Details of the Probe

General Information of Probe

Probe ID
LDPC0565
Probe Name
C343
Synonyms
Z4282860542
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 355.5
Lipid-water partition coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C21H29N3O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-spiro[adamantane-2,2'-morpholine]-4'-ylpropan-1-one
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CCOC3(C2)C4CC5CC(C4)CC3C5
InChI
InChI=1S/C21H29N3O2/c1-2-3-5-20(22-23-20)6-4-19(25)24-7-8-26-21(14-24)17-10-15-9-16(12-17)13-18(21)11-15/h1,15-18H,3-14H2
InChIKey
QYQDNXMJOXQUBQ-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

125 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 12.73  LDD2005 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 13.55  LDD2005 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 15.67  LDD2005 
Acid ceramidase (ASAH1) LDTP05905 24.42  LDD2005 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 11.63  LDD2005 
ADP-dependent glucokinase (ADPGK) LDTP11127 32.90  LDD2005 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 30.27  LDD2005 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 12.47  LDD2005 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 12.55  LDD2005 
Atlastin-2 (ATL2) LDTP09251 14.22  LDD2005 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 26.72  LDD2005 
Beta-galactosidase (GLB1) LDTP02837 11.08  LDD2005 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 11.39  LDD2005 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 13.93  LDD2005 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 20.68  LDD2005 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 14.93  LDD2005 
Calcyclin-binding protein (CACYBP) LDTP12163 17.75  LDD2005 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 25.63  LDD2005 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 12.47  LDD2005 
Cartilage-associated protein (CRTAP) LDTP01300 15.56  LDD2005 
Catechol O-methyltransferase (COMT) LDTP03145 13.55  LDD2005 
Ceramide glucosyltransferase (UGCG) LDTP06617 16.80  LDD2005 
Ceramide synthase 2 (CERS2) LDTP10329 13.83  LDD2005 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 11.08  LDD2005 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 16.80  LDD2005 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 37.27  LDD2005 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 51.98  LDD2005 
Cytochrome b5 type B (CYB5B) LDTP00697 60.55  LDD2005 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 12.47  LDD2005 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 19.56  LDD2005 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 38.85  LDD2005 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 12.38  LDD2005 
Delta(24)-sterol reductase (DHCR24) LDTP06375 12.82  LDD2005 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 12.21  LDD2005 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 11.55  LDD2005 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 19.84  LDD2005 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 18.25  LDD2005 
E3 ubiquitin-protein ligase UBR1 (UBR1) LDTP08564 18.77  LDD2005 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 34.54  LDD2005 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 34.78  LDD2005 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 13.93  LDD2005 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 28.64  LDD2005 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 19.84  LDD2005 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 17.15  LDD2005 
Glutathione hydrolase 7 (GGT7) LDTP13367 15.45  LDD2005 
Glutathione S-transferase A4 (GSTA4) LDTP00575 68.12  LDD2005 
Glycogenin-1 (GYG1) LDTP04119 11.63  LDD2005 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 17.51  LDD2005 
Helicase MOV-10 (MOV10) LDTP12233 11.79  LDD2005 
Heme A synthase COX15 (COX15) LDTP07931 31.12  LDD2005 
Heme oxygenase 1 (HMOX1) LDTP02359 22.63  LDD2005 
Heme oxygenase 2 (HMOX2) LDTP03540 27.47  LDD2005 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 13.64  LDD2005 
Hexokinase-2 (HK2) LDTP04531 12.47  LDD2005 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 11.79  LDD2005 
Holocytochrome c-type synthase (HCCS) LDTP04581 22.94  LDD2005 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 39.95  LDD2005 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 17.88  LDD2005 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 12.55  LDD2005 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 13.93  LDD2005 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 17.15  LDD2005 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 11.88  LDD2005 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 20.97  LDD2005 
Lysosomal acid phosphatase (ACP2) LDTP02539 13.45  LDD2005 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 11.16  LDD2005 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.83  LDD2005 
Lysosomal protective protein (CTSA) LDTP02505 22.63  LDD2005 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 18.64  LDD2005 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) LDTP00975 24.08  LDD2005 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 33.13  LDD2005 
Mitochondrial disaggregase (CLPB) LDTP11683 11.31  LDD2005 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 18.77  LDD2005 
N-alpha-acetyltransferase 35, NatC auxiliary subunit (NAA35) LDTP07259 14.62  LDD2005 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 18.64  LDD2005 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 24.93  LDD2005 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 13.09  LDD2005 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 12.47  LDD2005 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 37.01  LDD2005 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 13.09  LDD2005 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 11.71  LDD2005 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 18.90  LDD2005 
Nucleoredoxin (NXN) LDTP07367 14.12  LDD2005 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 40.79  LDD2005 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 11.39  LDD2005 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 14.72  LDD2005 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 30.70  LDD2005 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 11.47  LDD2005 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 14.72  LDD2005 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 19.97  LDD2005 
Phospholipase A2 group XV (PLA2G15) LDTP09088 11.24  LDD2005 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 11.63  LDD2005 
Plasma membrane calcium-transporting ATPase 1 (ATP2B1) LDTP03024 11.55  LDD2005 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 12.91  LDD2005 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 24.42  LDD2005 
Presequence protease, mitochondrial (PITRM1) LDTP07003 17.15  LDD2005 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 12.73  LDD2005 
Prostaglandin reductase 3 (PTGR3) LDTP15422 18.51  LDD2005 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 19.29  LDD2005 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 11.88  LDD2005 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 12.55  LDD2005 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 23.10  LDD2005 
Pseudouridylate synthase 7 homolog (PUS7) LDTP10709 15.45  LDD2005 
Ras-related protein Rab-11B (RAB11B) LDTP06501 14.12  LDD2005 
Ras-related protein Rab-24 (RAB24) LDTP10020 12.47  LDD2005 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 19.56  LDD2005 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 23.75  LDD2005 
Ribonucleases P/MRP protein subunit POP1 (POP1) LDTP10903 12.21  LDD2005 
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) LDTP07989 13.45  LDD2005 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 14.72  LDD2005 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 15.03  LDD2005 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 13.93  LDD2005 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 14.03  LDD2005 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 19.97  LDD2005 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 18.38  LDD2005 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 13.55  LDD2005 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 25.81  LDD2005 
Squalene monooxygenase (SQLE) LDTP06142 18.38  LDD2005 
Thimet oligopeptidase (THOP1) LDTP04542 27.67  LDD2005 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 13.45  LDD2005 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 19.16  LDD2005 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 14.52  LDD2005 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 13.09  LDD2005 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 14.93  LDD2005 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 48.17  LDD2005 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 20.53  LDD2005 
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⏷ Show the Full List of 125 Enzyme
88 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 12.38  LDD2005 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 12.47  LDD2005 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 19.16  LDD2005 
ATP synthase subunit a (MT-ATP6) LDTP01804 15.56  LDD2005 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 11.63  LDD2005 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 29.04  LDD2005 
BRI3-binding protein (BRI3BP) LDTP15648 33.13  LDD2005 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 20.25  LDD2005 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 13.93  LDD2005 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 20.82  LDD2005 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 14.62  LDD2005 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 31.56  LDD2005 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 16.91  LDD2005 
Derlin-1 (DERL1) LDTP11245 22.01  LDD2005 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 38.85  LDD2005 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 15.89  LDD2005 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 15.56  LDD2005 
Importin-4 (IPO4) LDTP09515 13.00  LDD2005 
Importin-8 (IPO8) LDTP00630 13.93  LDD2005 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 16.34  LDD2005 
Lysosome membrane protein 2 (SCARB2) LDTP06034 14.42  LDD2005 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 20.82  LDD2005 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 15.03  LDD2005 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 32.00  LDD2005 
Metaxin-1 (MTX1) LDTP05900 28.84  LDD2005 
MICOS complex subunit MIC26 (APOO) LDTP11250 22.32  LDD2005 
MICOS complex subunit MIC60 (IMMT) LDTP06660 11.63  LDD2005 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 13.74  LDD2005 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 16.00  LDD2005 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 21.41  LDD2005 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 14.52  LDD2005 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 64.45  LDD2005 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 23.75  LDD2005 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 19.70  LDD2005 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 19.97  LDD2005 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 18.64  LDD2005 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 19.84  LDD2005 
Mpv17-like protein 2 (MPV17L2) LDTP14952 18.64  LDD2005 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 12.21  LDD2005 
Nucleoporin NDC1 (NDC1) LDTP11213 12.73  LDD2005 
Nucleoporin NUP35 (NUP35) LDTP09204 11.63  LDD2005 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 15.03  LDD2005 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 11.08  LDD2005 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 13.93  LDD2005 
PRA1 family protein 2 (PRAF2) LDTP01060 13.00  LDD2005 
Prohibitin 1 (PHB1) LDTP03717 20.82  LDD2005 
Prosaposin (PSAP) LDTP02215 28.44  LDD2005 
Protein GPR107 (GPR107) LDTP07236 16.22  LDD2005 
Protein GPR108 (GPR108) LDTP12383 38.32  LDD2005 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 48.84  LDD2005 
Protein tweety homolog 3 (TTYH3) LDTP11615 42.81  LDD2005 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 18.13  LDD2005 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 21.71  LDD2005 
Reticulon-1 (RTN1) LDTP06633 38.32  LDD2005 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 17.03  LDD2005 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 21.26  LDD2005 
Sideroflexin-4 (SFXN4) LDTP07531 11.63  LDD2005 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 23.92  LDD2005 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 35.26  LDD2005 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 31.34  LDD2005 
Sortilin (SORT1) LDTP10885 11.88  LDD2005 
Sorting nexin-27 (SNX27) LDTP10533 13.55  LDD2005 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 15.45  LDD2005 
Stomatin (STOM) LDTP03380 12.21  LDD2005 
SUN domain-containing protein 1 (SUN1) LDTP01454 11.55  LDD2005 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 16.56  LDD2005 
Syntaxin-6 (STX6) LDTP00857 15.35  LDD2005 
Tetraspanin-10 (TSPAN10) LDTP15967 33.82  LDD2005 
Tetraspanin-3 (TSPAN3) LDTP16813 22.94  LDD2005 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 36.00  LDD2005 
Translocation protein SEC63 homolog (SEC63) LDTP13243 15.03  LDD2005 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 49.87  LDD2005 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 15.56  LDD2005 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 12.04  LDD2005 
Transmembrane protein 126A (TMEM126A) LDTP15948 21.11  LDD2005 
Transmembrane protein 160 (TMEM160) LDTP20002 44.02  LDD2005 
Transmembrane protein 214 (TMEM214) LDTP07477 11.96  LDD2005 
Transmembrane protein 230 (TMEM230) LDTP10065 20.97  LDD2005 
Transmembrane protein 33 (TMEM33) LDTP04787 13.18  LDD2005 
Transmembrane protein 59 (TMEM59) LDTP11406 16.00  LDD2005 
Transmembrane protein 87A (TMEM87A) LDTP15481 36.25  LDD2005 
Transportin-1 (TNPO1) LDTP09949 14.93  LDD2005 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 13.74  LDD2005 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 33.59  LDD2005 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 32.67  LDD2005 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 17.51  LDD2005 
Wolframin (WFS1) LDTP01380 12.38  LDD2005 
Zinc transporter 7 (SLC30A7) LDTP09180 19.03  LDD2005 
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⏷ Show the Full List of 88 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DNA polymerase epsilon subunit 4 (POLE4) LDTP12471 11.16  LDD2005 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 22.78  LDD2005 
Transcription factor AP-4 (TFAP4) LDTP05307 12.55  LDD2005 
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1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Golgi pH regulator B (GPR89B) LDTP14610 11.63  LDD2005 
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3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 16.11  LDD2005 
Leukocyte surface antigen CD47 (CD47) LDTP05572 13.55  LDD2005 
Neuroplastin (NPTN) LDTP14205 12.64  LDD2005 
------------------------------------------------------------------------------------
84 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 33.36  LDD2005 
Anaphase-promoting complex subunit 2 (ANAPC2) LDTP13412 11.31  LDD2005 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 17.75  LDD2005 
Ankyrin repeat and SOCS box protein 6 (ASB6) LDTP12741 17.88  LDD2005 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 12.04  LDD2005 
BLOC-2 complex member HPS6 (HPS6) LDTP08420 11.63  LDD2005 
Borealin (CDCA8) LDTP06915 13.74  LDD2005 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 37.01  LDD2005 
Centrin-2 (CETN2) LDTP03926 11.88  LDD2005 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.91  LDD2005 
Coiled-coil domain-containing protein 97 (CCDC97) LDTP19860 11.31  LDD2005 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 17.27  LDD2005 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 14.32  LDD2005 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 36.50  LDD2005 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 16.22  LDD2005 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 14.83  LDD2005 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 18.38  LDD2005 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 38.59  LDD2005 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 85.04  LDD2005 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 14.42  LDD2005 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 15.24  LDD2005 
Fanconi anemia group A protein (FANCA) LDTP00618 15.14  LDD2005 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 12.55  LDD2005 
Ganglioside GM2 activator (GM2A) LDTP02927 23.92  LDD2005 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 21.71  LDD2005 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 17.15  LDD2005 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 13.36  LDD2005 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 12.47  LDD2005 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 13.64  LDD2005 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 12.47  LDD2005 
Large ribosomal subunit protein mL40 (MRPL40) LDTP12395 14.32  LDD2005 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 45.25  LDD2005 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 11.31  LDD2005 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 20.68  LDD2005 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 19.97  LDD2005 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 22.32  LDD2005 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 11.79  LDD2005 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 14.52  LDD2005 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 12.04  LDD2005 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 13.00  LDD2005 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2005 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 58.49  LDD2005 
Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) LDTP08874 11.31  LDD2005 
Neuferricin (CYB5D2) LDTP15623 16.11  LDD2005 
Nicastrin (NCSTN) LDTP09787 12.21  LDD2005 
Nucleobindin-1 (NUCB1) LDTP05375 38.05  LDD2005 
Nucleobindin-2 (NUCB2) LDTP05160 79.89  LDD2005 
Nucleolar protein 9 (NOP9) LDTP15283 15.35  LDD2005 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 16.11  LDD2005 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 15.35  LDD2005 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 13.83  LDD2005 
Optic atrophy 3 protein (OPA3) LDTP16006 31.34  LDD2005 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 17.27  LDD2005 
Protein CEBPZOS (CEBPZOS) LDTP18883 30.70  LDD2005 
Protein CutA (CUTA) LDTP01075 11.39  LDD2005 
Protein FAM114A2 (FAM114A2) LDTP16080 23.26  LDD2005 
Protein FAM162A (FAM162A) LDTP10056 37.27  LDD2005 
Protein FAM177A1 (FAM177A1) LDTP15398 13.74  LDD2005 
Protein jagunal homolog 1 (JAGN1) LDTP08904 26.72  LDD2005 
Protein LYRIC (MTDH) LDTP08224 15.56  LDD2005 
Protein MTSS 2 (MTSS2) LDTP07916 15.03  LDD2005 
Protein unc-119 homolog B (UNC119B) LDTP00105 20.97  LDD2005 
Protein UXT (UXT) LDTP13125 11.63  LDD2005 
Protein YIF1A (YIF1A) LDTP01494 16.34  LDD2005 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 17.88  LDD2005 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 22.47  LDD2005 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 13.36  LDD2005 
Reticulocalbin-2 (RCN2) LDTP06097 12.13  LDD2005 
Reticulon-2 (RTN2) LDTP01167 14.52  LDD2005 
Reticulon-3 (RTN3) LDTP01522 60.13  LDD2005 
Reticulon-4 (RTN4) LDTP12412 21.41  LDD2005 
SHC SH2 domain-binding protein 1 (SHCBP1) LDTP17808 11.16  LDD2005 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 31.12  LDD2005 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 15.35  LDD2005 
Splicing factor 3B subunit 5 (SF3B5) LDTP11328 19.84  LDD2005 
Synaptogyrin-2 (SYNGR2) LDTP00859 22.78  LDD2005 
Syntaxin-18 (STX18) LDTP13086 49.87  LDD2005 
Tetraspanin-6 (TSPAN6) LDTP14458 39.40  LDD2005 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 17.63  LDD2005 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 18.25  LDD2005 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 11.47  LDD2005 
TraB domain-containing protein (TRABD) LDTP19963 27.67  LDD2005 
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) LDTP12830 15.89  LDD2005 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 38.85  LDD2005 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2005 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587