Details of the Probe

General Information of Probe

Probe ID
LDPC0508
Probe Name
C278
Synonyms
Z4282860719
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 335.4
Lipid-water partition coefficient (xlogp) 3.3
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C20H21N3O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-spiro[chromene-2,1'-cyclobutane]-6-ylpropanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=CC3=C(C=C2)OC4(CCC4)C=C3
InChI
InChI=1S/C20H21N3O2/c1-2-3-11-20(22-23-20)13-8-18(24)21-16-5-6-17-15(14-16)7-12-19(25-17)9-4-10-19/h1,5-7,12,14H,3-4,8-11,13H2,(H,21,24)
InChIKey
BGOASFCQUSELCT-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

105 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 62.68  LDD1948 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 72.00  LDD1948 
5-hydroxymethyl-dUMP N-hydrolase (DNPH1) LDTP00813 48.17  LDD1948 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 51.63  LDD1948 
Adenosine deaminase (ADA) LDTP01803 86.82  LDD1948 
ADP-dependent glucokinase (ADPGK) LDTP11127 88.65  LDD1948 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 62.68  LDD1948 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 99.73  LDD1948 
All trans-polyprenyl-diphosphate synthase PDSS1 (PDSS1) LDTP07104 47.50  LDD1948 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 59.71  LDD1948 
ATPase PAAT (PAAT) LDTP12057 48.50  LDD1948 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 53.82  LDD1948 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 62.68  LDD1948 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 99.73  LDD1948 
Catechol O-methyltransferase (COMT) LDTP03145 60.13  LDD1948 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 91.14  LDD1948 
Ceramide glucosyltransferase (UGCG) LDTP06617 47.84  LDD1948 
Ceramide synthase 2 (CERS2) LDTP10329 54.95  LDD1948 
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) LDTP05638 58.89  LDD1948 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 51.98  LDD1948 
CTD small phosphatase-like protein 2 (CTDSPL2) LDTP14814 51.27  LDD1948 
Cyanocobalamin reductase / alkylcobalamin dealkylase (MMACHC) LDTP14073 48.84  LDD1948 
Cysteine desulfurase (NFS1) LDTP14223 63.12  LDD1948 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1948 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 95.67  LDD1948 
Cytochrome b-c1 complex subunit Rieske, mitochondrial (UQCRFS1) LDTP04144 59.71  LDD1948 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1948 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 99.73  LDD1948 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 48.50  LDD1948 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 54.57  LDD1948 
DCN1-like protein 5 (DCUN1D5) LDTP11199 89.88  LDD1948 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 75.06  LDD1948 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 51.98  LDD1948 
DNA primase large subunit (PRIM2) LDTP04273 54.95  LDD1948 
Dolichol-phosphate mannosyltransferase subunit 1 (DPM1) LDTP01047 50.56  LDD1948 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 98.36  LDD1948 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 76.11  LDD1948 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 47.50  LDD1948 
Enoyl-[acyl-carrier-protein] reductase, mitochondrial (MECR) LDTP11271 99.73  LDD1948 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 52.71  LDD1948 
Glucose-6-phosphate isomerase (GPI) LDTP02162 73.01  LDD1948 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 50.91  LDD1948 
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (QRSL1) LDTP11728 65.80  LDD1948 
Glutaredoxin-related protein 5, mitochondrial (GLRX5) LDTP08181 76.11  LDD1948 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 85.63  LDD1948 
Glutathione-specific gamma-glutamylcyclotransferase 2 (CHAC2) LDTP15626 58.08  LDD1948 
GTP-binding protein SAR1b (SAR1B) LDTP14231 52.35  LDD1948 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 99.73  LDD1948 
Heme A synthase COX15 (COX15) LDTP07931 64.89  LDD1948 
Heme oxygenase 1 (HMOX1) LDTP02359 91.14  LDD1948 
Histone-arginine methyltransferase CARM1 (CARM1) LDTP08352 61.39  LDD1948 
Holocytochrome c-type synthase (HCCS) LDTP04581 64.89  LDD1948 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 49.18  LDD1948 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 99.73  LDD1948 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 86.22  LDD1948 
Large ribosomal subunit protein mL62 (MRPL58) LDTP06080 99.73  LDD1948 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 72.00  LDD1948 
Methionine aminopeptidase 1 (METAP1) LDTP04565 48.50  LDD1948 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 52.71  LDD1948 
Mitochondrial genome maintenance exonuclease 1 (MGME1) LDTP11090 56.10  LDD1948 
Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) LDTP06810 55.72  LDD1948 
Mitochondrial mRNA pseudouridine synthase RPUSD3 (RPUSD3) LDTP07499 48.50  LDD1948 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 67.65  LDD1948 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 99.73  LDD1948 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 61.82  LDD1948 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 51.63  LDD1948 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 97.01  LDD1948 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 61.39  LDD1948 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 63.56  LDD1948 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 49.52  LDD1948 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 48.84  LDD1948 
NIF3-like protein 1 (NIF3L1) LDTP11648 57.68  LDD1948 
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EARS2) LDTP06997 77.17  LDD1948 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 62.25  LDD1948 
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C) LDTP09355 53.82  LDD1948 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 66.26  LDD1948 
Pirin (PIR) LDTP00325 99.73  LDD1948 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 81.57  LDD1948 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 96.34  LDD1948 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 51.27  LDD1948 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 55.72  LDD1948 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 86.22  LDD1948 
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) LDTP04925 61.39  LDD1948 
RAC-alpha serine/threonine-protein kinase (AKT1) LDTP03607 53.82  LDD1948 
Replication factor C subunit 5 (RFC5) LDTP03910 68.12  LDD1948 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 56.49  LDD1948 
Sepiapterin reductase (SPR) LDTP03730 49.52  LDD1948 
Septin-7 (SEPTIN7) LDTP06513 66.72  LDD1948 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 54.57  LDD1948 
Serine protease HTRA2, mitochondrial (HTRA2) LDTP00773 50.56  LDD1948 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 95.67  LDD1948 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 74.03  LDD1948 
Signal recognition particle subunit SRP54 (SRP54) LDTP04890 52.71  LDD1948 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 53.45  LDD1948 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 50.21  LDD1948 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 57.68  LDD1948 
Torsin-1B (TOR1B) LDTP00400 72.50  LDD1948 
Translation factor GUF1, mitochondrial (GUF1) LDTP15416 49.87  LDD1948 
tRNA (guanine-N(7)-)-methyltransferase (METTL1) LDTP13140 65.80  LDD1948 
Tryptophan--tRNA ligase, mitochondrial (WARS2) LDTP13238 81.57  LDD1948 
Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) LDTP04874 48.17  LDD1948 
Uridine-cytidine kinase 2 (UCK2) LDTP11571 65.80  LDD1948 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 50.21  LDD1948 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 48.50  LDD1948 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (PDK3) LDTP06322 74.03  LDD1948 
------------------------------------------------------------------------------------
⏷ Show the Full List of 105 Enzyme
80 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 56.49  LDD1948 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 49.87  LDD1948 
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 53.82  LDD1948 
Adaptin ear-binding coat-associated protein 2 (NECAP2) LDTP16115 57.28  LDD1948 
Annexin A1 (ANXA1) LDTP02010 55.33  LDD1948 
Apoptosis regulator BAX (BAX) LDTP05528 48.17  LDD1948 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 99.73  LDD1948 
ATP synthase F(0) complex subunit C2, mitochondrial (ATP5MC2) LDTP05474 56.49  LDD1948 
ATP synthase subunit d, mitochondrial (ATP5PD) LDTP14509 48.50  LDD1948 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 99.73  LDD1948 
BRI3-binding protein (BRI3BP) LDTP15648 99.73  LDD1948 
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB) LDTP12725 67.18  LDD1948 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 89.26  LDD1948 
Coiled-coil domain-containing protein 22 (CCDC22) LDTP01056 50.91  LDD1948 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 93.70  LDD1948 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 81.57  LDD1948 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 54.95  LDD1948 
Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) LDTP03064 99.73  LDD1948 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1948 
Cytochrome c oxidase subunit 7C, mitochondrial (COX7C) LDTP02818 56.10  LDD1948 
Derlin-1 (DERL1) LDTP11245 66.26  LDD1948 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 70.03  LDD1948 
ER membrane protein complex subunit 2 (EMC2) LDTP06271 53.45  LDD1948 
ER membrane protein complex subunit 3 (EMC3) LDTP12958 53.45  LDD1948 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.73  LDD1948 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 79.34  LDD1948 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 92.41  LDD1948 
Importin-4 (IPO4) LDTP09515 47.50  LDD1948 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 64.00  LDD1948 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 58.08  LDD1948 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 74.03  LDD1948 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 99.73  LDD1948 
Metaxin-1 (MTX1) LDTP05900 99.73  LDD1948 
MICOS complex subunit MIC26 (APOO) LDTP11250 73.01  LDD1948 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 51.63  LDD1948 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 61.39  LDD1948 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 58.49  LDD1948 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 99.73  LDD1948 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 99.73  LDD1948 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 99.73  LDD1948 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1948 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1948 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 50.91  LDD1948 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 99.73  LDD1948 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 61.82  LDD1948 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 49.18  LDD1948 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 89.26  LDD1948 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 55.33  LDD1948 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 56.10  LDD1948 
PRA1 family protein 2 (PRAF2) LDTP01060 53.82  LDD1948 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 49.87  LDD1948 
Programmed cell death protein 6 (PDCD6) LDTP01180 56.49  LDD1948 
Protein GPR108 (GPR108) LDTP12383 97.01  LDD1948 
Protein tweety homolog 3 (TTYH3) LDTP11615 48.50  LDD1948 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 87.43  LDD1948 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 51.63  LDD1948 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 92.41  LDD1948 
Sideroflexin-4 (SFXN4) LDTP07531 77.17  LDD1948 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 60.97  LDD1948 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 47.84  LDD1948 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 99.73  LDD1948 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 51.27  LDD1948 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 63.12  LDD1948 
Syntaxin-5 (STX5) LDTP05780 80.45  LDD1948 
Tetraspanin-3 (TSPAN3) LDTP16813 74.54  LDD1948 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 54.19  LDD1948 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1948 
Transmembrane protein 126A (TMEM126A) LDTP15948 99.73  LDD1948 
Transmembrane protein 14C (TMEM14C) LDTP12979 49.87  LDD1948 
Transmembrane protein 160 (TMEM160) LDTP20002 99.73  LDD1948 
Transmembrane protein 205 (TMEM205) LDTP07667 63.56  LDD1948 
Transmembrane protein 230 (TMEM230) LDTP10065 90.51  LDD1948 
Transmembrane protein 87A (TMEM87A) LDTP15481 58.49  LDD1948 
Vacuole membrane protein 1 (VMP1) LDTP10343 84.45  LDD1948 
Vezatin (VEZT) LDTP12191 97.01  LDD1948 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 76.64  LDD1948 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 79.34  LDD1948 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 71.51  LDD1948 
WASH complex subunit 3 (WASHC3) LDTP13973 48.50  LDD1948 
Zinc transporter 7 (SLC30A7) LDTP09180 67.65  LDD1948 
------------------------------------------------------------------------------------
⏷ Show the Full List of 80 Transporter and channel
4 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 87.43  LDD1948 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 48.50  LDD1948 
High mobility group protein B2 (HMGB2) LDTP03363 48.50  LDD1948 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 51.63  LDD1948 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Cell adhesion molecule 1 (CADM1) LDTP11441 51.63  LDD1948 
------------------------------------------------------------------------------------
92 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein beta/alpha (YWHAB) LDTP03617 65.34  LDD1948 
14-3-3 protein eta (YWHAH) LDTP05442 51.63  LDD1948 
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 50.21  LDD1948 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 81.57  LDD1948 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1948 
BET1 homolog (BET1) LDTP00555 51.98  LDD1948 
BRISC and BRCA1-A complex member 2 (BABAM2) LDTP12788 48.17  LDD1948 
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (KCTD10) LDTP11864 58.49  LDD1948 
Calpain small subunit 1 (CAPNS1) LDTP02047 51.27  LDD1948 
Calponin-2 (CNN2) LDTP10864 49.18  LDD1948 
Charged multivesicular body protein 3 (CHMP3) LDTP13990 57.28  LDD1948 
Cobalamin trafficking protein CblD (MMADHC) LDTP11871 58.49  LDD1948 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 71.51  LDD1948 
COP9 signalosome complex subunit 7a (COPS7A) LDTP13170 61.39  LDD1948 
Cytochrome c oxidase assembly protein COX14 (COX14) LDTP15741 77.71  LDD1948 
DnaJ homolog subfamily C member 9 (DNAJC9) LDTP09721 72.00  LDD1948 
ELMO domain-containing protein 2 (ELMOD2) LDTP17659 93.05  LDD1948 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 47.50  LDD1948 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 55.72  LDD1948 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 85.63  LDD1948 
Ganglioside GM2 activator (GM2A) LDTP02927 77.17  LDD1948 
GH3 domain-containing protein (GHDC) LDTP08795 63.12  LDD1948 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 61.82  LDD1948 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 81.01  LDD1948 
HEAT repeat-containing protein 6 (HEATR6) LDTP17313 99.73  LDD1948 
IST1 homolog (IST1) LDTP04593 51.98  LDD1948 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 88.65  LDD1948 
Kinesin light chain 4 (KLC4) LDTP12591 79.89  LDD1948 
Kinetochore protein Spc24 (SPC24) LDTP09069 53.82  LDD1948 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 48.84  LDD1948 
Large ribosomal subunit protein bL28m (MRPL28) LDTP05741 73.52  LDD1948 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 48.50  LDD1948 
Large ribosomal subunit protein uL11m (MRPL11) LDTP13971 64.45  LDD1948 
Lipase maturation factor 2 (LMF2) LDTP15887 74.54  LDD1948 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 61.39  LDD1948 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 99.73  LDD1948 
Mitochondrial calcium uniporter regulator 1 (MCUR1) LDTP10093 62.25  LDD1948 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 99.73  LDD1948 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1948 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1948 
Myosin light chain 6B (MYL6B) LDTP02736 93.70  LDD1948 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 64.89  LDD1948 
Nucleobindin-2 (NUCB2) LDTP05160 68.59  LDD1948 
Nucleolar protein 9 (NOP9) LDTP15283 99.73  LDD1948 
Nurim (NRM) LDTP08606 81.57  LDD1948 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 75.58  LDD1948 
Optic atrophy 3 protein (OPA3) LDTP16006 69.55  LDD1948 
Paraneoplastic antigen Ma1 (PNMA1) LDTP09119 68.12  LDD1948 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 54.95  LDD1948 
Prefoldin subunit 5 (PFDN5) LDTP10873 50.21  LDD1948 
Prohibitin-2 (PHB2) LDTP10924 49.52  LDD1948 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 76.64  LDD1948 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 49.87  LDD1948 
Protein CEBPZOS (CEBPZOS) LDTP18883 99.73  LDD1948 
Protein FAM114A2 (FAM114A2) LDTP16080 94.35  LDD1948 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD1948 
Protein FAM3C (FAM3C) LDTP09773 56.49  LDD1948 
Protein jagunal homolog 1 (JAGN1) LDTP08904 63.56  LDD1948 
Protein MTO1 homolog, mitochondrial (MTO1) LDTP13936 52.35  LDD1948 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 81.57  LDD1948 
Protein PAXX (PAXX) LDTP11235 65.34  LDD1948 
Protein transport protein Sec16A (SEC16A) LDTP00512 47.84  LDD1948 
Protein unc-119 homolog B (UNC119B) LDTP00105 66.26  LDD1948 
Protein YIF1A (YIF1A) LDTP01494 65.80  LDD1948 
Protein YIPF4 (YIPF4) LDTP11167 47.50  LDD1948 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 67.65  LDD1948 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 47.84  LDD1948 
Reticulon-2 (RTN2) LDTP01167 87.43  LDD1948 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1948 
Reticulophagy regulator 2 (RETREG2) LDTP09080 51.98  LDD1948 
Shootin-1 (SHTN1) LDTP00019 48.50  LDD1948 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 56.10  LDD1948 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 67.65  LDD1948 
Small integral membrane protein 12 (SMIM12) LDTP19859 54.57  LDD1948 
Small ribosomal subunit protein mS23 (MRPS23) LDTP13985 99.73  LDD1948 
Small ribosomal subunit protein mS31 (MRPS31) LDTP09836 47.50  LDD1948 
Small ribosomal subunit protein mS35 (MRPS35) LDTP14788 48.50  LDD1948 
Sorcin (SRI) LDTP03554 51.98  LDD1948 
Synaptosomal-associated protein 47 (SNAP47) LDTP07061 55.72  LDD1948 
Syntaxin-18 (STX18) LDTP13086 87.43  LDD1948 
Syntaxin-7 (STX7) LDTP00632 61.82  LDD1948 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 94.35  LDD1948 
TraB domain-containing protein (TRABD) LDTP19963 87.43  LDD1948 
Transcription elongation factor, mitochondrial (TEFM) LDTP10735 71.01  LDD1948 
Transcription termination factor 2, mitochondrial (MTERF2) LDTP06831 69.07  LDD1948 
Transmembrane protein 209 (TMEM209) LDTP18272 50.56  LDD1948 
Trophoblast glycoprotein (TPBG) LDTP05960 78.79  LDD1948 
Tubulin epsilon and delta complex protein 1 (TEDC1) LDTP15278 48.84  LDD1948 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 99.73  LDD1948 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 64.45  LDD1948 
Uncharacterized protein C1orf122 (C1orf122) LDTP19568 76.11  LDD1948 
Vacuolar protein-sorting-associated protein 25 (VPS25) LDTP11108 72.50  LDD1948 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1948 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587