Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C388  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 169 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01803  Adenosine deaminase (ADA) 99.7
 LDTP11127  ADP-dependent glucokinase (ADPGK) 99.7
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 99.7
 LDTP03145  Catechol O-methyltransferase (COMT) 99.7
 LDTP10329  Ceramide synthase 2 (CERS2) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 99.7
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 99.7
 LDTP01769  Dihydrofolate reductase (DHFR) 99.7
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 99.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 99.7
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 99.7
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 99.7
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 99.7
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 99.7
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 99.7
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 95.0
 LDTP00400  Torsin-1B (TOR1B) 95.0
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 94.4
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 90.5
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 88.6
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 84.4
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 83.9
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 82.7
 LDTP10020  Ras-related protein Rab-24 (RAB24) 82.1
 LDTP01513  NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) 81.0
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 80.4
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 80.4
 LDTP12790  Glutaminyl-peptide cyclotransferase-like protein (QPCTL) 79.3
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 79.3
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 78.2
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 77.7
 LDTP10201  Atypical kinase COQ8B, mitochondrial (COQ8B) 76.6
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 76.6
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 74.5
 LDTP14435  Cytochrome b-c1 complex subunit 10 (UQCR11) 74.5
 LDTP17305  Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) 74.5
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 73.0
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 71.5
 LDTP03394  Ceramide synthase 1 (CERS1) 71.0
 LDTP12708  Distal membrane-arm assembly complex protein 2 (DMAC2) 71.0
 LDTP16258  N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL) 71.0
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 68.1
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 66.7
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 66.7
 LDTP11247  Oxidoreductase HTATIP2 (HTATIP2) 66.3
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 65.8
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 65.3
 LDTP15132  2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3) 64.9
 LDTP09000  Lysophospholipase D GDPD1 (GDPD1) 63.6
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 63.1
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 63.1
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 62.7
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 62.7
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 62.2
 LDTP07756  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) 62.2
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 61.8
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 60.5
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 60.1
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 59.7
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 58.9
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 58.5
 LDTP09251  Atlastin-2 (ATL2) 56.9
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 56.5
 LDTP06142  Squalene monooxygenase (SQLE) 56.1
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 55.7
 LDTP13367  Glutathione hydrolase 7 (GGT7) 54.9
 LDTP07057  Protein phosphatase 1L (PPM1L) 54.9
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 54.6
 LDTP15155  Thiol S-methyltransferase TMT1B (TMT1B) 54.2
 LDTP14214  Dolichyl-phosphate beta-glucosyltransferase (ALG5) 53.1
 LDTP09031  Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) 53.1
 LDTP06325  3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) 52.7
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 52.7
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 52.7
 LDTP11318  ADP-ribose pyrophosphatase, mitochondrial (NUDT9) 52.3
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 52.3
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B) 51.3
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 51.3
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 50.9
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 50.9
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 50.2
 LDTP05446  Ubiquitin-protein ligase E3A (UBE3A) 50.2
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 49.9
 LDTP17785  Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPR) 49.5
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 49.2
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 48.8
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 48.5
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 48.5
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 48.2
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 48.2
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 47.8
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 47.8
 LDTP00836  ATPase GET3 (GET3) 47.2
 LDTP01562  Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) 47.2
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 47.2
 LDTP09053  Xyloside xylosyltransferase 1 (XXYLT1) 46.5
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 46.2
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 45.9
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 45.9
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 45.9
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 45.6
 LDTP09620  Soluble calcium-activated nucleotidase 1 (CANT1) 45.6
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 45.3
 LDTP08232  Glycerol-3-phosphate acyltransferase 4 (GPAT4) 45.3
 LDTP07931  Heme A synthase COX15 (COX15) 45.3
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 44.6
 LDTP05905  Acid ceramidase (ASAH1) 44.6
 LDTP11535  Ras-related protein Rab-34 (RAB34) 44.3
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 44.0
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 44.0
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 44.0
 LDTP08378  Serine/threonine-protein kinase VRK2 (VRK2) 44.0
 LDTP05409  Antigen peptide transporter 2 (TAP2) 43.7
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 43.4
 LDTP15097  All-trans-retinol 13,14-reductase (RETSAT) 43.4
 LDTP11448  Alpha-(1,6)-fucosyltransferase (FUT8) 43.4
 LDTP01329  Lathosterol oxidase (SC5D) 43.4
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 43.4
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 43.4
 LDTP15154  Dehydrogenase/reductase SDR family member 13 (DHRS13) 43.1
 LDTP08530  Mitofusin-1 (MFN1) 43.1
 LDTP09364  Retinol dehydrogenase 11 (RDH11) 43.1
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 42.8
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 42.8
 LDTP15962  Protein-L-histidine N-pros-methyltransferase (METTL9) 42.8
 LDTP04895  Ras-related protein Rab-10 (RAB10) 42.8
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 42.8
 LDTP09056  Inactive C-alpha-formylglycine-generating enzyme 2 (SUMF2) 42.5
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 42.2
 LDTP10530  Beta-1,3-galactosyltransferase 6 (B3GALT6) 41.6
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 41.6
 LDTP11437  Peroxisomal trans-2-enoyl-CoA reductase (PECR) 41.4
 LDTP01640  CCR4-NOT transcription complex subunit 4 (CNOT4) 40.5
 LDTP07813  Sulfhydryl oxidase 2 (QSOX2) 40.2
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 39.9
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 39.7
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 39.4
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 39.4
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 39.1
 LDTP07323  Acyl-coenzyme A thioesterase MBLAC2 (MBLAC2) 39.1
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 39.1
 LDTP01514  NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) 39.1
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 38.9
 LDTP12415  Adenosine 5'-monophosphoramidase HINT3 (HINT3) 38.3
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 38.3
 LDTP03842  Squalene synthase (FDFT1) 38.3
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 37.8
 LDTP14189  UbiA prenyltransferase domain-containing protein 1 (UBIAD1) 37.8
 LDTP06721  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) 37.5
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 37.5
 LDTP00462  Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) 37.3
 LDTP06810  Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) 37.3
 LDTP01502  NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) 37.3
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 36.8
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 36.8
 LDTP01004  Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) 36.8
 LDTP01770  NADH-cytochrome b5 reductase 3 (CYB5R3) 36.8
 LDTP10322  Abasic site processing protein HMCES (HMCES) 36.5
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 36.5
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 36.5
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 36.5
 LDTP12610  Obg-like ATPase 1 (OLA1) 36.3
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 36.0
 LDTP04581  Holocytochrome c-type synthase (HCCS) 36.0
 LDTP12386  Polyamine-transporting ATPase 13A2 (ATP13A2) 35.8
Transporter and channel
Click to Show/Hide to Show 144 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01804  ATP synthase subunit a (MT-ATP6) 99.7
 LDTP15648  BRI3-binding protein (BRI3BP) 99.7
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 99.7
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 99.7
 LDTP05900  Metaxin-1 (MTX1) 99.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 99.7
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 99.7
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 99.7
 LDTP16813  Tetraspanin-3 (TSPAN3) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP20002  Transmembrane protein 160 (TMEM160) 99.7
 LDTP10065  Transmembrane protein 230 (TMEM230) 99.7
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 99.7
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 99.7
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 95.7
 LDTP11250  MICOS complex subunit MIC26 (APOO) 93.7
 LDTP10036  BOS complex subunit NCLN (NCLN) 93.1
 LDTP03064  Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) 93.1
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 91.1
 LDTP08881  Transmembrane protein 199 (TMEM199) 90.5
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 88.6
 LDTP15733  Solute carrier family 25 member 44 (SLC25A44) 86.8
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 84.4
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 81.6
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 81.0
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 80.4
 LDTP12636  Lysosomal cobalamin transport escort protein LMBD1 (LMBRD1) 79.3
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 78.8
 LDTP01217  Metaxin-2 (MTX2) 78.2
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 76.6
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 76.1
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 75.1
 LDTP00405  Etoposide-induced protein 2.4 homolog (EI24) 75.1
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 74.5
 LDTP10398  Receptor expression-enhancing protein 6 (REEP6) 74.0
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 73.0
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 71.0
 LDTP06947  Transmembrane protein 128 (TMEM128) 70.5
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 70.0
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 69.6
 LDTP15948  Transmembrane protein 126A (TMEM126A) 65.3
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 64.0
 LDTP07583  Transmembrane protein 65 (TMEM65) 64.0
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 63.1
 LDTP07236  Protein GPR107 (GPR107) 63.1
 LDTP04227  Guided entry of tail-anchored proteins factor CAMLG (CAMLG) 62.7
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 62.7
 LDTP07058  Transmembrane protein 201 (TMEM201) 62.2
 LDTP02215  Prosaposin (PSAP) 61.8
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 61.0
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 59.3
 LDTP10073  Protein RFT1 homolog (RFT1) 57.7
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 57.3
 LDTP15979  Transmembrane protein 245 (TMEM245) 57.3
 LDTP04770  Syntaxin-17 (STX17) 56.9
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 56.5
 LDTP11615  Protein tweety homolog 3 (TTYH3) 56.5
 LDTP04849  CD81 antigen (CD81) 56.1
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 55.3
 LDTP12979  Transmembrane protein 14C (TMEM14C) 55.3
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 54.9
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 54.9
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 54.9
 LDTP11406  Transmembrane protein 59 (TMEM59) 54.6
 LDTP02655  Lysosome-associated membrane glycoprotein 2 (LAMP2) 54.2
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 54.2
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 53.8
 LDTP01060  PRA1 family protein 2 (PRAF2) 53.4
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 53.1
 LDTP01454  SUN domain-containing protein 1 (SUN1) 53.1
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 53.1
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 52.7
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 52.0
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 52.0
 LDTP08469  Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) 51.6
 LDTP13142  Vacuolar protein sorting-associated protein 29 (VPS29) 51.3
 LDTP09180  Zinc transporter 7 (SLC30A7) 51.3
 LDTP13953  Endophilin-B1 (SH3GLB1) 50.6
 LDTP11732  Magnesium transporter protein 1 (MAGT1) 50.6
 LDTP11634  Derlin-2 (DERL2) 50.2
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 50.2
 LDTP00592  Surfeit locus protein 4 (SURF4) 50.2
 LDTP01160  Peroxisomal membrane protein 11A (PEX11A) 49.5
 LDTP04237  Protein ERGIC-53 (LMAN1) 49.5
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 49.2
 LDTP11116  45 kDa calcium-binding protein (SDF4) 48.5
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 48.5
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 46.9
 LDTP03405  Calnexin (CANX) 46.2
 LDTP14970  Metaxin-3 (MTX3) 45.9
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 45.9
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 45.6
 LDTP06039  Dystroglycan 1 (DAG1) 44.9
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 44.9
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 44.9
 LDTP10343  Vacuole membrane protein 1 (VMP1) 44.9
 LDTP04501  Importin subunit alpha-1 (KPNA2) 44.6
 LDTP12738  Ceroid-lipofuscinosis neuronal protein 6 (CLN6) 44.3
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 44.3
 LDTP03546  Translocator protein (TSPO) 44.3
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 44.0
 LDTP01234  Erlin-1 (ERLIN1) 43.7
 LDTP10769  Intermembrane lipid transfer protein VPS13A (VPS13A) 43.7
 LDTP12451  Integral membrane protein 2C (ITM2C) 43.4
 LDTP05780  Syntaxin-5 (STX5) 43.1
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 42.5
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 42.5
 LDTP11245  Derlin-1 (DERL1) 42.2
 LDTP07531  Sideroflexin-4 (SFXN4) 42.2
 LDTP06271  ER membrane protein complex subunit 2 (EMC2) 40.8
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 40.8
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 40.2
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 40.2
 LDTP13201  Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B) 39.9
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 39.1
 LDTP18053  Probable mitochondrial glutathione transporter SLC25A40 (SLC25A40) 39.1
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 38.9
 LDTP06198  Major facilitator superfamily domain-containing protein 10 (MFSD10) 38.9
 LDTP00970  Gasdermin-E (GSDME) 38.6
 LDTP01309  Renin receptor (ATP6AP2) 38.3
 LDTP01380  Wolframin (WFS1) 38.3
 LDTP04787  Transmembrane protein 33 (TMEM33) 38.1
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 37.8
 LDTP16190  Protein FAM8A1 (FAM8A1) 37.5
 LDTP07667  Transmembrane protein 205 (TMEM205) 37.5
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 37.5
 LDTP09288  Vang-like protein 1 (VANGL1) 37.5
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 37.3
 LDTP08960  ER membrane protein complex subunit 1 (EMC1) 37.0
 LDTP01133  Copine-3 (CPNE3) 36.8
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 36.5
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 36.5
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 36.3
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 36.3
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 36.3
 LDTP00590  Protein RER1 (RER1) 36.3
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 36.3
 LDTP07490  Zinc transporter 6 (SLC30A6) 36.3
 LDTP06331  Pericentriolar material 1 protein (PCM1) 35.8
 LDTP04259  Signal recognition particle 9 kDa protein (SRP9) 35.8
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 36.5
Immunoglobulin
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 56.5
 LDTP03772  Basigin (BSG) 48.8
 LDTP04720  IgG receptor FcRn large subunit p51 (FCGRT) 42.8
 LDTP03538  HLA class I histocompatibility antigen, alpha chain F (HLA-F) 40.8
 LDTP14205  Neuroplastin (NPTN) 37.8
Other
Click to Show/Hide to Show 153 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11076  Apolipoprotein L2 (APOL2) 99.7
 LDTP03926  Centrin-2 (CETN2) 99.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 99.7
 LDTP01359  Dynactin subunit 3 (DCTN3) 99.7
 LDTP10783  Gamma-tubulin complex component 6 (TUBGCP6) 99.7
 LDTP12891  Glycolipid transfer protein (GLTP) 99.7
 LDTP07406  GRAM domain-containing protein 4 (GRAMD4) 99.7
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 99.7
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 99.7
 LDTP14939  Membralin (TMEM259) 99.7
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP05160  Nucleobindin-2 (NUCB2) 99.7
 LDTP18883  Protein CEBPZOS (CEBPZOS) 99.7
 LDTP10056  Protein FAM162A (FAM162A) 99.7
 LDTP15793  Protein FAM210A (FAM210A) 99.7
 LDTP06948  Protein YIF1B (YIF1B) 99.7
 LDTP01167  Reticulon-2 (RTN2) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP12412  Reticulon-4 (RTN4) 99.7
 LDTP19859  Small integral membrane protein 12 (SMIM12) 99.7
 LDTP13086  Syntaxin-18 (STX18) 99.7
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 99.7
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 99.7
 LDTP19033  Uncharacterized protein C6orf47 (C6orf47) 99.7
 LDTP19963  TraB domain-containing protein (TRABD) 97.0
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 95.0
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 92.4
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 92.4
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 91.8
 LDTP00986  Syntaxin-10 (STX10) 90.5
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 88.0
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 88.0
 LDTP15634  Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) 86.8
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 85.6
 LDTP14126  Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) 84.4
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 83.9
 LDTP15741  Cytochrome c oxidase assembly protein COX14 (COX14) 83.3
 LDTP09773  Protein FAM3C (FAM3C) 79.3
 LDTP08320  Ankyrin repeat domain-containing protein 46 (ANKRD46) 77.7
 LDTP16006  Optic atrophy 3 protein (OPA3) 77.7
 LDTP16080  Protein FAM114A2 (FAM114A2) 76.1
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 76.1
 LDTP04356  Emerin (EMD) 75.1
 LDTP11167  Protein YIPF4 (YIPF4) 72.0
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 71.5
 LDTP08224  Protein LYRIC (MTDH) 71.0
 LDTP14458  Tetraspanin-6 (TSPAN6) 71.0
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 71.0
 LDTP13797  HIG1 domain family member 1A, mitochondrial (HIGD1A) 70.0
 LDTP10924  Prohibitin-2 (PHB2) 69.6
 LDTP01494  Protein YIF1A (YIF1A) 68.6
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 68.1
 LDTP18462  COX assembly mitochondrial protein 2 homolog (CMC2) 68.1
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 67.6
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 66.7
 LDTP05375  Nucleobindin-1 (NUCB1) 65.8
 LDTP06097  Reticulocalbin-2 (RCN2) 65.8
 LDTP14259  Testis-expressed protein 264 (TEX264) 65.8
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 64.9
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 64.9
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 64.0
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 63.6
 LDTP08606  Nurim (NRM) 62.2
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 61.4
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 60.1
 LDTP00871  Microtubule nucleation factor SSNA1 (SSNA1) 59.7
 LDTP09080  Reticulophagy regulator 2 (RETREG2) 58.5
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 58.1
 LDTP10093  Mitochondrial calcium uniporter regulator 1 (MCUR1) 57.7
 LDTP12287  Ran guanine nucleotide release factor (RANGRF) 56.9
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 56.5
 LDTP19860  Coiled-coil domain-containing protein 97 (CCDC97) 56.1
 LDTP04875  Myosin light polypeptide 6 (MYL6) 56.1
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 55.3
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 54.9
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 54.9
 LDTP15434  ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) 54.2
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 54.2
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 53.8
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 53.4
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 53.1
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 52.3
 LDTP10207  Mitochondrial import inner membrane translocase subunit TIM14 (DNAJC19) 52.3
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 52.0
 LDTP00223  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) 51.6
 LDTP08902  CDGSH iron-sulfur domain-containing protein 2 (CISD2) 51.3
 LDTP16577  DENN domain-containing protein 11 (DENND11) 51.3
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 51.3
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 50.9
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 50.2
 LDTP15398  Protein FAM177A1 (FAM177A1) 50.2
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 49.9
 LDTP16116  BSD domain-containing protein 1 (BSDC1) 49.5
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 49.5
 LDTP02297  Vimentin (VIM) 49.2
 LDTP15944  Cytochrome c oxidase assembly factor 1 homolog (COA1) 48.8
 LDTP00859  Synaptogyrin-2 (SYNGR2) 48.8
 LDTP10908  Protein S100-A13 (S100A13) 47.8
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 46.9
 LDTP10275  Mitochondrial potassium channel (CCDC51) 46.2
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 45.6
 LDTP16285  Transducin beta-like protein 2 (TBL2) 45.6
 LDTP15253  HEAT repeat-containing protein 3 (HEATR3) 44.9
 LDTP03729  General transcription factor IIF subunit 1 (GTF2F1) 44.0
 LDTP20361  Coiled-coil domain-containing protein 127 (CCDC127) 43.7
 LDTP16099  p53 and DNA damage-regulated protein 1 (PDRG1) 43.1
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 42.5
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 42.2
 LDTP01582  Pre-mRNA-splicing factor SLU7 (SLU7) 42.2
 LDTP09644  m-AAA protease-interacting protein 1, mitochondrial (MAIP1) 41.9
 LDTP13982  Mitochondrial fission 1 protein (FIS1) 41.9
 LDTP11044  Polyadenylate-binding protein-interacting protein 2 (PAIP2) 41.6
 LDTP04917  Proteasome activator complex subunit 3 (PSME3) 41.6
 LDTP16250  Translocon-associated protein subunit gamma (SSR3) 41.6
 LDTP10799  GPI transamidase component PIG-S (PIGS) 41.4
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 41.4
 LDTP18467  LYR motif-containing protein 2 (LYRM2) 41.1
 LDTP08300  Reticulophagy regulator 3 (RETREG3) 40.5
 LDTP17652  Uncharacterized protein KIAA2013 (KIAA2013) 40.2
 LDTP10469  Engulfment and cell motility protein 2 (ELMO2) 39.9
 LDTP12545  Protein kish-B (TMEM167B) 39.9
 LDTP13913  Inner nuclear membrane protein Man1 (LEMD3) 39.7
 LDTP01286  Centriole and centriolar satellite protein OFD1 (OFD1) 39.4
 LDTP10403  DDRGK domain-containing protein 1 (DDRGK1) 39.4
 LDTP00632  Syntaxin-7 (STX7) 39.4
 LDTP02351  Tropomyosin alpha-1 chain (TPM1) 39.4
 LDTP14164  Immediate early response 3-interacting protein 1 (IER3IP1) 39.1
 LDTP08153  Transmembrane emp24 domain-containing protein 4 (TMED4) 38.9
 LDTP06527  Alpha-internexin (INA) 38.6
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 38.3
 LDTP09787  Nicastrin (NCSTN) 38.1
 LDTP05277  Protein SET (SET) 38.1
 LDTP14443  Small ribosomal subunit protein uS12m (MRPS12) 38.1
 LDTP00759  Tumor protein D54 (TPD52L2) 38.1
 LDTP02180  Neurofilament light polypeptide (NEFL) 37.8
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 37.8
 LDTP01661  Synaptosomal-associated protein 29 (SNAP29) 37.5
 LDTP18272  Transmembrane protein 209 (TMEM209) 37.5
 LDTP10255  Protein Hook homolog 2 (HOOK2) 37.3
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 37.0
 LDTP00417  Programmed cell death protein 5 (PDCD5) 37.0
 LDTP04304  Translation initiation factor eIF2B subunit beta (EIF2B2) 37.0
 LDTP04703  Tumor protein D52 (TPD52) 37.0
 LDTP13519  Proteasome activator complex subunit 2 (PSME2) 36.8
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 36.5
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 36.3
 LDTP08081  Hepatoma-derived growth factor-related protein 2 (HDGFL2) 36.3
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 36.0
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 36.0
 LDTP00555  BET1 homolog (BET1) 35.8
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 35.8

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587