LDD1025  [6]
 LDCM0022  KB02 HCT 116 C64(3.14); C70(3.14)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C64(1.95); C70(1.95)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C64(2.05); C70(2.05)  LDD0082  [6]
 LDCM0029  Quercetin HEK-293T 7.31  LDD0181  [4]
 LDCM0021  THZ1 HCT 116 C2614(0.82); C64(1.04); C70(1.04)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Pericentriolar material 1 protein (PCM1) PCM1 family Q15154
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Centrosomal protein of 68 kDa (CEP68) . Q76N32
Disrupted in schizophrenia 1 protein (DISC1) . Q9NRI5

References

1 Labeling Preferences of Diazirines with Protein Biomolecules. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20.
Mass spectrometry data entry: PXD025140
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
8 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
9 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
12 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
13 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
14 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402