Details of the Target

General Information of Target

Target ID LDTP11494
Target Name Neurolysin, mitochondrial (NLN)
Gene Name NLN
Gene ID 57486
Synonyms
AGTBP; KIAA1226; Neurolysin, mitochondrial; EC 3.4.24.16; Angiotensin-binding protein; Microsomal endopeptidase; MEP; Mitochondrial oligopeptidase M; Neurotensin endopeptidase
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERK
KEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGR
ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQ
VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK
LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY
SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ
LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPS
TEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAE
IKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
Target Bioclass
Enzyme
Family
Peptidase M3 family
Subcellular location
Mitochondrion intermembrane space
Function
Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. Acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1.
Uniprot ID
Q9BYT8
Ensemble ID
ENST00000380985.10
HGNC ID
HGNC:16058

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 24 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Alkylaryl probe 3
 Probe Info  		20.00  LDD0381  [1]
TH211
 Probe Info  		Y446(8.72); Y245(7.10)  LDD0257  [2]
TH214
 Probe Info  		Y245(7.10)  LDD0258  [2]
TH216
 Probe Info  		Y245(20.00)  LDD0259  [2]
STPyne
 Probe Info  		K253(1.85); K325(10.00); K693(2.20)  LDD0277  [3]
Probe 1
 Probe Info  		Y352(11.27); Y373(73.87)  LDD3495  [4]
Alkylaryl probe 2
 Probe Info  		11.00  LDD0392  [1]
BTD
 Probe Info  		C153(2.16)  LDD1700  [5]
HHS-475
 Probe Info  		Y245(0.91)  LDD0264  [6]
HHS-465
 Probe Info  		Y245(8.34)  LDD2237  [7]
DBIA
 Probe Info  		C199(1.02); C451(0.87); C458(0.87); C153(0.87)  LDD0078  [8]
ATP probe
 Probe Info  		K157(0.00); K159(0.00); K253(0.00); K254(0.00)  LDD0199  [9]
4-Iodoacetamidophenylacetylene
 Probe Info  		C272(0.00); C153(0.00); C199(0.00)  LDD0038  [10]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [11]
Lodoacetamide azide
 Probe Info  		C272(0.00); C153(0.00); C199(0.00)  LDD0037  [10]
NAIA_4
 Probe Info  		N.A.  LDD2226  [12]
IPM
 Probe Info  		N.A.  LDD0005  [13]
SF
 Probe Info  		N.A.  LDD0028  [14]
Phosphinate-6
 Probe Info  		C255(0.00); C256(0.00)  LDD0018  [15]
Acrolein
 Probe Info  		C199(0.00); C153(0.00); H148(0.00)  LDD0217  [16]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [16]
Methacrolein
 Probe Info  		C153(0.00); C199(0.00)  LDD0218  [16]
NAIA_5
 Probe Info  		C272(0.00); C153(0.00)  LDD2223  [12]
HHS-482
 Probe Info  		Y245(1.12)  LDD2239  [7]
PAL-AfBPP Probe
Click To Hide/Show 16 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C017
 Probe Info  		6.68  LDD1725  [17]
C040
 Probe Info  		17.75  LDD1740  [17]
C131
 Probe Info  		5.46  LDD1813  [17]
C158
 Probe Info  		12.13  LDD1838  [17]
C231
 Probe Info  		13.45  LDD1904  [17]
C232
 Probe Info  		99.73  LDD1905  [17]
C277
 Probe Info  		9.65  LDD1947  [17]
C348
 Probe Info  		15.56  LDD2009  [17]
C353
 Probe Info  		6.50  LDD2014  [17]
C383
 Probe Info  		14.22  LDD2042  [17]
C403
 Probe Info  		16.11  LDD2061  [17]
FFF probe11
 Probe Info  		5.87  LDD0472  [18]
FFF probe13
 Probe Info  		6.82  LDD0476  [18]
FFF probe2
 Probe Info  		20.00  LDD0463  [18]
FFF probe3
 Probe Info  		16.06  LDD0465  [18]
VE-P
 Probe Info  		N.A.  LDD0396  [19]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C256(0.74); C255(0.62)  LDD2142  [5]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C256(0.73); C255(0.90); C153(0.61)  LDD2112  [5]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C256(0.70); C255(0.67); C153(0.94)  LDD2117  [5]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C256(0.92); C153(1.22)  LDD2152  [5]
 LDCM0214  AC1 HCT 116 C153(1.06); C199(1.03); C255(1.05); C256(0.98)  LDD0531  [8]
 LDCM0215  AC10 HCT 116 C153(1.05); C199(1.03); C255(1.64); C256(1.64)  LDD0532  [8]
 LDCM0216  AC100 HCT 116 C153(0.94); C199(1.10); C255(0.38); C256(0.38)  LDD0533  [8]
 LDCM0217  AC101 HCT 116 C153(0.88); C199(1.13); C255(0.39); C256(0.39)  LDD0534  [8]
 LDCM0218  AC102 HCT 116 C153(0.89); C199(1.07); C255(0.57); C256(0.57)  LDD0535  [8]
 LDCM0219  AC103 HCT 116 C153(0.79); C199(1.31); C255(0.34); C256(0.34)  LDD0536  [8]
 LDCM0220  AC104 HCT 116 C153(0.90); C199(1.17); C255(0.88); C256(0.88)  LDD0537  [8]
 LDCM0221  AC105 HCT 116 C153(0.88); C199(1.18); C255(0.42); C256(0.42)  LDD0538  [8]
 LDCM0222  AC106 HCT 116 C153(0.83); C199(1.20); C255(0.30); C256(0.30)  LDD0539  [8]
 LDCM0223  AC107 HCT 116 C153(0.89); C199(1.28); C255(0.41); C256(0.41)  LDD0540  [8]
 LDCM0224  AC108 HCT 116 C153(0.80); C199(1.03); C255(0.39); C256(0.39)  LDD0541  [8]
 LDCM0225  AC109 HCT 116 C153(0.81); C199(1.04); C255(0.84); C256(0.84)  LDD0542  [8]
 LDCM0226  AC11 HCT 116 C153(1.10); C199(0.97); C255(1.70); C256(1.70)  LDD0543  [8]
 LDCM0227  AC110 HCT 116 C153(0.80); C199(1.07); C255(0.34); C256(0.34)  LDD0544  [8]
 LDCM0228  AC111 HCT 116 C153(0.75); C199(1.19); C255(0.31); C256(0.31)  LDD0545  [8]
 LDCM0229  AC112 HCT 116 C153(0.86); C199(1.23); C255(0.42); C256(0.42)  LDD0546  [8]
 LDCM0230  AC113 HCT 116 C153(1.06); C199(1.00); C255(1.00); C256(0.98)  LDD0547  [8]
 LDCM0231  AC114 HCT 116 C153(1.13); C199(1.00); C255(0.96); C256(0.97)  LDD0548  [8]
 LDCM0232  AC115 HCT 116 C153(1.05); C199(0.94); C255(0.82); C256(0.93)  LDD0549  [8]
 LDCM0233  AC116 HCT 116 C153(1.01); C199(1.06); C255(0.93); C256(1.07)  LDD0550  [8]
 LDCM0234  AC117 HCT 116 C153(1.18); C199(1.04); C255(1.00); C256(1.13)  LDD0551  [8]
 LDCM0235  AC118 HCT 116 C153(1.08); C199(1.09); C255(1.13); C256(1.09)  LDD0552  [8]
 LDCM0236  AC119 HCT 116 C153(1.06); C199(1.03); C255(0.98); C256(0.96)  LDD0553  [8]
 LDCM0237  AC12 HCT 116 C153(1.03); C199(0.95); C255(2.00); C256(2.00)  LDD0554  [8]
 LDCM0238  AC120 HCT 116 C153(1.04); C199(1.04); C255(1.16); C256(1.04)  LDD0555  [8]
 LDCM0239  AC121 HCT 116 C153(0.97); C199(0.97); C255(1.31); C256(1.27)  LDD0556  [8]
 LDCM0240  AC122 HCT 116 C153(1.11); C199(0.93); C255(1.15); C256(1.07)  LDD0557  [8]
 LDCM0241  AC123 HCT 116 C153(1.01); C199(0.90); C255(1.21); C256(1.10)  LDD0558  [8]
 LDCM0242  AC124 HCT 116 C153(1.06); C199(1.02); C255(1.13); C256(1.27)  LDD0559  [8]
 LDCM0243  AC125 HCT 116 C153(1.10); C199(1.03); C255(1.18); C256(1.07)  LDD0560  [8]
 LDCM0244  AC126 HCT 116 C153(1.06); C199(1.12); C255(1.17); C256(0.92)  LDD0561  [8]
 LDCM0245  AC127 HCT 116 C153(1.11); C199(0.94); C255(1.27); C256(1.12)  LDD0562  [8]
 LDCM0246  AC128 HCT 116 C153(0.97); C199(1.43); C255(1.02); C256(1.24)  LDD0563  [8]
 LDCM0247  AC129 HCT 116 C153(1.09); C199(1.17); C255(0.91); C256(0.95)  LDD0564  [8]
 LDCM0249  AC130 HCT 116 C153(1.00); C199(1.18); C255(0.78); C256(0.87)  LDD0566  [8]
 LDCM0250  AC131 HCT 116 C153(1.03); C199(1.02); C255(0.92); C256(0.97)  LDD0567  [8]
 LDCM0251  AC132 HCT 116 C153(1.13); C199(1.19); C255(0.60); C256(0.57)  LDD0568  [8]
 LDCM0252  AC133 HCT 116 C153(1.10); C199(1.32); C255(0.74); C256(0.82)  LDD0569  [8]
 LDCM0253  AC134 HCT 116 C153(1.08); C199(1.21); C255(0.59); C256(0.56)  LDD0570  [8]
 LDCM0254  AC135 HCT 116 C153(1.00); C199(1.12); C255(0.74); C256(0.79)  LDD0571  [8]
 LDCM0255  AC136 HCT 116 C153(1.03); C199(1.23); C255(0.56); C256(0.52)  LDD0572  [8]
 LDCM0256  AC137 HCT 116 C153(1.16); C199(1.43); C255(0.63); C256(0.66)  LDD0573  [8]
 LDCM0257  AC138 HCT 116 C153(0.94); C199(1.19); C255(0.42); C256(0.36)  LDD0574  [8]
 LDCM0258  AC139 HCT 116 C153(0.93); C199(1.20); C255(0.53); C256(0.51)  LDD0575  [8]
 LDCM0259  AC14 HCT 116 C153(1.11); C199(0.98); C255(1.70); C256(1.70)  LDD0576  [8]
 LDCM0260  AC140 HCT 116 C153(0.98); C199(1.31); C255(0.45); C256(0.37)  LDD0577  [8]
 LDCM0261  AC141 HCT 116 C153(1.06); C199(1.22); C255(0.44); C256(0.37)  LDD0578  [8]
 LDCM0262  AC142 HCT 116 C153(1.06); C199(1.22); C255(0.56); C256(0.54)  LDD0579  [8]
 LDCM0263  AC143 HCT 116 C451(0.78); C458(0.78); C256(0.79); C255(0.80)  LDD0580  [8]
 LDCM0264  AC144 HCT 116 C458(0.66); C255(0.68); C256(0.81); C451(0.94)  LDD0581  [8]
 LDCM0265  AC145 HCT 116 C458(0.68); C256(0.75); C153(0.91); C451(0.92)  LDD0582  [8]
 LDCM0266  AC146 HCT 116 C256(0.59); C451(0.70); C255(0.79); C458(0.87)  LDD0583  [8]
 LDCM0267  AC147 HCT 116 C458(0.61); C153(0.91); C255(1.03); C256(1.12)  LDD0584  [8]
 LDCM0268  AC148 HCT 116 C256(0.51); C451(0.65); C458(0.67); C255(0.84)  LDD0585  [8]
 LDCM0269  AC149 HCT 116 C256(0.49); C451(0.67); C458(0.81); C255(0.87)  LDD0586  [8]
 LDCM0270  AC15 HCT 116 C451(0.72); C458(0.72); C199(1.04); C153(1.07)  LDD0587  [8]
 LDCM0271  AC150 HCT 116 C458(0.69); C451(0.73); C256(0.81); C255(0.87)  LDD0588  [8]
 LDCM0272  AC151 HCT 116 C256(0.63); C451(0.81); C458(0.83); C255(0.85)  LDD0589  [8]
 LDCM0273  AC152 HCT 116 C255(0.43); C256(0.57); C458(0.77); C451(0.82)  LDD0590  [8]
 LDCM0274  AC153 HCT 116 C256(0.42); C451(0.47); C255(0.62); C458(0.71)  LDD0591  [8]
 LDCM0621  AC154 HCT 116 C153(1.06); C199(1.12); C255(0.68); C256(0.66)  LDD2158  [8]
 LDCM0622  AC155 HCT 116 C153(1.06); C199(1.06); C255(0.59); C256(0.54)  LDD2159  [8]
 LDCM0623  AC156 HCT 116 C153(1.05); C199(0.93); C255(0.71); C256(0.65)  LDD2160  [8]
 LDCM0624  AC157 HCT 116 C153(0.98); C199(0.99); C255(0.67); C256(0.59)  LDD2161  [8]
 LDCM0276  AC17 HCT 116 C255(0.87); C256(0.97); C153(1.02); C451(1.11)  LDD0593  [8]
 LDCM0277  AC18 HCT 116 C255(0.58); C199(0.67); C451(0.77); C458(0.77)  LDD0594  [8]
 LDCM0278  AC19 HCT 116 C199(0.76); C255(0.81); C256(0.97); C451(0.97)  LDD0595  [8]
 LDCM0279  AC2 HCT 116 C451(0.81); C458(0.81); C199(1.00); C153(1.01)  LDD0596  [8]
 LDCM0280  AC20 HCT 116 C255(0.67); C256(0.82); C451(0.89); C458(0.89)  LDD0597  [8]
 LDCM0281  AC21 HCT 116 C255(0.59); C199(0.81); C256(0.84); C153(0.87)  LDD0598  [8]
 LDCM0282  AC22 HCT 116 C255(0.63); C256(0.77); C199(0.94); C451(1.04)  LDD0599  [8]
 LDCM0283  AC23 HCT 116 C255(0.51); C451(0.91); C458(0.91); C256(0.94)  LDD0600  [8]
 LDCM0284  AC24 HCT 116 C199(0.76); C255(0.78); C451(1.06); C458(1.06)  LDD0601  [8]
 LDCM0285  AC25 HCT 116 C153(1.06); C199(1.07); C255(1.30); C256(1.30)  LDD0602  [8]
 LDCM0286  AC26 HCT 116 C255(0.77); C256(0.77); C451(0.88); C458(0.88)  LDD0603  [8]
 LDCM0287  AC27 HCT 116 C153(0.87); C451(1.11); C458(1.11); C255(1.13)  LDD0604  [8]
 LDCM0288  AC28 HCT 116 C451(0.82); C458(0.82); C153(0.85); C255(0.90)  LDD0605  [8]
 LDCM0289  AC29 HCT 116 C255(0.58); C256(0.58); C451(0.65); C458(0.65)  LDD0606  [8]
 LDCM0290  AC3 HCT 116 C451(0.94); C458(0.94); C256(1.01); C199(1.06)  LDD0607  [8]
 LDCM0291  AC30 HCT 116 C255(0.54); C256(0.54); C451(0.60); C458(0.60)  LDD0608  [8]
 LDCM0292  AC31 HCT 116 C255(0.73); C256(0.73); C153(0.81); C451(0.82)  LDD0609  [8]
 LDCM0293  AC32 HCT 116 C255(0.54); C256(0.54); C451(0.61); C458(0.61)  LDD0610  [8]
 LDCM0294  AC33 HCT 116 C153(0.91); C255(1.01); C256(1.01); C451(1.14)  LDD0611  [8]
 LDCM0295  AC34 HCT 116 C153(0.77); C255(0.99); C256(0.99); C199(1.23)  LDD0612  [8]
 LDCM0296  AC35 HCT 116 C153(0.94); C256(1.17); C255(1.34); C451(1.35)  LDD0613  [8]
 LDCM0297  AC36 HCT 116 C255(0.70); C256(0.86); C153(0.98); C451(1.16)  LDD0614  [8]
 LDCM0298  AC37 HCT 116 C153(1.01); C451(1.03); C458(1.03); C256(1.53)  LDD0615  [8]
 LDCM0299  AC38 HCT 116 C255(0.63); C256(0.80); C153(0.89); C451(1.14)  LDD0616  [8]
 LDCM0300  AC39 HCT 116 C255(0.71); C256(0.93); C153(0.99); C451(1.24)  LDD0617  [8]
 LDCM0301  AC4 HCT 116 C451(0.88); C458(0.88); C153(1.10); C256(1.14)  LDD0618  [8]
 LDCM0302  AC40 HCT 116 C255(0.77); C256(0.87); C153(0.88); C451(1.19)  LDD0619  [8]
 LDCM0303  AC41 HCT 116 C451(0.85); C458(0.85); C255(1.04); C153(1.06)  LDD0620  [8]
 LDCM0304  AC42 HCT 116 C255(0.83); C153(0.91); C256(0.96); C451(1.06)  LDD0621  [8]
 LDCM0305  AC43 HCT 116 C451(0.79); C458(0.79); C255(0.81); C153(1.00)  LDD0622  [8]
 LDCM0306  AC44 HCT 116 C451(0.79); C458(0.79); C153(0.91); C256(1.54)  LDD0623  [8]
 LDCM0307  AC45 HCT 116 C153(0.82); C451(0.94); C458(0.94); C256(1.36)  LDD0624  [8]
 LDCM0308  AC46 HCT 116 C255(0.62); C256(0.80); C153(0.93); C199(1.01)  LDD0625  [8]
 LDCM0309  AC47 HCT 116 C255(0.80); C256(0.84); C153(1.03); C199(1.04)  LDD0626  [8]
 LDCM0310  AC48 HCT 116 C255(0.75); C256(0.96); C153(0.96); C199(1.05)  LDD0627  [8]
 LDCM0311  AC49 HCT 116 C153(0.64); C255(0.73); C451(0.76); C458(0.76)  LDD0628  [8]
 LDCM0312  AC5 HCT 116 C451(0.75); C458(0.75); C256(0.99); C255(1.03)  LDD0629  [8]
 LDCM0313  AC50 HCT 116 C255(0.70); C153(0.71); C256(0.89); C451(0.96)  LDD0630  [8]
 LDCM0314  AC51 HCT 116 C255(0.78); C199(0.79); C153(0.94); C256(0.98)  LDD0631  [8]
 LDCM0315  AC52 HCT 116 C255(0.79); C256(0.90); C199(0.96); C153(1.09)  LDD0632  [8]
 LDCM0316  AC53 HCT 116 C153(0.80); C451(0.81); C458(0.81); C256(0.99)  LDD0633  [8]
 LDCM0317  AC54 HCT 116 C451(0.74); C458(0.74); C153(0.79); C255(0.88)  LDD0634  [8]
 LDCM0318  AC55 HCT 116 C451(0.59); C458(0.59); C153(0.64); C255(0.89)  LDD0635  [8]
 LDCM0319  AC56 HCT 116 C153(0.57); C451(0.62); C458(0.62); C255(0.70)  LDD0636  [8]
 LDCM0320  AC57 HCT 116 C255(0.92); C153(0.99); C199(1.00); C256(1.10)  LDD0637  [8]
 LDCM0321  AC58 HCT 116 C153(0.92); C255(1.01); C256(1.02); C199(1.02)  LDD0638  [8]
 LDCM0322  AC59 HCT 116 C255(0.69); C256(1.05); C153(1.06); C199(1.22)  LDD0639  [8]
 LDCM0323  AC6 HCT 116 C451(0.68); C458(0.68); C255(0.76); C256(0.76)  LDD0640  [8]
 LDCM0324  AC60 HCT 116 C255(0.91); C153(0.98); C256(1.13); C451(1.22)  LDD0641  [8]
 LDCM0325  AC61 HCT 116 C255(0.94); C153(1.02); C256(1.06); C199(1.10)  LDD0642  [8]
 LDCM0326  AC62 HCT 116 C255(0.82); C153(0.91); C199(1.01); C256(1.40)  LDD0643  [8]
 LDCM0327  AC63 HCT 116 C153(0.91); C255(0.91); C199(1.20); C256(1.26)  LDD0644  [8]
 LDCM0328  AC64 HCT 116 C255(0.82); C153(1.02); C199(1.10); C451(1.41)  LDD0645  [8]
 LDCM0329  AC65 HCT 116 C256(0.92); C451(0.92); C458(0.92); C255(0.95)  LDD0646  [8]
 LDCM0330  AC66 HCT 116 C451(0.97); C458(0.97); C255(0.98); C153(1.01)  LDD0647  [8]
 LDCM0331  AC67 HCT 116 C255(0.58); C153(1.00); C256(1.05); C451(1.11)  LDD0648  [8]
 LDCM0332  AC68 HCT 116 C153(0.89); C451(0.90); C458(0.90); C256(0.93)  LDD0649  [8]
 LDCM0333  AC69 HCT 116 C199(0.68); C153(0.95); C256(1.05); C255(1.11)  LDD0650  [8]
 LDCM0334  AC7 HCT 116 C451(0.84); C458(0.84); C255(1.02); C256(1.02)  LDD0651  [8]
 LDCM0335  AC70 HCT 116 C199(0.55); C255(0.61); C451(0.74); C458(0.74)  LDD0652  [8]
 LDCM0336  AC71 HCT 116 C199(0.87); C153(0.89); C451(0.89); C458(0.89)  LDD0653  [8]
 LDCM0337  AC72 HCT 116 C153(0.85); C255(0.93); C451(1.02); C458(1.02)  LDD0654  [8]
 LDCM0338  AC73 HCT 116 C451(0.62); C458(0.62); C255(0.68); C199(0.76)  LDD0655  [8]
 LDCM0339  AC74 HCT 116 C199(0.81); C255(0.84); C451(0.85); C458(0.85)  LDD0656  [8]
 LDCM0340  AC75 HCT 116 C451(0.64); C458(0.64); C255(0.65); C199(0.89)  LDD0657  [8]
 LDCM0341  AC76 HCT 116 C199(0.77); C153(0.84); C451(0.87); C458(0.87)  LDD0658  [8]
 LDCM0342  AC77 HCT 116 C199(0.77); C451(0.81); C458(0.81); C255(0.82)  LDD0659  [8]
 LDCM0343  AC78 HCT 116 C451(0.95); C458(0.95); C153(0.96); C256(1.00)  LDD0660  [8]
 LDCM0344  AC79 HCT 116 C199(0.84); C256(0.91); C153(0.97); C451(1.06)  LDD0661  [8]
 LDCM0345  AC8 HCT 116 C451(0.55); C458(0.55); C255(1.03); C256(1.03)  LDD0662  [8]
 LDCM0346  AC80 HCT 116 C199(0.77); C153(0.96); C255(0.98); C451(1.07)  LDD0663  [8]
 LDCM0347  AC81 HCT 116 C199(0.81); C451(0.88); C458(0.88); C153(0.89)  LDD0664  [8]
 LDCM0348  AC82 HCT 116 C451(0.65); C458(0.65); C255(0.76); C153(0.94)  LDD0665  [8]
 LDCM0349  AC83 HCT 116 C256(0.49); C451(0.67); C458(0.67); C255(0.75)  LDD0666  [8]
 LDCM0350  AC84 HCT 116 C256(0.50); C451(0.63); C458(0.63); C255(0.73)  LDD0667  [8]
 LDCM0351  AC85 HCT 116 C153(0.54); C451(0.62); C458(0.62); C256(0.99)  LDD0668  [8]
 LDCM0352  AC86 HCT 116 C153(0.60); C451(0.75); C458(0.75); C199(1.06)  LDD0669  [8]
 LDCM0353  AC87 HCT 116 C451(0.71); C458(0.71); C153(0.84); C199(1.03)  LDD0670  [8]
 LDCM0354  AC88 HCT 116 C153(0.61); C256(0.61); C255(0.79); C451(0.81)  LDD0671  [8]
 LDCM0355  AC89 HCT 116 C451(0.64); C458(0.64); C256(0.67); C255(0.87)  LDD0672  [8]
 LDCM0357  AC90 HCT 116 C451(0.65); C458(0.65); C153(0.69); C256(0.97)  LDD0674  [8]
 LDCM0358  AC91 HCT 116 C153(0.61); C255(0.73); C256(0.75); C451(0.84)  LDD0675  [8]
 LDCM0359  AC92 HCT 116 C256(0.61); C153(0.63); C451(0.67); C458(0.67)  LDD0676  [8]
 LDCM0360  AC93 HCT 116 C451(0.74); C458(0.74); C256(0.80); C153(0.84)  LDD0677  [8]
 LDCM0361  AC94 HCT 116 C153(0.67); C451(0.88); C458(0.88); C199(1.14)  LDD0678  [8]
 LDCM0362  AC95 HCT 116 C153(0.65); C256(0.66); C451(0.78); C458(0.78)  LDD0679  [8]
 LDCM0363  AC96 HCT 116 C451(0.78); C458(0.78); C153(0.81); C199(1.14)  LDD0680  [8]
 LDCM0364  AC97 HCT 116 C256(0.44); C451(0.51); C458(0.51); C255(0.65)  LDD0681  [8]
 LDCM0365  AC98 HCT 116 C451(0.17); C458(0.17); C255(0.28); C256(0.28)  LDD0682  [8]
 LDCM0366  AC99 HCT 116 C255(0.42); C256(0.42); C451(0.62); C458(0.62)  LDD0683  [8]
 LDCM0545  Acetamide MDA-MB-231 C153(0.95)  LDD2138  [5]
 LDCM0248  AKOS034007472 HCT 116 C153(1.09); C199(0.93); C255(1.83); C256(1.83)  LDD0565  [8]
 LDCM0356  AKOS034007680 HCT 116 C451(0.89); C458(0.89); C199(1.02); C153(1.10)  LDD0673  [8]
 LDCM0275  AKOS034007705 HCT 116 C451(0.18); C458(0.18); C255(0.81); C256(0.81)  LDD0592  [8]
 LDCM0020  ARS-1620 HCC44 C199(1.02); C451(0.87); C458(0.87); C153(0.87)  LDD0078  [8]
 LDCM0498  BS-3668 MDA-MB-231 C255(0.62); C153(1.04)  LDD2091  [5]
 LDCM0108  Chloroacetamide HeLa C153(0.00); C199(0.00)  LDD0222  [16]
 LDCM0367  CL1 HCT 116 C199(0.66); C153(0.87); C256(1.05); C255(1.16)  LDD0684  [8]
 LDCM0368  CL10 HCT 116 C199(0.71); C256(0.84); C255(0.95); C153(0.96)  LDD0685  [8]
 LDCM0369  CL100 HCT 116 C451(0.83); C458(0.83); C255(0.87); C256(0.89)  LDD0686  [8]
 LDCM0370  CL101 HCT 116 C451(0.66); C458(0.66); C199(0.99); C255(1.11)  LDD0687  [8]
 LDCM0371  CL102 HCT 116 C199(0.82); C451(1.00); C458(1.00); C153(1.07)  LDD0688  [8]
 LDCM0372  CL103 HCT 116 C199(0.88); C153(1.01); C451(1.32); C458(1.32)  LDD0689  [8]
 LDCM0373  CL104 HCT 116 C451(0.87); C458(0.87); C199(0.91); C153(1.02)  LDD0690  [8]
 LDCM0374  CL105 HCT 116 C255(0.61); C256(0.84); C451(0.87); C458(0.87)  LDD0691  [8]
 LDCM0375  CL106 HCT 116 C451(0.56); C458(0.56); C255(0.65); C199(0.66)  LDD0692  [8]
 LDCM0376  CL107 HCT 116 C255(0.56); C451(0.61); C458(0.61); C256(0.85)  LDD0693  [8]
 LDCM0377  CL108 HCT 116 C255(0.76); C451(0.81); C458(0.81); C256(0.83)  LDD0694  [8]
 LDCM0378  CL109 HCT 116 C255(0.50); C199(0.63); C256(0.75); C451(0.94)  LDD0695  [8]
 LDCM0379  CL11 HCT 116 C256(0.65); C255(0.76); C153(0.85); C199(0.95)  LDD0696  [8]
 LDCM0380  CL110 HCT 116 C199(0.57); C255(0.73); C451(0.74); C458(0.74)  LDD0697  [8]
 LDCM0381  CL111 HCT 116 C255(0.40); C451(0.71); C458(0.71); C199(0.79)  LDD0698  [8]
 LDCM0382  CL112 HCT 116 C153(0.86); C255(0.91); C256(0.91); C199(0.98)  LDD0699  [8]
 LDCM0383  CL113 HCT 116 C255(0.55); C256(0.55); C451(0.65); C458(0.65)  LDD0700  [8]
 LDCM0384  CL114 HCT 116 C255(0.50); C256(0.50); C451(0.64); C458(0.64)  LDD0701  [8]
 LDCM0385  CL115 HCT 116 C255(0.67); C256(0.67); C153(0.75); C451(0.77)  LDD0702  [8]
 LDCM0386  CL116 HCT 116 C153(0.91); C255(0.94); C256(0.94); C451(1.12)  LDD0703  [8]
 LDCM0387  CL117 HCT 116 C255(0.55); C256(0.80); C153(0.80); C451(1.24)  LDD0704  [8]
 LDCM0388  CL118 HCT 116 C255(0.78); C256(0.83); C153(0.95); C451(1.11)  LDD0705  [8]
 LDCM0389  CL119 HCT 116 C153(0.92); C256(0.93); C255(0.96); C451(1.05)  LDD0706  [8]
 LDCM0390  CL12 HCT 116 C256(0.77); C153(0.91); C255(0.93); C199(1.05)  LDD0707  [8]
 LDCM0391  CL120 HCT 116 C255(0.79); C451(0.93); C458(0.93); C256(0.97)  LDD0708  [8]
 LDCM0392  CL121 HCT 116 C255(0.92); C256(1.10); C153(1.10); C451(1.21)  LDD0709  [8]
 LDCM0393  CL122 HCT 116 C451(0.98); C458(0.98); C153(1.05); C255(1.09)  LDD0710  [8]
 LDCM0394  CL123 HCT 116 C255(0.71); C451(0.72); C458(0.72); C153(0.72)  LDD0711  [8]
 LDCM0395  CL124 HCT 116 C255(0.59); C451(0.63); C458(0.63); C153(0.68)  LDD0712  [8]
 LDCM0396  CL125 HCT 116 C451(0.92); C458(0.92); C256(0.95); C199(1.06)  LDD0713  [8]
 LDCM0397  CL126 HCT 116 C256(0.84); C451(0.87); C458(0.87); C153(0.92)  LDD0714  [8]
 LDCM0398  CL127 HCT 116 C256(0.83); C451(0.89); C458(0.89); C153(1.00)  LDD0715  [8]
 LDCM0399  CL128 HCT 116 C255(0.74); C256(0.80); C153(1.09); C451(1.37)  LDD0716  [8]
 LDCM0400  CL13 HCT 116 C199(0.86); C256(0.94); C153(0.99); C255(1.11)  LDD0717  [8]
 LDCM0401  CL14 HCT 116 C199(0.69); C153(0.82); C256(1.13); C255(1.25)  LDD0718  [8]
 LDCM0402  CL15 HCT 116 C153(0.92); C199(0.93); C256(1.08); C255(1.28)  LDD0719  [8]
 LDCM0403  CL16 HCT 116 C255(0.83); C256(0.84); C199(1.08); C153(1.14)  LDD0720  [8]
 LDCM0404  CL17 HCT 116 C256(0.86); C255(0.89); C153(0.93); C199(1.00)  LDD0721  [8]
 LDCM0405  CL18 HCT 116 C255(0.69); C256(0.88); C153(1.06); C199(1.42)  LDD0722  [8]
 LDCM0406  CL19 HCT 116 C255(0.87); C153(1.06); C256(1.11); C199(1.36)  LDD0723  [8]
 LDCM0407  CL2 HCT 116 C199(0.68); C153(0.99); C256(1.08); C255(1.13)  LDD0724  [8]
 LDCM0408  CL20 HCT 116 C255(0.82); C153(1.06); C256(1.11); C199(1.18)  LDD0725  [8]
 LDCM0409  CL21 HCT 116 C255(0.74); C153(0.92); C256(1.08); C199(1.51)  LDD0726  [8]
 LDCM0410  CL22 HCT 116 C255(0.56); C153(0.82); C256(0.98); C199(1.65)  LDD0727  [8]
 LDCM0411  CL23 HCT 116 C255(0.61); C256(0.89); C153(1.00); C199(1.21)  LDD0728  [8]
 LDCM0412  CL24 HCT 116 C255(0.57); C153(0.84); C256(0.84); C199(1.31)  LDD0729  [8]
 LDCM0413  CL25 HCT 116 C153(0.96); C199(1.20); C255(0.62); C256(0.83)  LDD0730  [8]
 LDCM0414  CL26 HCT 116 C153(0.96); C199(1.30); C255(0.67); C256(0.79)  LDD0731  [8]
 LDCM0415  CL27 HCT 116 C153(1.13); C199(1.22); C255(0.93); C256(1.09)  LDD0732  [8]
 LDCM0416  CL28 HCT 116 C153(1.02); C199(1.41); C255(0.67); C256(0.93)  LDD0733  [8]
 LDCM0417  CL29 HCT 116 C153(0.94); C199(1.42); C255(0.80); C256(1.17)  LDD0734  [8]
 LDCM0418  CL3 HCT 116 C153(0.97); C199(0.81); C255(1.14); C256(1.05)  LDD0735  [8]
 LDCM0419  CL30 HCT 116 C153(0.95); C199(1.07); C255(0.91); C256(0.97)  LDD0736  [8]
 LDCM0420  CL31 HCT 116 C153(0.96); C199(0.96); C255(1.09); C256(1.03)  LDD0737  [8]
 LDCM0421  CL32 HCT 116 C153(1.00); C199(1.14); C255(0.51); C256(0.83)  LDD0738  [8]
 LDCM0422  CL33 HCT 116 C153(0.90); C199(1.35); C255(0.66); C256(0.84)  LDD0739  [8]
 LDCM0423  CL34 HCT 116 C153(0.93); C199(1.09); C255(1.08); C256(1.35)  LDD0740  [8]
 LDCM0424  CL35 HCT 116 C153(0.94); C199(1.16); C255(0.88); C256(1.12)  LDD0741  [8]
 LDCM0425  CL36 HCT 116 C153(0.86); C199(1.05); C255(1.11); C256(0.84)  LDD0742  [8]
 LDCM0426  CL37 HCT 116 C153(0.99); C199(1.08); C255(0.98); C256(0.87)  LDD0743  [8]
 LDCM0428  CL39 HCT 116 C153(0.94); C199(1.07); C255(0.80); C256(0.84)  LDD0745  [8]
 LDCM0429  CL4 HCT 116 C153(0.98); C199(0.85); C255(1.16); C256(0.98)  LDD0746  [8]
 LDCM0430  CL40 HCT 116 C153(1.09); C199(1.20); C255(1.02); C256(0.74)  LDD0747  [8]
 LDCM0431  CL41 HCT 116 C153(0.90); C199(1.04); C255(0.73); C256(0.84)  LDD0748  [8]
 LDCM0432  CL42 HCT 116 C153(0.91); C199(1.32); C255(1.18); C256(0.84)  LDD0749  [8]
 LDCM0433  CL43 HCT 116 C153(0.85); C199(1.21); C255(0.83); C256(0.83)  LDD0750  [8]
 LDCM0434  CL44 HCT 116 C153(0.97); C199(1.13); C255(1.17); C256(0.91)  LDD0751  [8]
 LDCM0435  CL45 HCT 116 C153(1.01); C199(1.29); C255(0.97); C256(0.88)  LDD0752  [8]
 LDCM0436  CL46 HCT 116 C153(1.34); C199(1.16); C256(1.02); C451(0.95)  LDD0753  [8]
 LDCM0437  CL47 HCT 116 C153(1.39); C199(1.03); C256(1.03); C451(0.86)  LDD0754  [8]
 LDCM0438  CL48 HCT 116 C153(1.17); C199(1.06); C256(0.94); C451(1.25)  LDD0755  [8]
 LDCM0439  CL49 HCT 116 C153(1.12); C199(1.02); C256(0.77); C451(1.22)  LDD0756  [8]
 LDCM0440  CL5 HCT 116 C153(0.94); C199(0.71); C255(1.33); C256(1.13)  LDD0757  [8]
 LDCM0441  CL50 HCT 116 C153(1.24); C199(1.12); C256(0.78); C451(1.44)  LDD0758  [8]
 LDCM0442  CL51 HCT 116 C153(1.03); C199(0.93); C256(0.88); C451(1.25)  LDD0759  [8]
 LDCM0443  CL52 HCT 116 C153(0.92); C199(0.90); C256(0.72); C451(0.90)  LDD0760  [8]
 LDCM0444  CL53 HCT 116 C153(1.08); C199(1.38); C256(1.37); C451(1.90)  LDD0761  [8]
 LDCM0445  CL54 HCT 116 C153(0.97); C199(1.16); C256(0.90); C451(0.92)  LDD0762  [8]
 LDCM0446  CL55 HCT 116 C153(0.96); C199(1.00); C256(0.69); C451(1.28)  LDD0763  [8]
 LDCM0447  CL56 HCT 116 C153(1.07); C199(1.25); C256(0.92); C451(1.08)  LDD0764  [8]
 LDCM0448  CL57 HCT 116 C153(1.28); C199(1.12); C256(0.71); C451(1.48)  LDD0765  [8]
 LDCM0449  CL58 HCT 116 C153(0.96); C199(1.34); C256(0.80); C451(1.66)  LDD0766  [8]
 LDCM0450  CL59 HCT 116 C153(1.12); C199(1.03); C256(0.86); C451(1.26)  LDD0767  [8]
 LDCM0451  CL6 HCT 116 C153(0.95); C199(0.80); C255(1.38); C256(1.08)  LDD0768  [8]
 LDCM0452  CL60 HCT 116 C153(1.19); C199(1.26); C256(0.88); C451(1.27)  LDD0769  [8]
 LDCM0453  CL61 HCT 116 C199(1.01); C255(0.97); C256(1.04)  LDD0770  [8]
 LDCM0454  CL62 HCT 116 C199(1.07); C255(1.21); C256(1.14)  LDD0771  [8]
 LDCM0455  CL63 HCT 116 C199(1.00); C255(1.20); C256(1.15)  LDD0772  [8]
 LDCM0456  CL64 HCT 116 C199(1.11); C255(1.01); C256(1.07)  LDD0773  [8]
 LDCM0457  CL65 HCT 116 C199(1.05); C255(1.65); C256(1.32)  LDD0774  [8]
 LDCM0458  CL66 HCT 116 C199(1.23); C255(1.22); C256(1.15)  LDD0775  [8]
 LDCM0459  CL67 HCT 116 C199(1.05); C255(1.32); C256(1.26)  LDD0776  [8]
 LDCM0460  CL68 HCT 116 C199(1.07); C255(0.94); C256(1.12)  LDD0777  [8]
 LDCM0461  CL69 HCT 116 C199(1.04); C255(0.61); C256(0.83)  LDD0778  [8]
 LDCM0462  CL7 HCT 116 C153(0.99); C199(0.98); C255(1.18); C256(0.99)  LDD0779  [8]
 LDCM0463  CL70 HCT 116 C199(1.01); C255(0.89); C256(0.95)  LDD0780  [8]
 LDCM0464  CL71 HCT 116 C199(1.00); C255(0.95); C256(1.05)  LDD0781  [8]
 LDCM0465  CL72 HCT 116 C199(1.04); C255(0.79); C256(1.07)  LDD0782  [8]
 LDCM0466  CL73 HCT 116 C199(1.16); C255(0.88); C256(0.95)  LDD0783  [8]
 LDCM0467  CL74 HCT 116 C199(1.00); C255(1.10); C256(1.08)  LDD0784  [8]
 LDCM0469  CL76 HCT 116 C153(1.05); C199(1.07); C255(1.02); C256(1.38)  LDD0786  [8]
 LDCM0470  CL77 HCT 116 C153(0.95); C199(0.96); C255(0.75); C256(1.04)  LDD0787  [8]
 LDCM0471  CL78 HCT 116 C153(0.94); C199(1.01); C255(0.86); C256(1.65)  LDD0788  [8]
 LDCM0472  CL79 HCT 116 C153(1.17); C199(1.14); C255(1.04); C256(1.52)  LDD0789  [8]
 LDCM0473  CL8 HCT 116 C153(0.78); C199(0.94); C255(0.57); C256(0.66)  LDD0790  [8]
 LDCM0474  CL80 HCT 116 C153(1.02); C199(1.04); C255(0.96); C256(1.39)  LDD0791  [8]
 LDCM0475  CL81 HCT 116 C153(0.99); C199(1.08); C255(0.88); C256(1.90)  LDD0792  [8]
 LDCM0476  CL82 HCT 116 C153(1.03); C199(1.17); C255(0.79); C256(1.76)  LDD0793  [8]
 LDCM0477  CL83 HCT 116 C153(0.98); C199(1.18); C255(1.08); C256(1.74)  LDD0794  [8]
 LDCM0478  CL84 HCT 116 C153(1.07); C199(1.13); C255(0.91); C256(1.53)  LDD0795  [8]
 LDCM0479  CL85 HCT 116 C153(0.95); C199(1.10); C255(0.98); C256(1.36)  LDD0796  [8]
 LDCM0480  CL86 HCT 116 C153(0.90); C199(1.00); C255(0.99); C256(2.19)  LDD0797  [8]
 LDCM0481  CL87 HCT 116 C153(0.95); C199(1.08); C255(1.09); C256(1.87)  LDD0798  [8]
 LDCM0482  CL88 HCT 116 C153(0.96); C199(1.17); C255(0.99); C256(1.54)  LDD0799  [8]
 LDCM0483  CL89 HCT 116 C153(1.02); C199(1.28); C255(0.99); C256(1.39)  LDD0800  [8]
 LDCM0484  CL9 HCT 116 C153(0.95); C199(0.90); C255(0.88); C256(0.92)  LDD0801  [8]
 LDCM0485  CL90 HCT 116 C153(1.00); C199(0.94); C255(1.05); C256(1.79)  LDD0802  [8]
 LDCM0486  CL91 HCT 116 C153(1.01); C199(1.08); C255(0.70); C256(0.97)  LDD0803  [8]
 LDCM0487  CL92 HCT 116 C153(0.94); C199(0.90); C255(0.83); C256(0.87)  LDD0804  [8]
 LDCM0488  CL93 HCT 116 C153(1.00); C199(1.03); C255(0.81); C256(0.83)  LDD0805  [8]
 LDCM0489  CL94 HCT 116 C153(0.95); C199(1.15); C255(1.01); C256(0.90)  LDD0806  [8]
 LDCM0490  CL95 HCT 116 C153(0.95); C199(1.01); C255(0.81); C256(0.88)  LDD0807  [8]
 LDCM0491  CL96 HCT 116 C153(1.13); C199(1.09); C255(1.05); C256(1.10)  LDD0808  [8]
 LDCM0492  CL97 HCT 116 C153(0.92); C199(1.18); C255(1.18); C256(1.16)  LDD0809  [8]
 LDCM0493  CL98 HCT 116 C153(1.17); C199(1.20); C255(0.78); C256(0.95)  LDD0810  [8]
 LDCM0494  CL99 HCT 116 C153(1.19); C199(1.17); C255(0.82); C256(0.89)  LDD0811  [8]
 LDCM0495  E2913 HEK-293T C153(0.90); C199(0.97); C458(1.05); C451(0.85)  LDD1698  [20]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C153(0.92)  LDD1702  [5]
 LDCM0625  F8 Ramos C153(1.15)  LDD2187  [21]
 LDCM0572  Fragment10 Ramos C153(0.40)  LDD2189  [21]
 LDCM0573  Fragment11 Ramos C153(0.53)  LDD2190  [21]
 LDCM0574  Fragment12 Ramos C153(0.52)  LDD2191  [21]
 LDCM0576  Fragment14 Ramos C153(0.55)  LDD2193  [21]
 LDCM0579  Fragment20 Ramos C153(0.35)  LDD2194  [21]
 LDCM0580  Fragment21 Ramos C153(1.03)  LDD2195  [21]
 LDCM0582  Fragment23 Ramos C153(0.84)  LDD2196  [21]
 LDCM0578  Fragment27 Ramos C153(0.91)  LDD2197  [21]
 LDCM0586  Fragment28 Ramos C153(0.48)  LDD2198  [21]
 LDCM0588  Fragment30 Ramos C153(1.07)  LDD2199  [21]
 LDCM0590  Fragment32 Ramos C153(0.39)  LDD2201  [21]
 LDCM0468  Fragment33 HCT 116 C199(1.12); C255(0.99); C256(1.18)  LDD0785  [8]
 LDCM0596  Fragment38 Ramos C153(1.03)  LDD2203  [21]
 LDCM0566  Fragment4 Ramos C153(0.75)  LDD2184  [21]
 LDCM0427  Fragment51 HCT 116 C153(0.84); C199(1.24); C255(1.55); C256(1.18)  LDD0744  [8]
 LDCM0610  Fragment52 Ramos C153(0.98)  LDD2204  [21]
 LDCM0614  Fragment56 Ramos C153(1.16)  LDD2205  [21]
 LDCM0569  Fragment7 Ramos C153(0.71)  LDD2186  [21]
 LDCM0571  Fragment9 Ramos C153(0.40)  LDD2188  [21]
 LDCM0116  HHS-0101 DM93 Y245(0.91)  LDD0264  [6]
 LDCM0117  HHS-0201 DM93 Y245(1.38)  LDD0265  [6]
 LDCM0118  HHS-0301 DM93 Y245(1.61)  LDD0266  [6]
 LDCM0119  HHS-0401 DM93 Y245(1.74)  LDD0267  [6]
 LDCM0120  HHS-0701 DM93 Y245(1.37)  LDD0268  [6]
 LDCM0107  IAA HeLa N.A.  LDD0221  [16]
 LDCM0022  KB02 HCT 116 C199(1.65); C153(1.03); C256(0.99)  LDD0080  [8]
 LDCM0023  KB03 HCT 116 C199(1.39); C153(1.16); C256(0.99)  LDD0081  [8]
 LDCM0024  KB05 HCT 116 C199(1.47); C153(1.05); C256(0.94)  LDD0082  [8]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C153(1.08)  LDD2121  [5]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C153(1.01)  LDD2089  [5]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C153(1.09)  LDD2090  [5]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C256(1.06); C153(0.89)  LDD2092  [5]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C256(1.06); C255(0.98); C153(1.01)  LDD2093  [5]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C256(1.15); C153(1.02)  LDD2094  [5]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C255(0.85)  LDD2097  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C256(0.81)  LDD2098  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C256(0.80); C255(0.92)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C153(0.46)  LDD2100  [5]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C256(0.89)  LDD2101  [5]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C255(0.74)  LDD2104  [5]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C256(1.87); C153(0.97)  LDD2105  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C256(0.83); C255(0.79); C153(1.06); C199(1.57)  LDD2107  [5]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C256(0.66)  LDD2108  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C256(0.76); C255(0.65); C153(0.76); C199(0.95)  LDD2109  [5]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C256(0.81); C255(0.87); C153(1.14)  LDD2111  [5]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C255(0.91)  LDD2114  [5]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C255(0.52); C153(0.57)  LDD2115  [5]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C256(0.90); C255(0.92)  LDD2116  [5]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C256(0.69)  LDD2118  [5]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C256(2.06); C255(1.38)  LDD2119  [5]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C255(0.89)  LDD2120  [5]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C256(0.91)  LDD2122  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C256(0.72); C255(0.86); C153(0.98)  LDD2123  [5]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C256(0.80)  LDD2124  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C256(0.63); C255(0.69); C153(0.98); C199(1.80)  LDD2125  [5]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C256(0.64); C255(0.67); C153(1.12)  LDD2127  [5]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C255(0.93); C153(0.68)  LDD2128  [5]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C256(0.90); C255(0.85)  LDD2129  [5]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C255(0.57); C153(0.62)  LDD2133  [5]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C255(0.52)  LDD2134  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C256(0.85); C255(1.01)  LDD2135  [5]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C256(0.90); C255(1.04); C153(1.08); C199(2.08)  LDD2136  [5]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C256(0.86); C255(0.79); C153(1.15); C199(2.14)  LDD2137  [5]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C153(2.16)  LDD1700  [5]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C256(0.78); C255(0.96); C153(0.95)  LDD2140  [5]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C255(0.93)  LDD2143  [5]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C256(2.85); C255(2.36)  LDD2144  [5]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C255(0.66); C153(0.98)  LDD2146  [5]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C255(1.74)  LDD2147  [5]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C255(0.55)  LDD2148  [5]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C153(0.52)  LDD2150  [5]
 LDCM0099  Phenelzine MDA-MB-231 11.00  LDD0392  [1]
 LDCM0021  THZ1 HCT 116 C199(1.18)  LDD2173  [8]

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD028853
11 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
14 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
15 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
16 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD044402
21 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578