Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0099
Competitor Name
Phenelzine
Synonyms
Phenelzine; 51-71-8; Phenethylhydrazine; 2-Phenylethylhydrazine; Nardil; Fenelzyne; Hydrazine, (2-phenylethyl)-; Fenelzyna; beta-Phenylethylhydrazine; Phenelzinum; Fenelzin; 2-Phenethylhydrazine; 1-Hydrazino-2-phenylethane; Phenethyl-hydrazine; Fenelzina; Phenalzine; (2-phenylethyl)hydrazine; Fenelzina [INN-Spanish]; Phenelzinum [INN-Latin]; HYDRAZINE, PHENETHYL-; W 1544-A; phenethyl hydrazine; W1544; EINECS 200-117-9; UNII-O408N561GF; BRN 0742354; HSDB 8127; O408N561GF; CHEMBL1089; CHEBI:8060; DTXSID2041094; 4-15-00-01269 (Beilstein Handbook Reference); Fenelzyna [Polish]; Fenelzyne [Polish]; Fenelzina (INN-Spanish); Phenelzinum (INN-Latin); Phenelzine [INN:BAN]; Phenylethylhydrazine; Phenelzine (BAN); 2 Phenethylhydrazine; beta Phenylethylhydrazine; (2-Phenyl-ethyl)-hydrazine; Nardil (Salt/Mix); Phenelzinum (Latin); Phenelzine Free Base; Spectrum_000851; PHENELZINE [MI]; PHENELZINE [INN]; Prestwick0_000170; Prestwick1_000170; Prestwick2_000170; Prestwick3_000170; Spectrum2_001009; Spectrum3_000677; Spectrum4_000475; Spectrum5_000990; Lopac-P-6777; 1-(2-phenethyl)hydrazine; PHENELZINE [VANDF]; CBChromo1_000176; .beta.-Phenylethylhydrazine; 1-(2-Phenylethyl)hydrazine; PHENELZINE [WHO-DD]; Lopac0_000971; SCHEMBL34335; BSPBio_000039; BSPBio_002373; KBioGR_000950; KBioGR_002265; KBioSS_001331; KBioSS_002266; DivK1c_000062; SPBio_001137; SPBio_001960; 1-(2-Phenylethyl)hydrazine #; BPBio1_000043; GTPL7266; DTXCID0021094; KBio1_000062; KBio2_001331; KBio2_002265; KBio2_003899; KBio2_004833; KBio2_006467; KBio2_007401; KBio3_001593; KBio3_002745; cMAP_000003; NINDS_000062; HMS3259L04; HY-B1018; BDBM50105417; MFCD00047825; AKOS000131105; CCG-205051; CS-4532; DB00780; MCULE-2911295500; NC00692; SDCCGSBI-0050944.P005; IDI1_000062; NCGC00015830-01; NCGC00015830-03; NCGC00015830-04; NCGC00015830-05; NCGC00015830-07; NCGC00015830-13; NCGC00162301-01; AS-77074; SBI-0050944.P004; DB-052010; AB00053520; NS00098766; EN300-58071; C07430; D08349; F74244; W-1544; AB00053520_12; A828737; Q1747559; BRD-K87024524-065-05-2; 14847-47-3
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 136.19
Lipid-water partition coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C8H12N2
IUPAC Name
2-phenylethylhydrazine
Canonical SMILES
C1=CC=C(C=C1)CCNN
InChI
InChI=1S/C8H12N2/c9-10-7-6-8-4-2-1-3-5-8/h1-5,10H,6-7,9H2
InChIKey
RMUCZJUITONUFY-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 3 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
Alkylaryl probe 3
 Probe Info  		1 mM Human normal cells (HEK-293T) [1]
Alkylaryl probe 1
 Probe Info  		1 mM Human normal cells (HEK-293T) [2]
Alkylaryl probe 2
 Probe Info  		1 mM Human normal cells (HEK-293T) [2]

Target(s) List of this Competitor

127 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 13.62  LDD0384 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 7.29  LDD0282 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 4.68  LDD0283 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 3.00  LDD0386 
Acid ceramidase (ASAH1) LDTP05905 3.82  LDD0384 
Acyl-CoA (8-3)-desaturase (FADS1) LDTP00968 5.08  LDD0282 
Acyl-CoA 6-desaturase (FADS2) LDTP01699 20.00  LDD0282 
Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 3.00  LDD0388 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 3.68  LDD0282 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 5.56  LDD0282 
Aldehyde dehydrogenase, mitochondrial (ALDH2) LDTP02074 11.81  LDD0282 
Alpha-galactosidase A (GLA) LDTP02141 3.00  LDD0386 
Alpha-ketoglutarate-dependent dioxygenase FTO (FTO) LDTP11595 5.00  LDD0390 
Alpha-N-acetylgalactosaminidase (NAGA) LDTP02883 3.00  LDD0392 
Amine oxidase [flavin-containing] A (MAOA) LDTP03109 20.00  LDD0282 
Amine oxidase [flavin-containing] B (MAOB) LDTP03384 20.00  LDD0282 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 20.00  LDD0384 
Aspartate aminotransferase, cytoplasmic (GOT1) LDTP02888 3.00  LDD0390 
Beta-galactosidase (GLB1) LDTP02837 3.00  LDD0386 
Beta-glucuronidase (GUSB) LDTP02260 4.00  LDD0388 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 3.00  LDD0388 
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (JMJD6) LDTP07492 3.00  LDD0390 
Biotinidase (BTD) LDTP04030 3.15  LDD0282 
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) LDTP04622 3.23  LDD0282 
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) LDTP00624 17.57  LDD0282 
BRCA1-associated protein (BRAP) LDTP08084 11.00  LDD0390 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 3.00  LDD0390 
Carboxypeptidase D (CPD) LDTP01372 15.00  LDD0392 
Cathepsin B (CTSB) LDTP02223 4.74  LDD0384 
Cathepsin D (CTSD) LDTP02198 10.30  LDD0282 
Cathepsin S (CTSS) LDTP03329 4.78  LDD0283 
Cathepsin Z (CTSZ) LDTP13147 5.98  LDD0283 
Cyclin-dependent kinase 11A (CDK11A) LDTP13752 12.36  LDD0382 
Cytochrome b5 type B (CYB5B) LDTP00697 3.00  LDD0392 
Cytosol aminopeptidase (LAP3) LDTP03455 3.00  LDD0388 
DBH-like monooxygenase protein 1 (MOXD1) LDTP07662 8.32  LDD0282 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 4.38  LDD0282 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 3.00  LDD0392 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 3.00  LDD0386 
DNA oxidative demethylase ALKBH2 (ALKBH2) LDTP07457 20.00  LDD0390 
Elongator complex protein 3 (ELP3) LDTP12110 3.00  LDD0390 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 4.00  LDD0392 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 4.00  LDD0392 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 7.78  LDD0384 
FAST kinase domain-containing protein 5, mitochondrial (FASTKD5) LDTP07979 3.00  LDD0386 
Ferritin heavy chain (FTH1) LDTP01974 11.92  LDD0384 
Ferrochelatase, mitochondrial (FECH) LDTP03198 4.00  LDD0390 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 3.00  LDD0386 
Fructose-bisphosphate aldolase C (ALDOC) LDTP02386 3.00  LDD0386 
Gamma-glutamyl hydrolase (GGH) LDTP09886 11.00  LDD0388 
Glutaredoxin-3 (GLRX3) LDTP01374 3.00  LDD0392 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 3.00  LDD0390 
Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5) LDTP18330 4.00  LDD0392 
Heme oxygenase 2 (HMOX2) LDTP03540 3.32  LDD0282 
Histone lysine demethylase PHF8 (PHF8) LDTP13703 15.00  LDD0390 
Holocytochrome c-type synthase (HCCS) LDTP04581 7.93  LDD0282 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 4.00  LDD0386 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 8.01  LDD0382 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 6.00  LDD0390 
Legumain (LGMN) LDTP10888 18.00  LDD0386 
Leucine carboxyl methyltransferase 1 (LCMT1) LDTP13337 3.00  LDD0386 
Lysine-specific demethylase 5C (KDM5C) LDTP03939 3.00  LDD0390 
Lysine-specific demethylase 5D (KDM5D) LDTP11440 3.00  LDD0390 
Lysine-specific histone demethylase 1A (KDM1A) LDTP00957 3.93  LDD0282 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 4.00  LDD0388 
Lysosomal alpha-glucosidase (GAA) LDTP02486 4.00  LDD0392 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 8.00  LDD0388 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 3.00  LDD0388 
Lysosomal protective protein (CTSA) LDTP02505 3.17  LDD0384 
Matrix metalloproteinase-14 (MMP14) LDTP04352 13.00  LDD0388 
Methanethiol oxidase (SELENBP1) LDTP05793 3.00  LDD0390 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 4.81  LDD0384 
Minor histocompatibility antigen H13 (HM13) LDTP09396 3.00  LDD0392 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 3.00  LDD0392 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 3.00  LDD0388 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 6.00  LDD0390 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 3.00  LDD0388 
Neurolysin, mitochondrial (NLN) LDTP11494 11.00  LDD0392 
Nucleic acid dioxygenase ALKBH1 (ALKBH1) LDTP05967 8.00  LDD0390 
Nucleoside diphosphate kinase 6 (NME6) LDTP01211 20.00  LDD0384 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 5.00  LDD0388 
Peroxidasin homolog (PXDN) LDTP09829 5.00  LDD0392 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 3.00  LDD0392 
Phytanoyl-CoA dioxygenase domain-containing protein 1 (PHYHD1) LDTP07065 3.00  LDD0390 
Pirin (PIR) LDTP00325 4.00  LDD0390 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 7.69  LDD0283 
Probable arginine--tRNA ligase, mitochondrial (RARS2) LDTP07092 4.00  LDD0386 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 3.00  LDD0386 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) LDTP05373 3.00  LDD0388 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) LDTP00285 3.00  LDD0390 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 3.00  LDD0388 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 3.00  LDD0390 
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) LDTP00645 3.00  LDD0390 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 14.64  LDD0282 
Protein phosphatase 1G (PPM1G) LDTP00616 20.00  LDD0382 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 3.00  LDD0392 
Putative transferase CAF17, mitochondrial (IBA57) LDTP07110 3.00  LDD0386 
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (PYROXD2) LDTP15408 20.00  LDD0392 
Ras-related protein Rab-11B (RAB11B) LDTP06501 4.00  LDD0392 
Ras-related protein Rab-13 (RAB13) LDTP04401 3.00  LDD0390 
Ras-related protein Rab-14 (RAB14) LDTP04901 3.00  LDD0392 
Ras-related protein Rab-5B (RAB5B) LDTP04893 3.00  LDD0392 
Ras-related protein Rab-5C (RAB5C) LDTP04398 3.00  LDD0392 
Retinal dehydrogenase 2 (ALDH1A2) LDTP01419 3.13  LDD0282 
Retinaldehyde dehydrogenase 3 (ALDH1A3) LDTP04134 7.47  LDD0282 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 4.00  LDD0388 
Ribonuclease T2 (RNASET2) LDTP00316 3.00  LDD0386 
Ribose-5-phosphate isomerase (RPIA) LDTP04236 3.00  LDD0386 
Ribosyldihydronicotinamide dehydrogenase [quinone] (NQO2) LDTP02824 5.03  LDD0282 
S-adenosylmethionine decarboxylase proenzyme (AMD1) LDTP02918 5.00  LDD0386 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 3.00  LDD0390 
Secernin-2 (SCRN2) LDTP15725 20.00  LDD0282 
Secernin-3 (SCRN3) LDTP17022 3.12  LDD0382 
Serine--tRNA ligase, mitochondrial (SARS2) LDTP12319 20.00  LDD0384 
Sialic acid synthase (NANS) LDTP12473 4.64  LDD0282 
Sialidase-1 (NEU1) LDTP10884 3.00  LDD0392 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 3.00  LDD0390 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 5.00  LDD0390 
Stearoyl-CoA desaturase (SCD) LDTP00344 20.00  LDD0282 
Sterol 26-hydroxylase, mitochondrial (CYP27A1) LDTP05348 3.00  LDD0392 
Sterol carrier protein 2 (SCP2) LDTP03163 20.00  LDD0282 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 20.00  LDD0382 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 3.00  LDD0390 
Trifunctional enzyme subunit beta, mitochondrial (HADHB) LDTP04671 3.03  LDD0384 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 5.41  LDD0384 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 3.00  LDD0392 
Xaa-Pro aminopeptidase 3 (XPNPEP3) LDTP12420 4.00  LDD0390 
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⏷ Show the Full List of 127 Enzyme
9 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 3.00  LDD0390 
Amyloid-beta precursor protein (APP) LDTP02071 4.00  LDD0388 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 4.00  LDD0392 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 3.93  LDD0382 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 3.21  LDD0384 
Prosaposin (PSAP) LDTP02215 4.04  LDD0384 
Syntenin-1 (SDCBP) LDTP00310 3.00  LDD0392 
Transferrin receptor protein 1 (TFRC) LDTP01969 3.00  LDD0388 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 3.00  LDD0388 
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⏷ Show the Full List of 9 Transporter and channel
1 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
HLA class I histocompatibility antigen, B alpha chain (HLA-B) LDTP01913 3.00  LDD0392 
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40 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
17S U2 SnRNP complex component HTATSF1 (HTATSF1) LDTP00849 20.00  LDD0382 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 7.00  LDD0388 
Calponin-2 (CNN2) LDTP10864 4.00  LDD0388 
Craniofacial development protein 1 (CFDP1) LDTP16193 20.00  LDD0382 
Cytochrome c oxidase copper chaperone (COX17) LDTP06030 3.15  LDD0282 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 5.00  LDD0388 
Density-regulated protein (DENR) LDTP00808 5.00  LDD0392 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 11.00  LDD0392 
Ferritin light chain (FTL) LDTP01973 3.00  LDD0392 
Galectin-3-binding protein (LGALS3BP) LDTP05558 3.00  LDD0388 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 20.00  LDD0382 
Golgin subfamily B member 1 (GOLGB1) LDTP06210 11.00  LDD0392 
GPALPP motifs-containing protein 1 (GPALPP1) LDTP17638 13.00  LDD0382 
Kelch-like ECH-associated protein 1 (KEAP1) LDTP06051 20.00  LDD0386 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 20.00  LDD0388 
Melanoma-associated antigen D2 (MAGED2) LDTP13657 6.00  LDD0388 
Microfibrillar-associated protein 1 (MFAP1) LDTP04668 20.00  LDD0382 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 5.27  LDD0384 
Nucleophosmin (NPM1) LDTP02164 3.36  LDD0384 
Plasminogen activator inhibitor 1 (SERPINE1) LDTP02085 3.00  LDD0388 
Probable RNA-binding protein EIF1AD (EIF1AD) LDTP09008 20.00  LDD0382 
Protein canopy homolog 3 (CNPY3) LDTP11176 5.00  LDD0392 
Protein IWS1 homolog (IWS1) LDTP10822 20.00  LDD0382 
Protein pelota homolog (PELO) LDTP11138 7.84  LDD0382 
Protein PRRC2C (PRRC2C) LDTP14085 3.00  LDD0392 
Protein SET (SET) LDTP05277 16.68  LDD0382 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 3.00  LDD0392 
Reticulon-4 (RTN4) LDTP12412 11.00  LDD0390 
RNA polymerase II-associated factor 1 homolog (PAF1) LDTP08965 4.14  LDD0382 
RNA polymerase-associated protein CTR9 homolog (CTR9) LDTP07563 3.55  LDD0382 
Scaffold attachment factor B2 (SAFB2) LDTP06054 11.59  LDD0384 
Small acidic protein (SMAP) LDTP19007 15.68  LDD0382 
Small ribosomal subunit protein mS35 (MRPS35) LDTP14788 20.00  LDD0392 
Spectrin beta chain, non-erythrocytic 2 (SPTBN2) LDTP00510 3.00  LDD0390 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 4.00  LDD0386 
Transcription elongation factor SPT5 (SUPT5H) LDTP00236 20.00  LDD0382 
WD repeat-containing protein 70 (WDR70) LDTP18478 20.00  LDD0382 
WW domain-binding protein 11 (WBP11) LDTP13920 20.00  LDD0382 
Zinc finger protein 185 (ZNF185) LDTP00580 20.00  LDD0388 
Zinc finger protein 318 (ZNF318) LDTP07223 3.00  LDD0390 
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⏷ Show the Full List of 40 Other

Full Information of The Labelling Profiles of This Competitor

Alkylaryl probe 1
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Interaction Atlas ID  LDD0386  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)
Interaction Atlas ID  LDD0388  Download The Altas

Alkylaryl probe 2
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Interaction Atlas ID  LDD0390  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)
Interaction Atlas ID  LDD0392  Download The Altas

Alkylaryl probe 3
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Interaction Atlas ID  LDD0282  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)
Interaction Atlas ID  LDD0283  Download The Altas
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Interaction Atlas ID  LDD0382  Download The Altas
  
Experiment 4 Reporting the Labelling Profiles of This Probe
REF [2]
Probe concentration 1 mM
Quantitative Method SILAC
Competitor Name Phenelzine
Competitor Concentration 10 mM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)
Interaction Atlas ID  LDD0384  Download The Altas

References

1 Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets. ACS Cent Sci. 2021 Sep 22;7(9):1524-1534. doi: 10.1021/acscentsci.1c00616. Epub 2021 Aug 19.
2 Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes. bioRxiv, 2020-06.