Details of the Target

General Information of Target

Target ID LDTP00513
Target Name Plexin-B2 (PLXNB2)
Gene Name PLXNB2
Gene ID 23654
Synonyms
KIAA0315; Plexin-B2; MM1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAK
LQLEQQVATGPALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGIC
ALRALSNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNG
IIVSTRLLDRTDSREAFEAYTDHATYKAGYLSTNTQQFVAAFEDGPYVFFVFNQQDKHPA
RNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRD
SRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSK
SFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL
TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRD
SQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLT
VSPLPALSEEDELLCLFGESPPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRR
GNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECREASPNPEDGIVRA
HMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHVGSDLLKFMEPVTMQESGT
FAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLCRAANPDYRCA
WCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV
AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSV
EPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQML
LEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIA
EPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRA
LLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMK
TLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSL
ILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM
EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFS
NLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQY
VVAKNPKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAV
QKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYR
GQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSK
VGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEI
YLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK
TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLL
YAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQK
YYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL
Target Bioclass
Other
Family
Plexin family
Subcellular location
Cell membrane
Function
Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42.
Uniprot ID
O15031
Ensemble ID
ENST00000359337.9
HGNC ID
HGNC:9104

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 19 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
YN-1
 Probe Info  		100.00  LDD0444  [1]
STPyne
 Probe Info  		K1290(3.18); K1429(0.88); K1491(5.60); K1729(7.61)  LDD0277  [2]
ONAyne
 Probe Info  		K1429(5.56)  LDD0275  [2]
OPA-S-S-alkyne
 Probe Info  		K322(0.66); K1121(0.81); K1159(1.75); K941(2.31)  LDD3494  [3]
m-APA
 Probe Info  		11.86  LDD0403  [4]
BTD
 Probe Info  		C1484(0.81)  LDD2137  [5]
Acrolein
 Probe Info  		C666(0.00); C948(0.00)  LDD0222  [6]
DBIA
 Probe Info  		C779(0.91); C782(0.91); C767(0.85); C770(0.85)  LDD0078  [7]
5E-2FA
 Probe Info  		H272(0.00); H203(0.00); H177(0.00); H701(0.00)  LDD2235  [8]
IA-alkyne
 Probe Info  		C312(0.00); C615(0.00); C1484(0.00); C351(0.00)  LDD0162  [9]
WYneN
 Probe Info  		N.A.  LDD0021  [10]
WYneO
 Probe Info  		N.A.  LDD0022  [10]
IPM
 Probe Info  		N.A.  LDD0147  [11]
SF
 Probe Info  		N.A.  LDD0028  [12]
TFBX
 Probe Info  		C1484(0.00); C948(0.00); C770(0.00); C937(0.00)  LDD0148  [11]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [6]
Methacrolein
 Probe Info  		C948(0.00); C770(0.00); C112(0.00); C1484(0.00)  LDD0218  [6]
AOyne
 Probe Info  		15.00  LDD0443  [13]
NAIA_5
 Probe Info  		C351(0.00); C112(0.00); C330(0.00); C312(0.00)  LDD2223  [14]
PAL-AfBPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C106
 Probe Info  		19.70  LDD1793  [15]
C108
 Probe Info  		10.41  LDD1795  [15]
C271
 Probe Info  		9.65  LDD1941  [15]
C273
 Probe Info  		5.17  LDD1943  [15]
C310
 Probe Info  		19.70  LDD1977  [15]
C314
 Probe Info  		11.88  LDD1981  [15]
STS-2
 Probe Info  		N.A.  LDD0139  [16]
Alk-rapa
 Probe Info  		2.66  LDD0213  [17]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C615(1.12); C767(0.70); C770(0.90); C782(1.31)  LDD0531  [7]
 LDCM0215  AC10 HCT 116 C615(1.14); C767(0.76); C770(1.15); C782(0.94)  LDD0532  [7]
 LDCM0216  AC100 HCT 116 C1504(0.88); C330(1.39); C615(0.81); C767(1.07)  LDD0533  [7]
 LDCM0217  AC101 HCT 116 C1504(0.92); C330(1.25); C615(0.70); C767(1.14)  LDD0534  [7]
 LDCM0218  AC102 HCT 116 C1504(1.14); C330(1.55); C615(0.69); C767(0.99)  LDD0535  [7]
 LDCM0219  AC103 HCT 116 C1504(1.27); C330(1.32); C615(0.69); C767(1.49)  LDD0536  [7]
 LDCM0220  AC104 HCT 116 C1504(1.28); C330(1.14); C615(0.84); C767(1.02)  LDD0537  [7]
 LDCM0221  AC105 HCT 116 C1504(1.56); C330(1.26); C615(0.61); C767(1.14)  LDD0538  [7]
 LDCM0222  AC106 HCT 116 C1504(1.36); C330(1.75); C615(0.57); C767(1.45)  LDD0539  [7]
 LDCM0223  AC107 HCT 116 C1504(0.87); C330(1.33); C615(0.57); C767(1.22)  LDD0540  [7]
 LDCM0224  AC108 HCT 116 C1504(1.44); C330(1.56); C615(0.68); C767(1.17)  LDD0541  [7]
 LDCM0225  AC109 HCT 116 C1504(1.15); C330(1.53); C615(0.75); C767(0.83)  LDD0542  [7]
 LDCM0226  AC11 HCT 116 C615(1.06); C767(0.73); C770(1.23); C782(1.02)  LDD0543  [7]
 LDCM0227  AC110 HCT 116 C1504(0.99); C330(1.53); C615(0.75); C767(1.42)  LDD0544  [7]
 LDCM0228  AC111 HCT 116 C1504(1.16); C330(1.48); C615(0.67); C767(1.19)  LDD0545  [7]
 LDCM0229  AC112 HCT 116 C1504(0.97); C330(1.34); C615(0.62); C767(1.27)  LDD0546  [7]
 LDCM0230  AC113 HCT 116 C330(1.06); C615(1.14); C767(1.13); C782(0.92)  LDD0547  [7]
 LDCM0231  AC114 HCT 116 C330(1.05); C615(1.07); C767(1.30); C782(0.88)  LDD0548  [7]
 LDCM0232  AC115 HCT 116 C330(1.43); C615(0.99); C767(1.18); C782(0.96)  LDD0549  [7]
 LDCM0233  AC116 HCT 116 C330(1.12); C615(0.96); C767(0.94); C782(1.06)  LDD0550  [7]
 LDCM0234  AC117 HCT 116 C330(1.35); C615(1.07); C767(1.03); C782(1.05)  LDD0551  [7]
 LDCM0235  AC118 HCT 116 C330(2.70); C615(1.08); C767(1.17); C782(0.89)  LDD0552  [7]
 LDCM0236  AC119 HCT 116 C330(1.40); C615(1.07); C767(1.15); C782(0.90)  LDD0553  [7]
 LDCM0237  AC12 HCT 116 C615(1.05); C767(0.78); C770(0.86); C782(0.79)  LDD0554  [7]
 LDCM0238  AC120 HCT 116 C330(0.65); C615(1.18); C767(1.08); C782(0.90)  LDD0555  [7]
 LDCM0239  AC121 HCT 116 C330(1.43); C615(1.14); C767(0.96); C782(0.87)  LDD0556  [7]
 LDCM0240  AC122 HCT 116 C330(1.19); C615(1.03); C767(1.22); C782(0.84)  LDD0557  [7]
 LDCM0241  AC123 HCT 116 C330(1.63); C615(1.22); C767(0.99); C782(0.75)  LDD0558  [7]
 LDCM0242  AC124 HCT 116 C330(2.06); C615(1.18); C767(0.96); C782(0.92)  LDD0559  [7]
 LDCM0243  AC125 HCT 116 C330(1.34); C615(1.20); C767(1.17); C782(0.93)  LDD0560  [7]
 LDCM0244  AC126 HCT 116 C330(1.32); C615(1.08); C767(1.07); C782(0.95)  LDD0561  [7]
 LDCM0245  AC127 HCT 116 C330(1.87); C615(1.32); C767(1.08); C782(0.94)  LDD0562  [7]
 LDCM0246  AC128 HCT 116 C615(1.08); C770(0.82)  LDD0563  [7]
 LDCM0247  AC129 HCT 116 C615(1.57); C770(1.13)  LDD0564  [7]
 LDCM0249  AC130 HCT 116 C615(0.97); C770(1.04)  LDD0566  [7]
 LDCM0250  AC131 HCT 116 C615(1.59); C770(0.87)  LDD0567  [7]
 LDCM0251  AC132 HCT 116 C615(0.96); C770(1.09)  LDD0568  [7]
 LDCM0252  AC133 HCT 116 C615(0.95); C770(1.12)  LDD0569  [7]
 LDCM0253  AC134 HCT 116 C615(1.02); C770(1.23)  LDD0570  [7]
 LDCM0254  AC135 HCT 116 C615(0.95); C770(1.00)  LDD0571  [7]
 LDCM0255  AC136 HCT 116 C615(1.12); C770(1.15)  LDD0572  [7]
 LDCM0256  AC137 HCT 116 C615(1.23); C770(1.00)  LDD0573  [7]
 LDCM0257  AC138 HCT 116 C615(1.31); C770(1.04)  LDD0574  [7]
 LDCM0258  AC139 HCT 116 C615(1.16); C770(1.23)  LDD0575  [7]
 LDCM0259  AC14 HCT 116 C615(1.09); C767(0.76); C770(1.10); C782(0.99)  LDD0576  [7]
 LDCM0260  AC140 HCT 116 C615(0.98); C770(1.51)  LDD0577  [7]
 LDCM0261  AC141 HCT 116 C615(1.01); C770(1.43)  LDD0578  [7]
 LDCM0262  AC142 HCT 116 C615(1.10); C770(0.98)  LDD0579  [7]
 LDCM0263  AC143 HCT 116 C615(0.60); C767(0.80); C782(0.80); C1504(0.87)  LDD0580  [7]
 LDCM0264  AC144 HCT 116 C615(0.64); C1504(0.67); C782(0.89); C767(1.15)  LDD0581  [7]
 LDCM0265  AC145 HCT 116 C615(0.62); C1504(0.72); C782(0.77); C767(0.94)  LDD0582  [7]
 LDCM0266  AC146 HCT 116 C1504(0.60); C782(0.72); C615(0.77); C767(0.96)  LDD0583  [7]
 LDCM0267  AC147 HCT 116 C1504(0.73); C767(0.81); C782(0.85); C615(1.01)  LDD0584  [7]
 LDCM0268  AC148 HCT 116 C1504(0.45); C782(0.68); C615(0.91); C767(0.91)  LDD0585  [7]
 LDCM0269  AC149 HCT 116 C615(0.56); C782(0.57); C1504(0.71); C767(0.72)  LDD0586  [7]
 LDCM0270  AC15 HCT 116 C767(0.76); C770(0.98); C782(0.98); C615(1.13)  LDD0587  [7]
 LDCM0271  AC150 HCT 116 C782(0.68); C615(0.71); C1504(0.79); C767(0.99)  LDD0588  [7]
 LDCM0272  AC151 HCT 116 C782(0.58); C1504(0.76); C615(0.83); C767(0.99)  LDD0589  [7]
 LDCM0273  AC152 HCT 116 C1504(0.58); C782(0.68); C767(0.83); C615(1.09)  LDD0590  [7]
 LDCM0274  AC153 HCT 116 C1504(0.47); C615(0.59); C782(0.71); C767(0.73)  LDD0591  [7]
 LDCM0621  AC154 HCT 116 C1504(0.56); C615(0.85); C767(0.82); C782(0.72)  LDD2158  [7]
 LDCM0622  AC155 HCT 116 C1504(0.82); C615(1.00); C767(0.80); C782(0.62)  LDD2159  [7]
 LDCM0623  AC156 HCT 116 C1504(1.09); C615(0.80); C767(0.94); C782(0.87)  LDD2160  [7]
 LDCM0624  AC157 HCT 116 C1504(0.74); C615(0.75); C767(0.68); C782(0.81)  LDD2161  [7]
 LDCM0276  AC17 HCT 116 C767(0.87); C782(0.87); C615(1.11); C1504(1.21)  LDD0593  [7]
 LDCM0277  AC18 HCT 116 C1504(0.63); C782(0.83); C615(0.86); C767(0.93)  LDD0594  [7]
 LDCM0278  AC19 HCT 116 C330(0.79); C782(0.97); C767(0.99); C1504(1.00)  LDD0595  [7]
 LDCM0279  AC2 HCT 116 C615(0.97); C767(1.00); C770(1.06); C782(1.64)  LDD0596  [7]
 LDCM0280  AC20 HCT 116 C782(0.70); C615(0.86); C1504(0.87); C767(0.96)  LDD0597  [7]
 LDCM0281  AC21 HCT 116 C782(0.72); C615(0.91); C767(0.95); C1504(1.00)  LDD0598  [7]
 LDCM0282  AC22 HCT 116 C1504(0.80); C782(0.85); C330(0.85); C767(1.09)  LDD0599  [7]
 LDCM0283  AC23 HCT 116 C782(0.79); C767(0.94); C1504(0.96); C615(1.01)  LDD0600  [7]
 LDCM0284  AC24 HCT 116 C330(0.77); C782(0.97); C767(1.04); C615(1.11)  LDD0601  [7]
 LDCM0285  AC25 HCT 116 C767(0.79); C770(1.12)  LDD0602  [7]
 LDCM0286  AC26 HCT 116 C767(0.96); C770(1.26)  LDD0603  [7]
 LDCM0287  AC27 HCT 116 C767(0.89); C770(1.11)  LDD0604  [7]
 LDCM0288  AC28 HCT 116 C770(1.00); C767(1.00)  LDD0605  [7]
 LDCM0289  AC29 HCT 116 C770(1.12); C767(1.15)  LDD0606  [7]
 LDCM0290  AC3 HCT 116 C615(0.91); C767(0.93); C770(1.02); C782(1.16)  LDD0607  [7]
 LDCM0291  AC30 HCT 116 C770(1.23); C767(1.28)  LDD0608  [7]
 LDCM0292  AC31 HCT 116 C770(0.87); C767(0.97)  LDD0609  [7]
 LDCM0293  AC32 HCT 116 C770(0.88); C767(1.05)  LDD0610  [7]
 LDCM0294  AC33 HCT 116 C770(0.87); C767(1.01)  LDD0611  [7]
 LDCM0295  AC34 HCT 116 C767(0.93); C770(1.15)  LDD0612  [7]
 LDCM0296  AC35 HCT 116 C330(1.06); C767(1.10)  LDD0613  [7]
 LDCM0297  AC36 HCT 116 C330(0.98); C767(1.04)  LDD0614  [7]
 LDCM0298  AC37 HCT 116 C330(0.73); C767(0.85)  LDD0615  [7]
 LDCM0299  AC38 HCT 116 C330(0.89); C767(1.20)  LDD0616  [7]
 LDCM0300  AC39 HCT 116 C767(0.93); C330(1.08)  LDD0617  [7]
 LDCM0301  AC4 HCT 116 C767(0.63); C782(1.09); C770(1.12); C615(1.18)  LDD0618  [7]
 LDCM0302  AC40 HCT 116 C330(0.89); C767(1.06)  LDD0619  [7]
 LDCM0303  AC41 HCT 116 C767(0.94); C330(1.35)  LDD0620  [7]
 LDCM0304  AC42 HCT 116 C330(1.11); C767(1.14)  LDD0621  [7]
 LDCM0305  AC43 HCT 116 C330(0.78); C767(1.41)  LDD0622  [7]
 LDCM0306  AC44 HCT 116 C330(0.59); C767(0.88)  LDD0623  [7]
 LDCM0307  AC45 HCT 116 C330(1.03); C767(1.06)  LDD0624  [7]
 LDCM0308  AC46 HCT 116 C782(0.96); C615(1.01); C767(1.49); C330(1.78)  LDD0625  [7]
 LDCM0309  AC47 HCT 116 C782(0.94); C767(1.04); C615(1.05); C330(1.41)  LDD0626  [7]
 LDCM0310  AC48 HCT 116 C782(0.96); C615(1.10); C767(1.22); C330(1.80)  LDD0627  [7]
 LDCM0311  AC49 HCT 116 C615(0.93); C767(0.98); C782(1.19); C330(1.69)  LDD0628  [7]
 LDCM0312  AC5 HCT 116 C767(0.70); C770(1.16); C782(1.22); C615(1.27)  LDD0629  [7]
 LDCM0313  AC50 HCT 116 C782(0.93); C767(1.12); C615(1.22); C330(2.05)  LDD0630  [7]
 LDCM0314  AC51 HCT 116 C782(0.69); C767(0.95); C615(0.98); C330(2.07)  LDD0631  [7]
 LDCM0315  AC52 HCT 116 C782(0.72); C767(0.92); C615(1.00); C330(3.54)  LDD0632  [7]
 LDCM0316  AC53 HCT 116 C782(0.68); C767(0.96); C615(1.08); C330(1.73)  LDD0633  [7]
 LDCM0317  AC54 HCT 116 C782(0.79); C615(1.01); C767(1.12); C330(2.00)  LDD0634  [7]
 LDCM0318  AC55 HCT 116 C782(0.76); C767(0.83); C615(1.10); C330(2.09)  LDD0635  [7]
 LDCM0319  AC56 HCT 116 C782(0.61); C615(0.96); C767(1.00); C330(3.03)  LDD0636  [7]
 LDCM0320  AC57 HCT 116 C782(0.79); C615(0.97); C767(1.47); C770(1.91)  LDD0637  [7]
 LDCM0321  AC58 HCT 116 C782(0.85); C615(0.92); C767(1.11); C770(1.40)  LDD0638  [7]
 LDCM0322  AC59 HCT 116 C615(0.90); C782(1.12); C770(1.27); C767(1.29)  LDD0639  [7]
 LDCM0323  AC6 HCT 116 C767(0.80); C782(0.87); C615(1.24); C770(1.27)  LDD0640  [7]
 LDCM0324  AC60 HCT 116 C615(0.93); C782(1.04); C767(1.26); C770(1.35)  LDD0641  [7]
 LDCM0325  AC61 HCT 116 C782(0.88); C615(1.10); C767(1.18); C770(1.36)  LDD0642  [7]
 LDCM0326  AC62 HCT 116 C770(0.88); C782(1.04); C615(1.06); C767(1.14)  LDD0643  [7]
 LDCM0327  AC63 HCT 116 C782(0.94); C767(1.35); C615(1.39); C770(1.44)  LDD0644  [7]
 LDCM0328  AC64 HCT 116 C615(0.94); C782(0.98); C767(1.27); C770(1.36)  LDD0645  [7]
 LDCM0329  AC65 HCT 116 C770(0.70); C615(0.71); C767(1.04); C782(1.07)  LDD0646  [7]
 LDCM0330  AC66 HCT 116 C615(0.90); C767(0.95); C770(0.96); C782(0.98)  LDD0647  [7]
 LDCM0331  AC67 HCT 116 C615(0.65); C770(0.67); C767(0.93); C782(1.01)  LDD0648  [7]
 LDCM0332  AC68 HCT 116 C330(0.74); C782(0.83); C767(0.91); C615(0.94)  LDD0649  [7]
 LDCM0333  AC69 HCT 116 C782(0.77); C330(0.94); C615(0.96); C770(1.03)  LDD0650  [7]
 LDCM0334  AC7 HCT 116 C782(0.81); C767(0.97); C770(1.03); C615(1.18)  LDD0651  [7]
 LDCM0335  AC70 HCT 116 C615(0.93); C767(0.97); C770(0.98); C782(1.00)  LDD0652  [7]
 LDCM0336  AC71 HCT 116 C782(0.60); C330(0.76); C767(0.88); C615(0.94)  LDD0653  [7]
 LDCM0337  AC72 HCT 116 C782(0.71); C330(0.84); C770(0.91); C767(0.93)  LDD0654  [7]
 LDCM0338  AC73 HCT 116 C782(0.83); C615(0.85); C770(1.02); C767(1.06)  LDD0655  [7]
 LDCM0339  AC74 HCT 116 C330(0.74); C782(0.90); C767(0.90); C770(0.98)  LDD0656  [7]
 LDCM0340  AC75 HCT 116 C782(0.74); C330(0.84); C615(0.96); C770(0.98)  LDD0657  [7]
 LDCM0341  AC76 HCT 116 C782(0.76); C330(0.87); C767(0.96); C615(1.04)  LDD0658  [7]
 LDCM0342  AC77 HCT 116 C782(0.76); C330(0.80); C767(0.91); C615(0.92)  LDD0659  [7]
 LDCM0343  AC78 HCT 116 C782(0.81); C330(0.84); C615(0.99); C767(1.00)  LDD0660  [7]
 LDCM0344  AC79 HCT 116 C782(0.90); C615(0.90); C770(0.97); C767(1.01)  LDD0661  [7]
 LDCM0345  AC8 HCT 116 C782(0.80); C767(0.89); C770(1.07); C615(1.07)  LDD0662  [7]
 LDCM0346  AC80 HCT 116 C782(0.58); C330(0.81); C767(0.89); C615(0.92)  LDD0663  [7]
 LDCM0347  AC81 HCT 116 C782(0.80); C615(0.92); C330(0.94); C767(1.01)  LDD0664  [7]
 LDCM0348  AC82 HCT 116 C782(0.69); C330(0.72); C615(0.74); C770(0.79)  LDD0665  [7]
 LDCM0349  AC83 HCT 116 C615(0.96); C330(1.03); C782(1.21); C767(1.82)  LDD0666  [7]
 LDCM0350  AC84 HCT 116 C330(0.60); C615(1.07); C767(1.36); C770(1.36)  LDD0667  [7]
 LDCM0351  AC85 HCT 116 C330(0.82); C615(1.07); C782(1.36); C767(1.43)  LDD0668  [7]
 LDCM0352  AC86 HCT 116 C330(0.97); C782(1.09); C615(1.10); C767(1.36)  LDD0669  [7]
 LDCM0353  AC87 HCT 116 C615(0.93); C767(1.20); C770(1.20); C782(1.25)  LDD0670  [7]
 LDCM0354  AC88 HCT 116 C330(0.75); C615(0.84); C782(1.23); C767(1.50)  LDD0671  [7]
 LDCM0355  AC89 HCT 116 C330(0.78); C615(0.89); C782(1.22); C767(1.71)  LDD0672  [7]
 LDCM0357  AC90 HCT 116 C615(0.92); C330(1.02); C767(1.18); C770(1.18)  LDD0674  [7]
 LDCM0358  AC91 HCT 116 C330(0.91); C782(1.11); C615(1.15); C767(1.49)  LDD0675  [7]
 LDCM0359  AC92 HCT 116 C615(1.08); C782(1.24); C330(1.46); C767(1.75)  LDD0676  [7]
 LDCM0360  AC93 HCT 116 C330(0.89); C615(0.97); C782(1.08); C767(1.29)  LDD0677  [7]
 LDCM0361  AC94 HCT 116 C330(0.87); C615(1.04); C782(1.07); C767(1.18)  LDD0678  [7]
 LDCM0362  AC95 HCT 116 C615(0.95); C782(1.19); C767(1.53); C770(1.53)  LDD0679  [7]
 LDCM0363  AC96 HCT 116 C615(1.05); C782(1.07); C330(1.09); C767(1.70)  LDD0680  [7]
 LDCM0364  AC97 HCT 116 C330(0.82); C615(1.10); C782(1.32); C767(1.41)  LDD0681  [7]
 LDCM0365  AC98 HCT 116 C615(0.37); C330(0.79); C767(1.24); C1504(1.43)  LDD0682  [7]
 LDCM0366  AC99 HCT 116 C615(0.64); C1504(0.99); C767(1.06); C330(1.31)  LDD0683  [7]
 LDCM0248  AKOS034007472 HCT 116 C615(1.08); C767(0.86); C770(1.01); C782(0.90)  LDD0565  [7]
 LDCM0356  AKOS034007680 HCT 116 C767(0.80); C615(1.10); C770(1.18); C782(1.27)  LDD0673  [7]
 LDCM0275  AKOS034007705 HCT 116 C767(0.78); C782(1.15); C615(1.25); C770(1.49)  LDD0592  [7]
 LDCM0156  Aniline NCI-H1299 11.86  LDD0403  [4]
 LDCM0020  ARS-1620 HCC44 C779(0.91); C782(0.91); C767(0.85); C770(0.85)  LDD0078  [7]
 LDCM0108  Chloroacetamide HeLa C666(0.00); C948(0.00)  LDD0222  [6]
 LDCM0367  CL1 HCT 116 C782(0.95); C767(1.27)  LDD0684  [7]
 LDCM0368  CL10 HCT 116 C782(1.17); C767(1.36)  LDD0685  [7]
 LDCM0369  CL100 HCT 116 C767(0.69); C782(0.88); C615(0.97); C770(1.11)  LDD0686  [7]
 LDCM0370  CL101 HCT 116 C767(0.81); C782(1.07); C615(1.12); C770(1.14)  LDD0687  [7]
 LDCM0371  CL102 HCT 116 C767(0.75); C782(0.88); C770(0.97); C615(1.44)  LDD0688  [7]
 LDCM0372  CL103 HCT 116 C767(0.77); C782(0.92); C770(1.01); C615(1.30)  LDD0689  [7]
 LDCM0373  CL104 HCT 116 C767(0.69); C782(0.91); C770(1.06); C615(1.31)  LDD0690  [7]
 LDCM0374  CL105 HCT 116 C1504(0.81); C782(0.91); C767(0.95); C615(0.99)  LDD0691  [7]
 LDCM0375  CL106 HCT 116 C767(0.70); C1504(0.74); C782(0.94); C615(1.05)  LDD0692  [7]
 LDCM0376  CL107 HCT 116 C767(0.77); C330(0.87); C1504(0.96); C615(1.01)  LDD0693  [7]
 LDCM0377  CL108 HCT 116 C330(0.69); C767(0.79); C1504(0.80); C782(0.96)  LDD0694  [7]
 LDCM0378  CL109 HCT 116 C1504(0.81); C767(0.94); C782(0.98); C615(1.14)  LDD0695  [7]
 LDCM0379  CL11 HCT 116 C782(0.87); C767(1.05)  LDD0696  [7]
 LDCM0380  CL110 HCT 116 C782(0.75); C1504(0.87); C330(0.96); C767(0.98)  LDD0697  [7]
 LDCM0381  CL111 HCT 116 C1504(0.87); C782(0.94); C330(1.02); C615(1.23)  LDD0698  [7]
 LDCM0382  CL112 HCT 116 C767(0.70); C770(0.82)  LDD0699  [7]
 LDCM0383  CL113 HCT 116 C770(0.82); C767(0.94)  LDD0700  [7]
 LDCM0384  CL114 HCT 116 C770(0.77); C767(0.94)  LDD0701  [7]
 LDCM0385  CL115 HCT 116 C770(0.81); C767(1.06)  LDD0702  [7]
 LDCM0386  CL116 HCT 116 C767(0.84); C770(1.16)  LDD0703  [7]
 LDCM0387  CL117 HCT 116 C330(0.80); C767(1.08)  LDD0704  [7]
 LDCM0388  CL118 HCT 116 C330(1.30); C767(1.32)  LDD0705  [7]
 LDCM0389  CL119 HCT 116 C767(1.20); C330(1.24)  LDD0706  [7]
 LDCM0390  CL12 HCT 116 C782(1.02); C767(1.35)  LDD0707  [7]
 LDCM0391  CL120 HCT 116 C767(1.17); C330(1.19)  LDD0708  [7]
 LDCM0392  CL121 HCT 116 C767(0.98); C615(1.00); C782(1.10); C330(1.75)  LDD0709  [7]
 LDCM0393  CL122 HCT 116 C782(0.73); C615(0.95); C767(1.26); C330(1.51)  LDD0710  [7]
 LDCM0394  CL123 HCT 116 C782(0.65); C767(0.85); C615(0.97); C330(2.32)  LDD0711  [7]
 LDCM0395  CL124 HCT 116 C782(0.66); C615(1.01); C767(1.04); C330(1.70)  LDD0712  [7]
 LDCM0396  CL125 HCT 116 C615(0.86); C770(1.03); C782(1.05); C767(1.14)  LDD0713  [7]
 LDCM0397  CL126 HCT 116 C782(0.70); C615(0.74); C767(2.39); C770(3.48)  LDD0714  [7]
 LDCM0398  CL127 HCT 116 C782(0.91); C615(1.00); C767(1.33); C770(1.36)  LDD0715  [7]
 LDCM0399  CL128 HCT 116 C615(0.71); C782(0.96); C767(1.33); C770(1.65)  LDD0716  [7]
 LDCM0400  CL13 HCT 116 C782(1.01); C767(1.09)  LDD0717  [7]
 LDCM0401  CL14 HCT 116 C782(1.09); C767(1.12)  LDD0718  [7]
 LDCM0402  CL15 HCT 116 C782(0.82); C767(0.85)  LDD0719  [7]
 LDCM0403  CL16 HCT 116 C767(1.14); C615(1.26)  LDD0720  [7]
 LDCM0404  CL17 HCT 116 C767(1.06); C615(1.30)  LDD0721  [7]
 LDCM0405  CL18 HCT 116 C767(1.29); C615(1.70)  LDD0722  [7]
 LDCM0406  CL19 HCT 116 C767(1.02); C615(1.11)  LDD0723  [7]
 LDCM0407  CL2 HCT 116 C782(0.93); C767(1.04)  LDD0724  [7]
 LDCM0408  CL20 HCT 116 C615(1.10); C767(1.29)  LDD0725  [7]
 LDCM0409  CL21 HCT 116 C767(0.99); C615(1.19)  LDD0726  [7]
 LDCM0410  CL22 HCT 116 C615(0.93); C767(1.18)  LDD0727  [7]
 LDCM0411  CL23 HCT 116 C767(1.00); C615(1.12)  LDD0728  [7]
 LDCM0412  CL24 HCT 116 C615(1.07); C767(1.76)  LDD0729  [7]
 LDCM0413  CL25 HCT 116 C615(0.97); C767(1.31)  LDD0730  [7]
 LDCM0414  CL26 HCT 116 C615(1.21); C767(1.16)  LDD0731  [7]
 LDCM0415  CL27 HCT 116 C615(1.02); C767(1.38)  LDD0732  [7]
 LDCM0416  CL28 HCT 116 C615(1.20); C767(1.10)  LDD0733  [7]
 LDCM0417  CL29 HCT 116 C615(0.99); C767(1.54)  LDD0734  [7]
 LDCM0418  CL3 HCT 116 C767(1.00); C782(0.85)  LDD0735  [7]
 LDCM0419  CL30 HCT 116 C615(1.04); C767(1.42)  LDD0736  [7]
 LDCM0420  CL31 HCT 116 C767(1.23)  LDD0737  [7]
 LDCM0421  CL32 HCT 116 C767(0.96)  LDD0738  [7]
 LDCM0422  CL33 HCT 116 C767(0.73)  LDD0739  [7]
 LDCM0423  CL34 HCT 116 C767(0.79)  LDD0740  [7]
 LDCM0424  CL35 HCT 116 C767(1.20)  LDD0741  [7]
 LDCM0425  CL36 HCT 116 C767(0.63)  LDD0742  [7]
 LDCM0426  CL37 HCT 116 C767(1.03)  LDD0743  [7]
 LDCM0428  CL39 HCT 116 C767(1.07)  LDD0745  [7]
 LDCM0429  CL4 HCT 116 C767(0.98); C782(0.89)  LDD0746  [7]
 LDCM0430  CL40 HCT 116 C767(0.93)  LDD0747  [7]
 LDCM0431  CL41 HCT 116 C767(1.08)  LDD0748  [7]
 LDCM0432  CL42 HCT 116 C767(0.86)  LDD0749  [7]
 LDCM0433  CL43 HCT 116 C767(1.13)  LDD0750  [7]
 LDCM0434  CL44 HCT 116 C767(1.12)  LDD0751  [7]
 LDCM0435  CL45 HCT 116 C767(1.11)  LDD0752  [7]
 LDCM0436  CL46 HCT 116 C615(1.28); C782(1.00)  LDD0753  [7]
 LDCM0437  CL47 HCT 116 C615(1.16); C782(0.85)  LDD0754  [7]
 LDCM0438  CL48 HCT 116 C615(0.97); C782(0.82)  LDD0755  [7]
 LDCM0439  CL49 HCT 116 C615(1.56); C782(0.84)  LDD0756  [7]
 LDCM0440  CL5 HCT 116 C767(1.23); C782(0.84)  LDD0757  [7]
 LDCM0441  CL50 HCT 116 C615(1.08); C782(0.84)  LDD0758  [7]
 LDCM0442  CL51 HCT 116 C615(0.96); C782(0.87)  LDD0759  [7]
 LDCM0443  CL52 HCT 116 C615(0.97); C782(1.09)  LDD0760  [7]
 LDCM0444  CL53 HCT 116 C615(1.07); C782(0.79)  LDD0761  [7]
 LDCM0445  CL54 HCT 116 C615(1.11); C782(0.87)  LDD0762  [7]
 LDCM0446  CL55 HCT 116 C615(1.40); C782(0.86)  LDD0763  [7]
 LDCM0447  CL56 HCT 116 C615(1.26); C782(0.85)  LDD0764  [7]
 LDCM0448  CL57 HCT 116 C615(0.85); C782(0.74)  LDD0765  [7]
 LDCM0449  CL58 HCT 116 C615(1.08); C782(0.95)  LDD0766  [7]
 LDCM0450  CL59 HCT 116 C615(1.12); C782(0.96)  LDD0767  [7]
 LDCM0451  CL6 HCT 116 C767(1.07); C782(0.88)  LDD0768  [7]
 LDCM0452  CL60 HCT 116 C615(1.31); C782(0.92)  LDD0769  [7]
 LDCM0453  CL61 HCT 116 C1504(0.69); C615(1.04); C767(1.31); C770(1.20)  LDD0770  [7]
 LDCM0454  CL62 HCT 116 C1504(0.70); C615(0.84); C767(1.49); C770(1.23)  LDD0771  [7]
 LDCM0455  CL63 HCT 116 C1504(0.67); C615(0.85); C767(2.10); C770(1.60)  LDD0772  [7]
 LDCM0456  CL64 HCT 116 C1504(0.67); C615(1.05); C767(2.36); C770(1.75)  LDD0773  [7]
 LDCM0457  CL65 HCT 116 C1504(0.57); C615(0.98); C767(1.71); C770(1.32)  LDD0774  [7]
 LDCM0458  CL66 HCT 116 C1504(0.89); C615(0.96); C767(1.71); C770(1.33)  LDD0775  [7]
 LDCM0459  CL67 HCT 116 C1504(0.80); C615(0.98); C767(2.15); C770(1.56)  LDD0776  [7]
 LDCM0460  CL68 HCT 116 C1504(0.64); C615(0.87); C767(1.98); C770(1.35)  LDD0777  [7]
 LDCM0461  CL69 HCT 116 C1504(0.87); C615(1.53); C767(1.77); C770(1.43)  LDD0778  [7]
 LDCM0462  CL7 HCT 116 C767(1.34); C782(1.06)  LDD0779  [7]
 LDCM0463  CL70 HCT 116 C1504(0.96); C615(1.03); C767(1.47); C770(1.17)  LDD0780  [7]
 LDCM0464  CL71 HCT 116 C1504(0.60); C615(0.84); C767(1.45); C770(1.20)  LDD0781  [7]
 LDCM0465  CL72 HCT 116 C1504(0.58); C615(0.74); C767(1.40); C770(1.31)  LDD0782  [7]
 LDCM0466  CL73 HCT 116 C1504(0.83); C615(0.91); C767(1.75); C770(1.32)  LDD0783  [7]
 LDCM0467  CL74 HCT 116 C1504(0.65); C615(0.92); C767(1.34); C770(1.15)  LDD0784  [7]
 LDCM0469  CL76 HCT 116 C767(1.04); C770(1.23)  LDD0786  [7]
 LDCM0470  CL77 HCT 116 C767(0.94); C770(0.96)  LDD0787  [7]
 LDCM0471  CL78 HCT 116 C767(1.09); C770(0.99)  LDD0788  [7]
 LDCM0472  CL79 HCT 116 C767(1.45); C770(1.32)  LDD0789  [7]
 LDCM0473  CL8 HCT 116 C767(1.01); C782(0.80)  LDD0790  [7]
 LDCM0474  CL80 HCT 116 C767(1.12); C770(1.33)  LDD0791  [7]
 LDCM0475  CL81 HCT 116 C767(1.22); C770(1.27)  LDD0792  [7]
 LDCM0476  CL82 HCT 116 C767(1.48); C770(1.17)  LDD0793  [7]
 LDCM0477  CL83 HCT 116 C767(1.19); C770(1.49)  LDD0794  [7]
 LDCM0478  CL84 HCT 116 C767(1.43); C770(1.39)  LDD0795  [7]
 LDCM0479  CL85 HCT 116 C767(1.11); C770(1.23)  LDD0796  [7]
 LDCM0480  CL86 HCT 116 C767(1.02); C770(0.92)  LDD0797  [7]
 LDCM0481  CL87 HCT 116 C767(1.11); C770(1.09)  LDD0798  [7]
 LDCM0482  CL88 HCT 116 C767(1.11); C770(1.13)  LDD0799  [7]
 LDCM0483  CL89 HCT 116 C767(1.56); C770(1.71)  LDD0800  [7]
 LDCM0484  CL9 HCT 116 C767(1.16); C782(0.80)  LDD0801  [7]
 LDCM0485  CL90 HCT 116 C767(1.01); C770(0.91)  LDD0802  [7]
 LDCM0486  CL91 HCT 116 C615(1.03); C767(0.98); C770(0.76); C782(0.77)  LDD0803  [7]
 LDCM0487  CL92 HCT 116 C615(1.06); C767(0.93); C770(0.89); C782(0.72)  LDD0804  [7]
 LDCM0488  CL93 HCT 116 C615(1.07); C767(0.89); C770(0.88); C782(0.92)  LDD0805  [7]
 LDCM0489  CL94 HCT 116 C615(1.16); C767(0.80); C770(0.95); C782(1.13)  LDD0806  [7]
 LDCM0490  CL95 HCT 116 C615(0.98); C767(0.89); C770(0.80); C782(0.79)  LDD0807  [7]
 LDCM0491  CL96 HCT 116 C615(1.08); C767(0.89); C770(0.87); C782(0.96)  LDD0808  [7]
 LDCM0492  CL97 HCT 116 C615(1.07); C767(0.92); C770(1.11); C782(1.08)  LDD0809  [7]
 LDCM0493  CL98 HCT 116 C615(0.97); C767(0.78); C770(0.84); C782(1.00)  LDD0810  [7]
 LDCM0494  CL99 HCT 116 C615(1.24); C767(0.82); C770(1.06); C782(0.88)  LDD0811  [7]
 LDCM0495  E2913 HEK-293T C1484(0.94); C637(1.00); C112(0.88); C1408(0.96)  LDD1698  [18]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C782(1.28)  LDD1702  [5]
 LDCM0468  Fragment33 HCT 116 C1504(0.89); C615(0.88); C767(1.51); C770(1.23)  LDD0785  [7]
 LDCM0427  Fragment51 HCT 116 C767(0.79)  LDD0744  [7]
 LDCM0022  KB02 HCT 116 C779(1.86); C782(1.77)  LDD0080  [7]
 LDCM0023  KB03 HCT 116 C779(1.83); C782(1.36)  LDD0081  [7]
 LDCM0024  KB05 HCT 116 C779(1.30); C782(1.27)  LDD0082  [7]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C1484(0.81)  LDD2137  [5]
 LDCM0090  Rapamycin JHH-7 2.66  LDD0213  [17]
 LDCM0021  THZ1 HCT 116 C779(1.32); C782(1.32); C767(1.40); C770(1.40)  LDD2173  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hepatocyte growth factor receptor (MET) Tyr protein kinase family P08581
Macrophage-stimulating protein receptor (MST1R) Tyr protein kinase family Q04912
Rho-related GTP-binding protein Rho6 (RND1) Rho family Q92730
Rho-related GTP-binding protein RhoE (RND3) Rho family P61587
Rho-related GTP-binding protein RhoN (RND2) Rho family P52198

References

1 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
4 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
7 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
8 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
9 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD029255
12 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
13 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
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Mass spectrometry data entry: PXD041264
15 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
16 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
17 Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth. Cell Chem Biol. 2022 Mar 17;29(3):373-385.e6. doi: 10.1016/j.chembiol.2021.10.006. Epub 2021 Oct 26.
18 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402