Details of the Probe

General Information of Probe

Probe ID
LDPC0570
Probe Name
C349
Synonyms
Z4282859610
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 363.5
Lipid-water partition coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C21H25N5O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[(1-phenyl-3-propan-2-ylpyrazol-4-yl)methyl]propanamide
Canonical SMILES
CC(C)C1=NN(C=C1CNC(=O)CCC2(N=N2)CCC#C)C3=CC=CC=C3
InChI
InChI=1S/C21H25N5O/c1-4-5-12-21(24-25-21)13-11-19(27)22-14-17-15-26(23-20(17)16(2)3)18-9-7-6-8-10-18/h1,6-10,15-16H,5,11-14H2,2-3H3,(H,22,27)
InChIKey
IWHHQMKRGWBQIN-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

172 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 21.11  LDD2010 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) LDTP02984 10.20  LDD2010 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 22.32  LDD2010 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 11.88  LDD2010 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 9.92  LDD2010 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 8.51  LDD2010 
Acid ceramidase (ASAH1) LDTP05905 26.17  LDD2010 
Acyl-CoA 6-desaturase (FADS2) LDTP01699 9.13  LDD2010 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 14.42  LDD2010 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 9.65  LDD2010 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 30.27  LDD2010 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 11.79  LDD2010 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.80  LDD2010 
Antigen peptide transporter 2 (TAP2) LDTP05409 11.16  LDD2010 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 9.58  LDD2010 
Atlastin-2 (ATL2) LDTP09251 14.12  LDD2010 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 18.00  LDD2010 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 10.13  LDD2010 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 10.34  LDD2010 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 11.08  LDD2010 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 12.55  LDD2010 
Beta-galactosidase (GLB1) LDTP02837 14.12  LDD2010 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 14.52  LDD2010 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 41.64  LDD2010 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 39.95  LDD2010 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 22.94  LDD2010 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 12.64  LDD2010 
Catechol O-methyltransferase (COMT) LDTP03145 17.03  LDD2010 
Ceramide synthase 1 (CERS1) LDTP03394 12.91  LDD2010 
Ceramide synthase 2 (CERS2) LDTP10329 40.79  LDD2010 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 29.45  LDD2010 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 21.11  LDD2010 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 47.18  LDD2010 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 39.40  LDD2010 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD2010 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 35.02  LDD2010 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.78  LDD2010 
DCN1-like protein 4 (DCUN1D4) LDTP09799 38.05  LDD2010 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 8.69  LDD2010 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 9.99  LDD2010 
Dehydrogenase/reductase SDR family member 7B (DHRS7B) LDTP07402 8.94  LDD2010 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 20.53  LDD2010 
Delta(24)-sterol reductase (DHCR24) LDTP06375 19.03  LDD2010 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 18.64  LDD2010 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 10.06  LDD2010 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 8.75  LDD2010 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 21.11  LDD2010 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 10.13  LDD2010 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 13.36  LDD2010 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 10.63  LDD2010 
E3 ubiquitin-protein ligase synoviolin (SYVN1) LDTP08203 12.21  LDD2010 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 25.11  LDD2010 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 10.41  LDD2010 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 26.35  LDD2010 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 17.15  LDD2010 
Ephrin type-A receptor 7 (EPHA7) LDTP06370 13.55  LDD2010 
Epoxide hydrolase 1 (EPHX1) LDTP02175 13.55  LDD2010 
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) LDTP09063 8.63  LDD2010 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 41.64  LDD2010 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 9.45  LDD2010 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 8.57  LDD2010 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 11.08  LDD2010 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 8.51  LDD2010 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 18.00  LDD2010 
GPI-anchor transamidase (PIGK) LDTP09835 11.00  LDD2010 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 9.92  LDD2010 
Haloacid dehalogenase-like hydrolase domain-containing protein 3 (HDHD3) LDTP15879 16.91  LDD2010 
Heme A synthase COX15 (COX15) LDTP07931 15.89  LDD2010 
Heme oxygenase 1 (HMOX1) LDTP02359 49.52  LDD2010 
Heme oxygenase 2 (HMOX2) LDTP03540 75.58  LDD2010 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 11.79  LDD2010 
Hexokinase-2 (HK2) LDTP04531 11.24  LDD2010 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 33.59  LDD2010 
Holocytochrome c-type synthase (HCCS) LDTP04581 11.00  LDD2010 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 48.17  LDD2010 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.03  LDD2010 
Lathosterol oxidase (SC5D) LDTP01329 18.77  LDD2010 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 27.28  LDD2010 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 20.53  LDD2010 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 17.15  LDD2010 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 20.82  LDD2010 
Lysocardiolipin acyltransferase 1 (LCLAT1) LDTP07679 9.92  LDD2010 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 44.32  LDD2010 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 21.26  LDD2010 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 12.04  LDD2010 
Lysophospholipase D GDPD1 (GDPD1) LDTP09000 8.51  LDD2010 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 14.03  LDD2010 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 24.08  LDD2010 
Lysosomal alpha-glucosidase (GAA) LDTP02486 10.27  LDD2010 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 18.00  LDD2010 
Lysosomal protective protein (CTSA) LDTP02505 23.59  LDD2010 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 10.41  LDD2010 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 10.63  LDD2010 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 47.18  LDD2010 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 10.63  LDD2010 
Minor histocompatibility antigen H13 (HM13) LDTP09396 14.83  LDD2010 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 11.08  LDD2010 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 12.64  LDD2010 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 9.58  LDD2010 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 17.03  LDD2010 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 16.45  LDD2010 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 28.84  LDD2010 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 26.17  LDD2010 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 19.56  LDD2010 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 76.11  LDD2010 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 44.94  LDD2010 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 9.99  LDD2010 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 23.75  LDD2010 
NADPH--cytochrome P450 reductase (POR) LDTP02848 14.12  LDD2010 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 31.34  LDD2010 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 28.25  LDD2010 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 14.42  LDD2010 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 15.67  LDD2010 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 11.79  LDD2010 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 17.75  LDD2010 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 16.68  LDD2010 
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) LDTP09155 9.85  LDD2010 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 9.71  LDD2010 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 9.92  LDD2010 
Phosphatidylserine lipase ABHD16A (ABHD16A) LDTP01704 14.42  LDD2010 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 11.79  LDD2010 
Phospholipase A2 group XV (PLA2G15) LDTP09088 20.39  LDD2010 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 11.39  LDD2010 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 13.74  LDD2010 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 31.34  LDD2010 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 41.93  LDD2010 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 17.88  LDD2010 
Presequence protease, mitochondrial (PITRM1) LDTP07003 9.13  LDD2010 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 9.78  LDD2010 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 12.21  LDD2010 
Prolyl endopeptidase-like (PREPL) LDTP06849 17.03  LDD2010 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 9.71  LDD2010 
Prostaglandin reductase 3 (PTGR3) LDTP15422 62.68  LDD2010 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 13.55  LDD2010 
Protein arginine methyltransferase NDUFAF7, mitochondrial (NDUFAF7) LDTP07961 8.69  LDD2010 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 15.14  LDD2010 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 11.96  LDD2010 
Protein O-GlcNAcase (OGA) LDTP00988 11.24  LDD2010 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 11.00  LDD2010 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 54.19  LDD2010 
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) LDTP04925 9.51  LDD2010 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 18.00  LDD2010 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 9.32  LDD2010 
Ras-related protein Rab-10 (RAB10) LDTP04895 11.47  LDD2010 
Ras-related protein Rab-24 (RAB24) LDTP10020 11.71  LDD2010 
Ras-related protein Rab-2A (RAB2A) LDTP04892 8.51  LDD2010 
Receptor-type tyrosine-protein phosphatase F (PTPRF) LDTP02499 10.13  LDD2010 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 41.93  LDD2010 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 27.67  LDD2010 
Retinol dehydrogenase 13 (RDH13) LDTP09061 13.09  LDD2010 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 36.25  LDD2010 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 20.25  LDD2010 
Serine/threonine-protein kinase VRK2 (VRK2) LDTP08378 15.35  LDD2010 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 11.24  LDD2010 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 10.13  LDD2010 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 11.08  LDD2010 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 10.78  LDD2010 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 33.82  LDD2010 
Squalene monooxygenase (SQLE) LDTP06142 29.45  LDD2010 
Stearoyl-CoA desaturase (SCD) LDTP00344 9.99  LDD2010 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 13.18  LDD2010 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 14.72  LDD2010 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 11.24  LDD2010 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 20.82  LDD2010 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 9.51  LDD2010 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 12.55  LDD2010 
UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) LDTP12851 13.45  LDD2010 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 11.00  LDD2010 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 13.55  LDD2010 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 9.19  LDD2010 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 8.57  LDD2010 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 51.63  LDD2010 
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⏷ Show the Full List of 172 Enzyme
137 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 9.51  LDD2010 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 28.25  LDD2010 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 10.70  LDD2010 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 17.51  LDD2010 
Anoctamin-10 (ANO10) LDTP12704 16.80  LDD2010 
AP-3 complex subunit delta-1 (AP3D1) LDTP00383 8.94  LDD2010 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 12.73  LDD2010 
ATP synthase subunit a (MT-ATP6) LDTP01804 71.01  LDD2010 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 10.41  LDD2010 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 25.46  LDD2010 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 8.82  LDD2010 
Calcium load-activated calcium channel (TMCO1) LDTP13599 8.57  LDD2010 
Calnexin (CANX) LDTP03405 8.94  LDD2010 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 11.96  LDD2010 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 18.90  LDD2010 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 17.39  LDD2010 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 79.89  LDD2010 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 20.11  LDD2010 
Derlin-1 (DERL1) LDTP11245 65.34  LDD2010 
Derlin-2 (DERL2) LDTP11634 8.51  LDD2010 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 12.21  LDD2010 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 73.01  LDD2010 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 22.32  LDD2010 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 9.71  LDD2010 
Exocyst complex component 1 (EXOC1) LDTP12661 9.19  LDD2010 
Gasdermin-E (GSDME) LDTP00970 11.79  LDD2010 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 10.20  LDD2010 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 15.35  LDD2010 
Guided entry of tail-anchored proteins factor CAMLG (CAMLG) LDTP04227 14.12  LDD2010 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 9.00  LDD2010 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 12.55  LDD2010 
Integral membrane protein 2C (ITM2C) LDTP12451 12.21  LDD2010 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 9.06  LDD2010 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 9.25  LDD2010 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 13.64  LDD2010 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 20.97  LDD2010 
Lysosome membrane protein 2 (SCARB2) LDTP06034 38.05  LDD2010 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 10.56  LDD2010 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 33.36  LDD2010 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 45.89  LDD2010 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 9.06  LDD2010 
Metal transporter CNNM4 (CNNM4) LDTP07537 11.71  LDD2010 
Metaxin-1 (MTX1) LDTP05900 20.25  LDD2010 
Metaxin-2 (MTX2) LDTP01217 13.18  LDD2010 
Metaxin-3 (MTX3) LDTP14970 13.45  LDD2010 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 13.83  LDD2010 
MICOS complex subunit MIC26 (APOO) LDTP11250 27.47  LDD2010 
MICOS complex subunit MIC60 (IMMT) LDTP06660 9.38  LDD2010 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 11.55  LDD2010 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 10.34  LDD2010 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 14.62  LDD2010 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 14.22  LDD2010 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 37.53  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 10.85  LDD2010 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 34.30  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 75.58  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 39.67  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 50.91  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 21.11  LDD2010 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 11.00  LDD2010 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 35.26  LDD2010 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 18.90  LDD2010 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 18.77  LDD2010 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 33.59  LDD2010 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 13.18  LDD2010 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 17.88  LDD2010 
Nucleoporin NDC1 (NDC1) LDTP11213 22.78  LDD2010 
Nucleoporin NUP188 (NUP188) LDTP07064 13.64  LDD2010 
Nucleoporin NUP35 (NUP35) LDTP09204 8.63  LDD2010 
Nucleoporin Nup37 (NUP37) LDTP09203 11.00  LDD2010 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 18.51  LDD2010 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 8.82  LDD2010 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 8.75  LDD2010 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 8.63  LDD2010 
PRA1 family protein 2 (PRAF2) LDTP01060 19.03  LDD2010 
PRA1 family protein 3 (ARL6IP5) LDTP01352 10.20  LDD2010 
Prolactin regulatory element-binding protein (PREB) LDTP12272 9.71  LDD2010 
Protein ERGIC-53 (LMAN1) LDTP04237 9.58  LDD2010 
Protein GPR107 (GPR107) LDTP07236 20.53  LDD2010 
Protein GPR108 (GPR108) LDTP12383 10.27  LDD2010 
Protein RER1 (RER1) LDTP00590 11.00  LDD2010 
Protein RFT1 homolog (RFT1) LDTP10073 15.03  LDD2010 
Protein tweety homolog 3 (TTYH3) LDTP11615 70.52  LDD2010 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 25.99  LDD2010 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 46.21  LDD2010 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 15.89  LDD2010 
Reticulon-1 (RTN1) LDTP06633 72.50  LDD2010 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 23.92  LDD2010 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 11.39  LDD2010 
Secretory carrier-associated membrane protein 4 (SCAMP4) LDTP09987 10.85  LDD2010 
Sideroflexin-1 (SFXN1) LDTP12090 10.13  LDD2010 
Sideroflexin-2 (SFXN2) LDTP10621 9.38  LDD2010 
Sideroflexin-4 (SFXN4) LDTP07531 24.42  LDD2010 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 22.32  LDD2010 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 62.25  LDD2010 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 15.14  LDD2010 
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) LDTP12809 9.06  LDD2010 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 48.84  LDD2010 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 9.38  LDD2010 
Sortilin (SORT1) LDTP10885 8.75  LDD2010 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 10.41  LDD2010 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 22.16  LDD2010 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 16.34  LDD2010 
Stomatin (STOM) LDTP03380 10.41  LDD2010 
SUN domain-containing protein 1 (SUN1) LDTP01454 14.12  LDD2010 
Surfeit locus protein 4 (SURF4) LDTP00592 9.38  LDD2010 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 10.70  LDD2010 
Syntaxin-6 (STX6) LDTP00857 16.34  LDD2010 
Tetraspanin-3 (TSPAN3) LDTP16813 43.11  LDD2010 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 10.41  LDD2010 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 19.56  LDD2010 
Translocation protein SEC62 (SEC62) LDTP15838 9.85  LDD2010 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD2010 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 11.63  LDD2010 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 19.43  LDD2010 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 13.36  LDD2010 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 15.35  LDD2010 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.62  LDD2010 
Transmembrane protein 126A (TMEM126A) LDTP15948 41.36  LDD2010 
Transmembrane protein 199 (TMEM199) LDTP08881 34.54  LDD2010 
Transmembrane protein 201 (TMEM201) LDTP07058 11.79  LDD2010 
Transmembrane protein 205 (TMEM205) LDTP07667 8.51  LDD2010 
Transmembrane protein 214 (TMEM214) LDTP07477 12.47  LDD2010 
Transmembrane protein 230 (TMEM230) LDTP10065 33.13  LDD2010 
Transmembrane protein 245 (TMEM245) LDTP15979 12.38  LDD2010 
Transmembrane protein 33 (TMEM33) LDTP04787 19.70  LDD2010 
Transmembrane protein 65 (TMEM65) LDTP07583 8.51  LDD2010 
Transmembrane protein 87A (TMEM87A) LDTP15481 52.35  LDD2010 
Transport and Golgi organization protein 1 homolog (MIA3) LDTP07002 8.75  LDD2010 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 18.51  LDD2010 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 10.20  LDD2010 
Vacuole membrane protein 1 (VMP1) LDTP10343 13.36  LDD2010 
Vang-like protein 1 (VANGL1) LDTP09288 10.41  LDD2010 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 70.52  LDD2010 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 72.00  LDD2010 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 17.15  LDD2010 
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) LDTP11281 9.71  LDD2010 
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⏷ Show the Full List of 137 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 20.11  LDD2010 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
IgG receptor FcRn large subunit p51 (FCGRT) LDTP04720 21.86  LDD2010 
Leukocyte surface antigen CD47 (CD47) LDTP05572 20.68  LDD2010 
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106 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.14  LDD2010 
AP-3 complex subunit mu-1 (AP3M1) LDTP13908 9.06  LDD2010 
Apolipoprotein L2 (APOL2) LDTP11076 91.77  LDD2010 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 9.45  LDD2010 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 15.24  LDD2010 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 18.77  LDD2010 
Calumenin (CALU) LDTP00887 10.78  LDD2010 
Clustered mitochondria protein homolog (CLUH) LDTP14486 22.01  LDD2010 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 12.38  LDD2010 
Craniofacial development protein 1 (CFDP1) LDTP16193 10.85  LDD2010 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 34.78  LDD2010 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 10.93  LDD2010 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 10.34  LDD2010 
Dynactin subunit 3 (DCTN3) LDTP01359 13.55  LDD2010 
Emerin (EMD) LDTP04356 14.32  LDD2010 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 13.00  LDD2010 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 38.85  LDD2010 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 88.03  LDD2010 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 8.57  LDD2010 
Ganglioside GM2 activator (GM2A) LDTP02927 18.00  LDD2010 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 10.41  LDD2010 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 29.45  LDD2010 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 9.06  LDD2010 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.94  LDD2010 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 11.24  LDD2010 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 8.69  LDD2010 
Intermembrane lipid transfer protein VPS13D (VPS13D) LDTP07192 14.03  LDD2010 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 12.82  LDD2010 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 29.65  LDD2010 
LanC-like protein 2 (LANCL2) LDTP12571 12.30  LDD2010 
Large ribosomal subunit protein mL45 (MRPL45) LDTP15863 9.65  LDD2010 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 11.39  LDD2010 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 13.93  LDD2010 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 12.13  LDD2010 
Lipase maturation factor 2 (LMF2) LDTP15887 13.27  LDD2010 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 17.15  LDD2010 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 11.24  LDD2010 
MICOS complex subunit MIC27 (APOOL) LDTP07718 10.41  LDD2010 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 10.63  LDD2010 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 94.35  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) LDTP14136 11.96  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 10.70  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 10.85  LDD2010 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 14.22  LDD2010 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2010 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 63.56  LDD2010 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 25.11  LDD2010 
Motile sperm domain-containing protein 2 (MOSPD2) LDTP09255 9.45  LDD2010 
NBAS subunit of NRZ tethering complex (NBAS) LDTP00046 10.27  LDD2010 
Negative elongation factor C/D (NELFCD) LDTP08594 11.24  LDD2010 
Neudesin (NENF) LDTP13630 13.18  LDD2010 
Nicastrin (NCSTN) LDTP09787 10.85  LDD2010 
Nucleobindin-1 (NUCB1) LDTP05375 16.91  LDD2010 
Nucleobindin-2 (NUCB2) LDTP05160 64.89  LDD2010 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.82  LDD2010 
Nurim (NRM) LDTP08606 20.97  LDD2010 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 18.77  LDD2010 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 9.25  LDD2010 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 16.91  LDD2010 
Prefoldin subunit 6 (PFDN6) LDTP00573 10.34  LDD2010 
Prohibitin-2 (PHB2) LDTP10924 12.47  LDD2010 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 11.63  LDD2010 
Proline-rich protein PRCC (PRCC) LDTP09850 8.94  LDD2010 
Proteasome adapter and scaffold protein ECM29 (ECPAS) LDTP07255 18.00  LDD2010 
Protein FAM114A2 (FAM114A2) LDTP16080 18.51  LDD2010 
Protein FAM162A (FAM162A) LDTP10056 38.85  LDD2010 
Protein FAM177A1 (FAM177A1) LDTP15398 26.17  LDD2010 
Protein FAM210A (FAM210A) LDTP15793 19.16  LDD2010 
Protein FAM3C (FAM3C) LDTP09773 22.32  LDD2010 
Protein jagunal homolog 1 (JAGN1) LDTP08904 22.78  LDD2010 
Protein LYRIC (MTDH) LDTP08224 51.98  LDD2010 
Protein unc-119 homolog A (UNC119) LDTP05868 15.03  LDD2010 
Protein UXT (UXT) LDTP13125 9.99  LDD2010 
Protein YIF1A (YIF1A) LDTP01494 20.68  LDD2010 
Protein YIPF4 (YIPF4) LDTP11167 12.13  LDD2010 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 9.51  LDD2010 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 11.96  LDD2010 
Required for meiotic nuclear division protein 1 homolog (RMND1) LDTP12729 12.13  LDD2010 
Reticulocalbin-2 (RCN2) LDTP06097 20.11  LDD2010 
Reticulon-2 (RTN2) LDTP01167 37.53  LDD2010 
Reticulon-3 (RTN3) LDTP01522 49.18  LDD2010 
Reticulon-4 (RTN4) LDTP12412 41.36  LDD2010 
RNA-binding protein FUS (FUS) LDTP03775 9.13  LDD2010 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 34.78  LDD2010 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 10.78  LDD2010 
Superkiller complex protein 3 (SKIC3) LDTP07574 20.11  LDD2010 
Synaptogyrin-2 (SYNGR2) LDTP00859 17.03  LDD2010 
Syntaxin-10 (STX10) LDTP00986 38.05  LDD2010 
Syntaxin-18 (STX18) LDTP13086 42.81  LDD2010 
Syntaxin-7 (STX7) LDTP00632 13.36  LDD2010 
Tetraspanin-6 (TSPAN6) LDTP14458 81.57  LDD2010 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 10.20  LDD2010 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 11.71  LDD2010 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 58.89  LDD2010 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 13.45  LDD2010 
TraB domain-containing protein (TRABD) LDTP19963 24.42  LDD2010 
Transducin beta-like protein 2 (TBL2) LDTP16285 12.13  LDD2010 
Translocon-associated protein subunit delta (SSR4) LDTP04425 8.94  LDD2010 
Transmembrane protein 209 (TMEM209) LDTP18272 30.27  LDD2010 
Trophoblast glycoprotein (TPBG) LDTP05960 9.00  LDD2010 
Tubulin beta chain (TUBB) LDTP02205 11.63  LDD2010 
Tubulin beta-2B chain (TUBB2B) LDTP11277 9.85  LDD2010 
Tubulin beta-4A chain (TUBB4A) LDTP02037 9.71  LDD2010 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 61.82  LDD2010 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 9.06  LDD2010 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 11.31  LDD2010 
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⏷ Show the Full List of 106 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2010 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587