Details of the Probe

General Information of Probe

Probe ID
LDPC0569
Probe Name
C348
Synonyms
Z4225937802
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 342.4
Lipid-water partition coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C16H18N6OS
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-1-(4-ethyl-1,3-thiazol-2-yl)pyrazole-4-carboxamide
Canonical SMILES
CCC1=CSC(=N1)N2C=C(C=N2)C(=O)NCCC3(N=N3)CCC#C
InChI
InChI=1S/C16H18N6OS/c1-3-5-6-16(20-21-16)7-8-17-14(23)12-9-18-22(10-12)15-19-13(4-2)11-24-15/h1,9-11H,4-8H2,2H3,(H,17,23)
InChIKey
YLOXUCSQGVPSIA-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

122 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 14.52  LDD2009 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 21.56  LDD2009 
Acid ceramidase (ASAH1) LDTP05905 15.89  LDD2009 
Adenosine deaminase (ADA) LDTP01803 10.56  LDD2009 
Adenosine kinase (ADK) LDTP04689 99.73  LDD2009 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 13.36  LDD2009 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 14.52  LDD2009 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 11.24  LDD2009 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 22.16  LDD2009 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 65.34  LDD2009 
Atlastin-2 (ATL2) LDTP09251 10.27  LDD2009 
ATP-dependent RNA helicase DDX50 (DDX50) LDTP11051 12.82  LDD2009 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 14.52  LDD2009 
Beta-galactosidase (GLB1) LDTP02837 12.47  LDD2009 
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) LDTP02706 10.06  LDD2009 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 20.68  LDD2009 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 17.75  LDD2009 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 25.63  LDD2009 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 10.85  LDD2009 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 14.83  LDD2009 
Cartilage-associated protein (CRTAP) LDTP01300 10.70  LDD2009 
Catechol O-methyltransferase (COMT) LDTP03145 26.35  LDD2009 
Ceramide synthase 1 (CERS1) LDTP03394 10.27  LDD2009 
Ceramide synthase 2 (CERS2) LDTP10329 26.91  LDD2009 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 13.55  LDD2009 
COP9 signalosome complex subunit 6 (COPS6) LDTP07966 20.97  LDD2009 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 20.11  LDD2009 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 28.25  LDD2009 
Cytochrome b5 type B (CYB5B) LDTP00697 57.28  LDD2009 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 18.38  LDD2009 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 22.01  LDD2009 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 15.67  LDD2009 
DCN1-like protein 4 (DCUN1D4) LDTP09799 20.82  LDD2009 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 10.06  LDD2009 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 14.83  LDD2009 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 15.45  LDD2009 
Delta(24)-sterol reductase (DHCR24) LDTP06375 12.47  LDD2009 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 9.92  LDD2009 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 20.97  LDD2009 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 28.05  LDD2009 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 10.48  LDD2009 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 11.79  LDD2009 
E3 ubiquitin-protein ligase synoviolin (SYVN1) LDTP08203 10.41  LDD2009 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 16.45  LDD2009 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 11.96  LDD2009 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 14.32  LDD2009 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 24.08  LDD2009 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 25.99  LDD2009 
Ephrin type-A receptor 7 (EPHA7) LDTP06370 20.11  LDD2009 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 10.93  LDD2009 
Fumarylacetoacetase (FAH) LDTP02868 12.04  LDD2009 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 11.96  LDD2009 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 14.83  LDD2009 
Heme A synthase COX15 (COX15) LDTP07931 10.70  LDD2009 
Heme oxygenase 1 (HMOX1) LDTP02359 31.12  LDD2009 
Heme oxygenase 2 (HMOX2) LDTP03540 65.34  LDD2009 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 32.22  LDD2009 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 21.56  LDD2009 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 10.41  LDD2009 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 66.72  LDD2009 
Lathosterol oxidase (SC5D) LDTP01329 11.08  LDD2009 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 18.64  LDD2009 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 11.00  LDD2009 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 56.89  LDD2009 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 14.62  LDD2009 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 11.63  LDD2009 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 21.86  LDD2009 
Lysosomal protective protein (CTSA) LDTP02505 13.93  LDD2009 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 26.54  LDD2009 
Minor histocompatibility antigen H13 (HM13) LDTP09396 12.91  LDD2009 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 10.56  LDD2009 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 13.64  LDD2009 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 19.84  LDD2009 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 22.01  LDD2009 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 10.93  LDD2009 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 15.56  LDD2009 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 12.73  LDD2009 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 17.03  LDD2009 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 61.39  LDD2009 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 25.46  LDD2009 
NADPH--cytochrome P450 reductase (POR) LDTP02848 10.34  LDD2009 
Nardilysin (NRDC) LDTP00886 9.99  LDD2009 
Neurolysin, mitochondrial (NLN) LDTP11494 15.56  LDD2009 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 11.39  LDD2009 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 33.59  LDD2009 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 28.64  LDD2009 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 31.34  LDD2009 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 22.47  LDD2009 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 10.27  LDD2009 
Phosphatidylserine lipase ABHD16A (ABHD16A) LDTP01704 10.34  LDD2009 
Phospholipase A2 group XV (PLA2G15) LDTP09088 19.56  LDD2009 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 11.31  LDD2009 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 12.64  LDD2009 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 28.25  LDD2009 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 29.65  LDD2009 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 12.13  LDD2009 
Presequence protease, mitochondrial (PITRM1) LDTP07003 19.29  LDD2009 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 11.47  LDD2009 
Prostaglandin reductase 3 (PTGR3) LDTP15422 42.81  LDD2009 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 20.82  LDD2009 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 14.22  LDD2009 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 12.04  LDD2009 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 22.78  LDD2009 
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) LDTP04925 13.74  LDD2009 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 21.56  LDD2009 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 16.45  LDD2009 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 9.92  LDD2009 
Receptor-type tyrosine-protein phosphatase F (PTPRF) LDTP02499 10.27  LDD2009 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 13.74  LDD2009 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.56  LDD2009 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 10.78  LDD2009 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 10.27  LDD2009 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 12.13  LDD2009 
Septin-2 (SEPTIN2) LDTP06279 11.16  LDD2009 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 27.67  LDD2009 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 15.56  LDD2009 
Squalene monooxygenase (SQLE) LDTP06142 13.45  LDD2009 
Squalene synthase (FDFT1) LDTP03842 27.67  LDD2009 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 14.32  LDD2009 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 12.64  LDD2009 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 32.00  LDD2009 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 20.68  LDD2009 
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⏷ Show the Full List of 122 Enzyme
76 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 27.28  LDD2009 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 24.42  LDD2009 
Anoctamin-10 (ANO10) LDTP12704 10.93  LDD2009 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 13.74  LDD2009 
ATP synthase subunit a (MT-ATP6) LDTP01804 51.27  LDD2009 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 12.64  LDD2009 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 17.15  LDD2009 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 10.06  LDD2009 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 13.55  LDD2009 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 22.94  LDD2009 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 17.51  LDD2009 
Derlin-1 (DERL1) LDTP11245 28.05  LDD2009 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 61.82  LDD2009 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 30.48  LDD2009 
Exportin-T (XPOT) LDTP00810 16.68  LDD2009 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 10.85  LDD2009 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 13.74  LDD2009 
Integral membrane protein 2C (ITM2C) LDTP12451 11.79  LDD2009 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 14.83  LDD2009 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 14.03  LDD2009 
Lysosome membrane protein 2 (SCARB2) LDTP06034 31.12  LDD2009 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 15.56  LDD2009 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 23.75  LDD2009 
Metaxin-1 (MTX1) LDTP05900 12.47  LDD2009 
Metaxin-2 (MTX2) LDTP01217 10.34  LDD2009 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 15.89  LDD2009 
MICOS complex subunit MIC26 (APOO) LDTP11250 15.89  LDD2009 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 28.64  LDD2009 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 14.03  LDD2009 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 16.56  LDD2009 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 17.03  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 64.00  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 37.01  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 30.91  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 11.79  LDD2009 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 12.13  LDD2009 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 15.56  LDD2009 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 9.85  LDD2009 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 40.79  LDD2009 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 21.86  LDD2009 
Nucleoporin NDC1 (NDC1) LDTP11213 15.56  LDD2009 
Nucleoporin NUP188 (NUP188) LDTP07064 9.92  LDD2009 
Nucleoporin Nup37 (NUP37) LDTP09203 10.06  LDD2009 
PRA1 family protein 2 (PRAF2) LDTP01060 11.39  LDD2009 
Protein GPR107 (GPR107) LDTP07236 23.59  LDD2009 
Protein GPR108 (GPR108) LDTP12383 11.55  LDD2009 
Protein tweety homolog 3 (TTYH3) LDTP11615 45.57  LDD2009 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 20.68  LDD2009 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 39.67  LDD2009 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 13.83  LDD2009 
Reticulon-1 (RTN1) LDTP06633 27.10  LDD2009 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 16.45  LDD2009 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 10.48  LDD2009 
Secretory carrier-associated membrane protein 4 (SCAMP4) LDTP09987 10.93  LDD2009 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 22.78  LDD2009 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 22.32  LDD2009 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 12.21  LDD2009 
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) LDTP12809 17.15  LDD2009 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 43.11  LDD2009 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 12.82  LDD2009 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 17.27  LDD2009 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 12.91  LDD2009 
Stomatin (STOM) LDTP03380 9.92  LDD2009 
SUN domain-containing protein 2 (SUN2) LDTP13256 10.34  LDD2009 
Syntaxin-6 (STX6) LDTP00857 19.70  LDD2009 
Tetraspanin-3 (TSPAN3) LDTP16813 30.27  LDD2009 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 13.00  LDD2009 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 47.84  LDD2009 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 14.83  LDD2009 
Transmembrane protein 126A (TMEM126A) LDTP15948 33.13  LDD2009 
Transmembrane protein 199 (TMEM199) LDTP08881 29.45  LDD2009 
Transmembrane protein 230 (TMEM230) LDTP10065 14.72  LDD2009 
Transmembrane protein 87A (TMEM87A) LDTP15481 37.27  LDD2009 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 66.26  LDD2009 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 57.28  LDD2009 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 52.71  LDD2009 
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⏷ Show the Full List of 76 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 15.03  LDD2009 
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3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 13.36  LDD2009 
IgG receptor FcRn large subunit p51 (FCGRT) LDTP04720 17.39  LDD2009 
Leukocyte surface antigen CD47 (CD47) LDTP05572 11.08  LDD2009 
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103 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 10.27  LDD2009 
Alpha-internexin (INA) LDTP06527 10.63  LDD2009 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 21.26  LDD2009 
Apolipoprotein L2 (APOL2) LDTP11076 66.26  LDD2009 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 9.92  LDD2009 
Calumenin (CALU) LDTP00887 15.78  LDD2009 
Centrosomal protein 43 (CEP43) LDTP01652 12.21  LDD2009 
Clustered mitochondria protein homolog (CLUH) LDTP14486 27.47  LDD2009 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 11.39  LDD2009 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 12.30  LDD2009 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 10.13  LDD2009 
Craniofacial development protein 1 (CFDP1) LDTP16193 13.93  LDD2009 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 30.70  LDD2009 
DBIRD complex subunit ZNF326 (ZNF326) LDTP06952 16.34  LDD2009 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 10.85  LDD2009 
Dynactin subunit 3 (DCTN3) LDTP01359 21.56  LDD2009 
Emerin (EMD) LDTP04356 12.82  LDD2009 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 15.56  LDD2009 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 51.98  LDD2009 
Ganglioside GM2 activator (GM2A) LDTP02927 12.73  LDD2009 
GH3 domain-containing protein (GHDC) LDTP08795 11.00  LDD2009 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 23.59  LDD2009 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 21.41  LDD2009 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 14.52  LDD2009 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 11.31  LDD2009 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 17.63  LDD2009 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 10.48  LDD2009 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 13.18  LDD2009 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 10.13  LDD2009 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 10.93  LDD2009 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 10.63  LDD2009 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 10.41  LDD2009 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 10.34  LDD2009 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 15.14  LDD2009 
Kinetochore protein Spc24 (SPC24) LDTP09069 12.21  LDD2009 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 11.24  LDD2009 
Large proline-rich protein BAG6 (BAG6) LDTP04094 11.47  LDD2009 
Large ribosomal subunit protein mL40 (MRPL40) LDTP12395 16.22  LDD2009 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 36.00  LDD2009 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 23.10  LDD2009 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 10.41  LDD2009 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 18.38  LDD2009 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 37.27  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 11.47  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 12.91  LDD2009 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 13.09  LDD2009 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2009 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 21.71  LDD2009 
Myosin light chain 6B (MYL6B) LDTP02736 17.15  LDD2009 
NEDD8 ultimate buster 1 (NUB1) LDTP14104 11.31  LDD2009 
Negative elongation factor C/D (NELFCD) LDTP08594 9.85  LDD2009 
Neudesin (NENF) LDTP13630 11.71  LDD2009 
Neuferricin (CYB5D2) LDTP15623 12.91  LDD2009 
Nucleobindin-2 (NUCB2) LDTP05160 22.01  LDD2009 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 10.34  LDD2009 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 13.45  LDD2009 
Nurim (NRM) LDTP08606 16.45  LDD2009 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 11.96  LDD2009 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 10.27  LDD2009 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 10.34  LDD2009 
Prelamin-A/C (LMNA) LDTP01932 18.77  LDD2009 
Programmed cell death protein 5 (PDCD5) LDTP00417 11.47  LDD2009 
Proline-rich protein PRCC (PRCC) LDTP09850 13.18  LDD2009 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 14.72  LDD2009 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 11.39  LDD2009 
Protein CutA (CUTA) LDTP01075 14.12  LDD2009 
Protein FAM114A2 (FAM114A2) LDTP16080 11.96  LDD2009 
Protein FAM162A (FAM162A) LDTP10056 26.17  LDD2009 
Protein FAM177A1 (FAM177A1) LDTP15398 16.11  LDD2009 
Protein FAM3C (FAM3C) LDTP09773 12.73  LDD2009 
Protein jagunal homolog 1 (JAGN1) LDTP08904 12.30  LDD2009 
Protein LYRIC (MTDH) LDTP08224 13.09  LDD2009 
Protein SET (SET) LDTP05277 11.71  LDD2009 
Protein unc-119 homolog A (UNC119) LDTP05868 21.26  LDD2009 
Protein UXT (UXT) LDTP13125 13.45  LDD2009 
Protein YIF1A (YIF1A) LDTP01494 9.92  LDD2009 
Reticulocalbin-2 (RCN2) LDTP06097 31.56  LDD2009 
Reticulon-2 (RTN2) LDTP01167 22.63  LDD2009 
Reticulon-3 (RTN3) LDTP01522 18.00  LDD2009 
Reticulon-4 (RTN4) LDTP12412 30.70  LDD2009 
Retinol-binding protein 1 (RBP1) LDTP02345 22.78  LDD2009 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 11.71  LDD2009 
RNA-binding protein 14 (RBM14) LDTP10684 10.27  LDD2009 
RNA-binding protein 3 (RBM3) LDTP05226 12.30  LDD2009 
RNA-binding protein EWS (EWSR1) LDTP05318 11.24  LDD2009 
RNA-binding protein FUS (FUS) LDTP03775 17.03  LDD2009 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 16.11  LDD2009 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 13.93  LDD2009 
Synaptogyrin-2 (SYNGR2) LDTP00859 12.47  LDD2009 
Syntaxin-10 (STX10) LDTP00986 32.00  LDD2009 
Syntaxin-18 (STX18) LDTP13086 16.91  LDD2009 
Syntaxin-7 (STX7) LDTP00632 14.83  LDD2009 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 10.06  LDD2009 
Tetraspanin-6 (TSPAN6) LDTP14458 57.68  LDD2009 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 13.00  LDD2009 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 18.77  LDD2009 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 10.85  LDD2009 
TraB domain-containing protein (TRABD) LDTP19963 16.11  LDD2009 
Transmembrane protein 209 (TMEM209) LDTP18272 21.86  LDD2009 
U3 small nucleolar RNA-associated protein 25 homolog (UTP25) LDTP07315 15.14  LDD2009 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 48.50  LDD2009 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 11.31  LDD2009 
Vimentin (VIM) LDTP02297 12.55  LDD2009 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2009 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587