General Information of Experiment

Probe Name Alkylaryl probe 3  Probe Info 
Probe concentration 1 mM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Phenelzine  Competitor Info 
Competitor Concentration 10 mM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 12 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03109  Amine oxidase [flavin-containing] A (MAOA) 20.0
 LDTP03384  Amine oxidase [flavin-containing] B (MAOB) 20.0
 LDTP00624  Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) 20.0
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 9.6
 LDTP00957  Lysine-specific histone demethylase 1A (KDM1A) 9.1
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 7.7
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 6.8
 LDTP02074  Aldehyde dehydrogenase, mitochondrial (ALDH2) 6.1
 LDTP13147  Cathepsin Z (CTSZ) 6.0
 LDTP03329  Cathepsin S (CTSS) 4.8
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 4.7
 LDTP04581  Holocytochrome c-type synthase (HCCS) 2.6

References

1 Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets. ACS Cent Sci. 2021 Sep 22;7(9):1524-1534. doi: 10.1021/acscentsci.1c00616. Epub 2021 Aug 19.