Details of the Probe

General Information of Probe

Probe ID
LDPC0441
Probe Name
C206
Synonyms
Z3337872146
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 385.4
Lipid-water partition coefficient (xlogp) 1.7
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C18H19N5O3S
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-[3-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)morpholin-4-yl]propan-1-one
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CCOCC2C3=NC(=NO3)C4=CC=CS4
InChI
InChI=1S/C18H19N5O3S/c1-2-3-7-18(21-22-18)8-6-15(24)23-9-10-25-12-13(23)17-19-16(20-26-17)14-5-4-11-27-14/h1,4-5,11,13H,3,6-10,12H2
InChIKey
OXAARSJQJLZGHX-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

132 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 17.39  LDD1881 
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 15.56  LDD1881 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 16.45  LDD1881 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 31.34  LDD1881 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 20.25  LDD1881 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 15.24  LDD1881 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 38.85  LDD1881 
Abasic site processing protein HMCES (HMCES) LDTP10322 21.26  LDD1881 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 18.25  LDD1881 
Acid ceramidase (ASAH1) LDTP05905 28.05  LDD1881 
ADP-dependent glucokinase (ADPGK) LDTP11127 19.03  LDD1881 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 41.36  LDD1881 
Alpha-galactosidase A (GLA) LDTP02141 15.24  LDD1881 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.22  LDD1881 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 16.68  LDD1881 
ATPase GET3 (GET3) LDTP00836 15.24  LDD1881 
Beta-galactosidase (GLB1) LDTP02837 18.25  LDD1881 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 25.46  LDD1881 
BRCA1-associated protein (BRAP) LDTP08084 18.25  LDD1881 
Breast cancer type 1 susceptibility protein (BRCA1) LDTP03851 18.38  LDD1881 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 38.85  LDD1881 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 24.93  LDD1881 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 15.35  LDD1881 
Catechol O-methyltransferase (COMT) LDTP03145 19.84  LDD1881 
Ceramide glucosyltransferase (UGCG) LDTP06617 44.02  LDD1881 
Ceramide synthase 2 (CERS2) LDTP10329 29.86  LDD1881 
Ceramide synthase 5 (CERS5) LDTP08891 17.75  LDD1881 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 25.81  LDD1881 
Choline kinase alpha (CHKA) LDTP03787 16.80  LDD1881 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 99.73  LDD1881 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 33.59  LDD1881 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 18.00  LDD1881 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1881 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 86.82  LDD1881 
Cytochrome b5 type B (CYB5B) LDTP00697 78.79  LDD1881 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 37.01  LDD1881 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 37.27  LDD1881 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 15.45  LDD1881 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 20.53  LDD1881 
Delta(24)-sterol reductase (DHCR24) LDTP06375 38.32  LDD1881 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 17.03  LDD1881 
Dihydrofolate reductase (DHFR) LDTP01769 44.02  LDD1881 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 16.11  LDD1881 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 25.28  LDD1881 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 20.25  LDD1881 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 35.51  LDD1881 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 18.90  LDD1881 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 16.80  LDD1881 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 15.24  LDD1881 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 17.15  LDD1881 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 18.64  LDD1881 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 30.48  LDD1881 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 27.10  LDD1881 
Epoxide hydrolase 1 (EPHX1) LDTP02175 47.50  LDD1881 
Fumarylacetoacetase (FAH) LDTP02868 51.27  LDD1881 
Glutathione hydrolase 7 (GGT7) LDTP13367 18.25  LDD1881 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 24.42  LDD1881 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 19.16  LDD1881 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 22.47  LDD1881 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 23.43  LDD1881 
Heme A synthase COX15 (COX15) LDTP07931 17.27  LDD1881 
Heme oxygenase 1 (HMOX1) LDTP02359 79.34  LDD1881 
Heme oxygenase 2 (HMOX2) LDTP03540 99.73  LDD1881 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 50.21  LDD1881 
Hexokinase-2 (HK2) LDTP04531 17.39  LDD1881 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 16.11  LDD1881 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 59.71  LDD1881 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 27.10  LDD1881 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 23.75  LDD1881 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 18.90  LDD1881 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 28.44  LDD1881 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 27.28  LDD1881 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 27.28  LDD1881 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 16.56  LDD1881 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 17.39  LDD1881 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 32.90  LDD1881 
Lysosomal acid phosphatase (ACP2) LDTP02539 18.77  LDD1881 
Lysosomal alpha-glucosidase (GAA) LDTP02486 17.51  LDD1881 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 23.26  LDD1881 
Lysosomal protective protein (CTSA) LDTP02505 37.53  LDD1881 
Methionine aminopeptidase 1 (METAP1) LDTP04565 20.68  LDD1881 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 53.82  LDD1881 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 38.85  LDD1881 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 23.26  LDD1881 
Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) LDTP10038 19.29  LDD1881 
Mitofusin-1 (MFN1) LDTP08530 15.78  LDD1881 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 15.67  LDD1881 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 27.28  LDD1881 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 25.28  LDD1881 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 15.89  LDD1881 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD1881 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 15.67  LDD1881 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 24.08  LDD1881 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 19.43  LDD1881 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 37.27  LDD1881 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 23.10  LDD1881 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 86.22  LDD1881 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 35.51  LDD1881 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 19.84  LDD1881 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 20.39  LDD1881 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 16.56  LDD1881 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 20.39  LDD1881 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 37.53  LDD1881 
Presequence protease, mitochondrial (PITRM1) LDTP07003 18.25  LDD1881 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 23.26  LDD1881 
Prolyl endopeptidase-like (PREPL) LDTP06849 16.11  LDD1881 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 16.34  LDD1881 
Prostaglandin reductase 3 (PTGR3) LDTP15422 17.39  LDD1881 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 24.08  LDD1881 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 21.11  LDD1881 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 32.45  LDD1881 
Protein O-GlcNAcase (OGA) LDTP00988 18.77  LDD1881 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 58.08  LDD1881 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 16.91  LDD1881 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 15.45  LDD1881 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 35.75  LDD1881 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 52.71  LDD1881 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 19.97  LDD1881 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 16.22  LDD1881 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 16.91  LDD1881 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 99.73  LDD1881 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 19.56  LDD1881 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 36.25  LDD1881 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 30.70  LDD1881 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 16.00  LDD1881 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 17.03  LDD1881 
TLC domain-containing protein 1 (TLCD1) LDTP10182 22.47  LDD1881 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 27.10  LDD1881 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 20.25  LDD1881 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 26.54  LDD1881 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 20.82  LDD1881 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 99.73  LDD1881 
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⏷ Show the Full List of 132 Enzyme
69 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 21.11  LDD1881 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 27.67  LDD1881 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 25.46  LDD1881 
Amyloid-beta precursor protein (APP) LDTP02071 19.29  LDD1881 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 47.84  LDD1881 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 45.25  LDD1881 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 32.67  LDD1881 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 18.77  LDD1881 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 79.34  LDD1881 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 28.25  LDD1881 
Derlin-2 (DERL2) LDTP11634 17.88  LDD1881 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 76.11  LDD1881 
ER membrane protein complex subunit 2 (EMC2) LDTP06271 15.24  LDD1881 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 25.28  LDD1881 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 20.39  LDD1881 
Integral membrane protein 2C (ITM2C) LDTP12451 21.26  LDD1881 
Lysosome membrane protein 2 (SCARB2) LDTP06034 27.67  LDD1881 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 59.71  LDD1881 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 51.27  LDD1881 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 20.82  LDD1881 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 55.33  LDD1881 
Metaxin-1 (MTX1) LDTP05900 51.98  LDD1881 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 21.11  LDD1881 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 17.88  LDD1881 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 18.51  LDD1881 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 36.50  LDD1881 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 83.87  LDD1881 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1881 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 40.50  LDD1881 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 24.25  LDD1881 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 18.77  LDD1881 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 68.59  LDD1881 
Mpv17-like protein 2 (MPV17L2) LDTP14952 24.59  LDD1881 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 43.41  LDD1881 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 15.56  LDD1881 
Nucleoporin NDC1 (NDC1) LDTP11213 25.11  LDD1881 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 16.00  LDD1881 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 16.91  LDD1881 
Prosaposin (PSAP) LDTP02215 42.81  LDD1881 
Protein GPR107 (GPR107) LDTP07236 56.49  LDD1881 
Protein Mpv17 (MPV17) LDTP03869 15.56  LDD1881 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 16.91  LDD1881 
Protein spinster homolog 1 (SPNS1) LDTP11844 16.34  LDD1881 
Protein tweety homolog 3 (TTYH3) LDTP11615 37.01  LDD1881 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 23.10  LDD1881 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 29.86  LDD1881 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 43.11  LDD1881 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 19.03  LDD1881 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 37.27  LDD1881 
Solute carrier family 25 member 16 (SLC25A16) LDTP14636 29.65  LDD1881 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 99.73  LDD1881 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 88.03  LDD1881 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 48.17  LDD1881 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 17.15  LDD1881 
Sorting nexin-19 (SNX19) LDTP09788 16.00  LDD1881 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 36.00  LDD1881 
Tetraspanin-3 (TSPAN3) LDTP16813 65.34  LDD1881 
Translocator protein (TSPO) LDTP03546 32.45  LDD1881 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 88.03  LDD1881 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 44.02  LDD1881 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 17.27  LDD1881 
Transmembrane protein 126A (TMEM126A) LDTP15948 99.73  LDD1881 
Transmembrane protein 199 (TMEM199) LDTP08881 41.64  LDD1881 
Transmembrane protein 201 (TMEM201) LDTP07058 16.34  LDD1881 
Transmembrane protein 87A (TMEM87A) LDTP15481 19.16  LDD1881 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 26.17  LDD1881 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 96.34  LDD1881 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 79.89  LDD1881 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 22.16  LDD1881 
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⏷ Show the Full List of 69 Transporter and channel
1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 27.10  LDD1881 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 15.24  LDD1881 
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98 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
A-kinase anchor protein 8-like (AKAP8L) LDTP13591 15.24  LDD1881 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 19.97  LDD1881 
BAG family molecular chaperone regulator 4 (BAG4) LDTP01600 16.00  LDD1881 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 17.75  LDD1881 
Calumenin (CALU) LDTP00887 23.10  LDD1881 
CCR4-NOT transcription complex subunit 9 (CNOT9) LDTP09813 20.97  LDD1881 
Centrin-2 (CETN2) LDTP03926 19.29  LDD1881 
Centromere protein P (CENPP) LDTP07419 21.41  LDD1881 
Centrosomal protein 43 (CEP43) LDTP01652 16.00  LDD1881 
Cleavage stimulation factor subunit 3 (CSTF3) LDTP05719 17.15  LDD1881 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.25  LDD1881 
Collectin-12 (COLEC12) LDTP07031 16.68  LDD1881 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 29.04  LDD1881 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 45.89  LDD1881 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 19.03  LDD1881 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 17.75  LDD1881 
Dynactin subunit 3 (DCTN3) LDTP01359 20.68  LDD1881 
Dynactin subunit 4 (DCTN4) LDTP13402 46.21  LDD1881 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 16.45  LDD1881 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 26.17  LDD1881 
Emerin (EMD) LDTP04356 16.00  LDD1881 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 39.40  LDD1881 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 38.32  LDD1881 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 33.59  LDD1881 
Galectin-3-binding protein (LGALS3BP) LDTP05558 15.89  LDD1881 
Ganglioside GM2 activator (GM2A) LDTP02927 26.72  LDD1881 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 20.39  LDD1881 
Golgi apparatus protein 1 (GLG1) LDTP09920 22.16  LDD1881 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 30.06  LDD1881 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 24.59  LDD1881 
HCLS1-associated protein X-1 (HAX1) LDTP00199 23.43  LDD1881 
Heme-binding protein 1 (HEBP1) LDTP16078 15.67  LDD1881 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 22.01  LDD1881 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 18.00  LDD1881 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 15.56  LDD1881 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 15.56  LDD1881 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 15.67  LDD1881 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 20.82  LDD1881 
Intron Large complex component GCFC2 (GCFC2) LDTP02841 24.93  LDD1881 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 21.56  LDD1881 
Kinetochore protein Nuf2 (NUF2) LDTP11525 16.68  LDD1881 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 20.25  LDD1881 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 17.63  LDD1881 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 54.57  LDD1881 
Membralin (TMEM259) LDTP14939 33.13  LDD1881 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 15.24  LDD1881 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 16.91  LDD1881 
Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) LDTP14125 16.45  LDD1881 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 16.56  LDD1881 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1881 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 34.54  LDD1881 
Neudesin (NENF) LDTP13630 19.29  LDD1881 
Neurofilament medium polypeptide (NEFM) LDTP02181 17.27  LDD1881 
Nicastrin (NCSTN) LDTP09787 16.00  LDD1881 
Nucleobindin-1 (NUCB1) LDTP05375 40.50  LDD1881 
Nucleobindin-2 (NUCB2) LDTP05160 99.73  LDD1881 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 17.27  LDD1881 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 26.91  LDD1881 
Optic atrophy 3 protein (OPA3) LDTP16006 28.84  LDD1881 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 70.52  LDD1881 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 21.71  LDD1881 
Protein CutA (CUTA) LDTP01075 34.78  LDD1881 
Protein FAM114A2 (FAM114A2) LDTP16080 47.84  LDD1881 
Protein FAM162A (FAM162A) LDTP10056 32.00  LDD1881 
Protein Hook homolog 2 (HOOK2) LDTP10255 21.56  LDD1881 
Protein jagunal homolog 1 (JAGN1) LDTP08904 29.45  LDD1881 
Protein SET (SET) LDTP05277 30.48  LDD1881 
Protein SYS1 homolog (SYS1) LDTP08796 20.53  LDD1881 
Protein transport protein Sec23B (SEC23B) LDTP06391 23.75  LDD1881 
Protein YIF1A (YIF1A) LDTP01494 33.59  LDD1881 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 17.39  LDD1881 
RAD50-interacting protein 1 (RINT1) LDTP07476 18.25  LDD1881 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 21.86  LDD1881 
Reticulocalbin-2 (RCN2) LDTP06097 25.46  LDD1881 
Reticulon-3 (RTN3) LDTP01522 58.89  LDD1881 
Reticulon-4 (RTN4) LDTP12412 41.07  LDD1881 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 17.15  LDD1881 
RNA-binding protein 3 (RBM3) LDTP05226 15.78  LDD1881 
RNA-binding protein FUS (FUS) LDTP03775 15.78  LDD1881 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 19.29  LDD1881 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 15.24  LDD1881 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 21.11  LDD1881 
Synaptogyrin-2 (SYNGR2) LDTP00859 24.08  LDD1881 
Syntaxin-10 (STX10) LDTP00986 27.47  LDD1881 
Syntaxin-18 (STX18) LDTP13086 72.50  LDD1881 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 17.15  LDD1881 
TBC1 domain family member 9B (TBC1D9B) LDTP15057 16.00  LDD1881 
Tetraspanin-6 (TSPAN6) LDTP14458 46.85  LDD1881 
TraB domain-containing protein (TRABD) LDTP19963 25.46  LDD1881 
Transcription initiation protein SPT3 homolog (SUPT3H) LDTP01236 16.34  LDD1881 
Transducin beta-like protein 2 (TBL2) LDTP16285 16.34  LDD1881 
Translocon-associated protein subunit delta (SSR4) LDTP04425 26.17  LDD1881 
Transmembrane protein 161A (TMEM161A) LDTP12762 15.45  LDD1881 
Trophoblast glycoprotein (TPBG) LDTP05960 15.24  LDD1881 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 59.71  LDD1881 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 22.32  LDD1881 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 15.45  LDD1881 
Vimentin (VIM) LDTP02297 16.91  LDD1881 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1881 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587