Details of the Probe

General Information of Probe

Probe ID
LDPC0515
Probe Name
C285
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 338.411
Lipid-water partition coefficient (xlogp) 3.2751
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H22N4O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])C2([H])C(=O)N([H])c3c([H])c([H])c(C([H])(C([H])([H])[H])C([H])([H])[H])c([H])c32)N=N1
InChI
InChI=1S/C19H22N4O2/c1-4-5-9-19(22-23-19)10-8-16(24)21-17-14-11-13(12(2)3)6-7-15(14)20-18(17)25/h1,6-7,11-12,17H,5,8-10H2,2-3H3,(H,20,25)(H,21,24)/t17-/m0/s1
InChIKey
LOXAMVKDCZIJHS-KRWDZBQOSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

105 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) LDTP00543 19.43  LDD1955 
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 27.28  LDD1955 
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) LDTP04620 22.78  LDD1955 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 22.01  LDD1955 
ADP-dependent glucokinase (ADPGK) LDTP11127 60.13  LDD1955 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 70.03  LDD1955 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 48.84  LDD1955 
Antigen peptide transporter 1 (TAP1) LDTP05408 20.97  LDD1955 
Atlastin-2 (ATL2) LDTP09251 25.11  LDD1955 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 21.26  LDD1955 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 20.53  LDD1955 
ATPase GET3 (GET3) LDTP00836 19.97  LDD1955 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 25.63  LDD1955 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 41.07  LDD1955 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 53.82  LDD1955 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 21.56  LDD1955 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 22.94  LDD1955 
Catechol O-methyltransferase (COMT) LDTP03145 43.41  LDD1955 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 99.73  LDD1955 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 19.84  LDD1955 
Cell cycle checkpoint control protein RAD9A (RAD9A) LDTP10929 20.97  LDD1955 
Ceramide synthase 2 (CERS2) LDTP10329 25.28  LDD1955 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 52.71  LDD1955 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 20.53  LDD1955 
Corrinoid adenosyltransferase MMAB (MMAB) LDTP10286 20.39  LDD1955 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 92.41  LDD1955 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 27.86  LDD1955 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1955 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 20.97  LDD1955 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 20.39  LDD1955 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 23.92  LDD1955 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 24.42  LDD1955 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 22.63  LDD1955 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 65.80  LDD1955 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 22.94  LDD1955 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 34.54  LDD1955 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 32.00  LDD1955 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 26.54  LDD1955 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 24.59  LDD1955 
Ethanolamine kinase 1 (ETNK1) LDTP12197 26.35  LDD1955 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 19.43  LDD1955 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 19.16  LDD1955 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 19.16  LDD1955 
Heme A synthase COX15 (COX15) LDTP07931 20.39  LDD1955 
Heme oxygenase 1 (HMOX1) LDTP02359 25.11  LDD1955 
Heme oxygenase 2 (HMOX2) LDTP03540 62.25  LDD1955 
Hexokinase-2 (HK2) LDTP04531 23.75  LDD1955 
Holocytochrome c-type synthase (HCCS) LDTP04581 20.53  LDD1955 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 40.79  LDD1955 
Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 25.11  LDD1955 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 21.56  LDD1955 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 62.25  LDD1955 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 26.91  LDD1955 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 28.25  LDD1955 
Macrophage migration inhibitory factor (MIF) LDTP02713 20.68  LDD1955 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 23.43  LDD1955 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 38.59  LDD1955 
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL) LDTP16258 20.97  LDD1955 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 22.16  LDD1955 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 34.78  LDD1955 
NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial (NDUFB11) LDTP12752 19.29  LDD1955 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD1955 
NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 19.29  LDD1955 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 29.04  LDD1955 
NADPH--cytochrome P450 reductase (POR) LDTP02848 19.70  LDD1955 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 20.82  LDD1955 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 24.76  LDD1955 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 22.47  LDD1955 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 22.16  LDD1955 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 26.17  LDD1955 
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) LDTP09578 21.11  LDD1955 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 21.71  LDD1955 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 19.97  LDD1955 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 20.68  LDD1955 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 48.84  LDD1955 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 21.26  LDD1955 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 20.25  LDD1955 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 28.05  LDD1955 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 19.16  LDD1955 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 29.24  LDD1955 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 20.11  LDD1955 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 36.76  LDD1955 
Rab-like protein 3 (RABL3) LDTP06986 41.64  LDD1955 
Ras-related protein Rab-10 (RAB10) LDTP04895 19.43  LDD1955 
Ras-related protein Rab-11B (RAB11B) LDTP06501 25.28  LDD1955 
Ras-related protein Rab-18 (RAB18) LDTP12312 20.39  LDD1955 
Ras-related protein Rab-24 (RAB24) LDTP10020 22.63  LDD1955 
Retinol dehydrogenase 13 (RDH13) LDTP09061 25.81  LDD1955 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 23.10  LDD1955 
Separin (ESPL1) LDTP06175 31.56  LDD1955 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 39.67  LDD1955 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 43.41  LDD1955 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 28.64  LDD1955 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 26.54  LDD1955 
Squalene monooxygenase (SQLE) LDTP06142 20.97  LDD1955 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 19.56  LDD1955 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 19.84  LDD1955 
Thimet oligopeptidase (THOP1) LDTP04542 20.97  LDD1955 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 39.40  LDD1955 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 31.56  LDD1955 
tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) LDTP08687 20.53  LDD1955 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 24.93  LDD1955 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 19.16  LDD1955 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 19.70  LDD1955 
Xyloside xylosyltransferase 1 (XXYLT1) LDTP09053 41.07  LDD1955 
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⏷ Show the Full List of 105 Enzyme
95 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 39.67  LDD1955 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 29.04  LDD1955 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 24.76  LDD1955 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 22.78  LDD1955 
Anoctamin-10 (ANO10) LDTP12704 25.28  LDD1955 
ATP synthase subunit a (MT-ATP6) LDTP01804 28.05  LDD1955 
ATP synthase subunit d, mitochondrial (ATP5PD) LDTP14509 19.16  LDD1955 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 71.51  LDD1955 
BRI3-binding protein (BRI3BP) LDTP15648 99.73  LDD1955 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 23.59  LDD1955 
Calnexin (CANX) LDTP03405 20.68  LDD1955 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 21.56  LDD1955 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 99.73  LDD1955 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 26.17  LDD1955 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 28.25  LDD1955 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1955 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 25.11  LDD1955 
Derlin-1 (DERL1) LDTP11245 56.49  LDD1955 
Endophilin-B1 (SH3GLB1) LDTP13953 21.56  LDD1955 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 25.81  LDD1955 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 24.25  LDD1955 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 24.59  LDD1955 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 53.08  LDD1955 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 36.50  LDD1955 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 38.59  LDD1955 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 25.63  LDD1955 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 28.25  LDD1955 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 34.06  LDD1955 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 29.86  LDD1955 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 32.00  LDD1955 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 97.68  LDD1955 
Metaxin-1 (MTX1) LDTP05900 50.21  LDD1955 
Methylosome subunit pICln (CLNS1A) LDTP04597 24.59  LDD1955 
MICOS complex subunit MIC26 (APOO) LDTP11250 38.05  LDD1955 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 19.16  LDD1955 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 26.17  LDD1955 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 39.95  LDD1955 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 60.55  LDD1955 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 39.12  LDD1955 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 39.40  LDD1955 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 53.08  LDD1955 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 64.89  LDD1955 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 57.68  LDD1955 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 49.87  LDD1955 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 22.78  LDD1955 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 27.28  LDD1955 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 26.91  LDD1955 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 46.53  LDD1955 
Nuclear envelope pore membrane protein POM 121C (POM121C) LDTP00127 19.84  LDD1955 
Nucleoporin NDC1 (NDC1) LDTP11213 19.29  LDD1955 
Nucleoporin NUP35 (NUP35) LDTP09204 22.32  LDD1955 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 42.22  LDD1955 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 30.06  LDD1955 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 23.75  LDD1955 
PRA1 family protein 2 (PRAF2) LDTP01060 22.01  LDD1955 
Protein ARV1 (ARV1) LDTP11812 29.86  LDD1955 
Protein GPR107 (GPR107) LDTP07236 41.93  LDD1955 
Protein GPR108 (GPR108) LDTP12383 23.43  LDD1955 
Protein RER1 (RER1) LDTP00590 28.25  LDD1955 
Protein YIPF3 (YIPF3) LDTP11626 26.72  LDD1955 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 21.41  LDD1955 
Reticulon-1 (RTN1) LDTP06633 30.91  LDD1955 
Solute carrier family 25 member 16 (SLC25A16) LDTP14636 23.43  LDD1955 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 29.86  LDD1955 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 21.71  LDD1955 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 32.67  LDD1955 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 23.92  LDD1955 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 33.36  LDD1955 
SUN domain-containing protein 2 (SUN2) LDTP13256 19.56  LDD1955 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 33.59  LDD1955 
Syntaxin-17 (STX17) LDTP04770 21.56  LDD1955 
Syntaxin-6 (STX6) LDTP00857 20.39  LDD1955 
Tetraspanin-10 (TSPAN10) LDTP15967 21.86  LDD1955 
Tetraspanin-3 (TSPAN3) LDTP16813 33.59  LDD1955 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 21.56  LDD1955 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 35.75  LDD1955 
Translocator protein (TSPO) LDTP03546 22.16  LDD1955 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1955 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 24.08  LDD1955 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 28.64  LDD1955 
Transmembrane protein 126A (TMEM126A) LDTP15948 99.73  LDD1955 
Transmembrane protein 160 (TMEM160) LDTP20002 99.73  LDD1955 
Transmembrane protein 199 (TMEM199) LDTP08881 34.30  LDD1955 
Transmembrane protein 201 (TMEM201) LDTP07058 22.32  LDD1955 
Transmembrane protein 205 (TMEM205) LDTP07667 20.68  LDD1955 
Transmembrane protein 214 (TMEM214) LDTP07477 20.68  LDD1955 
Transmembrane protein 230 (TMEM230) LDTP10065 38.59  LDD1955 
Transmembrane protein 33 (TMEM33) LDTP04787 28.64  LDD1955 
Transmembrane protein 41A (TMEM41A) LDTP18169 21.41  LDD1955 
Transmembrane protein 87A (TMEM87A) LDTP15481 32.67  LDD1955 
Vezatin (VEZT) LDTP12191 21.41  LDD1955 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 38.05  LDD1955 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 44.94  LDD1955 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 38.85  LDD1955 
Wolframin (WFS1) LDTP01380 19.97  LDD1955 
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⏷ Show the Full List of 95 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 20.11  LDD1955 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Leukocyte surface antigen CD47 (CD47) LDTP05572 20.25  LDD1955 
------------------------------------------------------------------------------------
97 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 20.53  LDD1955 
Angiomotin (AMOT) LDTP06868 24.08  LDD1955 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 22.47  LDD1955 
Apolipoprotein L2 (APOL2) LDTP11076 56.10  LDD1955 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 20.68  LDD1955 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 19.43  LDD1955 
CCR4-NOT transcription complex subunit 2 (CNOT2) LDTP12925 25.63  LDD1955 
Centrin-2 (CETN2) LDTP03926 22.01  LDD1955 
Clustered mitochondria protein homolog (CLUH) LDTP14486 22.01  LDD1955 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 21.86  LDD1955 
Conserved oligomeric Golgi complex subunit 3 (COG3) LDTP10452 20.39  LDD1955 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 27.47  LDD1955 
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) LDTP14277 25.46  LDD1955 
DET1- and DDB1-associated protein 1 (DDA1) LDTP11312 83.87  LDD1955 
DNA polymerase epsilon subunit 3 (POLE3) LDTP12506 19.56  LDD1955 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 46.21  LDD1955 
Dymeclin (DYM) LDTP08000 25.46  LDD1955 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 22.78  LDD1955 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 41.36  LDD1955 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 30.91  LDD1955 
Gem-associated protein 8 (GEMIN8) LDTP12746 21.71  LDD1955 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 26.17  LDD1955 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 24.59  LDD1955 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 23.75  LDD1955 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 21.11  LDD1955 
Guanine nucleotide-binding protein G(i) subunit alpha-1 (GNAI1) LDTP05041 22.01  LDD1955 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 19.16  LDD1955 
Heme-binding protein 1 (HEBP1) LDTP16078 22.01  LDD1955 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 19.43  LDD1955 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 30.70  LDD1955 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 36.50  LDD1955 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 21.26  LDD1955 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 30.91  LDD1955 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 20.68  LDD1955 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 55.33  LDD1955 
Lipase maturation factor 2 (LMF2) LDTP15887 24.08  LDD1955 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 33.36  LDD1955 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 26.54  LDD1955 
m-AAA protease-interacting protein 1, mitochondrial (MAIP1) LDTP09644 23.75  LDD1955 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 48.50  LDD1955 
Membralin (TMEM259) LDTP14939 19.84  LDD1955 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 73.01  LDD1955 
MICOS complex subunit MIC27 (APOOL) LDTP07718 20.39  LDD1955 
Mitochondrial calcium uniporter regulator 1 (MCUR1) LDTP10093 19.43  LDD1955 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 27.10  LDD1955 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 23.10  LDD1955 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 65.80  LDD1955 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1955 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 84.45  LDD1955 
Myosin light chain 6B (MYL6B) LDTP02736 27.86  LDD1955 
Nucleobindin-1 (NUCB1) LDTP05375 34.30  LDD1955 
Nucleobindin-2 (NUCB2) LDTP05160 94.35  LDD1955 
Nurim (NRM) LDTP08606 26.91  LDD1955 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 27.67  LDD1955 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 23.10  LDD1955 
Optic atrophy 3 protein (OPA3) LDTP16006 99.73  LDD1955 
Paraneoplastic antigen Ma2 (PNMA2) LDTP13517 19.84  LDD1955 
Peroxisomal membrane protein 11C (PEX11G) LDTP10381 28.44  LDD1955 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 19.16  LDD1955 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 51.63  LDD1955 
PRELI domain-containing protein 1, mitochondrial (PRELID1) LDTP13807 27.28  LDD1955 
Prohibitin-2 (PHB2) LDTP10924 20.11  LDD1955 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 19.56  LDD1955 
Protein CEBPZOS (CEBPZOS) LDTP18883 28.44  LDD1955 
Protein FAM114A2 (FAM114A2) LDTP16080 53.45  LDD1955 
Protein FAM162A (FAM162A) LDTP10056 65.80  LDD1955 
Protein FAM3C (FAM3C) LDTP09773 21.86  LDD1955 
Protein jagunal homolog 1 (JAGN1) LDTP08904 22.47  LDD1955 
Protein LYRIC (MTDH) LDTP08224 58.08  LDD1955 
Protein YIF1A (YIF1A) LDTP01494 22.63  LDD1955 
Protein YIF1B (YIF1B) LDTP06948 34.78  LDD1955 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 25.63  LDD1955 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 19.43  LDD1955 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 40.79  LDD1955 
Reticulocalbin-2 (RCN2) LDTP06097 24.08  LDD1955 
Reticulon-2 (RTN2) LDTP01167 28.44  LDD1955 
Reticulon-3 (RTN3) LDTP01522 76.64  LDD1955 
Reticulon-4 (RTN4) LDTP12412 28.05  LDD1955 
Retinol-binding protein 1 (RBP1) LDTP02345 28.25  LDD1955 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 20.11  LDD1955 
RUS family member 1 (RUSF1) LDTP10357 49.87  LDD1955 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 21.86  LDD1955 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 29.04  LDD1955 
Synaptogyrin-2 (SYNGR2) LDTP00859 22.78  LDD1955 
Syntaxin-10 (STX10) LDTP00986 27.86  LDD1955 
Syntaxin-18 (STX18) LDTP13086 57.28  LDD1955 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 19.56  LDD1955 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 57.68  LDD1955 
TraB domain-containing protein (TRABD) LDTP19963 34.06  LDD1955 
Transducin beta-like protein 2 (TBL2) LDTP16285 20.68  LDD1955 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 27.47  LDD1955 
U2 small nuclear ribonucleoprotein A' (SNRPA1) LDTP02365 19.43  LDD1955 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 26.91  LDD1955 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 20.97  LDD1955 
UPF0449 protein C19orf25 (C19orf25) LDTP13214 46.53  LDD1955 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 65.34  LDD1955 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 29.86  LDD1955 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1955 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587