Details of the Probe

General Information of Probe

Probe ID
LDPC0376
Probe Name
C134
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 340.21
Lipid-water partition coefficient (xlogp) 3.1086
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C15H15Cl2N3O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])N([H])C(=O)C([H])(O[H])c2c([H])c(Cl)c([H])c(Cl)c2[H])N=N1
InChI
InChI=1S/C15H15Cl2N3O2/c1-2-3-4-15(19-20-15)5-6-18-14(22)13(21)10-7-11(16)9-12(17)8-10/h1,7-9,13,21H,3-6H2,(H,18,22)/t13-/m1/s1
InChIKey
VDSOJXABCYAJIH-CYBMUJFWSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

147 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 42.22  LDD1816 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 23.43  LDD1816 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 38.32  LDD1816 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 30.06  LDD1816 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 48.17  LDD1816 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 20.53  LDD1816 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 99.73  LDD1816 
Acid ceramidase (ASAH1) LDTP05905 32.22  LDD1816 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 20.11  LDD1816 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 20.25  LDD1816 
Adenosine deaminase (ADA) LDTP01803 21.11  LDD1816 
ADP-dependent glucokinase (ADPGK) LDTP11127 50.21  LDD1816 
ADP-ribosylation factor-like protein 1 (ARL1) LDTP03900 25.81  LDD1816 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 41.07  LDD1816 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 56.49  LDD1816 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 27.10  LDD1816 
Antigen peptide transporter 1 (TAP1) LDTP05408 23.92  LDD1816 
Atlastin-2 (ATL2) LDTP09251 27.28  LDD1816 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 22.16  LDD1816 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 25.63  LDD1816 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 25.46  LDD1816 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 20.97  LDD1816 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 27.67  LDD1816 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 44.63  LDD1816 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 24.93  LDD1816 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 58.49  LDD1816 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 37.53  LDD1816 
Cartilage-associated protein (CRTAP) LDTP01300 31.56  LDD1816 
Catechol O-methyltransferase (COMT) LDTP03145 37.79  LDD1816 
Ceramide synthase 2 (CERS2) LDTP10329 40.22  LDD1816 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 29.24  LDD1816 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 35.02  LDD1816 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 99.73  LDD1816 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 28.44  LDD1816 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1816 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 84.45  LDD1816 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1816 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 33.36  LDD1816 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 51.27  LDD1816 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 34.54  LDD1816 
Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) LDTP08177 22.63  LDD1816 
Delta(24)-sterol reductase (DHCR24) LDTP06375 30.70  LDD1816 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 27.10  LDD1816 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 36.50  LDD1816 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 46.85  LDD1816 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 28.25  LDD1816 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 39.95  LDD1816 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 67.65  LDD1816 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 22.63  LDD1816 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 20.68  LDD1816 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 22.63  LDD1816 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 35.75  LDD1816 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 20.11  LDD1816 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 30.06  LDD1816 
Ferrochelatase, mitochondrial (FECH) LDTP03198 20.68  LDD1816 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 21.71  LDD1816 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 20.53  LDD1816 
Glutathione S-transferase Mu 3 (GSTM3) LDTP03103 21.86  LDD1816 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 24.76  LDD1816 
Glycerophosphodiester phosphodiesterase 1 (GDE1) LDTP12886 31.34  LDD1816 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 25.81  LDD1816 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 22.78  LDD1816 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 25.81  LDD1816 
GTP-binding protein SAR1a (SAR1A) LDTP12470 22.78  LDD1816 
Heme oxygenase 1 (HMOX1) LDTP02359 83.87  LDD1816 
Heme oxygenase 2 (HMOX2) LDTP03540 70.03  LDD1816 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 30.27  LDD1816 
Hexokinase-2 (HK2) LDTP04531 22.63  LDD1816 
Holocytochrome c-type synthase (HCCS) LDTP04581 25.28  LDD1816 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 55.33  LDD1816 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 27.47  LDD1816 
Ketosamine-3-kinase (FN3KRP) LDTP16025 45.25  LDD1816 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 20.53  LDD1816 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 35.75  LDD1816 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 46.85  LDD1816 
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (DBT) LDTP02550 20.68  LDD1816 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 22.16  LDD1816 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 58.49  LDD1816 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 31.78  LDD1816 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 37.53  LDD1816 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 23.92  LDD1816 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 40.22  LDD1816 
Lysosomal acid phosphatase (ACP2) LDTP02539 27.67  LDD1816 
Lysosomal alpha-glucosidase (GAA) LDTP02486 35.75  LDD1816 
Lysosomal protective protein (CTSA) LDTP02505 23.10  LDD1816 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 22.78  LDD1816 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 34.06  LDD1816 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 20.82  LDD1816 
Minor histocompatibility antigen H13 (HM13) LDTP09396 37.27  LDD1816 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 31.78  LDD1816 
Mitofusin-1 (MFN1) LDTP08530 26.91  LDD1816 
Multidrug resistance-associated protein 1 (ABCC1) LDTP03671 51.27  LDD1816 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 24.42  LDD1816 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 42.81  LDD1816 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 81.01  LDD1816 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 40.79  LDD1816 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 22.63  LDD1816 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 75.06  LDD1816 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 20.11  LDD1816 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 45.25  LDD1816 
NADPH--cytochrome P450 reductase (POR) LDTP02848 25.63  LDD1816 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 27.86  LDD1816 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 57.28  LDD1816 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 33.36  LDD1816 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 34.54  LDD1816 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 21.11  LDD1816 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 20.97  LDD1816 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 26.17  LDD1816 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 33.13  LDD1816 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 22.16  LDD1816 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 43.41  LDD1816 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 23.92  LDD1816 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 20.82  LDD1816 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 27.28  LDD1816 
Protein disulfide-isomerase (P4HB) LDTP02188 21.56  LDD1816 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 25.46  LDD1816 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 20.11  LDD1816 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 42.22  LDD1816 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 42.22  LDD1816 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 27.28  LDD1816 
Ras-related protein Rab-24 (RAB24) LDTP10020 29.86  LDD1816 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 21.86  LDD1816 
Retinol dehydrogenase 13 (RDH13) LDTP09061 33.36  LDD1816 
Retinol dehydrogenase 14 (RDH14) LDTP12180 20.82  LDD1816 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 35.51  LDD1816 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 20.53  LDD1816 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 22.78  LDD1816 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 54.95  LDD1816 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 28.64  LDD1816 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 20.82  LDD1816 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 22.47  LDD1816 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 21.71  LDD1816 
Sphingosine kinase 2 (SPHK2) LDTP12490 28.84  LDD1816 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 35.51  LDD1816 
Squalene monooxygenase (SQLE) LDTP06142 26.17  LDD1816 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 22.63  LDD1816 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 29.86  LDD1816 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 29.24  LDD1816 
Trimethylguanosine synthase (TGS1) LDTP10780 27.67  LDD1816 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 44.63  LDD1816 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 28.84  LDD1816 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 31.34  LDD1816 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 22.32  LDD1816 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 22.78  LDD1816 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 21.26  LDD1816 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 40.79  LDD1816 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 27.28  LDD1816 
------------------------------------------------------------------------------------
⏷ Show the Full List of 147 Enzyme
125 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 33.59  LDD1816 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 70.03  LDD1816 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 26.35  LDD1816 
Anion exchange protein 2 (SLC4A2) LDTP02061 23.92  LDD1816 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 35.26  LDD1816 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 25.99  LDD1816 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 53.45  LDD1816 
BRI3-binding protein (BRI3BP) LDTP15648 99.73  LDD1816 
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB) LDTP12725 20.97  LDD1816 
Calnexin (CANX) LDTP03405 21.86  LDD1816 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 24.76  LDD1816 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 20.82  LDD1816 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 41.07  LDD1816 
Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) LDTP03064 32.00  LDD1816 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 47.50  LDD1816 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 33.82  LDD1816 
Derlin-1 (DERL1) LDTP11245 37.27  LDD1816 
Derlin-2 (DERL2) LDTP11634 24.93  LDD1816 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 22.47  LDD1816 
Endophilin-B1 (SH3GLB1) LDTP13953 20.39  LDD1816 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 26.54  LDD1816 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 51.63  LDD1816 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.73  LDD1816 
Erlin-1 (ERLIN1) LDTP01234 29.65  LDD1816 
Erlin-2 (ERLIN2) LDTP01455 38.05  LDD1816 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 34.30  LDD1816 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 21.41  LDD1816 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 22.16  LDD1816 
Guided entry of tail-anchored proteins factor CAMLG (CAMLG) LDTP04227 30.27  LDD1816 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 25.11  LDD1816 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 29.24  LDD1816 
Importin-9 (IPO9) LDTP10663 37.01  LDD1816 
Integral membrane protein 2C (ITM2C) LDTP12451 20.82  LDD1816 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 25.63  LDD1816 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 24.59  LDD1816 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 34.78  LDD1816 
Lysosome membrane protein 2 (SCARB2) LDTP06034 36.50  LDD1816 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 21.56  LDD1816 
Magnesium transporter protein 1 (MAGT1) LDTP11732 20.97  LDD1816 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 39.95  LDD1816 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 52.71  LDD1816 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 39.40  LDD1816 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 39.40  LDD1816 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 20.53  LDD1816 
Metal transporter CNNM3 (CNNM3) LDTP09144 23.43  LDD1816 
Metal transporter CNNM4 (CNNM4) LDTP07537 21.11  LDD1816 
Metaxin-1 (MTX1) LDTP05900 87.43  LDD1816 
Metaxin-2 (MTX2) LDTP01217 22.78  LDD1816 
MICOS complex subunit MIC26 (APOO) LDTP11250 40.79  LDD1816 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 29.24  LDD1816 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 26.72  LDD1816 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 32.67  LDD1816 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 35.75  LDD1816 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 56.10  LDD1816 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 57.68  LDD1816 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1816 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1816 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 38.32  LDD1816 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 22.78  LDD1816 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 45.25  LDD1816 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 25.81  LDD1816 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 38.32  LDD1816 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 23.59  LDD1816 
Mpv17-like protein 2 (MPV17L2) LDTP14952 53.08  LDD1816 
Nucleoporin NDC1 (NDC1) LDTP11213 22.94  LDD1816 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 43.71  LDD1816 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 26.72  LDD1816 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 29.65  LDD1816 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 30.48  LDD1816 
PRA1 family protein 2 (PRAF2) LDTP01060 35.75  LDD1816 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 32.00  LDD1816 
Prosaposin (PSAP) LDTP02215 45.57  LDD1816 
Protein ERGIC-53 (LMAN1) LDTP04237 38.05  LDD1816 
Protein GPR107 (GPR107) LDTP07236 35.26  LDD1816 
Protein GPR108 (GPR108) LDTP12383 71.01  LDD1816 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 51.63  LDD1816 
Protein tweety homolog 3 (TTYH3) LDTP11615 39.95  LDD1816 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 47.18  LDD1816 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 33.36  LDD1816 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 23.26  LDD1816 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 40.22  LDD1816 
Receptor expression-enhancing protein 6 (REEP6) LDTP10398 21.71  LDD1816 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 23.92  LDD1816 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 20.82  LDD1816 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 22.32  LDD1816 
Sideroflexin-4 (SFXN4) LDTP07531 23.59  LDD1816 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 22.16  LDD1816 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 24.59  LDD1816 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 95.01  LDD1816 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 30.48  LDD1816 
Sorting nexin-19 (SNX19) LDTP09788 28.64  LDD1816 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 25.99  LDD1816 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 28.05  LDD1816 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 79.89  LDD1816 
Stomatin (STOM) LDTP03380 28.84  LDD1816 
Surfeit locus protein 4 (SURF4) LDTP00592 22.94  LDD1816 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 37.27  LDD1816 
Syntenin-1 (SDCBP) LDTP00310 22.32  LDD1816 
Tetraspanin-3 (TSPAN3) LDTP16813 50.21  LDD1816 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 24.42  LDD1816 
THO complex subunit 1 (THOC1) LDTP10317 22.47  LDD1816 
THO complex subunit 6 homolog (THOC6) LDTP08315 20.97  LDD1816 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 35.02  LDD1816 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1816 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 26.17  LDD1816 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 21.41  LDD1816 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 23.75  LDD1816 
Transmembrane protein 126A (TMEM126A) LDTP15948 36.50  LDD1816 
Transmembrane protein 14C (TMEM14C) LDTP12979 21.26  LDD1816 
Transmembrane protein 199 (TMEM199) LDTP08881 62.68  LDD1816 
Transmembrane protein 201 (TMEM201) LDTP07058 23.92  LDD1816 
Transmembrane protein 205 (TMEM205) LDTP07667 21.26  LDD1816 
Transmembrane protein 214 (TMEM214) LDTP07477 22.78  LDD1816 
Transmembrane protein 230 (TMEM230) LDTP10065 39.12  LDD1816 
Transmembrane protein 245 (TMEM245) LDTP15979 30.70  LDD1816 
Transmembrane protein 33 (TMEM33) LDTP04787 26.72  LDD1816 
Transmembrane protein 59 (TMEM59) LDTP11406 20.25  LDD1816 
Transmembrane protein 87A (TMEM87A) LDTP15481 27.67  LDD1816 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 31.12  LDD1816 
Vang-like protein 1 (VANGL1) LDTP09288 22.47  LDD1816 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 70.03  LDD1816 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 75.58  LDD1816 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 48.17  LDD1816 
Volume-regulated anion channel subunit LRRC8C (LRRC8C) LDTP09459 22.78  LDD1816 
Wolframin (WFS1) LDTP01380 22.01  LDD1816 
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⏷ Show the Full List of 125 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 42.22  LDD1816 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 26.54  LDD1816 
Leukocyte surface antigen CD47 (CD47) LDTP05572 30.27  LDD1816 
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102 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 23.10  LDD1816 
Anaphase-promoting complex subunit 2 (ANAPC2) LDTP13412 25.81  LDD1816 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 21.41  LDD1816 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1816 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 35.51  LDD1816 
BLOC-2 complex member HPS6 (HPS6) LDTP08420 21.86  LDD1816 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 24.42  LDD1816 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 21.11  LDD1816 
Centromere protein K (CENPK) LDTP11143 43.11  LDD1816 
Charged multivesicular body protein 7 (CHMP7) LDTP09589 22.78  LDD1816 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 24.08  LDD1816 
Cytochrome c oxidase assembly factor 1 homolog (COA1) LDTP15944 54.19  LDD1816 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 86.22  LDD1816 
DCC-interacting protein 13-alpha (APPL1) LDTP13451 42.52  LDD1816 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 22.01  LDD1816 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 26.35  LDD1816 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 22.01  LDD1816 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 29.04  LDD1816 
Emerin (EMD) LDTP04356 27.67  LDD1816 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 33.59  LDD1816 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 40.22  LDD1816 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1816 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 22.94  LDD1816 
Ganglioside GM2 activator (GM2A) LDTP02927 24.42  LDD1816 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 25.28  LDD1816 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 27.47  LDD1816 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 44.32  LDD1816 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 33.13  LDD1816 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 21.26  LDD1816 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 21.71  LDD1816 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 27.86  LDD1816 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 31.34  LDD1816 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 53.08  LDD1816 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 27.10  LDD1816 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 58.49  LDD1816 
Leukocyte receptor cluster member 8 (LENG8) LDTP10703 20.25  LDD1816 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 29.86  LDD1816 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 37.01  LDD1816 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 22.47  LDD1816 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 36.00  LDD1816 
MICOS complex subunit MIC27 (APOOL) LDTP07718 23.75  LDD1816 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 55.72  LDD1816 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 29.86  LDD1816 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1816 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1816 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 25.81  LDD1816 
Negative elongation factor B (NELFB) LDTP09679 20.68  LDD1816 
Nicastrin (NCSTN) LDTP09787 26.91  LDD1816 
Nucleobindin-1 (NUCB1) LDTP05375 64.45  LDD1816 
Nucleobindin-2 (NUCB2) LDTP05160 70.52  LDD1816 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 28.44  LDD1816 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 22.94  LDD1816 
Nurim (NRM) LDTP08606 33.13  LDD1816 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 37.27  LDD1816 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 99.73  LDD1816 
Pre-mRNA-splicing factor SPF27 (BCAS2) LDTP01358 28.05  LDD1816 
PRELI domain containing protein 3B (PRELID3B) LDTP18569 75.58  LDD1816 
PRELI domain-containing protein 1, mitochondrial (PRELID1) LDTP13807 35.02  LDD1816 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 29.86  LDD1816 
Protein CEBPZOS (CEBPZOS) LDTP18883 99.73  LDD1816 
Protein FAM114A2 (FAM114A2) LDTP16080 53.45  LDD1816 
Protein FAM162A (FAM162A) LDTP10056 67.18  LDD1816 
Protein FAM177A1 (FAM177A1) LDTP15398 38.05  LDD1816 
Protein FAM3C (FAM3C) LDTP09773 53.08  LDD1816 
Protein jagunal homolog 1 (JAGN1) LDTP08904 33.59  LDD1816 
Protein LYRIC (MTDH) LDTP08224 39.67  LDD1816 
Protein MTSS 2 (MTSS2) LDTP07916 24.08  LDD1816 
Protein SET (SET) LDTP05277 21.71  LDD1816 
Protein UXT (UXT) LDTP13125 22.16  LDD1816 
Protein YIF1A (YIF1A) LDTP01494 35.02  LDD1816 
Protein YIF1B (YIF1B) LDTP06948 34.54  LDD1816 
Protein YIPF4 (YIPF4) LDTP11167 27.28  LDD1816 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 41.64  LDD1816 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 20.39  LDD1816 
Reticulocalbin-2 (RCN2) LDTP06097 28.84  LDD1816 
Reticulon-2 (RTN2) LDTP01167 43.41  LDD1816 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1816 
Reticulon-4 (RTN4) LDTP12412 72.00  LDD1816 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 42.22  LDD1816 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 25.81  LDD1816 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 30.48  LDD1816 
Synaptogyrin-2 (SYNGR2) LDTP00859 40.50  LDD1816 
Syntaxin-10 (STX10) LDTP00986 32.67  LDD1816 
Syntaxin-18 (STX18) LDTP13086 62.25  LDD1816 
Syntaxin-8 (STX8) LDTP13664 24.25  LDD1816 
Tetraspanin-6 (TSPAN6) LDTP14458 43.41  LDD1816 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 43.71  LDD1816 
TraB domain-containing protein (TRABD) LDTP19963 39.95  LDD1816 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 27.67  LDD1816 
Transducin beta-like protein 2 (TBL2) LDTP16285 27.10  LDD1816 
Translocon-associated protein subunit delta (SSR4) LDTP04425 22.32  LDD1816 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 24.42  LDD1816 
Transmembrane protein 209 (TMEM209) LDTP18272 25.11  LDD1816 
Tropomodulin-1 (TMOD1) LDTP03425 21.86  LDD1816 
Tumor protein D52 (TPD52) LDTP04703 24.59  LDD1816 
U6 snRNA-associated Sm-like protein LSm5 (LSM5) LDTP14080 22.16  LDD1816 
U6 snRNA-associated Sm-like protein LSm6 (LSM6) LDTP04980 20.68  LDD1816 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 45.57  LDD1816 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 22.16  LDD1816 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 29.86  LDD1816 
Vesicle-trafficking protein SEC22b (SEC22B) LDTP01206 20.11  LDD1816 
Vimentin (VIM) LDTP02297 22.01  LDD1816 
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⏷ Show the Full List of 102 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1816 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587