General Information of Probe

Probe ID
LDPC0495
Probe Name
C264
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 348.406
Lipid-water partition coefficient (xlogp) 3.9548
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H20N4O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])c2c(OC([H])([H])c3c([H])c([H])c([H])c([H])c3[H])nc([H])c([H])c2[H])N=N1
InChI
InChI=1S/C20H20N4O2/c1-2-3-12-20(23-24-20)13-11-18(25)22-17-10-7-14-21-19(17)26-15-16-8-5-4-6-9-16/h1,4-10,14H,3,11-13,15H2,(H,22,25)
InChIKey
WCHXCTVJGQGMTI-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

110 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
5'-3' exonuclease PLD3 (PLD3) LDTP08476 28.05  LDD1935 
Acid ceramidase (ASAH1) LDTP05905 63.56  LDD1935 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 20.25  LDD1935 
Adenosine deaminase (ADA) LDTP01803 57.68  LDD1935 
ADP-dependent glucokinase (ADPGK) LDTP11127 28.05  LDD1935 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 47.18  LDD1935 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 20.39  LDD1935 
Atlastin-2 (ATL2) LDTP09251 17.63  LDD1935 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 16.68  LDD1935 
ATPase GET3 (GET3) LDTP00836 22.94  LDD1935 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 17.39  LDD1935 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 32.45  LDD1935 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 18.25  LDD1935 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 32.67  LDD1935 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 20.97  LDD1935 
Catechol O-methyltransferase (COMT) LDTP03145 18.38  LDD1935 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 42.81  LDD1935 
Ceramide glucosyltransferase (UGCG) LDTP06617 45.89  LDD1935 
Ceramide synthase 1 (CERS1) LDTP03394 17.03  LDD1935 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 18.90  LDD1935 
Choline kinase alpha (CHKA) LDTP03787 18.77  LDD1935 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 41.36  LDD1935 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 50.21  LDD1935 
Cytochrome b5 type B (CYB5B) LDTP00697 52.35  LDD1935 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 27.10  LDD1935 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 17.27  LDD1935 
DCN1-like protein 5 (DCUN1D5) LDTP11199 28.44  LDD1935 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 25.63  LDD1935 
Delta(24)-sterol reductase (DHCR24) LDTP06375 29.04  LDD1935 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 20.11  LDD1935 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 16.45  LDD1935 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 16.34  LDD1935 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 30.91  LDD1935 
Dynamin-2 (DNM2) LDTP04374 18.38  LDD1935 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 26.54  LDD1935 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 28.05  LDD1935 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 18.25  LDD1935 
Ethanolamine kinase 1 (ETNK1) LDTP12197 23.92  LDD1935 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 42.22  LDD1935 
Ferrochelatase, mitochondrial (FECH) LDTP03198 39.12  LDD1935 
Fumarylacetoacetase (FAH) LDTP02868 21.56  LDD1935 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 19.29  LDD1935 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 36.50  LDD1935 
Heme A synthase COX15 (COX15) LDTP07931 42.52  LDD1935 
Heme oxygenase 1 (HMOX1) LDTP02359 61.82  LDD1935 
Heme oxygenase 2 (HMOX2) LDTP03540 85.04  LDD1935 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 21.71  LDD1935 
Holocytochrome c-type synthase (HCCS) LDTP04581 29.04  LDD1935 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 37.79  LDD1935 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 19.03  LDD1935 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 40.22  LDD1935 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 25.81  LDD1935 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 20.68  LDD1935 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 24.93  LDD1935 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 16.22  LDD1935 
Lysosomal protective protein (CTSA) LDTP02505 18.90  LDD1935 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 24.42  LDD1935 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 23.26  LDD1935 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 18.77  LDD1935 
Minor histocompatibility antigen H13 (HM13) LDTP09396 29.04  LDD1935 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 18.90  LDD1935 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 25.63  LDD1935 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 25.46  LDD1935 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 23.59  LDD1935 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 31.78  LDD1935 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 28.25  LDD1935 
NADP-dependent malic enzyme (ME1) LDTP04164 38.85  LDD1935 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 32.00  LDD1935 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 52.35  LDD1935 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 23.26  LDD1935 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 19.43  LDD1935 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 17.75  LDD1935 
Pirin (PIR) LDTP00325 50.91  LDD1935 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 18.77  LDD1935 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 28.25  LDD1935 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 22.63  LDD1935 
Prostaglandin reductase 3 (PTGR3) LDTP15422 19.16  LDD1935 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 24.59  LDD1935 
Protein arginine N-methyltransferase 9 (PRMT9) LDTP07525 48.84  LDD1935 
Protein O-GlcNAcase (OGA) LDTP00988 16.45  LDD1935 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 18.38  LDD1935 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 28.05  LDD1935 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 20.68  LDD1935 
Ras-related protein Rab-11B (RAB11B) LDTP06501 26.35  LDD1935 
Ras-related protein Rab-1B (RAB1B) LDTP11733 17.27  LDD1935 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 37.27  LDD1935 
Retinol dehydrogenase 13 (RDH13) LDTP09061 17.15  LDD1935 
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) LDTP07989 23.92  LDD1935 
rRNA methyltransferase 3, mitochondrial (MRM3) LDTP12215 17.88  LDD1935 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 26.72  LDD1935 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 18.25  LDD1935 
Selenocysteine-specific elongation factor (EEFSEC) LDTP14723 17.03  LDD1935 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 17.63  LDD1935 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 58.89  LDD1935 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 36.00  LDD1935 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 18.64  LDD1935 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 33.36  LDD1935 
Squalene monooxygenase (SQLE) LDTP06142 18.13  LDD1935 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 16.91  LDD1935 
Synaptobrevin homolog YKT6 (YKT6) LDTP00654 17.03  LDD1935 
Thimet oligopeptidase (THOP1) LDTP04542 19.84  LDD1935 
TLC domain-containing protein 1 (TLCD1) LDTP10182 19.29  LDD1935 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 17.27  LDD1935 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 29.24  LDD1935 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 18.77  LDD1935 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 24.25  LDD1935 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 16.34  LDD1935 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 17.88  LDD1935 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 35.02  LDD1935 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 24.42  LDD1935 
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⏷ Show the Full List of 110 Enzyme
95 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 30.70  LDD1935 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 17.39  LDD1935 
Anoctamin-10 (ANO10) LDTP12704 16.45  LDD1935 
Anoctamin-6 (ANO6) LDTP06855 17.39  LDD1935 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 24.76  LDD1935 
ATP synthase subunit a (MT-ATP6) LDTP01804 34.78  LDD1935 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 46.21  LDD1935 
BRI3-binding protein (BRI3BP) LDTP15648 47.18  LDD1935 
Cationic amino acid transporter 2 (SLC7A2) LDTP04512 16.91  LDD1935 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 21.86  LDD1935 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 18.25  LDD1935 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 40.79  LDD1935 
Derlin-1 (DERL1) LDTP11245 27.10  LDD1935 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 25.11  LDD1935 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 28.84  LDD1935 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 27.28  LDD1935 
Gasdermin-E (GSDME) LDTP00970 23.26  LDD1935 
Glucose-6-phosphate exchanger SLC37A4 (SLC37A4) LDTP00882 17.27  LDD1935 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 19.97  LDD1935 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 18.00  LDD1935 
Guided entry of tail-anchored proteins factor CAMLG (CAMLG) LDTP04227 16.56  LDD1935 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 24.08  LDD1935 
Importin-7 (IPO7) LDTP01574 25.99  LDD1935 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 20.97  LDD1935 
Lysosome membrane protein 2 (SCARB2) LDTP06034 29.65  LDD1935 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 26.91  LDD1935 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 21.26  LDD1935 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 44.94  LDD1935 
Metaxin-1 (MTX1) LDTP05900 42.81  LDD1935 
MICOS complex subunit MIC26 (APOO) LDTP11250 22.01  LDD1935 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 17.51  LDD1935 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 23.75  LDD1935 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 21.56  LDD1935 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 33.59  LDD1935 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 30.06  LDD1935 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 43.41  LDD1935 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 72.00  LDD1935 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 86.22  LDD1935 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 39.40  LDD1935 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 21.56  LDD1935 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 22.63  LDD1935 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 20.39  LDD1935 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 16.68  LDD1935 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 44.02  LDD1935 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 17.27  LDD1935 
Mpv17-like protein 2 (MPV17L2) LDTP14952 39.95  LDD1935 
Nucleoporin NUP35 (NUP35) LDTP09204 39.12  LDD1935 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 21.86  LDD1935 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 28.44  LDD1935 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 18.38  LDD1935 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 19.03  LDD1935 
Prosaposin (PSAP) LDTP02215 38.32  LDD1935 
Protein FAM8A1 (FAM8A1) LDTP16190 18.64  LDD1935 
Protein GPR107 (GPR107) LDTP07236 34.06  LDD1935 
Protein SEC13 homolog (SEC13) LDTP04707 16.68  LDD1935 
Protein spinster homolog 1 (SPNS1) LDTP11844 29.65  LDD1935 
Protein tweety homolog 3 (TTYH3) LDTP11615 27.86  LDD1935 
Protein wntless homolog (WLS) LDTP07156 18.25  LDD1935 
Protein YIPF3 (YIPF3) LDTP11626 19.43  LDD1935 
Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) LDTP07610 18.38  LDD1935 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 29.45  LDD1935 
Reticulon-1 (RTN1) LDTP06633 69.55  LDD1935 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 22.63  LDD1935 
Sideroflexin-4 (SFXN4) LDTP07531 26.72  LDD1935 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 23.92  LDD1935 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 54.19  LDD1935 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 37.27  LDD1935 
Sorting nexin-19 (SNX19) LDTP09788 26.35  LDD1935 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 19.70  LDD1935 
Sugar transporter SWEET1 (SLC50A1) LDTP11136 16.68  LDD1935 
Surfeit locus protein 4 (SURF4) LDTP00592 24.08  LDD1935 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 17.51  LDD1935 
Syntaxin-6 (STX6) LDTP00857 37.53  LDD1935 
Tetraspanin-10 (TSPAN10) LDTP15967 27.28  LDD1935 
Tetraspanin-3 (TSPAN3) LDTP16813 77.71  LDD1935 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 23.43  LDD1935 
Translocator protein (TSPO) LDTP03546 21.86  LDD1935 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 82.71  LDD1935 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 22.01  LDD1935 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 59.71  LDD1935 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 34.06  LDD1935 
Transmembrane protein 126A (TMEM126A) LDTP15948 57.28  LDD1935 
Transmembrane protein 160 (TMEM160) LDTP20002 99.73  LDD1935 
Transmembrane protein 199 (TMEM199) LDTP08881 99.73  LDD1935 
Transmembrane protein 201 (TMEM201) LDTP07058 18.51  LDD1935 
Transmembrane protein 205 (TMEM205) LDTP07667 16.91  LDD1935 
Transmembrane protein 230 (TMEM230) LDTP10065 21.71  LDD1935 
Transmembrane protein 87A (TMEM87A) LDTP15481 36.00  LDD1935 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 30.06  LDD1935 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 18.77  LDD1935 
Vang-like protein 1 (VANGL1) LDTP09288 16.91  LDD1935 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 50.21  LDD1935 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 36.76  LDD1935 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 21.26  LDD1935 
Wolframin (WFS1) LDTP01380 16.22  LDD1935 
------------------------------------------------------------------------------------
⏷ Show the Full List of 95 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 24.76  LDD1935 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Leukocyte surface antigen CD47 (CD47) LDTP05572 17.03  LDD1935 
------------------------------------------------------------------------------------
79 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 16.56  LDD1935 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1935 
Armadillo repeat-containing protein 6 (ARMC6) LDTP15101 19.29  LDD1935 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 19.16  LDD1935 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 19.84  LDD1935 
BSD domain-containing protein 1 (BSDC1) LDTP16116 33.82  LDD1935 
Calpain small subunit 1 (CAPNS1) LDTP02047 17.39  LDD1935 
Centrin-2 (CETN2) LDTP03926 17.15  LDD1935 
Centrosomal protein 43 (CEP43) LDTP01652 19.03  LDD1935 
Clustered mitochondria protein homolog (CLUH) LDTP14486 33.59  LDD1935 
Condensin complex subunit 2 (NCAPH) LDTP06268 16.56  LDD1935 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 72.50  LDD1935 
Dymeclin (DYM) LDTP08000 21.41  LDD1935 
Dynactin subunit 3 (DCTN3) LDTP01359 19.16  LDD1935 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 20.68  LDD1935 
Dystonin (DST) LDTP05386 42.52  LDD1935 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 56.89  LDD1935 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 45.57  LDD1935 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 28.84  LDD1935 
Ganglioside GM2 activator (GM2A) LDTP02927 21.11  LDD1935 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 29.24  LDD1935 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 17.39  LDD1935 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 19.56  LDD1935 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 43.41  LDD1935 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 44.94  LDD1935 
Kinetochore protein Spc24 (SPC24) LDTP09069 17.63  LDD1935 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 20.68  LDD1935 
Large proline-rich protein BAG6 (BAG6) LDTP04094 19.16  LDD1935 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 28.25  LDD1935 
Membralin (TMEM259) LDTP14939 63.56  LDD1935 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 23.26  LDD1935 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 64.45  LDD1935 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1935 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 42.81  LDD1935 
Negative elongation factor C/D (NELFCD) LDTP08594 17.15  LDD1935 
Nucleobindin-1 (NUCB1) LDTP05375 20.11  LDD1935 
Nucleobindin-2 (NUCB2) LDTP05160 85.04  LDD1935 
Nurim (NRM) LDTP08606 34.54  LDD1935 
Optic atrophy 3 protein (OPA3) LDTP16006 35.75  LDD1935 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 28.05  LDD1935 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 25.28  LDD1935 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 18.77  LDD1935 
Protein FAM114A2 (FAM114A2) LDTP16080 41.93  LDD1935 
Protein FAM162A (FAM162A) LDTP10056 48.84  LDD1935 
Protein FAM177A1 (FAM177A1) LDTP15398 16.80  LDD1935 
Protein FAM3C (FAM3C) LDTP09773 28.25  LDD1935 
Protein jagunal homolog 1 (JAGN1) LDTP08904 16.91  LDD1935 
Protein kish-B (TMEM167B) LDTP12545 17.39  LDD1935 
Protein LYRIC (MTDH) LDTP08224 32.67  LDD1935 
Protein misato homolog 1 (MSTO1) LDTP11239 17.15  LDD1935 
Protein unc-119 homolog A (UNC119) LDTP05868 21.71  LDD1935 
Protein unc-119 homolog B (UNC119B) LDTP00105 30.48  LDD1935 
Protein YIF1A (YIF1A) LDTP01494 17.39  LDD1935 
Reticulocalbin-2 (RCN2) LDTP06097 16.34  LDD1935 
Reticulon-3 (RTN3) LDTP01522 45.89  LDD1935 
Reticulon-4 (RTN4) LDTP12412 35.26  LDD1935 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 38.59  LDD1935 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 17.03  LDD1935 
Small integral membrane protein 12 (SMIM12) LDTP19859 19.29  LDD1935 
Splicing factor ESS-2 homolog (ESS2) LDTP10214 16.91  LDD1935 
Superkiller complex protein 3 (SKIC3) LDTP07574 28.05  LDD1935 
Syntaxin-10 (STX10) LDTP00986 28.84  LDD1935 
Syntaxin-18 (STX18) LDTP13086 34.06  LDD1935 
Tetraspanin-6 (TSPAN6) LDTP14458 36.00  LDD1935 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 32.67  LDD1935 
TraB domain-containing protein (TRABD) LDTP19963 24.25  LDD1935 
Transducin beta-like protein 2 (TBL2) LDTP16285 18.00  LDD1935 
Transmembrane protein 11, mitochondrial (TMEM11) LDTP02887 17.39  LDD1935 
Tubulin beta chain (TUBB) LDTP02205 78.79  LDD1935 
Tubulin beta-2A chain (TUBB2A) LDTP05998 72.00  LDD1935 
Tubulin beta-2B chain (TUBB2B) LDTP11277 99.73  LDD1935 
Tubulin beta-4A chain (TUBB4A) LDTP02037 53.82  LDD1935 
Tubulin beta-4B chain (TUBB4B) LDTP05076 86.22  LDD1935 
Tubulin beta-6 chain (TUBB6) LDTP11233 85.63  LDD1935 
Tumor protein D52 (TPD52) LDTP04703 17.27  LDD1935 
Ubiquilin-2 (UBQLN2) LDTP13273 17.75  LDD1935 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 70.52  LDD1935 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 18.00  LDD1935 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 18.00  LDD1935 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587