Details of the Target

General Information of Target

Target ID LDTP17313
Target Name HEAT repeat-containing protein 6 (HEATR6)
Gene Name HEATR6
Gene ID 63897
Synonyms
ABC1; HEAT repeat-containing protein 6; Amplified in breast cancer protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSEQKQLFCDEKQTTLKKDYDVKNEIVDRSAPKPKISGSIHYALKNVKIDLPKINIPNE
VLLKHEVDKYRKLFQSKQQTARKSISIKTVSCVEECTLLHKSERAEEEGVKMSAKILNFS
CLKCRDNTRYSPNDLQKHFQMWHHGELPSYPCEMCNFSANDFQVFKQHRRTHRSTLVKCD
ICNNESVYTLLNLTKHFTSTHCVNGNFQCEKCKFSTQDVGTFVQHIHRHNEIHYKCGKCH
HVCFTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKY
EKRMAKTSAGLKLILKRYKIGASRKTFWKRKKINSGSDRSIEKNTQVLKKMNKTQTKSED
QSHVVQEHLSEEKDERLHCENNDKAPESESEKPTPLSTGQGNRAEEGPNASSGFMKTAVL
GPTLKNVMMKNNKLAVSPNYNATFMGFKMMDGKQHIVLKLVPIKQNVCSPGSQSGAAKDG
TANLQPQTLDTNGFLTGVTTELNDTVYMKAATPFSCSSSILSGKASSEKEMTLISQRNNM
LQTMDYEKSVSSLSATSELVTASVNLTTKFETRDNVDFWGNHLTQSHPEVLGTTIKSPDK
VNCVAKPNAYNSGDMHNYCINYGNCELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTAVY
ENPQRESSSSKTVVQQPISESFLSLVRQESSKPDSLLASISLLNDKDGTLKAKSEIEEQY
VLEKGQNIDGQNLYSNENQNLECATEKSKWEDFSNVDSPMMPRITSVFSLQSQQASEFLP
PEVNQLLQDVLKIKPDVKQDSSNTPNKGLPLHCDQSFQKHEREGKIVESSKDFKVQGIFP
VPPGSVGINVPTNDLNLKFGKEKQVSSIPQDVRDSEKMPRISGFGTLLKTQSDAIITQQL
VKDKLRATTQNLGSFYMQSPLLNSEQKKTIIVQTSKGFLIPLNITNKPGLPVIPGNALPL
VNSQGIPASLFVNKKPGMVLTLNNGKLEGVSAVKTEGAPARGTVTKEPCKTPILKVEPNN
NCLTPGLCSSIGSCLSMKSSSENTLPLKGPYILKPTSSVKAVLIPNMLSEQQSTKLNISD
SVKQQNEIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYQNIQPKKPEGTP
QRILLKIFNPVLNVTAANNLSVSNSASSLQKDNVPSNQIIGGEQKEPESRDALPFLLDDL
MPANEIVITSTATCPESSEEPICVSDCSESRVLRCKTNCRIERNFNRKKTSKKIFSKTKT
HGSKDSETAFVSRNRNCKRKCRDSYQEPPRRKATLHRKCKEKAKPEDVRETFGFSRPRLS
KDSIRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVSVMKTIAKFNGHVLKVSLS
KRTINALLKPVCYNPPKTTYDDFSKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTT
SENILKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE
Target Bioclass
Other
Function Amplification-dependent oncogene.
Uniprot ID
Q6AI08
Ensemble ID
ENST00000184956.11
HGNC ID
HGNC:24076

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		14.45  LDD0402  [1]
Probe 1
 Probe Info  		Y1033(32.06); Y1039(41.99)  LDD3495  [2]
DBIA
 Probe Info  		C846(19.63); C651(5.91); C1065(5.10)  LDD0209  [3]
4-Iodoacetamidophenylacetylene
 Probe Info  		C977(0.00); C476(0.00)  LDD0038  [4]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [4]
Lodoacetamide azide
 Probe Info  		C476(0.00); C720(0.00); C977(0.00)  LDD0037  [4]
NAIA_4
 Probe Info  		C360(0.00); C476(0.00); C846(0.00)  LDD2226  [5]
IPM
 Probe Info  		N.A.  LDD0005  [6]
TFBX
 Probe Info  		N.A.  LDD0148  [7]
AOyne
 Probe Info  		12.00  LDD0443  [8]
NAIA_5
 Probe Info  		C476(0.00); C514(0.00); C846(0.00); C793(0.00)  LDD2223  [5]
PAL-AfBPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C278
 Probe Info  		99.73  LDD1948  [9]
C282
 Probe Info  		22.78  LDD1952  [9]
C284
 Probe Info  		31.56  LDD1954  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C476(11.66)  LDD0371  [10]
 LDCM0026  4SU-RNA+native RNA HEK-293T C476(5.10)  LDD0372  [10]
 LDCM0214  AC1 HCT 116 C360(0.98); C38(0.84); C426(1.19); C514(1.04)  LDD0531  [11]
 LDCM0215  AC10 HCT 116 C360(1.05); C426(1.13); C651(0.90); C669(1.18)  LDD0532  [11]
 LDCM0216  AC100 HCT 116 C360(0.92); C38(1.31); C426(0.79); C651(1.03)  LDD0533  [11]
 LDCM0217  AC101 HCT 116 C360(1.07); C38(1.25); C426(0.84); C651(0.94)  LDD0534  [11]
 LDCM0218  AC102 HCT 116 C360(0.97); C38(1.24); C426(0.78); C651(0.86)  LDD0535  [11]
 LDCM0219  AC103 HCT 116 C360(1.09); C38(1.33); C426(0.92); C651(0.93)  LDD0536  [11]
 LDCM0220  AC104 HCT 116 C360(1.10); C38(1.17); C426(0.94); C651(0.90)  LDD0537  [11]
 LDCM0221  AC105 HCT 116 C360(1.13); C38(1.36); C426(0.90); C651(1.06)  LDD0538  [11]
 LDCM0222  AC106 HCT 116 C360(1.26); C38(1.47); C426(0.86); C651(0.96)  LDD0539  [11]
 LDCM0223  AC107 HCT 116 C360(1.20); C38(1.22); C426(0.71); C651(1.18)  LDD0540  [11]
 LDCM0224  AC108 HCT 116 C360(0.91); C38(1.28); C426(0.60); C651(1.11)  LDD0541  [11]
 LDCM0225  AC109 HCT 116 C360(1.00); C38(0.99); C426(0.63); C651(0.95)  LDD0542  [11]
 LDCM0226  AC11 HCT 116 C360(1.31); C426(1.16); C651(0.83); C669(0.89)  LDD0543  [11]
 LDCM0227  AC110 HCT 116 C360(0.91); C38(1.34); C426(0.59); C651(0.87)  LDD0544  [11]
 LDCM0228  AC111 HCT 116 C360(0.93); C38(1.35); C426(0.61); C651(0.97)  LDD0545  [11]
 LDCM0229  AC112 HCT 116 C360(1.22); C38(1.45); C426(0.59); C651(1.23)  LDD0546  [11]
 LDCM0230  AC113 HCT 116 C360(0.98); C38(0.86); C426(1.05); C651(1.01)  LDD0547  [11]
 LDCM0231  AC114 HCT 116 C360(1.09); C38(1.21); C426(1.22); C651(1.09)  LDD0548  [11]
 LDCM0232  AC115 HCT 116 C360(1.20); C38(0.99); C426(1.39); C651(1.19)  LDD0549  [11]
 LDCM0233  AC116 HCT 116 C360(1.22); C38(1.13); C426(1.30); C651(1.29)  LDD0550  [11]
 LDCM0234  AC117 HCT 116 C360(1.12); C38(0.98); C426(1.22); C651(1.18)  LDD0551  [11]
 LDCM0235  AC118 HCT 116 C360(0.98); C38(1.07); C426(1.07); C651(1.25)  LDD0552  [11]
 LDCM0236  AC119 HCT 116 C360(1.02); C38(1.08); C426(1.13); C651(1.22)  LDD0553  [11]
 LDCM0237  AC12 HCT 116 C360(1.20); C426(0.99); C651(0.76); C669(0.74)  LDD0554  [11]
 LDCM0238  AC120 HCT 116 C360(1.09); C38(1.11); C426(1.31); C651(1.16)  LDD0555  [11]
 LDCM0239  AC121 HCT 116 C360(0.97); C38(0.91); C426(1.00); C651(1.36)  LDD0556  [11]
 LDCM0240  AC122 HCT 116 C360(1.16); C38(1.23); C426(0.86); C651(1.07)  LDD0557  [11]
 LDCM0241  AC123 HCT 116 C360(0.92); C38(0.96); C426(0.91); C651(1.11)  LDD0558  [11]
 LDCM0242  AC124 HCT 116 C360(1.04); C38(1.15); C426(1.00); C651(1.26)  LDD0559  [11]
 LDCM0243  AC125 HCT 116 C360(1.00); C38(1.20); C426(1.07); C651(1.10)  LDD0560  [11]
 LDCM0244  AC126 HCT 116 C360(1.19); C38(1.13); C426(1.18); C651(1.17)  LDD0561  [11]
 LDCM0245  AC127 HCT 116 C360(1.21); C38(0.98); C426(1.13); C651(1.07)  LDD0562  [11]
 LDCM0246  AC128 HCT 116 C360(0.57); C651(1.26); C846(1.02); C977(1.09)  LDD0563  [11]
 LDCM0247  AC129 HCT 116 C360(0.63); C651(1.18); C846(0.89); C977(1.10)  LDD0564  [11]
 LDCM0249  AC130 HCT 116 C360(0.53); C651(1.15); C846(0.94); C977(1.00)  LDD0566  [11]
 LDCM0250  AC131 HCT 116 C360(0.80); C651(0.96); C846(1.28); C977(1.10)  LDD0567  [11]
 LDCM0251  AC132 HCT 116 C360(0.73); C651(1.32); C846(0.82); C977(0.97)  LDD0568  [11]
 LDCM0252  AC133 HCT 116 C360(0.57); C651(1.36); C846(0.85); C977(0.98)  LDD0569  [11]
 LDCM0253  AC134 HCT 116 C360(0.73); C651(1.19); C846(0.89); C977(1.06)  LDD0570  [11]
 LDCM0254  AC135 HCT 116 C360(0.75); C651(1.38); C846(1.01); C977(0.99)  LDD0571  [11]
 LDCM0255  AC136 HCT 116 C360(0.70); C651(1.07); C846(0.89); C977(1.03)  LDD0572  [11]
 LDCM0256  AC137 HCT 116 C360(0.71); C651(1.17); C846(0.94); C977(1.06)  LDD0573  [11]
 LDCM0257  AC138 HCT 116 C360(1.28); C651(1.45); C846(0.78); C977(1.11)  LDD0574  [11]
 LDCM0258  AC139 HCT 116 C360(1.20); C651(1.26); C846(0.95); C977(1.04)  LDD0575  [11]
 LDCM0259  AC14 HCT 116 C360(1.08); C426(1.09); C651(0.78); C669(0.93)  LDD0576  [11]
 LDCM0260  AC140 HCT 116 C360(0.90); C651(1.33); C846(0.95); C977(1.08)  LDD0577  [11]
 LDCM0261  AC141 HCT 116 C360(0.92); C651(1.44); C846(0.87); C977(1.07)  LDD0578  [11]
 LDCM0262  AC142 HCT 116 C360(0.96); C651(1.05); C846(0.78); C977(0.92)  LDD0579  [11]
 LDCM0263  AC143 HCT 116 C360(1.20); C38(1.25); C426(0.97); C651(0.90)  LDD0580  [11]
 LDCM0264  AC144 HCT 116 C977(0.92); C38(0.93); C846(1.03); C651(1.05)  LDD0581  [11]
 LDCM0265  AC145 HCT 116 C651(0.97); C977(0.98); C846(0.99); C38(1.02)  LDD0582  [11]
 LDCM0266  AC146 HCT 116 C977(0.89); C651(0.89); C846(1.01); C426(1.13)  LDD0583  [11]
 LDCM0267  AC147 HCT 116 C977(0.94); C651(0.99); C38(1.09); C846(1.10)  LDD0584  [11]
 LDCM0268  AC148 HCT 116 C651(0.84); C977(1.13); C38(1.19); C846(1.36)  LDD0585  [11]
 LDCM0269  AC149 HCT 116 C977(0.92); C651(0.92); C846(1.04); C38(1.11)  LDD0586  [11]
 LDCM0270  AC15 HCT 116 C651(0.89); C977(0.90); C846(0.92); C360(1.16)  LDD0587  [11]
 LDCM0271  AC150 HCT 116 C846(0.97); C651(0.99); C977(1.00); C38(1.04)  LDD0588  [11]
 LDCM0272  AC151 HCT 116 C977(0.94); C38(1.02); C426(1.04); C846(1.05)  LDD0589  [11]
 LDCM0273  AC152 HCT 116 C651(0.94); C38(0.95); C846(1.05); C977(1.06)  LDD0590  [11]
 LDCM0274  AC153 HCT 116 C651(1.03); C38(1.21); C977(1.23); C846(1.52)  LDD0591  [11]
 LDCM0621  AC154 HCT 116 C360(1.34); C38(1.09); C426(1.32); C651(1.00)  LDD2158  [11]
 LDCM0622  AC155 HCT 116 C360(1.23); C38(1.07); C426(1.19); C651(1.00)  LDD2159  [11]
 LDCM0623  AC156 HCT 116 C360(1.05); C38(0.91); C426(0.92); C651(0.89)  LDD2160  [11]
 LDCM0624  AC157 HCT 116 C360(1.13); C38(1.07); C426(1.03); C651(0.93)  LDD2161  [11]
 LDCM0276  AC17 HCT 116 C977(0.82); C651(1.01); C426(1.12); C514(1.12)  LDD0593  [11]
 LDCM0277  AC18 HCT 116 C720(0.91); C977(1.00); C846(1.16); C651(1.21)  LDD0594  [11]
 LDCM0278  AC19 HCT 116 C977(0.91); C846(1.02); C651(1.06); C360(1.07)  LDD0595  [11]
 LDCM0279  AC2 HCT 116 C514(0.78); C846(0.85); C977(0.87); C38(0.87)  LDD0596  [11]
 LDCM0280  AC20 HCT 116 C720(0.80); C977(0.95); C651(1.03); C514(1.06)  LDD0597  [11]
 LDCM0281  AC21 HCT 116 C977(0.88); C846(0.98); C720(1.02); C651(1.03)  LDD0598  [11]
 LDCM0282  AC22 HCT 116 C977(0.84); C720(0.87); C651(0.90); C514(0.94)  LDD0599  [11]
 LDCM0283  AC23 HCT 116 C977(0.81); C720(0.87); C651(0.89); C514(0.92)  LDD0600  [11]
 LDCM0284  AC24 HCT 116 C977(0.83); C720(0.91); C651(0.99); C426(1.06)  LDD0601  [11]
 LDCM0285  AC25 HCT 116 C38(0.90); C977(0.94); C720(0.95); C846(1.00)  LDD0602  [11]
 LDCM0286  AC26 HCT 116 C720(0.81); C846(0.90); C38(1.02); C669(1.05)  LDD0603  [11]
 LDCM0287  AC27 HCT 116 C720(0.94); C38(0.96); C846(0.96); C977(1.06)  LDD0604  [11]
 LDCM0288  AC28 HCT 116 C720(0.87); C38(0.95); C846(0.98); C651(1.14)  LDD0605  [11]
 LDCM0289  AC29 HCT 116 C720(0.73); C38(0.86); C846(0.99); C651(1.14)  LDD0606  [11]
 LDCM0290  AC3 HCT 116 C846(0.82); C360(0.83); C977(0.85); C38(1.01)  LDD0607  [11]
 LDCM0291  AC30 HCT 116 C720(0.79); C38(0.87); C846(0.95); C977(1.27)  LDD0608  [11]
 LDCM0292  AC31 HCT 116 C846(0.91); C38(0.93); C977(1.03); C720(1.03)  LDD0609  [11]
 LDCM0293  AC32 HCT 116 C38(0.85); C846(0.96); C720(1.15); C977(1.15)  LDD0610  [11]
 LDCM0294  AC33 HCT 116 C38(0.82); C720(0.83); C846(0.95); C977(0.98)  LDD0611  [11]
 LDCM0295  AC34 HCT 116 C720(0.77); C38(0.91); C977(1.12); C846(1.14)  LDD0612  [11]
 LDCM0296  AC35 HCT 116 C360(0.88); C426(0.92); C720(0.92); C669(0.95)  LDD0613  [11]
 LDCM0297  AC36 HCT 116 C360(0.74); C669(0.84); C846(0.86); C651(0.89)  LDD0614  [11]
 LDCM0298  AC37 HCT 116 C360(0.78); C651(0.79); C38(0.88); C720(0.88)  LDD0615  [11]
 LDCM0299  AC38 HCT 116 C360(0.82); C651(0.90); C846(0.94); C977(1.00)  LDD0616  [11]
 LDCM0300  AC39 HCT 116 C426(0.93); C360(0.93); C846(0.93); C720(0.93)  LDD0617  [11]
 LDCM0301  AC4 HCT 116 C846(0.87); C360(0.88); C38(0.89); C977(0.89)  LDD0618  [11]
 LDCM0302  AC40 HCT 116 C651(0.77); C360(0.84); C720(1.01); C846(1.10)  LDD0619  [11]
 LDCM0303  AC41 HCT 116 C360(0.76); C720(0.83); C846(0.87); C426(0.92)  LDD0620  [11]
 LDCM0304  AC42 HCT 116 C651(0.89); C720(0.92); C846(0.96); C977(1.01)  LDD0621  [11]
 LDCM0305  AC43 HCT 116 C720(0.87); C977(0.97); C846(0.98); C426(1.01)  LDD0622  [11]
 LDCM0306  AC44 HCT 116 C651(0.80); C720(0.90); C846(0.95); C977(0.96)  LDD0623  [11]
 LDCM0307  AC45 HCT 116 C720(0.87); C651(0.95); C846(1.01); C977(1.08)  LDD0624  [11]
 LDCM0308  AC46 HCT 116 C669(0.78); C38(0.87); C426(0.88); C846(0.97)  LDD0625  [11]
 LDCM0309  AC47 HCT 116 C426(0.86); C38(0.89); C360(0.90); C846(0.97)  LDD0626  [11]
 LDCM0310  AC48 HCT 116 C426(0.65); C669(0.79); C38(0.80); C846(0.98)  LDD0627  [11]
 LDCM0311  AC49 HCT 116 C38(0.90); C669(0.99); C360(1.02); C977(1.29)  LDD0628  [11]
 LDCM0312  AC5 HCT 116 C360(0.82); C846(0.84); C977(0.87); C514(0.94)  LDD0629  [11]
 LDCM0313  AC50 HCT 116 C38(0.85); C360(0.94); C846(1.19); C651(1.20)  LDD0630  [11]
 LDCM0314  AC51 HCT 116 C426(0.67); C38(0.75); C360(0.95); C846(0.98)  LDD0631  [11]
 LDCM0315  AC52 HCT 116 C38(0.92); C426(0.94); C846(0.94); C360(0.99)  LDD0632  [11]
 LDCM0316  AC53 HCT 116 C38(0.73); C360(0.97); C669(1.05); C977(1.09)  LDD0633  [11]
 LDCM0317  AC54 HCT 116 C669(0.65); C38(0.76); C360(0.97); C846(1.03)  LDD0634  [11]
 LDCM0318  AC55 HCT 116 C360(0.95); C38(1.17); C846(1.22); C651(1.28)  LDD0635  [11]
 LDCM0319  AC56 HCT 116 C38(0.92); C360(1.07); C669(1.21); C651(1.40)  LDD0636  [11]
 LDCM0320  AC57 HCT 116 C977(0.87); C846(0.91); C651(1.03); C38(1.23)  LDD0637  [11]
 LDCM0321  AC58 HCT 116 C977(1.09); C651(1.09); C846(1.09); C38(1.40)  LDD0638  [11]
 LDCM0322  AC59 HCT 116 C977(0.89); C846(1.05); C651(1.18); C38(1.62)  LDD0639  [11]
 LDCM0323  AC6 HCT 116 C977(0.98); C651(1.10); C669(1.21); C360(1.26)  LDD0640  [11]
 LDCM0324  AC60 HCT 116 C977(0.80); C846(0.96); C651(1.08); C38(1.19)  LDD0641  [11]
 LDCM0325  AC61 HCT 116 C977(0.81); C846(0.85); C651(1.14); C38(1.32)  LDD0642  [11]
 LDCM0326  AC62 HCT 116 C977(0.97); C651(1.07); C846(1.08); C38(1.29)  LDD0643  [11]
 LDCM0327  AC63 HCT 116 C977(0.87); C846(0.89); C651(1.08); C38(1.27)  LDD0644  [11]
 LDCM0328  AC64 HCT 116 C977(0.89); C846(1.09); C651(1.15); C38(1.38)  LDD0645  [11]
 LDCM0329  AC65 HCT 116 C977(0.90); C846(1.01); C651(1.29); C38(1.60)  LDD0646  [11]
 LDCM0330  AC66 HCT 116 C977(0.90); C846(0.97); C651(1.34); C38(1.67)  LDD0647  [11]
 LDCM0331  AC67 HCT 116 C977(0.90); C846(0.92); C38(1.26); C651(1.36)  LDD0648  [11]
 LDCM0332  AC68 HCT 116 C38(0.67); C846(0.93); C977(0.97); C360(1.01)  LDD0649  [11]
 LDCM0333  AC69 HCT 116 C38(0.81); C360(0.99); C977(1.01); C846(1.06)  LDD0650  [11]
 LDCM0334  AC7 HCT 116 C669(0.79); C651(0.88); C977(0.96); C846(0.97)  LDD0651  [11]
 LDCM0335  AC70 HCT 116 C846(0.96); C977(1.01); C38(1.05); C360(1.18)  LDD0652  [11]
 LDCM0336  AC71 HCT 116 C38(0.85); C360(0.94); C426(0.99); C977(1.05)  LDD0653  [11]
 LDCM0337  AC72 HCT 116 C38(0.98); C977(1.02); C846(1.07); C426(1.13)  LDD0654  [11]
 LDCM0338  AC73 HCT 116 C38(0.98); C977(1.20); C360(1.38); C846(1.45)  LDD0655  [11]
 LDCM0339  AC74 HCT 116 C38(0.90); C360(1.20); C977(1.23); C651(1.35)  LDD0656  [11]
 LDCM0340  AC75 HCT 116 C38(0.83); C977(1.32); C360(1.41); C846(1.56)  LDD0657  [11]
 LDCM0341  AC76 HCT 116 C38(0.85); C977(1.03); C360(1.09); C846(1.11)  LDD0658  [11]
 LDCM0342  AC77 HCT 116 C38(0.72); C977(1.03); C846(1.04); C651(1.10)  LDD0659  [11]
 LDCM0343  AC78 HCT 116 C426(0.83); C38(0.93); C846(0.99); C977(1.00)  LDD0660  [11]
 LDCM0344  AC79 HCT 116 C38(0.83); C977(1.00); C426(1.01); C651(1.03)  LDD0661  [11]
 LDCM0345  AC8 HCT 116 C669(0.97); C651(1.01); C977(1.02); C846(1.12)  LDD0662  [11]
 LDCM0346  AC80 HCT 116 C38(0.91); C977(1.00); C360(1.06); C846(1.08)  LDD0663  [11]
 LDCM0347  AC81 HCT 116 C426(0.75); C38(0.81); C651(0.95); C846(0.99)  LDD0664  [11]
 LDCM0348  AC82 HCT 116 C38(0.74); C977(1.38); C360(1.46); C846(1.60)  LDD0665  [11]
 LDCM0349  AC83 HCT 116 C38(0.96); C977(1.11); C846(1.36); C651(1.52)  LDD0666  [11]
 LDCM0350  AC84 HCT 116 C977(1.10); C651(1.25); C846(1.29); C38(1.30)  LDD0667  [11]
 LDCM0351  AC85 HCT 116 C977(1.01); C846(1.14); C360(1.24); C426(1.29)  LDD0668  [11]
 LDCM0352  AC86 HCT 116 C977(0.97); C38(1.13); C360(1.17); C846(1.28)  LDD0669  [11]
 LDCM0353  AC87 HCT 116 C977(0.95); C38(0.96); C426(0.98); C846(1.01)  LDD0670  [11]
 LDCM0354  AC88 HCT 116 C977(0.94); C38(1.04); C651(1.15); C426(1.20)  LDD0671  [11]
 LDCM0355  AC89 HCT 116 C977(0.95); C38(1.19); C360(1.23); C651(1.29)  LDD0672  [11]
 LDCM0357  AC90 HCT 116 C360(0.79); C38(1.00); C426(1.00); C651(1.12)  LDD0674  [11]
 LDCM0358  AC91 HCT 116 C38(0.91); C977(1.03); C651(1.28); C846(1.45)  LDD0675  [11]
 LDCM0359  AC92 HCT 116 C38(0.99); C977(1.06); C846(1.25); C651(1.42)  LDD0676  [11]
 LDCM0360  AC93 HCT 116 C977(0.94); C38(1.08); C426(1.20); C651(1.21)  LDD0677  [11]
 LDCM0361  AC94 HCT 116 C977(0.99); C426(1.11); C38(1.12); C846(1.26)  LDD0678  [11]
 LDCM0362  AC95 HCT 116 C977(0.85); C426(0.86); C360(1.00); C651(1.07)  LDD0679  [11]
 LDCM0363  AC96 HCT 116 C977(0.92); C38(0.95); C846(1.12); C651(1.26)  LDD0680  [11]
 LDCM0364  AC97 HCT 116 C977(1.02); C38(1.24); C846(1.25); C651(1.31)  LDD0681  [11]
 LDCM0365  AC98 HCT 116 C669(0.55); C846(0.61); C977(0.77); C651(1.23)  LDD0682  [11]
 LDCM0366  AC99 HCT 116 C669(0.60); C846(0.71); C426(0.77); C651(0.79)  LDD0683  [11]
 LDCM0248  AKOS034007472 HCT 116 C360(1.10); C426(1.05); C651(0.85); C669(0.85)  LDD0565  [11]
 LDCM0356  AKOS034007680 HCT 116 C651(0.83); C977(0.88); C846(0.91); C669(0.92)  LDD0673  [11]
 LDCM0275  AKOS034007705 HCT 116 C977(1.01); C651(1.02); C846(1.12); C360(1.46)  LDD0592  [11]
 LDCM0020  ARS-1620 HCC44 C651(1.11); C977(0.98)  LDD2171  [11]
 LDCM0632  CL-Sc Hep-G2 C793(20.00); C38(1.63); C426(0.82); C720(0.82)  LDD2227  [5]
 LDCM0367  CL1 HCT 116 C426(0.80); C720(0.82); C651(0.84); C360(0.88)  LDD0684  [11]
 LDCM0368  CL10 HCT 116 C360(0.77); C720(0.85); C38(0.96); C977(1.00)  LDD0685  [11]
 LDCM0369  CL100 HCT 116 C38(0.72); C846(0.82); C514(0.85); C360(0.88)  LDD0686  [11]
 LDCM0370  CL101 HCT 116 C977(0.87); C846(0.90); C651(0.98); C669(1.22)  LDD0687  [11]
 LDCM0371  CL102 HCT 116 C977(0.88); C651(0.91); C846(0.98); C669(1.05)  LDD0688  [11]
 LDCM0372  CL103 HCT 116 C846(0.88); C977(0.89); C651(0.96); C426(0.97)  LDD0689  [11]
 LDCM0373  CL104 HCT 116 C977(0.84); C846(0.88); C651(0.96); C669(0.98)  LDD0690  [11]
 LDCM0374  CL105 HCT 116 C977(0.86); C846(1.04); C720(1.07); C651(1.12)  LDD0691  [11]
 LDCM0375  CL106 HCT 116 C977(0.92); C846(1.19); C651(1.27); C720(1.33)  LDD0692  [11]
 LDCM0376  CL107 HCT 116 C977(0.90); C846(1.10); C514(1.15); C720(1.16)  LDD0693  [11]
 LDCM0377  CL108 HCT 116 C977(0.96); C720(1.20); C846(1.29); C651(1.32)  LDD0694  [11]
 LDCM0378  CL109 HCT 116 C977(0.80); C720(0.90); C846(0.93); C651(0.96)  LDD0695  [11]
 LDCM0379  CL11 HCT 116 C360(0.88); C720(0.93); C38(0.99); C977(1.04)  LDD0696  [11]
 LDCM0380  CL110 HCT 116 C977(0.88); C846(0.98); C720(1.20); C514(1.21)  LDD0697  [11]
 LDCM0381  CL111 HCT 116 C977(0.85); C846(1.08); C651(1.10); C426(1.15)  LDD0698  [11]
 LDCM0382  CL112 HCT 116 C846(0.89); C38(0.91); C720(1.01); C977(1.07)  LDD0699  [11]
 LDCM0383  CL113 HCT 116 C38(0.87); C846(1.00); C720(1.01); C977(1.23)  LDD0700  [11]
 LDCM0384  CL114 HCT 116 C846(0.80); C38(0.81); C720(1.02); C651(1.12)  LDD0701  [11]
 LDCM0385  CL115 HCT 116 C38(0.93); C846(0.95); C720(1.05); C651(1.07)  LDD0702  [11]
 LDCM0386  CL116 HCT 116 C846(0.85); C38(0.88); C720(0.89); C977(1.08)  LDD0703  [11]
 LDCM0387  CL117 HCT 116 C651(0.87); C720(1.01); C360(1.12); C977(1.19)  LDD0704  [11]
 LDCM0388  CL118 HCT 116 C720(0.87); C846(0.97); C977(0.97); C360(0.99)  LDD0705  [11]
 LDCM0389  CL119 HCT 116 C720(0.88); C846(0.99); C651(0.99); C360(1.05)  LDD0706  [11]
 LDCM0390  CL12 HCT 116 C38(0.84); C720(0.87); C977(0.94); C360(0.98)  LDD0707  [11]
 LDCM0391  CL120 HCT 116 C426(0.85); C720(0.85); C669(0.87); C846(0.87)  LDD0708  [11]
 LDCM0392  CL121 HCT 116 C846(0.67); C669(0.68); C426(0.75); C38(0.77)  LDD0709  [11]
 LDCM0393  CL122 HCT 116 C38(0.73); C669(0.95); C846(1.05); C426(1.07)  LDD0710  [11]
 LDCM0394  CL123 HCT 116 C38(0.94); C360(0.98); C669(1.01); C426(1.08)  LDD0711  [11]
 LDCM0395  CL124 HCT 116 C669(0.64); C38(0.94); C360(1.15); C846(1.20)  LDD0712  [11]
 LDCM0396  CL125 HCT 116 C846(0.81); C977(0.87); C651(0.97); C38(1.80)  LDD0713  [11]
 LDCM0397  CL126 HCT 116 C651(0.95); C846(1.16); C977(1.25); C38(1.57)  LDD0714  [11]
 LDCM0398  CL127 HCT 116 C977(0.85); C651(0.99); C846(1.03); C38(1.53)  LDD0715  [11]
 LDCM0399  CL128 HCT 116 C977(0.81); C846(1.06); C651(1.13); C38(1.26)  LDD0716  [11]
 LDCM0400  CL13 HCT 116 C720(0.80); C38(0.83); C651(0.87); C360(0.90)  LDD0717  [11]
 LDCM0401  CL14 HCT 116 C38(0.90); C977(0.91); C720(0.93); C426(0.94)  LDD0718  [11]
 LDCM0402  CL15 HCT 116 C720(0.80); C360(0.82); C977(0.84); C426(0.96)  LDD0719  [11]
 LDCM0403  CL16 HCT 116 C846(0.91); C977(0.91); C38(1.11); C426(1.13)  LDD0720  [11]
 LDCM0404  CL17 HCT 116 C720(0.80); C977(0.91); C426(1.02); C514(1.06)  LDD0721  [11]
 LDCM0405  CL18 HCT 116 C977(0.92); C846(0.93); C426(1.05); C38(1.06)  LDD0722  [11]
 LDCM0406  CL19 HCT 116 C977(0.85); C846(0.86); C38(1.10); C651(1.11)  LDD0723  [11]
 LDCM0407  CL2 HCT 116 C38(0.78); C651(0.83); C720(0.83); C360(0.84)  LDD0724  [11]
 LDCM0408  CL20 HCT 116 C977(0.96); C846(1.05); C38(1.07); C651(1.09)  LDD0725  [11]
 LDCM0409  CL21 HCT 116 C38(0.96); C977(0.97); C720(1.11); C669(1.36)  LDD0726  [11]
 LDCM0410  CL22 HCT 116 C38(0.99); C977(1.19); C846(1.38); C720(1.48)  LDD0727  [11]
 LDCM0411  CL23 HCT 116 C38(0.92); C977(1.00); C720(1.02); C846(1.13)  LDD0728  [11]
 LDCM0412  CL24 HCT 116 C977(0.94); C38(0.96); C720(0.99); C846(1.05)  LDD0729  [11]
 LDCM0413  CL25 HCT 116 C38(0.94); C426(1.34); C514(1.51); C651(1.31)  LDD0730  [11]
 LDCM0414  CL26 HCT 116 C38(1.12); C426(1.21); C514(1.36); C651(1.19)  LDD0731  [11]
 LDCM0415  CL27 HCT 116 C38(1.05); C426(1.00); C514(1.42); C651(1.11)  LDD0732  [11]
 LDCM0416  CL28 HCT 116 C38(1.11); C426(1.25); C514(1.14); C651(1.60)  LDD0733  [11]
 LDCM0417  CL29 HCT 116 C38(1.15); C426(1.40); C514(1.51); C651(1.40)  LDD0734  [11]
 LDCM0418  CL3 HCT 116 C360(0.74); C38(0.80); C426(0.96); C651(0.93)  LDD0735  [11]
 LDCM0419  CL30 HCT 116 C38(1.00); C426(1.13); C514(1.16); C651(1.27)  LDD0736  [11]
 LDCM0420  CL31 HCT 116 C360(0.83); C38(1.48); C426(1.26); C651(0.95)  LDD0737  [11]
 LDCM0421  CL32 HCT 116 C360(0.83); C38(1.17); C426(1.17); C651(1.19)  LDD0738  [11]
 LDCM0422  CL33 HCT 116 C360(0.95); C38(1.00); C426(1.09); C651(1.22)  LDD0739  [11]
 LDCM0423  CL34 HCT 116 C360(0.93); C38(0.65); C426(1.88); C651(1.24)  LDD0740  [11]
 LDCM0424  CL35 HCT 116 C360(1.28); C38(1.03); C426(2.06); C651(1.25)  LDD0741  [11]
 LDCM0425  CL36 HCT 116 C360(1.08); C38(0.86); C426(1.72); C651(1.18)  LDD0742  [11]
 LDCM0426  CL37 HCT 116 C360(1.16); C38(1.16); C426(2.07); C651(1.10)  LDD0743  [11]
 LDCM0428  CL39 HCT 116 C360(0.99); C38(1.18); C426(1.71); C651(1.09)  LDD0745  [11]
 LDCM0429  CL4 HCT 116 C360(0.84); C38(0.75); C426(0.87); C651(1.08)  LDD0746  [11]
 LDCM0430  CL40 HCT 116 C360(1.38); C38(0.86); C426(1.74); C651(0.94)  LDD0747  [11]
 LDCM0431  CL41 HCT 116 C360(0.98); C38(1.11); C426(1.64); C651(1.00)  LDD0748  [11]
 LDCM0432  CL42 HCT 116 C360(1.06); C38(0.89); C426(2.63); C651(0.95)  LDD0749  [11]
 LDCM0433  CL43 HCT 116 C360(1.03); C38(0.91); C426(2.16); C651(1.05)  LDD0750  [11]
 LDCM0434  CL44 HCT 116 C360(0.99); C38(0.99); C426(1.56); C651(1.09)  LDD0751  [11]
 LDCM0435  CL45 HCT 116 C360(0.95); C38(1.27); C426(1.59); C651(1.38)  LDD0752  [11]
 LDCM0436  CL46 HCT 116 C360(0.92); C38(0.73); C426(0.69); C651(0.84)  LDD0753  [11]
 LDCM0437  CL47 HCT 116 C360(0.95); C38(0.85); C426(0.73); C651(0.89)  LDD0754  [11]
 LDCM0438  CL48 HCT 116 C360(0.80); C38(0.70); C426(0.78); C651(0.98)  LDD0755  [11]
 LDCM0439  CL49 HCT 116 C360(1.00); C38(0.86); C426(1.00); C651(1.04)  LDD0756  [11]
 LDCM0440  CL5 HCT 116 C360(0.80); C38(0.73); C426(1.03); C651(0.89)  LDD0757  [11]
 LDCM0441  CL50 HCT 116 C360(0.95); C38(0.77); C426(0.77); C651(0.91)  LDD0758  [11]
 LDCM0442  CL51 HCT 116 C360(0.98); C38(0.89); C426(0.75); C651(0.88)  LDD0759  [11]
 LDCM0443  CL52 HCT 116 C360(1.01); C38(0.74); C426(0.76); C651(0.96)  LDD0760  [11]
 LDCM0444  CL53 HCT 116 C360(1.11); C38(0.70); C426(0.76); C651(0.97)  LDD0761  [11]
 LDCM0445  CL54 HCT 116 C360(0.95); C38(0.62); C426(0.62); C651(0.87)  LDD0762  [11]
 LDCM0446  CL55 HCT 116 C360(0.95); C38(0.67); C426(0.75); C651(0.79)  LDD0763  [11]
 LDCM0447  CL56 HCT 116 C360(0.98); C38(1.00); C426(0.94); C651(0.97)  LDD0764  [11]
 LDCM0448  CL57 HCT 116 C360(1.00); C38(0.61); C426(0.68); C651(0.88)  LDD0765  [11]
 LDCM0449  CL58 HCT 116 C360(1.01); C38(0.81); C426(0.79); C651(0.96)  LDD0766  [11]
 LDCM0450  CL59 HCT 116 C360(0.96); C38(0.95); C426(0.88); C651(0.97)  LDD0767  [11]
 LDCM0451  CL6 HCT 116 C360(0.80); C38(0.84); C426(0.87); C651(1.17)  LDD0768  [11]
 LDCM0452  CL60 HCT 116 C360(0.99); C38(1.08); C426(1.01); C651(0.90)  LDD0769  [11]
 LDCM0453  CL61 HCT 116 C360(1.06); C38(1.31); C426(1.03); C651(1.19)  LDD0770  [11]
 LDCM0454  CL62 HCT 116 C360(0.97); C38(0.95); C426(0.96); C651(1.08)  LDD0771  [11]
 LDCM0455  CL63 HCT 116 C360(0.98); C38(1.14); C426(0.99); C651(1.01)  LDD0772  [11]
 LDCM0456  CL64 HCT 116 C360(1.25); C38(0.95); C426(1.32); C651(1.13)  LDD0773  [11]
 LDCM0457  CL65 HCT 116 C360(1.07); C38(1.03); C426(1.11); C651(1.11)  LDD0774  [11]
 LDCM0458  CL66 HCT 116 C360(1.40); C38(0.95); C426(1.58); C651(0.99)  LDD0775  [11]
 LDCM0459  CL67 HCT 116 C360(1.34); C38(1.04); C426(1.57); C651(0.96)  LDD0776  [11]
 LDCM0460  CL68 HCT 116 C360(1.20); C38(0.94); C426(1.07); C651(1.22)  LDD0777  [11]
 LDCM0461  CL69 HCT 116 C360(1.10); C38(1.12); C426(0.78); C651(1.08)  LDD0778  [11]
 LDCM0462  CL7 HCT 116 C360(0.74); C38(1.06); C426(1.24); C651(1.23)  LDD0779  [11]
 LDCM0463  CL70 HCT 116 C360(1.17); C38(1.05); C426(1.04); C651(1.21)  LDD0780  [11]
 LDCM0464  CL71 HCT 116 C360(1.07); C38(1.07); C426(1.10); C651(1.10)  LDD0781  [11]
 LDCM0465  CL72 HCT 116 C360(1.09); C38(1.10); C426(0.94); C651(1.09)  LDD0782  [11]
 LDCM0466  CL73 HCT 116 C360(1.18); C38(1.27); C426(1.22); C651(1.03)  LDD0783  [11]
 LDCM0467  CL74 HCT 116 C360(1.21); C38(0.94); C426(1.21); C651(1.02)  LDD0784  [11]
 LDCM0469  CL76 HCT 116 C360(0.89); C38(0.96); C426(1.05); C514(0.87)  LDD0786  [11]
 LDCM0470  CL77 HCT 116 C360(0.84); C38(0.95); C426(1.33); C514(0.96)  LDD0787  [11]
 LDCM0471  CL78 HCT 116 C360(0.81); C38(1.06); C426(1.11); C514(1.10)  LDD0788  [11]
 LDCM0472  CL79 HCT 116 C360(1.00); C38(0.86); C426(1.57); C514(1.12)  LDD0789  [11]
 LDCM0473  CL8 HCT 116 C360(1.78); C38(0.89); C426(1.56); C651(1.20)  LDD0790  [11]
 LDCM0474  CL80 HCT 116 C360(0.92); C38(0.91); C426(1.13); C514(0.65)  LDD0791  [11]
 LDCM0475  CL81 HCT 116 C360(0.91); C38(0.96); C426(1.22); C514(0.95)  LDD0792  [11]
 LDCM0476  CL82 HCT 116 C360(1.11); C38(0.97); C426(1.80); C514(1.05)  LDD0793  [11]
 LDCM0477  CL83 HCT 116 C360(0.88); C38(0.95); C426(1.68); C514(0.75)  LDD0794  [11]
 LDCM0478  CL84 HCT 116 C360(0.98); C38(0.88); C426(2.28); C514(0.85)  LDD0795  [11]
 LDCM0479  CL85 HCT 116 C360(0.79); C38(0.89); C426(1.26); C514(0.84)  LDD0796  [11]
 LDCM0480  CL86 HCT 116 C360(0.78); C38(1.05); C426(1.11); C514(0.96)  LDD0797  [11]
 LDCM0481  CL87 HCT 116 C360(0.73); C38(0.93); C426(1.19); C514(0.86)  LDD0798  [11]
 LDCM0482  CL88 HCT 116 C360(0.90); C38(0.92); C426(1.43); C514(1.04)  LDD0799  [11]
 LDCM0483  CL89 HCT 116 C360(1.20); C38(0.96); C426(2.73); C514(0.75)  LDD0800  [11]
 LDCM0484  CL9 HCT 116 C360(0.80); C38(0.83); C426(1.25); C651(0.93)  LDD0801  [11]
 LDCM0485  CL90 HCT 116 C360(0.93); C38(0.81); C426(0.79); C514(0.69)  LDD0802  [11]
 LDCM0486  CL91 HCT 116 C360(0.90); C38(0.95); C426(1.02); C514(0.71)  LDD0803  [11]
 LDCM0487  CL92 HCT 116 C360(1.10); C38(0.82); C426(1.02); C514(0.76)  LDD0804  [11]
 LDCM0488  CL93 HCT 116 C360(0.78); C38(0.87); C426(1.05); C514(1.06)  LDD0805  [11]
 LDCM0489  CL94 HCT 116 C360(0.98); C38(0.82); C426(1.11); C514(0.82)  LDD0806  [11]
 LDCM0490  CL95 HCT 116 C360(1.03); C38(0.88); C426(1.13); C514(0.89)  LDD0807  [11]
 LDCM0491  CL96 HCT 116 C360(1.00); C38(0.92); C426(1.08); C514(0.87)  LDD0808  [11]
 LDCM0492  CL97 HCT 116 C360(0.96); C38(0.94); C426(1.22); C514(0.82)  LDD0809  [11]
 LDCM0493  CL98 HCT 116 C360(1.05); C38(0.92); C426(1.22); C514(1.00)  LDD0810  [11]
 LDCM0494  CL99 HCT 116 C360(1.15); C38(1.05); C426(1.15); C514(1.16)  LDD0811  [11]
 LDCM0634  CY-0357 Hep-G2 C1011(2.10); C720(1.15); C669(0.77); C542(0.32)  LDD2228  [5]
 LDCM0495  E2913 HEK-293T C651(1.10); C360(0.93); C977(1.06); C657(0.97)  LDD1698  [12]
 LDCM0468  Fragment33 HCT 116 C360(1.31); C38(0.92); C426(1.12); C651(1.14)  LDD0785  [11]
 LDCM0427  Fragment51 HCT 116 C360(2.13); C38(0.76); C426(2.22); C651(1.35)  LDD0744  [11]
 LDCM0022  KB02 HEK-293T C38(0.95); C720(1.00); C651(0.93); C360(1.16)  LDD1492  [12]
 LDCM0023  KB03 Jurkat C846(19.63); C651(5.91); C1065(5.10)  LDD0209  [3]
 LDCM0024  KB05 COLO792 C977(4.01)  LDD3310  [13]
 LDCM0021  THZ1 HCT 116 C651(1.11); C977(0.98)  LDD2173  [11]

References

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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD029255
8 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
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Mass spectrometry data entry: PXD041587
10 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
11 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
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Mass spectrometry data entry: PXD044402
13 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840