Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | IPM | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 10 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
LFQ
|
|||||
| Competitor Name | GA | Competitor Info | ||||
| Competitor Concentration | 3 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Cell lysate | |||
| Derived Tissue |
|
Breast | ||||
| Disease Model | Invasive breast carcinoma [ICD-11:2C60] | |||||
| Model Name | Human invasive breast carcinoma cell lysate (MCF-7) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP15154 | Dehydrogenase/reductase SDR family member 13 (DHRS13) | C174 | 11.2 | |||
| LDTP00464 | Glutathione S-transferase 3, mitochondrial (MGST3) | C56 | 5.3 | |||
| LDTP01268 | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) | C106 | 3.7 | |||
| LDTP11248 | Probable ATP-dependent RNA helicase DDX23 (DDX23) | C692 | 3.4 | |||
| LDTP04358 | Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) | C96 | 3.2 | |||
| LDTP09053 | Xyloside xylosyltransferase 1 (XXYLT1) | C10 | 3.0 | |||
| LDTP01783 | Aspartate aminotransferase, mitochondrial (GOT2) | C106 | 2.8 | |||
| LDTP11243 | Glucose-6-phosphatase 3 (G6PC3) | C269 | 2.8 | |||
| LDTP09841 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3) | C21 | 2.8 | |||
| LDTP10077 | Patatin-like phospholipase domain-containing protein 2 (PNPLA2) | C412 | 2.4 | |||
| LDTP06101 | Fas-activated serine/threonine kinase (FASTK) | C212 | 2.4 | |||
| LDTP00293 | Cytochrome c oxidase subunit NDUFA4 (NDUFA4) | C44 | 2.3 | |||
| LDTP02733 | Pyruvate kinase PKM (PKM) | C49 | 2.3 | |||
| LDTP01503 | Mitofusin-2 (MFN2) | C8 | 2.2 | |||
| LDTP03332 | Proteasome subunit alpha type-3 (PSMA3) | C42 | 2.2 | |||
| LDTP10049 | FAST kinase domain-containing protein 4 (TBRG4) | C335 | 2.2 | |||
| LDTP09216 | Serine palmitoyltransferase small subunit B (SPTSSB) | C68 | 2.1 | |||
| LDTP06787 | Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) | C265 | 2.1 | |||
| LDTP05481 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) | C55 | 2.1 | |||
Transporter and channel
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP11213 | Nucleoporin NDC1 (NDC1) | C9 | 3.3 | |||
| LDTP05511 | Cytoskeleton-associated protein 4 (CKAP4) | C100 | 3.1 | |||
| LDTP12909 | Mitochondrial carrier homolog 1 (MTCH1) | C385 | 2.6 | |||
| LDTP11213 | Nucleoporin NDC1 (NDC1) | C468 | 2.0 | |||
| LDTP02262 | Heat shock protein HSP 90-beta (HSP90AB1) | C412 | 2.0 | |||
Other
| Target ID | Target Name | Binding Sites | Binding Ratio | |||
|---|---|---|---|---|---|---|
| LDTP05257 | Receptor expression-enhancing protein 5 (REEP5) | C18 | 4.8 | |||
| LDTP13269 | Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) | C86 | 4.7 | |||
| LDTP15887 | Lipase maturation factor 2 (LMF2) | C659 | 4.3 | |||
| LDTP11304 | Mitochondrial import inner membrane translocase subunit Tim21 (TIMM21) | C192 | 3.7 | |||
| LDTP06277 | Mortality factor 4-like protein 2 (MORF4L2) | C165 | 3.4 | |||
| LDTP04935 | Prefoldin subunit 3 (VBP1) | C113 | 2.7 | |||
| LDTP05533 | Kinesin light chain 1 (KLC1) | C55 | 2.6 | |||
| LDTP19324 | Vesicle transport protein SFT2C (SFT2D3) | C67 | 2.4 | |||
| LDTP17132 | Ubiquinol-cytochrome c reductase complex assembly factor 4 (UQCC4) | C6 | 2.2 | |||
| LDTP06543 | DNA damage-binding protein 1 (DDB1) | C128 | 2.2 | |||
| LDTP05186 | Large ribosomal subunit protein eL24 (RPL24) | C36 | 2.2 | |||
| LDTP00911 | Double-strand-break repair protein rad21 homolog (RAD21) | C585 | 2.2 | |||
| LDTP04027 | Matrin-3 (MATR3) | C563 | 2.2 | |||
| LDTP06983 | Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) | C844 | 2.1 | |||
| LDTP02164 | Nucleophosmin (NPM1) | C275 | 2.1 | |||