Details of the Target

General Information of Target

Target ID LDTP07061
Target Name Synaptosomal-associated protein 47 (SNAP47)
Gene Name SNAP47
Gene ID 116841
Synonyms
C1orf142; HEL170; SVAP1; Synaptosomal-associated protein 47; SNAP-47; Epididymis luminal protein 170; Synaptosomal-associated 47 kDa protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRAARRGLHCAGAERPRRRGRLWDSSGVPQRQKRPGPWRTQTQEQMSRDVCIHTWPCTYY
LEPKRRWVTGQLSLTSLSLRFMTDSTGEILVSFPLSSIVEIKKEASHFIFSSITILEKGH
AKHWFSSLRPSRNVVFSIIEHFWRELLLSQPGAVADASVPRTRGEELTGLMAGSQKRLED
TARVLHHQGQQLDSVMRGLDKMESDLEVADRLLTELESPAWWPFSSKLWKTPPETKPRED
VSMTSCEPFGKEGILIKIPAVISHRTESHVKPGRLTVLVSGLEIHDSSSLLMHRFEREDV
DDIKVHSPYEISIRQRFIGKPDMAYRLISAKMPEVIPILEVQFSKKMELLEDALVLRSAR
TSSPAEKSCSVWHAASGLMGRTLHREPPAGDQEGTALHLQTSLPALSEADTQELTQILRR
MKGLALEAESELERQDEALDGVAAAVDRATLTIDKHNRRMKRLT
Target Bioclass
Other
Family
SVAP1 family
Subcellular location
Endomembrane system
Function Plays a role in intracellular membrane fusion.
Uniprot ID
Q5SQN1
Ensemble ID
ENST00000366760.5
HGNC ID
HGNC:30669

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K455(10.00)  LDD0277  [1]
DA-P3
 Probe Info  		6.31  LDD0179  [2]
DBIA
 Probe Info  		C51(0.96); C57(0.96)  LDD0078  [3]
IPM
 Probe Info  		C246(0.00); C369(0.00)  LDD2156  [4]
VSF
 Probe Info  		N.A.  LDD0007  [5]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [6]
AOyne
 Probe Info  		15.00  LDD0443  [7]
PAL-AfBPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C169
 Probe Info  		22.01  LDD1849  [8]
C278
 Probe Info  		55.72  LDD1948  [8]
C284
 Probe Info  		21.26  LDD1954  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C51(0.90); C57(0.90)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C51(1.03); C57(1.03)  LDD0532  [3]
 LDCM0216  AC100 HEK-293T C51(0.83); C57(0.83)  LDD0814  [3]
 LDCM0217  AC101 HEK-293T C51(0.84); C57(0.84)  LDD0815  [3]
 LDCM0218  AC102 HEK-293T C51(0.81); C57(0.81)  LDD0816  [3]
 LDCM0219  AC103 HEK-293T C51(0.88); C57(0.88)  LDD0817  [3]
 LDCM0220  AC104 HEK-293T C51(0.98); C57(0.98)  LDD0818  [3]
 LDCM0221  AC105 HEK-293T C51(0.80); C57(0.80)  LDD0819  [3]
 LDCM0222  AC106 HEK-293T C51(0.81); C57(0.81)  LDD0820  [3]
 LDCM0223  AC107 HEK-293T C51(0.89); C57(0.89)  LDD0821  [3]
 LDCM0224  AC108 HEK-293T C51(0.76); C57(0.76)  LDD0822  [3]
 LDCM0225  AC109 HEK-293T C51(0.84); C57(0.84)  LDD0823  [3]
 LDCM0226  AC11 HCT 116 C51(0.89); C57(0.89)  LDD0543  [3]
 LDCM0227  AC110 HEK-293T C51(0.99); C57(0.99)  LDD0825  [3]
 LDCM0228  AC111 HEK-293T C51(0.88); C57(0.88)  LDD0826  [3]
 LDCM0229  AC112 HEK-293T C51(0.85); C57(0.85)  LDD0827  [3]
 LDCM0230  AC113 HEK-293T C51(0.94); C57(0.94)  LDD0828  [3]
 LDCM0231  AC114 HEK-293T C51(0.85); C57(0.85)  LDD0829  [3]
 LDCM0232  AC115 HEK-293T C51(0.86); C57(0.86)  LDD0830  [3]
 LDCM0233  AC116 HEK-293T C51(1.00); C57(1.00)  LDD0831  [3]
 LDCM0234  AC117 HEK-293T C51(0.96); C57(0.96)  LDD0832  [3]
 LDCM0235  AC118 HEK-293T C51(0.90); C57(0.90)  LDD0833  [3]
 LDCM0236  AC119 HEK-293T C51(0.88); C57(0.88)  LDD0834  [3]
 LDCM0237  AC12 HCT 116 C51(1.15); C57(1.15)  LDD0554  [3]
 LDCM0238  AC120 HEK-293T C51(0.78); C57(0.78)  LDD0836  [3]
 LDCM0239  AC121 HEK-293T C51(0.93); C57(0.93)  LDD0837  [3]
 LDCM0240  AC122 HEK-293T C51(0.88); C57(0.88)  LDD0838  [3]
 LDCM0241  AC123 HEK-293T C51(0.91); C57(0.91)  LDD0839  [3]
 LDCM0242  AC124 HEK-293T C51(0.98); C57(0.98)  LDD0840  [3]
 LDCM0243  AC125 HEK-293T C51(0.89); C57(0.89)  LDD0841  [3]
 LDCM0244  AC126 HEK-293T C51(0.96); C57(0.96)  LDD0842  [3]
 LDCM0245  AC127 HEK-293T C51(0.93); C57(0.93)  LDD0843  [3]
 LDCM0246  AC128 HEK-293T C51(0.88); C57(0.88)  LDD0844  [3]
 LDCM0247  AC129 HEK-293T C51(1.06); C57(1.06)  LDD0845  [3]
 LDCM0249  AC130 HEK-293T C51(1.39); C57(1.39)  LDD0847  [3]
 LDCM0250  AC131 HEK-293T C51(1.11); C57(1.11)  LDD0848  [3]
 LDCM0251  AC132 HEK-293T C51(0.89); C57(0.89)  LDD0849  [3]
 LDCM0252  AC133 HEK-293T C51(1.01); C57(1.01)  LDD0850  [3]
 LDCM0253  AC134 HEK-293T C51(1.34); C57(1.34)  LDD0851  [3]
 LDCM0254  AC135 HEK-293T C51(1.10); C57(1.10)  LDD0852  [3]
 LDCM0255  AC136 HEK-293T C51(1.06); C57(1.06)  LDD0853  [3]
 LDCM0256  AC137 HEK-293T C51(0.77); C57(0.77)  LDD0854  [3]
 LDCM0257  AC138 HEK-293T C51(1.00); C57(1.00)  LDD0855  [3]
 LDCM0258  AC139 HEK-293T C51(1.22); C57(1.22)  LDD0856  [3]
 LDCM0259  AC14 HCT 116 C51(0.81); C57(0.81)  LDD0576  [3]
 LDCM0260  AC140 HEK-293T C51(1.05); C57(1.05)  LDD0858  [3]
 LDCM0261  AC141 HEK-293T C51(0.98); C57(0.98)  LDD0859  [3]
 LDCM0262  AC142 HEK-293T C51(0.87); C57(0.87)  LDD0860  [3]
 LDCM0263  AC143 HCT 116 C51(0.76); C57(0.76)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C51(0.56); C57(0.56)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C51(0.39); C57(0.39)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C51(0.44); C57(0.44)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C51(0.60); C57(0.60)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C51(0.47); C57(0.47)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C51(0.43); C57(0.43)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C51(1.03); C57(1.03)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C51(0.57); C57(0.57)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C51(0.42); C57(0.42)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C51(0.41); C57(0.41)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C51(0.58); C57(0.58)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C51(0.50); C57(0.50)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C51(0.50); C57(0.50)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C51(0.65); C57(0.65)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C51(0.78); C57(0.78)  LDD2161  [3]
 LDCM0276  AC17 HEK-293T C51(1.70)  LDD0874  [3]
 LDCM0277  AC18 HEK-293T C51(1.55)  LDD0875  [3]
 LDCM0278  AC19 HEK-293T C51(1.46)  LDD0876  [3]
 LDCM0279  AC2 HCT 116 C51(0.95); C57(0.95)  LDD0596  [3]
 LDCM0280  AC20 HEK-293T C51(1.74)  LDD0878  [3]
 LDCM0281  AC21 HEK-293T C51(1.32)  LDD0879  [3]
 LDCM0282  AC22 HEK-293T C51(1.97)  LDD0880  [3]
 LDCM0283  AC23 HEK-293T C51(2.03)  LDD0881  [3]
 LDCM0284  AC24 HEK-293T C51(1.49)  LDD0882  [3]
 LDCM0285  AC25 HCT 116 C51(1.13); C57(1.13)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C51(1.21); C57(1.21)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C51(1.30); C57(1.30)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C51(3.13); C57(3.13)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C51(0.85); C57(0.85)  LDD0606  [3]
 LDCM0290  AC3 HCT 116 C51(0.87); C57(0.87)  LDD0607  [3]
 LDCM0291  AC30 HCT 116 C51(1.00); C57(1.00)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C51(1.39); C57(1.39)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C51(1.27); C57(1.27)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C51(1.46); C57(1.46)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C51(1.33); C57(1.33)  LDD0612  [3]
 LDCM0296  AC35 HEK-293T C51(0.81); C57(0.81)  LDD0894  [3]
 LDCM0297  AC36 HEK-293T C51(0.97); C57(0.97)  LDD0895  [3]
 LDCM0298  AC37 HEK-293T C51(1.12); C57(1.12)  LDD0896  [3]
 LDCM0299  AC38 HEK-293T C51(0.89); C57(0.89)  LDD0897  [3]
 LDCM0300  AC39 HEK-293T C51(0.84); C57(0.84)  LDD0898  [3]
 LDCM0301  AC4 HCT 116 C51(1.00); C57(1.00)  LDD0618  [3]
 LDCM0302  AC40 HEK-293T C51(0.96); C57(0.96)  LDD0900  [3]
 LDCM0303  AC41 HEK-293T C51(0.93); C57(0.93)  LDD0901  [3]
 LDCM0304  AC42 HEK-293T C51(1.16); C57(1.16)  LDD0902  [3]
 LDCM0305  AC43 HEK-293T C51(1.00); C57(1.00)  LDD0903  [3]
 LDCM0306  AC44 HEK-293T C51(1.01); C57(1.01)  LDD0904  [3]
 LDCM0307  AC45 HEK-293T C51(0.92); C57(0.92)  LDD0905  [3]
 LDCM0308  AC46 HEK-293T C51(1.02)  LDD1547  [9]
 LDCM0309  AC47 HEK-293T C369(1.09); C246(0.81); C51(0.92)  LDD1548  [9]
 LDCM0310  AC48 HEK-293T C369(1.18); C246(0.91); C51(0.95)  LDD1549  [9]
 LDCM0311  AC49 HEK-293T C369(0.98); C246(0.95); C51(0.95)  LDD1550  [9]
 LDCM0312  AC5 HCT 116 C51(1.10); C57(1.10)  LDD0629  [3]
 LDCM0313  AC50 HEK-293T C369(1.10); C51(0.98)  LDD1552  [9]
 LDCM0314  AC51 HEK-293T C369(1.05); C246(1.12); C51(0.96)  LDD1553  [9]
 LDCM0315  AC52 HEK-293T C369(1.04); C51(0.89)  LDD1554  [9]
 LDCM0316  AC53 HEK-293T C369(1.00); C246(1.01); C51(0.99)  LDD1555  [9]
 LDCM0317  AC54 HEK-293T C51(0.91)  LDD1556  [9]
 LDCM0318  AC55 HEK-293T C369(1.00); C246(0.85); C51(1.02)  LDD1557  [9]
 LDCM0319  AC56 HEK-293T C369(1.04); C246(0.97); C51(1.14)  LDD1558  [9]
 LDCM0320  AC57 HCT 116 C51(0.54); C57(0.54)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C51(0.69); C57(0.69)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C51(0.65); C57(0.65)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C51(0.86); C57(0.86)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C51(0.62); C57(0.62)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C51(0.53); C57(0.53)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C51(0.63); C57(0.63)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C51(0.53); C57(0.53)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C51(0.66); C57(0.66)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C51(0.70); C57(0.70)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C51(0.65); C57(0.65)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C51(0.57); C57(0.57)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C51(0.74); C57(0.74)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C51(0.93); C57(0.93)  LDD0650  [3]
 LDCM0334  AC7 HCT 116 C51(0.92); C57(0.92)  LDD0651  [3]
 LDCM0335  AC70 HCT 116 C51(0.66); C57(0.66)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C51(0.84); C57(0.84)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C51(0.89); C57(0.89)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C51(1.00); C57(1.00)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C51(0.92); C57(0.92)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C51(0.98); C57(0.98)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C51(0.82); C57(0.82)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C51(0.82); C57(0.82)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C51(0.81); C57(0.81)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C51(0.87); C57(0.87)  LDD0661  [3]
 LDCM0345  AC8 HCT 116 C51(1.03); C57(1.03)  LDD0662  [3]
 LDCM0346  AC80 HCT 116 C51(0.89); C57(0.89)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C51(1.34); C57(1.34)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C51(1.01); C57(1.01)  LDD0665  [3]
 LDCM0349  AC83 HEK-293T C51(0.77); C57(0.77)  LDD0947  [3]
 LDCM0350  AC84 HEK-293T C51(0.82); C57(0.82)  LDD0948  [3]
 LDCM0351  AC85 HEK-293T C51(1.27); C57(1.27)  LDD0949  [3]
 LDCM0352  AC86 HEK-293T C51(0.84); C57(0.84)  LDD0950  [3]
 LDCM0353  AC87 HEK-293T C51(0.87); C57(0.87)  LDD0951  [3]
 LDCM0354  AC88 HEK-293T C51(0.86); C57(0.86)  LDD0952  [3]
 LDCM0355  AC89 HEK-293T C51(0.78); C57(0.78)  LDD0953  [3]
 LDCM0357  AC90 HEK-293T C51(0.75); C57(0.75)  LDD0955  [3]
 LDCM0358  AC91 HEK-293T C51(0.90); C57(0.90)  LDD0956  [3]
 LDCM0359  AC92 HEK-293T C51(0.80); C57(0.80)  LDD0957  [3]
 LDCM0360  AC93 HEK-293T C51(0.54); C57(0.54)  LDD0958  [3]
 LDCM0361  AC94 HEK-293T C51(0.69); C57(0.69)  LDD0959  [3]
 LDCM0362  AC95 HEK-293T C51(0.94); C57(0.94)  LDD0960  [3]
 LDCM0363  AC96 HEK-293T C51(1.06); C57(1.06)  LDD0961  [3]
 LDCM0364  AC97 HEK-293T C51(0.80); C57(0.80)  LDD0962  [3]
 LDCM0365  AC98 HEK-293T C51(1.07); C57(1.07)  LDD0963  [3]
 LDCM0366  AC99 HEK-293T C51(0.86); C57(0.86)  LDD0964  [3]
 LDCM0248  AKOS034007472 HCT 116 C51(0.98); C57(0.98)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C51(1.06); C57(1.06)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C51(1.00); C57(1.00)  LDD0592  [3]
 LDCM0020  ARS-1620 HCC44 C51(0.96); C57(0.96)  LDD0078  [3]
 LDCM0367  CL1 HEK-293T C369(1.00); C51(1.19)  LDD1571  [9]
 LDCM0368  CL10 HEK-293T C51(1.16)  LDD1572  [9]
 LDCM0369  CL100 HCT 116 C51(0.89); C57(0.89)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C51(1.13); C57(1.13)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C51(1.13); C57(1.13)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C51(0.85); C57(0.85)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C51(1.00); C57(1.00)  LDD0690  [3]
 LDCM0374  CL105 HEK-293T C51(1.58)  LDD0972  [3]
 LDCM0375  CL106 HEK-293T C51(1.31)  LDD0973  [3]
 LDCM0376  CL107 HEK-293T C51(1.38)  LDD0974  [3]
 LDCM0377  CL108 HEK-293T C51(1.17)  LDD0975  [3]
 LDCM0378  CL109 HEK-293T C51(1.38)  LDD0976  [3]
 LDCM0379  CL11 HEK-293T C369(0.99); C246(0.92); C51(0.99)  LDD1583  [9]
 LDCM0380  CL110 HEK-293T C51(1.71)  LDD0978  [3]
 LDCM0381  CL111 HEK-293T C51(2.11)  LDD0979  [3]
 LDCM0382  CL112 HCT 116 C51(1.03); C57(1.03)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C51(1.37); C57(1.37)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C51(1.30); C57(1.30)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C51(1.07); C57(1.07)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C51(1.15); C57(1.15)  LDD0703  [3]
 LDCM0387  CL117 HEK-293T C51(1.03); C57(1.03)  LDD0985  [3]
 LDCM0388  CL118 HEK-293T C51(1.19); C57(1.19)  LDD0986  [3]
 LDCM0389  CL119 HEK-293T C51(1.24); C57(1.24)  LDD0987  [3]
 LDCM0390  CL12 HEK-293T C369(1.03); C246(1.00); C51(1.10)  LDD1594  [9]
 LDCM0391  CL120 HEK-293T C51(0.99); C57(0.99)  LDD0989  [3]
 LDCM0392  CL121 HEK-293T C369(0.98); C51(1.29)  LDD1596  [9]
 LDCM0393  CL122 HEK-293T C369(0.94); C246(1.01); C51(0.75)  LDD1597  [9]
 LDCM0394  CL123 HEK-293T C369(1.05); C246(0.93); C51(0.97)  LDD1598  [9]
 LDCM0395  CL124 HEK-293T C369(1.11); C246(0.95); C51(0.87)  LDD1599  [9]
 LDCM0396  CL125 HCT 116 C51(0.88); C57(0.88)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C51(0.62); C57(0.62)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C51(0.59); C57(0.59)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C51(0.83); C57(0.83)  LDD0716  [3]
 LDCM0400  CL13 HEK-293T C369(0.87); C51(1.16)  LDD1604  [9]
 LDCM0401  CL14 HEK-293T C369(1.10); C246(0.99); C51(0.82)  LDD1605  [9]
 LDCM0402  CL15 HEK-293T C369(1.12); C246(1.07); C51(1.46)  LDD1606  [9]
 LDCM0403  CL16 HCT 116 C51(0.93); C57(0.93)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C51(1.02); C57(1.02)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C51(0.67); C57(0.67)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C51(0.90); C57(0.90)  LDD0723  [3]
 LDCM0407  CL2 HEK-293T C369(0.97); C246(1.02); C51(1.10)  LDD1611  [9]
 LDCM0408  CL20 HCT 116 C51(0.74); C57(0.74)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C51(0.84); C57(0.84)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C51(0.83); C57(0.83)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C51(1.01); C57(1.01)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C51(0.72); C57(0.72)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C51(0.76); C57(0.76)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C51(0.79); C57(0.79)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C51(0.89); C57(0.89)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C51(0.87); C57(0.87)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C51(0.86); C57(0.86)  LDD0734  [3]
 LDCM0418  CL3 HEK-293T C369(1.00); C246(0.98); C51(1.16)  LDD1622  [9]
 LDCM0419  CL30 HCT 116 C51(0.94); C57(0.94)  LDD0736  [3]
 LDCM0420  CL31 HEK-293T C51(0.74); C57(0.74)  LDD1018  [3]
 LDCM0421  CL32 HEK-293T C51(0.75); C57(0.75)  LDD1019  [3]
 LDCM0422  CL33 HEK-293T C51(1.05); C57(1.05)  LDD1020  [3]
 LDCM0423  CL34 HEK-293T C51(0.85); C57(0.85)  LDD1021  [3]
 LDCM0424  CL35 HEK-293T C51(0.79); C57(0.79)  LDD1022  [3]
 LDCM0425  CL36 HEK-293T C51(0.84); C57(0.84)  LDD1023  [3]
 LDCM0426  CL37 HEK-293T C51(0.89); C57(0.89)  LDD1024  [3]
 LDCM0428  CL39 HEK-293T C51(0.94); C57(0.94)  LDD1026  [3]
 LDCM0429  CL4 HEK-293T C369(1.16); C246(1.15); C51(1.07)  LDD1633  [9]
 LDCM0430  CL40 HEK-293T C51(0.87); C57(0.87)  LDD1028  [3]
 LDCM0431  CL41 HEK-293T C51(0.78); C57(0.78)  LDD1029  [3]
 LDCM0432  CL42 HEK-293T C51(0.94); C57(0.94)  LDD1030  [3]
 LDCM0433  CL43 HEK-293T C51(0.91); C57(0.91)  LDD1031  [3]
 LDCM0434  CL44 HEK-293T C51(0.89); C57(0.89)  LDD1032  [3]
 LDCM0435  CL45 HEK-293T C51(0.89); C57(0.89)  LDD1033  [3]
 LDCM0436  CL46 HEK-293T C51(0.88); C57(0.88)  LDD1034  [3]
 LDCM0437  CL47 HEK-293T C51(1.21); C57(1.21)  LDD1035  [3]
 LDCM0438  CL48 HEK-293T C51(0.82); C57(0.82)  LDD1036  [3]
 LDCM0439  CL49 HEK-293T C51(0.85); C57(0.85)  LDD1037  [3]
 LDCM0440  CL5 HEK-293T C369(0.99); C246(0.77); C51(1.10)  LDD1644  [9]
 LDCM0441  CL50 HEK-293T C51(1.01); C57(1.01)  LDD1039  [3]
 LDCM0442  CL51 HEK-293T C51(0.92); C57(0.92)  LDD1040  [3]
 LDCM0443  CL52 HEK-293T C51(0.91); C57(0.91)  LDD1041  [3]
 LDCM0444  CL53 HEK-293T C51(0.82); C57(0.82)  LDD1042  [3]
 LDCM0445  CL54 HEK-293T C51(0.91); C57(0.91)  LDD1043  [3]
 LDCM0446  CL55 HEK-293T C51(0.76); C57(0.76)  LDD1044  [3]
 LDCM0447  CL56 HEK-293T C51(0.87); C57(0.87)  LDD1045  [3]
 LDCM0448  CL57 HEK-293T C51(0.81); C57(0.81)  LDD1046  [3]
 LDCM0449  CL58 HEK-293T C51(0.86); C57(0.86)  LDD1047  [3]
 LDCM0450  CL59 HEK-293T C51(0.68); C57(0.68)  LDD1048  [3]
 LDCM0451  CL6 HEK-293T C369(1.08); C51(0.81)  LDD1654  [9]
 LDCM0452  CL60 HEK-293T C51(0.59); C57(0.59)  LDD1050  [3]
 LDCM0453  CL61 HEK-293T C369(1.01); C51(1.10)  LDD1656  [9]
 LDCM0454  CL62 HEK-293T C369(0.95); C246(1.11); C51(1.02)  LDD1657  [9]
 LDCM0455  CL63 HEK-293T C369(0.96); C246(1.05); C51(0.91)  LDD1658  [9]
 LDCM0456  CL64 HEK-293T C369(1.18); C246(0.99); C51(0.81)  LDD1659  [9]
 LDCM0457  CL65 HEK-293T C369(0.93); C246(0.89); C51(1.00)  LDD1660  [9]
 LDCM0458  CL66 HEK-293T C369(0.98); C51(1.04)  LDD1661  [9]
 LDCM0459  CL67 HEK-293T C369(0.99); C246(1.20); C51(1.16)  LDD1662  [9]
 LDCM0460  CL68 HEK-293T C369(0.93); C51(1.15)  LDD1663  [9]
 LDCM0461  CL69 HEK-293T C369(0.97); C246(0.93); C51(1.03)  LDD1664  [9]
 LDCM0462  CL7 HEK-293T C369(1.01); C246(1.17); C51(1.08)  LDD1665  [9]
 LDCM0463  CL70 HEK-293T C51(0.91)  LDD1666  [9]
 LDCM0464  CL71 HEK-293T C369(0.88); C246(0.92); C51(1.01)  LDD1667  [9]
 LDCM0465  CL72 HEK-293T C369(0.97); C246(1.03); C51(1.09)  LDD1668  [9]
 LDCM0466  CL73 HEK-293T C369(1.05); C51(1.10)  LDD1669  [9]
 LDCM0467  CL74 HEK-293T C369(0.96); C246(0.92); C51(0.93)  LDD1670  [9]
 LDCM0469  CL76 HCT 116 C51(0.90); C57(0.90)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C51(1.07); C57(1.07)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C51(1.07); C57(1.07)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C51(1.07); C57(1.07)  LDD0789  [3]
 LDCM0473  CL8 HEK-293T C369(1.12); C51(1.45)  LDD1676  [9]
 LDCM0474  CL80 HCT 116 C51(0.96); C57(0.96)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C51(0.94); C57(0.94)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C51(1.09); C57(1.09)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C51(0.96); C57(0.96)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C51(1.40); C57(1.40)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C51(0.90); C57(0.90)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C51(1.05); C57(1.05)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C51(1.20); C57(1.20)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C51(1.01); C57(1.01)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C51(0.98); C57(0.98)  LDD0800  [3]
 LDCM0484  CL9 HEK-293T C369(0.92); C246(1.02); C51(1.12)  LDD1687  [9]
 LDCM0485  CL90 HCT 116 C51(1.11); C57(1.11)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C51(1.16); C57(1.16)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C51(1.19); C57(1.19)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C51(1.10); C57(1.10)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C51(0.94); C57(0.94)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C51(0.99); C57(0.99)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C51(1.04); C57(1.04)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C51(1.05); C57(1.05)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C51(0.92); C57(0.92)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C51(1.02); C57(1.02)  LDD0811  [3]
 LDCM0027  Dopamine HEK-293T 6.31  LDD0179  [2]
 LDCM0495  E2913 HEK-293T C369(1.04); C246(1.06); C51(1.02)  LDD1698  [9]
 LDCM0468  Fragment33 HEK-293T C369(0.94); C246(1.23); C51(0.93)  LDD1671  [9]
 LDCM0427  Fragment51 HEK-293T C51(0.85); C57(0.85)  LDD1025  [3]
 LDCM0022  KB02 HCT 116 C246(2.40)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C246(1.71)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C246(2.12)  LDD0082  [3]
 LDCM0030  Luteolin HEK-293T 40.78  LDD0182  [2]
 LDCM0032  Oleacein HEK-293T 9.77  LDD0184  [2]
 LDCM0029  Quercetin HEK-293T 25.00  LDD0181  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Glutathione S-transferase 3, mitochondrial (MGST3) MAPEG family O14880
GTP-binding protein SAR1a (SAR1A) SAR1 family Q9NR31
Tripartite motif-containing protein 59 (TRIM59) TRIM/RBCC family Q8IWR1
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Aquaporin-2 (AQP2) MIP/aquaporin (TC 1.A.8) family P41181
Syntaxin-1A (STX1A) Syntaxin family Q16623
Syntaxin-4 (STX4) Syntaxin family Q12846
Immunoglobulin
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Junctional adhesion molecule A (F11R) Immunoglobulin superfamily Q9Y624
Poliovirus receptor (PVR) Nectin family P15151
Leucine-rich repeat-containing protein 4C (LRRC4C) . Q9HCJ2
Other
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Apolipoprotein C-IV (APOC4) Apolipoprotein C4 family P55056
Protein FAM9B (FAM9B) FAM9 family Q8IZU0
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Kinesin light chain 3 (KLC3) Kinesin light chain family Q6P597
Vesicle-associated membrane protein 4 (VAMP4) Synaptobrevin family O75379
Vesicle-associated membrane protein 7 (VAMP7) Synaptobrevin family P51809
Syntaxin-12 (STX12) Syntaxin family Q86Y82
Syntaxin-1B (STX1B) Syntaxin family P61266
Fetal and adult testis-expressed transcript protein (FATE1) . Q969F0
Lck-interacting transmembrane adapter 1 (LIME1) . Q9H400
Melanoma-associated antigen 6 (MAGEA6) . P43360
Protein KASH5 (KASH5) . Q8N6L0
Sperm-associated antigen 5 (SPAG5) . Q96R06

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
6 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402