Details of the Probe

General Information of Probe

Probe ID
LDPC0465
Probe Name
C232
Synonyms
Z4286591586
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 405.5
Lipid-water partition coefficient (xlogp) 3.4
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C21H19N5O2S
IUPAC Name
2-benzyl-N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=CN=C3N(C2=O)C=C(S3)CC4=CC=CC=C4
InChI
InChI=1S/C21H19N5O2S/c1-2-3-9-21(24-25-21)10-11-22-18(27)17-13-23-20-26(19(17)28)14-16(29-20)12-15-7-5-4-6-8-15/h1,4-8,13-14H,3,9-12H2,(H,22,27)
InChIKey
HTSBUIHAOFSTHM-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

133 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 61.82  LDD1905 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 48.50  LDD1905 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 51.98  LDD1905 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 37.27  LDD1905 
Abasic site processing protein HMCES (HMCES) LDTP10322 53.45  LDD1905 
Acid ceramidase (ASAH1) LDTP05905 61.39  LDD1905 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 86.22  LDD1905 
Adenosine kinase (ADK) LDTP04689 42.81  LDD1905 
Alpha-galactosidase A (GLA) LDTP02141 56.10  LDD1905 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 76.64  LDD1905 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 43.71  LDD1905 
Atlastin-2 (ATL2) LDTP09251 59.30  LDD1905 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 34.54  LDD1905 
ATP-binding cassette sub-family D member 3 (ABCD3) LDTP03424 40.50  LDD1905 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 44.94  LDD1905 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 33.82  LDD1905 
ATPase GET3 (GET3) LDTP00836 60.97  LDD1905 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 99.73  LDD1905 
Atypical kinase COQ8B, mitochondrial (COQ8B) LDTP10201 39.67  LDD1905 
Beta-glucuronidase (GUSB) LDTP02260 43.41  LDD1905 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 38.59  LDD1905 
Bifunctional epoxide hydrolase 2 (EPHX2) LDTP03692 45.57  LDD1905 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 33.82  LDD1905 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 62.68  LDD1905 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 51.63  LDD1905 
Cartilage-associated protein (CRTAP) LDTP01300 64.89  LDD1905 
Catechol O-methyltransferase (COMT) LDTP03145 76.11  LDD1905 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 81.01  LDD1905 
Ceramide synthase 2 (CERS2) LDTP10329 57.28  LDD1905 
Corrinoid adenosyltransferase MMAB (MMAB) LDTP10286 69.07  LDD1905 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1905 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 99.73  LDD1905 
Cytochrome b5 type B (CYB5B) LDTP00697 56.10  LDD1905 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 36.76  LDD1905 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 40.79  LDD1905 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 43.11  LDD1905 
Cytosolic purine 5'-nucleotidase (NT5C2) LDTP04327 35.26  LDD1905 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 42.22  LDD1905 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 34.06  LDD1905 
Delta(24)-sterol reductase (DHCR24) LDTP06375 39.40  LDD1905 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 34.06  LDD1905 
Dihydrofolate reductase (DHFR) LDTP01769 49.18  LDD1905 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 37.27  LDD1905 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 67.18  LDD1905 
Electron transfer flavoprotein subunit beta (ETFB) LDTP03849 60.97  LDD1905 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 33.36  LDD1905 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 52.35  LDD1905 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 41.07  LDD1905 
Epoxide hydrolase 1 (EPHX1) LDTP02175 37.01  LDD1905 
GTP-binding protein Rheb (RHEB) LDTP06371 37.79  LDD1905 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 50.56  LDD1905 
Heme A synthase COX15 (COX15) LDTP07931 99.73  LDD1905 
Heme oxygenase 1 (HMOX1) LDTP02359 86.22  LDD1905 
Heme oxygenase 2 (HMOX2) LDTP03540 72.50  LDD1905 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 40.22  LDD1905 
Holocytochrome c-type synthase (HCCS) LDTP04581 99.73  LDD1905 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 95.67  LDD1905 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 40.50  LDD1905 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 37.79  LDD1905 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 72.00  LDD1905 
Legumain (LGMN) LDTP10888 55.33  LDD1905 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 35.75  LDD1905 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 60.55  LDD1905 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 49.52  LDD1905 
Lysosomal alpha-glucosidase (GAA) LDTP02486 36.76  LDD1905 
Lysosomal protective protein (CTSA) LDTP02505 74.03  LDD1905 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 99.73  LDD1905 
Macrophage migration inhibitory factor (MIF) LDTP02713 69.55  LDD1905 
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) LDTP08512 36.76  LDD1905 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 44.02  LDD1905 
Minor histocompatibility antigen H13 (HM13) LDTP09396 61.82  LDD1905 
Mitochondrial tRNA-specific 2-thiouridylase 1 (TRMU) LDTP01284 37.79  LDD1905 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 99.73  LDD1905 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 35.02  LDD1905 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 96.34  LDD1905 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 64.45  LDD1905 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 41.93  LDD1905 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 55.33  LDD1905 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 96.34  LDD1905 
NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) LDTP00831 34.30  LDD1905 
NADH dehydrogenase iron-sulfur protein 3, mitochondrial (NDUFS3) LDTP01238 99.73  LDD1905 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 54.57  LDD1905 
Neurolysin, mitochondrial (NLN) LDTP11494 99.73  LDD1905 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 72.50  LDD1905 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 99.73  LDD1905 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 34.06  LDD1905 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 75.06  LDD1905 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 48.17  LDD1905 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 45.89  LDD1905 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 50.56  LDD1905 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 36.76  LDD1905 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 49.18  LDD1905 
Prolyl endopeptidase-like (PREPL) LDTP06849 35.75  LDD1905 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 33.82  LDD1905 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 43.11  LDD1905 
Prostaglandin reductase 3 (PTGR3) LDTP15422 60.13  LDD1905 
Protein arginine N-methyltransferase 9 (PRMT9) LDTP07525 38.32  LDD1905 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 39.95  LDD1905 
Protein O-GlcNAcase (OGA) LDTP00988 36.25  LDD1905 
Protein O-glucosyltransferase 1 (POGLUT1) LDTP09059 44.02  LDD1905 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 47.84  LDD1905 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 41.93  LDD1905 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 99.73  LDD1905 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 78.79  LDD1905 
Ras-related protein Rab-10 (RAB10) LDTP04895 35.02  LDD1905 
Ras-related protein Rab-11B (RAB11B) LDTP06501 47.84  LDD1905 
Ras-related protein Rab-1A (RAB1A) LDTP05006 41.36  LDD1905 
Ras-related protein Rab-1B (RAB1B) LDTP11733 35.75  LDD1905 
Ras-related protein Rab-24 (RAB24) LDTP10020 59.71  LDD1905 
Ras-related protein Rab-2A (RAB2A) LDTP04892 38.85  LDD1905 
Ras-related protein Rab-6A (RAB6A) LDTP03051 41.07  LDD1905 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 68.12  LDD1905 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 33.36  LDD1905 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 74.03  LDD1905 
Retinol dehydrogenase 13 (RDH13) LDTP09061 37.79  LDD1905 
Retinol dehydrogenase 14 (RDH14) LDTP12180 34.54  LDD1905 
Ribonuclease T2 (RNASET2) LDTP00316 33.36  LDD1905 
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) LDTP03592 38.85  LDD1905 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 35.75  LDD1905 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 34.54  LDD1905 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 34.06  LDD1905 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 99.73  LDD1905 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 42.52  LDD1905 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 89.88  LDD1905 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 50.21  LDD1905 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 40.22  LDD1905 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 40.50  LDD1905 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 68.12  LDD1905 
Ubiquitin carboxyl-terminal hydrolase 28 (USP28) LDTP10785 38.32  LDD1905 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 43.71  LDD1905 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 99.73  LDD1905 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 68.12  LDD1905 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (PDK3) LDTP06322 96.34  LDD1905 
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⏷ Show the Full List of 133 Enzyme
105 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 55.33  LDD1905 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 33.82  LDD1905 
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 35.02  LDD1905 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 47.50  LDD1905 
Amyloid-beta precursor protein (APP) LDTP02071 36.76  LDD1905 
ATP synthase subunit a (MT-ATP6) LDTP01804 99.73  LDD1905 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 72.50  LDD1905 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 37.27  LDD1905 
BRI3-binding protein (BRI3BP) LDTP15648 99.73  LDD1905 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 34.54  LDD1905 
Calnexin (CANX) LDTP03405 33.59  LDD1905 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 43.41  LDD1905 
Cystatin-B (CSTB) LDTP02009 37.27  LDD1905 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 52.35  LDD1905 
Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) LDTP03064 43.41  LDD1905 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 86.82  LDD1905 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 42.52  LDD1905 
Derlin-1 (DERL1) LDTP11245 47.50  LDD1905 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 56.49  LDD1905 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 35.75  LDD1905 
ER membrane protein complex subunit 4 (EMC4) LDTP06994 36.25  LDD1905 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.73  LDD1905 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 99.73  LDD1905 
Exportin-5 (XPO5) LDTP12142 56.49  LDD1905 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 33.82  LDD1905 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 54.19  LDD1905 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 43.71  LDD1905 
Importin subunit alpha-1 (KPNA2) LDTP04501 41.07  LDD1905 
Integral membrane protein 2B (ITM2B) LDTP13833 88.65  LDD1905 
Integral membrane protein 2C (ITM2C) LDTP12451 36.50  LDD1905 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 37.01  LDD1905 
Lysosome membrane protein 2 (SCARB2) LDTP06034 63.56  LDD1905 
Magnesium transporter protein 1 (MAGT1) LDTP11732 40.79  LDD1905 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 43.41  LDD1905 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 56.10  LDD1905 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 35.51  LDD1905 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 56.10  LDD1905 
Metaxin-1 (MTX1) LDTP05900 99.73  LDD1905 
Metaxin-2 (MTX2) LDTP01217 84.45  LDD1905 
MICOS complex subunit MIC26 (APOO) LDTP11250 47.50  LDD1905 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 41.93  LDD1905 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 35.02  LDD1905 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 49.52  LDD1905 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 36.76  LDD1905 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 58.49  LDD1905 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 99.73  LDD1905 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 53.08  LDD1905 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 62.68  LDD1905 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 68.59  LDD1905 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 57.68  LDD1905 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 37.27  LDD1905 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 47.84  LDD1905 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 96.34  LDD1905 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 37.27  LDD1905 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 33.59  LDD1905 
Mpv17-like protein 2 (MPV17L2) LDTP14952 44.02  LDD1905 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 47.84  LDD1905 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 71.01  LDD1905 
Peroxisomal biogenesis factor 3 (PEX3) LDTP04749 33.36  LDD1905 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 99.73  LDD1905 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 73.01  LDD1905 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 93.70  LDD1905 
PRA1 family protein 2 (PRAF2) LDTP01060 34.30  LDD1905 
Prosaposin (PSAP) LDTP02215 78.79  LDD1905 
Protein FAM8A1 (FAM8A1) LDTP16190 41.64  LDD1905 
Protein GPR108 (GPR108) LDTP12383 54.95  LDD1905 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 53.08  LDD1905 
Protein tweety homolog 3 (TTYH3) LDTP11615 56.10  LDD1905 
Protein wntless homolog (WLS) LDTP07156 75.06  LDD1905 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 99.73  LDD1905 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 41.93  LDD1905 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 34.78  LDD1905 
Secretory carrier-associated membrane protein 1 (SCAMP1) LDTP00546 34.54  LDD1905 
Sideroflexin-1 (SFXN1) LDTP12090 66.26  LDD1905 
Sideroflexin-4 (SFXN4) LDTP07531 39.12  LDD1905 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 41.93  LDD1905 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 63.56  LDD1905 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 93.05  LDD1905 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 99.73  LDD1905 
Solute carrier family 35 member F1 (SLC35F1) LDTP15000 36.00  LDD1905 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 39.67  LDD1905 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 36.76  LDD1905 
Surfeit locus protein 4 (SURF4) LDTP00592 99.73  LDD1905 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 56.49  LDD1905 
Syntaxin-5 (STX5) LDTP05780 41.93  LDD1905 
Tetraspanin-3 (TSPAN3) LDTP16813 99.73  LDD1905 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 88.03  LDD1905 
Translocator protein (TSPO) LDTP03546 38.05  LDD1905 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1905 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 59.71  LDD1905 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 33.59  LDD1905 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 34.30  LDD1905 
Transmembrane protein 126A (TMEM126A) LDTP15948 78.79  LDD1905 
Transmembrane protein 160 (TMEM160) LDTP20002 89.88  LDD1905 
Transmembrane protein 199 (TMEM199) LDTP08881 45.57  LDD1905 
Transmembrane protein 201 (TMEM201) LDTP07058 40.22  LDD1905 
Transmembrane protein 205 (TMEM205) LDTP07667 58.08  LDD1905 
Transmembrane protein 230 (TMEM230) LDTP10065 51.63  LDD1905 
Transmembrane protein 87A (TMEM87A) LDTP15481 55.72  LDD1905 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 47.18  LDD1905 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 58.08  LDD1905 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 69.55  LDD1905 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 48.84  LDD1905 
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) LDTP11281 35.75  LDD1905 
Wolframin (WFS1) LDTP01380 41.07  LDD1905 
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⏷ Show the Full List of 105 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Y-box-binding protein 1 (YBX1) LDTP05065 36.25  LDD1905 
Zinc finger protein 281 (ZNF281) LDTP13928 36.25  LDD1905 
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124 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
A-kinase anchor protein 8 (AKAP8) LDTP00880 34.30  LDD1905 
Alpha-internexin (INA) LDTP06527 42.81  LDD1905 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 33.36  LDD1905 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 33.82  LDD1905 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1905 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 46.85  LDD1905 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 44.63  LDD1905 
Beta-catenin-like protein 1 (CTNNBL1) LDTP09733 37.79  LDD1905 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 43.41  LDD1905 
BTB/POZ domain-containing protein KCTD12 (KCTD12) LDTP15705 33.13  LDD1905 
Calumenin (CALU) LDTP00887 77.17  LDD1905 
CCR4-NOT transcription complex subunit 9 (CNOT9) LDTP09813 38.32  LDD1905 
Centrosomal protein 43 (CEP43) LDTP01652 33.59  LDD1905 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 56.10  LDD1905 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 33.59  LDD1905 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD1905 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 37.79  LDD1905 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 36.50  LDD1905 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 62.25  LDD1905 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 34.54  LDD1905 
Emerin (EMD) LDTP04356 39.95  LDD1905 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 88.03  LDD1905 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 92.41  LDD1905 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 37.27  LDD1905 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 33.82  LDD1905 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 42.81  LDD1905 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 33.13  LDD1905 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 63.12  LDD1905 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 38.85  LDD1905 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 41.36  LDD1905 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 75.58  LDD1905 
GRB10-interacting GYF protein 2 (GIGYF2) LDTP07758 33.13  LDD1905 
Guanine nucleotide-binding protein G(i) subunit alpha-1 (GNAI1) LDTP05041 40.79  LDD1905 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 33.82  LDD1905 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) LDTP05054 33.59  LDD1905 
HCLS1-associated protein X-1 (HAX1) LDTP00199 58.49  LDD1905 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 47.84  LDD1905 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 37.01  LDD1905 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 60.13  LDD1905 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 39.67  LDD1905 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 35.75  LDD1905 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 52.35  LDD1905 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 44.32  LDD1905 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 60.13  LDD1905 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 37.79  LDD1905 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 33.36  LDD1905 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 44.02  LDD1905 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 38.59  LDD1905 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 37.53  LDD1905 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 35.02  LDD1905 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 37.79  LDD1905 
Jupiter microtubule associated homolog 2 (JPT2) LDTP12077 39.40  LDD1905 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 44.02  LDD1905 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 99.73  LDD1905 
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) LDTP05525 39.12  LDD1905 
Kinetochore protein Spc24 (SPC24) LDTP09069 42.22  LDD1905 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 35.51  LDD1905 
Large ribosomal subunit protein mL46 (MRPL46) LDTP15976 37.27  LDD1905 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 73.52  LDD1905 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 56.10  LDD1905 
Matrin-3 (MATR3) LDTP04027 34.78  LDD1905 
Membralin (TMEM259) LDTP14939 71.01  LDD1905 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 54.19  LDD1905 
MICOS complex subunit MIC27 (APOOL) LDTP07718 33.13  LDD1905 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 39.95  LDD1905 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 35.51  LDD1905 
Mitochondrial fission 1 protein (FIS1) LDTP13982 57.28  LDD1905 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 50.56  LDD1905 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 37.27  LDD1905 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 51.63  LDD1905 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 35.02  LDD1905 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 79.34  LDD1905 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 96.34  LDD1905 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 36.76  LDD1905 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 53.82  LDD1905 
Myosin light chain 6B (MYL6B) LDTP02736 38.32  LDD1905 
Negative elongation factor C/D (NELFCD) LDTP08594 43.41  LDD1905 
Nestin (NES) LDTP04206 36.76  LDD1905 
Neurofilament light polypeptide (NEFL) LDTP02180 39.40  LDD1905 
NLR family member X1 (NLRX1) LDTP08248 99.73  LDD1905 
Nuclear nucleic acid-binding protein C1D (C1D) LDTP06004 60.97  LDD1905 
Nucleobindin-2 (NUCB2) LDTP05160 78.25  LDD1905 
Nucleolysin TIAR (TIAL1) LDTP05274 35.02  LDD1905 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 33.13  LDD1905 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 52.35  LDD1905 
Optic atrophy 3 protein (OPA3) LDTP16006 77.17  LDD1905 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 42.22  LDD1905 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 95.01  LDD1905 
Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1) LDTP07655 53.45  LDD1905 
Programmed cell death protein 5 (PDCD5) LDTP00417 38.85  LDD1905 
Protein CutA (CUTA) LDTP01075 70.52  LDD1905 
Protein ecdysoneless homolog (ECD) LDTP01711 39.95  LDD1905 
Protein FAM114A2 (FAM114A2) LDTP16080 45.25  LDD1905 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD1905 
Protein LYRIC (MTDH) LDTP08224 57.68  LDD1905 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 36.76  LDD1905 
Protein NipSnap homolog 1 (NIPSNAP1) LDTP19912 35.02  LDD1905 
Protein PRRC1 (PRRC1) LDTP15778 41.36  LDD1905 
Protein SET (SET) LDTP05277 44.32  LDD1905 
Protein SSXT (SS18) LDTP06406 48.84  LDD1905 
Protein YIF1A (YIF1A) LDTP01494 96.34  LDD1905 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 35.51  LDD1905 
Reticulocalbin-2 (RCN2) LDTP06097 79.34  LDD1905 
Reticulon-3 (RTN3) LDTP01522 74.03  LDD1905 
Reticulon-4 (RTN4) LDTP12412 45.25  LDD1905 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 47.50  LDD1905 
RNA-binding protein 14 (RBM14) LDTP10684 33.82  LDD1905 
RNA-binding protein 3 (RBM3) LDTP05226 55.33  LDD1905 
RNA-binding protein EWS (EWSR1) LDTP05318 41.07  LDD1905 
RNA-binding protein FUS (FUS) LDTP03775 64.89  LDD1905 
Striatin (STRN) LDTP00875 51.63  LDD1905 
Synaptogyrin-2 (SYNGR2) LDTP00859 48.17  LDD1905 
Syntaxin-18 (STX18) LDTP13086 48.50  LDD1905 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 70.52  LDD1905 
Tetraspanin-6 (TSPAN6) LDTP14458 91.14  LDD1905 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 35.02  LDD1905 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 38.85  LDD1905 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 56.89  LDD1905 
TraB domain-containing protein (TRABD) LDTP19963 68.59  LDD1905 
Transformer-2 protein homolog alpha (TRA2A) LDTP05937 39.12  LDD1905 
Transformer-2 protein homolog beta (TRA2B) LDTP05036 37.53  LDD1905 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 48.17  LDD1905 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 40.50  LDD1905 
Vimentin (VIM) LDTP02297 47.84  LDD1905 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1905 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587