Details of the Target
General Information of Target
| Target ID | LDTP17132 | |||||
|---|---|---|---|---|---|---|
| Target Name | Ubiquinol-cytochrome c reductase complex assembly factor 4 (UQCC4) | |||||
| Gene Name | UQCC4 | |||||
| Gene ID | 283951 | |||||
| Synonyms |
C16orf91; CCSMST1; Ubiquinol-cytochrome c reductase complex assembly factor 4; Protein CCSMST1 |
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| 3D Structure | ||||||
| Sequence |
MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLALKNPNKR
LEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYT GQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNK SKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVR GESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVR KSMSHQAAIASQRFEGTTSLGEVRTPSQLSDNNCRQ |
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| Target Bioclass |
Other
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| Family |
UQCC4 family
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| Subcellular location |
Mitochondrion inner membrane
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| Function |
Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IPM Probe Info |
 |
C6(2.25) | LDD0379 | [1] | |
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IA-alkyne Probe Info |
 |
N.A. | LDD0161 | [2] | |
|
TFBX Probe Info |
 |
N.A. | LDD0027 | [3] | |
Competitor(s) Related to This Target
References