Details of the Target

General Information of Target

Target ID LDTP17808
Target Name SHC SH2 domain-binding protein 1 (SHCBP1)
Gene Name SHCBP1
Gene ID 79801
Synonyms
SHC SH2 domain-binding protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPGPPGSLEMGPLTFRDVAIEFSLEEWQCLDTAQRNLYRKVMFENYRNLVFLGIAVSKPH
LITCLEQGKEPWNRKRQEMVAKPPVIYSHFTEDLWPEHSIKDSFQKVILRGYGKCGHENL
QLRISCKSVDESKVFKEGYNELNQCLRTTQSKIFQCDKYVKVFHKFSNSNSHKKRNTGKK
VFKCKECGKSFCMLSHLTQHIRIHTRENSYKCEECGKVLNWFSELIKHKGIHMGEKPYKC
EECGKAFNQSSTLIKHKKIHIEEKPFKCEECGKAFSLFSILSKHKIIHTGDKPYKCDECH
KAFNWFATLTNHKRIHTGEKPFKCEECGKDFNQFSNLTKHKKIHTGEKPYKCEECGKAFN
QFANLTRHKKIHTGEKSYKCEECGKAFIQSSNLTEHMRIHTGEKPYKCEECGKAFNGCSS
LTRHKRIHTRENTYKCEECGKGFTLFSTLTNHKVIHTGEKSYKCDECGNVFNWPATLANH
KRIHAREKPYKCEECGKAFNRSSHLTRHKKIHTGEKLYKPEKCDNNFDNT
Target Type
Literature-reported
Target Bioclass
Other
Subcellular location
Midbody
Function
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells.
TTD ID
T96542
Uniprot ID
Q8NEM2
DrugMap ID
TTZ9WGL
Ensemble ID
ENST00000303383.8
HGNC ID
HGNC:29547

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 15 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		11.80  LDD0402  [1]
BTD
 Probe Info  		C599(0.76)  LDD2099  [2]
AHL-Pu-1
 Probe Info  		C591(4.86)  LDD0168  [3]
DBIA
 Probe Info  		C43(1.34); C46(1.34)  LDD0078  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		C353(0.00); C591(0.00); C254(0.00)  LDD0038  [5]
IA-alkyne
 Probe Info  		C426(0.00); C591(0.00); C353(0.00)  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		C93(0.00); C353(0.00)  LDD0037  [5]
NAIA_4
 Probe Info  		C591(0.00); C612(0.00)  LDD2226  [6]
IPM
 Probe Info  		C271(0.00); C612(0.00); C599(0.00)  LDD0147  [7]
TFBX
 Probe Info  		C271(0.00); C353(0.00)  LDD0148  [7]
VSF
 Probe Info  		N.A.  LDD0007  [8]
Acrolein
 Probe Info  		N.A.  LDD0217  [9]
Methacrolein
 Probe Info  		N.A.  LDD0218  [9]
AOyne
 Probe Info  		15.00  LDD0443  [10]
NAIA_5
 Probe Info  		N.A.  LDD2223  [6]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C228
 Probe Info  		15.78  LDD1901  [11]
C343
 Probe Info  		11.16  LDD2005  [11]
C344
 Probe Info  		4.92  LDD2006  [11]
C386
 Probe Info  		8.06  LDD2045  [11]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C591(4.86)  LDD0168  [3]
 LDCM0026  4SU-RNA+native RNA HEK-293T C599(2.20); C591(6.85)  LDD0169  [3]
 LDCM0214  AC1 HCT 116 C150(0.70); C161(0.67); C271(0.70); C353(1.26)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C150(0.67); C161(0.71); C271(1.22); C353(1.11)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C150(0.65); C161(0.65); C271(0.94); C353(0.82)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C150(0.56); C161(0.56); C271(1.07); C353(0.88)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C150(0.57); C161(0.57); C271(1.00); C353(0.82)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C150(0.53); C161(0.53); C271(1.27); C353(0.95)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C150(0.59); C161(0.59); C271(0.98); C353(0.66)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C150(0.51); C161(0.51); C271(0.97); C353(0.79)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C150(0.52); C161(0.52); C271(1.22); C353(1.04)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C150(0.59); C161(0.59); C271(1.03); C353(0.84)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C150(0.62); C161(0.62); C271(1.00); C353(0.82)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C150(0.71); C161(0.71); C271(1.01); C353(0.88)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C150(0.69); C161(0.71); C271(1.25); C353(0.96)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C150(0.64); C161(0.64); C271(0.98); C353(0.90)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C150(0.61); C161(0.61); C271(0.95); C353(0.82)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C150(0.57); C161(0.57); C271(1.36); C353(0.80)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C150(0.92); C161(0.91); C271(0.82); C353(1.03)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C150(0.65); C161(0.66); C271(0.90); C353(0.96)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C150(0.60); C161(0.63); C271(0.99); C353(0.90)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C150(0.62); C161(0.64); C271(1.04); C353(0.77)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C150(0.74); C161(0.74); C271(1.06); C353(0.87)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C150(0.70); C161(0.69); C271(0.96); C353(0.99)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C150(0.68); C161(0.69); C271(1.05); C353(1.04)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C150(0.80); C161(0.78); C271(1.10); C353(1.07)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C150(0.72); C161(0.74); C271(0.82); C353(1.03)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C150(0.98); C161(0.88); C271(0.94); C353(0.99)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C150(0.80); C161(0.82); C271(0.96); C353(1.12)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C150(0.99); C161(0.88); C271(0.95); C353(0.98)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C150(0.91); C161(0.85); C271(0.95); C353(1.21)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C150(0.92); C161(0.92); C271(0.91); C353(1.00)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C150(0.73); C161(0.73); C271(0.91); C353(0.99)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C150(0.70); C161(0.69); C271(0.98); C353(1.09)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C150(1.02); C161(1.02); C271(1.20); C353(0.63)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C150(1.02); C161(1.02); C271(0.76); C353(0.88)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C150(0.77); C161(0.77); C271(1.03); C353(0.71)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C150(1.24); C161(1.24); C271(0.88); C353(1.38)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C150(0.88); C161(0.88); C271(0.92); C353(0.92)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C150(0.86); C161(0.86); C271(1.00); C353(1.00)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C150(0.83); C161(0.83); C271(1.05); C353(1.12)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C150(0.86); C161(0.86); C271(0.96); C353(0.73)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C150(0.79); C161(0.79); C271(0.94); C353(1.17)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C150(0.84); C161(0.84); C271(0.91); C353(1.13)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C150(0.85); C161(0.85); C271(0.96); C353(0.77)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C150(0.79); C161(0.79); C271(1.00); C353(1.17)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C150(0.81); C161(0.86); C271(1.46); C353(1.03)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C150(0.76); C161(0.76); C271(1.07); C353(1.22)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C150(0.86); C161(0.86); C271(1.00); C353(1.07)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C150(1.01); C161(1.01); C271(0.92); C353(1.11)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C150(0.59); C161(0.59); C93(0.72); C426(0.76)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C150(0.39); C161(0.39); C510(0.62); C426(0.64)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C150(0.55); C161(0.55); C464(0.79); C353(0.82)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C150(0.35); C161(0.35); C510(0.71); C500(0.74)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C150(0.41); C161(0.41); C500(0.73); C510(0.73)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C150(0.40); C161(0.40); C353(0.63); C426(0.73)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C150(0.34); C161(0.34); C510(0.68); C500(0.69)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C426(0.84); C150(0.86); C500(0.89); C510(0.89)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C150(0.47); C161(0.47); C426(0.75); C93(0.84)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C150(0.56); C161(0.56); C353(0.74); C500(0.80)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C150(0.40); C161(0.40); C353(0.60); C426(0.67)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C150(0.43); C161(0.43); C93(0.45); C426(0.72)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C150(0.39); C161(0.39); C271(1.34); C353(0.63)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C150(0.42); C161(0.42); C271(1.21); C353(0.66)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C150(0.70); C161(0.70); C271(1.03); C353(0.82)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C150(0.76); C161(0.76); C271(1.38); C353(0.75)  LDD2161  [4]
 LDCM0276  AC17 HCT 116 C426(0.72); C271(0.85); C500(0.86); C510(0.86)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C426(0.61); C161(0.74); C150(0.77); C460(0.93)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C426(0.65); C500(0.78); C510(0.78); C460(0.85)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C150(0.65); C161(0.66); C500(0.71); C510(0.71)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C426(0.68); C271(0.84); C93(0.87); C460(0.90)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C426(0.59); C460(0.79); C464(0.79); C161(0.84)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C426(0.63); C271(0.82); C93(0.91); C500(0.95)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C426(0.59); C460(0.88); C464(0.88); C271(0.89)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C426(0.69); C271(0.93); C500(0.96); C510(0.96)  LDD0601  [4]
 LDCM0285  AC25 HCT 116 C500(0.76); C510(0.76); C150(0.82); C161(0.84)  LDD0602  [4]
 LDCM0286  AC26 HCT 116 C161(0.67); C93(0.68); C150(0.73); C500(0.74)  LDD0603  [4]
 LDCM0287  AC27 HCT 116 C93(0.66); C500(0.66); C510(0.66); C161(0.67)  LDD0604  [4]
 LDCM0288  AC28 HCT 116 C161(0.65); C150(0.67); C93(0.70); C426(0.82)  LDD0605  [4]
 LDCM0289  AC29 HCT 116 C93(0.64); C161(0.71); C500(0.71); C510(0.71)  LDD0606  [4]
 LDCM0290  AC3 HCT 116 C161(0.66); C150(0.69); C271(0.73); C500(0.76)  LDD0607  [4]
 LDCM0291  AC30 HCT 116 C150(0.61); C161(0.64); C93(0.66); C500(0.75)  LDD0608  [4]
 LDCM0292  AC31 HCT 116 C161(0.61); C93(0.64); C150(0.64); C500(0.67)  LDD0609  [4]
 LDCM0293  AC32 HCT 116 C161(0.50); C150(0.51); C93(0.60); C500(0.62)  LDD0610  [4]
 LDCM0294  AC33 HCT 116 C93(0.58); C161(0.64); C500(0.67); C510(0.67)  LDD0611  [4]
 LDCM0295  AC34 HCT 116 C93(0.60); C161(0.64); C150(0.67); C460(0.75)  LDD0612  [4]
 LDCM0296  AC35 HCT 116 C426(0.86); C271(0.93); C93(0.99); C353(0.99)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C353(0.75); C426(0.75); C93(0.88); C271(0.93)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C500(0.72); C510(0.72); C426(0.73); C93(0.86)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C93(0.85); C500(0.88); C510(0.88); C271(0.88)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C426(0.74); C150(0.82); C161(0.84); C93(0.90)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C161(0.61); C500(0.66); C510(0.66); C150(0.67)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C353(0.70); C426(0.77); C500(0.83); C510(0.83)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C93(0.76); C500(0.78); C510(0.78); C46(0.86)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C353(0.77); C93(0.78); C500(0.81); C510(0.81)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C93(0.81); C500(0.83); C510(0.83); C353(0.84)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C500(0.76); C510(0.76); C93(0.78); C161(0.91)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C500(0.78); C510(0.78); C93(0.86); C426(0.87)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C500(0.84); C510(0.84); C93(0.92); C161(0.93)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C161(0.81); C500(0.81); C510(0.81); C150(0.87)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C500(0.73); C510(0.73); C43(0.90); C161(0.92)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C161(0.95); C150(0.99); C500(1.03); C510(1.03)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C161(0.59); C500(0.63); C510(0.63); C271(0.63)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C161(0.85); C500(0.85); C510(0.85); C46(0.87)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C43(0.73); C46(0.79); C353(0.81); C500(0.93)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C93(0.84); C500(0.85); C510(0.85); C353(0.90)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C500(0.82); C510(0.82); C46(1.01); C43(1.03)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C161(0.81); C150(0.86); C46(0.97); C43(0.98)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C500(0.87); C510(0.87); C161(0.93); C150(0.98)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C353(0.89); C161(0.99); C500(1.09); C510(1.09)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C426(0.47); C500(0.62); C510(0.62); C161(0.69)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C426(0.42); C500(0.62); C510(0.62); C161(0.76)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C426(0.62); C500(0.66); C510(0.66); C161(0.67)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C150(0.68); C161(0.71); C500(0.75); C510(0.75)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C426(0.56); C500(0.62); C510(0.62); C161(0.71)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C426(0.50); C500(0.60); C510(0.60); C161(0.69)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C426(0.53); C500(0.57); C510(0.57); C161(0.69)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C426(0.41); C500(0.59); C510(0.59); C93(0.70)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C426(0.56); C500(0.62); C510(0.62); C161(0.77)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C500(0.57); C510(0.57); C161(0.62); C150(0.65)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C500(0.57); C510(0.57); C426(0.72); C161(0.77)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C500(0.65); C510(0.65); C161(0.69); C426(0.69)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C353(0.85); C161(0.87); C150(0.91); C46(0.96)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C150(0.95); C161(0.95); C43(0.95); C500(0.97)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C93(0.81); C500(0.83); C510(0.83); C150(0.84)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C161(0.68); C150(0.75); C353(0.79); C460(0.91)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C43(0.82); C46(0.88); C161(0.93); C93(0.99)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C161(0.79); C43(0.81); C150(0.83); C93(0.87)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C161(0.85); C150(0.86); C93(0.90); C500(0.91)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C161(0.90); C43(0.92); C150(0.92); C93(1.04)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C353(0.78); C161(0.87); C93(0.90); C150(0.91)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C500(0.83); C510(0.83); C150(0.85); C161(0.86)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C93(0.81); C43(0.82); C161(0.84); C150(0.86)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C161(0.73); C150(0.84); C93(0.89); C353(0.92)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C353(0.77); C43(0.82); C93(0.85); C161(0.87)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C426(0.70); C150(0.76); C161(0.77); C93(0.79)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C161(0.87); C150(0.91); C353(0.91); C500(0.94)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C93(0.94); C46(0.98); C43(0.99); C353(1.06)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C161(0.84); C150(0.89); C93(0.98); C353(1.06)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C150(0.46); C161(0.46); C460(0.70); C464(0.70)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C150(0.50); C161(0.50); C460(0.62); C464(0.62)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C150(0.51); C161(0.51); C460(0.64); C464(0.64)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C150(0.56); C161(0.56); C500(0.78); C510(0.78)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C150(0.71); C161(0.71); C460(0.79); C464(0.79)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C150(0.61); C161(0.61); C460(0.64); C464(0.64)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C150(0.60); C161(0.60); C426(0.67); C460(0.68)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C353(1.05); C271(1.06); C500(1.09); C510(1.09)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C150(0.52); C161(0.52); C426(0.72); C460(0.77)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C150(0.54); C161(0.54); C426(0.65); C500(0.75)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C150(0.63); C161(0.63); C460(0.64); C464(0.64)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C460(0.66); C464(0.66); C150(0.69); C161(0.69)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C150(0.51); C161(0.51); C460(0.65); C464(0.65)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C150(0.54); C161(0.54); C426(0.68); C500(0.72)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C150(0.47); C161(0.47); C460(0.60); C464(0.60)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C150(0.44); C161(0.44); C93(0.57); C500(0.61)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C93(0.62); C150(0.66); C161(0.66); C353(0.69)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C150(0.81); C161(0.80); C271(1.13); C353(1.28)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C500(0.76); C510(0.76); C150(0.77); C161(0.80)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C150(0.61); C161(0.72); C426(0.80); C500(0.85)  LDD0592  [4]
 LDCM0156  Aniline NCI-H1299 N.A.  LDD0404  [1]
 LDCM0020  ARS-1620 HCC44 C43(1.34); C46(1.34)  LDD0078  [4]
 LDCM0367  CL1 HCT 116 C271(0.91); C500(0.92); C510(0.92); C93(0.95)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C500(0.72); C510(0.72); C150(0.87); C460(0.89)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C161(0.67); C500(0.67); C510(0.67); C150(0.67)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C150(0.72); C161(0.77); C426(0.79); C500(0.93)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C93(0.87); C500(0.90); C510(0.90); C150(0.90)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C150(0.90); C500(0.90); C510(0.90); C161(0.90)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C353(0.81); C150(0.82); C426(0.86); C161(0.87)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C426(0.70); C500(0.77); C510(0.77); C161(0.79)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C150(0.66); C161(0.66); C426(0.68); C460(0.77)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C426(0.59); C161(0.62); C150(0.63); C500(0.76)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C426(0.72); C161(0.77); C460(0.81); C464(0.81)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C426(0.58); C150(0.76); C161(0.76); C500(0.81)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C500(0.80); C510(0.80); C150(0.91); C271(0.96)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C426(0.64); C500(0.78); C510(0.78); C161(0.81)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C426(0.62); C150(0.83); C460(0.84); C464(0.84)  LDD0698  [4]
 LDCM0382  CL112 HCT 116 C93(0.81); C150(0.86); C43(0.97); C161(0.98)  LDD0699  [4]
 LDCM0383  CL113 HCT 116 C93(0.61); C161(0.61); C150(0.68); C460(0.78)  LDD0700  [4]
 LDCM0384  CL114 HCT 116 C93(0.66); C161(0.66); C150(0.69); C460(0.75)  LDD0701  [4]
 LDCM0385  CL115 HCT 116 C150(0.69); C161(0.69); C93(0.71); C460(0.83)  LDD0702  [4]
 LDCM0386  CL116 HCT 116 C161(0.67); C150(0.68); C500(0.76); C510(0.76)  LDD0703  [4]
 LDCM0387  CL117 HCT 116 C353(0.82); C93(0.95); C426(1.05); C161(1.10)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C426(0.77); C93(0.80); C161(0.81); C150(0.89)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C426(0.85); C353(0.86); C500(0.89); C510(0.89)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C150(0.76); C500(0.81); C510(0.81); C271(0.87)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C500(0.75); C510(0.75); C93(0.80); C161(0.87)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C500(1.08); C510(1.08); C271(1.15); C93(1.15)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C161(0.81); C93(0.85); C46(0.90); C150(0.93)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C93(0.95); C500(0.99); C510(0.99); C161(1.18)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C353(0.81); C500(0.86); C510(0.86); C161(0.87)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C500(0.71); C510(0.71); C426(0.81); C460(0.91)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C426(0.51); C500(0.70); C510(0.70); C161(0.70)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C426(0.52); C161(0.62); C500(0.65); C510(0.65)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C426(0.60); C500(0.62); C510(0.62); C161(0.74)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C500(0.75); C510(0.75); C150(0.91); C353(0.92)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C500(0.68); C510(0.68); C150(0.94); C460(0.96)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C500(0.75); C510(0.75); C271(0.88); C464(0.89)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C500(0.79); C510(0.79); C426(0.81); C460(0.89)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C460(0.77); C464(0.77); C500(0.78); C510(0.78)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C460(0.61); C464(0.61); C500(0.64); C510(0.64)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C353(0.69); C500(0.75); C510(0.75); C426(0.82)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C93(0.90); C500(0.91); C510(0.91); C46(0.97)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C500(0.69); C510(0.69); C353(0.75); C426(0.80)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C500(0.68); C510(0.68); C426(0.82); C460(0.83)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C500(0.81); C510(0.81); C271(0.90); C353(0.94)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C500(0.74); C510(0.74); C460(0.79); C464(0.79)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C150(0.86); C161(0.86); C271(0.98); C353(0.82)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C150(0.83); C161(0.83); C271(1.12); C353(0.83)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C150(0.89); C161(0.89); C271(0.99); C353(0.84)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C150(1.00); C161(1.00); C271(1.23); C353(1.01)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C150(0.82); C161(0.82); C271(1.10); C353(1.34)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C150(0.83); C161(0.83); C271(0.97); C353(0.87)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C150(0.94); C161(0.99); C271(0.96); C353(0.93)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C150(0.75); C161(0.75); C271(0.86); C353(0.86)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C150(0.94); C161(0.88); C271(0.91); C353(0.77)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C150(0.81); C161(0.74); C271(0.87); C353(0.76)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C150(1.06); C161(0.92); C271(0.88); C353(1.02)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C150(0.89); C161(0.81); C271(0.94); C353(1.03)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C150(0.83); C161(0.78); C271(0.97); C353(0.82)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C150(1.00); C161(0.86); C271(0.91); C353(0.89)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C150(0.89); C161(0.80); C271(0.87); C353(0.94)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C150(0.87); C161(0.77); C271(0.87); C353(0.89)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C150(1.05); C161(1.17); C271(0.71); C353(1.06)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C150(0.87); C161(0.72); C271(0.84); C353(1.16)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C150(0.94); C161(0.79); C271(0.89); C353(0.83)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C150(1.06); C161(0.91); C271(0.82); C353(0.89)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C150(0.95); C161(0.83); C271(0.96); C353(1.03)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C150(0.90); C161(0.80); C271(0.80); C353(0.78)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C150(0.94); C161(0.87); C271(0.87); C353(0.96)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C150(1.39); C161(1.42); C353(0.91); C43(1.37)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C150(1.23); C161(1.25); C353(0.97); C43(1.05)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C150(1.49); C161(1.67); C353(1.03); C43(1.01)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C150(1.21); C161(1.18); C353(1.04); C43(1.41)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C150(0.94); C161(0.93); C271(0.87); C353(0.96)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C150(1.26); C161(1.33); C353(0.75); C43(0.99)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C150(1.22); C161(1.25); C353(0.75); C43(1.03)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C150(1.09); C161(1.13); C353(1.07); C43(1.14)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C150(1.41); C161(1.43); C353(1.10); C43(1.24)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C150(1.45); C161(1.59); C353(0.74); C43(1.12)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C150(1.34); C161(1.37); C353(0.82); C43(1.03)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C150(1.10); C161(1.13); C353(1.05); C43(1.06)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C150(1.40); C161(1.51); C353(0.90); C43(1.09)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C150(1.22); C161(1.28); C353(0.92); C43(1.07)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C150(1.16); C161(1.17); C353(1.01); C43(1.30)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C150(0.85); C161(0.92); C271(0.78); C353(1.05)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C150(1.16); C161(1.15); C353(1.00); C43(1.11)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C150(0.82); C161(0.82); C271(1.16); C353(0.88)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C150(0.86); C161(0.86); C271(0.97); C353(0.83)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C150(0.70); C161(0.70); C271(1.12); C353(0.66)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C150(0.67); C161(0.67); C271(1.19); C353(0.91)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C150(0.82); C161(0.82); C271(1.31); C353(0.86)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C150(0.63); C161(0.63); C271(1.56); C353(0.84)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C150(0.74); C161(0.74); C271(1.19); C353(0.75)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C150(0.70); C161(0.70); C271(1.06); C353(0.72)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C150(0.86); C161(0.86); C271(1.08); C353(0.81)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C150(0.81); C161(0.84); C271(0.87); C353(1.24)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C150(0.73); C161(0.73); C271(1.17); C353(0.83)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C150(0.86); C161(0.86); C271(1.31); C353(0.74)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C150(0.85); C161(0.85); C271(1.11); C353(0.81)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C150(1.56); C161(1.56); C271(1.25); C353(0.71)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C150(0.89); C161(0.89); C271(1.24); C353(0.75)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C150(0.90); C161(0.90); C43(0.93); C46(0.94)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C150(3.04); C161(3.04); C43(0.98); C46(0.98)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C150(0.85); C161(0.85); C43(1.04); C46(1.04)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C150(0.72); C161(0.72); C43(1.01); C46(1.02)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C150(1.49); C161(1.30); C271(0.79); C353(1.06)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C150(0.98); C161(0.98); C43(0.89); C46(0.90)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C150(0.76); C161(0.76); C43(1.01); C46(1.01)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C150(0.84); C161(0.84); C43(1.19); C46(1.16)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C150(0.87); C161(0.87); C43(1.17); C46(1.14)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C150(0.94); C161(0.94); C43(1.24); C46(1.23)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C150(0.85); C161(0.85); C43(1.10); C46(1.07)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C150(0.96); C161(0.96); C43(0.94); C46(0.93)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C150(0.85); C161(0.85); C43(1.07); C46(1.06)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C150(1.03); C161(1.03); C43(1.28); C46(1.26)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C150(1.09); C161(1.09); C43(1.66); C46(1.63)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C150(0.95); C161(1.01); C271(1.22); C353(1.07)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C150(1.20); C161(1.20); C43(0.90); C46(0.91)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C150(0.73); C161(0.72); C271(0.71); C353(1.22)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C150(0.97); C161(0.97); C271(0.74); C353(1.10)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C150(1.04); C161(1.10); C271(0.71); C353(1.13)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C150(0.90); C161(0.88); C271(0.65); C353(0.96)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C150(0.83); C161(0.85); C271(0.74); C353(0.99)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C150(0.69); C161(0.65); C271(0.71); C353(1.15)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C150(0.78); C161(0.70); C271(0.74); C353(1.12)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C150(0.67); C161(0.60); C271(0.78); C353(1.15)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C150(0.67); C161(0.65); C271(0.70); C353(1.15)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C254(1.03); C93(0.78); C612(1.09); C161(1.06)  LDD1698  [12]
 LDCM0468  Fragment33 HCT 116 C150(0.75); C161(0.75); C271(1.04); C353(0.80)  LDD0785  [4]
 LDCM0427  Fragment51 HCT 116 C150(0.99); C161(0.90); C271(0.73); C353(0.81)  LDD0744  [4]
 LDCM0022  KB02 HCT 116 C43(3.14); C46(2.83)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C43(1.75); C46(1.66)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C43(2.29); C46(2.02)  LDD0082  [4]
 LDCM0109  NEM HeLa N.A.  LDD0225  [9]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C599(0.76)  LDD2099  [2]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C599(0.44)  LDD2125  [2]
 LDCM0131  RA190 MM1.R C612(1.70)  LDD0304  [13]
 LDCM0021  THZ1 HCT 116 C43(1.24); C46(1.24)  LDD2173  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein kinase C beta type (PRKCB) AGC Ser/Thr protein kinase family P05771

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD044402
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