Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Alkylaryl probe 1 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 1 mM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | Phenelzine | Competitor Info | ||||
| Competitor Concentration | 10 mM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Breast | ||||
| Disease Model | Breast adenocarcinoma [ICD-11:2C60] | |||||
| Model Name | Human breast adenocarcinoma cells (MDA-MB-231) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP15725 | Secernin-2 (SCRN2) | 20.0 | ||||
| LDTP04352 | Matrix metalloproteinase-14 (MMP14) | 13.0 | ||||
| LDTP09886 | Gamma-glutamyl hydrolase (GGH) | 11.0 | ||||
| LDTP00338 | Lysosomal alpha-mannosidase (MAN2B1) | 8.0 | ||||
| LDTP02074 | Aldehyde dehydrogenase, mitochondrial (ALDH2) | 6.0 | ||||
| LDTP04572 | Dipeptidyl peptidase 1 (CTSC) | 6.0 | ||||
| LDTP10888 | Legumain (LGMN) | 6.0 | ||||
| LDTP17022 | Secernin-3 (SCRN3) | 6.0 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 5.0 | ||||
| LDTP18414 | 5'-nucleotidase domain-containing protein 2 (NT5DC2) | 4.0 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 4.0 | ||||
| LDTP02260 | Beta-glucuronidase (GUSB) | 4.0 | ||||
| LDTP04622 | Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) | 4.0 | ||||
| LDTP03329 | Cathepsin S (CTSS) | 4.0 | ||||
| LDTP03858 | Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) | 4.0 | ||||
| LDTP02505 | Lysosomal protective protein (CTSA) | 4.0 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 4.0 | ||||
| LDTP02918 | S-adenosylmethionine decarboxylase proenzyme (AMD1) | 4.0 | ||||
| LDTP04232 | 4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) | 3.0 | ||||
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 3.0 | ||||
| LDTP16274 | Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) | 3.0 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 3.0 | ||||
| LDTP02216 | Beta-hexosaminidase subunit beta (HEXB) | 3.0 | ||||
| LDTP02223 | Cathepsin B (CTSB) | 3.0 | ||||
| LDTP02198 | Cathepsin D (CTSD) | 3.0 | ||||
| LDTP13147 | Cathepsin Z (CTSZ) | 3.0 | ||||
| LDTP03455 | Cytosol aminopeptidase (LAP3) | 3.0 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 3.0 | ||||
| LDTP07651 | Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) | 3.0 | ||||
| LDTP02799 | N-acetylglucosamine-6-sulfatase (GNS) | 3.0 | ||||
| LDTP05373 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) | 3.0 | ||||
| LDTP06750 | Prolyl 3-hydroxylase 1 (P3H1) | 3.0 | ||||
| LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 3.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02071 | Amyloid-beta precursor protein (APP) | 4.0 | ||||
| LDTP02215 | Prosaposin (PSAP) | 3.0 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 3.0 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 3.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13606 | Mammalian ependymin-related protein 1 (EPDR1) | 20.0 | ||||
| LDTP00580 | Zinc finger protein 185 (ZNF185) | 20.0 | ||||
| LDTP05491 | Amyloid beta precursor like protein 2 (APLP2) | 7.0 | ||||
| LDTP13657 | Melanoma-associated antigen D2 (MAGED2) | 6.0 | ||||
| LDTP10613 | Dedicator of cytokinesis protein 7 (DOCK7) | 5.0 | ||||
| LDTP10864 | Calponin-2 (CNN2) | 4.0 | ||||
| LDTP05558 | Galectin-3-binding protein (LGALS3BP) | 3.0 | ||||
| LDTP06051 | Kelch-like ECH-associated protein 1 (KEAP1) | 3.0 | ||||
| LDTP02085 | Plasminogen activator inhibitor 1 (SERPINE1) | 3.0 | ||||