Probe Name	IA-alkyne					Probe Info
Probe concentration	100 uM
Criteria	Quantification: Probe vs (Probe+Competitor)
Quantitative Method	TMT
Competitor Name	BPK-21					Competitor Info
Competitor Concentration	20 uM
In Vivo Experiment Model	Model Type			Cell lysate
	Derived Tissue			Peripheral blood
	Disease Model		Normal
	Model Name		Human normal cell lysate (T cell)

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP13219	GTPase IMAP family member 2 (GIMAP2)				C261	20.0
LDTP12040	Prostaglandin E synthase 2 (PTGES2)				C110	15.2
LDTP03540	Heme oxygenase 2 (HMOX2)				C282	10.9
LDTP04358	Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)				C96	10.6
LDTP11127	ADP-dependent glucokinase (ADPGK)				C40	9.7
LDTP06787	Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1)				C265	9.0
LDTP10874	Platelet-activating factor acetylhydrolase 2, cytoplasmic (PAFAH2)				C72	8.3
LDTP03000	General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3)				C342	8.0
LDTP00577	Dihydroxyacetone phosphate acyltransferase (GNPAT)				C54	7.0
LDTP05845	cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (PDE3B)				C55	4.7

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP11873	Thioredoxin-interacting protein (TXNIP)				C170	14.4
LDTP00541	NPC intracellular cholesterol transporter 1 (NPC1)				C816	6.2
LDTP04071	Voltage-dependent anion-selective channel protein 2 (VDAC2)				C210, C227	5.3
LDTP08344	Stimulator of interferon genes protein (STING1)				C88, C91	4.3
LDTP12548	Phospholipid scramblase 3 (PLSCR3)				C125, C126	4.2

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP05257	Receptor expression-enhancing protein 5 (REEP5)				C18	20.0
LDTP12412	Reticulon-4 (RTN4)				C1101	9.8

1	An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.