Details of the Probe

General Information of Probe

Probe ID
LDPC0541
Probe Name
C314
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 356.817
Lipid-water partition coefficient (xlogp) 2.9555
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C17H17ClN6O
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])N([H])C(=O)c2c([H])c(C3([H])C([H])([H])C3([H])[H])nc3c(Cl)c([H])nn23)N=N1
InChI
InChI=1S/C17H17ClN6O/c1-2-3-6-17(22-23-17)7-8-19-16(25)14-9-13(11-4-5-11)21-15-12(18)10-20-24(14)15/h1,9-11H,3-8H2,(H,19,25)
InChIKey
XQNRHZMDKOTYEK-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

123 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 62.68  LDD1981 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 32.67  LDD1981 
Abasic site processing protein HMCES (HMCES) LDTP10322 22.16  LDD1981 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 16.91  LDD1981 
Acid ceramidase (ASAH1) LDTP05905 44.02  LDD1981 
Adenosine deaminase (ADA) LDTP01803 86.82  LDD1981 
ADP-dependent glucokinase (ADPGK) LDTP11127 25.46  LDD1981 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 25.63  LDD1981 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 17.15  LDD1981 
Alpha-galactosidase A (GLA) LDTP02141 12.38  LDD1981 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 26.91  LDD1981 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 13.93  LDD1981 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 22.16  LDD1981 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 14.22  LDD1981 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 11.31  LDD1981 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 18.25  LDD1981 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 21.86  LDD1981 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.01  LDD1981 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 23.59  LDD1981 
Cartilage-associated protein (CRTAP) LDTP01300 11.63  LDD1981 
Cathepsin B (CTSB) LDTP02223 16.80  LDD1981 
Ceramide glucosyltransferase (UGCG) LDTP06617 49.87  LDD1981 
Ceramide synthase 1 (CERS1) LDTP03394 15.56  LDD1981 
Ceramide synthase 2 (CERS2) LDTP10329 13.93  LDD1981 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 11.96  LDD1981 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 19.16  LDD1981 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 21.26  LDD1981 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 58.49  LDD1981 
Cytochrome b5 type B (CYB5B) LDTP00697 15.56  LDD1981 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 39.95  LDD1981 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 13.27  LDD1981 
DCN1-like protein 4 (DCUN1D4) LDTP09799 42.22  LDD1981 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 21.26  LDD1981 
DNA-directed RNA polymerase III subunit RPC6 (POLR3F) LDTP11762 15.35  LDD1981 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 19.84  LDD1981 
Dual specificity protein phosphatase 12 (DUSP12) LDTP13663 13.74  LDD1981 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 12.47  LDD1981 
Elongation factor 1-alpha 2 (EEF1A2) LDTP05460 12.64  LDD1981 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 17.63  LDD1981 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 11.47  LDD1981 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 16.45  LDD1981 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 19.03  LDD1981 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 16.45  LDD1981 
Epoxide hydrolase 1 (EPHX1) LDTP02175 13.64  LDD1981 
Ethanolamine kinase 1 (ETNK1) LDTP12197 32.22  LDD1981 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 12.13  LDD1981 
Ferrochelatase, mitochondrial (FECH) LDTP03198 34.78  LDD1981 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 14.03  LDD1981 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 15.89  LDD1981 
Heme oxygenase 1 (HMOX1) LDTP02359 35.26  LDD1981 
Heme oxygenase 2 (HMOX2) LDTP03540 55.72  LDD1981 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 13.93  LDD1981 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 18.90  LDD1981 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 11.88  LDD1981 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 14.93  LDD1981 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 50.21  LDD1981 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.89  LDD1981 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 13.74  LDD1981 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 39.40  LDD1981 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 14.83  LDD1981 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 30.48  LDD1981 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 13.45  LDD1981 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 25.28  LDD1981 
Lysosomal acid phosphatase (ACP2) LDTP02539 11.39  LDD1981 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 17.75  LDD1981 
Lysosomal protective protein (CTSA) LDTP02505 17.27  LDD1981 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 28.84  LDD1981 
Macrophage migration inhibitory factor (MIF) LDTP02713 26.91  LDD1981 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1) LDTP03677 24.25  LDD1981 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 14.93  LDD1981 
Minor histocompatibility antigen H13 (HM13) LDTP09396 24.08  LDD1981 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 11.88  LDD1981 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 12.82  LDD1981 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 15.89  LDD1981 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 12.13  LDD1981 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 18.25  LDD1981 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 15.35  LDD1981 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 14.83  LDD1981 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 47.18  LDD1981 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 19.29  LDD1981 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 15.78  LDD1981 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 19.43  LDD1981 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 73.01  LDD1981 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 15.67  LDD1981 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 15.67  LDD1981 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 15.03  LDD1981 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 15.24  LDD1981 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 14.42  LDD1981 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 31.56  LDD1981 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 15.89  LDD1981 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 22.78  LDD1981 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 12.73  LDD1981 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 39.95  LDD1981 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 12.30  LDD1981 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 13.55  LDD1981 
Protein arginine N-methyltransferase 9 (PRMT9) LDTP07525 11.39  LDD1981 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 11.47  LDD1981 
Protein O-GlcNAcase (OGA) LDTP00988 12.82  LDD1981 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 17.03  LDD1981 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 15.78  LDD1981 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 25.28  LDD1981 
Ras-related protein Rab-24 (RAB24) LDTP10020 11.88  LDD1981 
Ras-related protein Rab-34 (RAB34) LDTP11535 13.45  LDD1981 
Ras-related protein Rab-5A (RAB5A) LDTP03050 11.47  LDD1981 
Ras-related protein Rab-5B (RAB5B) LDTP04893 13.27  LDD1981 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 45.57  LDD1981 
Ribitol 5-phosphate transferase FKRP (FKRP) LDTP12109 11.96  LDD1981 
Ribonuclease T2 (RNASET2) LDTP00316 13.27  LDD1981 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 14.03  LDD1981 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 11.96  LDD1981 
Serine protease HTRA2, mitochondrial (HTRA2) LDTP00773 13.55  LDD1981 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 24.93  LDD1981 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 13.45  LDD1981 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 19.84  LDD1981 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 11.71  LDD1981 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 12.91  LDD1981 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 21.71  LDD1981 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 15.24  LDD1981 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 20.82  LDD1981 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 26.72  LDD1981 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 11.47  LDD1981 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 64.89  LDD1981 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 14.32  LDD1981 
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⏷ Show the Full List of 123 Enzyme
88 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 25.99  LDD1981 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 16.91  LDD1981 
Amyloid-beta precursor protein (APP) LDTP02071 15.24  LDD1981 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 14.12  LDD1981 
ATP synthase subunit a (MT-ATP6) LDTP01804 50.56  LDD1981 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 43.41  LDD1981 
BRI3-binding protein (BRI3BP) LDTP15648 34.06  LDD1981 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 12.13  LDD1981 
Clathrin light chain A (CLTA) LDTP02352 11.24  LDD1981 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 13.27  LDD1981 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 14.52  LDD1981 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 16.80  LDD1981 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 13.27  LDD1981 
Derlin-1 (DERL1) LDTP11245 15.24  LDD1981 
Derlin-2 (DERL2) LDTP11634 12.30  LDD1981 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 11.39  LDD1981 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 70.52  LDD1981 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 18.38  LDD1981 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 11.71  LDD1981 
Guided entry of tail-anchored proteins factor CAMLG (CAMLG) LDTP04227 65.80  LDD1981 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 13.18  LDD1981 
Integral membrane protein 2B (ITM2B) LDTP13833 14.83  LDD1981 
Integral membrane protein 2C (ITM2C) LDTP12451 15.89  LDD1981 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 12.30  LDD1981 
Lysosome membrane protein 2 (SCARB2) LDTP06034 66.26  LDD1981 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 35.75  LDD1981 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 59.30  LDD1981 
Metaxin-1 (MTX1) LDTP05900 15.45  LDD1981 
Metaxin-3 (MTX3) LDTP14970 21.26  LDD1981 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 11.47  LDD1981 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 11.55  LDD1981 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 34.54  LDD1981 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 19.56  LDD1981 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 65.34  LDD1981 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 87.43  LDD1981 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 17.03  LDD1981 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 19.43  LDD1981 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 19.29  LDD1981 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 38.85  LDD1981 
Mpv17-like protein 2 (MPV17L2) LDTP14952 17.75  LDD1981 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 11.63  LDD1981 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 11.31  LDD1981 
Nucleoporin NDC1 (NDC1) LDTP11213 14.52  LDD1981 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 13.55  LDD1981 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 11.88  LDD1981 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 36.76  LDD1981 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 26.72  LDD1981 
Prosaposin (PSAP) LDTP02215 31.78  LDD1981 
Protein GPR107 (GPR107) LDTP07236 24.25  LDD1981 
Protein GPR108 (GPR108) LDTP12383 11.31  LDD1981 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 12.30  LDD1981 
Protein spinster homolog 1 (SPNS1) LDTP11844 15.56  LDD1981 
Protein tweety homolog 3 (TTYH3) LDTP11615 34.30  LDD1981 
Protein wntless homolog (WLS) LDTP07156 15.56  LDD1981 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 14.72  LDD1981 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 18.64  LDD1981 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 17.75  LDD1981 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 21.26  LDD1981 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 17.51  LDD1981 
Sideroflexin-4 (SFXN4) LDTP07531 22.47  LDD1981 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 26.17  LDD1981 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 13.18  LDD1981 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 13.64  LDD1981 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 38.85  LDD1981 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 16.68  LDD1981 
Sorting nexin-2 (SNX2) LDTP01043 14.83  LDD1981 
Sorting nexin-27 (SNX27) LDTP10533 15.78  LDD1981 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 29.24  LDD1981 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 29.24  LDD1981 
Stomatin (STOM) LDTP03380 11.88  LDD1981 
Surfeit locus protein 4 (SURF4) LDTP00592 35.75  LDD1981 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 18.90  LDD1981 
Syntaxin-6 (STX6) LDTP00857 27.47  LDD1981 
Tetraspanin-3 (TSPAN3) LDTP16813 57.68  LDD1981 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 26.35  LDD1981 
Translocator protein (TSPO) LDTP03546 18.38  LDD1981 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 40.50  LDD1981 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 15.67  LDD1981 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 22.78  LDD1981 
Transmembrane protein 126A (TMEM126A) LDTP15948 15.67  LDD1981 
Transmembrane protein 160 (TMEM160) LDTP20002 19.56  LDD1981 
Transmembrane protein 199 (TMEM199) LDTP08881 26.17  LDD1981 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 23.59  LDD1981 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 56.49  LDD1981 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 38.32  LDD1981 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 15.24  LDD1981 
WASH complex subunit 4 (WASHC4) LDTP06702 30.27  LDD1981 
Zinc transporter 7 (SLC30A7) LDTP09180 12.47  LDD1981 
------------------------------------------------------------------------------------
⏷ Show the Full List of 88 Transporter and channel
4 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 12.47  LDD1981 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 15.56  LDD1981 
G-protein coupled receptor-associated sorting protein 2 (GPRASP2) LDTP10195 12.21  LDD1981 
Y-box-binding protein 1 (YBX1) LDTP05065 13.18  LDD1981 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 15.35  LDD1981 
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105 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 12.13  LDD1981 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 15.45  LDD1981 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.78  LDD1981 
Apolipoprotein L2 (APOL2) LDTP11076 30.06  LDD1981 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 16.00  LDD1981 
BAG family molecular chaperone regulator 5 (BAG5) LDTP13507 15.67  LDD1981 
Bromodomain-containing protein 7 (BRD7) LDTP12369 13.09  LDD1981 
C-type mannose receptor 2 (MRC2) LDTP13114 11.24  LDD1981 
Calumenin (CALU) LDTP00887 12.21  LDD1981 
Centrin-2 (CETN2) LDTP03926 14.83  LDD1981 
Clustered mitochondria protein homolog (CLUH) LDTP14486 17.15  LDD1981 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 11.55  LDD1981 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 13.36  LDD1981 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 11.24  LDD1981 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 53.82  LDD1981 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 11.88  LDD1981 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 13.36  LDD1981 
Dymeclin (DYM) LDTP08000 17.51  LDD1981 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 29.24  LDD1981 
Emerin (EMD) LDTP04356 11.24  LDD1981 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 32.90  LDD1981 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1981 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 51.27  LDD1981 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 15.67  LDD1981 
F-box/WD repeat-containing protein 1A (BTRC) LDTP13838 11.39  LDD1981 
Ganglioside GM2 activator (GM2A) LDTP02927 15.78  LDD1981 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 12.82  LDD1981 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 12.73  LDD1981 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 20.97  LDD1981 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 11.63  LDD1981 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 11.31  LDD1981 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 12.64  LDD1981 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 11.16  LDD1981 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 12.91  LDD1981 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 11.16  LDD1981 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 14.52  LDD1981 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 16.68  LDD1981 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 17.63  LDD1981 
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) LDTP01246 12.38  LDD1981 
Kinesin light chain 2 (KLC2) LDTP11695 13.27  LDD1981 
Kinetochore protein Spc24 (SPC24) LDTP09069 12.38  LDD1981 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 29.24  LDD1981 
LYR motif-containing protein 2 (LYRM2) LDTP18467 14.22  LDD1981 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 11.79  LDD1981 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 11.63  LDD1981 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 27.86  LDD1981 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 53.08  LDD1981 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 13.55  LDD1981 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 14.83  LDD1981 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 12.47  LDD1981 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 75.06  LDD1981 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 41.07  LDD1981 
NCK-interacting protein with SH3 domain (NCKIPSD) LDTP12929 17.88  LDD1981 
Neudesin (NENF) LDTP13630 14.12  LDD1981 
Neurofilament light polypeptide (NEFL) LDTP02180 12.38  LDD1981 
Nucleobindin-2 (NUCB2) LDTP05160 48.17  LDD1981 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 11.71  LDD1981 
Optic atrophy 3 protein (OPA3) LDTP16006 12.73  LDD1981 
Periphilin-1 (PPHLN1) LDTP09183 14.72  LDD1981 
Plexin-B2 (PLXNB2) LDTP00513 11.88  LDD1981 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 18.90  LDD1981 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 11.63  LDD1981 
Prefoldin subunit 6 (PFDN6) LDTP00573 14.83  LDD1981 
Programmed cell death protein 5 (PDCD5) LDTP00417 16.91  LDD1981 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 12.30  LDD1981 
Protein CREG1 (CREG1) LDTP01279 33.36  LDD1981 
Protein ecdysoneless homolog (ECD) LDTP01711 14.22  LDD1981 
Protein FAM114A2 (FAM114A2) LDTP16080 20.53  LDD1981 
Protein FAM162A (FAM162A) LDTP10056 25.28  LDD1981 
Protein FAM177A1 (FAM177A1) LDTP15398 15.67  LDD1981 
Protein jagunal homolog 1 (JAGN1) LDTP08904 11.24  LDD1981 
Protein SERAC1 (SERAC1) LDTP10487 23.59  LDD1981 
Protein TASOR (TASOR) LDTP13430 14.83  LDD1981 
Protein YIF1A (YIF1A) LDTP01494 12.64  LDD1981 
RalBP1-associated Eps domain-containing protein 1 (REPS1) LDTP10203 13.83  LDD1981 
Reticulocalbin-2 (RCN2) LDTP06097 19.84  LDD1981 
Reticulon-2 (RTN2) LDTP01167 14.32  LDD1981 
Reticulon-3 (RTN3) LDTP01522 15.24  LDD1981 
Reticulon-4 (RTN4) LDTP12412 13.74  LDD1981 
RNA binding protein fox-1 homolog 2 (RBFOX2) LDTP00716 11.55  LDD1981 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 11.16  LDD1981 
RNA-binding protein 10 (RBM10) LDTP05224 20.53  LDD1981 
RNA-binding protein 3 (RBM3) LDTP05226 17.03  LDD1981 
RNA-binding protein 5 (RBM5) LDTP04527 17.63  LDD1981 
RNA-binding protein EWS (EWSR1) LDTP05318 12.73  LDD1981 
RNA-binding protein FUS (FUS) LDTP03775 15.78  LDD1981 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 19.43  LDD1981 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 15.14  LDD1981 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 12.04  LDD1981 
Splicing factor ESS-2 homolog (ESS2) LDTP10214 11.47  LDD1981 
Stathmin (STMN1) LDTP02869 11.63  LDD1981 
Superkiller complex protein 8 (SKIC8) LDTP11643 17.39  LDD1981 
Synaptogyrin-2 (SYNGR2) LDTP00859 14.42  LDD1981 
Syntaxin-10 (STX10) LDTP00986 13.00  LDD1981 
Syntaxin-18 (STX18) LDTP13086 20.39  LDD1981 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 14.42  LDD1981 
Tetraspanin-6 (TSPAN6) LDTP14458 45.57  LDD1981 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 16.34  LDD1981 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 15.89  LDD1981 
TraB domain-containing protein (TRABD) LDTP19963 14.72  LDD1981 
Tropomyosin alpha-1 chain (TPM1) LDTP02351 12.21  LDD1981 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 11.79  LDD1981 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 47.18  LDD1981 
Vimentin (VIM) LDTP02297 14.03  LDD1981 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 19.16  LDD1981 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1981 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587