Details of the Probe

General Information of Probe

Probe ID
LDPC0485
Probe Name
C252
Synonyms
Z4282859620
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 405.5
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C21H23N7O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[6-[(3-methoxyphenyl)methyl]-4-methyl-2H-pyrazolo[3,4-c]pyrazol-3-yl]propanamide
Canonical SMILES
CC1=NN(C2=NNC(=C12)NC(=O)CCC3(N=N3)CCC#C)CC4=CC(=CC=C4)OC
InChI
InChI=1S/C21H23N7O2/c1-4-5-10-21(26-27-21)11-9-17(29)22-19-18-14(2)25-28(20(18)24-23-19)13-15-7-6-8-16(12-15)30-3/h1,6-8,12H,5,9-11,13H2,2-3H3,(H2,22,23,24,29)
InChIKey
XEPHGTPSPCLMBO-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

184 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 1 (HACL1) LDTP13375 9.13  LDD1925 
2-hydroxyacyl-CoA lyase 1 (HACL1) LDTP13375 9.13  LDD1925 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 10.63  LDD1925 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 10.63  LDD1925 
Adenosine kinase (ADK) LDTP04689 10.27  LDD1925 
Adenosine kinase (ADK) LDTP04689 10.27  LDD1925 
ADP-dependent glucokinase (ADPGK) LDTP11127 29.45  LDD1925 
ADP-dependent glucokinase (ADPGK) LDTP11127 29.45  LDD1925 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 18.13  LDD1925 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 18.13  LDD1925 
Antigen peptide transporter 1 (TAP1) LDTP05408 8.57  LDD1925 
Antigen peptide transporter 1 (TAP1) LDTP05408 8.57  LDD1925 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 15.03  LDD1925 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 15.03  LDD1925 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 12.73  LDD1925 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 12.73  LDD1925 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 8.82  LDD1925 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 8.82  LDD1925 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.32  LDD1925 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.32  LDD1925 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 19.56  LDD1925 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 19.56  LDD1925 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 12.64  LDD1925 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 12.64  LDD1925 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 23.59  LDD1925 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 23.59  LDD1925 
Catechol O-methyltransferase (COMT) LDTP03145 11.39  LDD1925 
Catechol O-methyltransferase (COMT) LDTP03145 11.39  LDD1925 
Ceramide glucosyltransferase (UGCG) LDTP06617 10.56  LDD1925 
Ceramide glucosyltransferase (UGCG) LDTP06617 10.56  LDD1925 
Ceramide synthase 2 (CERS2) LDTP10329 32.67  LDD1925 
Ceramide synthase 2 (CERS2) LDTP10329 32.67  LDD1925 
Choline kinase alpha (CHKA) LDTP03787 9.78  LDD1925 
Choline kinase alpha (CHKA) LDTP03787 9.78  LDD1925 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 14.22  LDD1925 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 14.22  LDD1925 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 31.12  LDD1925 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 31.12  LDD1925 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 30.48  LDD1925 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 30.48  LDD1925 
Cytochrome b5 type B (CYB5B) LDTP00697 41.93  LDD1925 
Cytochrome b5 type B (CYB5B) LDTP00697 41.93  LDD1925 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 21.41  LDD1925 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 21.41  LDD1925 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 13.36  LDD1925 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 13.36  LDD1925 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 25.28  LDD1925 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 25.28  LDD1925 
Delta(24)-sterol reductase (DHCR24) LDTP06375 12.21  LDD1925 
Delta(24)-sterol reductase (DHCR24) LDTP06375 12.21  LDD1925 
Dihydrofolate reductase (DHFR) LDTP01769 12.30  LDD1925 
Dihydrofolate reductase (DHFR) LDTP01769 12.30  LDD1925 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.51  LDD1925 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.51  LDD1925 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 15.24  LDD1925 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 15.24  LDD1925 
E3 ubiquitin-protein ligase UBR2 (UBR2) LDTP08565 31.78  LDD1925 
E3 ubiquitin-protein ligase UBR2 (UBR2) LDTP08565 31.78  LDD1925 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 9.92  LDD1925 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 9.92  LDD1925 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 17.63  LDD1925 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 17.63  LDD1925 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 9.71  LDD1925 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 9.71  LDD1925 
Exonuclease 1 (EXO1) LDTP13751 12.91  LDD1925 
Exonuclease 1 (EXO1) LDTP13751 12.91  LDD1925 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 25.46  LDD1925 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 25.46  LDD1925 
Glutaminyl-peptide cyclotransferase-like protein (QPCTL) LDTP12790 11.08  LDD1925 
Glutaminyl-peptide cyclotransferase-like protein (QPCTL) LDTP12790 11.08  LDD1925 
Heme oxygenase 1 (HMOX1) LDTP02359 24.08  LDD1925 
Heme oxygenase 1 (HMOX1) LDTP02359 24.08  LDD1925 
Heme oxygenase 2 (HMOX2) LDTP03540 41.07  LDD1925 
Heme oxygenase 2 (HMOX2) LDTP03540 41.07  LDD1925 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 9.92  LDD1925 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 9.92  LDD1925 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 8.28  LDD1925 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 8.28  LDD1925 
Holocytochrome c-type synthase (HCCS) LDTP04581 11.79  LDD1925 
Holocytochrome c-type synthase (HCCS) LDTP04581 11.79  LDD1925 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 23.43  LDD1925 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 23.43  LDD1925 
Kinesin-like protein KIF14 (KIF14) LDTP06303 9.00  LDD1925 
Kinesin-like protein KIF14 (KIF14) LDTP06303 9.00  LDD1925 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 8.94  LDD1925 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 8.94  LDD1925 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 9.51  LDD1925 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 9.51  LDD1925 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 12.91  LDD1925 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 12.91  LDD1925 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 9.65  LDD1925 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 9.65  LDD1925 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 13.00  LDD1925 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 13.00  LDD1925 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 8.28  LDD1925 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 8.28  LDD1925 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 11.63  LDD1925 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 11.63  LDD1925 
Macrophage migration inhibitory factor (MIF) LDTP02713 8.51  LDD1925 
Macrophage migration inhibitory factor (MIF) LDTP02713 8.51  LDD1925 
Mannose-6-phosphate isomerase (MPI) LDTP03697 9.45  LDD1925 
Mannose-6-phosphate isomerase (MPI) LDTP03697 9.45  LDD1925 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 12.04  LDD1925 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 12.04  LDD1925 
Minor histocompatibility antigen H13 (HM13) LDTP09396 28.84  LDD1925 
Minor histocompatibility antigen H13 (HM13) LDTP09396 28.84  LDD1925 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 12.55  LDD1925 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 12.55  LDD1925 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 13.93  LDD1925 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 13.93  LDD1925 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 9.19  LDD1925 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 9.19  LDD1925 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 24.76  LDD1925 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 24.76  LDD1925 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 28.05  LDD1925 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 28.05  LDD1925 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 17.03  LDD1925 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 17.03  LDD1925 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 8.69  LDD1925 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 8.69  LDD1925 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 16.45  LDD1925 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 16.45  LDD1925 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 8.28  LDD1925 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 8.28  LDD1925 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 8.75  LDD1925 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 8.75  LDD1925 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 16.45  LDD1925 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 16.45  LDD1925 
Presequence protease, mitochondrial (PITRM1) LDTP07003 8.46  LDD1925 
Presequence protease, mitochondrial (PITRM1) LDTP07003 8.46  LDD1925 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 9.00  LDD1925 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 9.00  LDD1925 
Prolyl endopeptidase-like (PREPL) LDTP06849 12.64  LDD1925 
Prolyl endopeptidase-like (PREPL) LDTP06849 12.64  LDD1925 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 8.69  LDD1925 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 8.69  LDD1925 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.32  LDD1925 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.32  LDD1925 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 9.00  LDD1925 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 9.00  LDD1925 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 12.82  LDD1925 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 12.82  LDD1925 
Protein O-GlcNAcase (OGA) LDTP00988 8.46  LDD1925 
Protein O-GlcNAcase (OGA) LDTP00988 8.46  LDD1925 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.56  LDD1925 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.56  LDD1925 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 9.45  LDD1925 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 9.45  LDD1925 
Ras-related protein Rab-24 (RAB24) LDTP10020 10.34  LDD1925 
Ras-related protein Rab-24 (RAB24) LDTP10020 10.34  LDD1925 
Ras-related protein Rab-5B (RAB5B) LDTP04893 8.46  LDD1925 
Ras-related protein Rab-5B (RAB5B) LDTP04893 8.46  LDD1925 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 17.39  LDD1925 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 17.39  LDD1925 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 14.42  LDD1925 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 14.42  LDD1925 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 10.13  LDD1925 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 10.13  LDD1925 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 53.45  LDD1925 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 53.45  LDD1925 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 78.25  LDD1925 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 78.25  LDD1925 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 9.99  LDD1925 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 9.99  LDD1925 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 10.06  LDD1925 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 10.06  LDD1925 
Squalene monooxygenase (SQLE) LDTP06142 9.45  LDD1925 
Squalene monooxygenase (SQLE) LDTP06142 9.45  LDD1925 
Squalene synthase (FDFT1) LDTP03842 30.70  LDD1925 
Squalene synthase (FDFT1) LDTP03842 30.70  LDD1925 
STAM-binding protein (STAMBP) LDTP01641 12.13  LDD1925 
STAM-binding protein (STAMBP) LDTP01641 12.13  LDD1925 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 13.45  LDD1925 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 13.45  LDD1925 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 8.82  LDD1925 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 8.82  LDD1925 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 12.73  LDD1925 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 12.73  LDD1925 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 8.94  LDD1925 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 8.94  LDD1925 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.38  LDD1925 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.38  LDD1925 
Xaa-Arg dipeptidase (PM20D2) LDTP08666 9.38  LDD1925 
Xaa-Arg dipeptidase (PM20D2) LDTP08666 9.38  LDD1925 
------------------------------------------------------------------------------------
⏷ Show the Full List of 184 Enzyme
106 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 16.68  LDD1925 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 16.68  LDD1925 
ATP synthase subunit a (MT-ATP6) LDTP01804 52.35  LDD1925 
ATP synthase subunit a (MT-ATP6) LDTP01804 52.35  LDD1925 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 19.70  LDD1925 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 19.70  LDD1925 
Autophagy-related protein 9A (ATG9A) LDTP08030 8.51  LDD1925 
Autophagy-related protein 9A (ATG9A) LDTP08030 8.51  LDD1925 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 19.84  LDD1925 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 19.84  LDD1925 
Derlin-1 (DERL1) LDTP11245 10.78  LDD1925 
Derlin-1 (DERL1) LDTP11245 10.78  LDD1925 
Derlin-2 (DERL2) LDTP11634 13.00  LDD1925 
Derlin-2 (DERL2) LDTP11634 13.00  LDD1925 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 42.22  LDD1925 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 42.22  LDD1925 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 13.64  LDD1925 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 13.64  LDD1925 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 31.78  LDD1925 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 31.78  LDD1925 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 8.82  LDD1925 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 8.82  LDD1925 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 17.51  LDD1925 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 17.51  LDD1925 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 10.34  LDD1925 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 10.34  LDD1925 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 11.96  LDD1925 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 11.96  LDD1925 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 17.88  LDD1925 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 17.88  LDD1925 
Metaxin-1 (MTX1) LDTP05900 16.34  LDD1925 
Metaxin-1 (MTX1) LDTP05900 16.34  LDD1925 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 9.38  LDD1925 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 9.38  LDD1925 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 9.06  LDD1925 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 9.06  LDD1925 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 9.65  LDD1925 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 9.65  LDD1925 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 20.82  LDD1925 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 20.82  LDD1925 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 8.88  LDD1925 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 8.88  LDD1925 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1925 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1925 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 39.67  LDD1925 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 39.67  LDD1925 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 9.51  LDD1925 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 9.51  LDD1925 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 8.40  LDD1925 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 8.40  LDD1925 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 8.28  LDD1925 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 8.28  LDD1925 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 23.43  LDD1925 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 23.43  LDD1925 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 8.46  LDD1925 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 8.46  LDD1925 
Mpv17-like protein 2 (MPV17L2) LDTP14952 9.78  LDD1925 
Mpv17-like protein 2 (MPV17L2) LDTP14952 9.78  LDD1925 
Nucleoporin NDC1 (NDC1) LDTP11213 13.83  LDD1925 
Nucleoporin NDC1 (NDC1) LDTP11213 13.83  LDD1925 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 10.48  LDD1925 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 10.48  LDD1925 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 16.22  LDD1925 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 16.22  LDD1925 
PRA1 family protein 2 (PRAF2) LDTP01060 13.64  LDD1925 
PRA1 family protein 2 (PRAF2) LDTP01060 13.64  LDD1925 
Protein FAM8A1 (FAM8A1) LDTP16190 15.03  LDD1925 
Protein FAM8A1 (FAM8A1) LDTP16190 15.03  LDD1925 
Protein GPR107 (GPR107) LDTP07236 19.70  LDD1925 
Protein GPR107 (GPR107) LDTP07236 19.70  LDD1925 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.64  LDD1925 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.64  LDD1925 
Reticulon-1 (RTN1) LDTP06633 31.34  LDD1925 
Reticulon-1 (RTN1) LDTP06633 31.34  LDD1925 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 10.27  LDD1925 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 10.27  LDD1925 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 9.51  LDD1925 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 9.51  LDD1925 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 29.04  LDD1925 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 29.04  LDD1925 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 12.91  LDD1925 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 12.91  LDD1925 
SUN domain-containing protein 1 (SUN1) LDTP01454 8.69  LDD1925 
SUN domain-containing protein 1 (SUN1) LDTP01454 8.69  LDD1925 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 14.12  LDD1925 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 14.12  LDD1925 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 32.90  LDD1925 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 32.90  LDD1925 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 11.79  LDD1925 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 11.79  LDD1925 
Transmembrane protein 160 (TMEM160) LDTP20002 19.16  LDD1925 
Transmembrane protein 160 (TMEM160) LDTP20002 19.16  LDD1925 
Transmembrane protein 201 (TMEM201) LDTP07058 9.19  LDD1925 
Transmembrane protein 201 (TMEM201) LDTP07058 9.19  LDD1925 
Transmembrane protein 230 (TMEM230) LDTP10065 10.48  LDD1925 
Transmembrane protein 230 (TMEM230) LDTP10065 10.48  LDD1925 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 15.67  LDD1925 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 15.67  LDD1925 
Vacuole membrane protein 1 (VMP1) LDTP10343 10.63  LDD1925 
Vacuole membrane protein 1 (VMP1) LDTP10343 10.63  LDD1925 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 23.75  LDD1925 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 23.75  LDD1925 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 18.13  LDD1925 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 18.13  LDD1925 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 8.57  LDD1925 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 8.57  LDD1925 
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⏷ Show the Full List of 106 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 9.06  LDD1925 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 9.06  LDD1925 
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98 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 17.39  LDD1925 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 17.39  LDD1925 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 11.96  LDD1925 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 11.96  LDD1925 
Centrosomal protein 43 (CEP43) LDTP01652 10.85  LDD1925 
Centrosomal protein 43 (CEP43) LDTP01652 10.85  LDD1925 
Clustered mitochondria protein homolog (CLUH) LDTP14486 10.48  LDD1925 
Clustered mitochondria protein homolog (CLUH) LDTP14486 10.48  LDD1925 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 10.85  LDD1925 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 10.85  LDD1925 
Cytochrome c oxidase assembly protein COX14 (COX14) LDTP15741 11.31  LDD1925 
Cytochrome c oxidase assembly protein COX14 (COX14) LDTP15741 11.31  LDD1925 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 19.97  LDD1925 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 19.97  LDD1925 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 11.08  LDD1925 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 11.08  LDD1925 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 13.18  LDD1925 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 13.18  LDD1925 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 9.99  LDD1925 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 9.99  LDD1925 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 22.01  LDD1925 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 22.01  LDD1925 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.92  LDD1925 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.92  LDD1925 
Heme-binding protein 1 (HEBP1) LDTP16078 9.78  LDD1925 
Heme-binding protein 1 (HEBP1) LDTP16078 9.78  LDD1925 
Immunoglobulin-binding protein 1 (IGBP1) LDTP05089 10.63  LDD1925 
Immunoglobulin-binding protein 1 (IGBP1) LDTP05089 10.63  LDD1925 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 9.78  LDD1925 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 9.78  LDD1925 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 9.51  LDD1925 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 9.51  LDD1925 
Large proline-rich protein BAG6 (BAG6) LDTP04094 12.21  LDD1925 
Large proline-rich protein BAG6 (BAG6) LDTP04094 12.21  LDD1925 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 18.00  LDD1925 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 18.00  LDD1925 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 76.11  LDD1925 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 76.11  LDD1925 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 35.75  LDD1925 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 35.75  LDD1925 
Neuferricin (CYB5D2) LDTP15623 12.55  LDD1925 
Neuferricin (CYB5D2) LDTP15623 12.55  LDD1925 
Nucleobindin-1 (NUCB1) LDTP05375 13.18  LDD1925 
Nucleobindin-1 (NUCB1) LDTP05375 13.18  LDD1925 
Nucleobindin-2 (NUCB2) LDTP05160 19.56  LDD1925 
Nucleobindin-2 (NUCB2) LDTP05160 19.56  LDD1925 
Nurim (NRM) LDTP08606 11.08  LDD1925 
Nurim (NRM) LDTP08606 11.08  LDD1925 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 8.82  LDD1925 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 8.82  LDD1925 
Optic atrophy 3 protein (OPA3) LDTP16006 21.11  LDD1925 
Optic atrophy 3 protein (OPA3) LDTP16006 21.11  LDD1925 
Programmed cell death protein 5 (PDCD5) LDTP00417 9.00  LDD1925 
Programmed cell death protein 5 (PDCD5) LDTP00417 9.00  LDD1925 
Protein FAM114A2 (FAM114A2) LDTP16080 19.03  LDD1925 
Protein FAM114A2 (FAM114A2) LDTP16080 19.03  LDD1925 
Protein FAM162A (FAM162A) LDTP10056 18.51  LDD1925 
Protein FAM162A (FAM162A) LDTP10056 18.51  LDD1925 
Protein LYRIC (MTDH) LDTP08224 9.00  LDD1925 
Protein LYRIC (MTDH) LDTP08224 9.00  LDD1925 
Protein unc-119 homolog B (UNC119B) LDTP00105 21.26  LDD1925 
Protein unc-119 homolog B (UNC119B) LDTP00105 21.26  LDD1925 
Protein YIF1A (YIF1A) LDTP01494 10.78  LDD1925 
Protein YIF1A (YIF1A) LDTP01494 10.78  LDD1925 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 9.65  LDD1925 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 9.65  LDD1925 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 8.69  LDD1925 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 8.69  LDD1925 
Reticulon-3 (RTN3) LDTP01522 29.86  LDD1925 
Reticulon-3 (RTN3) LDTP01522 29.86  LDD1925 
Reticulon-4 (RTN4) LDTP12412 25.99  LDD1925 
Reticulon-4 (RTN4) LDTP12412 25.99  LDD1925 
RNA binding protein fox-1 homolog 2 (RBFOX2) LDTP00716 10.27  LDD1925 
RNA binding protein fox-1 homolog 2 (RBFOX2) LDTP00716 10.27  LDD1925 
RNA-binding protein EWS (EWSR1) LDTP05318 10.56  LDD1925 
RNA-binding protein EWS (EWSR1) LDTP05318 10.56  LDD1925 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 17.15  LDD1925 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 17.15  LDD1925 
RUS family member 1 (RUSF1) LDTP10357 9.65  LDD1925 
RUS family member 1 (RUSF1) LDTP10357 9.65  LDD1925 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.82  LDD1925 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.82  LDD1925 
Stathmin (STMN1) LDTP02869 9.65  LDD1925 
Stathmin (STMN1) LDTP02869 9.65  LDD1925 
Synaptogyrin-2 (SYNGR2) LDTP00859 10.93  LDD1925 
Synaptogyrin-2 (SYNGR2) LDTP00859 10.93  LDD1925 
Syntaxin-18 (STX18) LDTP13086 10.85  LDD1925 
Syntaxin-18 (STX18) LDTP13086 10.85  LDD1925 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 25.63  LDD1925 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 25.63  LDD1925 
TraB domain-containing protein (TRABD) LDTP19963 15.45  LDD1925 
TraB domain-containing protein (TRABD) LDTP19963 15.45  LDD1925 
Trophoblast glycoprotein (TPBG) LDTP05960 25.46  LDD1925 
Trophoblast glycoprotein (TPBG) LDTP05960 25.46  LDD1925 
Tubulin beta-2B chain (TUBB2B) LDTP11277 9.85  LDD1925 
Tubulin beta-2B chain (TUBB2B) LDTP11277 9.85  LDD1925 
Vimentin (VIM) LDTP02297 8.40  LDD1925 
Vimentin (VIM) LDTP02297 8.40  LDD1925 
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⏷ Show the Full List of 98 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1925 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587