Details of the Probe

General Information of Probe

Probe ID
LDPC0409
Probe Name
C169
Synonyms
Z4225935140
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 322.4
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C19H22N4O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-3-(4-methyl-1H-indol-3-yl)propanamide
Canonical SMILES
CC1=C2C(=CC=C1)NC=C2CCC(=O)NCCC3(N=N3)CCC#C
InChI
InChI=1S/C19H22N4O/c1-3-4-10-19(22-23-19)11-12-20-17(24)9-8-15-13-21-16-7-5-6-14(2)18(15)16/h1,5-7,13,21H,4,8-12H2,2H3,(H,20,24)
InChIKey
XERKRMOLNNBSEO-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

137 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 24.08  LDD1849 
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3) LDTP15132 85.04  LDD1849 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 25.63  LDD1849 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 25.99  LDD1849 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 20.97  LDD1849 
Acyl-coenzyme A diphosphatase NUDT19 (NUDT19) LDTP00150 20.53  LDD1849 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 21.86  LDD1849 
Adenosine deaminase (ADA) LDTP01803 39.95  LDD1849 
Adenylate cyclase type 3 (ADCY3) LDTP00932 21.71  LDD1849 
ADP-dependent glucokinase (ADPGK) LDTP11127 51.27  LDD1849 
ADP-ribosylation factor-like protein 1 (ARL1) LDTP03900 33.82  LDD1849 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 51.63  LDD1849 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 36.50  LDD1849 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 20.68  LDD1849 
Atlastin-2 (ATL2) LDTP09251 22.16  LDD1849 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 37.53  LDD1849 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 20.53  LDD1849 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 21.11  LDD1849 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 23.43  LDD1849 
Beta-1,4-galactosyltransferase 3 (B4GALT3) LDTP00994 26.35  LDD1849 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 93.70  LDD1849 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 40.50  LDD1849 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 22.32  LDD1849 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 99.73  LDD1849 
Catechol O-methyltransferase (COMT) LDTP03145 45.57  LDD1849 
Ceramide glucosyltransferase (UGCG) LDTP06617 61.39  LDD1849 
Ceramide synthase 1 (CERS1) LDTP03394 34.54  LDD1849 
Ceramide synthase 2 (CERS2) LDTP10329 26.54  LDD1849 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 22.16  LDD1849 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 49.52  LDD1849 
Cullin-1 (CUL1) LDTP05946 40.50  LDD1849 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 82.71  LDD1849 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1849 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 27.47  LDD1849 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 83.29  LDD1849 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 19.84  LDD1849 
Delta(24)-sterol reductase (DHCR24) LDTP06375 28.84  LDD1849 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 23.26  LDD1849 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 27.86  LDD1849 
Dihydrofolate reductase (DHFR) LDTP01769 23.26  LDD1849 
Dihydroxyacetone phosphate acyltransferase (GNPAT) LDTP00577 26.72  LDD1849 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 21.26  LDD1849 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 58.08  LDD1849 
E3 ubiquitin-protein ligase NEDD4 (NEDD4) LDTP04114 23.10  LDD1849 
E3 ubiquitin-protein ligase SHPRH (SHPRH) LDTP06253 53.08  LDD1849 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 36.50  LDD1849 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 20.11  LDD1849 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 25.46  LDD1849 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 47.18  LDD1849 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 31.56  LDD1849 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 20.97  LDD1849 
Glutathione hydrolase 7 (GGT7) LDTP13367 25.63  LDD1849 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 20.39  LDD1849 
Glycerophosphodiester phosphodiesterase 1 (GDE1) LDTP12886 20.97  LDD1849 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 20.39  LDD1849 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 24.76  LDD1849 
Heme A synthase COX15 (COX15) LDTP07931 44.02  LDD1849 
Heme oxygenase 1 (HMOX1) LDTP02359 60.13  LDD1849 
Heme oxygenase 2 (HMOX2) LDTP03540 99.73  LDD1849 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 25.99  LDD1849 
Hexokinase-2 (HK2) LDTP04531 21.71  LDD1849 
Holocytochrome c-type synthase (HCCS) LDTP04581 49.87  LDD1849 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 58.08  LDD1849 
Lactoylglutathione lyase (GLO1) LDTP05434 22.47  LDD1849 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 99.73  LDD1849 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 23.59  LDD1849 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 46.53  LDD1849 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 48.84  LDD1849 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 24.59  LDD1849 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 27.86  LDD1849 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 30.91  LDD1849 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 29.65  LDD1849 
Minor histocompatibility antigen H13 (HM13) LDTP09396 29.86  LDD1849 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 20.11  LDD1849 
Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) LDTP06810 22.63  LDD1849 
Mitofusin-1 (MFN1) LDTP08530 20.68  LDD1849 
Mitogen-activated protein kinase kinase kinase 4 (MAP3K4) LDTP14291 23.10  LDD1849 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 42.52  LDD1849 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 46.53  LDD1849 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 21.26  LDD1849 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 21.26  LDD1849 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 38.59  LDD1849 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 21.56  LDD1849 
NADH dehydrogenase 1 alpha subcomplex subunit 8 (NDUFA8) LDTP04494 20.82  LDD1849 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 33.13  LDD1849 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 91.14  LDD1849 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 57.68  LDD1849 
NADPH--cytochrome P450 reductase (POR) LDTP02848 27.86  LDD1849 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 20.82  LDD1849 
Outer mitochondrial transmembrane helix translocase (ATAD1) LDTP09070 23.43  LDD1849 
Pachytene checkpoint protein 2 homolog (TRIP13) LDTP06432 31.34  LDD1849 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 29.45  LDD1849 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 37.79  LDD1849 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 29.86  LDD1849 
Peptidyl-prolyl cis-trans isomerase FKBP2 (FKBP2) LDTP03374 99.73  LDD1849 
Peptidyl-prolyl cis-trans isomerase FKBP3 (FKBP3) LDTP05255 24.25  LDD1849 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 47.18  LDD1849 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 26.91  LDD1849 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 33.36  LDD1849 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 30.91  LDD1849 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 21.41  LDD1849 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 61.82  LDD1849 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 29.45  LDD1849 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 21.71  LDD1849 
Prostaglandin reductase 3 (PTGR3) LDTP15422 20.68  LDD1849 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 20.25  LDD1849 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 24.93  LDD1849 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 19.84  LDD1849 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 36.76  LDD1849 
Rab-like protein 3 (RABL3) LDTP06986 20.11  LDD1849 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 23.10  LDD1849 
Ras-related protein Rab-1B (RAB1B) LDTP11733 19.84  LDD1849 
Ras-related protein Rab-24 (RAB24) LDTP10020 26.91  LDD1849 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 42.22  LDD1849 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 27.67  LDD1849 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 28.05  LDD1849 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 56.49  LDD1849 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 23.10  LDD1849 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 23.10  LDD1849 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 23.43  LDD1849 
Sphingosine kinase 2 (SPHK2) LDTP12490 36.00  LDD1849 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 42.22  LDD1849 
Squalene monooxygenase (SQLE) LDTP06142 26.54  LDD1849 
Squalene synthase (FDFT1) LDTP03842 30.70  LDD1849 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 25.81  LDD1849 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 20.68  LDD1849 
TLC domain-containing protein 1 (TLCD1) LDTP10182 32.00  LDD1849 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 35.02  LDD1849 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 25.46  LDD1849 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 31.34  LDD1849 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 30.27  LDD1849 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 20.82  LDD1849 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 55.72  LDD1849 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 20.97  LDD1849 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 99.73  LDD1849 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 24.93  LDD1849 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 34.78  LDD1849 
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⏷ Show the Full List of 137 Enzyme
97 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 24.42  LDD1849 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 31.56  LDD1849 
Anoctamin-10 (ANO10) LDTP12704 31.56  LDD1849 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 45.25  LDD1849 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 30.91  LDD1849 
BOS complex subunit NCLN (NCLN) LDTP10036 86.22  LDD1849 
Cell division cycle protein 20 homolog (CDC20) LDTP05662 20.97  LDD1849 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 24.93  LDD1849 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 23.43  LDD1849 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 30.27  LDD1849 
Derlin-1 (DERL1) LDTP11245 32.67  LDD1849 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 89.88  LDD1849 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.04  LDD1849 
Eukaryotic translation initiation factor 4E transporter (EIF4ENIF1) LDTP12493 20.53  LDD1849 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 40.50  LDD1849 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 19.84  LDD1849 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 22.63  LDD1849 
Guided entry of tail-anchored proteins factor CAMLG (CAMLG) LDTP04227 28.05  LDD1849 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 22.94  LDD1849 
Integral membrane protein 2B (ITM2B) LDTP13833 29.45  LDD1849 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 21.71  LDD1849 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 35.02  LDD1849 
Lysosome membrane protein 2 (SCARB2) LDTP06034 34.06  LDD1849 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 20.39  LDD1849 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 21.41  LDD1849 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 43.41  LDD1849 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 47.84  LDD1849 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 34.06  LDD1849 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 91.14  LDD1849 
Metaxin-1 (MTX1) LDTP05900 63.56  LDD1849 
MICOS complex subunit MIC26 (APOO) LDTP11250 21.71  LDD1849 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 24.76  LDD1849 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 29.65  LDD1849 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 32.00  LDD1849 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 51.98  LDD1849 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 30.27  LDD1849 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 98.36  LDD1849 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 30.70  LDD1849 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 19.97  LDD1849 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 38.05  LDD1849 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 27.28  LDD1849 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 53.45  LDD1849 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 25.28  LDD1849 
Mpv17-like protein 2 (MPV17L2) LDTP14952 28.44  LDD1849 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 22.94  LDD1849 
Nucleoporin NDC1 (NDC1) LDTP11213 24.42  LDD1849 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 34.78  LDD1849 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 40.50  LDD1849 
PRA1 family protein 2 (PRAF2) LDTP01060 28.84  LDD1849 
Prosaposin (PSAP) LDTP02215 27.67  LDD1849 
Protein ARV1 (ARV1) LDTP11812 56.10  LDD1849 
Protein GPR107 (GPR107) LDTP07236 29.65  LDD1849 
Protein GPR108 (GPR108) LDTP12383 24.59  LDD1849 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 24.59  LDD1849 
Protein tweety homolog 3 (TTYH3) LDTP11615 29.65  LDD1849 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 35.26  LDD1849 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 39.67  LDD1849 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 23.75  LDD1849 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 27.47  LDD1849 
Sideroflexin-4 (SFXN4) LDTP07531 29.86  LDD1849 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 20.53  LDD1849 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 29.65  LDD1849 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 36.00  LDD1849 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 20.97  LDD1849 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 22.47  LDD1849 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 30.70  LDD1849 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 73.52  LDD1849 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 25.81  LDD1849 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 22.78  LDD1849 
Stromal interaction molecule 1 (STIM1) LDTP05934 25.11  LDD1849 
Sugar phosphate exchanger 3 (SLC37A3) LDTP09089 27.47  LDD1849 
Surfeit locus protein 4 (SURF4) LDTP00592 35.75  LDD1849 
Syntaxin-5 (STX5) LDTP05780 29.65  LDD1849 
Syntaxin-6 (STX6) LDTP00857 42.81  LDD1849 
Tetraspanin-3 (TSPAN3) LDTP16813 30.06  LDD1849 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 69.07  LDD1849 
Translocator protein (TSPO) LDTP03546 30.48  LDD1849 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1849 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 25.46  LDD1849 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 39.67  LDD1849 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 20.68  LDD1849 
Transmembrane protein 106B (TMEM106B) LDTP12635 21.41  LDD1849 
Transmembrane protein 160 (TMEM160) LDTP20002 37.53  LDD1849 
Transmembrane protein 199 (TMEM199) LDTP08881 48.17  LDD1849 
Transmembrane protein 201 (TMEM201) LDTP07058 21.56  LDD1849 
Transmembrane protein 205 (TMEM205) LDTP07667 28.25  LDD1849 
Transmembrane protein 230 (TMEM230) LDTP10065 25.46  LDD1849 
Transmembrane protein 245 (TMEM245) LDTP15979 42.22  LDD1849 
Transmembrane protein 59 (TMEM59) LDTP11406 97.01  LDD1849 
Transmembrane protein 65 (TMEM65) LDTP07583 25.63  LDD1849 
Transmembrane protein 87A (TMEM87A) LDTP15481 55.72  LDD1849 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 27.67  LDD1849 
Vacuole membrane protein 1 (VMP1) LDTP10343 21.26  LDD1849 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 99.73  LDD1849 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 99.73  LDD1849 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 35.51  LDD1849 
Wolframin (WFS1) LDTP01380 23.75  LDD1849 
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⏷ Show the Full List of 97 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 46.21  LDD1849 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 21.11  LDD1849 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 19.97  LDD1849 
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88 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 19.84  LDD1849 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 25.11  LDD1849 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1849 
BAG family molecular chaperone regulator 5 (BAG5) LDTP13507 20.53  LDD1849 
Beta-2-syntrophin (SNTB2) LDTP05864 29.86  LDD1849 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 20.53  LDD1849 
Centrin-2 (CETN2) LDTP03926 30.27  LDD1849 
Clustered mitochondria protein homolog (CLUH) LDTP14486 27.28  LDD1849 
Coiled-coil domain-containing protein 97 (CCDC97) LDTP19860 29.04  LDD1849 
Collectin-12 (COLEC12) LDTP07031 24.08  LDD1849 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 23.59  LDD1849 
Conserved oligomeric Golgi complex subunit 3 (COG3) LDTP10452 22.94  LDD1849 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD1849 
Dedicator of cytokinesis protein 1 (DOCK1) LDTP06072 19.84  LDD1849 
DET1- and DDB1-associated protein 1 (DDA1) LDTP11312 43.11  LDD1849 
Dymeclin (DYM) LDTP08000 20.25  LDD1849 
Dynactin subunit 3 (DCTN3) LDTP01359 22.16  LDD1849 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 22.94  LDD1849 
Emerin (EMD) LDTP04356 26.17  LDD1849 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 99.73  LDD1849 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1849 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 33.13  LDD1849 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 27.86  LDD1849 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 32.90  LDD1849 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 20.11  LDD1849 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 22.94  LDD1849 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 23.43  LDD1849 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 23.43  LDD1849 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 29.45  LDD1849 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 22.78  LDD1849 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 21.11  LDD1849 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 50.21  LDD1849 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 24.93  LDD1849 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 50.91  LDD1849 
Leukocyte receptor cluster member 8 (LENG8) LDTP10703 48.84  LDD1849 
Lipase maturation factor 2 (LMF2) LDTP15887 22.01  LDD1849 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 28.05  LDD1849 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 27.28  LDD1849 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 35.75  LDD1849 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 42.52  LDD1849 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 60.55  LDD1849 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1849 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1849 
Negative elongation factor C/D (NELFCD) LDTP08594 22.16  LDD1849 
Nidogen-1 (NID1) LDTP02728 23.92  LDD1849 
NLR family member X1 (NLRX1) LDTP08248 24.25  LDD1849 
Nucleobindin-1 (NUCB1) LDTP05375 54.19  LDD1849 
Nucleobindin-2 (NUCB2) LDTP05160 87.43  LDD1849 
Nurim (NRM) LDTP08606 52.35  LDD1849 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 30.06  LDD1849 
Optic atrophy 3 protein (OPA3) LDTP16006 91.14  LDD1849 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 49.87  LDD1849 
Pre-mRNA-splicing factor SPF27 (BCAS2) LDTP01358 25.11  LDD1849 
Prohibitin-2 (PHB2) LDTP10924 20.97  LDD1849 
Protein CEBPZOS (CEBPZOS) LDTP18883 22.94  LDD1849 
Protein CREG1 (CREG1) LDTP01279 22.94  LDD1849 
Protein CUSTOS (CUSTOS) LDTP18134 22.47  LDD1849 
Protein FAM114A2 (FAM114A2) LDTP16080 28.44  LDD1849 
Protein FAM162A (FAM162A) LDTP10056 28.84  LDD1849 
Protein FAM177A1 (FAM177A1) LDTP15398 23.26  LDD1849 
Protein FAM3C (FAM3C) LDTP09773 29.04  LDD1849 
Protein Hikeshi (HIKESHI) LDTP06892 19.97  LDD1849 
Protein jagunal homolog 1 (JAGN1) LDTP08904 24.76  LDD1849 
Protein LYRIC (MTDH) LDTP08224 26.54  LDD1849 
Protein unc-119 homolog B (UNC119B) LDTP00105 32.67  LDD1849 
Protein UXT (UXT) LDTP13125 23.59  LDD1849 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 28.84  LDD1849 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 32.00  LDD1849 
Reticulon-2 (RTN2) LDTP01167 27.86  LDD1849 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1849 
Reticulon-4 (RTN4) LDTP12412 36.76  LDD1849 
RUS family member 1 (RUSF1) LDTP10357 24.93  LDD1849 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 34.54  LDD1849 
Synaptogyrin-2 (SYNGR2) LDTP00859 37.53  LDD1849 
Synaptosomal-associated protein 47 (SNAP47) LDTP07061 22.01  LDD1849 
Syntaxin-18 (STX18) LDTP13086 97.68  LDD1849 
Testis-expressed protein 264 (TEX264) LDTP14259 35.02  LDD1849 
Tetraspanin-6 (TSPAN6) LDTP14458 30.70  LDD1849 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 60.13  LDD1849 
TraB domain-containing protein (TRABD) LDTP19963 29.24  LDD1849 
Transducin beta-like protein 2 (TBL2) LDTP16285 23.43  LDD1849 
Translocon-associated protein subunit delta (SSR4) LDTP04425 20.68  LDD1849 
Transmembrane protein 209 (TMEM209) LDTP18272 23.59  LDD1849 
Transmembrane protein 98 (TMEM98) LDTP13932 22.47  LDD1849 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 85.04  LDD1849 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 21.26  LDD1849 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 36.00  LDD1849 
Vimentin (VIM) LDTP02297 20.11  LDD1849 
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⏷ Show the Full List of 88 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1849 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587