General Information of Target

Target ID LDTP09059
Target Name Protein O-glucosyltransferase 1 (POGLUT1)
Gene Name POGLUT1
Gene ID 56983
Synonyms
C3orf9; CLP46; KTELC1; MDSRP; Protein O-glucosyltransferase 1; EC 2.4.1.376; CAP10-like 46 kDa protein; hCLP46; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein; O-glucosyltransferase Rumi homolog; hRumi; Protein O-xylosyltransferase POGLUT1; EC 2.4.2.63
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEWWASSPLRLWLLLFLLPSAQGRQKESGSKWKVFIDQINRSLENYEPCSSQNCSCYHGV
IEEDLTPFRGGISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCSGVEHFILEVIG
RLPDMEMVINVRDYPQVPKWMEPAIPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPIYPTG
LGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQ
AWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWLEF
FYPQLKPWVHYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDDITCYWE
NLLSEYSKFLSYNVTRRKGYDQIIPKMLKTEL
Target Bioclass
Enzyme
Family
Glycosyltransferase 90 family
Subcellular location
Endoplasmic reticulum lumen
Function
Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane.
Uniprot ID
Q8NBL1
Ensemble ID
ENST00000295588.9
HGNC ID
HGNC:22954

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C102(1.19)  LDD0812  [1]
4-Iodoacetamidophenylacetylene
 Probe Info 
C108(0.00); C102(0.00); C357(0.00); C263(0.00)  LDD0038  [2]
IA-alkyne
 Probe Info 
N.A.  LDD0032  [3]
Lodoacetamide azide
 Probe Info 
C108(0.00); C263(0.00); C102(0.00); C357(0.00)  LDD0037  [2]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C231
 Probe Info 
11.63  LDD1904  [4]
C232
 Probe Info 
44.02  LDD1905  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C102(1.19)  LDD0812  [1]
 LDCM0215  AC10 HEK-293T C102(0.92)  LDD0813  [1]
 LDCM0216  AC100 HEK-293T C102(0.89)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C102(0.99)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C102(0.98)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C102(1.04)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C102(1.08)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C102(1.04)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C102(1.21)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C102(1.00)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C102(1.00)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C102(0.95)  LDD0823  [1]
 LDCM0226  AC11 HEK-293T C102(0.87)  LDD0824  [1]
 LDCM0227  AC110 HEK-293T C102(0.94)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C102(1.10)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C102(1.01)  LDD0827  [1]
 LDCM0237  AC12 HEK-293T C102(0.91)  LDD0835  [1]
 LDCM0259  AC14 HEK-293T C102(0.91)  LDD0857  [1]
 LDCM0270  AC15 HEK-293T C102(0.80)  LDD0868  [1]
 LDCM0276  AC17 HEK-293T C102(0.60)  LDD0874  [1]
 LDCM0277  AC18 HEK-293T C102(0.68)  LDD0875  [1]
 LDCM0278  AC19 HEK-293T C102(0.81)  LDD0876  [1]
 LDCM0279  AC2 HEK-293T C102(0.77)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C102(0.66)  LDD0878  [1]
 LDCM0281  AC21 HEK-293T C102(0.70)  LDD0879  [1]
 LDCM0282  AC22 HEK-293T C102(0.56)  LDD0880  [1]
 LDCM0283  AC23 HEK-293T C102(0.53)  LDD0881  [1]
 LDCM0284  AC24 HEK-293T C102(0.65)  LDD0882  [1]
 LDCM0285  AC25 HEK-293T C263(1.05); C108(0.98); C357(1.14); C102(0.89)  LDD1524  [5]
 LDCM0286  AC26 HEK-293T C263(0.98); C108(1.07); C102(1.04)  LDD1525  [5]
 LDCM0287  AC27 HEK-293T C263(1.03); C108(0.94)  LDD1526  [5]
 LDCM0288  AC28 HEK-293T C263(1.01); C108(0.99); C102(1.00)  LDD1527  [5]
 LDCM0289  AC29 HEK-293T C263(0.90); C108(1.10); C102(1.13)  LDD1528  [5]
 LDCM0290  AC3 HEK-293T C102(0.99)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C263(0.98); C108(1.09); C357(0.86); C102(1.03)  LDD1530  [5]
 LDCM0292  AC31 HEK-293T C263(0.98); C108(0.97); C357(1.22); C102(1.02)  LDD1531  [5]
 LDCM0293  AC32 HEK-293T C263(0.92); C108(1.11); C357(1.18); C102(0.97)  LDD1532  [5]
 LDCM0294  AC33 HEK-293T C263(1.11); C108(1.01); C357(1.11); C102(0.97)  LDD1533  [5]
 LDCM0295  AC34 HEK-293T C263(0.96); C108(1.03); C102(1.10)  LDD1534  [5]
 LDCM0296  AC35 HEK-293T C263(0.99); C108(0.95)  LDD1535  [5]
 LDCM0297  AC36 HEK-293T C263(1.07); C108(1.05); C102(1.01)  LDD1536  [5]
 LDCM0298  AC37 HEK-293T C263(0.95); C108(1.26); C102(1.07)  LDD1537  [5]
 LDCM0299  AC38 HEK-293T C263(0.99); C108(1.07); C357(1.19); C102(1.00)  LDD1538  [5]
 LDCM0300  AC39 HEK-293T C263(1.04); C108(0.95); C357(1.11); C102(1.03)  LDD1539  [5]
 LDCM0301  AC4 HEK-293T C102(1.27)  LDD0899  [1]
 LDCM0302  AC40 HEK-293T C263(0.99); C108(0.97); C357(1.09); C102(0.96)  LDD1541  [5]
 LDCM0303  AC41 HEK-293T C263(1.09); C108(1.00); C357(1.17); C102(0.95)  LDD1542  [5]
 LDCM0304  AC42 HEK-293T C263(1.04); C108(1.10); C102(1.11)  LDD1543  [5]
 LDCM0305  AC43 HEK-293T C263(1.03); C108(1.01)  LDD1544  [5]
 LDCM0306  AC44 HEK-293T C263(1.03); C108(1.07); C102(0.90)  LDD1545  [5]
 LDCM0307  AC45 HEK-293T C263(0.98); C108(1.02); C102(1.10)  LDD1546  [5]
 LDCM0308  AC46 HEK-293T C263(0.92); C108(1.12); C357(1.76); C102(1.08)  LDD1547  [5]
 LDCM0309  AC47 HEK-293T C263(1.10); C108(0.96); C357(1.55); C102(1.06)  LDD1548  [5]
 LDCM0310  AC48 HEK-293T C263(0.98); C108(0.93); C357(1.05); C102(1.01)  LDD1549  [5]
 LDCM0311  AC49 HEK-293T C263(1.08); C108(0.99); C357(1.16); C102(0.98)  LDD1550  [5]
 LDCM0312  AC5 HEK-293T C102(1.13)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C263(0.97); C108(1.15); C102(1.04)  LDD1552  [5]
 LDCM0314  AC51 HEK-293T C263(0.96); C108(0.95)  LDD1553  [5]
 LDCM0315  AC52 HEK-293T C263(1.00); C108(0.91); C102(0.91)  LDD1554  [5]
 LDCM0316  AC53 HEK-293T C263(0.93); C108(1.07); C102(1.23)  LDD1555  [5]
 LDCM0317  AC54 HEK-293T C263(0.94); C108(1.12); C357(1.25); C102(1.07)  LDD1556  [5]
 LDCM0318  AC55 HEK-293T C263(1.05); C108(1.10); C357(1.24); C102(1.07)  LDD1557  [5]
 LDCM0319  AC56 HEK-293T C263(1.05); C108(1.11); C357(1.07); C102(0.99)  LDD1558  [5]
 LDCM0320  AC57 HEK-293T C263(1.15); C108(1.13); C357(1.13); C102(0.96)  LDD1559  [5]
 LDCM0321  AC58 HEK-293T C263(1.00); C108(1.07); C102(0.94)  LDD1560  [5]
 LDCM0322  AC59 HEK-293T C263(0.91); C108(1.14)  LDD1561  [5]
 LDCM0323  AC6 HEK-293T C102(1.11)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C263(1.03); C108(1.00); C102(0.93)  LDD1563  [5]
 LDCM0325  AC61 HEK-293T C263(1.01); C108(1.07); C102(1.05)  LDD1564  [5]
 LDCM0326  AC62 HEK-293T C263(1.00); C108(1.14); C357(1.03); C102(1.01)  LDD1565  [5]
 LDCM0327  AC63 HEK-293T C263(1.04); C108(1.07); C357(1.06); C102(1.00)  LDD1566  [5]
 LDCM0328  AC64 HEK-293T C263(1.00); C108(0.95); C357(1.08); C102(1.12)  LDD1567  [5]
 LDCM0334  AC7 HEK-293T C102(0.92)  LDD0932  [1]
 LDCM0345  AC8 HEK-293T C102(0.92)  LDD0943  [1]
 LDCM0365  AC98 HEK-293T C102(0.93)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C102(0.90)  LDD0964  [1]
 LDCM0248  AKOS034007472 HEK-293T C102(0.97)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C102(0.91)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C102(0.87)  LDD0873  [1]
 LDCM0367  CL1 HEK-293T C263(1.28); C108(1.14); C357(1.08)  LDD1571  [5]
 LDCM0368  CL10 HEK-293T C263(1.95); C108(0.22); C357(1.46); C102(1.27)  LDD1572  [5]
 LDCM0369  CL100 HEK-293T C102(0.87)  LDD0967  [1]
 LDCM0370  CL101 HEK-293T C102(0.92)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C102(0.89)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C102(0.80)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C102(1.01)  LDD0971  [1]
 LDCM0374  CL105 HEK-293T C102(0.68)  LDD0972  [1]
 LDCM0375  CL106 HEK-293T C102(0.76)  LDD0973  [1]
 LDCM0376  CL107 HEK-293T C102(0.86)  LDD0974  [1]
 LDCM0377  CL108 HEK-293T C102(0.65)  LDD0975  [1]
 LDCM0378  CL109 HEK-293T C102(0.82)  LDD0976  [1]
 LDCM0379  CL11 HEK-293T C263(1.43); C108(0.93); C357(1.55); C102(1.05)  LDD1583  [5]
 LDCM0380  CL110 HEK-293T C102(0.75)  LDD0978  [1]
 LDCM0381  CL111 HEK-293T C102(0.63)  LDD0979  [1]
 LDCM0382  CL112 HEK-293T C108(0.94); C102(1.04)  LDD1586  [5]
 LDCM0383  CL113 HEK-293T C263(1.09); C108(1.13); C357(1.03)  LDD1587  [5]
 LDCM0384  CL114 HEK-293T C263(1.31); C108(1.20); C102(1.09)  LDD1588  [5]
 LDCM0385  CL115 HEK-293T C263(1.08); C108(0.94); C357(0.91)  LDD1589  [5]
 LDCM0386  CL116 HEK-293T C108(1.00); C102(1.10)  LDD1590  [5]
 LDCM0387  CL117 HEK-293T C263(1.12); C108(1.05); C357(0.92)  LDD1591  [5]
 LDCM0388  CL118 HEK-293T C263(1.11); C108(1.21); C102(1.18)  LDD1592  [5]
 LDCM0389  CL119 HEK-293T C263(1.05); C108(1.16); C357(0.99)  LDD1593  [5]
 LDCM0390  CL12 HEK-293T C263(1.44); C108(0.97); C357(1.09); C102(1.12)  LDD1594  [5]
 LDCM0391  CL120 HEK-293T C108(0.90); C102(1.09)  LDD1595  [5]
 LDCM0392  CL121 HEK-293T C263(1.14); C108(1.03); C357(0.94)  LDD1596  [5]
 LDCM0393  CL122 HEK-293T C263(1.13); C108(1.17); C102(0.91)  LDD1597  [5]
 LDCM0394  CL123 HEK-293T C263(1.32); C108(1.19); C357(1.36)  LDD1598  [5]
 LDCM0395  CL124 HEK-293T C108(1.01); C102(1.02)  LDD1599  [5]
 LDCM0396  CL125 HEK-293T C263(1.09); C108(1.02); C357(1.02)  LDD1600  [5]
 LDCM0397  CL126 HEK-293T C263(1.12); C108(0.98); C102(0.96)  LDD1601  [5]
 LDCM0398  CL127 HEK-293T C263(1.05); C108(0.92); C357(0.86)  LDD1602  [5]
 LDCM0399  CL128 HEK-293T C108(1.03); C102(0.99)  LDD1603  [5]
 LDCM0400  CL13 HEK-293T C263(1.20); C108(1.09); C357(1.07)  LDD1604  [5]
 LDCM0401  CL14 HEK-293T C263(1.06); C108(0.68); C102(0.96)  LDD1605  [5]
 LDCM0402  CL15 HEK-293T C263(1.33); C108(0.20); C357(0.91)  LDD1606  [5]
 LDCM0403  CL16 HEK-293T C102(1.70)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C102(1.82)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C102(1.28)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C102(0.93)  LDD1004  [1]
 LDCM0407  CL2 HEK-293T C263(1.04); C108(1.02); C102(0.94)  LDD1611  [5]
 LDCM0408  CL20 HEK-293T C102(1.01)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C102(1.01)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C102(0.92)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C102(1.00)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C102(1.08)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C102(0.91)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C102(0.96)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C102(0.85)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C102(0.97)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C102(1.01)  LDD1015  [1]
 LDCM0418  CL3 HEK-293T C263(1.12); C108(1.05); C357(1.07)  LDD1622  [5]
 LDCM0419  CL30 HEK-293T C102(0.91)  LDD1017  [1]
 LDCM0420  CL31 HEK-293T C263(1.25); C108(0.89)  LDD1624  [5]
 LDCM0421  CL32 HEK-293T C263(1.09); C108(0.96); C102(0.91)  LDD1625  [5]
 LDCM0422  CL33 HEK-293T C263(1.79); C108(0.95); C102(0.87)  LDD1626  [5]
 LDCM0423  CL34 HEK-293T C263(1.27); C108(0.92); C357(1.12); C102(1.11)  LDD1627  [5]
 LDCM0424  CL35 HEK-293T C263(1.30); C108(0.91); C357(1.33); C102(1.04)  LDD1628  [5]
 LDCM0425  CL36 HEK-293T C263(1.28); C108(0.81); C357(1.20); C102(0.86)  LDD1629  [5]
 LDCM0426  CL37 HEK-293T C263(1.12); C108(1.00); C357(1.03)  LDD1630  [5]
 LDCM0428  CL39 HEK-293T C263(1.27); C108(1.10); C357(1.04)  LDD1632  [5]
 LDCM0429  CL4 HEK-293T C108(0.81); C102(1.01)  LDD1633  [5]
 LDCM0430  CL40 HEK-293T C108(0.82); C102(0.98)  LDD1634  [5]
 LDCM0431  CL41 HEK-293T C263(1.32); C108(0.97); C357(1.06); C102(1.05)  LDD1635  [5]
 LDCM0432  CL42 HEK-293T C263(1.01); C108(1.04); C102(1.06)  LDD1636  [5]
 LDCM0433  CL43 HEK-293T C263(1.04); C108(0.94)  LDD1637  [5]
 LDCM0434  CL44 HEK-293T C263(1.10); C108(1.02); C102(0.94)  LDD1638  [5]
 LDCM0435  CL45 HEK-293T C263(1.33); C108(0.99); C102(1.22)  LDD1639  [5]
 LDCM0436  CL46 HEK-293T C102(0.95)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C102(0.83)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C102(0.96)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C102(0.84)  LDD1037  [1]
 LDCM0440  CL5 HEK-293T C263(1.08); C108(0.95); C357(1.18); C102(1.07)  LDD1644  [5]
 LDCM0441  CL50 HEK-293T C102(0.83)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C102(0.96)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C102(0.82)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C102(0.72)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C102(0.89)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C102(0.75)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C102(0.76)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C102(0.76)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C102(0.67)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C102(0.75)  LDD1048  [1]
 LDCM0451  CL6 HEK-293T C263(1.22); C108(1.15); C102(1.13)  LDD1654  [5]
 LDCM0452  CL60 HEK-293T C102(0.81)  LDD1050  [1]
 LDCM0453  CL61 HEK-293T C102(1.06)  LDD1051  [1]
 LDCM0454  CL62 HEK-293T C102(0.90)  LDD1052  [1]
 LDCM0455  CL63 HEK-293T C102(1.08)  LDD1053  [1]
 LDCM0456  CL64 HEK-293T C102(1.05)  LDD1054  [1]
 LDCM0457  CL65 HEK-293T C102(0.95)  LDD1055  [1]
 LDCM0458  CL66 HEK-293T C102(0.95)  LDD1056  [1]
 LDCM0459  CL67 HEK-293T C102(0.85)  LDD1057  [1]
 LDCM0460  CL68 HEK-293T C102(0.85)  LDD1058  [1]
 LDCM0461  CL69 HEK-293T C102(0.97)  LDD1059  [1]
 LDCM0462  CL7 HEK-293T C263(1.17); C108(0.93)  LDD1665  [5]
 LDCM0463  CL70 HEK-293T C102(0.86)  LDD1061  [1]
 LDCM0464  CL71 HEK-293T C102(0.78)  LDD1062  [1]
 LDCM0465  CL72 HEK-293T C102(0.94)  LDD1063  [1]
 LDCM0466  CL73 HEK-293T C102(0.76)  LDD1064  [1]
 LDCM0467  CL74 HEK-293T C102(0.96)  LDD1065  [1]
 LDCM0469  CL76 HEK-293T C102(1.13)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C102(1.23)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C102(2.05)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C102(1.64)  LDD1070  [1]
 LDCM0473  CL8 HEK-293T C263(2.03); C108(1.02); C102(1.46)  LDD1676  [5]
 LDCM0474  CL80 HEK-293T C102(1.26)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C102(1.46)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C102(0.92)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C102(0.84)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C102(1.46)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C102(1.77)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C102(1.88)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C102(1.69)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C102(1.03)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C102(1.36)  LDD1081  [1]
 LDCM0484  CL9 HEK-293T C263(1.07); C108(0.95); C102(1.17)  LDD1687  [5]
 LDCM0485  CL90 HEK-293T C102(1.05)  LDD1083  [1]
 LDCM0486  CL91 HEK-293T C102(1.59)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C102(1.20)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C102(1.46)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C102(0.98)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C102(1.00)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C102(1.39)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C102(1.24)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C102(1.19)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C102(1.02)  LDD1092  [1]
 LDCM0495  E2913 HEK-293T C263(1.11); C108(0.98); C357(1.27)  LDD1698  [5]
 LDCM0468  Fragment33 HEK-293T C102(0.82)  LDD1066  [1]
 LDCM0427  Fragment51 HEK-293T C263(1.04); C108(1.05); C102(0.94)  LDD1631  [5]
 LDCM0022  KB02 HEK-293T C263(0.91); C102(0.97); C357(0.92)  LDD1492  [5]
 LDCM0023  KB03 HEK-293T C263(0.92); C102(1.01); C357(0.93)  LDD1497  [5]
 LDCM0024  KB05 HEK-293T C263(0.93); C102(0.90); C357(0.93)  LDD1502  [5]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402