Details of the Target

General Information of Target

Target ID LDTP15793
Target Name Protein FAM210A (FAM210A)
Gene Name FAM210A
Gene ID 125228
Synonyms
C18orf19; Protein FAM210A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNVMLENYKNLVFLAGIAVSKQDPITSLEQEKEPWNMKICEMVDESPAMCSSFTRDLWPE
QDIKDSFQQVILRRHGKCEHENLQLRKGSANVVECKVYKKGYELNQCLTTTQSKIFPCDK
YIKVFHKIFNSNRHKTRHTGEKPFKCKKCDESFCMLLHLHQHKRIHIRENSYQCEECDKV
FKRFSTLTRHKRVHTGEKPFKCEECGKAFKHSSTLTTHKMIHTGEKPYRCEECGKAFYHS
SHLTTHKVIHTGEKPFKCEECGKAFNHPSALTTHKFIHVKEKPYKCEECDKAFNRFSYLT
KHKIIHSGEKSYKCEQCGKGFNWSSTLTKHKRIHTGEKPYKCEECGKAFNVSSHLTTHKM
IHTGEKPYKCEECGKAFNHSSKLTIHKIIHTGEKPYKCEECGKAFNQSSNLTKHKIIHTG
EKLYKCEECGKAFNRSSNLTTHKRIHTGEKPYKCEECGKAFNRSSNLTKHNIIHTGEKSY
KCEECGKAFNQSSTLTKHRKIQQGMVAHACNPNTLRGLGEQIARSGVQDQPGQHGKTPSL
LKIQKFAGCGGRRL
Target Bioclass
Other
Family
FAM210 family
Subcellular location
Membrane
Function May play a role in the structure and strength of both muscle and bone.
Uniprot ID
Q96ND0
Ensemble ID
ENST00000322247.7
HGNC ID
HGNC:28346

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TH211
 Probe Info  		Y231(20.00)  LDD0260  [1]
STPyne
 Probe Info  		K257(10.00)  LDD0277  [2]
PAL-AfBPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C218
 Probe Info  		10.70  LDD1892  [3]
C220
 Probe Info  		11.88  LDD1894  [3]
C246
 Probe Info  		13.18  LDD1919  [3]
C349
 Probe Info  		19.16  LDD2010  [3]
C350
 Probe Info  		42.52  LDD2011  [3]
C388
 Probe Info  		99.73  LDD2047  [3]
C390
 Probe Info  		38.32  LDD2049  [3]

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587