Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Alkylaryl probe 3 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 1 mM | |||||
| Criteria | Quantification: Probe vs DMSO | |||||
| Quantitative Method |
SILAC
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10828 | 2-aminoethanethiol dioxygenase (ADO) | 20.0 | ||||
| LDTP02329 | 3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) | 20.0 | ||||
| LDTP10984 | 5-demethoxyubiquinone hydroxylase, mitochondrial (COQ7) | 20.0 | ||||
| LDTP11268 | Acireductone dioxygenase (ADI1) | 20.0 | ||||
| LDTP01699 | Acyl-CoA 6-desaturase (FADS2) | 20.0 | ||||
| LDTP01767 | Aldehyde dehydrogenase 1A1 (ALDH1A1) | 20.0 | ||||
| LDTP04437 | Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) | 20.0 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 20.0 | ||||
| LDTP02074 | Aldehyde dehydrogenase, mitochondrial (ALDH2) | 20.0 | ||||
| LDTP03109 | Amine oxidase [flavin-containing] A (MAOA) | 20.0 | ||||
| LDTP03384 | Amine oxidase [flavin-containing] B (MAOB) | 20.0 | ||||
| LDTP04030 | Biotinidase (BTD) | 20.0 | ||||
| LDTP00624 | Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) | 20.0 | ||||
| LDTP07662 | DBH-like monooxygenase protein 1 (MOXD1) | 20.0 | ||||
| LDTP12803 | Dipeptidyl peptidase 3 (DPP3) | 20.0 | ||||
| LDTP00464 | Glutathione S-transferase 3, mitochondrial (MGST3) | 20.0 | ||||
| LDTP04581 | Holocytochrome c-type synthase (HCCS) | 20.0 | ||||
| LDTP00957 | Lysine-specific histone demethylase 1A (KDM1A) | 20.0 | ||||
| LDTP11494 | Neurolysin, mitochondrial (NLN) | 20.0 | ||||
| LDTP03816 | Oxidized purine nucleoside triphosphate hydrolase (NUDT1) | 20.0 | ||||
| LDTP07065 | Phytanoyl-CoA dioxygenase domain-containing protein 1 (PHYHD1) | 20.0 | ||||
| LDTP12040 | Prostaglandin E synthase 2 (PTGES2) | 20.0 | ||||
| LDTP01419 | Retinal dehydrogenase 2 (ALDH1A2) | 20.0 | ||||
| LDTP04134 | Retinaldehyde dehydrogenase 3 (ALDH1A3) | 20.0 | ||||
| LDTP07989 | Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) | 20.0 | ||||
| LDTP02824 | Ribosyldihydronicotinamide dehydrogenase [quinone] (NQO2) | 20.0 | ||||
| LDTP15725 | Secernin-2 (SCRN2) | 20.0 | ||||
| LDTP12473 | Sialic acid synthase (NANS) | 20.0 | ||||
| LDTP00344 | Stearoyl-CoA desaturase (SCD) | 20.0 | ||||
| LDTP03163 | Sterol carrier protein 2 (SCP2) | 20.0 | ||||
| LDTP10887 | Synaptic vesicle membrane protein VAT-1 homolog (VAT1) | 20.0 | ||||
| LDTP02074 | Aldehyde dehydrogenase, mitochondrial (ALDH2) | 19.7 | ||||
| LDTP07662 | DBH-like monooxygenase protein 1 (MOXD1) | 19.6 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 18.2 | ||||
| LDTP11054 | Zinc phosphodiesterase ELAC protein 2 (ELAC2) | 17.6 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 16.4 | ||||
| LDTP04232 | 4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) | 16.2 | ||||
| LDTP11321 | Acetyl-CoA acetyltransferase, cytosolic (ACAT2) | 15.7 | ||||
| LDTP10215 | Carboxymethylenebutenolidase homolog (CMBL) | 15.3 | ||||
| LDTP12679 | Trimethyllysine dioxygenase, mitochondrial (TMLHE) | 15.1 | ||||
| LDTP12444 | Xaa-Pro aminopeptidase 1 (XPNPEP1) | 14.1 | ||||
| LDTP05434 | Lactoylglutathione lyase (GLO1) | 13.5 | ||||
| LDTP02679 | Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) | 12.9 | ||||
| LDTP06910 | Endoribonuclease LACTB2 (LACTB2) | 12.7 | ||||
| LDTP00968 | Acyl-CoA (8-3)-desaturase (FADS1) | 12.0 | ||||
| LDTP01707 | Thioredoxin domain-containing protein 12 (TXNDC12) | 11.7 | ||||
| LDTP04622 | Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) | 11.2 | ||||
| LDTP10981 | Mitochondrial intermediate peptidase (MIPEP) | 10.0 | ||||
| LDTP02198 | Cathepsin D (CTSD) | 9.7 | ||||
| LDTP00968 | Acyl-CoA (8-3)-desaturase (FADS1) | 8.6 | ||||
| LDTP07110 | Putative transferase CAF17, mitochondrial (IBA57) | 8.3 | ||||
| LDTP02765 | Aldo-keto reductase family 1 member B1 (AKR1B1) | 7.1 | ||||
| LDTP05992 | Bleomycin hydrolase (BLMH) | 7.1 | ||||
| LDTP04438 | Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) | 6.6 | ||||
| LDTP05724 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) | 6.2 | ||||
| LDTP10878 | Parkinson disease protein 7 (PARK7) | 6.2 | ||||
| LDTP02333 | Glutathione S-transferase P (GSTP1) | 5.8 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02256 | Amino acid transporter heavy chain SLC3A2 (SLC3A2) | 20.0 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 20.0 | ||||
| LDTP13824 | Voltage-dependent anion-selective channel protein 3 (VDAC3) | 7.3 | ||||
| LDTP14235 | Mitochondrial carrier homolog 2 (MTCH2) | 6.9 | ||||
| LDTP05238 | Solute carrier family 25 member 3 (SLC25A3) | 6.7 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 6.4 | ||||
| LDTP05231 | Cytochrome c (CYCS) | 5.7 | ||||
| LDTP03559 | High affinity cationic amino acid transporter 1 (SLC7A1) | 5.7 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP09187 | F-box only protein 22 (FBXO22) | 20.0 | ||||
| LDTP06030 | Cytochrome c oxidase copper chaperone (COX17) | 12.4 | ||||
| LDTP16938 | Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial (GATD3) | 7.8 | ||||
| LDTP13630 | Neudesin (NENF) | 6.0 | ||||