General Information of Experiment

Probe Name Alkylaryl probe 1  Probe Info 
Probe concentration 1 mM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Phenelzine  Competitor Info 
Competitor Concentration 10 mM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 19 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10888  Legumain (LGMN) 18.0
 LDTP15725  Secernin-2 (SCRN2) 9.0
 LDTP17022  Secernin-3 (SCRN3) 6.0
 LDTP02918  S-adenosylmethionine decarboxylase proenzyme (AMD1) 5.0
 LDTP07763  Kynurenine--oxoglutarate transaminase 3 (KYAT3) 4.0
 LDTP07092  Probable arginine--tRNA ligase, mitochondrial (RARS2) 4.0
 LDTP18414  5'-nucleotidase domain-containing protein 2 (NT5DC2) 3.0
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 3.0
 LDTP02141  Alpha-galactosidase A (GLA) 3.0
 LDTP02837  Beta-galactosidase (GLB1) 3.0
 LDTP04572  Dipeptidyl peptidase 1 (CTSC) 3.0
 LDTP07979  FAST kinase domain-containing protein 5, mitochondrial (FASTKD5) 3.0
 LDTP02008  Fructose-bisphosphate aldolase A (ALDOA) 3.0
 LDTP02386  Fructose-bisphosphate aldolase C (ALDOC) 3.0
 LDTP13337  Leucine carboxyl methyltransferase 1 (LCMT1) 3.0
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 3.0
 LDTP07110  Putative transferase CAF17, mitochondrial (IBA57) 3.0
 LDTP00316  Ribonuclease T2 (RNASET2) 3.0
 LDTP04236  Ribose-5-phosphate isomerase (RPIA) 3.0
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02215  Prosaposin (PSAP) 3.0
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06051  Kelch-like ECH-associated protein 1 (KEAP1) 20.0
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 4.0

References

1 Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes. bioRxiv, 2020-06.