Details of the Probe

General Information of Probe

Probe ID
LDPC0507
Probe Name
C277
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 313.445
Lipid-water partition coefficient (xlogp) 3.7693
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C19H27N3O
Canonical SMILES
C#CCCC1(CCC(=O)N2CCC34CCC(CC23)C4(C)C)N=N1
InChI
InChI=1S/C19H27N3O/c1-4-5-8-19(20-21-19)10-7-16(23)22-12-11-18-9-6-14(13-15(18)22)17(18,2)3/h1,14-15H,5-13H2,2-3H3
InChIKey
ADYJJXLCPAKEAF-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

129 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 18.64  LDD1947 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 8.40  LDD1947 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 11.55  LDD1947 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 7.73  LDD1947 
Acid ceramidase (ASAH1) LDTP05905 25.46  LDD1947 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 8.22  LDD1947 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 9.32  LDD1947 
ADP-dependent glucokinase (ADPGK) LDTP11127 10.63  LDD1947 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 9.58  LDD1947 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 9.58  LDD1947 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 18.64  LDD1947 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 8.69  LDD1947 
Alpha-galactosidase A (GLA) LDTP02141 8.51  LDD1947 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 7.78  LDD1947 
Amidophosphoribosyltransferase (PPAT) LDTP05480 8.00  LDD1947 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 7.57  LDD1947 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 9.32  LDD1947 
Beta-galactosidase (GLB1) LDTP02837 8.94  LDD1947 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 9.65  LDD1947 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 8.40  LDD1947 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 15.78  LDD1947 
Calcyclin-binding protein (CACYBP) LDTP12163 25.63  LDD1947 
Calpain-1 catalytic subunit (CAPN1) LDTP02204 8.11  LDD1947 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 19.97  LDD1947 
Casein kinase I isoform alpha (CSNK1A1) LDTP04209 8.51  LDD1947 
Catechol O-methyltransferase (COMT) LDTP03145 9.92  LDD1947 
Ceramide glucosyltransferase (UGCG) LDTP06617 15.78  LDD1947 
Ceramide synthase 2 (CERS2) LDTP10329 22.16  LDD1947 
Choline kinase alpha (CHKA) LDTP03787 19.03  LDD1947 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 17.39  LDD1947 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 37.53  LDD1947 
Cytochrome b5 type B (CYB5B) LDTP00697 21.41  LDD1947 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 7.62  LDD1947 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 10.27  LDD1947 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 7.73  LDD1947 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 8.94  LDD1947 
Delta(24)-sterol reductase (DHCR24) LDTP06375 21.26  LDD1947 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 10.48  LDD1947 
Dihydrofolate reductase (DHFR) LDTP01769 36.00  LDD1947 
Dihydropyrimidinase-related protein 3 (DPYSL3) LDTP06079 7.46  LDD1947 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 8.17  LDD1947 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 16.91  LDD1947 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 8.88  LDD1947 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 22.32  LDD1947 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 11.88  LDD1947 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 7.94  LDD1947 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 12.38  LDD1947 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 8.22  LDD1947 
Epoxide hydrolase 1 (EPHX1) LDTP02175 9.38  LDD1947 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 23.92  LDD1947 
Gamma-glutamyl hydrolase (GGH) LDTP09886 7.89  LDD1947 
Glutathione S-transferase A4 (GSTA4) LDTP00575 21.26  LDD1947 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 10.34  LDD1947 
Helicase MOV-10 (MOV10) LDTP12233 10.41  LDD1947 
Heme oxygenase 1 (HMOX1) LDTP02359 23.26  LDD1947 
Heme oxygenase 2 (HMOX2) LDTP03540 27.10  LDD1947 
Hexokinase-2 (HK2) LDTP04531 7.62  LDD1947 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 10.13  LDD1947 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 8.51  LDD1947 
Holocytochrome c-type synthase (HCCS) LDTP04581 9.25  LDD1947 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 22.16  LDD1947 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 10.70  LDD1947 
Lathosterol oxidase (SC5D) LDTP01329 9.13  LDD1947 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 13.18  LDD1947 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 11.88  LDD1947 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 13.45  LDD1947 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 8.34  LDD1947 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 11.88  LDD1947 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 17.75  LDD1947 
Lysosomal acid phosphatase (ACP2) LDTP02539 7.62  LDD1947 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.00  LDD1947 
Lysosomal protective protein (CTSA) LDTP02505 15.14  LDD1947 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 12.38  LDD1947 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) LDTP00975 16.00  LDD1947 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 31.56  LDD1947 
Mitochondrial disaggregase (CLPB) LDTP11683 9.92  LDD1947 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 9.25  LDD1947 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 9.51  LDD1947 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 9.13  LDD1947 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 37.27  LDD1947 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 8.17  LDD1947 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 28.44  LDD1947 
NADPH--cytochrome P450 reductase (POR) LDTP02848 8.28  LDD1947 
Neurolysin, mitochondrial (NLN) LDTP11494 9.65  LDD1947 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 9.78  LDD1947 
Nucleoredoxin (NXN) LDTP07367 12.04  LDD1947 
Obg-like ATPase 1 (OLA1) LDTP12610 8.22  LDD1947 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 29.45  LDD1947 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 9.51  LDD1947 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 9.51  LDD1947 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 28.84  LDD1947 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 8.75  LDD1947 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 8.34  LDD1947 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 7.62  LDD1947 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 9.38  LDD1947 
Plasma membrane calcium-transporting ATPase 1 (ATP2B1) LDTP03024 9.92  LDD1947 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 8.57  LDD1947 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 28.05  LDD1947 
Presequence protease, mitochondrial (PITRM1) LDTP07003 20.53  LDD1947 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 7.89  LDD1947 
Prostaglandin reductase 3 (PTGR3) LDTP15422 18.51  LDD1947 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 11.24  LDD1947 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 18.25  LDD1947 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 7.57  LDD1947 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 11.55  LDD1947 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 16.11  LDD1947 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 8.75  LDD1947 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 33.36  LDD1947 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 13.36  LDD1947 
Ribonuclease H2 subunit A (RNASEH2A) LDTP01311 9.58  LDD1947 
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) LDTP03592 11.16  LDD1947 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 34.30  LDD1947 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 7.84  LDD1947 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 9.65  LDD1947 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 11.00  LDD1947 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 7.57  LDD1947 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 8.82  LDD1947 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 14.62  LDD1947 
Sulfotransferase 2A1 (SULT2A1) LDTP05493 50.21  LDD1947 
Thimet oligopeptidase (THOP1) LDTP04542 14.22  LDD1947 
TLC domain-containing protein 1 (TLCD1) LDTP10182 86.22  LDD1947 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 11.71  LDD1947 
tRNA wybutosine-synthesizing protein 4 (LCMT2) LDTP00942 9.58  LDD1947 
Ubiquitin carboxyl-terminal hydrolase 24 (USP24) LDTP13720 15.89  LDD1947 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 15.24  LDD1947 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 8.06  LDD1947 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 8.51  LDD1947 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 48.50  LDD1947 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 11.55  LDD1947 
------------------------------------------------------------------------------------
⏷ Show the Full List of 129 Enzyme
85 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 16.11  LDD1947 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 9.51  LDD1947 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 11.39  LDD1947 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 14.32  LDD1947 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 25.46  LDD1947 
BRI3-binding protein (BRI3BP) LDTP15648 22.01  LDD1947 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.52  LDD1947 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 17.39  LDD1947 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 8.82  LDD1947 
Derlin-1 (DERL1) LDTP11245 13.09  LDD1947 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 7.84  LDD1947 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 46.85  LDD1947 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 8.17  LDD1947 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 7.84  LDD1947 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 14.42  LDD1947 
Importin subunit alpha-5 (KPNA1) LDTP04502 8.63  LDD1947 
Importin-4 (IPO4) LDTP09515 11.79  LDD1947 
Importin-8 (IPO8) LDTP00630 7.73  LDD1947 
Integral membrane protein 2C (ITM2C) LDTP12451 8.82  LDD1947 
Intraflagellar transport protein 56 (IFT56) LDTP00010 8.57  LDD1947 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 7.62  LDD1947 
Lysosome membrane protein 2 (SCARB2) LDTP06034 9.38  LDD1947 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 13.18  LDD1947 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 7.73  LDD1947 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 11.88  LDD1947 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.93  LDD1947 
Metal transporter CNNM4 (CNNM4) LDTP07537 12.21  LDD1947 
Metaxin-1 (MTX1) LDTP05900 14.03  LDD1947 
MICOS complex subunit MIC26 (APOO) LDTP11250 9.65  LDD1947 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 7.78  LDD1947 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.94  LDD1947 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 24.25  LDD1947 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 39.67  LDD1947 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 11.63  LDD1947 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 50.21  LDD1947 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 34.06  LDD1947 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 19.97  LDD1947 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 11.55  LDD1947 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 12.04  LDD1947 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 16.80  LDD1947 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 7.67  LDD1947 
Nuclear pore complex protein Nup155 (NUP155) LDTP01295 10.34  LDD1947 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 7.52  LDD1947 
Nucleoporin NDC1 (NDC1) LDTP11213 14.72  LDD1947 
Nucleoporin NUP35 (NUP35) LDTP09204 11.79  LDD1947 
Oxysterol-binding protein-related protein 8 (OSBPL8) LDTP11531 7.62  LDD1947 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 8.82  LDD1947 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 7.94  LDD1947 
PRA1 family protein 2 (PRAF2) LDTP01060 14.42  LDD1947 
Prosaposin (PSAP) LDTP02215 10.06  LDD1947 
Protein FAM8A1 (FAM8A1) LDTP16190 7.94  LDD1947 
Protein GPR107 (GPR107) LDTP07236 13.18  LDD1947 
Protein GPR108 (GPR108) LDTP12383 15.78  LDD1947 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 9.92  LDD1947 
Protein tweety homolog 3 (TTYH3) LDTP11615 21.56  LDD1947 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 11.00  LDD1947 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 13.64  LDD1947 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 19.03  LDD1947 
Sideroflexin-4 (SFXN4) LDTP07531 8.88  LDD1947 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 24.93  LDD1947 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 11.31  LDD1947 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 38.05  LDD1947 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 8.63  LDD1947 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 17.88  LDD1947 
Solute carrier family 35 member F1 (SLC35F1) LDTP15000 9.99  LDD1947 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 15.35  LDD1947 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 8.34  LDD1947 
TBC1 domain family member 4 (TBC1D4) LDTP00958 9.25  LDD1947 
Tetraspanin-3 (TSPAN3) LDTP16813 22.78  LDD1947 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 14.42  LDD1947 
Translocation protein SEC63 homolog (SEC63) LDTP13243 16.11  LDD1947 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 24.42  LDD1947 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 11.71  LDD1947 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 17.88  LDD1947 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 9.19  LDD1947 
Transmembrane protein 126A (TMEM126A) LDTP15948 28.05  LDD1947 
Transmembrane protein 160 (TMEM160) LDTP20002 63.12  LDD1947 
Transmembrane protein 199 (TMEM199) LDTP08881 21.56  LDD1947 
Transmembrane protein 214 (TMEM214) LDTP07477 7.62  LDD1947 
Transportin-1 (TNPO1) LDTP09949 14.83  LDD1947 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 8.22  LDD1947 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 38.32  LDD1947 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 32.22  LDD1947 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 11.39  LDD1947 
Wolframin (WFS1) LDTP01380 10.06  LDD1947 
------------------------------------------------------------------------------------
⏷ Show the Full List of 85 Transporter and channel
2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 7.78  LDD1947 
Leukocyte surface antigen CD47 (CD47) LDTP05572 9.51  LDD1947 
------------------------------------------------------------------------------------
83 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 7.52  LDD1947 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 19.16  LDD1947 
Ankyrin repeat and SOCS box protein 6 (ASB6) LDTP12741 47.18  LDD1947 
Apolipoprotein L2 (APOL2) LDTP11076 27.28  LDD1947 
Armadillo repeat-containing protein 6 (ARMC6) LDTP15101 7.73  LDD1947 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 10.34  LDD1947 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 26.91  LDD1947 
Capping protein-inhibiting regulator of actin dynamics (CRACD) LDTP07839 14.62  LDD1947 
Clustered mitochondria protein homolog (CLUH) LDTP14486 15.45  LDD1947 
Costars family protein ABRACL (ABRACL) LDTP20008 80.45  LDD1947 
Crooked neck-like protein 1 (CRNKL1) LDTP11540 9.85  LDD1947 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 9.32  LDD1947 
DDB1- and CUL4-associated factor 7 (DCAF7) LDTP04947 14.22  LDD1947 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 13.55  LDD1947 
DNA repair protein XRCC1 (XRCC1) LDTP02973 14.22  LDD1947 
Dynein axonemal assembly factor 5 (DNAAF5) LDTP08387 11.00  LDD1947 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 64.89  LDD1947 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 27.67  LDD1947 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 26.72  LDD1947 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 14.22  LDD1947 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 8.17  LDD1947 
Ganglioside GM2 activator (GM2A) LDTP02927 11.71  LDD1947 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 8.11  LDD1947 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 17.03  LDD1947 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 9.25  LDD1947 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 10.20  LDD1947 
Heme-binding protein 2 (HEBP2) LDTP14186 8.34  LDD1947 
Hyaluronan mediated motility receptor (HMMR) LDTP01177 7.73  LDD1947 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 8.88  LDD1947 
Kinesin light chain 2 (KLC2) LDTP11695 7.41  LDD1947 
Large proline-rich protein BAG6 (BAG6) LDTP04094 9.45  LDD1947 
Large ribosomal subunit protein mL40 (MRPL40) LDTP12395 8.75  LDD1947 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 9.13  LDD1947 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 19.29  LDD1947 
Membralin (TMEM259) LDTP14939 18.25  LDD1947 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 10.63  LDD1947 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 10.56  LDD1947 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 8.63  LDD1947 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 8.69  LDD1947 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 39.12  LDD1947 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 14.12  LDD1947 
Neudesin (NENF) LDTP13630 9.85  LDD1947 
Neuferricin (CYB5D2) LDTP15623 8.22  LDD1947 
Nucleobindin-1 (NUCB1) LDTP05375 11.55  LDD1947 
Nucleobindin-2 (NUCB2) LDTP05160 56.89  LDD1947 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 11.39  LDD1947 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.94  LDD1947 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 7.41  LDD1947 
Optic atrophy 3 protein (OPA3) LDTP16006 8.57  LDD1947 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 19.03  LDD1947 
Peroxisomal membrane protein 11C (PEX11G) LDTP10381 14.72  LDD1947 
Phosducin-like protein 3 (PDCL3) LDTP11825 12.04  LDD1947 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 11.88  LDD1947 
Protein CEBPZOS (CEBPZOS) LDTP18883 31.34  LDD1947 
Protein CutA (CUTA) LDTP01075 7.36  LDD1947 
Protein FAM114A2 (FAM114A2) LDTP16080 15.45  LDD1947 
Protein FAM162A (FAM162A) LDTP10056 18.90  LDD1947 
Protein LYRIC (MTDH) LDTP08224 14.12  LDD1947 
Protein SERAC1 (SERAC1) LDTP10487 7.41  LDD1947 
Protein transport protein Sec16A (SEC16A) LDTP00512 8.28  LDD1947 
Protein unc-119 homolog B (UNC119B) LDTP00105 18.64  LDD1947 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 19.97  LDD1947 
RAD50-interacting protein 1 (RINT1) LDTP07476 11.39  LDD1947 
Reticulocalbin-2 (RCN2) LDTP06097 11.71  LDD1947 
Reticulon-3 (RTN3) LDTP01522 22.16  LDD1947 
Reticulon-4 (RTN4) LDTP12412 13.74  LDD1947 
RNA-binding protein FUS (FUS) LDTP03775 7.62  LDD1947 
RNA-binding protein FXR1 (FXR1) LDTP04395 7.73  LDD1947 
SEC14-like protein 2 (SEC14L2) LDTP01387 11.24  LDD1947 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.64  LDD1947 
Splicing factor 3B subunit 5 (SF3B5) LDTP11328 9.58  LDD1947 
Synaptogyrin-2 (SYNGR2) LDTP00859 13.74  LDD1947 
Syntaxin-18 (STX18) LDTP13086 34.06  LDD1947 
Tetraspanin-6 (TSPAN6) LDTP14458 35.75  LDD1947 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 12.73  LDD1947 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 10.48  LDD1947 
TraB domain-containing protein (TRABD) LDTP19963 14.03  LDD1947 
TRPM8 channel-associated factor 1 (TCAF1) LDTP14041 21.71  LDD1947 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 7.94  LDD1947 
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) LDTP12830 8.11  LDD1947 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 11.79  LDD1947 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 8.51  LDD1947 
Vimentin (VIM) LDTP02297 7.36  LDD1947 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1947 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587