Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C289  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 177 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 99.7
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 99.7
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 99.7
 LDTP10796  Ribosomal protein S6 kinase delta-1 (RPS6KC1) 99.7
 LDTP10020  Ras-related protein Rab-24 (RAB24) 95.0
 LDTP10981  Mitochondrial intermediate peptidase (MIPEP) 82.7
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 80.4
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 80.4
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 79.9
 LDTP11127  ADP-dependent glucokinase (ADPGK) 79.3
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 77.7
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 77.7
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 77.7
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 77.2
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 76.1
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 75.6
 LDTP06986  Rab-like protein 3 (RABL3) 74.0
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 70.5
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 66.3
 LDTP09251  Atlastin-2 (ATL2) 64.4
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 63.6
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 62.7
 LDTP09285  Atypical kinase COQ8A, mitochondrial (COQ8A) 62.2
 LDTP12197  Ethanolamine kinase 1 (ETNK1) 61.0
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 58.1
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 57.3
 LDTP01803  Adenosine deaminase (ADA) 56.5
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 55.7
 LDTP01513  NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) 54.6
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 53.8
 LDTP03145  Catechol O-methyltransferase (COMT) 52.3
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 51.6
 LDTP04318  Glycogen synthase kinase-3 alpha (GSK3A) 49.9
 LDTP10286  Corrinoid adenosyltransferase MMAB (MMAB) 48.8
 LDTP03540  Heme oxygenase 2 (HMOX2) 48.5
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 47.8
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 47.8
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 47.8
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 47.5
 LDTP05776  Serine/threonine-protein kinase PAK 2 (PAK2) 47.5
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 47.5
 LDTP01502  NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) 46.5
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 46.5
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 45.9
 LDTP09053  Xyloside xylosyltransferase 1 (XXYLT1) 44.9
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 44.6
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 44.3
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 44.3
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 44.0
 LDTP11284  Phosphatidylserine synthase 2 (PTDSS2) 44.0
 LDTP00344  Stearoyl-CoA desaturase (SCD) 44.0
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 43.7
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 43.7
 LDTP10329  Ceramide synthase 2 (CERS2) 43.1
 LDTP12757  E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) 42.8
 LDTP07966  COP9 signalosome complex subunit 6 (COPS6) 42.5
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 42.5
 LDTP08177  Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) 41.9
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 41.9
 LDTP00400  Torsin-1B (TOR1B) 41.9
 LDTP04581  Holocytochrome c-type synthase (HCCS) 41.6
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 41.1
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 39.4
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 39.4
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 39.1
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 39.1
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 39.1
 LDTP12586  Phenylalanine--tRNA ligase beta subunit (FARSB) 38.6
 LDTP16258  N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL) 38.1
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 38.1
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 38.1
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 38.1
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 37.8
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 37.3
 LDTP12752  NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial (NDUFB11) 37.3
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 37.3
 LDTP05408  Antigen peptide transporter 1 (TAP1) 37.0
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 37.0
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 36.8
 LDTP00416  CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) 36.5
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 36.5
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 36.3
 LDTP05228  Calcium-transporting ATPase type 2C member 1 (ATP2C1) 36.3
 LDTP07931  Heme A synthase COX15 (COX15) 36.3
 LDTP05769  Serine/threonine-protein kinase PAK 1 (PAK1) 36.3
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 36.0
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 36.0
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 36.0
 LDTP11606  Ethanolaminephosphotransferase 1 (SELENOI) 35.8
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 35.3
 LDTP01329  Lathosterol oxidase (SC5D) 35.0
 LDTP09578  Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) 35.0
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 34.8
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 34.8
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 34.5
 LDTP09835  GPI-anchor transamidase (PIGK) 34.5
 LDTP09355  Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C) 34.5
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 34.1
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 34.1
 LDTP01168  NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) 33.8
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 33.8
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 33.6
 LDTP08598  NAD-dependent protein deacetylase sirtuin-2 (SIRT2) 33.4
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 33.4
 LDTP06750  Prolyl 3-hydroxylase 1 (P3H1) 33.4
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 33.1
 LDTP02359  Heme oxygenase 1 (HMOX1) 33.1
 LDTP06142  Squalene monooxygenase (SQLE) 33.1
 LDTP04319  Glycogen synthase kinase-3 beta (GSK3B) 32.7
 LDTP11259  Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) 32.4
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 32.4
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 32.2
 LDTP05736  Bifunctional coenzyme A synthase (COASY) 32.2
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 32.2
 LDTP04531  Hexokinase-2 (HK2) 32.2
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 32.0
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 32.0
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 31.8
 LDTP02149  Cyclin-dependent kinase 1 (CDK1) 31.6
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 31.6
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 31.3
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 31.3
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 31.1
 LDTP00399  Torsin-1A (TOR1A) 31.1
 LDTP05905  Acid ceramidase (ASAH1) 30.9
 LDTP03813  Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) 30.7
 LDTP00589  Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) 30.5
 LDTP04895  Ras-related protein Rab-10 (RAB10) 30.3
 LDTP08530  Mitofusin-1 (MFN1) 30.1
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 30.1
 LDTP12494  Carbohydrate sulfotransferase 12 (CHST12) 29.9
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 29.9
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 29.9
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 29.9
 LDTP06720  Peroxisomal leader peptide-processing protease (TYSND1) 29.7
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 29.7
 LDTP14189  UbiA prenyltransferase domain-containing protein 1 (UBIAD1) 29.2
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 29.0
 LDTP00577  Dihydroxyacetone phosphate acyltransferase (GNPAT) 28.8
 LDTP04620  5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) 28.6
 LDTP10432  ATP synthase membrane subunit K, mitochondrial (ATP5MK) 28.6
 LDTP14231  GTP-binding protein SAR1b (SAR1B) 28.6
 LDTP04689  Adenosine kinase (ADK) 28.4
 LDTP02367  Cytochrome c oxidase subunit 6C (COX6C) 28.1
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 28.1
 LDTP02679  Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) 28.1
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 27.9
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 27.7
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 27.5
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 27.5
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 27.3
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 27.3
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 27.1
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 27.1
 LDTP07756  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) 27.1
 LDTP08687  tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) 26.9
 LDTP14278  Sulfide:quinone oxidoreductase, mitochondrial (SQOR) 26.7
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 26.5
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 26.5
 LDTP03050  Ras-related protein Rab-5A (RAB5A) 26.5
 LDTP06384  Ribosomal protein S6 kinase alpha-1 (RPS6KA1) 26.5
 LDTP11867  UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) 26.5
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 26.4
 LDTP02640  X-ray repair cross-complementing protein 6 (XRCC6) 26.4
 LDTP00831  NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) 26.0
 LDTP10973  Thioredoxin, mitochondrial (TXN2) 26.0
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 25.6
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 25.6
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 25.6
 LDTP03769  Sterol O-acyltransferase 1 (SOAT1) 25.6
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 25.5
 LDTP03319  3-mercaptopyruvate sulfurtransferase (MPST) 25.1
 LDTP00899  Exostosin-like 3 (EXTL3) 25.1
Transporter and channel
Click to Show/Hide to Show 150 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15648  BRI3-binding protein (BRI3BP) 99.7
 LDTP16163  Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP11245  Derlin-1 (DERL1) 99.7
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 99.7
 LDTP11927  Essential MCU regulator, mitochondrial (SMDT1) 99.7
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 99.7
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 99.7
 LDTP20002  Transmembrane protein 160 (TMEM160) 99.7
 LDTP10065  Transmembrane protein 230 (TMEM230) 99.7
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 98.4
 LDTP05900  Metaxin-1 (MTX1) 95.0
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 93.1
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 91.8
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 87.4
 LDTP11250  MICOS complex subunit MIC26 (APOO) 86.8
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 85.0
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 84.4
 LDTP11626  Protein YIPF3 (YIPF3) 82.7
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 81.0
 LDTP06275  Lysosomal-associated transmembrane protein 4A (LAPTM4A) 80.4
 LDTP15733  Solute carrier family 25 member 44 (SLC25A44) 78.2
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 76.6
 LDTP16813  Tetraspanin-3 (TSPAN3) 74.5
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 73.5
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 72.0
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 69.1
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 67.2
 LDTP14636  Solute carrier family 25 member 16 (SLC25A16) 67.2
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 62.2
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 60.1
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 60.1
 LDTP07236  Protein GPR107 (GPR107) 58.1
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 56.9
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 56.1
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 55.3
 LDTP06633  Reticulon-1 (RTN1) 55.3
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 53.8
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 53.8
 LDTP13953  Endophilin-B1 (SH3GLB1) 53.4
 LDTP08881  Transmembrane protein 199 (TMEM199) 53.4
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 52.7
 LDTP03405  Calnexin (CANX) 52.7
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 52.7
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 52.0
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 50.9
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 50.6
 LDTP15481  Transmembrane protein 87A (TMEM87A) 50.6
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 49.9
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 49.2
 LDTP07667  Transmembrane protein 205 (TMEM205) 48.8
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 48.5
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 48.2
 LDTP13256  SUN domain-containing protein 2 (SUN2) 47.2
 LDTP04597  Methylosome subunit pICln (CLNS1A) 45.9
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 45.9
 LDTP14181  Peroxisomal membrane protein PEX16 (PEX16) 45.6
 LDTP01160  Peroxisomal membrane protein 11A (PEX11A) 45.3
 LDTP10621  Sideroflexin-2 (SFXN2) 44.9
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 44.3
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 44.0
 LDTP00857  Syntaxin-6 (STX6) 43.7
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 43.4
 LDTP01804  ATP synthase subunit a (MT-ATP6) 43.1
 LDTP07152  Acyl-CoA-binding domain-containing protein 5 (ACBD5) 42.8
 LDTP11812  Protein ARV1 (ARV1) 42.8
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 42.2
 LDTP13833  Integral membrane protein 2B (ITM2B) 42.2
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 42.2
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 42.2
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 41.4
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 41.4
 LDTP09204  Nucleoporin NUP35 (NUP35) 40.8
 LDTP02215  Prosaposin (PSAP) 40.5
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 40.5
 LDTP10931  Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) 40.2
 LDTP07477  Transmembrane protein 214 (TMEM214) 39.9
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 39.7
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 39.7
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 39.7
 LDTP01217  Metaxin-2 (MTX2) 39.4
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 38.9
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 38.3
 LDTP11844  Protein spinster homolog 1 (SPNS1) 38.1
 LDTP14970  Metaxin-3 (MTX3) 37.8
 LDTP11406  Transmembrane protein 59 (TMEM59) 37.5
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 37.3
 LDTP01380  Wolframin (WFS1) 36.5
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 36.3
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 36.0
 LDTP15744  Transmembrane protein 101 (TMEM101) 35.8
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 35.0
 LDTP09948  Peroxisomal membrane protein PEX13 (PEX13) 35.0
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 35.0
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 34.3
 LDTP10036  BOS complex subunit NCLN (NCLN) 34.1
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 33.8
 LDTP00590  Protein RER1 (RER1) 33.1
 LDTP07058  Transmembrane protein 201 (TMEM201) 32.7
 LDTP03546  Translocator protein (TSPO) 32.2
 LDTP11281  Voltage-gated monoatomic cation channel TMEM109 (TMEM109) 32.2
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 32.0
 LDTP04749  Peroxisomal biogenesis factor 3 (PEX3) 32.0
 LDTP01060  PRA1 family protein 2 (PRAF2) 32.0
 LDTP09789  Transmembrane 9 superfamily member 4 (TM9SF4) 31.6
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 31.3
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 31.3
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 31.3
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 31.1
 LDTP15967  Tetraspanin-10 (TSPAN10) 30.9
 LDTP00127  Nuclear envelope pore membrane protein POM 121C (POM121C) 30.7
 LDTP15979  Transmembrane protein 245 (TMEM245) 30.7
 LDTP05871  Protein OS-9 (OS9) 30.5
 LDTP12704  Anoctamin-10 (ANO10) 30.3
 LDTP12979  Transmembrane protein 14C (TMEM14C) 30.1
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 29.9
 LDTP12383  Protein GPR108 (GPR108) 29.9
 LDTP07531  Sideroflexin-4 (SFXN4) 29.9
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 29.7
 LDTP12958  ER membrane protein complex subunit 3 (EMC3) 29.4
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 29.4
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 29.4
 LDTP11615  Protein tweety homolog 3 (TTYH3) 29.2
 LDTP01309  Renin receptor (ATP6AP2) 28.8
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 28.4
 LDTP09144  Metal transporter CNNM3 (CNNM3) 28.2
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 28.2
 LDTP00592  Surfeit locus protein 4 (SURF4) 28.1
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 27.9
 LDTP12191  Vezatin (VEZT) 27.5
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 27.3
 LDTP14275  Sodium bicarbonate cotransporter 3 (SLC4A7) 27.1
 LDTP07361  Bridge-like lipid transfer protein family member 3A (BLTP3A) 26.7
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 26.5
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 26.4
 LDTP11291  Transmembrane emp24 domain-containing protein 9 (TMED9) 26.4
 LDTP08673  Calcium uptake protein 2, mitochondrial (MICU2) 26.2
 LDTP15838  Translocation protein SEC62 (SEC62) 26.0
 LDTP01352  PRA1 family protein 3 (ARL6IP5) 25.8
 LDTP04553  Tricarboxylate transport protein, mitochondrial (SLC25A1) 25.8
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 25.6
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 25.5
 LDTP06855  Anoctamin-6 (ANO6) 25.3
 LDTP00014  Extended synaptotagmin-2 (ESYT2) 25.3
 LDTP04624  Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) 25.3
 LDTP04501  Importin subunit alpha-1 (KPNA2) 25.1
 LDTP04213  Phosphatidylinositol transfer protein beta isoform (PITPNB) 25.1
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 25.1
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 39.4
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 30.5
 LDTP14205  Neuroplastin (NPTN) 28.2
Other
Click to Show/Hide to Show 139 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP12982  Mitochondrial import receptor subunit TOM7 homolog (TOMM7) 99.7
 LDTP16006  Optic atrophy 3 protein (OPA3) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP02345  Retinol-binding protein 1 (RBP1) 99.7
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 99.7
 LDTP15599  UPF0729 protein C18orf32 (C18orf32) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 95.7
 LDTP13086  Syntaxin-18 (STX18) 89.3
 LDTP10056  Protein FAM162A (FAM162A) 83.9
 LDTP06948  Protein YIF1B (YIF1B) 83.3
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 81.0
 LDTP05160  Nucleobindin-2 (NUCB2) 79.3
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 78.8
 LDTP13797  HIG1 domain family member 1A, mitochondrial (HIGD1A) 77.7
 LDTP02736  Myosin light chain 6B (MYL6B) 77.7
 LDTP08224  Protein LYRIC (MTDH) 77.7
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 76.6
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 76.6
 LDTP16080  Protein FAM114A2 (FAM114A2) 72.0
 LDTP08594  Negative elongation factor C/D (NELFCD) 70.5
 LDTP10116  Lipid droplet assembly factor 1 (LDAF1) 69.6
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 69.6
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 67.6
 LDTP12412  Reticulon-4 (RTN4) 65.3
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 64.0
 LDTP18883  Protein CEBPZOS (CEBPZOS) 64.0
 LDTP00986  Syntaxin-10 (STX10) 61.4
 LDTP11113  Receptor expression-enhancing protein 2 (REEP2) 60.5
 LDTP01167  Reticulon-2 (RTN2) 60.1
 LDTP19963  TraB domain-containing protein (TRABD) 60.1
 LDTP13214  UPF0449 protein C19orf25 (C19orf25) 56.5
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 55.7
 LDTP16078  Heme-binding protein 1 (HEBP1) 55.3
 LDTP11076  Apolipoprotein L2 (APOL2) 54.2
 LDTP13922  Tudor and KH domain-containing protein (TDRKH) 54.2
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 53.8
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 53.4
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 52.7
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 52.3
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 51.6
 LDTP10849  Regulator of microtubule dynamics protein 3 (RMDN3) 50.6
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 48.8
 LDTP00397  Golgi SNAP receptor complex member 2 (GOSR2) 48.5
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 48.2
 LDTP10357  RUS family member 1 (RUSF1) 47.2
 LDTP15887  Lipase maturation factor 2 (LMF2) 46.5
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 46.2
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 46.2
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 46.2
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 45.9
 LDTP10275  Mitochondrial potassium channel (CCDC51) 45.9
 LDTP00859  Synaptogyrin-2 (SYNGR2) 44.3
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 43.7
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 43.4
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 43.1
 LDTP14277  Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) 42.5
 LDTP06097  Reticulocalbin-2 (RCN2) 42.5
 LDTP08606  Nurim (NRM) 42.2
 LDTP09773  Protein FAM3C (FAM3C) 42.2
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 41.6
 LDTP09970  RNA-binding protein with multiple splicing (RBPMS) 41.6
 LDTP14458  Tetraspanin-6 (TSPAN6) 41.6
 LDTP01163  Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) 41.6
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 39.9
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 39.9
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 38.9
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 38.3
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 38.1
 LDTP04853  Eukaryotic translation initiation factor 3 subunit E (EIF3E) 37.5
 LDTP01494  Protein YIF1A (YIF1A) 37.5
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 37.5
 LDTP17652  Uncharacterized protein KIAA2013 (KIAA2013) 37.5
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 37.3
 LDTP10381  Peroxisomal membrane protein 11C (PEX11G) 37.3
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 37.0
 LDTP19859  Small integral membrane protein 12 (SMIM12) 36.5
 LDTP14259  Testis-expressed protein 264 (TEX264) 36.0
 LDTP14716  ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) 35.8
 LDTP10093  Mitochondrial calcium uniporter regulator 1 (MCUR1) 35.5
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 35.3
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 35.3
 LDTP15915  Large ribosomal subunit protein uL13m (MRPL13) 35.0
 LDTP09215  Torsin-1A-interacting protein 2 (TOR1AIP2) 35.0
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 34.8
 LDTP17157  OCIA domain-containing protein 2 (OCIAD2) 34.3
 LDTP09806  UBX domain-containing protein 4 (UBXN4) 34.1
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 33.6
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 33.4
 LDTP13517  Paraneoplastic antigen Ma2 (PNMA2) 33.4
 LDTP12476  Translation initiation factor eIF2B subunit gamma (EIF2B3) 33.1
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 32.9
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 32.7
 LDTP12746  Gem-associated protein 8 (GEMIN8) 32.7
 LDTP10452  Conserved oligomeric Golgi complex subunit 3 (COG3) 32.4
 LDTP10924  Prohibitin-2 (PHB2) 32.4
 LDTP04356  Emerin (EMD) 32.2
 LDTP14125  Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) 32.0
 LDTP02297  Vimentin (VIM) 32.0
 LDTP05277  Protein SET (SET) 31.8
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 31.3
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 30.5
 LDTP03729  General transcription factor IIF subunit 1 (GTF2F1) 30.3
 LDTP10403  DDRGK domain-containing protein 1 (DDRGK1) 30.1
 LDTP13560  Vang-like protein 2 (VANGL2) 29.9
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 29.7
 LDTP09644  m-AAA protease-interacting protein 1, mitochondrial (MAIP1) 29.7
 LDTP06413  Microtubule-associated protein RP/EB family member 2 (MAPRE2) 29.7
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 29.4
 LDTP05960  Trophoblast glycoprotein (TPBG) 29.2
 LDTP17659  ELMO domain-containing protein 2 (ELMOD2) 29.0
 LDTP16285  Transducin beta-like protein 2 (TBL2) 28.6
 LDTP01174  Protein NipSnap homolog 2 (NIPSNAP2) 28.1
 LDTP08248  NLR family member X1 (NLRX1) 27.9
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 27.9
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 27.7
 LDTP18272  Transmembrane protein 209 (TMEM209) 27.5
 LDTP02180  Neurofilament light polypeptide (NEFL) 27.3
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 26.9
 LDTP04714  Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) 26.7
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 26.7
 LDTP15863  Large ribosomal subunit protein mL45 (MRPL45) 26.5
 LDTP18132  Protein FAM136A (FAM136A) 26.5
 LDTP04626  UV excision repair protein RAD23 homolog A (RAD23A) 26.5
 LDTP03926  Centrin-2 (CETN2) 26.4
 LDTP10184  HAUS augmin-like complex subunit 1 (HAUS1) 25.8
 LDTP06191  LRP chaperone MESD (MESD) 25.8
 LDTP00105  Protein unc-119 homolog B (UNC119B) 25.8
 LDTP14792  Small ribosomal subunit protein uS9m (MRPS9) 25.6
 LDTP05375  Nucleobindin-1 (NUCB1) 25.5
 LDTP11167  Protein YIPF4 (YIPF4) 25.5
 LDTP15634  Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) 25.5
 LDTP01359  Dynactin subunit 3 (DCTN3) 25.3
 LDTP08058  Mitochondrial antiviral-signaling protein (MAVS) 25.3
 LDTP13273  Ubiquilin-2 (UBQLN2) 25.3
 LDTP09325  Iron-sulfur cluster transfer protein NUBPL (NUBPL) 25.1
 LDTP06892  Protein Hikeshi (HIKESHI) 25.1
 LDTP03775  RNA-binding protein FUS (FUS) 25.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587