Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Alkylaryl probe 3 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 1 mM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | Phenelzine | Competitor Info | ||||
| Competitor Concentration | 10 mM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Breast | ||||
| Disease Model | Breast adenocarcinoma [ICD-11:2C60] | |||||
| Model Name | Human breast adenocarcinoma cells (MDA-MB-231) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03109 | Amine oxidase [flavin-containing] A (MAOA) | 20.0 | ||||
| LDTP03384 | Amine oxidase [flavin-containing] B (MAOB) | 20.0 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 20.0 | ||||
| LDTP00624 | Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) | 20.0 | ||||
| LDTP01211 | Nucleoside diphosphate kinase 6 (NME6) | 20.0 | ||||
| LDTP12319 | Serine--tRNA ligase, mitochondrial (SARS2) | 20.0 | ||||
| LDTP02329 | 3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) | 13.6 | ||||
| LDTP01974 | Ferritin heavy chain (FTH1) | 11.9 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 9.6 | ||||
| LDTP00957 | Lysine-specific histone demethylase 1A (KDM1A) | 9.1 | ||||
| LDTP01063 | Eukaryotic translation initiation factor 5B (EIF5B) | 7.8 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 7.7 | ||||
| LDTP01699 | Acyl-CoA 6-desaturase (FADS2) | 6.8 | ||||
| LDTP02074 | Aldehyde dehydrogenase, mitochondrial (ALDH2) | 6.1 | ||||
| LDTP13147 | Cathepsin Z (CTSZ) | 6.0 | ||||
| LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 5.4 | ||||
| LDTP12227 | Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) | 4.8 | ||||
| LDTP03329 | Cathepsin S (CTSS) | 4.8 | ||||
| LDTP02223 | Cathepsin B (CTSB) | 4.7 | ||||
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 4.7 | ||||
| LDTP02198 | Cathepsin D (CTSD) | 3.9 | ||||
| LDTP05724 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) | 3.8 | ||||
| LDTP05905 | Acid ceramidase (ASAH1) | 3.8 | ||||
| LDTP02505 | Lysosomal protective protein (CTSA) | 3.2 | ||||
| LDTP04671 | Trifunctional enzyme subunit beta, mitochondrial (HADHB) | 3.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02215 | Prosaposin (PSAP) | 4.0 | ||||
| LDTP04940 | NPC intracellular cholesterol transporter 2 (NPC2) | 3.2 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP06054 | Scaffold attachment factor B2 (SAFB2) | 11.6 | ||||
| LDTP13622 | NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) | 5.3 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | 3.4 | ||||